Lukasz Japtok

Lukasz Japtok

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Lukasz Japtok

Lukasz Japtok

Publications by authors named "Lukasz Japtok"

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Identification of functional lipid metabolism biomarkers of brown adipose tissue aging.

Mol Metab 2019 Jun 4;24:1-17. Epub 2019 Apr 4.

Department of Adipocyte Development and Nutrition, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany; German Center for Diabetes Research (DZD), München, Neuherberg, Germany; Institute of Nutritional Science, University of Potsdam, Potsdam-Rehbrücke, Nuthetal, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22128778183119
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http://dx.doi.org/10.1016/j.molmet.2019.03.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531832PMC
June 2019

CD40 Enhances Sphingolipids in Orbital Fibroblasts: Potential Role of Sphingosine-1-Phosphate in Inflammatory T-Cell Migration in Graves' Orbitopathy.

Invest Ophthalmol Vis Sci 2018 11;59(13):5391-5397

Molecular Ophthalmology, Department of Ophthalmology, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1167/iovs.18-25466DOI Listing
November 2018

Dietary carbohydrates impair the protective effect of protein restriction against diabetes in NZO mice used as a model of type 2 diabetes.

Diabetologia 2018 06 17;61(6):1459-1469. Epub 2018 Mar 17.

Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Arthur-Scheunert-Allee 114-116, 14558, Nuthetal, Germany.

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http://dx.doi.org/10.1007/s00125-018-4595-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449005PMC
June 2018

Lysophosphatidic Acid Inhibits Insulin Signaling in Primary Rat Hepatocytes via the LPA3 Receptor Subtype and is Increased in Obesity.

Cell Physiol Biochem 2017 1;43(2):445-456. Epub 2017 Sep 1.

Faculty of Mathematics and Natural Science, Institute of Nutritional Science, Department of Toxicology, University of Potsdam, Potsdam, Germany.

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http://dx.doi.org/10.1159/000480470DOI Listing
October 2017

Acid sphingomyelinase mediates murine acute lung injury following transfusion of aged platelets.

Am J Physiol Lung Cell Mol Physiol 2017 05 10;312(5):L625-L637. Epub 2017 Mar 10.

Keenan Research Centre for Biomedical Science, St. Michael's Hospital, Toronto, Ontario, Canada;

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http://dx.doi.org/10.1152/ajplung.00317.2016DOI Listing
May 2017

Inflammatory cells, ceramides, and expression of proteases in perivascular adipose tissue adjacent to human abdominal aortic aneurysms.

J Vasc Surg 2017 04 6;65(4):1171-1179.e1. Epub 2016 Mar 6.

Division of Drug Research, Department of Medical and Health Sciences, Linköping University, Linköping, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jvs.2015.12.056DOI Listing
April 2017

Involvement of Sphingosine 1-Phosphate in Palmitate-Induced Non-Alcoholic Fatty Liver Disease.

Cell Physiol Biochem 2016 23;40(6):1637-1645. Epub 2016 Dec 23.

Faculty of Mathematics and Natural Science, Institute of Nutritional Science, Department of Toxicology, University of Potsdam, Potsdam, Germany.

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http://dx.doi.org/10.1159/000453213DOI Listing
February 2017

Acid Sphingomyelinase Inhibition in Stored Erythrocytes Reduces Transfusion-Associated Lung Inflammation.

Ann Surg 2017 01;265(1):218-226

*Department of Surgery and Institute for Military Medicine, University of Cincinnati, Cincinnati, OH †Department of Toxicology, Institute of Nutritional Science, University of Potsdam, Germany ‡Department of Molecular Biology, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1097/SLA.0000000000001648DOI Listing
January 2017

Inhibition of Acid Sphingomyelinase Allows for Selective Targeting of CD4+ Conventional versus Foxp3+ Regulatory T Cells.

J Immunol 2016 10 16;197(8):3130-3141. Epub 2016 Sep 16.

Institute for Virology and Immunobiology, University of Würzburg, D-97078 Würzburg, Germany;

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http://dx.doi.org/10.4049/jimmunol.1600691DOI Listing
October 2016

A sphingolipid mechanism for behavioral extinction.

J Neurochem 2016 05 15;137(4):589-603. Epub 2016 Mar 15.

Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1111/jnc.13537DOI Listing
May 2016

Hepatocyte exosomes mediate liver repair and regeneration via sphingosine-1-phosphate.

J Hepatol 2016 Jan 5;64(1):60-8. Epub 2015 Aug 5.

Department of Surgery, University of Cincinnati, College of Medicine, Cincinnati, OH 45267, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01688278150053
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http://dx.doi.org/10.1016/j.jhep.2015.07.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843792PMC
January 2016

Inhibition of neutral sphingomyelinase protects mice against systemic tuberculosis.

Front Biosci (Elite Ed) 2016 Jan 1;8:311-25. Epub 2016 Jan 1.

Department of Molecular Biology, University of Duisburg-Essen, Hufelandstrasse 55, 45122 Essen, Germany,

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January 2016

Endothelial sphingosine kinase/SPNS2 axis is critical for vessel-like formation by human mesoangioblasts.

J Mol Med (Berl) 2015 Oct 9;93(10):1145-57. Epub 2015 May 9.

Dipartimento di Scienze Biomediche Sperimentali e Cliniche "Mario Serio", Università di Firenze, Viale G.B. Morgagni 50, 50134, Florence, Italy.

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http://link.springer.com/10.1007/s00109-015-1292-0
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http://dx.doi.org/10.1007/s00109-015-1292-0DOI Listing
October 2015

Decreased plasma levels of the endothelial protective sphingosine-1-phosphate are associated with dengue-induced plasma leakage.

