Luis F Parada

Luis F Parada

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Luis F Parada

Luis F Parada

Publications by authors named "Luis F Parada"

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Cell-of-origin susceptibility to glioblastoma formation declines with neural lineage restriction.

Nat Neurosci 2019 04 18;22(4):545-555. Epub 2019 Feb 18.

Brain Tumor Center, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1038/s41593-018-0333-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6594191PMC
April 2019

Cell of Origin and Cancer Stem Cells in Tumor Suppressor Mouse Models of Glioblastoma.

Cold Spring Harb Symp Quant Biol 2016 4;81:31-36. Epub 2016 Nov 4.

Brain Tumor Center and Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065.

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http://dx.doi.org/10.1101/sqb.2016.81.030973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353557PMC
February 2018

TrkB dependent adult hippocampal progenitor differentiation mediates sustained ketamine antidepressant response.

Nat Commun 2017 11 21;8(1):1668. Epub 2017 Nov 21.

Department of Developmental Biology & Kent Waldrep Center for Basic Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.

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http://dx.doi.org/10.1038/s41467-017-01709-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698402PMC
November 2017

Brain Tumor Stem Cells Remain in Play.

J Clin Oncol 2017 07 22;35(21):2428-2431. Epub 2017 Jun 22.

Luis F. Parada, Memorial Sloan Kettering Cancer Center, New York, NY; Peter B. Dirks, University of Toronto, Toronto, Ontario, Canada; and Robert J. Wechsler-Reya, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA.

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http://dx.doi.org/10.1200/JCO.2017.73.9540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516484PMC
July 2017

Cell of origin of glioma: biological and clinical implications.

Br J Cancer 2016 Dec 10;115(12):1445-1450. Epub 2016 Nov 10.

Brain Tumor Center and Cancer Biology & Genetics Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

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http://dx.doi.org/10.1038/bjc.2016.354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5155355PMC
December 2016

Adult Lineage-Restricted CNS Progenitors Specify Distinct Glioblastoma Subtypes.

Cancer Cell 2015 Oct;28(4):429-440

Department of Developmental Biology, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2015.09.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607935PMC
October 2015

Cell of origin for malignant gliomas and its implication in therapeutic development.

Cold Spring Harb Perspect Biol 2015 Jan 29;7(5). Epub 2015 Jan 29.

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105.

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http://dx.doi.org/10.1101/cshperspect.a020610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448618PMC
January 2015

NF1 regulation of RAS/ERK signaling is required for appropriate granule neuron progenitor expansion and migration in cerebellar development.

Genes Dev 2014 Nov;28(21):2407-20

Department of Developmental Biology, Kent Waldrep Foundation Center for Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical School, Dallas, Texas 75390, USA

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http://dx.doi.org/10.1101/gad.246603.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215185PMC
November 2014

The soft underbelly of tumor cells.

Cell Res 2014 Aug 30;24(8):910-1. Epub 2014 May 30.

Department of Developmental Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1038/cr.2014.72DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123293PMC
August 2014

PTEN knockdown alters dendritic spine/protrusion morphology, not density.

J Comp Neurol 2014 Apr;522(5):1171-90

Department of Neurology & Neurotherapeutics, The University of Texas Southwestern Medical Center, Dallas, Texas, 75390-8813; Neuroscience Graduate Program, The University of Texas Southwestern Medical Center, Dallas, Texas, 75390-8813.

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http://dx.doi.org/10.1002/cne.23488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945606PMC
April 2014

Analysis of FMR1 deletion in a subpopulation of post-mitotic neurons in mouse cortex and hippocampus.

Autism Res 2014 Feb 9;7(1):60-71. Epub 2014 Jan 9.

Department of Developmental Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1002/aur.1342DOI Listing
February 2014

Preclinical therapeutic efficacy of a novel pharmacologic inducer of apoptosis in malignant peripheral nerve sheath tumors.

Cancer Res 2014 Jan 27;74(2):586-97. Epub 2013 Nov 27.

Authors' Affiliations: Departments of Dermatology, Developmental Biology, and Biochemistry, and Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1934DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947005PMC
January 2014

Trk B signaling in dopamine 1 receptor neurons regulates food intake and body weight.

Obesity (Silver Spring) 2013 Nov 31;21(11):2372-6. Epub 2013 May 31.

Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://doi.wiley.com/10.1002/oby.20382
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http://dx.doi.org/10.1002/oby.20382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742719PMC
November 2013

The Ras GTPase-activating protein neurofibromin 1 promotes the positive selection of thymocytes.

