Publications by authors named "Luis Enjuanes"

100Publications

Middle East Respiratory Syndrome Coronavirus Gene 5 Modulates Pathogenesis in Mice.

Authors:
Javier Gutierrez-Alvarez Li Wang Raul Fernandez-Delgado Kun Li Paul B McCray Stanley Perlman Isabel Sola Sonia Zuñiga Luis Enjuanes

J Virol 2021 01 13;95(3). Epub 2021 Jan 13.

Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain

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January 2021

Cross-neutralization activity against SARS-CoV-2 is present in currently available intravenous immunoglobulins.

Authors:
José María Díez Carolina Romero Júlia Vergara-Alert Melissa Belló-Perez Jordi Rodon José Manuel Honrubia Joaquim Segalés Isabel Sola Luis Enjuanes Rodrigo Gajardo

Immunotherapy 2020 12 8;12(17):1247-1255. Epub 2020 Sep 8.

Bioscience Research & Development, Grifols, Barcelona, Spain.

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December 2020

Statement in support of the scientists, public health professionals, and medical professionals of China combatting COVID-19.

Authors:
Charles Calisher Dennis Carroll Rita Colwell Ronald B Corley Peter Daszak Christian Drosten Luis Enjuanes Jeremy Farrar Hume Field Josie Golding Alexander Gorbalenya Bart Haagmans James M Hughes William B Karesh Gerald T Keusch Sai Kit Lam Juan Lubroth John S Mackenzie Larry Madoff Jonna Mazet Peter Palese Stanley Perlman Leo Poon Bernard Roizman Linda Saif Kanta Subbarao Mike Turner

Lancet 2020 03 19;395(10226):e42-e43. Epub 2020 Feb 19.

The Wellcome Trust, London, UK.

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March 2020

Minimum Determinants of Transmissible Gastroenteritis Virus Enteric Tropism Are Located in the N-Terminus of Spike Protein.

Authors:
Carlos M Sanchez Alejandro Pascual-Iglesias Isabel Sola Sonia Zuñiga Luis Enjuanes

Pathogens 2019 Dec 18;9(1). Epub 2019 Dec 18.

Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin 3, 28049 Madrid, Spain.

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December 2019

Recombinant Chimeric Transmissible Gastroenteritis Virus (TGEV) - Porcine Epidemic Diarrhea Virus (PEDV) Virus Provides Protection against Virulent PEDV.

Authors:
Alejandro Pascual-Iglesias Carlos M Sanchez Zoltan Penzes Isabel Sola Luis Enjuanes Sonia Zuñiga

Viruses 2019 07 25;11(8). Epub 2019 Jul 25.

Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin 3, 28049 Madrid, Spain.

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July 2019

Severe acute respiratory syndrome coronavirus ORF3a protein activates the NLRP3 inflammasome by promoting TRAF3-dependent ubiquitination of ASC.

Authors:
Kam-Leung Siu Kit-San Yuen Carlos Castaño-Rodriguez Zi-Wei Ye Man-Lung Yeung Sin-Yee Fung Shuofeng Yuan Chi-Ping Chan Kwok-Yung Yuen Luis Enjuanes Dong-Yan Jin

FASEB J 2019 08 29;33(8):8865-8877. Epub 2019 Apr 29.

School of Biomedical Sciences, The University of Hong Kong, PokFuLam, Hong Kong.

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August 2019

Towards a solution to MERS: protective human monoclonal antibodies targeting different domains and functions of the MERS-coronavirus spike glycoprotein.

Authors:
Ivy Widjaja Chunyan Wang Rien van Haperen Javier Gutiérrez-Álvarez Brenda van Dieren Nisreen M A Okba V Stalin Raj Wentao Li Raul Fernandez-Delgado Frank Grosveld Frank J M van Kuppeveld Bart L Haagmans Luis Enjuanes Dubravka Drabek Berend-Jan Bosch

Emerg Microbes Infect 2019 ;8(1):516-530

a Virology Division, Department of Infectious Diseases & Immunology, Faculty of Veterinary Medicine , Utrecht University , Utrecht , Netherlands.

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June 2019

S1 Subunit of Spike Protein from a Current Highly Virulent Porcine Epidemic Diarrhea Virus Is an Important Determinant of Virulence in Piglets.

Authors:
Tohru Suzuki Yutaka Terada Luis Enjuanes Seiichi Ohashi Wataru Kamitani

Viruses 2018 08 30;10(9). Epub 2018 Aug 30.

Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 5650871, Japan.

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August 2018

Adaptive Evolution of MERS-CoV to Species Variation in DPP4.

Authors:
Michael Letko Kerri Miazgowicz Rebekah McMinn Stephanie N Seifert Isabel Sola Luis Enjuanes Aaron Carmody Neeltje van Doremalen Vincent Munster

Cell Rep 2018 08;24(7):1730-1737

Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA. Electronic address:

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August 2018

Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection.

Authors:
V Stalin Raj Nisreen M A Okba Javier Gutierrez-Alvarez Dubravka Drabek Brenda van Dieren W Widagdo Mart M Lamers Ivy Widjaja Raul Fernandez-Delgado Isabel Sola Albert Bensaid Marion P Koopmans Joaquim Segalés Albert D M E Osterhaus Berend Jan Bosch Luis Enjuanes Bart L Haagmans

Sci Adv 2018 08 8;4(8):eaas9667. Epub 2018 Aug 8.

Department of Viroscience, Erasmus Medical Center, Rotterdam, Netherlands.

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August 2018

Role of Severe Acute Respiratory Syndrome Coronavirus Viroporins E, 3a, and 8a in Replication and Pathogenesis.

