Publications by authors named "Luke Jostins"

34Publications

Graphical Model Selection for Gaussian Conditional Random Fields in the Presence of Latent Variables.

J Am Stat Assoc 2019 11;114(526):723-734. Epub 2018 Jul 11.

Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK.

View Article

Download full-text PDF

Source
https://www.tandfonline.com/doi/full/10.1080/01621459.2018.1
Publisher Site
http://dx.doi.org/10.1080/01621459.2018.1434531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636895PMC
July 2018

Bayesian meta-analysis across genome-wide association studies of diverse phenotypes.

Genet Epidemiol 2019 07 28;43(5):532-547. Epub 2019 Mar 28.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gepi.22202DOI Listing
July 2019

Genome-wide association study of primary sclerosing cholangitis identifies new risk loci and quantifies the genetic relationship with inflammatory bowel disease.

Nat Genet 2017 Feb 19;49(2):269-273. Epub 2016 Dec 19.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540332PMC
February 2017

Genetic Complexity of Crohn's Disease in Two Large Ashkenazi Jewish Families.

Gastroenterology 2016 10 1;151(4):698-709. Epub 2016 Jul 1.

Division of Medicine, University College London (UCL), London, United Kingdom. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2016.06.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5643259PMC
October 2016

Trinculo: Bayesian and frequentist multinomial logistic regression for genome-wide association studies of multi-category phenotypes.

Bioinformatics 2016 06 11;32(12):1898-900. Epub 2016 Feb 11.

Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, OX3 7BN, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btw075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908321PMC
June 2016

Using genetic prediction from known complex disease Loci to guide the design of next-generation sequencing experiments.

PLoS One 2013 18;8(10):e76328. Epub 2013 Oct 18.

Medical Genomics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom ; Wellcome Trust Centre for Human Genetics, Univeristy of Oxford, Oxford, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0076328PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799779PMC
August 2014

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Authors:
Luke Jostins Stephan Ripke Rinse K Weersma Richard H Duerr Dermot P McGovern Ken Y Hui James C Lee L Philip Schumm Yashoda Sharma Carl A Anderson Jonah Essers Mitja Mitrovic Kaida Ning Isabelle Cleynen Emilie Theatre Sarah L Spain Soumya Raychaudhuri Philippe Goyette Zhi Wei Clara Abraham Jean-Paul Achkar Tariq Ahmad Leila Amininejad Ashwin N Ananthakrishnan Vibeke Andersen Jane M Andrews Leonard Baidoo Tobias Balschun Peter A Bampton Alain Bitton Gabrielle Boucher Stephan Brand Carsten Büning Ariella Cohain Sven Cichon Mauro D'Amato Dirk De Jong Kathy L Devaney Marla Dubinsky Cathryn Edwards David Ellinghaus Lynnette R Ferguson Denis Franchimont Karin Fransen Richard Gearry Michel Georges Christian Gieger Jürgen Glas Talin Haritunians Ailsa Hart Chris Hawkey Matija Hedl Xinli Hu Tom H Karlsen Limas Kupcinskas Subra Kugathasan Anna Latiano Debby Laukens Ian C Lawrance Charlie W Lees Edouard Louis Gillian Mahy John Mansfield Angharad R Morgan Craig Mowat William Newman Orazio Palmieri Cyriel Y Ponsioen Uros Potocnik Natalie J Prescott Miguel Regueiro Jerome I Rotter Richard K Russell Jeremy D Sanderson Miquel Sans Jack Satsangi Stefan Schreiber Lisa A Simms Jurgita Sventoraityte Stephan R Targan Kent D Taylor Mark Tremelling Hein W Verspaget Martine De Vos Cisca Wijmenga David C Wilson Juliane Winkelmann Ramnik J Xavier Sebastian Zeissig Bin Zhang Clarence K Zhang Hongyu Zhao Mark S Silverberg Vito Annese Hakon Hakonarson Steven R Brant Graham Radford-Smith Christopher G Mathew John D Rioux Eric E Schadt Mark J Daly Andre Franke Miles Parkes Severine Vermeire Jeffrey C Barrett Judy H Cho

Nature 2012 Nov;491(7422):119-24

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature11582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491803PMC
November 2012

Dispatches from the functional phase of genome biology.

Authors:
Luke Jostins

Genome Biol 2012 Jun 27;13(6):316. Epub 2012 Jun 27.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/gb-2012-13-6-316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446312PMC
June 2012

Genetic risk prediction in complex disease.

Hum Mol Genet 2011 Oct 25;20(R2):R182-8. Epub 2011 Aug 25.

Statistical and Computational Genetics, Wellcome Trust Sanger Institute, Cambs, UK

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddr378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179379PMC
October 2011

Imputation of low-frequency variants using the HapMap3 benefits from large, diverse reference sets.

Eur J Hum Genet 2011 Jun 2;19(6):662-6. Epub 2011 Mar 2.

Statistical and Computational Genetics, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/ejhg201110
Publisher Site
http://dx.doi.org/10.1038/ejhg.2011.10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110048PMC
June 2011

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.

Nat Genet 2010 Dec;42(12):1118-25

Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel, Kiel, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3299551PMC
December 2010

Reverse engineering a gene network using an asynchronous parallel evolution strategy.

BMC Syst Biol 2010 Mar 2;4:17. Epub 2010 Mar 2.

Laboratory for Development & Evolution, University Museum of Zoology, Department of Zoology, University of Cambridge, Cambridge, CB2 3EJ, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1752-0509-4-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2850326PMC
March 2010

Microindel detection in short-read sequence data.

Bioinformatics 2010 Mar 9;26(6):722-9. Epub 2010 Feb 9.

Institute for Medical Genetics, Charité-Universitätsmedizin Berlin, 13353 Berlin.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btq027DOI Listing
March 2010