Publications by authors named "Luis Ríos"

77 Publications

Sexuality and prevention among men who have sex with men in the contexts of the AIDS and COVID-19 pandemics.

Cien Saude Colet 2021 May;26(5):1853-1862

Laboratório de Estudos da Sexualidade Humana do Departamento de Psicologia da Universidade Federal de Pernambuco. Av. Acadêmico Helio Ramos, CFCH, 7º andar. Cidade Universitária. 50670-901 Recife PE Brasil.

This essay reflects on sexual practices and prevention in the contexts of the AIDS and COVID-19 pandemics. It analyses data collected between July and October 2020 through participant observation, as part of an ethnographic research project on HIV vulnerability and prevention among men who have sex with men in the Metropolitan Region of Recife, state of Pernambuco (PE), Brazil. The results point to the relevance of physical appearance and the affective bond between partners in engendering emotions that mediate coping with the risk of infection during both pandemics. It indicates the need to incorporate those communicational dimensions into informational materials to make them more effective.
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http://dx.doi.org/10.1590/1413-81232021265.00482021DOI Listing
May 2021

Safety of a Protective Funnel in Primary Breast Augmentation: A Retrospective Analysis of 380 Multicenter Cases in the United States.

Aesthet Surg J 2021 Apr 17. Epub 2021 Apr 17.

Background: Protective funnels devices are commonly used to deliver implants in primary breast augmentation (BA) yet there is a paucity of evidence-based data describing their safety in the literature.

Objectives: The purpose of the study was to assess the safety of protective funnels in primary BA within the first 30-days postoperatively.

Methods: This multi-center, Level 3 study retrospectively reviewed the surgical records of 380 consecutive patients (760 breasts) who underwent primary BA by nine board-certified plastic surgeons using the iNPLANT Funnel (Proximate Concepts LLC, Allendale, NJ, USA) for implant delivery between November 2019 and December 2020. Data was collected pertaining to demographics, implant information, surgery details, and postoperative complications.

Results: The mean patient age was 33 years and 76% patients had a BMI < 25. Of this cohort, 11.4% were smokers, 0.8% had diabetes, and 83% were ASA class 1. All patients received smooth implants with a median volume of 375cc. A total of 8 (2.1%) complications were reported including: 3 hematomas (0.79%), 1 seroma (0.26%) and 1 superficial infection (0.26%). No patient required explantation. We identified ASA class, BMI, surgery duration, and implant size as potential risk factors.

Conclusions: The data suggest that use of protective funnels, such as the iNPLANT Funnel, in primary BA are a safe option when used according to the manufacturer's IFU. Its use led to a low infection rate (0.26%) and a complication rate (2.1%) consistent with the average reported in the literature (2%-2.5%). 1 Implications for clinical practice are encouraging and future research will include a prospective analysis with a larger case series and potentially a control group.
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http://dx.doi.org/10.1093/asj/sjab198DOI Listing
April 2021

Extra-Adrenal Retroperitoneal Myelolipoma Resected by Laparoscopy in an Asymptomatic Patient.

Case Rep Surg 2021 13;2021:8849194. Epub 2021 Mar 13.

Department of Urology at Hospital do Servidor Público Estadual (HSPE), The Medical Sciences Course, Faculty of Health Sciences, Pontifical Catholic University of São Paulo, Sorocaba, SP, Brazil.

Myelolipomas are rare benign neoplasms that commonly develop in the adrenal glands. Less frequently, they can affect other organs such as the liver, stomach, liver, lung, and retroperitoneum. It affects more women, with an average age of around 61 years. Histologically, they are composed of mature adipose tissue and hematopoietic cells. With the evolution of immunohistochemistry, there are characteristics that can differentiate from malignant tumors such as liposarcomas. Its treatment remains based on surgical resection and long-term outpatient follow-up.
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http://dx.doi.org/10.1155/2021/8849194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7984877PMC
March 2021

Commentary on: Aesthetic Surgery Research Funding: Where Does It Come From and to Whom Does It Go?

Authors:
Luis Rios

Aesthet Surg J 2021 Feb 27. Epub 2021 Feb 27.

Department of Surgery, University of Texas Rio Grande Valley School of Medicine, Edinburg, TX, USA.

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http://dx.doi.org/10.1093/asj/sjab006DOI Listing
February 2021

Reliability of Throwing Velocity during Non-specific and Specific Handball Throwing Tests.

Int J Sports Med 2020 Oct 30. Epub 2020 Oct 30.

Department of Physical Education and Sport, Universidad de Granada, Granada.

