Lydiana Avila

Lydiana Avila

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Lydiana Avila

Lydiana Avila

Publications by authors named "Lydiana Avila"

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De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.

Authors:
Michael D Kessler Douglas P Loesch James A Perry Nancy L Heard-Costa Daniel Taliun Brian E Cade Heming Wang Michelle Daya John Ziniti Soma Datta Juan C Celedón Manuel E Soto-Quiros Lydiana Avila Scott T Weiss Kathleen Barnes Susan S Redline Ramachandran S Vasan Andrew D Johnson Rasika A Mathias Ryan Hernandez James G Wilson Deborah A Nickerson Goncalo Abecasis Sharon R Browning Sebastian Zöllner Jeffrey R O'Connell Braxton D Mitchell Timothy D O'Connor

Proc Natl Acad Sci U S A 2020 Jan 21. Epub 2020 Jan 21.

Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201;

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http://dx.doi.org/10.1073/pnas.1902766117DOI Listing
January 2020

Whole Genome Sequencing Identifies CRISPLD2 as a Lung Function Gene in Children With Asthma.

Authors:
Priyadarshini Kachroo Julian Hecker Bo L Chawes Tarunveer S Ahluwalia Michael H Cho Dandi Qiao Rachel S Kelly Su H Chu Yamini V Virkud Mengna Huang Kathleen C Barnes Esteban G Burchard Celeste Eng Donglei Hu Juan C Celedón Michelle Daya Albert M Levin Hongsheng Gui L Keoki Williams Erick Forno Angel C Y Mak Lydiana Avila Manuel E Soto-Quiros Michelle M Cloutier Edna Acosta-Pérez Glorisa Canino Klaus Bønnelykke Hans Bisgaard Benjamin A Raby Christoph Lange Scott T Weiss Jessica A Lasky-Su

Chest 2019 Dec 23;156(6):1068-1079. Epub 2019 Sep 23.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2019.08.2202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6904857PMC
December 2019

Pharmacometabolomics of Bronchodilator Response in Asthma and the Role of Age-Metabolite Interactions.

Authors:
Rachel S Kelly Joanne E Sordillo Sharon M Lutz Lydiana Avila Manuel Soto-Quiros Juan C Celedón Michael J McGeachie Amber Dahlin Kelan Tantisira Mengna Huang Clary B Clish Scott T Weiss Jessica Lasky-Su Ann Chen Wu

Metabolites 2019 Sep 7;9(9). Epub 2019 Sep 7.

PRecisiOn Medicine Translational Research (PROMoTeR) Center, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA.

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http://dx.doi.org/10.3390/metabo9090179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780678PMC
September 2019

Epigenetic age acceleration is associated with allergy and asthma in children in Project Viva.

Authors:
Cheng Peng Andres Cardenas Sheryl L Rifas-Shiman Marie-France Hivert Diane R Gold Thomas A Platts-Mills Xihong Lin Emily Oken Lydiana Avila Juan C Celedón Scott T Weiss Andrea A Baccarelli Augusto A Litonjua Dawn L DeMeo

J Allergy Clin Immunol 2019 Jun 6;143(6):2263-2270.e14. Epub 2019 Feb 6.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2019.01.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556426PMC
June 2019

Novel eosinophilic gene expression networks associated with IgE in two distinct asthma populations.

Authors:
Yamini V Virkud Rachel S Kelly Damien C Croteau-Chonka Juan C Celedón Amber Dahlin Lydiana Avila Benjamin A Raby Scott T Weiss Jessica A Lasky-Su

Clin Exp Allergy 2018 12 21;48(12):1654-1664. Epub 2018 Nov 21.

Channing Division of Network Medicine, Department of Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1111/cea.13249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659730PMC
December 2018

A Genome-Wide Association Study in Hispanics/Latinos Identifies Novel Signals for Lung Function. The Hispanic Community Health Study/Study of Latinos.

Authors:
Kristin M Burkart Tamar Sofer Stephanie J London Ani Manichaikul Fernando P Hartwig Qi Yan María Soler Artigas Lydiana Avila Wei Chen Sonia Davis Thomas Alejandro A Diaz Ian P Hall Bernardo L Horta Robert C Kaplan Cathy C Laurie Ana M Menezes Jean V Morrison Elizabeth C Oelsner Deepa Rastogi Stephen S Rich Manuel Soto-Quiros Adrienne M Stilp Martin D Tobin Louise V Wain Juan C Celedón R Graham Barr

Am J Respir Crit Care Med 2018 07;198(2):208-219

1 Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York.