Mol Immunol 2013 Oct 20;55(3-4):292-302. Epub 2013 Mar 20.

Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1016/j.molimm.2013.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646930PMC
October 2013

Injury signals cooperate with Nf1 loss to relieve the tumor-suppressive environment of adult peripheral nerve.

Cell Rep 2013 Oct 26;5(1):126-36. Epub 2013 Sep 26.

MRC Laboratory for Molecular Cell Biology, University College London, Gower Street, London WC1E 6BT, UK; UCL Cancer Institute, University College London, Gower Street, London WC1E 6BT, UK.

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http://dx.doi.org/10.1016/j.celrep.2013.08.033DOI Listing
October 2013

Transcription factor Sox11 is essential for both embryonic and adult neurogenesis.

Dev Dyn 2013 Jun 28;242(6):638-53. Epub 2013 Apr 28.

School of Life Sciences, Arizona State University, Tempe, Arizona, USA.

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http://doi.wiley.com/10.1002/dvdy.23962
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http://dx.doi.org/10.1002/dvdy.23962DOI Listing
June 2013

The tumor suppressor CDKN3 controls mitosis.

J Cell Biol 2013 Jun 17;201(7):997-1012. Epub 2013 Jun 17.

Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, IN 46202, USA.

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http://jcb.rupress.org/content/201/7/997.full.pdf
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http://www.jcb.org/cgi/doi/10.1083/jcb.201205125
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http://dx.doi.org/10.1083/jcb.201205125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691455PMC
June 2013

Dysregulation of synaptic plasticity precedes appearance of morphological defects in a Pten conditional knockout mouse model of autism.

Proc Natl Acad Sci U S A 2013 Mar 4;110(12):4738-43. Epub 2013 Mar 4.

Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, New York, NY 10461, USA.

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http://dx.doi.org/10.1073/pnas.1222803110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607034PMC
March 2013

PTEN signaling in autism spectrum disorders.

Curr Opin Neurobiol 2012 Oct 2;22(5):873-9. Epub 2012 Jun 2.

Department of Developmental Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9133, USA.

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http://dx.doi.org/10.1016/j.conb.2012.05.004DOI Listing
October 2012

Neurofibromatosis type 1: modeling CNS dysfunction.

J Neurosci 2012 Oct;32(41):14087-93

Washington University School of Medicine, St. Louis, Missouri 63110, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.3242-12.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3477849PMC
October 2012

Conditional ablation of brain-derived neurotrophic factor-TrkB signaling impairs striatal neuron development.

Proc Natl Acad Sci U S A 2012 Sep 4;109(38):15491-6. Epub 2012 Sep 4.

Department of Developmental Biology and Kent Waldrep Center for Basic Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1073/pnas.1212899109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458400PMC
September 2012

A restricted cell population propagates glioblastoma growth after chemotherapy.

Nature 2012 Aug;488(7412):522-6

Department of Developmental Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9133, USA.

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http://dx.doi.org/10.1038/nature11287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427400PMC
August 2012

Overactivation of Ras signaling pathway in CD133+ MPNST cells.

J Neurooncol 2012 Jul 8;108(3):423-34. Epub 2012 Apr 8.

KUMC-Molecular Medicine Laboratory, Department of Medicine, The University of Kansas Medical Center, Kansas city, KS 66160, USA.

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http://dx.doi.org/10.1007/s11060-012-0852-1DOI Listing
July 2012

Phenotypic characterization of transgenic mice harboring Nf1+/- or Nf1-/- osteoclasts in otherwise Nf1+/+ background.

J Cell Biochem 2012 Jun;113(6):2136-46

Department of Cell Biology and Anatomy, University of Turku, and Department of Dermatology, Turku University Hospital, Turku, Finland.

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http://dx.doi.org/10.1002/jcb.24088DOI Listing
June 2012

Neurofibromin modulates adult hippocampal neurogenesis and behavioral effects of antidepressants.

J Neurosci 2012 Mar;32(10):3529-39

Department of Developmental Biology and Kent Waldrep Center for Basic Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9133, USA.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.3469-11.2
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http://dx.doi.org/10.1523/JNEUROSCI.3469-11.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511887PMC
March 2012

TrkA gene ablation in basal forebrain results in dysfunction of the cholinergic circuitry.

J Neurosci 2012 Mar;32(12):4065-79

Department of Developmental Biology, University of Texas Southwestern Medical School, Dallas, TX 75390-9133, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.6314-11.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3403817PMC
March 2012

Malignant glioma: lessons from genomics, mouse models, and stem cells.

