Publications by authors named "Lynley V Marshall"

31Publications

Reply to 'Comment on "Tumour-agnostic drugs in paediatric cancers"'.

Br J Cancer 2020 Oct 1. Epub 2020 Oct 1.

Paediatric and Adolescent Oncology Drug Development Team, Children and Young People's Unit, Royal Marsden Hospital and Institute of Cancer Research, Sutton, UK.

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http://dx.doi.org/10.1038/s41416-020-01104-zDOI Listing
October 2020

How to address challenges and opportunities in pediatric cancer drug development?

Expert Opin Drug Discov 2020 Aug 18;15(8):869-872. Epub 2020 May 18.

Division of Clinical Studies and Cancer Therapeutics, The Institute of Cancer Research , London, UK.

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http://dx.doi.org/10.1080/17460441.2020.1767064DOI Listing
August 2020

Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes.

Authors:
Matthew Clarke Alan Mackay Britta Ismer Jessica C Pickles Ruth G Tatevossian Scott Newman Tejus A Bale Iris Stoler Elisa Izquierdo Sara Temelso Diana M Carvalho Valeria Molinari Anna Burford Louise Howell Alex Virasami Amy R Fairchild Aimee Avery Jane Chalker Mark Kristiansen Kelly Haupfear James D Dalton Wilda Orisme Ji Wen Michael Hubank Kathreena M Kurian Catherine Rowe Mellissa Maybury Stephen Crosier Jeffrey Knipstein Ulrich Schüller Uwe Kordes David E Kram Matija Snuderl Leslie Bridges Andrew J Martin Lawrence J Doey Safa Al-Sarraj Christopher Chandler Bassel Zebian Claire Cairns Rachael Natrajan Jessica K R Boult Simon P Robinson Martin Sill Ira J Dunkel Stephen W Gilheeney Marc K Rosenblum Debbie Hughes Paula Z Proszek Tobey J Macdonald Matthias Preusser Christine Haberler Irene Slavc Roger Packer Ho-Keung Ng Shani Caspi Mara Popović Barbara Faganel Kotnik Matthew D Wood Lissa Baird Monika Ashok Davare David A Solomon Thale Kristin Olsen Petter Brandal Michael Farrell Jane B Cryan Michael Capra Michael Karremann Jens Schittenhelm Martin U Schuhmann Martin Ebinger Winand N M Dinjens Kornelius Kerl Simone Hettmer Torsten Pietsch Felipe Andreiuolo Pablo Hernáiz Driever Andrey Korshunov Lotte Hiddingh Barbara C Worst Dominik Sturm Marc Zuckermann Olaf Witt Tabitha Bloom Clare Mitchell Evelina Miele Giovanna Stefania Colafati Francesca Diomedi-Camassei Simon Bailey Andrew S Moore Timothy E G Hassall Stephen P Lowis Maria Tsoli Mark J Cowley David S Ziegler Matthias A Karajannis Kristian Aquilina Darren R Hargrave Fernando Carceller Lynley V Marshall Andreas von Deimling Christof M Kramm Stefan M Pfister Felix Sahm Suzanne J Baker Angela Mastronuzzi Andrea Carai Maria Vinci David Capper Sergey Popov David W Ellison Thomas S Jacques David T W Jones Chris Jones

Cancer Discov 2020 Jul 1;10(7):942-963. Epub 2020 Apr 1.

Division of Molecular Pathology, Institute of Cancer Research, London, United Kingdom.

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http://dx.doi.org/10.1158/2159-8290.CD-19-1030DOI Listing
July 2020

Sorafenib in pediatric hepatocellular carcinoma from a clinician perspective.

Pediatr Hematol Oncol 2020 Aug 17;37(5):412-423. Epub 2020 Mar 17.

The Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom.

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http://dx.doi.org/10.1080/08880018.2020.1740844DOI Listing
August 2020

Tumour-agnostic drugs in paediatric cancers.

Br J Cancer 2020 May 12;122(10):1425-1427. Epub 2020 Mar 12.