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http://dx.doi.org/10.1164/rccm.201707-1493OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058984PMC
July 2018

Genome-wide interaction study of dust mite allergen on lung function in children with asthma.

Authors:
Erick Forno Joanne Sordillo John Brehm Wei Chen Takis Benos Qi Yan Lydiana Avila Manuel Soto-Quirós Michelle M Cloutier Angel Colón-Semidey Maria Alvarez Edna Acosta-Pérez Scott T Weiss Augusto A Litonjua Glorisa Canino Juan C Celedón

J Allergy Clin Immunol 2017 Oct 4;140(4):996-1003.e7. Epub 2017 Feb 4.

Division of Pediatric Pulmonary Medicine, Allergy, and Immunology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pa; University of Pittsburgh School of Medicine, Pittsburgh, Pa. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.12.967DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544591PMC
October 2017

Genome-wide expression profiles identify potential targets for gene-environment interactions in asthma severity.

Authors:
Joanne E Sordillo Roxanne Kelly Supinda Bunyavanich Michael McGeachie Weiliang Qiu Damien C Croteau-Chonka Manuel Soto-Quiros Lydiana Avila Juan C Celedón John M Brehm Scott T Weiss Diane R Gold Augusto A Litonjua

J Allergy Clin Immunol 2015 Oct 24;136(4):885-92.e2. Epub 2015 Apr 24.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2015.02.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4763940PMC
October 2015

Asthma in Latin America.

Authors:
Erick Forno Mudita Gogna Alfonso Cepeda Anahi Yañez Dirceu Solé Philip Cooper Lydiana Avila Manuel Soto-Quiros Jose A Castro-Rodriguez Juan C Celedón

Thorax 2015 Sep 23;70(9):898-905. Epub 2015 Jun 23.

Division of Pediatric Pulmonary Medicine, Allergy, and Immunology, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1136/thoraxjnl-2015-207199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4593416PMC
September 2015

A Genome-Wide Association Study of Post-bronchodilator Lung Function in Children with Asthma.

Authors:
John M Brehm Sze Man Tse Damien C Croteau-Chonka Erick Forno Augusto A Litonjua Benjamin A Raby Wei Chen Qi Yan Nadia Boutaoui Edna Acosta-Pérez Lydiana Avila Scott T Weiss Manuel Soto-Quiros Michelle M Cloutier Donglei Hu Maria Pino-Yanes Sally E Wenzel Melissa L Spear Jay K Kolls Esteban G Burchard Glorisa Canino Juan C Celedón

Am J Respir Crit Care Med 2015 Sep;192(5):634-7

1 University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1164/rccm.201501-0047LEDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595689PMC
September 2015

Stress and Bronchodilator Response in Children with Asthma.

Authors:
John M Brehm Sima K Ramratnam Sze Man Tse Damien C Croteau-Chonka Maria Pino-Yanes Christian Rosas-Salazar Augusto A Litonjua Benjamin A Raby Nadia Boutaoui Yueh-Ying Han Wei Chen Erick Forno Anna L Marsland Nicole R Nugent Celeste Eng Angel Colón-Semidey María Alvarez Edna Acosta-Pérez Melissa L Spear Fernando D Martinez Lydiana Avila Scott T Weiss Manuel Soto-Quiros Carole Ober Dan L Nicolae Kathleen C Barnes Robert F Lemanske Robert C Strunk Andrew Liu Stephanie J London Frank Gilliland Patrick Sleiman Michael March Hakon Hakonarson Qing Ling Duan Jay K Kolls Gregory K Fritz Donglei Hu Negar Fani Jennifer S Stevens Lynn M Almli Esteban G Burchard Jaemin Shin Elizabeth L McQuaid Kerry Ressler Glorisa Canino Juan C Celedón

Am J Respir Crit Care Med 2015 Jul;192(1):47-56

1 Division of Pulmonary Medicine, Allergy and Immunology, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, and.

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http://www.atsjournals.org/doi/10.1164/rccm.201501-0037OC
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http://dx.doi.org/10.1164/rccm.201501-0037OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4511425PMC
July 2015

A genome-wide association study of chronic obstructive pulmonary disease in Hispanics.

