Lyudmila Tsurkan

Lyudmila Tsurkan

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Lyudmila Tsurkan

Lyudmila Tsurkan

Publications by authors named "Lyudmila Tsurkan"

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21Publications

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Targeting ALK in pediatric RMS does not induce antitumor activity in vivo.

Cancer Chemother Pharmacol 2018 08 31;82(2):251-263. Epub 2018 May 31.

Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN, 38105-2794, USA.

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http://dx.doi.org/10.1007/s00280-018-3615-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054567PMC
August 2018

Carboxylesterases: General detoxifying enzymes.

Chem Biol Interact 2016 Nov 15;259(Pt B):327-331. Epub 2016 Feb 15.

Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN 38105, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cbi.2016.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985501PMC
November 2016

Tumour-selective targeting of drug metabolizing enzymes to treat metastatic cancer.

Br J Pharmacol 2016 10 22;173(19):2811-8. Epub 2016 Aug 22.

Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, TN, USA.

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http://dx.doi.org/10.1111/bph.13553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5055134PMC
October 2016

Inhibition of human carboxylesterases hCE1 and hiCE by cholinesterase inhibitors.

Chem Biol Interact 2013 Mar 2;203(1):226-30. Epub 2012 Nov 2.

Department of Chemical Biology and Therapeutics, St Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1016/j.cbi.2012.10.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582710PMC
March 2013

Modulation of esterified drug metabolism by tanshinones from Salvia miltiorrhiza ("Danshen").

J Nat Prod 2013 Jan 3;76(1):36-44. Epub 2013 Jan 3.

Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1021/np300628aDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556224PMC
January 2013

ATP-dependent mitochondrial porphyrin importer ABCB6 protects against phenylhydrazine toxicity.

J Biol Chem 2012 Apr 31;287(16):12679-90. Epub 2012 Jan 31.

Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1074/jbc.M111.336180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3339991PMC
April 2012

Requirements for mammalian carboxylesterase inhibition by substituted ethane-1,2-diones.

Bioorg Med Chem 2011 Aug 4;19(15):4635-43. Epub 2011 Jul 4.

Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105-2794, USA.

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http://dx.doi.org/10.1016/j.bmc.2011.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139784PMC
August 2011

Requirements for mammalian carboxylesterase inhibition by substituted ethane-1,2-diones.

Bioorg Med Chem 2011 Aug 4;19(15):4635-43. Epub 2011 Jul 4.

Department of Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105-2794, USA.

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http://dx.doi.org/10.1016/j.bmc.2011.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139784PMC
August 2011

Directed assembly of sub-nanometer thin organic materials with programmed-size nanopores.

Angew Chem Int Ed Engl 2008 ;47(37):7036-9

Department of Chemistry, University of Memphis, Memphis, TN 38152, USA.

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http://dx.doi.org/10.1002/anie.200801814DOI Listing
October 2008

Analysis of the inhibition of mammalian carboxylesterases by novel fluorobenzoins and fluorobenzils.

Bioorg Med Chem 2007 Jun 12;15(11):3801-17. Epub 2007 Mar 12.

Department of Molecular Pharmacology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1016/j.bmc.2007.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995442PMC
June 2007

Selective inhibition of carboxylesterases by isatins, indole-2,3-diones.

J Med Chem 2007 Apr 23;50(8):1876-85. Epub 2007 Mar 23.

Department of Molecular Pharmacology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105-2794, and Department of Chemistry and Biochemistry, University of Mississippi, University, Mississippi 38677, USA.

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http://dx.doi.org/10.1021/jm061471kDOI Listing
April 2007

Intracellular inhibition of carboxylesterases by benzil: modulation of CPT-11 cytotoxicity.

Mol Cancer Ther 2006 Sep;5(9):2281-8

Department of Molecular Pharmacology, St. Jude Children's Research Hospital, 332 North Lauderdale, Memphis, TN 38105-2794, USA.

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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-06
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http://dx.doi.org/10.1158/1535-7163.MCT-06-0160DOI Listing
September 2006

Inhibition of acetylcholinesterase by the anticancer prodrug CPT-11.

Chem Biol Interact 2005 Dec 28;157-158:247-52. Epub 2005 Oct 28.

Department of Molecular Pharmacology, St. Jude Children's Research Hospital, 332 N. Lauderdale, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1016/j.cbi.2005.10.033DOI Listing
December 2005