Authors:
Carlos Castaño-Rodriguez Jose M Honrubia Javier Gutiérrez-Álvarez Marta L DeDiego Jose L Nieto-Torres Jose M Jimenez-Guardeño Jose A Regla-Nava Raul Fernandez-Delgado Carmina Verdia-Báguena Maria Queralt-Martín Grazyna Kochan Stanley Perlman Vicente M Aguilella Isabel Sola Luis Enjuanes

mBio 2018 05 22;9(3). Epub 2018 May 22.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain

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May 2018

MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection.

Authors:
Javier Canton Anthony R Fehr Raúl Fernandez-Delgado Francisco J Gutierrez-Alvarez Maria T Sanchez-Aparicio Adolfo García-Sastre Stanley Perlman Luis Enjuanes Isabel Sola

PLoS Pathog 2018 01 25;14(1):e1006838. Epub 2018 Jan 25.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Madrid, Spain.

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January 2018

Erratum to: Role of transcription regulatory sequence in regulation of gene expression and replication of porcine reproductive and respiratory syndrome virus.

Authors:
Chengbao Wang Han Meng Yujin Gao Hui Gao Kangkang Guo Fernando Almazan Isabel Sola Luis Enjuanes Yanming Zhang Levon Abrahamyan

Vet Res 2017 09 20;48(1):54. Epub 2017 Sep 20.

Swine and Poultry Infectious Diseases Research Center (CRIPA) and Research Group on Infectious Diseases in Production Animals (GREMIP), Faculty of Veterinary Medicine, Université de Montréal, 3200 Sicotte, Saint-Hyacinthe, QC, J2S 2M2, Canada.

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September 2017

Role of transcription regulatory sequence in regulation of gene expression and replication of porcine reproductive and respiratory syndrome virus.

Authors:
Chengbao Wang Han Meng Yujin Gao Hui Gao Kangkang Guo Fernando Almazan Isabel Sola Luis Enjuanes Yanming Zhang Levon Abrahamyan

Vet Res 2017 08 10;48(1):41. Epub 2017 Aug 10.

Swine and Poultry Infectious Diseases Research Center (CRIPA) and Research Group on Infectious Diseases in Production Animals (GREMIP), Faculty of Veterinary Medicine, Université de Montréal, 3200 Sicotte, Saint-Hyacinthe, QC, J2S 2M2, Canada.

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August 2017

Generation of a DNA-Launched Reporter Replicon Based on Dengue Virus Type 2 as a Multipurpose Platform.

Authors:
Jose A Usme-Ciro Jaime A Lopera Diego A Alvarez Luis Enjuanes Fernando Almazán

Intervirology 2016 23;59(5-6):275-282. Epub 2017 Jun 23.

Molecular and Translational Medicine Group, Facultad de Medicina, Universidad de Antioquia, Medellin, Colombia.

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June 2017

Allosteric inhibition of aminopeptidase N functions related to tumor growth and virus infection.

Authors:
César Santiago Gaurav Mudgal Juan Reguera Rosario Recacha Sébastien Albrecht Luis Enjuanes José M Casasnovas

Sci Rep 2017 04 10;7:46045. Epub 2017 Apr 10.

Centro Nacional de Biotecnología (CNB-CSIC), Darwin 3, Campus Universidad Autónoma de Madrid, 28049 Madrid, Spain.

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April 2017

SARS-CoV-Encoded Small RNAs Contribute to Infection-Associated Lung Pathology.

Authors:
Lucía Morales Juan Carlos Oliveros Raúl Fernandez-Delgado Benjamin Robert tenOever Luis Enjuanes Isabel Sola

Cell Host Microbe 2017 Mar 16;21(3):344-355. Epub 2017 Feb 16.

Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Madrid, 28049, Spain.

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March 2017

Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses.

Authors:
Huib H Rabouw Martijn A Langereis Robert C M Knaap Tim J Dalebout Javier Canton Isabel Sola Luis Enjuanes Peter J Bredenbeek Marjolein Kikkert Raoul J de Groot Frank J M van Kuppeveld

PLoS Pathog 2016 Oct 26;12(10):e1005982. Epub 2016 Oct 26.

Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

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October 2016

Virulence factors in porcine coronaviruses and vaccine design.

Authors:
Sonia Zuñiga Alejandro Pascual-Iglesias Carlos M Sanchez Isabel Sola Luis Enjuanes

Virus Res 2016 12 7;226:142-151. Epub 2016 Jul 7.

Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin 3, Madrid, Spain. Electronic address:

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December 2016

Mutagenesis of Coronavirus nsp14 Reveals Its Potential Role in Modulation of the Innate Immune Response.

Authors:
Martina Becares Alejandro Pascual-Iglesias Aitor Nogales Isabel Sola Luis Enjuanes Sonia Zuñiga

J Virol 2016 06 12;90(11):5399-5414. Epub 2016 May 12.

Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain.

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June 2016

Continuous and Discontinuous RNA Synthesis in Coronaviruses.

Authors:
Isabel Sola Fernando Almazán Sonia Zúñiga Luis Enjuanes

Annu Rev Virol 2015 Nov;2(1):265-88

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología-Consejo Superior de Investigaciones Científicas (CNB-CSIC), 28049 Madrid, Spain; email:

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November 2015

Identification of the Mechanisms Causing Reversion to Virulence in an Attenuated SARS-CoV for the Design of a Genetically Stable Vaccine.