Authors:
Wei Chen John M Brehm Ani Manichaikul Michael H Cho Nadia Boutaoui Qi Yan Kristin M Burkart Paul L Enright Jerome I Rotter Hans Petersen Shuguang Leng Ma'en Obeidat Yohan Bossé Corry-Anke Brandsma Ke Hao Stephen S Rich Rhea Powell Lydiana Avila Manuel Soto-Quiros Edwin K Silverman Yohannes Tesfaigzi R Graham Barr Juan C Celedón

Ann Am Thorac Soc 2015 Mar;12(3):340-8

1 Division of Pulmonary Medicine, Allergy, and Immunology, Children's Hospital of Pittsburgh of the University of Pittsburgh Medical Center, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1513/AnnalsATS.201408-380OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418314PMC
March 2015

A genome-wide survey of CD4(+) lymphocyte regulatory genetic variants identifies novel asthma genes.

Authors:
Sunita Sharma Xiaobo Zhou Derek M Thibault Blanca E Himes Andy Liu Stanley J Szefler Robert Strunk Mario Castro Nadia N Hansel Gregory B Diette Becky M Vonakis N Franklin Adkinson Lydiana Avila Manuel Soto-Quiros Albino Barraza-Villareal Robert F Lemanske Julian Solway Jerry Krishnan Steven R White Chris Cheadle Alan E Berger Jinshui Fan Meher Preethi Boorgula Dan Nicolae Frank Gilliland Kathleen Barnes Stephanie J London Fernando Martinez Carole Ober Juan C Celedón Vincent J Carey Scott T Weiss Benjamin A Raby

J Allergy Clin Immunol 2014 Nov 13;134(5):1153-62. Epub 2014 Jun 13.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, and Harvard Medical School, Boston, Mass; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2014.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253878PMC
November 2014

Native American ancestry, lung function, and COPD in Costa Ricans.

Authors:
Wei Chen John M Brehm Nadia Boutaoui Manuel Soto-Quiros Lydiana Avila Bartolome R Celli Shannon Bruse Yohannes Tesfaigzi Juan C Celedón

Chest 2014 Apr;145(4):704-710

Division of Pulmonary Medicine, Allergy and Immunology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.

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http://dx.doi.org/10.1378/chest.13-1308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971968PMC
April 2014

Trends in hospitalizations and mortality from asthma in Costa Rica over a 12- to 15-year period.

Authors:
Manuel Soto-Martínez Lydiana Avila Natalia Soto Albin Chaves Juan C Celedón Manuel E Soto-Quiros

J Allergy Clin Immunol Pract 2014 Jan-Feb;2(1):85-90. Epub 2013 Nov 12.

Division of Pediatric Pulmonology, Hospital Nacional de Niños, San José, Costa Rica; Department of Pediatrics, Hospital Nacional de Niños, San José, Costa Rica. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2013.09.010DOI Listing
April 2014

Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans.

Authors:
Rachel A Myers Blanca E Himes Christopher R Gignoux James J Yang W James Gauderman Cristina Rebordosa Jianming Xie Dara G Torgerson Albert M Levin James Baurley Penelope E Graves Rasika A Mathias Isabelle Romieu Lindsey A Roth David Conti Lydiana Avila Celeste Eng Hita Vora Michael A LeNoir Manuel Soto-Quiros Jinghua Liu Juan C Celedón Joshua M Galanter Harold J Farber Rajesh Kumar Pedro C Avila Kelley Meade Denise Serebrisky Shannon Thyne William Rodriguez-Cintron Jose R Rodriguez-Santana Luisa N Borrell Robert F Lemanske Eugene R Bleecker Deborah A Meyers Stephanie J London Kathleen C Barnes Benjamin A Raby Fernando D Martinez Frank D Gilliland L Keoki Williams Esteban G Burchard Scott T Weiss Dan L Nicolae Carole Ober

J Allergy Clin Immunol 2012 Dec 4;130(6):1294-301. Epub 2012 Oct 4.

Department of Human Genetics, University of Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.jaci.2012.07.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666859PMC
December 2012

Genome-wide association analysis of circulating vitamin D levels in children with asthma.

