Lydia Teboul

Lydia Teboul

UNVERIFIED PROFILE

Are you Lydia Teboul?   Register this Author

Register author
Lydia Teboul

Lydia Teboul

Publications by authors named "Lydia Teboul"

Are you Lydia Teboul?   Register this Author

45Publications

1487Reads

21Profile Views

Targeted Mutations in the Mouse via Embryonic Stem Cells.

Methods Mol Biol 2020 ;2066:59-82

The Centre for Phenogenomics (TCP), Toronto, ON, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-9837-1_5DOI Listing
January 2020

Male mice lacking ADAMTS-16 are fertile but exhibit testes of reduced weight.

Sci Rep 2019 Nov 20;9(1):17195. Epub 2019 Nov 20.

Mammalian Genetics Unit, Medical Research Council, Harwell Institute, Oxfordshire, OX11 0RD, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-019-53900-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868159PMC
November 2019

When all is not lost: considering genetic compensation in laboratory animals.

Lab Anim (NY) 2019 10;48(10):282-284

The Mary Lyon Centre, Medical Research Council Harwell Institute, Oxon, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41684-019-0397-4DOI Listing
October 2019

Microhomologies are prevalent at Cas9-induced larger deletions.

Nucleic Acids Res 2019 08;47(14):7402-7417

MRC Molecular Hematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DS, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkz459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6698657PMC
August 2019

Characterisation and use of a functional Gadd45g bacterial artificial chromosome.

Sci Rep 2018 11 23;8(1):17318. Epub 2018 Nov 23.

Mammalian Genetics Unit, MRC Harwell Institute, Oxfordshire, OX11 0RD, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-018-35458-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251886PMC
November 2018

CRISPR-Cas9-Mediated Mutagenesis: Mind the Gap?

CRISPR J 2018 08;1:263-264

2 Mammalian Genetics Unit, Medical Research Council Harwell Institute, Oxfordshire, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/crispr.2018.29027.greDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636871PMC
August 2018

Response to "Unexpected mutations after CRISPR-Cas9 editing in vivo".

Nat Methods 2018 04 30;15(4):235-236. Epub 2018 Mar 30.

IMPC Cas9 Working Group and the IMPC Steering Committee and executive director of the IMPC (www.mousephenotype.org).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nmeth.4559DOI Listing
April 2018

FTO demethylase activity is essential for normal bone growth and bone mineralization in mice.

Biochim Biophys Acta Mol Basis Dis 2018 Mar 2;1864(3):843-850. Epub 2017 Dec 2.

Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbadis.2017.11.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798602PMC
March 2018

Corrigendum: High-throughput discovery of novel developmental phenotypes.

Nature 2017 11 8;551(7680):398. Epub 2017 Nov 8.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature24643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849394PMC
November 2017

Introduction to Mammalian Genome Special Issue: Genome Editing.

Mamm Genome 2017 08;28(7-8):235-236

The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00335-017-9708-5DOI Listing
August 2017

Phenotyping first-generation genome editing mutants: a new standard?

Mamm Genome 2017 08 29;28(7-8):377-382. Epub 2017 Jul 29.

Mammalian Genetics Unit, MRC Harwell Institute, Harwell Science Campus, Didcot, Oxfordshire, UK.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00335-017-9711-x
Publisher Site
http://dx.doi.org/10.1007/s00335-017-9711-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569115PMC
August 2017

Analysing the outcome of CRISPR-aided genome editing in embryos: Screening, genotyping and quality control.

Methods 2017 05 28;121-122:68-76. Epub 2017 Mar 28.

The Mary Lyon Centre, MRC Harwell Institute, Didcot, Oxon OX11 0RD, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ymeth.2017.03.016DOI Listing
May 2017

N-ethyl-N-nitrosourea-Induced Adaptor Protein 2 Sigma Subunit 1 () Mutations Establish Loss-of-Function Mice.

JBMR Plus 2017 May;1(1):3-15

Academic Endocrine Unit, Radcliffe Department of Medicine, University of Oxford, Oxford Centre for Diabetes, Endocrinology, and Metabolism (OCDEM), Churchill Hospital, Oxford, UK.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/jbm4.10001
Publisher Site
http://dx.doi.org/10.1002/jbm4.10001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824975PMC
May 2017

High-throughput discovery of novel developmental phenotypes.

Nature 2016 09 14;537(7621):508-514. Epub 2016 Sep 14.

The Jackson Laboratory, Bar Harbor, Maine 04609, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature19356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5295821PMC
September 2016

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.

