Lynn M Schuchter

Lynn M Schuchter

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Lynn M Schuchter

Lynn M Schuchter

Publications by authors named "Lynn M Schuchter"

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69Publications

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Best Practices for Reducing Unplanned Acute Care for Patients With Cancer.

J Oncol Pract 2018 May 17;14(5):306-313. Epub 2018 Apr 17.

University of Pennsylvania, Philadelphia, PA.

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May 2018

Acute visual loss after ipilimumab treatment for metastatic melanoma.

J Immunother Cancer 2016 18;4:66. Epub 2016 Oct 18.

Division of Hematology/Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA USA ; Present address: Division of Hematology/Oncology, Department of Internal Medicine, University of Michigan, C366 MIB 1500 E. Medical Center Drive, SPC5848, Ann Arbor, MI 48109 USA.

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February 2018

Association of First-in-Class Immune Checkpoint Inhibition and Targeted Therapy With Survival in Patients With Stage IV Melanoma.

JAMA Oncol 2018 Jan;4(1):126-128

Department of Surgery, Division of Endocrine and Oncologic Surgery, Hospital of the University of Pennsylvania, Philadelphia.

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January 2018

Adjuvant Melanoma Therapy - Head-Spinning Progress.

Authors:
Lynn M Schuchter

N Engl J Med 2017 11;377(19):1888-1890

From the University of Pennsylvania Abramson Cancer Center, Philadelphia.

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November 2017

ACUTE EXUDATIVE PARANEOPLASTIC POLYMORPHOUS VITELLIFORM MACULOPATHY DURING VEMURAFENIB AND PEMBROLIZUMAB TREATMENT FOR METASTATIC MELANOMA.

Retin Cases Brief Rep 2017 Jun 13. Epub 2017 Jun 13.

*Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Philadelphia, Pennsylvania; †Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania; and ‡Division of Hematology Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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June 2017

Reaffirming and Clarifying the American Society of Clinical Oncology's Policy Statement on the Critical Role of Phase I Trials in Cancer Research and Treatment.

J Clin Oncol 2017 Jan 28;35(2):139-140. Epub 2016 Nov 28.

Jeffrey S. Weber, New York University Langone Medical Center, New York, NY; Laura A. Levit, American Society of Clinical Oncology, Alexandria, VA; Peter C. Adamson, The Children's Hospital of Philadelphia, Philadelphia, PA; Suanna S. Bruinooge, American Society of Clinical Oncology, Alexandria, VA; Howard A. Burris III, Sarah Cannon Research Institute, Nashville, TN; Michael A. Carducci, Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD; Adam P. Dicker, Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA; Mithat Gönen, Memorial Sloan Kettering Cancer Center, New York, NY; Stephen M. Keefe, University of Pennsylvania, Philadelphia, PA; Michael A. Postow, Memorial Sloan Kettering Cancer Center, New York, NY; Michael A. Thompson, Aurora Health Care, Milwaukee, WI; David M. Waterhouse, Oncology Hematology Care, Cincinnati, OH; Susan L. Weiner, Children's Cause for Cancer Advocacy, Washington, DC; and Lynn M. Schuchter, University of Pennsylvania, Philadelphia, PA.

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January 2017

Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade.

Cell 2016 Dec;167(6):1540-1554.e12

Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Parker Institute for Cancer Immunotherapy, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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December 2016

Histopathologic and mutational analysis of a case of blue nevus-like melanoma.

J Cutan Pathol 2016 Sep 8;43(9):776-80. Epub 2016 Jun 8.

Department of Dermatology, University of Pennsylvania, Philadelphia, PA, USA.

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September 2016

Cutaneous autoimmune effects in the setting of therapeutic immune checkpoint inhibition for metastatic melanoma.

J Cutan Pathol 2016 Sep 1;43(9):787-91. Epub 2016 Jun 1.

Department of Dermatology, University of Pennsylvania, Philadelphia, PA, USA.

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September 2016

Enhancing the evaluation of PI3K inhibitors through 3D melanoma models.

Pigment Cell Melanoma Res 2016 May 21;29(3):317-28. Epub 2016 Mar 21.

Program of Cellular and Molecular Oncogenesis, Melanoma Research Center, The Wistar Institute, Philadelphia, PA, USA.

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May 2016

Oncogenic BRAF-Mediated Melanoma Cell Invasion.

Cell Rep 2016 05 19;15(9):2012-24. Epub 2016 May 19.

Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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May 2016

Copy Number Changes Are Associated with Response to Treatment with Carboplatin, Paclitaxel, and Sorafenib in Melanoma.

Clin Cancer Res 2016 Jan 25;22(2):374-82. Epub 2015 Aug 25.

Translational Medicine and Human Genetics, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania. Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

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January 2016

Chemotherapy for Melanoma.

Cancer Treat Res 2016 ;167:209-29

Division of Hematology/Oncology, Department of Medicine, Abramson Cancer Center of the University of Pennsylvania, 3400 Civic Center Blvd, 1218 Penn Tower, Philadelphia, PA, 19104, USA.

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January 2016

Phase I/II Trial of Imatinib and Bevacizumab in Patients With Advanced Melanoma and Other Advanced Cancers.

Oncologist 2015 Aug 17;20(8):952-9. Epub 2015 Jun 17.

Developmental Therapeutics Program, Abramson Cancer Center of the University of Pennsylvania, Philadelphia, Pennsylvania, USA; Cancer Therapeutics Evaluation Program, National Cancer Institute, Bethesda, Maryland, USA.

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August 2015

Broad Applicability of Nivolumab in Melanoma Regardless of BRAF Mutation Status.

JAMA Oncol 2015 Jul;1(4):427-8

Division of Hematology-Oncology, Department of Medicine, Abramson Cancer Center, University of Pennsylvania, Philadelphia.

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July 2015

Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer.

Nature 2015 Apr 9;520(7547):373-7. Epub 2015 Mar 9.

1] Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA [2] Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA [3] Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA [4] Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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April 2015

Effects of tailored risk communications for skin cancer prevention and detection: the PennSCAPE randomized trial.

Cancer Epidemiol Biomarkers Prev 2015 Feb 28;24(2):415-21. Epub 2014 Nov 28.

Massachusetts General Hospital, Boston, Massachusetts.

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February 2015

American Society of Clinical Oncology policy statement update: the critical role of phase I trials in cancer research and treatment.

J Clin Oncol 2015 Jan 15;33(3):278-84. Epub 2014 Dec 15.

Jeffrey S. Weber, H. Lee Moffitt Cancer Center, Tampa, FL; Laura A. Levit and Suanna Bruinooge, American Society of Clinical Oncology, Alexandria, VA; Peter C. Adamson, Children's Hospital of Philadelphia; Adam P. Dicker, Jefferson Medical College, Thomas Jefferson University; Stephen M. Keefe and Lynn M. Schuchter, University of Pennsylvania, Philadelphia, PA; Howard A. Burris IIII, Sarah Cannon Research Institute, Nashville, TN; Michael A. Carducci, Johns Hopkins Sidney Kimmel Cancer Center, Baltimore, MD; Mithat Gönen and Michael A. Postow, Memorial Sloan-Kettering Cancer Center, New York, NY; Michael A. Thompson, Aurora Health Care, Milwaukee, WI; David M. Waterhouse, Oncology Hematology Care, Cincinnati, OH; and Susan L. Weiner, Children's Cause for Cancer Advocacy, Washington, DC.

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January 2015

Immune activation and a 9-year ongoing complete remission following CD40 antibody therapy and metastasectomy in a patient with metastatic melanoma.

Cancer Immunol Res 2014 Nov 24;2(11):1051-8. Epub 2014 Sep 24.

Abramson Cancer Center, University of Pennsylvania, Philadelphia. Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia. Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

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November 2014

Correlation of somatic mutations and clinical outcome in melanoma patients treated with Carboplatin, Paclitaxel, and sorafenib.

Clin Cancer Res 2014 Jun 8;20(12):3328-37. Epub 2014 Apr 8.

Authors' Affiliations: Hematology/Oncology, Department of Medicine, University of Pennsylvania; Translational Medicine and Human Genetics, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania; Abramson Cancer Center of the University of Pennsylvania, Philadelphia; University of Pittsburgh School of Medicine, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania; Dana Farber Cancer Institute; Massachusetts General Hospital Cancer Center, Massachusetts General Hospital, Boston, Massachusetts; Department of Pathology, Yale University School of Medicine; and Section of Medical Oncology, Yale Cancer Center, New Haven, ConnecticutAuthors' Affiliations: Hematology/Oncology, Department of Medicine, University of Pennsylvania; Translational Medicine and Human Genetics, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania; Abramson Cancer Center of the University of Pennsylvania, Philadelphia; University of Pittsburgh School of Medicine, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania; Dana Farber Cancer Institute; Massachusetts General Hospital Cancer Center, Massachusetts General Hospital, Boston, Massachusetts; Department of Pathology, Yale University School of Medicine; and Section of Medical Oncology, Yale Cancer Center, New Haven, Connecticut

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June 2014

What you are missing could matter: a rare, complex BRAF mutation affecting codons 599, 600, and 601 uncovered by next generation sequencing.