Throwing velocity is one of the most important factors for scoring goals in handball. This study aimed to identify the type of throw and procedure for selecting the final test outcome that provide throwing velocity with the greatest reliability. Fifteen experienced handball players and 33 non-experienced participants were tested in two sessions. Each session consisted of 4 trials of 3 different throwing tests (unspecific, 7-meters, and 3-steps). The maximum value of 4 trials, average value of 4 trials, and average value of the 3 best trials were considered. Throwing velocity was highly reliable (coefficient of variation [CV]≤3.3%, intraclass correlation coefficient≥0.89) with the exception of the unspecific throw for the non-experienced group (CV≥5.9%, intraclass correlation coefficient≤0.56). The 3-steps throw (CV=1.7%) was more reliable than the 7-meters throw (CV=2.1%) (CV=1.19) and unspecific throw (CV = 3.8%) (CV=2.18), the 3 procedures provided a comparable reliability (CV range=2.4-2.6%; CV≤1.07), and the experienced group (CV=1.0%) presented a higher reliability than the non-experienced group (CV=4.0%) (CV=3.83). These results support the 3-steps throw to maximise the reliability of throwing velocity performance.
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http://dx.doi.org/10.1055/a-1273-8630DOI Listing
October 2020

Prevalence of self-reported complications associated with intermittent catheterization in wheelchair athletes with spinal cord injury.

Spinal Cord 2020 Oct 13. Epub 2020 Oct 13.

International Collaboration on Repair Discoveries (ICORD), Faculty of Medicine, University of British Columbia (UBC), Vancouver, British Columbia (BC), Canada.

Study Design: Cross-sectional study.

Objectives: To identify the prevalence of complications associated with intermittent catheterization in wheelchair athletes with spinal cord injury (SCI).

Setting: International and national sporting events.

Methods: A total 130 competitive wheelchair athletes living with SCI completed a self-reported questionnaire during international or national sporting events. The questionnaire collected information regarding demographics, injury characteristics, method of bladder emptying, and complications related to intermittent catheterization.

Results: Overall, 84% (109/130) of wheelchair athletes used intermittent catheterization. Within this group, 77% of athletes (84/109) experienced at least one complication associated with intermittent catheterization. Twenty-seven percent (29/109) sustained urethral injuries and 63% (69/109) had at least one episode of urinary tract infection during the last 12 months. Almost one-fourth of male athletes (22/95, 23%) had a history of inflammation / infection of genital organs associated with intermittent catheterization.

Conclusions: Here we report a high prevalence of self-reported complications associated with intermittent catheterization in wheelchair athletes with SCI. Considering their potential impact on lower urinary tract function, athletic performance, and health, further studies are needed to assess the role of preventative strategies to reduce complications related to intermittent catheterization in wheelchair athletes with SCI.

Sponsorship: Coloplast Brazil and Instituto Lado a Lado pela Vida (a nongovernmental, nonprofit organization based in São Paulo) and Wellspect provided funding for this study.
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http://dx.doi.org/10.1038/s41393-020-00565-6DOI Listing
October 2020

Comment on 'Krapina atlases suggest a high prevalence of anatomical variations in the first cervical vertebra of Neanderthals'.

J Anat 2020 12 31;237(6):1185-1188. Epub 2020 Jul 31.

Department of Archaeology, Centre for Forensic Research, Simon Fraser University, Burnaby, BC, Canada.

A review of the observation of an anterior cleft on the atlas of a Neanderthal from Krapina.
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http://dx.doi.org/10.1111/joa.13268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7704232PMC
December 2020

Bladder lesions as incidental findings during transurethral resection of the prostate: prevalence, diagnosis, and pathological findings.

World J Urol 2020 Jul 30. Epub 2020 Jul 30.

Institute for the Medical Care of Civil Servants, São Paulo, Brazil.

Purpose: The purpose of this study was to determine the prevalence of bladder lesions diagnosed during transurethral resection of the prostate (TURP), to identify the associated risk factors, and to correlate the macroscopic descriptions with the pathological findings.

Methods: This was a single-center retrospective case series conducted at a hospital in the city of São Paulo, Brazil. We reviewed the medical and surgical records of patients who underwent TURP between January 2012 and December 2017.

Results: The final sample comprised 513 patients, with a mean age of 70.8 years. Bladder lesions were identified during TURP in 109 (21.2%) of the patients, and 90 of those lesions were submitted for pathological examination. The most common macroscopic finding was bullous edema, which was seen in 57 (63.3%) of the 90 lesions examined. The pathological analysis revealed chronic cystitis in 61 lesions (67.8%) and malignant lesions in 16 (17.8%). Of the 57 lesions described as bullous edema, 5 (8.8%) were found to be malignant.

Conclusions: Alterations in the bladder mucosa appear to be more common among elderly patients who use an indwelling urinary catheter for a prolonged period and among patients with recurrent urinary tract infections. In addition, the risk of a bladder lesion being malignant is apparently higher in current and former smokers than in never smokers. Our findings suggest that at-risk patients should undergo biopsy or resection of incidental bladder lesions even if those lesions seem to be benign, due to the low level of agreement between the visual analysis and the pathological examination.
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http://dx.doi.org/10.1007/s00345-020-03389-4DOI Listing
July 2020

Kinetic modeling of the alkaline deproteinization of Nile-tilapia skin for the production of collagen.