J Infect 2015 Oct 14;71(4):480-7. Epub 2015 Jul 14.

Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1016/j.jinf.2015.06.014DOI Listing
October 2015

Sphingosine 1-phosphate counteracts insulin signaling in pancreatic β-cells via the sphingosine 1-phosphate receptor subtype 2.

FASEB J 2015 Aug 24;29(8):3357-69. Epub 2015 Apr 24.

*Faculty of Mathematics and Natural Science, Institute of Nutritional Science, Department of Toxicology, University of Potsdam, Potsdam, Germany; German Institute of Human Nutrition, Max Rubner Laboratory, Nuthetal, Germany; and Lpath Incorporated, San Diego, California, USA

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http://dx.doi.org/10.1096/fj.14-263194DOI Listing
August 2015

Sphingosine-1-phosphate modulates dendritic cell function: focus on non-migratory effects in vitro and in vivo.

Cell Physiol Biochem 2014 16;34(1):27-44. Epub 2014 Jun 16.

Pharmazentrum Frankfurt/ZAFES, Clinic of the Goethe University, Frankfurt, Germany.

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http://dx.doi.org/10.1159/000362982DOI Listing
February 2015

Divergent role of sphingosine 1-phosphate on insulin resistance.

Cell Physiol Biochem 2014 16;34(1):134-47. Epub 2014 Jun 16.

Faculty of Mathematics and Natural Science, Institute of Nutritional Science, Department of Toxicology, University of Potsdam, Potsdam, Germany.

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http://dx.doi.org/10.1159/000362990DOI Listing
February 2015

CTGF/CCN2 exerts profibrotic action in myoblasts via the up-regulation of sphingosine kinase-1/S1P3 signaling axis: Implications in the action mechanism of TGFβ.

Biochim Biophys Acta 2015 Feb 29;1851(2):194-202. Epub 2014 Nov 29.

Dipartimento di Scienze Biomediche Sperimentali e Cliniche "Mario Serio," Università di Firenze, Viale G.B. Morgagni 50, Firenze 50134, Italy; Istituto Interuniversitario di Miologia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2014.11.011DOI Listing
February 2015

Sphingoid long chain bases prevent lung infection by Pseudomonas aeruginosa.

EMBO Mol Med 2014 Sep;6(9):1205-14

Department of Molecular Biology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany Department of Surgery, University of Cincinnati, Cincinnati, OH, USA

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http://dx.doi.org/10.15252/emmm.201404075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4197866PMC
September 2014

Sphingosine-1-phosphate as signaling molecule in the skin: Relevance in atopic dermatitis.

Allergo J Int 2014;23(2):54-59. Epub 2014 Mar 19.

Toxicology, Faculty of Mathematics and Natural Science, University of Potsdam, Potsdam, Germany ; Department of Toxicology Faculty of Mathematics and Natural Science, University of Potsdam, Arthur-Scheunert-Allee 114-116, 14558 Nuthetal, Germany.

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http://link.springer.com/10.1007/s40629-014-0008-2
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http://dx.doi.org/10.1007/s40629-014-0008-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479432PMC
March 2014

Involvement of sphingosine 1-phosphate in palmitate-induced insulin resistance of hepatocytes via the S1P2 receptor subtype.

Diabetologia 2014 Feb 29;57(2):373-82. Epub 2013 Nov 29.

Faculty of Mathematics and Natural Science, Institute of Nutritional Science, Department of Toxicology, University of Potsdam, Arthur-Scheunert Allee 114-116, 14558, Nuthetal, Potsdam, Germany.

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http://dx.doi.org/10.1007/s00125-013-3123-6DOI Listing
February 2014

Sphingolipids and inflammatory diseases of the skin.

Handb Exp Pharmacol 2013 (216):355-72

Department of Toxicology, University of Potsdam, Nuthetal, Potsdam, Germany.

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http://dx.doi.org/10.1007/978-3-7091-1511-4_18DOI Listing
July 2013

Sphingosine-1-phosphate exhibits anti-proliferative and anti-inflammatory effects in mouse models of psoriasis.

J Dermatol Sci 2013 Jul 6;71(1):29-36. Epub 2013 Apr 6.

Department of Pharmacology, Toxicology and Pharmacy, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.

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http://dx.doi.org/10.1016/j.jdermsci.2013.03.006DOI Listing
July 2013

Sphingosine 1-phosphate modulates antigen capture by murine Langerhans cells via the S1P2 receptor subtype.

PLoS One 2012 8;7(11):e49427. Epub 2012 Nov 8.

Faculty of Mathematics and Natural Science, Department of Toxicology, Institute of Nutritional Science, University of Potsdam, Potsdam, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0049427PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493526PMC
June 2013

Sphingosine 1-phosphate mediates chemotaxis of human primary fibroblasts via the S1P-receptor subtypes S1P₁ and S1P₃ and Smad-signalling.

Cytoskeleton (Hoboken) 2010 Dec 10;67(12):773-83. Epub 2010 Nov 10.

Institute of Pharmacy, Free University of Berlin and Physics Department, Phillips University of Marburg, Germany.

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http://dx.doi.org/10.1002/cm.20486DOI Listing
December 2010

The role of sphingosine-1-phosphate receptor modulators in the prevention of transplant rejection and autoimmune diseases.

Curr Opin Investig Drugs 2009 Nov;10(11):1183-94

Freie Universität Berlin, Institute of Pharmacy, Pharmacology and Toxicology, Königin-Luise-Strause 2+4, D-14195 Berlin, Germany.

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November 2009