Publications by authors named "Lydia Giménez-Llort"

90 Publications

Digging Signatures in 13-Month-Old 3xTg-AD Mice for Alzheimer's Disease and Its Disruption by Isolation Despite Social Life Since They Were Born.

Front Behav Neurosci 2020 18;14:611384. Epub 2021 Jan 18.

Institut de Neurociències, Universitat Autònoma de Barcelona, Barcelona, Spain.

View Article and Find Full Text PDF
January 2021

Sex-Dependent End-of-Life Mental and Vascular Scenarios for Compensatory Mechanisms in Mice with Normal and AD-Neurodegenerative Aging.

Biomedicines 2021 Jan 24;9(2). Epub 2021 Jan 24.

Department of Psychiatry and Forensic Medicine, School of Medicine, Universitat Autònoma de Barcelona, 08193 Barcelona, Spain.

View Article and Find Full Text PDF
January 2021

Impact of Social Isolation on the Behavioral, Functional Profiles, and Hippocampal Atrophy Asymmetry in Dementia in Times of Coronavirus Pandemic (COVID-19): A Translational Neuroscience Approach.

Front Psychiatry 2020 24;11:572583. Epub 2020 Nov 24.

Department of Psychiatry and Forensic Medicine, School of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.

View Article and Find Full Text PDF
November 2020

PasoDoble, a Proposed Dance/Music for People With Parkinson's Disease and Their Caregivers.

Front Neurol 2020 12;11:567891. Epub 2020 Nov 12.

Department of Psychiatry and Forensic Medicine, School of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.

View Article and Find Full Text PDF
November 2020

IL-6 Trans-Signaling in the Brain Influences the Metabolic Phenotype of the 3xTg-AD Mouse Model of Alzheimer's Disease.

Cells 2020 07 2;9(7). Epub 2020 Jul 2.

Institute of Neurosciences and Department of Cellular Biology, Physiology and Immunology, Faculty of Biosciences, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.

View Article and Find Full Text PDF
July 2020

Foundations and Applications of Logotherapy to Improve Mental Health of Immigrant Populations in the Third Millennium.

Front Psychiatry 2020 3;11:451. Epub 2020 Jun 3.

Department of Psychiatry and Forensic Medicine, School of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.

View Article and Find Full Text PDF
June 2020

The Impact of the PI3K/Akt Signaling Pathway in Anxiety and Working Memory in Young and Middle-Aged PDK1 K465E Knock-In Mice.

Front Behav Neurosci 2020 8;14:61. Epub 2020 May 8.

Institut de Neurociències, Universitat Autònoma de Barcelona, Barcelona, Spain.

View Article and Find Full Text PDF
May 2020

Impact of Chronic Risperidone Use on Behavior and Survival of 3xTg-AD Mice Model of Alzheimer's Disease and Mice With Normal Aging.

Front Pharmacol 2019 24;10:1061. Epub 2019 Sep 24.

Medical Psychology Unit, Department of Psychiatry and Forensic Medicine, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Spain.

View Article and Find Full Text PDF
September 2019

Indexes for flotation and circling, two non-search behaviors in the water maze, sensitive to d-galactose-induced accelerated aging and Alzheimer's disease.

Behav Brain Res 2020 01 11;377:112229. Epub 2019 Sep 11.

Institut de Neurociències, Universitat Autònoma de Barcelona, Barcelona, Spain; Department of Psychiatry and Forensic Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain. Electronic address:

View Article and Find Full Text PDF
January 2020

IL-6 trans-signaling in the brain influences the behavioral and physio-pathological phenotype of the Tg2576 and 3xTgAD mouse models of Alzheimer's disease.

Brain Behav Immun 2019 11 8;82:145-159. Epub 2019 Aug 8.

Institute of Neurosciences and Department of Cellular Biology, Physiology and Immunology, Faculty of Biosciences, Universitat Autònoma de Barcelona, 08193, Spain. Electronic address:

View Article and Find Full Text PDF
November 2019

Short height and poor education increase the risk of dementia in Nigerian type 2 diabetic women.

Alzheimers Dement (Amst) 2019 Dec 9;11:493-499. Epub 2019 Jul 9.

Department of Psychiatry and Forensic Medicine, School of Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain.

View Article and Find Full Text PDF
December 2019

Vibrating Tail, Digging, Body/Face Interaction, and Lack of Barbering: Sex-Dependent Behavioral Signatures of Social Dysfunction in 3xTg-AD Mice as Compared to Mice with Normal Aging.

J Alzheimers Dis 2019 ;69(4):969-977

Department of Psychiatry and Forensic Medicine, Faculty of Medicine, Universitat Autònoma de Barcelona, Cerdanyola del Vallès, Barcelona, Spain.

View Article and Find Full Text PDF
September 2020

Altered slow (<1 Hz) and fast (beta and gamma) neocortical oscillations in the 3xTg-AD mouse model of Alzheimer's disease under anesthesia.