Heliyon 2020 May 4;6(5):e03854. Epub 2020 May 4.

Grupo de Nutrición y Tecnología de Alimentos, Facultad de Ciencias Farmacéuticas y Alimentarias, Universidad de Antioquia U de A, Calle 70 # 52-21, Medellín, Colombia.

A new phenomenological model, based on a second order dissolution kinetics, was developed for the alkaline removal of non-collagenous protein (NCP) from the skin of Nile tilapia (SNT). This model allows estimating the liquid concentration of NCP in terms of temperature, skin size, NaOH concentration and time. This model was fitted with 135 experiments averaging a R of 0.99. The root-mean-square deviation and the mean-absolute-percentage error of the model were 0.0041 and 3.15%, respectively. The Arrhenius-activation energy was 15-122 kJ mol. Multi-objective optimization led to the highest NCP extraction (NCPE) of 24.3% and to the lowest loss of collagen (LC) of 1.3%, with R coefficients of 0.98 and 0.92, respectively. Ultimately, SNT deproteinized under optimal conditions was subjected to acid extraction and purification. FTIR and SEM analyses indicated that the product was a Type I collagen that could be used in the pharmaceutical industry.
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http://dx.doi.org/10.1016/j.heliyon.2020.e03854DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210409PMC
May 2020

Improvement in Brazilian Butt Lift (BBL) Safety With the Current Recommendations from ASERF, ASAPS, and ISAPS.

Aesthet Surg J 2020 07;40(8):864-870

Department of Surgery, University of Texas Rio Grande Valley School of Medicine, Edinburg, TX.

Background: In 2017, the ASERF Gluteal Fat Grafting Task Force reported gluteal fat grafting to be a high-risk procedure and recommended specific surgical techniques to decrease the risk of pulmonary fat embolism (PFE).

Objectives: The aim of this study was to determine whether ASAPS and ISAPS members were aware of the 2017 recommendations, what their current surgical techniques were, whether they had changed their techniques based on the 2017 recommendations, and whether the incidence of PFEs had changed since the recommendations were published.

Methods: An anonymous web-based survey was conducted among members of ASAPS and ISAPS. It included the questions from the 2017 survey, as well as questions about awareness of the Task Force recommendations and subsequent change in surgical techniques.

Results: In the 2 years following the publication of the recommendations, the incidence of any PFE was 1 in 2492 compared with 1 in 1030 reported in 2017 (P = 0.02). Trends indicated a decreased mortality rate from 1 in 3448 in 2017 to 1 in 14,952 in 2019. Ninety-four percent of respondents were aware of the recommendations. Only 0.8% of surgeons in the current survey reported injecting in deep muscle, compared with 13.1% in 2017 (P < 0.01). Compared with 4.1% in 2017, 29.8% of respondents in our survey reported that they only injected with cannulas ≥4.1 mm (P < 0.01). Only 4% of respondents reported angling the cannula down in the current survey, compared with 27.2% in 2017 (P < 0.01).

Conclusions: It appears that members were aware of the 2017 recommendations. There was a significant decrease in recent PFE and trends showed a change to safer techniques and an improvement in safety of the procedure.
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http://dx.doi.org/10.1093/asj/sjaa098DOI Listing
July 2020

Plasticity in the growth of body segments in relation to height-for-age and maternal education in Guatemala.

Am J Hum Biol 2020 07 19;32(4):e23376. Epub 2019 Dec 19.

School of Sport, Exercise & Health Sciences, Loughborough University, Loughborough, UK.

Objectives: Plasticity in the growth of body segments between populations has been researched in relation to migration, temporal change and high-altitude studies. We study the within population variation in body segments, thus controlling for some of the environmental and genetic differences that could be at play in between populations studies. We test a version of the thrifty phenotype hypothesis, where the growth of head-trunk and hand are prioritized due to their functional significance over height and leg growth.

Materials And Methods: A total of 3913 Guatemalan, rural, semi-urban and urban, Maya and Ladino children 6 to 15 years old were studied. Height, sitting height, leg length, and metacarpal length were studied in relation to three proxies for living conditions: height- and leg length-for-age, and maternal education. Estimation statistics and null hypothesis significance testing were used to analyze the data.

Results: Metatarsal length and sitting height values were higher than height and leg length respectively. Relative metacarpal length was conserved across height-for-age groups. Females were less affected than males for metacarpal length and sitting height, but more affected for leg length.