Authors:
Jessica Lasky-Su Nancy Lange John M Brehm Amy Damask Manuel Soto-Quiros Lydiana Avila Juan C Celedón Glorisa Canino Michelle M Cloutier Bruce W Hollis Scott T Weiss Augusto A Litonjua

Hum Genet 2012 Sep 7;131(9):1495-505. Epub 2012 Jun 7.

Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1007/s00439-012-1185-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648789PMC
September 2012

High titers of IgE antibody to dust mite allergen and risk for wheezing among asthmatic children infected with rhinovirus.

Authors:
Manuel Soto-Quiros Lydiana Avila Thomas A E Platts-Mills John F Hunt Dean D Erdman Holliday Carper Deborah D Murphy Silvia Odio Hayley R James James T Patrie William Hunt Ashli K O'Rourke Michael D Davis John W Steinke Xiaoyan Lu Joshua Kennedy Peter W Heymann

J Allergy Clin Immunol 2012 Jun 4;129(6):1499-1505.e5. Epub 2012 May 4.

Hospital Nacional de Niños, San José, Costa Rica.

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http://dx.doi.org/10.1016/j.jaci.2012.03.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792652PMC
June 2012

Genome-wide association study reveals class I MHC-restricted T cell-associated molecule gene (CRTAM) variants interact with vitamin D levels to affect asthma exacerbations.

Authors:
Rose Du Augusto A Litonjua Kelan G Tantisira Jessica Lasky-Su Shamil R Sunyaev Barbara J Klanderman Juan C Celedón Lydiana Avila Manuel E Soto-Quiros Scott T Weiss

J Allergy Clin Immunol 2012 Feb 1;129(2):368-73, 373.e1-5. Epub 2011 Nov 1.

Channing Laboratory, Brigham and Women's Hospital, Boston, Mass 02115, USA.

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http://dx.doi.org/10.1016/j.jaci.2011.09.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360942PMC
February 2012

Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease.

Authors:
John M Brehm Koichi Hagiwara Yohannes Tesfaigzi Shannon Bruse Thomas J Mariani Soumyaroop Bhattacharya Nadia Boutaoui John P Ziniti Manuel E Soto-Quiros Lydiana Avila Michael H Cho Blanca Himes Augusto A Litonjua Francine Jacobson Per Bakke Amund Gulsvik Wayne H Anderson David A Lomas Erick Forno Soma Datta Edwin K Silverman Juan C Celedón

Thorax 2011 Dec 15;66(12):1085-90. Epub 2011 Sep 15.

Division of Pediatric Pulmonary Medicine, Allergy and Immunology, Children's Hospital of Pittsburgh of UPMC, 4401 Penn Avenue, Pittsburgh, PA 15224, USA.

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http://dx.doi.org/10.1136/thoraxjnl-2011-200017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348619PMC
December 2011

Association of SERPINE2 with asthma.

Authors:
Blanca E Himes Barbara Klanderman John Ziniti Jody Senter-Sylvia Manuel E Soto-Quiros Lydiana Avila Juan C Celedón Christoph Lange Thomas J Mariani Jessica Lasky-Su Craig P Hersh Benjamin A Raby Edwin K Silverman Scott T Weiss Dawn L DeMeo

Chest 2011 Sep 24;140(3):667-674. Epub 2011 Mar 24.

Channing Laboratory, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1378/chest.10-2973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3168857PMC
September 2011

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

Authors:
Dara G Torgerson Elizabeth J Ampleford Grace Y Chiu W James Gauderman Christopher R Gignoux Penelope E Graves Blanca E Himes Albert M Levin Rasika A Mathias Dana B Hancock James W Baurley Celeste Eng Debra A Stern Juan C Celedón Nicholas Rafaels Daniel Capurso David V Conti Lindsey A Roth Manuel Soto-Quiros Alkis Togias Xingnan Li Rachel A Myers Isabelle Romieu David J Van Den Berg Donglei Hu Nadia N Hansel Ryan D Hernandez Elliott Israel Muhammad T Salam Joshua Galanter Pedro C Avila Lydiana Avila Jose R Rodriquez-Santana Rocio Chapela William Rodriguez-Cintron Gregory B Diette N Franklin Adkinson Rebekah A Abel Kevin D Ross Min Shi Mezbah U Faruque Georgia M Dunston Harold R Watson Vito J Mantese Serpil C Ezurum Liming Liang Ingo Ruczinski Jean G Ford Scott Huntsman Kian Fan Chung Hita Vora Xia Li William J Calhoun Mario Castro Juan J Sienra-Monge Blanca del Rio-Navarro Klaus A Deichmann Andrea Heinzmann Sally E Wenzel William W Busse James E Gern Robert F Lemanske Terri H Beaty Eugene R Bleecker Benjamin A Raby Deborah A Meyers Stephanie J London Frank D Gilliland Esteban G Burchard Fernando D Martinez Scott T Weiss L Keoki Williams Kathleen C Barnes Carole Ober Dan L Nicolae

Nat Genet 2011 Jul 31;43(9):887-92. Epub 2011 Jul 31.