Authors:
Martin Hrabě de Angelis George Nicholson Mohammed Selloum Jacqui White Hugh Morgan Ramiro Ramirez-Solis Tania Sorg Sara Wells Helmut Fuchs Martin Fray David J Adams Niels C Adams Thure Adler Antonio Aguilar-Pimentel Dalila Ali-Hadji Gregory Amann Philippe André Sarah Atkins Aurelie Auburtin Abdel Ayadi Julien Becker Lore Becker Elodie Bedu Raffi Bekeredjian Marie-Christine Birling Andrew Blake Joanna Bottomley Mike Bowl Véronique Brault Dirk H Busch James N Bussell Julia Calzada-Wack Heather Cater Marie-France Champy Philippe Charles Claire Chevalier Francesco Chiani Gemma F Codner Roy Combe Roger Cox Emilie Dalloneau André Dierich Armida Di Fenza Brendan Doe Arnaud Duchon Oliver Eickelberg Chris T Esapa Lahcen El Fertak Tanja Feigel Irina Emelyanova Jeanne Estabel Jack Favor Ann Flenniken Alessia Gambadoro Lilian Garrett Hilary Gates Anna-Karin Gerdin George Gkoutos Simon Greenaway Lisa Glasl Patrice Goetz Isabelle Goncalves Da Cruz Alexander Götz Jochen Graw Alain Guimond Wolfgang Hans Geoff Hicks Sabine M Hölter Heinz Höfler John M Hancock Robert Hoehndorf Tertius Hough Richard Houghton Anja Hurt Boris Ivandic Hughes Jacobs Sylvie Jacquot Nora Jones Natasha A Karp Hugo A Katus Sharon Kitchen Tanja Klein-Rodewald Martin Klingenspor Thomas Klopstock Valerie Lalanne Sophie Leblanc Christoph Lengger Elise le Marchand Tonia Ludwig Aline Lux Colin McKerlie Holger Maier Jean-Louis Mandel Susan Marschall Manuel Mark David G Melvin Hamid Meziane Kateryna Micklich Christophe Mittelhauser Laurent Monassier David Moulaert Stéphanie Muller Beatrix Naton Frauke Neff Patrick M Nolan Lauryl Mj Nutter Markus Ollert Guillaume Pavlovic Natalia S Pellegata Emilie Peter Benoit Petit-Demoulière Amanda Pickard Christine Podrini Paul Potter Laurent Pouilly Oliver Puk David Richardson Stephane Rousseau Leticia Quintanilla-Fend Mohamed M Quwailid Ildiko Racz Birgit Rathkolb Fabrice Riet Janet Rossant Michel Roux Jan Rozman Ed Ryder Jennifer Salisbury Luis Santos Karl-Heinz Schäble Evelyn Schiller Anja Schrewe Holger Schulz Ralf Steinkamp Michelle Simon Michelle Stewart Claudia Stöger Tobias Stöger Minxuan Sun David Sunter Lydia Teboul Isabelle Tilly Glauco P Tocchini-Valentini Monica Tost Irina Treise Laurent Vasseur Emilie Velot Daniela Vogt-Weisenhorn Christelle Wagner Alison Walling Bruno Weber Olivia Wendling Henrik Westerberg Monja Willershäuser Eckhard Wolf Anne Wolter Joe Wood Wolfgang Wurst Ali Önder Yildirim Ramona Zeh Andreas Zimmer Annemarie Zimprich Chris Holmes Karen P Steel Yann Herault Valérie Gailus-Durner Ann-Marie Mallon Steve Dm Brown

Nat Genet 2015 Sep 27;47(9):969-978. Epub 2015 Jul 27.

MRC Harwell, Medical Research Council, Harwell, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564951PMC
September 2015

The mammalian gene function resource: the International Knockout Mouse Consortium.

Mamm Genome 2012 Oct 12;23(9-10):580-6. Epub 2012 Sep 12.

The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00335-012-9422-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463800PMC
October 2012

Uncoupling antisense-mediated silencing and DNA methylation in the imprinted Gnas cluster.

PLoS Genet 2011 Mar 24;7(3):e1001347. Epub 2011 Mar 24.

Medical Research Council Mammalian Genetics Unit, Harwell Science and Innovation Campus, Harwell, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1001347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3063750PMC
March 2011

Overexpression of Fto leads to increased food intake and results in obesity.

Nat Genet 2010 Dec 14;42(12):1086-92. Epub 2010 Nov 14.

MRC Harwell, Metabolism and Inflammation, Harwell Science and Innovation Campus, Harwell, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018646PMC
December 2010

Transgene design and delivery into the mouse genome: keys to success.

Authors:
Lydia Teboul

Methods Mol Biol 2009 ;561:105-10

Mary Lyon Centre, Medical Research Council, Harwell, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-60327-019-9_7DOI Listing
September 2009

Overexpression transgenesis in mouse: pronuclear injection.

Methods Mol Biol 2009 ;561:111-26

Mary Lyon Centre, Medical Research Council, Harwell, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-60327-019-9_8DOI Listing
September 2009

NAADP mobilizes calcium from acidic organelles through two-pore channels.

Nature 2009 May 22;459(7246):596-600. Epub 2009 Apr 22.

Centre for Integrative Physiology, College of Medicine and Veterinary Medicine, University of Edinburgh, Hugh Robson Building, Edinburgh EH8 9XD, Scotland, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature08030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761823PMC
May 2009

p27kip1 independently promotes neuronal differentiation and migration in the cerebral cortex.

Genes Dev 2006 Jun 16;20(11):1511-24. Epub 2006 May 16.

Division of Molecular Neurobiology, National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.377106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1475763PMC
June 2006

The initial somitic phase of Myf5 expression requires neither Shh signaling nor Gli regulation.

Genes Dev 2003 Dec;17(23):2870-4

Section of Gene Function and Regulation, The Institute of Cancer Research, Chester Beatty Laboratories, London SW3 6JB, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gad.1117603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC289147PMC
December 2003

The early epaxial enhancer is essential for the initial expression of the skeletal muscle determination gene Myf5 but not for subsequent, multiple phases of somitic myogenesis.

Development 2002 Oct;129(19):4571-80

Division of Eukaryotic Molecular Genetics, MRC National Institute for Medical Research, The Ridgeway, Mill Hill, London NW7 1AA, UK.

View Article

Download full-text PDF

Source
October 2002