Conclusion: Our results agree with the thrifty phenotype hypothesis, where metacarpal and sitting height growth would be prioritized over height and leg length due to greater functional significance.
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http://dx.doi.org/10.1002/ajhb.23376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7507214PMC
July 2020

Dopamine D1 and muscarinic acetylcholine receptors in dorsal striatum are required for high speed running.

Neurosci Res 2020 Jul 5;156:50-57. Epub 2019 Dec 5.

Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamada-oka, Suita, Osaka, 565-0871, Japan. Electronic address:

Dopamine (DA) signaling in the basal ganglia plays important roles in motor control. Motor deficiencies were previously reported in dopamine receptor D1 (D1R) and D2 (D2R) knockout mice. While these results indicate the involvement of DA receptors in motor execution, the null knockout (KO) mouse lacks the specificity necessary to determine when and where in the brain D1R and D2R function in motor execution. To address these questions, we restricted the loss of function temporally and spatially by using D1R conditional knockdown (cKD) mice and mice injected with antagonists against DA receptors directly into the dorsal striatum. In addition, we address the DA and acetylcholine (ACh) balance hypothesis by using antagonists against ACh receptors. We tested the motor ability of the mice with a newly devised task named the accelerating step-wheel. In this task, the maximum running speed was measured in a situation where the wheel rotation speed was gradually accelerated in one trial. We found significant decreases in the maximum running speed of D1R cKD mice and the mice injected with the antagonist against D1R or muscarinic ACh receptor. These results indicated that D1R and muscarinic ACh receptor in the dorsal striatum play pivotal roles in the execution of walking/running.
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http://dx.doi.org/10.1016/j.neures.2019.12.001DOI Listing
July 2020

Synaptic Specializations of Melanopsin-Retinal Ganglion Cells in Multiple Brain Regions Revealed by Genetic Label for Light and Electron Microscopy.

Cell Rep 2019 10;29(3):628-644.e6

Salk Institute for Biological Studies, La Jolla, CA, USA. Electronic address:

The form and synaptic fine structure of melanopsin-expressing retinal ganglion cells, also called intrinsically photosensitive retinal ganglion cells (ipRGCs), were determined using a new membrane-targeted version of a genetic probe for correlated light and electron microscopy (CLEM). ipRGCs project to multiple brain regions, and because the method labels the entire neuron, it was possible to analyze nerve terminals in multiple retinorecipient brain regions, including the suprachiasmatic nucleus (SCN), olivary pretectal nucleus (OPN), and subregions of the lateral geniculate. Although ipRGCs provide the only direct retinal input to the OPN and SCN, ipRGC terminal arbors and boutons were found to be remarkably different in each target region. A network of dendro-dendritic chemical synapses (DDCSs) was also revealed in the SCN, with ipRGC axon terminals preferentially synapsing on the DDCS-linked cells. The methods developed to enable this analysis should propel other CLEM studies of long-distance brain circuits at high resolution.
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http://dx.doi.org/10.1016/j.celrep.2019.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7045601PMC
October 2019

Hydroxytyrosol inhibits MAO isoforms and prevents neurotoxicity inducible by MPP+ invivo.

Front Biosci (Schol Ed) 2020 01 1;12:25-37. Epub 2020 Jan 1.

Laboratorio de Neuroproteccion, Facultad de Farmacia, Universidad Autonoma del Estado de Morelos, Av. Universidad 1001, Col. Chamilpa, Cuernavaca, Morelos, Mexico,

Parkinson's disease is considered to be due to an increase in the catabolism of dopamine by the action of monoamine oxidase (MAO) enzymes which leads to an increase in reactive oxygen species (ROS) and loss of dopaminergic neurons. Here, in a model of neurotoxicity inducible by 1-methyl-4-phenylpyridinium (MPP+), we tested the effect of hydroxytyrosol (HTy), a potent antioxidant, on generation of ROS. Five minutes after a single intravenous administration of 1.5 mg/Kg of Hty, Wistar rats received an intrastriatal micro-injection of 10 micrograms of MPP+ while control animals received saline solution. Six days later, all animals were treated with apomorphine (1 mg/Kg), subcutaneously and ipsilateral rotations were assessed within an hour. Then, the rats were sacrificed, striatal tissues were removed and their catecholamines and MAO-A and B activities were quantitated. Pretreatment with HTy significantly diminished the number of ipsilateral rotations. This recovery correlated with significant preservation of striatal dopamine and significant inhibition of of the MAO activity. These results are consistent with the inhibitory effect of HTy on the MAO isoforms and form a basis for the neuroprotective mechanism of this phenylpropanoid in MPP+ induced Parkinson's disease.
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January 2020

Scaling of stem diameter and height allometry in 14 neotropical palm species of different forest strata.

Oecologia 2019 Aug 2;190(4):757-767. Epub 2019 Jul 2.

Escuela de Biología, Universidad de Costa Rica, San Pedro, San José, 11501-2060, Costa Rica.