Department of Human Genetics, University of Chicago, Chicago, Illinois, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445408PMC
http://dx.doi.org/10.1038/ng.888DOI Listing
July 2011

Comprehensive genetic assessment of a functional TLR9 promoter polymorphism: no replicable association with asthma or asthma-related phenotypes.

Authors:
Nancy E Lange Xiaobo Zhou Jessica Lasky-Su Blanca E Himes Ross Lazarus Manuel Soto-Quirós Lydiana Avila Juan C Celedón Catherine M Hawrylowicz Benjamin A Raby Augusto A Litonjua

BMC Med Genet 2011 Feb 15;12:26. Epub 2011 Feb 15.

Channing Laboratory, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1186/1471-2350-12-26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048492PMC
February 2011

Thymic stromal lymphopoietin (TSLP) is associated with allergic rhinitis in children with asthma.

Authors:
Supinda Bunyavanich Erik Melen Jemma B Wilk Mark Granada Manuel E Soto-Quiros Lydiana Avila Jessica Lasky-Su Gary M Hunninghake Magnus Wickman Göran Pershagen George T O'Connor Scott T Weiss Juan C Celedón

Clin Mol Allergy 2011 Jan 18;9. Epub 2011 Jan 18.

Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1186/1476-7961-9-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032752PMC
January 2011

Risk factors and predictive clinical scores for asthma exacerbations in childhood.

Authors:
Erick Forno Anne Fuhlbrigge Manuel E Soto-Quirós Lydiana Avila Benjamin A Raby John Brehm Jody M Sylvia Scott T Weiss Juan C Celedón

Chest 2010 Nov 14;138(5):1156-65. Epub 2010 May 14.

Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.

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http://pediatrics.aappublications.org/content/128/Supplement
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http://linkinghub.elsevier.com/retrieve/pii/S001236921060593
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http://dx.doi.org/10.1378/chest.09-2426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2972623PMC
November 2010

Asthma-susceptibility variants identified using probands in case-control and family-based analyses.

Authors:
Blanca E Himes Jessica Lasky-Su Ann C Wu Jemma B Wilk Gary M Hunninghake Barbara Klanderman Amy J Murphy Ross Lazarus Manuel E Soto-Quiros Lydiana Avila Juan C Celedón Christoph Lange George T O'Connor Benjamin A Raby Edwin K Silverman Scott T Weiss

BMC Med Genet 2010 Aug 10;11:122. Epub 2010 Aug 10.

Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, USA.

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http://www.biomedcentral.com/content/pdf/1471-2350-11-122.pd
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http://www.biomedcentral.com/1471-2350/11/122
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http://dx.doi.org/10.1186/1471-2350-11-122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2927535PMC
August 2010

A role for Wnt signaling genes in the pathogenesis of impaired lung function in asthma.

Authors:
Sunita Sharma Kelan Tantisira Vincent Carey Amy J Murphy Jessica Lasky-Su Juan C Celedón Ross Lazarus Barbara Klanderman Angela Rogers Manuel Soto-Quirós Lydiana Avila Thomas Mariani Roger Gaedigk Stephen Leeder John Torday David Warburton Benjamin Raby Scott T Weiss

Am J Respir Crit Care Med 2010 Feb 19;181(4):328-36. Epub 2009 Nov 19.

Channing Laboratory, Center for Genomic Medicine, 181 Longwood Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1164/rccm.200907-1009OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2822972PMC
February 2010

MMP12, lung function, and COPD in high-risk populations.