Neurobiol Aging 2019 07 13;79:142-151. Epub 2019 Mar 13.

Systems Neuroscience, IDIBAPS (Institut d'Investigacions Biomèdiques August Pi i Sunyer), Barcelona, Spain; ICREA, Barcelona, Spain. Electronic address:

View Article and Find Full Text PDF
July 2019

Comorbid sensorimotor and emotional profiles in the forced swim test immobility and predictive value of a single assay in very old female mice.

Exp Gerontol 2019 06 14;120:107-112. Epub 2019 Mar 14.

Institute of Neuroscience, Universitat Autònoma de Barcelona, 08193, Cerdanyola del Vallès, Barcelona, Spain; Medical Psychology Unit, Department of Psychiatry and Forensic Medicine, School of Medicine, Campus Bellaterra, Universitat Autònoma de Barcelona, 08193, Cerdanyola del Vallès, Barcelona, Spain. Electronic address:

View Article and Find Full Text PDF
June 2019

Neuroprotective Effects of the Multitarget Agent AVCRI104P3 in Brain of Middle-Aged Mice.

Int J Mol Sci 2018 Sep 4;19(9). Epub 2018 Sep 4.

Neuroscience Institute, Autonomous University of Barcelona, 08193 Barcelona, Spain.

View Article and Find Full Text PDF
September 2018

Sex-dependent co-occurrence of hypoxia and β-amyloid plaques in hippocampus and entorhinal cortex is reversed by long-term treatment with ubiquinol and ascorbic acid in the 3 × Tg-AD mouse model of Alzheimer's disease.

Mol Cell Neurosci 2018 10 25;92:67-81. Epub 2018 Jun 25.

Department of Medical Sciences, Faculty of Medicine, University of Castilla-La Mancha, Spain; Oxidative Stress and Neurodegeneration Group, Regional Centre for Biomedical Research, University of Castilla-La Mancha, Spain. Electronic address:

View Article and Find Full Text PDF
October 2018

Endocannabinoid and Muscarinic Signaling Crosstalk in the 3xTg-AD Mouse Model of Alzheimer's Disease.

J Alzheimers Dis 2018 ;64(1):117-136

Department of Pharmacology, Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), B° Sarriena s/n, Leioa, Spain.

View Article and Find Full Text PDF
June 2019

Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice.

Sci Rep 2018 04 24;8(1):6431. Epub 2018 Apr 24.

Institut de Neurociències, Departament de Bioquímica i Biologia Molecular, Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas (CIBERNED), Universitat Autònoma de Barcelona, Bellaterra, 08193, Spain.

View Article and Find Full Text PDF
April 2018

Distinct phenotypes of spontaneous activity and induction of amphetamine sensitization in inbred Roman high- and low-avoidance rats: Vulnerability and protection.

Neurosci Lett 2018 04 6;673:92-98. Epub 2018 Mar 6.

Department of Molecular Medicine, Karolinska Institutet and Department of Geriatrics, Karolinska University Hospital, Sweden.

View Article and Find Full Text PDF
April 2018

Sexual Dimorphism in the Behavioral Responses and the Immunoendocrine Status in d-Galactose-Induced Aging.

J Gerontol A Biol Sci Med Sci 2018 08;73(9):1147-1157

Translational Behavioral Neuroscience Group, Institute of Neuroscience, Barcelona, Spain.

View Article and Find Full Text PDF
August 2018

Reducing the Levels of Akt Activation by PDK1 Knock-in Mutation Protects Neuronal Cultures against Synthetic Amyloid-Beta Peptides.

Front Aging Neurosci 2017 8;9:435. Epub 2018 Jan 8.

Unitat de Bioquímica de Medicina, Departament de Bioquímica i Biologia Molecular, Institut de Neurociències, Universitat Autònoma de Barcelona, Barcelona, Spain.

View Article and Find Full Text PDF
January 2018

Survival Curves and Behavioral Profiles of Female 3xTg-AD Mice Surviving to 18-Months of Age as Compared to Mice with Normal Aging.

J Alzheimers Dis Rep 2017 Jul 6;1(1):47-57. Epub 2017 Jul 6.

Institut de Neurociències, Universitat Autònoma de Barcelona, Barcelona, Spain.

View Article and Find Full Text PDF
July 2017

Behavioural effects of novel multitarget anticholinesterasic derivatives in Alzheimer's disease.

Behav Pharmacol 2017 04;28(2 and 3-Spec Issue):124-131

aInstitut de Neurociències bDepartment of Psychiatry and Forensic Medicine cDepartment of Pharmacology, Therapeutics and Toxicology, Autonomous University of Barcelona dLaboratory of Pharmaceutical Chemistry (CSIC Associated Unit), Faculty of Pharmacy and Food Sciences eInstitute of Biomedicine (IBUB), University of Barcelona, Barcelona, Spain.

View Article and Find Full Text PDF
April 2017