Cancer Genet 2014 Jun 18;207(6):272-5. Epub 2014 Jun 18.

Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

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June 2014

Hypoxia induces phenotypic plasticity and therapy resistance in melanoma via the tyrosine kinase receptors ROR1 and ROR2.

Cancer Discov 2013 Dec 8;3(12):1378-93. Epub 2013 Oct 8.

1Tumor Metastasis and Microenvironment Program and 2Molecular and Cellular Oncogenesis Program, The Wistar Institute; 3Abramson Cancer Center, University of Pennsylvania, Philadelphia; 4Lehigh Valley Health Network, Allentown, Pennsylvania; 5The National Institute on Aging, NIH, Baltimore, Maryland; and 6Dana-Farber/Harvard Cancer Center, Boston, Massachusetts.

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December 2013

Melanoma adapts to RAF/MEK inhibitors through FOXD3-mediated upregulation of ERBB3.

J Clin Invest 2013 May 1;123(5):2155-68. Epub 2013 Apr 1.

Department of Cancer Biology and Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA.

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May 2013

Melanoma genetic testing, counseling, and adherence to skin cancer prevention and detection behaviors.

Cancer Epidemiol Biomarkers Prev 2013 Apr 7;22(4):607-14. Epub 2013 Feb 7.

Perelman School of Medicine and School of Nursing, University of Pennsylvania, 801 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104, USA.

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April 2013

Phase III trial of carboplatin and paclitaxel with or without sorafenib in metastatic melanoma.

J Clin Oncol 2013 Jan 17;31(3):373-9. Epub 2012 Dec 17.

Massachusetts General Hospital, 55 Fruit St, Yawkey 9E, Boston, MA 02114, USA.

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January 2013

Diverse cutaneous side effects associated with BRAF inhibitor therapy: a clinicopathologic study.

J Am Acad Dermatol 2012 Dec 18;67(6):1265-72. Epub 2012 May 18.

Department of Dermatology, Hospital of University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

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December 2012

Phase II Trial of Temozolomide and Sorafenib in Advanced Melanoma Patients with or without Brain Metastases.

Clin Cancer Res 2009 Dec;15(24):7711-7718

Authors' Affiliations: Abramson Cancer Center at the University of Pennsylvania and Department of Medicine, Division of Medical Genetics, University of Pennsylvania, Philadelphia, Pennsylvania; and Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

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December 2009

Drug targeting of oncogenic pathways in melanoma.

Hematol Oncol Clin North Am 2009 Jun;23(3):599-618, x

Department of Medicine, Division of Hematology and Oncology, Abramson Cancer Center, University of Pennsylvania, 3400 Spruce Street, 16 Penn Tower, Philadelphia, PA 19104, USA.

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June 2009

Is 18F-FDG PET more accurate than standard diagnostic procedures in the detection of suspected recurrent melanoma?

J Nucl Med 2004 Aug;45(8):1323-7

Nuclear Medicine Division, Radiology Department, University of Pennsylvania, Philadelphia 19104, USA.

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August 2004

Adjuvant interferon therapy for melanoma: high-dose, low-dose, no dose, which dose?

Authors:
Lynn M Schuchter

J Clin Oncol 2004 Jan 9;22(1):7-10. Epub 2003 Dec 9.

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January 2004

Retransplantation of a cardiac allograft inadvertently harvested from a donor with metastatic melanoma.

Transplantation 2003 Aug;76(4):741-3

Division of Hematology/Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA. 19104.

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August 2003

P gene as an inherited biomarker of human eye color.

Cancer Epidemiol Biomarkers Prev 2002 Aug;11(8):782-4

Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.

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August 2002

Multiple primary melanoma revisited.

Cancer 2002 Apr;94(8):2248-55

Department of Medicine, Hematology-Oncology Division, University of Pennsylvania, Philadelphia, Pennsylvania 19104-6145, USA.

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April 2002