Authors:
Gary M Hunninghake Michael H Cho Yohannes Tesfaigzi Manuel E Soto-Quiros Lydiana Avila Jessica Lasky-Su Chris Stidley Erik Melén Cilla Söderhäll Jenny Hallberg Inger Kull Juha Kere Magnus Svartengren Göran Pershagen Magnus Wickman Christoph Lange Dawn L Demeo Craig P Hersh Barbara J Klanderman Benjamin A Raby David Sparrow Steven D Shapiro Edwin K Silverman Augusto A Litonjua Scott T Weiss Juan C Celedón

N Engl J Med 2009 Dec 16;361(27):2599-608. Epub 2009 Dec 16.

Channing Laboratory and Center for Genomic Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1056/NEJMoa0904006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904064PMC
December 2009

Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease.

Authors:
Dominique J Verlaan Soizik Berlivet Gary M Hunninghake Anne-Marie Madore Mathieu Larivière Sanny Moussette Elin Grundberg Tony Kwan Manon Ouimet Bing Ge Rose Hoberman Marcin Swiatek Joana Dias Kevin C L Lam Vonda Koka Eef Harmsen Manuel Soto-Quiros Lydiana Avila Juan C Celedón Scott T Weiss Ken Dewar Daniel Sinnett Catherine Laprise Benjamin A Raby Tomi Pastinen Anna K Naumova

Am J Hum Genet 2009 Sep;85(3):377-93

McGill University and Genome Quebec Innovation Centre, Quebec, Canada.

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http://dx.doi.org/10.1016/j.ajhg.2009.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771592PMC
September 2009

PRKCA: a positional candidate gene for body mass index and asthma.

Authors:
Amy Murphy Kelan G Tantisira Manuel E Soto-Quirós Lydiana Avila Barbara J Klanderman Stephen Lake Scott T Weiss Juan C Celedón

Am J Hum Genet 2009 Jul 2;85(1):87-96. Epub 2009 Jul 2.

Channing Laboratory, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.ajhg.2009.06.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706964PMC
July 2009

Serum vitamin D levels and markers of severity of childhood asthma in Costa Rica.

Authors:
John M Brehm Juan C Celedón Manuel E Soto-Quiros Lydiana Avila Gary M Hunninghake Erick Forno Daniel Laskey Jody S Sylvia Bruce W Hollis Scott T Weiss Augusto A Litonjua

Am J Respir Crit Care Med 2009 May 29;179(9):765-71. Epub 2009 Jan 29.

Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1164/rccm.200808-1361OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675563PMC
May 2009

Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.

Authors:
Blanca E Himes Gary M Hunninghake James W Baurley Nicholas M Rafaels Patrick Sleiman David P Strachan Jemma B Wilk Saffron A G Willis-Owen Barbara Klanderman Jessica Lasky-Su Ross Lazarus Amy J Murphy Manuel E Soto-Quiros Lydiana Avila Terri Beaty Rasika A Mathias Ingo Ruczinski Kathleen C Barnes Juan C Celedón William O C Cookson W James Gauderman Frank D Gilliland Hakon Hakonarson Christoph Lange Miriam F Moffatt George T O'Connor Benjamin A Raby Edwin K Silverman Scott T Weiss

Am J Hum Genet 2009 May 7;84(5):581-93. Epub 2009 May 7.

Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, 02138, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S000292970900148
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681010PMC
http://dx.doi.org/10.1016/j.ajhg.2009.04.006DOI Listing
May 2009

Variants in TGFB1, dust mite exposure, and disease severity in children with asthma.

Authors:
Sunita Sharma Benjamin A Raby Gary M Hunninghake Manuel Soto-Quirós Lydiana Avila Amy J Murphy Jessica Lasky-Su Barbara J Klanderman Jody S Sylvia Scott T Weiss Juan C Celedón

Am J Respir Crit Care Med 2009 Mar 18;179(5):356-62. Epub 2008 Dec 18.

Channing Laboratory, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1164/rccm.200808-1268OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648908PMC
March 2009

Dust mite exposure modifies the effect of functional IL10 polymorphisms on allergy and asthma exacerbations.

Authors:
Gary M Hunninghake Manuel E Soto-Quirós Jessica Lasky-Su Lydiana Avila Ngoc P Ly Catherine Liang Barbara J Klanderman Benjamin A Raby Diane R Gold Scott T Weiss Juan C Celedón

J Allergy Clin Immunol 2008 Jul 28;122(1):93-8, 98.e1-5. Epub 2008 Apr 28.

