Publications by authors named "M A Gusev"

117 Publications

A simplified cluster model and a tool adapted for collaborative labeling of lung cancer CT scans.

Comput Methods Programs Biomed 2021 Jul 18;206:106111. Epub 2021 Apr 18.

Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department, Petrovka str., 24, Moscow, 127051, Russia; Federal Research Center "Computer Science and Control" of Russian Academy of Sciences, Vavilova str., 44/2, Moscow, 119333, Russia. Electronic address:

Background And Objective: Lung cancer is the most common type of cancer with a high mortality rate. Early detection using medical imaging is critically important for the long-term survival of the patients. Computer-aided diagnosis (CAD) tools can potentially reduce the number of incorrect interpretations of medical image data by radiologists. Datasets with adequate sample size, annotation, and truth are the dominant factors in developing and training effective CAD algorithms. The objective of this study was to produce a practical approach and a tool for the creation of medical image datasets.

Methods: The proposed model uses the modified maximum transverse diameter approach to mark a putative lung nodule. The modification involves the possibility to use a set of overlapping spheres of appropriate size to approximate the shape of the nodule. The algorithm embedded in the model also groups the marks made by different readers for the same lesion. We used the data of 536 randomly selected patients of Moscow outpatient clinics to create a dataset of standard-dose chest computed tomography (CT) scans utilizing the double-reading approach with arbitration. Six volunteer radiologists independently produced a report for each scan using the proposed model with the main focus on the detection of lesions with sizes ranging from 3 to 30 mm. After this, an arbitrator reviewed their marks and annotations.

Results: The maximum transverse diameter approach outperformed the alternative methods (3D box, ellipsoid, and complete outline construction) in a study of 10,000 computer-generated tumor models of different shapes in terms of accuracy and speed of nodule shape approximation. The markup and annotation of the CTLungCa-500 dataset revealed 72 studies containing no lung nodules. The remaining 464 CT scans contained 3151 lesions marked by at least one radiologist: 56%, 14%, and 29% of the lesions were malignant, benign, and non-nodular, respectively. 2887 lesions have the target size of 3-30 mm. Only 70 nodules were uniformly identified by all the six readers. An increase in the number of independent readers providing CT scans interpretations led to an accuracy increase associated with a decrease in agreement. The dataset markup process took three working weeks.

Conclusions: The developed cluster model simplifies the collaborative and crowdsourced creation of image repositories and makes it time-efficient. Our proof-of-concept dataset provides a valuable source of annotated medical imaging data for training CAD algorithms aimed at early detection of lung nodules. The tool and the dataset are publicly available at https://github.com/Center-of-Diagnostics-and-Telemedicine/FAnTom.git and https://mosmed.ai/en/datasets/ct_lungcancer_500/, respectively.
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http://dx.doi.org/10.1016/j.cmpb.2021.106111DOI Listing
July 2021

Improving the QRS detection for one-channel ECG sensor.

Technol Health Care 2019 ;27(6):623-642

We analyzed several QRS detection algorithms in order to build a quality industrial beat detector, intended for a small, wearable, one channel electrocardiogram sensor with a sampling rate of 125 Hz, and analog-to-digital conversion of 10 bits. The research was a lengthy process that included building several hundred rules to cope with the QRS detection problems and finding an optimal threshold value for several parameters. We obtained 99.90% QRS sensitivity and 99.90% QRS positive predictive rate measured on the first channel of rescaled and resampled MIT-BIH Arrhythmia ECG database. Even more so, our solution works better than the algorithms for the original signals with a sampling rate of 360 Hz and analog-to-digital conversion of 11 bits.
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http://dx.doi.org/10.3233/THC-181589DOI Listing
May 2020

A Novel Scheme of Thermographic Microimaging Using Pyro-Magneto-Optical Indicator Films.

Adv Mater 2015 Sep 21;27(34):5017-22. Epub 2015 Jul 21.

Nanoscale Magnetic Materials - Magnetic Domains, Institute for Materials Science, University of Kiel, 24143, Kiel, Germany.

A new method of imaging of temperature distributions is presented. The method is based on the use of a BiLu2 Fe4 GaO12 ferrimagnetic garnet layer as a pyro-magneto-optical detection layer. Thermal imaging with high sensitivity, with micrometer spatial and with millisecond temporal resolution is demonstrated in a contactless read-out scheme.
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http://dx.doi.org/10.1002/adma.201501859DOI Listing
September 2015

Separate recording of rationally related vibration frequencies using digital stroboscopic holographic interferometry.

Appl Opt 2009 Jun;48(18):3475-80

Imanuil Kant Russian State University, Nevsky str., 14, 236041, Kaliningrad, Russia.

A method for separate recording of rationally related vibration frequencies is presented. To record and measure the mode shape of vibrations, a synchronized stroboscopic CCD camera is used. Synchronization and control of the camera acquisition for recording stroboscopic holographic sequence has been realized. The phase for different states of the object vibration is calculated using the Fourier-transform method. Experimental results are presented, and the advantages and disadvantages of the proposed method are discussed.
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http://dx.doi.org/10.1364/ao.48.003475DOI Listing
June 2009

[Use of white turpentine bath emulsion and yellow turpentine solution for the treatment of chronic prostatitis complicated by excretory pathospermia].

Vopr Kurortol Fizioter Lech Fiz Kult 2009 Mar-Apr(2):31-3

The paper reports a review of up-to-date methods for the use of white turpentine bath emulsion and yellow turpentine solution in the treatment of chronic prostatitis complicated by excretory pathospermia. The results of bath therapy are presented. It is shown that the efficiency of white turpentine bath emulsion amounted to 69.7% compared with 88.3% in patients treated with the use of yellow turpentine solution.
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July 2009