Tropical palms reach tree-like heights without a vascular cambium through sustained cell expansion and lignification of primary tissues, but only a fraction of palms have been explored in their allometric relationships. Here, our main question was to determine how palms depart from the traditional mechanical models developed for trees and how they approach the theoretical buckling limit. We analyzed the stem allometry of 1603 palms of 14 species from different strata at 10 sites in Costa Rica and Peru. We measured their fit to the stress, elastic, and geometric similarity models, and their position relative to the maximum theoretical buckling limit calculated for trees. We evaluated the slope of the linear and logarithmic regressions between stem diameter and height using logarithmic least squares, and standardized major axis regression (SMA), expecting segregation according to canopy position and geographic location. Seventeen out of 19 statistically significant models had SMA slopes > 1, and 11 had SMA slopes ≥ 2, departing from traditional mechanical models developed for trees. Many species varied their allometry relative to geographic location. Canopy palms showed the highest regression fit but had less steep slopes than understory and subcanopy species. Subcanopy and understory species were more underbuilt than canopy palms, increasing height faster than diameter. Some of the tallest canopy palms surpassed the maximum buckling limit whereas subcanopy and understory species were consistently below the buckling limit of record-size trees. Palm stem allometry changed in response to environmental conditions.
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http://dx.doi.org/10.1007/s00442-019-04452-7DOI Listing
August 2019

Disparities in Height and Urban Social Stratification in the First Half of the 20th Century in Madrid (Spain).

Int J Environ Res Public Health 2019 06 10;16(11). Epub 2019 Jun 10.

Department of Applied Economics, Faculty of Economics and Business, Murcia University, 30100 Murcia, Spain.

Adult height is the most commonly used biological indicator to evaluate material and emotional conditions in which people grew up, allowing the analysis of secular trends associated with socio-economic change as well as of social inequalities among human populations. There is a lack of studies on both aspects regarding urban populations. Our study evaluates the secular trends and the disparities in height of conscripts born between 1915 and 1953 and called-up at the age of 21 between 1936 and 1969, living in districts with low versus middle and high socio-economic conditions, in the city of Madrid, Spain. We test the hypothesis that urban spatial segregation and social stratification was associated with significant differences in height. Results show that height increased significantly during the analysed period, both among conscripts living in the middle- and upper-class districts (5.85 cm) and in the lower-class districts (6.75 cm). The positive secular trend in height among conscripts from middle- and upper-class districts was sustained throughout the period, but the trend in height among the lower class fluctuated according to social, political, and economic events. Our findings support previous research that adult height is influenced strongly by the family living conditions during infancy and by community effects acting during childhood and adolescence.
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http://dx.doi.org/10.3390/ijerph16112048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603878PMC
June 2019

[Sexual positions, body styles and HIV risk among men who have sex with men in Recife (Brazil)].

Cien Saude Colet 2019 Mar;24(3):973-982

Departamento de Psicologia, Centro de Filosofia e Ciências Humanas,Universidade Federal de Pernambuco. Av. Acadêmico Helio Ramos CFCH/7º, Cidade Universitária. 50670-901 Recife PE Brasil.

The article presents the results of an ethnographic study of the gay community in Recife (PE), conducted via participant observation and interviews. It seeks to understand sexual risk conduct among men who have sex with men (MSM) and HIV, focusing on the significance of sexual positions during anal-receptive intercourse (ARI) and anal-insertive intercourse (AII). Those who practice unprotected ARI are subject to a greater risk of infection than those who practice AII. Those who practice both, ARI and AII, are amplifiers (greater chances of receiving and passing on the virus) in the transmission chains. The text addresses the emic categories related with gender identities - pintosa (female gay), boy (male gay), and cafuçu (MSM and with women, non-gay, male, lower social class) - and with gender identities - active (AII), passive (ARI), and versatile (AII and ARI) - in the ways they result in sexual positions and produce sexual attraction. Masculine men are the most sexually desirable. Boys tend to relate with boys, and pintosas with cafuçus. There is a significant number of versatiles, which increases the collective risk within the gay community. By means of the relations between pintosas and cafuçus, there is increased danger for the virus to circulate more among the gay community and society in general.
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http://dx.doi.org/10.1590/1413-81232018243.34092016DOI Listing
March 2019

Bilateral internal thoracic artery versus single internal thoracic artery: a meta-analysis of propensity score-matched observational studies.

Interact Cardiovasc Thorac Surg 2019 Mar 8. Epub 2019 Mar 8.

Cardiac Surgery Department, Hospital Universitario Dr. Negrín, Las Palmas de Gran Canaria, Spain.