Authors:
Jose M Jimenez-Guardeño Jose A Regla-Nava Jose L Nieto-Torres Marta L DeDiego Carlos Castaño-Rodriguez Raul Fernandez-Delgado Stanley Perlman Luis Enjuanes

PLoS Pathog 2015 Oct 29;11(10):e1005215. Epub 2015 Oct 29.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain.

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October 2015

Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome.

Authors:
Jose L Nieto-Torres Carmina Verdiá-Báguena Jose M Jimenez-Guardeño Jose A Regla-Nava Carlos Castaño-Rodriguez Raul Fernandez-Delgado Jaume Torres Vicente M Aguilella Luis Enjuanes

Virology 2015 Nov 29;485:330-9. Epub 2015 Aug 29.

Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, 28049 Madrid, Spain. Electronic address:

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November 2015

Relevance of Viroporin Ion Channel Activity on Viral Replication and Pathogenesis.

Authors:
Jose L Nieto-Torres Carmina Verdiá-Báguena Carlos Castaño-Rodriguez Vicente M Aguilella Luis Enjuanes

Viruses 2015 Jul 3;7(7):3552-73. Epub 2015 Jul 3.

Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, 28049 Madrid, Spain.

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July 2015

A G-quadruplex-binding macrodomain within the "SARS-unique domain" is essential for the activity of the SARS-coronavirus replication-transcription complex.

Authors:
Yuri Kusov Jinzhi Tan Enrique Alvarez Luis Enjuanes Rolf Hilgenfeld

Virology 2015 Oct 3;484:313-322. Epub 2015 Jul 3.

Institute of Biochemistry, Center for Structural and Cell Biology in Medicine, University of Lübeck, Lübeck, Germany; German Center for Infection Research (DZIF), Hamburg - Lübeck - Borstel Site, University of Lübeck, Germany. Electronic address:

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October 2015

Virus Research. Foreword. Nidoviruses II.

Authors:
Matt Frieman Isabel Sola Luis Enjuanes

Virus Res 2015 Apr;202:1-2

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April 2015

Identification of a gamma interferon-activated inhibitor of translation-like RNA motif at the 3' end of the transmissible gastroenteritis coronavirus genome modulating innate immune response.

Authors:
Silvia Marquez-Jurado Aitor Nogales Sonia Zuñiga Luis Enjuanes Fernando Almazán

mBio 2015 Mar 10;6(2):e00105. Epub 2015 Mar 10.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain.

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March 2015

Engineering infectious cDNAs of coronavirus as bacterial artificial chromosomes.

Authors:
Fernando Almazán Silvia Márquez-Jurado Aitor Nogales Luis Enjuanes

Methods Mol Biol 2015 ;1282:135-52

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin 3, Cantoblanco, Madrid, 28049, Spain.

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November 2015

Porcine aminopeptidase N mediated polarized infection by porcine epidemic diarrhea virus in target cells.

Authors:
Yingying Cong Xiaoxue Li Yunyun Bai Xiaonan Lv Georg Herrler Luis Enjuanes Xingdong Zhou Bo Qu Fandan Meng Chengcheng Cong Xiaofeng Ren Guangxing Li

Virology 2015 Apr 11;478:1-8. Epub 2015 Feb 11.

College of Veterinary Medicine, Northeast Agricultural University, Harbin 150030, China.

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April 2015

Severe acute respiratory syndrome coronaviruses with mutations in the E protein are attenuated and promising vaccine candidates.

Authors:
Jose A Regla-Nava Jose L Nieto-Torres Jose M Jimenez-Guardeño Raul Fernandez-Delgado Craig Fett Carlos Castaño-Rodríguez Stanley Perlman Luis Enjuanes Marta L DeDiego

J Virol 2015 Apr 21;89(7):3870-87. Epub 2015 Jan 21.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Darwin 3, Campus Universidad Autónoma de Madrid, Madrid, Spain.

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April 2015

Virus Research. Nidoviruses I. Foreword.

Authors:
Luis Enjuanes Isabel Sola Matthew B Frieman

Virus Res 2014 Dec;194:1-2

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December 2014

Reprint of: Coronavirus reverse genetic systems: infectious clones and replicons.

Authors:
Fernando Almazán Isabel Sola Sonia Zuñiga Silvia Marquez-Jurado Lucia Morales Martina Becares Luis Enjuanes

Virus Res 2014 Dec 26;194:67-75. Epub 2014 Sep 26.

Department of Molecular and Cell Biology. Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, C/ Darwin 3, Cantoblanco, 28049 Madrid, Spain. Electronic address:

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December 2014

The PDZ-binding motif of severe acute respiratory syndrome coronavirus envelope protein is a determinant of viral pathogenesis.

Authors:
Jose M Jimenez-Guardeño Jose L Nieto-Torres Marta L DeDiego Jose A Regla-Nava Raul Fernandez-Delgado Carlos Castaño-Rodriguez Luis Enjuanes

PLoS Pathog 2014 Aug 14;10(8):e1004320. Epub 2014 Aug 14.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Darwin 3, Campus Universidad Autónoma de Madrid, Madrid, Spain.

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August 2014

Antigenic structures stably expressed by recombinant TGEV-derived vectors.

Authors:
Martina Becares Carlos M Sanchez Isabel Sola Luis Enjuanes Sonia Zuñiga

Virology 2014 Sep 9;464-465:274-286. Epub 2014 Aug 9.

Centro Nacional de Biotecnología, CNB-CSIC, Department of Molecular and Cell Biology, Campus Universidad Autónoma de Madrid, Darwin 3, Madrid 28049, Spain.

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September 2014

Coronavirus virulence genes with main focus on SARS-CoV envelope gene.