Cell 2012 Mar;149(1):36-47

Department of Developmental Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1016/j.cell.2012.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719882PMC
March 2012

Genetic modeling of gliomas in mice: new tools to tackle old problems.

Glia 2011 Aug 8;59(8):1155-68. Epub 2011 Feb 8.

Department of Stem Cell Biology and Regenerative Medicine, Cleveland Clinic, Ohio, USA.

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http://doi.wiley.com/10.1002/glia.21142
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http://dx.doi.org/10.1002/glia.21142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619979PMC
August 2011

Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle.

Genes Dev 2011 Aug;25(15):1595-600

Department of Developmental Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1101/gad.16750211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182017PMC
August 2011

Susceptible stages in Schwann cells for NF1-associated plexiform neurofibroma development.

Cancer Res 2011 Jul 6;71(13):4686-95. Epub 2011 May 6.

Departments of Developmental Biology and Dermatology, Simmons Comprehensive Cancer Center, The University of Texas Southwestern Medical Center, Dallas, Texas 75390-9133, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-4577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145496PMC
July 2011

Stem cells in brain tumor development.

Curr Top Dev Biol 2011 ;94:15-44

University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA.

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http://dx.doi.org/10.1016/B978-0-12-380916-2.00002-4DOI Listing
April 2011

Glioblastoma multiforme: a perspective on recent findings in human cancer and mouse models.

BMB Rep 2011 Mar;44(3):158-64

Department of Developmental Biology, The University of Texas Southwestern Medical Center at Dallas, 75390, USA.

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http://dx.doi.org/10.5483/BMBRep.2011.44.3.158DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3719878PMC
March 2011

Glia- and neuron-specific functions of TrkB signalling during retinal degeneration and regeneration.

Nat Commun 2011 Feb 8;2:189. Epub 2011 Feb 8.

Department of Molecular Neurobiology, Tokyo Metropolitan Institute for Neuroscience, 2-6 Musashidai, Fuchu, Tokyo 183-8526, Japan.

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http://dx.doi.org/10.1038/ncomms1190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105320PMC
February 2011

Dock3 induces axonal outgrowth by stimulating membrane recruitment of the WAVE complex.

Proc Natl Acad Sci U S A 2010 Apr 5;107(16):7586-91. Epub 2010 Apr 5.

Department of Molecular Neurobiology, Tokyo Metropolitan Institute for Neuroscience, Fuchu, Tokyo 183-8526, Japan.

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http://dx.doi.org/10.1073/pnas.0914514107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867726PMC
April 2010

Signaling in malignant astrocytomas: role of neural stem cells and its therapeutic implications.

Clin Cancer Res 2009 Dec 24;15(23):7124-9. Epub 2009 Nov 24.

The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390-9933, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-0433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2787668PMC
December 2009

Regulation of hippocampal progenitor cell survival, proliferation and dendritic development by BDNF.

Mol Neurodegener 2009 Dec 21;4:52. Epub 2009 Dec 21.

Committee on Neurobiology, University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1186/1750-1326-4-52DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2806355PMC
December 2009

Loss of Tsc1, but not Pten, in renal tubular cells causes polycystic kidney disease by activating mTORC1.

Hum Mol Genet 2009 Nov 19;18(22):4428-41. Epub 2009 Aug 19.

Department of Developmental Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9133, USA.

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http://dx.doi.org/10.1093/hmg/ddp398DOI Listing
November 2009

PTEN dosage is essential for neurofibroma development and malignant transformation.

Proc Natl Acad Sci U S A 2009 Nov 21;106(46):19479-84. Epub 2009 Oct 21.

Department of Molecular and Medical Pharmacology, Institute for Molecular Medicine, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1073/pnas.0910398106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2765459PMC
November 2009

Mice lacking neurofibromin develop gastric hyperplasia.

Am J Physiol Gastrointest Liver Physiol 2009 Oct 6;297(4):G751-61. Epub 2009 Aug 6.

Department of Developmental Biology and Kent Waldrep Foundation Center for Basic Neuroscience Research on NerveGrowth and Regeneration, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9133, USA.

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http://dx.doi.org/10.1152/ajpgi.00007.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763809PMC
October 2009

A motor driving PTEN.

Nat Cell Biol 2009 Oct;11(10):1177-9

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http://dx.doi.org/10.1038/ncb1009-1177DOI Listing
October 2009

Ral overactivation in malignant peripheral nerve sheath tumors.