The lack of benefit in terms of mid-term survival and the increase in the risk of sternal wound complications published in a recent randomized controlled trial have raised concerns about the use of bilateral internal thoracic artery (BITA) in myocardial revascularization surgery. For this reason, we decided to explore the current evidence available on the subject by carrying out a meta-analysis of propensity score-matched studies comparing BITA versus single internal thoracic artery (SITA). PubMed, EMBASE and Google Scholar were searched for propensity score-matched studies comparing BITA versus SITA. The generic inverse variance method was used to compute the combined hazard ratio (HR) of long-term mortality. The DerSimonian and Laird method was used to compute the combined risk ratio of 30-day mortality, deep sternal wound infection and reoperation for bleeding. Forty-five BITA versus SITA matched populations were included. Meta-analysis showed a significant benefit in terms of long-term survival in favour of the BITA group [HR 0.78; 95% confidence interval (CI) 0.71-0.86]. These results were consistent with those obtained by a pooled analysis of the matched populations comprising patients with diabetes (HR 0.65; 95% CI 0.43-0.99). When compared with the use of SITA plus radial artery, BITA did not show any significant benefit in terms of long-term survival (HR 0.86; 95% CI 0.69-1.07). No differences between BITA and SITA groups were detected in terms of 30-day mortality or in terms of reoperation for bleeding. Compared with the SITA group, patients in the BITA group had a significantly higher risk of deep sternal wound infection (risk ratio 1.66; 95% CI 1.41-1.95) even when the pooled analysis was limited to matched populations in which BITA was harvested according to the skeletonization technique (risk ratio 1.37; 95% CI 1.04-1.79). The use of BITA provided a long-term survival benefit compared with the use of SITA at the expense of a higher risk of sternal deep wound infection. The long-term survival advantage of BITA is undetectable when compared with SITA plus radial artery.
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http://dx.doi.org/10.1093/icvts/ivz037DOI Listing
March 2019

Evidenced-Based Approach to Abdominoplasty Update.

Aesthet Surg J 2019 05;39(6):628-642

Department of Plastic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA.

The following publication was compiled as an evidence-based update for plastic surgeons performing abdominoplasty from a review of the published literature on that subject between January 2014 and February 2017. It is an overview of various aspects of abdominoplasty including preoperative patient assessment, variations and advances in both surgical and anesthetic technique, patient safety, and outcomes. It is intended to serve as an adjunct to previously published evidence-based reviews of abdominoplasty.
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http://dx.doi.org/10.1093/asj/sjy215DOI Listing
May 2019

Evidenced-Based Approach to Abdominoplasty Update.

Aesthet Surg J 2019 05;39(6):628-642

Department of Plastic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA.

The following publication was compiled as an evidence-based update for plastic surgeons performing abdominoplasty from a review of the published literature on that subject between January 2014 and February 2017. It is an overview of various aspects of abdominoplasty including preoperative patient assessment, variations and advances in both surgical and anesthetic technique, patient safety, and outcomes. It is intended to serve as an adjunct to previously published evidence-based reviews of abdominoplasty.
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http://dx.doi.org/10.1093/asj/sjy215DOI Listing
May 2019

[Height cohorts and district of residence in the city of Madrid during the 20th century].

Nutr Hosp 2018 Jun 4;35(Spec No5):83-90. Epub 2018 Jun 4.

.

Objective: in recent decades, an interesting literature has accumulated regarding the biological living standard in Spain at the end of the 19th Century and during the 20th Century. Adult height has been one of the most studied variables, specifically its temporal change at the national and provincial levels, the impact of the Civil War and the subsequent dictatorship, and the differences between urban and rural areas. We want to contribute to this general overview with the presentation of a project about an intra-urban perspective of the city of Madrid.

Methods: We present the stature data of the male population of two Madrid districts, Salamanca and Vallecas, for the period 1936-1986 (year of measurement).

Results: In these years, height increased by 5.58 cm, from 166.40 to 171.98 cm, with significant differences observed between both districts as well as a simultaneous decrease of that difference, for those born in 1915 and 1953 from 3.09 to 1.2 cm. The negative effect of the Civil War and the years of autarky are also observed in this urban sample.

Conclusion: Considering these data together with those available for other demographic and socioeconomic variables, before and after the period studied, we can conclude that the division by districts represents an effective stratification in the biological living standard of the population of the city of Madrid. These results constitute a first intra-urban approximation using height to the debate on inequality and biological living standards in Spain during the 20th Century.
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http://dx.doi.org/10.20960/nh.2089DOI Listing
June 2018

Response to Comment on "The growth pattern of Neandertals, reconstructed from a juvenile skeleton from El Sidrón (Spain)".

Science 2018 03;359(6380)

Department of Cell and Developmental Biology, University College London, London WC1E 6BT, UK.