Authors:
Marta L DeDiego Jose L Nieto-Torres Jose M Jimenez-Guardeño Jose A Regla-Nava Carlos Castaño-Rodriguez Raul Fernandez-Delgado Fernando Usera Luis Enjuanes

Virus Res 2014 Dec 2;194:124-37. Epub 2014 Aug 2.

Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autonoma de Madrid, Madrid, Spain. Electronic address:

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December 2014

Coronavirus reverse genetic systems: infectious clones and replicons.

Authors:
Fernando Almazán Isabel Sola Sonia Zuñiga Silvia Marquez-Jurado Lucia Morales Martina Becares Luis Enjuanes

Virus Res 2014 Aug 12;189:262-70. Epub 2014 Jun 12.

Department of Molecular and Cell Biology. Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, C/ Darwin 3, Cantoblanco, 28049 Madrid, Spain. Electronic address:

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August 2014

Severe acute respiratory syndrome coronavirus envelope protein ion channel activity promotes virus fitness and pathogenesis.

Authors:
Jose L Nieto-Torres Marta L DeDiego Carmina Verdiá-Báguena Jose M Jimenez-Guardeño Jose A Regla-Nava Raul Fernandez-Delgado Carlos Castaño-Rodriguez Antonio Alcaraz Jaume Torres Vicente M Aguilella Luis Enjuanes

PLoS Pathog 2014 May 1;10(5):e1004077. Epub 2014 May 1.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain.

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May 2014

Rapid generation of a mouse model for Middle East respiratory syndrome.

Authors:
Jincun Zhao Kun Li Christine Wohlford-Lenane Sudhakar S Agnihothram Craig Fett Jingxian Zhao Michael J Gale Ralph S Baric Luis Enjuanes Tom Gallagher Paul B McCray Stanley Perlman

Proc Natl Acad Sci U S A 2014 Apr 5;111(13):4970-5. Epub 2014 Mar 5.

Departments of Microbiology and Pediatrics, University of Iowa, Iowa City, IA 52240.

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April 2014

Development of a novel DNA-launched dengue virus type 2 infectious clone assembled in a bacterial artificial chromosome.

Authors:
Jose A Usme-Ciro Jaime A Lopera Luis Enjuanes Fernando Almazán Juan C Gallego-Gomez

Virus Res 2014 Feb 14;180:12-22. Epub 2013 Dec 14.

Molecular and Translational Medicine Group, Facultad de Medicina, Universidad de Antioquia, Calle 70 No. 52-21, Medellín, Colombia; Viral Vector Core & Gene Therapy, Neuroscience Group, Facultad de Medicina, Sede de Investigación Universitaria-SIU, Universidad de Antioquia, Calle 70 No. 52-21, Medellín, Colombia. Electronic address:

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February 2014

Inhibition of NF-κB-mediated inflammation in severe acute respiratory syndrome coronavirus-infected mice increases survival.

Authors:
Marta L DeDiego Jose L Nieto-Torres Jose A Regla-Nava Jose M Jimenez-Guardeño Raul Fernandez-Delgado Craig Fett Carlos Castaño-Rodriguez Stanley Perlman Luis Enjuanes

J Virol 2014 Jan 6;88(2):913-24. Epub 2013 Nov 6.

Department of Molecular and Cell Biology, National Center of Biotechnology, Campus Universidad Autónoma de Madrid, Madrid, Spain.

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January 2014

A novel porcine reproductive and respiratory syndrome virus vector system that stably expresses enhanced green fluorescent protein as a separate transcription unit.

Authors:
Chengbao Wang Baicheng Huang Ning Kong Qiongyi Li Yuping Ma Zhijun Li Jiming Gao Chong Zhang Xiangpeng Wang Chao Liang Lu Dang Shuqi Xiao Yang Mu Qin Zhao Yani Sun Fernando Almazan Luis Enjuanes En-Min Zhou

Vet Res 2013 Oct 31;44:104. Epub 2013 Oct 31.

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Northwest A&F University, No, 22 Xinong Road, Yangling, Shaanxi 712100, China.

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October 2013

Engineering a replication-competent, propagation-defective Middle East respiratory syndrome coronavirus as a vaccine candidate.

Authors:
Fernando Almazán Marta L DeDiego Isabel Sola Sonia Zuñiga Jose L Nieto-Torres Silvia Marquez-Jurado German Andrés Luis Enjuanes

mBio 2013 Sep 10;4(5):e00650-13. Epub 2013 Sep 10.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spain.

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September 2013

Transmissible gastroenteritis coronavirus genome packaging signal is located at the 5' end of the genome and promotes viral RNA incorporation into virions in a replication-independent process.

Authors:
Lucia Morales Pedro A Mateos-Gomez Carmen Capiscol Lorena del Palacio Luis Enjuanes Isabel Sola

J Virol 2013 Nov 21;87(21):11579-90. Epub 2013 Aug 21.

Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus de la Universidad Autonoma de Madrid, Madrid, Spain.

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November 2013

The replication of a mouse adapted SARS-CoV in a mouse cell line stably expressing the murine SARS-CoV receptor mACE2 efficiently induces the expression of proinflammatory cytokines.

Authors:
Jose A Regla-Nava Jose M Jimenez-Guardeño Jose L Nieto-Torres Thomas M Gallagher Luis Enjuanes Marta L DeDiego

J Virol Methods 2013 Nov 1;193(2):639-46. Epub 2013 Aug 1.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Darwin 3, Campus Universidad Autónoma de Madrid, 28049 Madrid, Spain.