Mol Cell Biol 2009 Jul 4;29(14):3964-74. Epub 2009 May 4.

Department of Medicine, KUMC-Molecular Medicine Laboratory, University of Kansas School of Medicine, 1000 Hixon, Mail Stop 4037, 3901 Rainbow Blvd., Kansas City, KS 66160, USA.

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http://dx.doi.org/10.1128/MCB.01153-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2704746PMC
July 2009

Cell of origin and microenvironment contribution for NF1-associated dermal neurofibromas.

Cell Stem Cell 2009 May;4(5):453-63

Department of Developmental Biology, The University of Texas Southwestern Medical Center, Dallas, TX 75390-9133, USA.

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http://dx.doi.org/10.1016/j.stem.2009.03.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737469PMC
May 2009

Inducible site-specific recombination in neural stem/progenitor cells.

Genesis 2009 Feb;47(2):122-31

Department of Developmental Biology and Kent Waldrep Foundation Center for Basic Neuroscience Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9133, USA.

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http://dx.doi.org/10.1002/dvg.20465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2708938PMC
February 2009

Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice.

J Neurosci 2009 Feb;29(6):1773-83

Department of Developmental Biology and Kent Waldrep Foundation Center for Basic Neuroscience Research on Nerve Growth and Regeneration, and University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.5685-08.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904448PMC
February 2009

Ras signaling influences permissiveness of malignant peripheral nerve sheath tumor cells to oncolytic herpes.

Am J Pathol 2008 Dec 6;173(6):1861-72. Epub 2008 Nov 6.

Department of Medicine, Division of Hematology, Oncology, and Transplantation, Kansas University Medical Center, Kansas City, KS 66160, USA.

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http://dx.doi.org/10.2353/ajpath.2008.080376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2626396PMC
December 2008

NF1 loss disrupts Schwann cell-axonal interactions: a novel role for semaphorin 4F.

Genes Dev 2008 Dec;22(23):3335-48

MRC Laboratory for Molecular Cell Biology, Department of Cell and Developmental Biology and the UCL Cancer Institute, University College London, London WC1E 6BT, United Kingdom.

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http://dx.doi.org/10.1101/gad.490608DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2600763PMC
December 2008

Neurofibromin regulation of ERK signaling modulates GABA release and learning.

Cell 2008 Oct;135(3):549-60

Department of Neurobiology, Brain Research Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.cell.2008.09.060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673196PMC
October 2008

TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment.

Neuron 2008 Aug;59(3):399-412

Department of Developmental Biology, Kent Waldrep Center for Basic Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, TX 75390-9133, USA.

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http://dx.doi.org/10.1016/j.neuron.2008.06.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2655199PMC
August 2008

Neurotrophin-dependent dendritic filopodial motility: a convergence on PI3K signaling.

J Neurosci 2008 Jul;28(27):7006-12

Department of Developmental Biology and Kent Waldrep Foundation Center for Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical School, Dallas, Texas 75390-9133, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.0195-08.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397478PMC
July 2008

Pten haploinsufficiency accelerates formation of high-grade astrocytomas.

Cancer Res 2008 May;68(9):3286-94

Department of Developmental Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9133, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-6867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760841PMC
May 2008

The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells.

Cancer Cell 2008 Feb;13(2):129-40

Center for Stem Cell Biology, Howard Hughes Medical Institute, Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109-2216, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S153561080800006
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http://dx.doi.org/10.1016/j.ccr.2008.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566828PMC
February 2008

Neurofibromin is required for barrel formation in the mouse somatosensory cortex.

J Neurosci 2008 Feb;28(7):1580-7

Department of Developmental Biology and Kent Waldrep Center for Basic Neuroscience Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9133, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.5236-07.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760344PMC
February 2008

A seizure-prone phenotype is associated with altered free-running rhythm in Pten mutant mice.

Brain Res 2007 Sep 20;1168:112-23. Epub 2007 Jul 20.

Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1016/j.brainres.2007.06.074DOI Listing
September 2007

A crucial role for Olig2 in white matter astrocyte development.

Development 2007 May 11;134(10):1887-99. Epub 2007 Apr 11.

Department of Developmental Biology and Kent Waldrep Foundation Center for Basic Neuroscience Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1242/dev.02847DOI Listing
May 2007

Multiple roles for neurofibromin in skeletal development and growth.

Hum Mol Genet 2007 Apr 22;16(8):874-86. Epub 2007 Feb 22.

FG Development and Disease, Max Planck Institute for Molecular Genetics, Berlin, Germany.

