Publications

RANKL expressed on synovial fibroblasts is primarily responsible for bone erosions during joint inflammation.
Ann Rheum Dis 2016 Jun 29;75(6):1187-95. Epub 2015 May 29.
Department of Immunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Tokyo, Japan Explorative Research for Advanced Technology (ERATO) Program, Japan Science and Technology Agency (JST), Takayanagi Osteonetwork Project, Tokyo, Japan.

Inhibition of the TNF Family Cytokine RANKL Prevents Autoimmune Inflammation in the Central Nervous System.
Immunity 2015 Dec 8;43(6):1174-85. Epub 2015 Dec 8.
Department of Immunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Hongo 7-3-1, Bunkyo-ku, Tokyo 113-0033, Japan; Japan Science and Technology Agency (JST), Exploratory Research for Advanced Technology (ERATO) Program, Takayanagi Osteonetwork Project, Hongo 7-3-1, Bunkyo-ku, Tokyo, 113-0033, Japan. Electronic address:

Fezf2 Orchestrates a Thymic Program of Self-Antigen Expression for Immune Tolerance.
Cell 2015 Nov;163(4):975-87
Department of Immunology, Graduate School of Medicine and Faculty of Medicine, The University of Tokyo, Tokyo 113-0033, Japan; Takayanagi Osteonetwork Project, Exploratory Research for Advanced Technology Program, Japan Science and Technology Agency (JST), Tokyo 113-0033, Japan. Electronic address:


OX40L blockade is therapeutic in arthritis, despite promoting osteoclastogenesis.
Proc Natl Acad Sci U S A 2014 Feb 27;111(6):2289-94. Epub 2014 Jan 27.
Leukocyte Biology Section, National Heart and Lung Institute, Imperial College London, London SW7 2AZ, United Kingdom.

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