Publications by authors named "M C D N J M Huysmans"

247 Publications

Systematic review and meta-analysis of diagnostic methods for occlusal surface caries.

Clin Oral Investig 2021 Jun 14. Epub 2021 Jun 14.

Department of Conservative Dentistry and Periodontology, University Hospital, Ludwig-Maximilian University, Munich, Germany.

Aim: This systematic review and meta-analysis aimed to assess the diagnostic performance of commonly used methods for occlusal caries diagnostics, such as visual examination (VE), bitewing radiography (BW) and laser fluorescence (LF), in relation to their ability to detect (dentin) caries under clinical and laboratory conditions.

Materials And Methods: A systematic search of the literature was performed to identify studies meeting the inclusion criteria using the PIRDS concept (N = 1090). A risk of bias (RoB) assessment tool was used for quality evaluation. Reports with low/moderate RoB, well-matching thresholds for index and reference tests and appropriate reporting were included in the meta-analysis (N = 37; 29 in vivo/8 in vitro). The pooled sensitivity (SE), specificity (SP), diagnostic odds ratio (DOR) and areas under ROC curves (AUCs) were computed.

Results: SP ranged from 0.50 (fibre-optic transillumination/caries detection level) to 0.97 (conventional BW/dentine detection level) in vitro. AUCs were typically higher for BW or LF than for VE. The highest AUC of 0.89 was observed for VE at the 1/3 dentin caries detection level; SE (0.70) was registered to be higher than SP (0.47) for VE at the caries detection level in vivo.

Conclusion: The number of included studies was found to be low. This underlines the need for high-quality caries diagnostic studies that further provide data in relation to multiple caries thresholds.

Clinical Relevance: VE, BW and LF provide acceptable measures for their diagnostic performance on occlusal surfaces, but the results should be interpreted with caution due to the limited data in many categories.
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http://dx.doi.org/10.1007/s00784-021-04024-1DOI Listing
June 2021

The effect of pre-treatment levels of tooth wear and the applied increase in the vertical dimension of occlusion (VDO) on the survival of direct resin composite restorations.

J Dent 2021 Jun 5:103712. Epub 2021 Jun 5.

Department of Dentistry, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.

Objectives: To investigate the effects of the level of pre-treatment tooth wear and increasing the VDO on the performance of direct resin composite restorations for the rehabilitation of pathological tooth wear.

Methods: Full-mouth (pre-treatment) grading was performed on digital greyscale scan records for 34 participants (35.3 ± 8.4 years) with signs of moderate-to-severe generalised tooth wear, using the Tooth Wear Evaluation System and the Basic Erosive Wear Examination. Each participant received full-mouth direct resin composite restorations, with increased VDO. The post-treatment increase in the VDO was determined. Recalls were planned after 1 month, and after 1, 3, and 5 years. Three 'levels' of restoration failure were described. The effects of the variables on the frequencies of restoration failure were calculated with a multivariable Cox regression, (p < 0.05).

Results: 1269 restorations were placed with a mean observation period of 62.4 months. Increasing the VDO by 1mm significantly reduced the risks of all levels of anterior restoration failure (HR ≤ 0.62, p ≤ 0.025). A higher anterior BEWE surface score was associated with increased risks of Level 2- & 3- failures, (HR ≥ 1.29, p ≤ 0.019). Premolar restorations showed lower risks of Level 2- & 3- failure, compared to the molar restorations, (HR ≤ 0.5, p ≤ 0.005).

Conclusion: Levels of pre-treatment wear and the applied change in the VDO significantly affected failure risk.

Clinical Relevance: Direct resin composite restorations for the rehabilitation of wear should be made as voluminous as possible, respecting the presenting biological, functional, and aesthetic constraints.
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http://dx.doi.org/10.1016/j.jdent.2021.103712DOI Listing
June 2021

Optimization and validation of a LaBr(Ce) detector model for use in Monte Carlo simulations.

Appl Radiat Isot 2021 Aug 25;174:109790. Epub 2021 May 25.

Department of Hydrology and Hydraulic Engineering, Vrije Universiteit Brussel (VUB), Pleinlaan 2, BE-1050, Brussels, Belgium.

A reliable detector model is needed for Monte Carlo efficiency calibration. A LaBr(Ce) detector model was optimized and verified using different radioactive sources (Am,Ba,Cs,Co andEu) and geometries (point, extended and surface). PENELOPE and MCNP were used for Monte Carlo simulations. A good agreement was observed between simulated and experimental full energy peak efficiencies (FEPE) as their mean relative difference was 2.84% ± 1.93% and 2.79% ± 1.99% for PENELOPE and MCNP simulation, respectively. The differences between simulated FEPEs of two Monte Carlo codes were negligible except for low energies (< 100 keV).
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http://dx.doi.org/10.1016/j.apradiso.2021.109790DOI Listing
August 2021

A randomized controlled trial of manual versus powered tooth brushing during haematopoietic stem cell transplantation.

Oral Dis 2021 May 8. Epub 2021 May 8.

Department of Dentistry, Radboudumc, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.

Aim: To compare manual and powered tooth brushing (MT and PT) with respect to patient compliance to brushing frequency advice, plaque removal and severity of oral mucositis (OM) in patients undergoing hematopoietic stem cell transplantation (HSCT) after high-dose chemotherapy.

Materials & Methods: A randomized controlled trial was conducted. Forty-six patients scheduled to receive myeloablative conditioning regimen before autologous HSCT were included and randomly assigned to control (MT, n = 23) or test (PT, n = 23) groups. Starting at day 1 (day of hospital admission for HSCT), brushing frequency (patient recorded diary), plaque scores (Plaque Control Index) and oral mucositis (Oral Mucositis Nursing Index) were recorded daily. Data for days 1 to 17 were analysed using regression analysis and general linear models.

Results: Few patients maintained 4 times per day brushing, but most brushed at least 2 times per day throughout the study. In PT, overall plaque scores were lower by 6.98% (p = .006) as compared to MT. No differences were seen in OM scores between the groups (p = .968). A small but significant positive correlation was found between plaque scores and OM severity: R =0.15 (p < .01).

Conclusions: Powered tooth brushing resulted in lower plaque scores, but was not associated with reduced OM severity. Individual plaque scores were positively related to OM severity.
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http://dx.doi.org/10.1111/odi.13899DOI Listing
May 2021

[Self-reported oral health and oral health behaviour of asylum seekers].

Ned Tijdschr Tandheelkd 2021 Mar;128(3):154-160

In order to assess the oral health and oral health behaviour of asylum seekers in the Netherlands, 542 asylum seekers completed questionnaires. There were questionnaires for the groups children (1-11 years), youths (12-17 years) and adults (18+ years). 4 Categories of questions were asked: 'demographic characteristics', 'complaints and symptoms', 'lifestyle and knowledge' and 'visiting the dentist'. Regression analyses were performed to see which demographic factors influenced oral health. Of the respondents, 42% of the children, 57% of the youths and 86% of the adults reported at least one oral complaint or symptom. Of them 42% of the children, 59% of the youths and 53% of the adults followed the basic recommendation to brush their teeth twice a day. Of those questioned, 45% of the children, 48% of the youths and 28% of the adults went to a dentist for check-ups. When these results are compared to the rest of the Dutch population, asylum seekers scored worse in all categories.
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http://dx.doi.org/10.5177/ntvt.2021.03.20082DOI Listing
March 2021