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November 2013

Alphacoronavirus protein 7 modulates host innate immune response.

Authors:
Jazmina L G Cruz Martina Becares Isabel Sola Juan Carlos Oliveros Luis Enjuanes Sonia Zúñiga

J Virol 2013 Sep 3;87(17):9754-67. Epub 2013 Jul 3.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología, CNB-CSIC, Campus Universidad Autónoma de Madrid, Madrid, Spain.

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September 2013

Analysis of SARS-CoV E protein ion channel activity by tuning the protein and lipid charge.

Authors:
Carmina Verdiá-Báguena Jose L Nieto-Torres Antonio Alcaraz Marta L Dediego Luis Enjuanes Vicente M Aguilella

Biochim Biophys Acta 2013 Sep 18;1828(9):2026-31. Epub 2013 May 18.

Department of Physics, Laboratory of Molecular Biophysics, Universitat Jaume I, 12071 Castellón, Spain.

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September 2013

Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study Group.

Authors:
Raoul J de Groot Susan C Baker Ralph S Baric Caroline S Brown Christian Drosten Luis Enjuanes Ron A M Fouchier Monica Galiano Alexander E Gorbalenya Ziad A Memish Stanley Perlman Leo L M Poon Eric J Snijder Gwen M Stephens Patrick C Y Woo Ali M Zaki Maria Zambon John Ziebuhr

J Virol 2013 Jul 15;87(14):7790-2. Epub 2013 May 15.

Division of Virology, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

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July 2013

Complete protection against severe acute respiratory syndrome coronavirus-mediated lethal respiratory disease in aged mice by immunization with a mouse-adapted virus lacking E protein.

Authors:
Craig Fett Marta L DeDiego Jose A Regla-Nava Luis Enjuanes Stanley Perlman

J Virol 2013 Jun 10;87(12):6551-9. Epub 2013 Apr 10.

Department of Microbiology, University of Iowa, Iowa City, Iowa, USA.

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June 2013

The use of transient expression systems for the rapid production of virus-like particles in plants.

Authors:
Eva C Thuenemann Paolo Lenzi Andrew J Love Michael Taliansky Martina Bécares Sonia Zuñiga Luis Enjuanes Gergana G Zahmanova Ivan N Minkov Slavica Matić Emanuela Noris Ann Meyers Alta Hattingh Edward P Rybicki Oleg I Kiselev Nikolai V Ravin Michael A Eldarov Konstantin G Skryabin George P Lomonossoff

Curr Pharm Des 2013 ;19(31):5564-73

Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK.

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March 2014

Long-distance RNA-RNA interactions in the coronavirus genome form high-order structures promoting discontinuous RNA synthesis during transcription.

Authors:
Pedro A Mateos-Gomez Lucia Morales Sonia Zuñiga Luis Enjuanes Isabel Sola

J Virol 2013 Jan 10;87(1):177-86. Epub 2012 Oct 10.

Department of Molecular and Cell Biology, National Center of Biotechnology, Campus de la Universidad Autonoma de Madrid, Madrid, Spain.

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January 2013

Combined action of type I and type III interferon restricts initial replication of severe acute respiratory syndrome coronavirus in the lung but fails to inhibit systemic virus spread.

Authors:
Tanel Mahlakõiv Daniel Ritz Markus Mordstein Marta L DeDiego Luis Enjuanes Marcel A Müller Christian Drosten Peter Staeheli

J Gen Virol 2012 Dec 5;93(Pt 12):2601-2605. Epub 2012 Sep 5.

Department of Virology, University of Freiburg, 79104 Freiburg, Germany.

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December 2012

Structural bases of coronavirus attachment to host aminopeptidase N and its inhibition by neutralizing antibodies.

Authors:
Juan Reguera César Santiago Gaurav Mudgal Desiderio Ordoño Luis Enjuanes José M Casasnovas

PLoS Pathog 2012 2;8(8):e1002859. Epub 2012 Aug 2.

Centro Nacional de Biotecnología, CNB-CSIC, Madrid, Spain.

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December 2012

Severe acute respiratory syndrome coronavirus nsp1 facilitates efficient propagation in cells through a specific translational shutoff of host mRNA.

Authors:
Tomohisa Tanaka Wataru Kamitani Marta L DeDiego Luis Enjuanes Yoshiharu Matsuura

J Virol 2012 Oct 1;86(20):11128-37. Epub 2012 Aug 1.

Global COE Program, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.

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October 2012

Coronavirus E protein forms ion channels with functionally and structurally-involved membrane lipids.

Authors:
Carmina Verdiá-Báguena Jose L Nieto-Torres Antonio Alcaraz Marta L DeDiego Jaume Torres Vicente M Aguilella Luis Enjuanes

Virology 2012 Oct 24;432(2):485-94. Epub 2012 Jul 24.

Department of Physics, Laboratory of Molecular Biophysics, Universitat Jaume I, 12071 Castellón, Spain.

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October 2012

Severe acute respiratory syndrome coronavirus replication inhibitor that interferes with the nucleic acid unwinding of the viral helicase.

Authors:
Adeyemi O Adedeji Kamalendra Singh Nicholas E Calcaterra Marta L DeDiego Luis Enjuanes Susan Weiss Stefan G Sarafianos

Antimicrob Agents Chemother 2012 Sep 25;56(9):4718-28. Epub 2012 Jun 25.

Christopher S. Bond Life Sciences Center, Department of Molecular Microbiology and Immunology, University of Missouri School of Medicine, Columbia, Missouri, USA.