Channing Laboratory, Brigham and Women's Hospital, Boston, Mass 02115, USA.

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http://dx.doi.org/10.1016/j.jaci.2008.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124308PMC
July 2008

Polymorphisms in IL12A and cockroach allergy in children with asthma.

Authors:
Michael Pistiner Gary M Hunninghake Manuel E Soto-Quiros Lydiana Avila Amy Murphy Jessica Lasky-Su Brooke Schuemann Barbara J Klanderman Benjamin A Raby Juan C Celedón

Clin Mol Allergy 2008 Jul 31;6. Epub 2008 Jul 31.

Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.

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http://clinicalmolecularallergy.biomedcentral.com/articles/1
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http://dx.doi.org/10.1186/1476-7961-6-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2525650PMC
July 2008

Sex-stratified linkage analysis identifies a female-specific locus for IgE to cockroach in Costa Ricans.

Authors:
Gary M Hunninghake Jessica Lasky-Su Manuel E Soto-Quirós Lydiana Avila Catherine Liang Stephen L Lake Thomas J Hudson Mitzi Spesny Eduardo Fournier Jody S Sylvia Nelson B Freimer Barbara J Klanderman Benjamin A Raby Juan C Celedón

Am J Respir Crit Care Med 2008 Apr 31;177(8):830-6. Epub 2008 Jan 31.

Channing Laboratory, 181 Longwood Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1164/rccm.200711-1697OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2292826PMC
April 2008

On the replication of genetic associations: timing can be everything!

Authors:
Jessica Lasky-Su Helen N Lyon Valur Emilsson Iris M Heid Cliona Molony Benjamin A Raby Ross Lazarus Barbara Klanderman Manuel E Soto-Quiros Lydiana Avila Edwin K Silverman Gudmar Thorleifsson Unnur Thorsteinsdottir Florian Kronenberg Caren Vollmert Thomas Illig Caroline S Fox Daniel Levy Nan Laird Xiao Ding Matt B McQueen Johannah Butler Kristin Ardlie Constantina Papoutsakis George Dedoussis Christopher J O'Donnell H-Erich Wichmann Juan C Celedón Eric Schadt Joel Hirschhorn Scott T Weiss Kari Stefansson Christoph Lange

Am J Hum Genet 2008 Apr;82(4):849-58

SUNY Upstate Medical University, Syracuse, NY 13210, USA.

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http://dx.doi.org/10.1016/j.ajhg.2008.01.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2427263PMC
April 2008

Paternal asthma, mold exposure, and increased airway responsiveness among children with asthma in Costa Rica.

Authors:
Ngoc P Ly Manuel E Soto-Quirós Lydiana Avila Gary M Hunninghake Benjamin A Raby Daniel Laskey Jody S Sylvia Juan C Celedón

Chest 2008 Jan 7;133(1):107-14. Epub 2007 Nov 7.

Channing Laboratory, 181 Longwood Ave, Boston, MA 02115, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00123692154896
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http://dx.doi.org/10.1378/chest.07-2130DOI Listing
January 2008

Comprehensive testing of positionally cloned asthma genes in two populations.

Authors:
Craig P Hersh Benjamin A Raby Manuel E Soto-Quirós Amy J Murphy Lydiana Avila Jessica Lasky-Su Jody S Sylvia Barbara J Klanderman Christoph Lange Scott T Weiss Juan C Celedón

Am J Respir Crit Care Med 2007 Nov 16;176(9):849-57. Epub 2007 Aug 16.

Channing Laboratory and Center for Genomic Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1164/rccm.200704-592OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2048676PMC
November 2007

Polymorphisms in IL13, total IgE, eosinophilia, and asthma exacerbations in childhood.

Authors:
Gary M Hunninghake Manuel E Soto-Quirós Lydiana Avila Jessica Su Amy Murphy Dawn L Demeo Ngoc P Ly Catherine Liang Jody S Sylvia Barbara J Klanderman Christoph Lange Benjamin A Raby Edwin K Silverman Juan C Celedón

J Allergy Clin Immunol 2007 Jul 11;120(1):84-90. Epub 2007 Jun 11.

Channing Laboratory; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.jaci.2007.04.032DOI Listing
July 2007

The association of a SNP upstream of INSIG2 with body mass index is reproduced in several but not all cohorts.