The comment by DeSilva challenges our suggestion that brain growth of the El Sidrón J1 Neandertal was still incomplete at 7.7 years of age. Evidence suggests that endocranial volume is likely to represent less than 90% adult size at El Sidrón as well as Neandertal male plus Krapina samples, in line with further evidence from endocranial surface histology and dural sinus groove size.
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http://dx.doi.org/10.1126/science.aar3820DOI Listing
March 2018

New Neandertal wrist bones from El Sidrón, Spain (1994-2009).

J Hum Evol 2018 01 31;114:45-75. Epub 2017 Oct 31.

Área de Prehistoria Departamento de Historia, Universidad de Oviedo, Oviedo, Spain.

Twenty-nine carpal bones of Homo neanderthalensis have been recovered from the site of El Sidrón (Asturias, Spain) during excavations between 1994 and 2009, alongside ∼2500 other Neandertal skeletal elements dated to ∼49,000 years ago. All bones of the wrist are represented, including adult scaphoids (n = 6), lunates (n = 2), triquetra (n = 4), pisiforms (n = 2), trapezia (n = 2), trapezoids (n = 5), capitates (n = 5), and hamates (n = 2), as well as one fragmentary and possibly juvenile scaphoid. Several of these carpals appear to belong to the complete right wrist of a single individual. Here we provide qualitative and quantitative morphological descriptions of these carpals, within a comparative context of other European and Near Eastern Neandertals, early and recent Homo sapiens, and other fossil hominins, including Homo antecessor, Homo naledi, and australopiths. Overall, the El Sidrón carpals show characteristics that typically distinguish Neandertals from H. sapiens, such as a relatively flat first metacarpal facet on the trapezium and a more laterally oriented second metacarpal facet on the capitate. However, there are some distinctive features of the El Sidrón carpals compared with most other Neandertals. For example, the tubercle of the trapezium is small with limited projection, while the scaphoid tubercle and hamate hamulus are among the largest seen in other Neandertals. Furthermore, three of the six adult scaphoids show a distinctive os-centrale portion, while another is a bipartite scaphoid with a truncated tubercle. The high frequency of rare carpal morphologies supports other evidence of a close genetic relationship among the Neandertals found at El Sidrón.
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http://dx.doi.org/10.1016/j.jhevol.2017.09.007DOI Listing
January 2018

Diurnal transcriptome atlas of a primate across major neural and peripheral tissues.

Science 2018 03 8;359(6381). Epub 2018 Feb 8.

Regulatory Biology Laboratory, Salk Institute for Biological Studies, 10010, North Torrey Pines Road, La Jolla, CA 92037, USA.

Diurnal gene expression patterns underlie time-of-the-day-specific functional specialization of tissues. However, available circadian gene expression atlases of a few organs are largely from nocturnal vertebrates. We report the diurnal transcriptome of 64 tissues, including 22 brain regions, sampled every 2 hours over 24 hours, from the primate (baboon). Genomic transcription was highly rhythmic, with up to 81.7% of protein-coding genes showing daily rhythms in expression. In addition to tissue-specific gene expression, the rhythmic transcriptome imparts another layer of functional specialization. Most ubiquitously expressed genes that participate in essential cellular functions exhibit rhythmic expression in a tissue-specific manner. The peak phases of rhythmic gene expression clustered around dawn and dusk, with a "quiescent period" during early night. Our findings also unveil a different temporal organization of central and peripheral tissues between diurnal and nocturnal animals.
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http://dx.doi.org/10.1126/science.aao0318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924732PMC
March 2018

The Decreasing Prevalence of the Arcuate Foramen.

World Neurosurg 2018 Feb;110:521-525

Department of Human Anatomy and Physiology, Faculty of Health Sciences, University of Johannesburg, Johannesburg, South Africa.

Background: The arcuate foramen (AF), or ponticulus posticus, is an anatomic variant of the first cervical vertebra that consists of a complete or partial osseous bridge over the groove for the vertebral artery and extends from the posterior aspect of the superior articular facet to the superior lateral border of the posterior arch. The AF has been associated with clinical symptoms, such as headache, migraine, neck pain, shoulder pain, arm pain, and vertebral artery dissection. We aimed to test whether the prevalence of the AF has decreased in the modern human population over the past centuries as a result of reduction in inbreeding and endogamy.

Methods: Possible reduction in the prevalence of the AF was assessed by comparing a 17th century rural sample (n = 108) with a 20th century modern urban sample (n = 192).

Results: When comparing the 17th and the 20th century samples, we found a statistically significant (P = 0.003) reduction of 14.5% (95% confidence interval 4.5-24.5) in the prevalence of the AF.

Conclusions: Prevalence of the AF has been decreasing over the past centuries.
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http://dx.doi.org/10.1016/j.wneu.2017.10.037DOI Listing
February 2018

Sex and age at death estimation from the sternal end of the fourth rib. Does Íşcan's method really work?

Leg Med (Tokyo) 2018 Mar 5;31:24-29. Epub 2017 Dec 5.