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September 2012

Molecular characterization of feline infectious peritonitis virus strain DF-2 and studies of the role of ORF3abc in viral cell tropism.

Authors:
Ádám Bálint Attila Farsang Zoltán Zádori Ákos Hornyák László Dencso Fernando Almazán Luis Enjuanes Sándor Belák

J Virol 2012 Jun 21;86(11):6258-67. Epub 2012 Mar 21.

Department of Virology, Agricultural Office Veterinary Diagnostic Directorate, Budapest, Hungary.

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June 2012

Transmissible gastroenteritis coronavirus RNA-dependent RNA polymerase and nonstructural proteins 2, 3, and 8 are incorporated into viral particles.

Authors:
Aitor Nogales Silvia Márquez-Jurado Carmen Galán Luis Enjuanes Fernando Almazán

J Virol 2012 Jan 16;86(2):1261-6. Epub 2011 Nov 16.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spain.

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January 2012

Severe acute respiratory syndrome coronavirus envelope protein regulates cell stress response and apoptosis.

Authors:
Marta L DeDiego Jose L Nieto-Torres Jose M Jiménez-Guardeño Jose A Regla-Nava Enrique Alvarez Juan Carlos Oliveros Jincun Zhao Craig Fett Stanley Perlman Luis Enjuanes

PLoS Pathog 2011 Oct 20;7(10):e1002315. Epub 2011 Oct 20.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain.

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October 2011

The sialic acid binding activity of the S protein facilitates infection by porcine transmissible gastroenteritis coronavirus.

Authors:
Christel Schwegmann-Wessels Sandra Bauer Christine Winter Luis Enjuanes Hubert Laude Georg Herrler

Virol J 2011 Sep 12;8:435. Epub 2011 Sep 12.

Institute for Virology, University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany.

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September 2011

Gene N proximal and distal RNA motifs regulate coronavirus nucleocapsid mRNA transcription.

Authors:
Pedro A Mateos-Gómez Sonia Zuñiga Lorena Palacio Luis Enjuanes Isabel Sola

J Virol 2011 Sep 29;85(17):8968-80. Epub 2011 Jun 29.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología, Darwin 3, Campus de la Universidad Autonoma de Madrid, 28049 Madrid, Spain.

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September 2011

Coronavirus gene 7 counteracts host defenses and modulates virus virulence.

Authors:
Jazmina L G Cruz Isabel Sola Martina Becares Berta Alberca Joan Plana Luis Enjuanes Sonia Zuñiga

PLoS Pathog 2011 Jun 9;7(6):e1002090. Epub 2011 Jun 9.

Centro Nacional de Biotecnología, CNB, CSIC, Department of Molecular and Cell Biology, Darwin 3, Campus Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spain.

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June 2011

RNA virus replication, transcription and recombination.

Authors:
K Andrew White Luis Enjuanes Ben Berkhout

RNA Biol 2011 Mar-Apr;8(2):182-3. Epub 2011 Mar 1.

Department of Biology, York University, Toronto, Ontario, Canada.

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November 2011

Interference of ribosomal frameshifting by antisense peptide nucleic acids suppresses SARS coronavirus replication.

Authors:
Dae-Gyun Ahn Wooseong Lee Jin-Kyu Choi Seong-Jun Kim Ewan P Plant Fernando Almazán Deborah R Taylor Luis Enjuanes Jong-Won Oh

Antiviral Res 2011 Jul 23;91(1):1-10. Epub 2011 Apr 23.

Department of Biotechnology and Translational Research Center for Protein Function Control, Yonsei University, Seoul, Republic of Korea.

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July 2011

Subcellular location and topology of severe acute respiratory syndrome coronavirus envelope protein.

Authors:
Jose L Nieto-Torres Marta L Dediego Enrique Alvarez Jose M Jiménez-Guardeño Jose A Regla-Nava Mercedes Llorente Leonor Kremer Shen Shuo Luis Enjuanes

Virology 2011 Jul 27;415(2):69-82. Epub 2011 Apr 27.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Darwin 3, Campus Universidad Autónoma de Madrid, 28049 Madrid, Spain.

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July 2011

Immunogenic characterization and epitope mapping of transmissible gastroenteritis virus RNA dependent RNA polymerase.

Authors:
Aitor Nogales Carmen Galán Silvia Márquez-Jurado Mónica García-Gallo Leonor Kremer Luis Enjuanes Fernando Almazán

J Virol Methods 2011 Jul 12;175(1):7-13. Epub 2011 Apr 12.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), C/ Darwin 3, Cantoblanco, 28049 Madrid, Spain.

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July 2011

The polypyrimidine tract-binding protein affects coronavirus RNA accumulation levels and relocalizes viral RNAs to novel cytoplasmic domains different from replication-transcription sites.

Authors:
Isabel Sola Carmen Galán Pedro A Mateos-Gómez Lorena Palacio Sonia Zúñiga Jazmina L Cruz Fernando Almazán Luis Enjuanes

J Virol 2011 May 16;85(10):5136-49. Epub 2011 Mar 16.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología, CSIC, Darwin 3, Cantoblanco, 28049 Madrid, Spain.

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May 2011

Structure and functional relevance of a transcription-regulating sequence involved in coronavirus discontinuous RNA synthesis.

Authors:
David Dufour Pedro A Mateos-Gomez Luis Enjuanes José Gallego Isabel Sola

J Virol 2011 May 9;85(10):4963-73. Epub 2011 Mar 9.

Centro de Investigación Príncipe Felipe, Avda. Autopista del Saler 16, 46012 Valencia, Spain.

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May 2011

RNA-RNA and RNA-protein interactions in coronavirus replication and transcription.