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http://dx.doi.org/10.1093/hmg/ddm032DOI Listing
April 2007

Deletion of Nf1 in neurons induces increased axon collateral branching after dorsal root injury.

J Neurosci 2007 Feb;27(8):2124-34

Department of Developmental Biology and Kent Waldrep Foundation Center for Basic Neuroscience Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9133, USA.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.4363-06.2
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http://dx.doi.org/10.1523/JNEUROSCI.4363-06.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673560PMC
February 2007

Molecular regulation of visual system development: more than meets the eye.

Genes Dev 2007 Feb;21(4):367-78

Department of Developmental Biology, Kent Waldrep Foundation Center for Basic Neuroscience Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, Texas 75235, USA.

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http://dx.doi.org/10.1101/gad.1504307DOI Listing
February 2007

Brain-derived neurotrophic factor conditional knockouts show gender differences in depression-related behaviors.

Biol Psychiatry 2007 Jan 12;61(2):187-97. Epub 2006 May 12.

Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX 75390-9070, USA.

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http://dx.doi.org/10.1016/j.biopsych.2006.03.021DOI Listing
January 2007

Receptor tyrosine kinase B-mediated excitatory synaptogenesis.

Prog Brain Res 2006 ;157:15-24

Center for Developmental Biology, and Kent Waldrep Foundation Center for Basic Neuroscience Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1016/s0079-6123(06)57002-5DOI Listing
January 2007

Brn3a and Klf7 cooperate to control TrkA expression in sensory neurons.

Dev Biol 2006 Dec 30;300(2):758-69. Epub 2006 Aug 30.

Center for Developmental Biology and Kent Waldrep Center for Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, TX 75390-9133, USA.

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http://dx.doi.org/10.1016/j.ydbio.2006.08.062DOI Listing
December 2006

ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae.

Cell Metab 2006 Dec;4(6):441-51

Department of Molecular and Human Genetics, Bone Disease program of Texas, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1016/j.cmet.2006.10.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756713PMC
December 2006

Diminished hypothalamic bdnf expression and impaired VMH function are associated with reduced SF-1 gene dosage.

J Comp Neurol 2006 Oct;498(5):637-48

Department of Physiology, University of California, San Francisco, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1002/cne.21070DOI Listing
October 2006

Development of a steroidogenic factor 1/Cre transgenic mouse line.

Genesis 2006 Sep;44(9):419-24

Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390-8857, USA.

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http://doi.wiley.com/10.1002/dvg.20231
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September 2006

Nf1+/- mast cells induce neurofibroma like phenotypes through secreted TGF-beta signaling.

Hum Mol Genet 2006 Aug 11;15(16):2421-37. Epub 2006 Jul 11.

Department of Pediatrics, and Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, 1044 W. Walnut Street, Indianapolis, IN 46202, USA.

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http://academic.oup.com/hmg/article/15/16/2421/644093/Nf1-ma
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http://dx.doi.org/10.1093/hmg/ddl165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024714PMC
August 2006

Retinoic acid delineates the topography of neuronal plasticity in postnatal cerebral cortex.

Eur J Neurosci 2006 Jul 12;24(2):329-40. Epub 2006 Jul 12.

Eunice Kennedy Shriver Center for Mental Retardation, 200 Trapelo Road., Waltham, MA 02452, USA.

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http://dx.doi.org/10.1111/j.1460-9568.2006.04934.xDOI Listing
July 2006

Pten regulates neuronal arborization and social interaction in mice.

Neuron 2006 May;50(3):377-88

Kent Waldrep Foundation Center for Basic Neuroscience Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1016/j.neuron.2006.03.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902853PMC
May 2006

Neuron-specific enolase-cre mouse line with cre activity in specific neuronal populations.

Genesis 2006 Mar;44(3):130-5

Center for Developmental Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9133, USA.

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http://dx.doi.org/10.1002/gene.20197DOI Listing
March 2006

Effect of p75NTR on the regulation of naturally occurring cell death and retinal ganglion cell number in the mouse eye.

Dev Biol 2006 Feb 15;290(1):57-65. Epub 2005 Dec 15.

Department of Molecular Neurobiology, Tokyo Metropolitan Institute for Neuroscience, Fuchu, Tokyo 183-8526, Japan.

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http://dx.doi.org/10.1016/j.ydbio.2005.08.051DOI Listing
February 2006

Differential expression of the four untranslated BDNF exons in the adult mouse brain.