Paediatric and Adolescent Oncology Drug Development Team, Children and Young People's Unit, Royal Marsden Hospital and Institute of Cancer Research, Sutton, UK.

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http://dx.doi.org/10.1038/s41416-020-0770-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7217925PMC
May 2020

Challenging the indiscriminate use of temozolomide in pediatric high-grade gliomas: A review of past, current, and emerging therapies.

Pediatr Blood Cancer 2020 01 16;67(1):e28011. Epub 2019 Oct 16.

Children and Young People's Unit, The Royal Marsden NHS Foundation Trust, Sutton, United Kingdom.

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http://dx.doi.org/10.1002/pbc.28011DOI Listing
January 2020

High-dose etoposide and cyclophosphamide in adults and children with primary refractory and multiply relapsed acute leukaemias: The Royal Marsden experience.

Leuk Res 2019 10 13;85:106217. Epub 2019 Aug 13.

Paediatric Haemato-Oncology Department, The Royal Marsden NHS Foundation Trust, Downs Road, Sutton, London, SM2 5PT, United Kingdom; Division of Clinical Studies, The Institute of Cancer Research, 15 Cotswold Road, Sutton, London, SM2 5NG, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2019.106217DOI Listing
October 2019

10-year report on the European Paediatric Regulation and its impact on new drugs for children's cancers.

Lancet Oncol 2018 03;19(3):285-287

Innovative Therapy for Children with Cancer, Europe; SIOPE Brussels, Belgium; Department of Clinical Research, Gustave Roussy, Paris-Saclay University, Villejuif, France.

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http://dx.doi.org/10.1016/S1470-2045(18)30105-0DOI Listing
March 2018

Outcome of children and adolescents with central nervous system tumors in phase I trials.

J Neurooncol 2018 Mar 13;137(1):83-92. Epub 2017 Dec 13.

Pediatric and Adolescent Drug Development, Children and Young People's Unit, The Royal Marsden NHS Foundation Trust - Paediatric Offices, Downs Road, Sutton, SM2 5PT, UK.

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http://dx.doi.org/10.1007/s11060-017-2698-zDOI Listing
March 2018

In vitro nuclear magnetic resonance spectroscopy metabolic biomarkers for the combination of temozolomide with PI3K inhibition in paediatric glioblastoma cells.

PLoS One 2017 13;12(7):e0180263. Epub 2017 Jul 13.

Cancer Research UK Cancer Imaging Centre, Division of Radiotherapy and Imaging, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0180263PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509135PMC
September 2017

Targeted approaches to childhood cancer: progress in drug discovery and development.

Expert Opin Drug Discov 2015 May 3;10(5):483-95. Epub 2015 Apr 3.

The Royal Marsden NHS Foundation Trust, Children and Young People's Unit , Sutton, Surrey, SM2 5PT , UK +44 0 20 8915 6161 ;

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http://www.tandfonline.com/doi/full/10.1517/17460441.2015.10
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http://dx.doi.org/10.1517/17460441.2015.1025745DOI Listing
May 2015

Toxicity and outcome of children and adolescents participating in phase I/II trials of novel anticancer drugs: the Royal Marsden experience.

J Pediatr Hematol Oncol 2014 Apr;36(3):218-23

*Pediatric Drug Development Unit, Children and Young People's Unit, The Royal Marsden NHS Foundation Trust §Pediatric Drug Development Team, Divisions of Cancer Therapeutics and Clinical Studies, The Institute of Cancer Research, Sutton †Pediatric Oncology Department, Great Ormond Street Hospital ‡Institute of Child Health, University College London, London, UK.

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http://dx.doi.org/10.1097/MPH.0000000000000003DOI Listing
April 2014

At the frontier of progress for paediatric oncology: the neuroblastoma paradigm.

Br Med Bull 2013 7;108:173-88. Epub 2013 Nov 7.

Paediatric Drug Development Team, Di visions of Cancer Therapeutics and Clinical Studies, The Institute of Cancer Research, Sutton SM2 5NG, UK.

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http://dx.doi.org/10.1093/bmb/ldt033DOI Listing
July 2014