Authors:
Isabel Sola Pedro A Mateos-Gomez Fernando Almazan Sonia Zuñiga Luis Enjuanes

RNA Biol 2011 Mar-Apr;8(2):237-48. Epub 2011 Mar 1.

Department of Molecular and Cell Biology, CNB, CSIC, Cantoblanco, Madrid, Spain.

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November 2011

Antigenic modules in the N-terminal S1 region of the transmissible gastroenteritis virus spike protein.

Authors:
Juan Reguera Desiderio Ordoño César Santiago Luis Enjuanes José M Casasnovas

J Gen Virol 2011 May 12;92(Pt 5):1117-1126. Epub 2011 Jan 12.

Department of Macromolecule Structure, Centro Nacional de Biotecnologia, CSIC, Campus Universidad Autónoma, Darwin 3, 28049 Madrid, Spain.

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May 2011

Transmissible gastroenteritis virus (TGEV)-based vectors with engineered murine tropism express the rotavirus VP7 protein and immunize mice against rotavirus.

Authors:
Juan Manuel Ribes Javier Ortego Juan Ceriani Rebeca Montava Luis Enjuanes Javier Buesa

Virology 2011 Feb 21;410(1):107-18. Epub 2010 Nov 21.

Department of Microbiology and Ecology, School of Medicine, University of Valencia, Avda. Blasco Ibáñez, 17, 46010 Valencia, Spain.

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February 2011

Cholesterol is important for a post-adsorption step in the entry process of transmissible gastroenteritis virus.

Authors:
Jiechao Yin Joerg Glende Christel Schwegmann-Wessels Luis Enjuanes Georg Herrler Xiaofeng Ren

Antiviral Res 2010 Dec 14;88(3):311-6. Epub 2010 Oct 14.

Northeast Agricultural University, Harbin, China.

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December 2010

Vectored vaccines to protect against PRRSV.

Authors:
Jazmina L G Cruz Sonia Zúñiga Martina Bécares Isabel Sola Juan E Ceriani Sandra Juanola Juan Plana Luis Enjuanes

Virus Res 2010 Dec 25;154(1-2):150-60. Epub 2010 Jun 25.

Centro Nacional de Biotecnología, CSIC, Department of Molecular and Cell Biology, Campus Universidad Autónoma de Madrid, Darwin 3, 28049 Madrid, Spain.

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December 2010

Rapid differentiation of vaccine strain and Chinese field strains of transmissible gastroenteritis virus by restriction fragment length polymorphism of the N gene.

Authors:
Chengbao Wang Jianfei Chen Hongyan Shi Hua-Ji Qiu Fei Xue Shengwang Liu Changming Liu Yuanmao Zhu Fernando Almazán Luis Enjuanes Li Feng

Virus Genes 2010 Aug 23;41(1):47-58. Epub 2010 Apr 23.

Division of Swine Infectious Diseases, National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 427 Maduan Street, Nangang District, Harbin, 150001, People's Republic of China.

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August 2010

The envelope protein of severe acute respiratory syndrome coronavirus interacts with the non-structural protein 3 and is ubiquitinated.

Authors:
Enrique Alvarez Marta L DeDiego Jose L Nieto-Torres Jose M Jiménez-Guardeño Laura Marcos-Villar Luis Enjuanes

Virology 2010 Jul 20;402(2):281-91. Epub 2010 Apr 20.

Centro Nacional de Biotecnología (CNB), CSIC, Darwin 3, Campus Universidad Autónoma de Madrid, 28049 Madrid, Spain.

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July 2010

Molecular characterization of a Chinese vaccine strain of transmissible gastroenteritis virus: mutations that may contribute to attenuation.

Authors:
Chengbao Wang Jianfei Chen Hongyan Shi Huaji Qiu Fei Xue Changming Liu Yuanmao Zhu Shengwang Liu Fernando Almazán Luis Enjuanes Li Feng

Virus Genes 2010 Jun 13;40(3):403-9. Epub 2010 Mar 13.

Division of Swine Infectious Diseases, National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of the Chinese Academy of Agricultural Sciences, Nangang District, Harbin 150001, People's Republic of China.

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June 2010

Immunization with an attenuated severe acute respiratory syndrome coronavirus deleted in E protein protects against lethal respiratory disease.

Authors:
Jason Netland Marta L DeDiego Jincun Zhao Craig Fett Enrique Álvarez José L Nieto-Torres Luis Enjuanes Stanley Perlman

Virology 2010 Mar 27;399(1):120-128. Epub 2010 Jan 27.

Interdisciplinary Program in Immunology, University of Iowa, Iowa City, IA 52242; Department of Microbiology, University of Iowa, Iowa City, IA 52242. Electronic address:

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March 2010

Coronavirus nucleocapsid protein facilitates template switching and is required for efficient transcription.

Authors:
Sonia Zúñiga Jazmina L G Cruz Isabel Sola Pedro A Mateos-Gómez Lorena Palacio Luis Enjuanes

J Virol 2010 Feb 2;84(4):2169-75. Epub 2009 Dec 2.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología, CSIC, Darwin, 3, Ciudad Universitaria de Cantoblanco, 28049 Madrid, Spain.

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February 2010

Host cell proteins interacting with the 3' end of TGEV coronavirus genome influence virus replication.

Authors:
Carmen Galán Isabel Sola Aitor Nogales Benjamin Thomas Alexandre Akoulitchev Luis Enjuanes Fernando Almazán

Virology 2009 Sep 5;391(2):304-14. Epub 2009 Jul 5.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología, CSIC, C/Darwin 3, Cantoblanco, 28049 Madrid, Spain.