Department of Paleobiology, Museo Nacional de Ciencias Naturales, José Gutiérrez Abascal 2, Madrid 28006, Spain; Department of Physical Anthropology, Sociedad de Ciencias Aranzadi, Zorroagagaina, 11, Donostia 20014, Basque Country, Spain.

The fourth rib has been used commonly in order to estimate age at death and even sex in skeletal remains but many often, Iscan's estimates do not adjust to the real age of the individual. Population specific references for sex and age-at-death estimation from the sternal end of the fourth rib are presented for a contemporary Mexican sample. A total of 504 ribs with known sex and age from a morgue sample were studied (444 males, 60 females, 17 to 92 years old). The height and breadth of the sternal end of the rib were sexually dimorphic (p = .000), and allowed a correct sex assignment in 73.3% to 84% of the cases from univariate and multivariate discriminant functions. With regard to age-at-death estimation, the morphological changes summarized by the phases of the sternal end of the fourth rib are correlated with known age in this sample (Spearman's Rho, p = .000). However, the original age intervals tend to underestimate age at death and inaccuracy increases with phase scored in males. Descriptive statistics for rib phase are provided for males and females, and new age-at-death estimates based on transition analysis and Bayesian statistics are provided for the male sample. The test of universally applied methods and the development of population specific references is an important task for forensic anthropology around the world.
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http://dx.doi.org/10.1016/j.legalmed.2017.12.002DOI Listing
March 2018

Making Fat Transfer to Buttocks Safer.

Aesthet Surg J 2017 Oct;37(10):1199-1200

Private practice, Austin, TX. University of Texas Rio Grande Valley School of Medicine, Edinburg, TX. Rutgers New Jersey Medical School, Newark, NJ.

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http://dx.doi.org/10.1093/asj/sjx185DOI Listing
October 2017

The growth pattern of Neandertals, reconstructed from a juvenile skeleton from El Sidrón (Spain).

Science 2017 09;357(6357):1282-1287

Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK.

Ontogenetic studies help us understand the processes of evolutionary change. Previous studies on Neandertals have focused mainly on dental development and inferred an accelerated pace of general growth. We report on a juvenile partial skeleton (El Sidrón J1) preserving cranio-dental and postcranial remains. We used dental histology to estimate the age at death to be 7.7 years. Maturation of most elements fell within the expected range of modern humans at this age. The exceptions were the atlas and mid-thoracic vertebrae, which remained at the 5- to 6-year stage of development. Furthermore, endocranial features suggest that brain growth was not yet completed. The vertebral maturation pattern and extended brain growth most likely reflect Neandertal physiology and ontogenetic energy constraints rather than any fundamental difference in the overall pace of growth in this extinct human.
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http://dx.doi.org/10.1126/science.aan6463DOI Listing
September 2017

The costal remains of the El Sidrón Neanderthal site (Asturias, northern Spain) and their importance for understanding Neanderthal thorax morphology.

J Hum Evol 2017 10 3;111:85-101. Epub 2017 Aug 3.

Paleoanthropology Group, Museo Nacional de Ciencias Naturales (CSIC), J. G. Abascal 2, 28006, Madrid, Spain.

The study of the Neanderthal thorax has attracted the attention of the scientific community for more than a century. It is agreed that Neanderthals have a more capacious thorax than modern humans, but whether this was caused by a medio-lateral or an antero-posterior expansion of the thorax is still debated, and is key to understanding breathing biomechanics and body shape in Neanderthals. The fragile nature of ribs, the metameric structure of the thorax and difficulties in quantifying thorax morphology all contribute to uncertainty regarding precise aspects of Neanderthal thoracic shape. The El Sidrón site has yielded costal remains from the upper to the lower thorax, as well as several proximal rib ends (frequently missing in the Neanderthal record), which help to shed light on Neanderthal thorax shape. We compared the El Sidrón costal elements with ribs from recent modern humans as well as with fossil modern humans and other Neanderthals through traditional morphometric methods and 3D geometric morphometrics, combined with missing data estimation and virtual reconstruction (at the 1st, 5th and 11th costal levels). Our results show that Neanderthals have larger rib heads and articular tubercles than their modern human counterparts. Neanderthal 1st ribs are smaller than in modern humans, whereas 5th and 11th ribs are considerably larger. When we articulated mean ribs (size and shape) with their corresponding vertebral elements, we observed that compared to modern humans the Neanderthal thorax is medio-laterally expanded at every level, especially at T5 and T11. Therefore, in the light of evidence from the El Sidrón costal remains, we hypothesize that the volumetric expansion of the Neanderthal thorax proposed by previous authors would mainly be produced by a medio-lateral expansion of the thorax.
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http://dx.doi.org/10.1016/j.jhevol.2017.06.003DOI Listing
October 2017