J Neurosci Res 2006 Feb;83(2):211-21

Center for Developmental Biology and Kent Waldrep Foundation Center for Basic Neuroscience Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9133, USA.

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http://dx.doi.org/10.1002/jnr.20728DOI Listing
February 2006

Expression of the insulin receptor-related receptor is induced by the preovulatory surge of luteinizing hormone in thecal-interstitial cells of the rat ovary.

Endocrinology 2006 Jan 29;147(1):155-65. Epub 2005 Sep 29.

Division of Neuroscience, Oregon Regional Primate Research Center, 505 N.W. 185th Avenue, Beaverton, Oregon 97006-3448, USA.

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http://dx.doi.org/10.1210/en.2005-0386DOI Listing
January 2006

A critical role for dorsal progenitors in cortical myelination.

J Neurosci 2006 Jan;26(4):1275-80

Center for Developmental Biology, Kent Waldrep Foundation Center for Basic Neuroscience Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.4717-05.2006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6674567PMC
January 2006

Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation.

Development 2005 Dec;132(24):5577-88

Center for Developmental Biology and Kent Waldrep Foundation Center for Basic Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, TX 75390-9133, USA.

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http://dev.biologists.org/cgi/doi/10.1242/dev.02162
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760350PMC
December 2005

Hormonal regulation of male reproductive tract development.

Ann N Y Acad Sci 2005 Dec;1061:1-8

Center for Developmental Biology, University of Texas, Southwestern Medical Center, 6000 Harry Hines Blvd., Dallas, TX 75390-9133, USA.

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http://dx.doi.org/10.1196/annals.1336.002DOI Listing
December 2005

TrkB signaling regulates the developmental maturation of the somatosensory cortex.

Int J Dev Neurosci 2005 Oct;23(6):523-36

Center for Developmental Biology and Kent Waldrep Foundation Center for Basic Neuroscience, Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, TX 75390-9133, USA.

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http://dx.doi.org/10.1016/j.ijdevneu.2005.04.003DOI Listing
October 2005

Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma.

Cancer Cell 2005 Aug;8(2):119-30

Center for Developmental Biology and Kent Waldrep Foundation Center for Basic Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1016/j.ccr.2005.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024718PMC
August 2005

Transcription factor KLF7 is important for neuronal morphogenesis in selected regions of the nervous system.

Mol Cell Biol 2005 Jul;25(13):5699-711

Laboratory of Genetics and Organogenesis, Research Division of the Hospital for Special Surgery, and Department of Physiology and Biophysics at Weill Medical College of Cornell University, 535 East 70th St., New York, New York 10021, USA.

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http://dx.doi.org/10.1128/MCB.25.13.5699-5711.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1157008PMC
July 2005

Ephrin-B3 is a myelin-based inhibitor of neurite outgrowth.

Proc Natl Acad Sci U S A 2005 Jul 14;102(30):10694-9. Epub 2005 Jul 14.

Center for Developmental Biology, University of Texas Southwestern Medical Center, 6000 Harry Hines Boulevard, Dallas, TX 75390-9133, USA.

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http://dx.doi.org/10.1073/pnas.0504021102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1175581PMC
July 2005

The zinc finger transcription factor Klf7 is required for TrkA gene expression and development of nociceptive sensory neurons.

Genes Dev 2005 Jun;19(11):1354-64

Center for Developmental Biology and Kent Waldrep Center for Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, 75390-9133, USA.

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http://dx.doi.org/10.1101/gad.1227705DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1142558PMC
June 2005

Temporally regulated expression of Cre recombinase in neural stem cells.

Genesis 2005 Apr;41(4):147-53

Department of Pediatrics, U.T. Southwestern Medical Center, Dallas, Texas 75390-9063, USA.

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http://dx.doi.org/10.1002/gene.20110DOI Listing
April 2005

TrkB has a cell-autonomous role in the establishment of hippocampal Schaffer collateral synapses.

J Neurosci 2005 Apr;25(15):3774-86

Center for Developmental Biology and Kent Waldrep Foundation Center for Basic Neuroscience Research on Nerve Growth and Regeneration, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9133, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.0041-05.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724922PMC
April 2005

Role of neurotrophin-4/5 in neural cell death during retinal development and ischemic retinal injury in vivo.

Invest Ophthalmol Vis Sci 2005 Feb;46(2):669-73

Department of Molecular Neurobiology, Tokyo Metropolitan Institute for Neuroscience, Fuchu, Tokyo 183-8526, Japan.

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http://dx.doi.org/10.1167/iovs.04-0826DOI Listing
February 2005