Lyne Khair

Lyne Khair

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Lyne Khair

Lyne Khair

Publications by authors named "Lyne Khair"

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15Publications

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Hypercholesterolemia Accelerates the Aging Phenotypes of Hematopoietic Stem Cells by a Tet1-Dependent Pathway.

Sci Rep 2020 02 27;10(1):3567. Epub 2020 Feb 27.

Division of Vascular and Endovascular Surgery, University of Massachusetts Medical School, Worcester, MA, 01655, USA.

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http://dx.doi.org/10.1038/s41598-020-60403-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7046636PMC
February 2020

The NuA4 acetyltransferase and histone H4 acetylation promote replication recovery after topoisomerase I-poisoning.

Epigenetics Chromatin 2019 04 16;12(1):24. Epub 2019 Apr 16.

Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, 245 N. 15th Street, Philadelphia, PA, 19102, USA.

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http://dx.doi.org/10.1186/s13072-019-0271-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6466672PMC
April 2019

Diabetes impairs wound healing by Dnmt1-dependent dysregulation of hematopoietic stem cells differentiation towards macrophages.

Nat Commun 2018 01 2;9(1):33. Epub 2018 Jan 2.

Diabetes Center of Excellence and Division of Vascular and Endovascular Surgery, University of Massachusetts Medical School, Worcester, MA, 01655, USA.

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http://dx.doi.org/10.1038/s41467-017-02425-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750226PMC
January 2018

Hypercholesterolemia Increases Colorectal Cancer Incidence by Reducing Production of NKT and γδ T Cells from Hematopoietic Stem Cells.

Cancer Res 2017 05 1;77(9):2351-2362. Epub 2017 Mar 1.

Diabetes Center of Excellence and Division of Vascular and Endovascular Surgery, University of Massachusetts Medical School, Worcester, Massachusetts.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-1916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193767PMC
May 2017

Nbs1 ChIP-Seq Identifies Off-Target DNA Double-Strand Breaks Induced by AID in Activated Splenic B Cells.

PLoS Genet 2015 Aug 11;11(8):e1005438. Epub 2015 Aug 11.

Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1005438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532491PMC
August 2015

ATM increases activation-induced cytidine deaminase activity at downstream S regions during class-switch recombination.

J Immunol 2014 May 11;192(10):4887-96. Epub 2014 Apr 11.

Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA 01605.

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http://dx.doi.org/10.4049/jimmunol.1303481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049217PMC
May 2014

AID recruits UNG and Msh2 to Ig switch regions dependent upon the AID C terminus [corrected].

J Immunol 2011 Sep 29;187(5):2464-75. Epub 2011 Jul 29.

Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA 01655, USA.

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http://dx.doi.org/10.4049/jimmunol.1101406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159830PMC
September 2011

Roles of the checkpoint sensor clamp Rad9-Rad1-Hus1 (911)-complex and the clamp loaders Rad17-RFC and Ctf18-RFC in Schizosaccharomyces pombe telomere maintenance.

Cell Cycle 2010 Jun 1;9(11):2237-48. Epub 2010 Jun 1.

Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133598PMC
http://dx.doi.org/10.4161/cc.9.11.11920DOI Listing
June 2010

Roles of heterochromatin and telomere proteins in regulation of fission yeast telomere recombination and telomerase recruitment.

J Biol Chem 2010 Feb 29;285(8):5327-37. Epub 2009 Dec 29.

Department of Biochemistry and Molecular Genetics, University of Illinois, Chicago, Illinois 60607, USA.

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http://dx.doi.org/10.1074/jbc.M109.078840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820761PMC
February 2010

Fission yeast Tel1(ATM) and Rad3(ATR) promote telomere protection and telomerase recruitment.

PLoS Genet 2009 Aug 28;5(8):e1000622. Epub 2009 Aug 28.

Department of Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, Illinois, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1000622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2726628PMC
August 2009