Authors:
Helen N Lyon Valur Emilsson Anke Hinney Iris M Heid Jessica Lasky-Su Xiaofeng Zhu Gudmar Thorleifsson Steinunn Gunnarsdottir G Bragi Walters Unnur Thorsteinsdottir Augustine Kong Jeffrey Gulcher Thuy Trang Nguyen André Scherag Arne Pfeufer Thomas Meitinger Günter Brönner Winfried Rief Manuel E Soto-Quiros Lydiana Avila Barbara Klanderman Benjamin A Raby Edwin K Silverman Scott T Weiss Nan Laird Xiao Ding Leif Groop Tiinamaija Tuomi Bo Isomaa Kristina Bengtsson Johannah L Butler Richard S Cooper Caroline S Fox Christopher J O'Donnell Caren Vollmert Juan C Celedón H Erich Wichmann Johannes Hebebrand Kari Stefansson Christoph Lange Joel N Hirschhorn

PLoS Genet 2007 Apr 7;3(4):e61. Epub 2007 Mar 7.

Program in Genomics, Divisions of Genetics and Endocrinology, Children's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1371/journal.pgen.0030061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1857727PMC
April 2007

Genome-wide linkage analysis of pulmonary function in families of children with asthma in Costa Rica.

Authors:
Craig P Hersh Manuel E Soto-Quirós Lydiana Avila Stephen L Lake Catherine Liang Eduardo Fournier Mitzi Spesny Jody S Sylvia Ross Lazarus Thomas Hudson Andrei Verner Barbara J Klanderman Nelson B Freimer Edwin K Silverman Juan C Celedón

Thorax 2007 Mar 10;62(3):224-30. Epub 2006 Nov 10.

Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1136/thx.2006.067934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2117166PMC
March 2007

Sensitization to Ascaris lumbricoides and severity of childhood asthma in Costa Rica.

Authors:
Gary M Hunninghake Manuel E Soto-Quiros Lydiana Avila Ngoc P Ly Catherine Liang Jody S Sylvia Barbara J Klanderman Edwin K Silverman Juan C Celedón

J Allergy Clin Immunol 2007 Mar;119(3):654-61

Channing Laboratory, Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1016/j.jaci.2006.12.609DOI Listing
March 2007

Sex-specific linkage to total serum immunoglobulin E in families of children with asthma in Costa Rica.

Authors:
Benjamin A Raby Manuel E Soto-Quiros Lydiana Avila Stephen L Lake Amy Murphy Catherine Liang Eduardo Fournier Mitzi Spesny Jody S Sylvia Andrei Verner Thomas J Hudson Barbara J Klanderman Nelson B Freimer Edwin K Silverman Juan C Celedón

Hum Mol Genet 2007 Feb 1;16(3):243-53. Epub 2006 Dec 1.

Channing Laboratory and Respiratory Disorders Program, Department of Medicine, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA 02115, USA.

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http://academic.oup.com/hmg/article/16/3/243/610703/Sexspeci
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http://dx.doi.org/10.1093/hmg/ddl447DOI Listing
February 2007

Significant linkage to airway responsiveness on chromosome 12q24 in families of children with asthma in Costa Rica.

Authors:
Juan C Celedón Manuel E Soto-Quiros Lydiana Avila Stephen L Lake Catherine Liang Eduardo Fournier Mitzi Spesny Craig P Hersh Jody S Sylvia Thomas J Hudson Andrei Verner Barbara J Klanderman Nelson B Freimer Edwin K Silverman Scott T Weiss

Hum Genet 2007 Jan 26;120(5):691-9. Epub 2006 Sep 26.

Channing Laboratory, Department of Medicine and Respiratory Disorders Program, Brigham and Women's Hospital, 181 Longwood Avenue, Boston, MA 02115, USA.

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http://link.springer.com/10.1007/s00439-006-0255-5
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http://dx.doi.org/10.1007/s00439-006-0255-5DOI Listing
January 2007

Asthma, current wheezing, and tobacco use among adolescents and young adults in Costa Rica.

Authors:
Lydiana Avila Manuel E Soto-Martínez Manuel E Soto-Quirós Juan C Celedón

J Asthma 2005 Sep;42(7):543-7

Division of Pediatric Pulmonology, Hospital Nacional de Niños, San José, Costa Rica.

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http://dx.doi.org/10.1080/02770900500214791DOI Listing
September 2005