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September 2009

Comparison of vesicular stomatitis virus pseudotyped with the S proteins from a porcine and a human coronavirus.

Authors:
Christel Schwegmann-Weßels Jörg Glende Xiaofeng Ren Xiuxia Qu Hongkui Deng Luis Enjuanes Georg Herrler

J Gen Virol 2009 Jul 4;90(Pt 7):1724-1729. Epub 2009 Mar 4.

Institute of Virology, University of Veterinary Medicine Hannover, Hannover, Germany.

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July 2009

Severe acute respiratory syndrome coronavirus protein 6 is required for optimal replication.

Authors:
Jincun Zhao Ana Falcón Haixia Zhou Jason Netland Luis Enjuanes Pilar Pérez Breña Stanley Perlman

J Virol 2009 Mar 17;83(5):2368-73. Epub 2008 Dec 17.

Department of Microbiology, University of Iowa, Iowa City, Iowa 52242, USA.

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March 2009

Engineering infectious cDNAs of coronavirus as bacterial artificial chromosomes.

Authors:
Fernando Almazán Carmen Galán Luis Enjuanes

Methods Mol Biol 2008 ;454:275-91

Centro Nacional de Biotecnología, CSIC, Department of Molecular and Cell Biology, Cantoblanco, Madrid, Spain.

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March 2009

Recombinant canine coronaviruses related to transmissible gastroenteritis virus of Swine are circulating in dogs.

Authors:
Nicola Decaro Viviana Mari Marco Campolo Alessio Lorusso Michele Camero Gabriella Elia Vito Martella Paolo Cordioli Luis Enjuanes Canio Buonavoglia

J Virol 2009 Feb 26;83(3):1532-7. Epub 2008 Nov 26.

Department of Public Health and Animal Sciences, Faculty of Veterinary Medicine, Valenzano (Bari), Italy.

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February 2009

Genome-wide analysis of protein-protein interactions and involvement of viral proteins in SARS-CoV replication.

Authors:
Ji'an Pan Xiaoxue Peng Yajing Gao Zhilin Li Xiaolu Lu Yingzhao Chen Musarat Ishaq Dan Liu Marta L Dediego Luis Enjuanes Deyin Guo

PLoS One 2008 Oct 1;3(10):e3299. Epub 2008 Oct 1.

State Key Laboratory of Virology and Modern Virology Research Centre, College of Life Sciences, Wuhan University, Wuhan, People's Republic of China.

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October 2008

Role of RNA chaperones in virus replication.

Authors:
Sonia Zúñiga Isabel Sola Jazmina L G Cruz Luis Enjuanes

Virus Res 2009 Feb 8;139(2):253-66. Epub 2008 Aug 8.

Centro Nacional de Biotecnología, CSIC, Department of Molecular and Cell Biology, Campus Universitario de Cantoblanco, Darwin 3, 28049 Madrid, Spain.

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February 2009

A live attenuated severe acute respiratory syndrome coronavirus is immunogenic and efficacious in golden Syrian hamsters.

Authors:
Elaine W Lamirande Marta L DeDiego Anjeanette Roberts Jadon P Jackson Enrique Alvarez Tim Sheahan Wun-Ju Shieh Sherif R Zaki Ralph Baric Luis Enjuanes Kanta Subbarao

J Virol 2008 Aug 7;82(15):7721-4. Epub 2008 May 7.

Laboratory of Infectious Diseases, NIAID, NIH, Bethesda, MD 20892, USA.

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August 2008

Pathogenicity of severe acute respiratory coronavirus deletion mutants in hACE-2 transgenic mice.

Authors:
Marta L Dediego Lecia Pewe Enrique Alvarez Maria Teresa Rejas Stanley Perlman Luis Enjuanes

Virology 2008 Jul 2;376(2):379-89. Epub 2008 May 2.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CSIC), Campus Universidad Autónoma, Darwin 3, Cantoblanco, 28049 Madrid, Spain.

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July 2008

Identification of a coronavirus transcription enhancer.

Authors:
José L Moreno Sonia Zúñiga Luis Enjuanes Isabel Sola

J Virol 2008 Apr 13;82(8):3882-93. Epub 2008 Feb 13.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología, CSIC, C/Darwin 3, Cantoblanco, 28049 Madrid, Spain.

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April 2008

Absence of E protein arrests transmissible gastroenteritis coronavirus maturation in the secretory pathway.

Authors:
Javier Ortego Juan E Ceriani Cristina Patiño Juan Plana Luis Enjuanes

Virology 2007 Nov 10;368(2):296-308. Epub 2007 Aug 10.

Centro Nacional de Biotecnología, CSIC, Department of Molecular and Cell Biology, Campus Universidad Autónoma, Darwin 3, Cantoblanco, 28049 Madrid, Spain.

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November 2007

Vaccines to prevent severe acute respiratory syndrome coronavirus-induced disease.

Authors:
Luis Enjuanes Marta L Dediego Enrique Alvarez Damon Deming Tim Sheahan Ralph Baric

Virus Res 2008 Apr 9;133(1):45-62. Epub 2007 Apr 9.

Centro Nacional de Biotecnología (CNB), CSIC, Campus Universidad Autónoma, Cantoblanco, Darwin 3, 28049 Madrid, Spain.

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April 2008

An antibody derivative expressed from viral vectors passively immunizes pigs against transmissible gastroenteritis virus infection when supplied orally in crude plant extracts.

Authors:
Wendy Monger Josefa M Alamillo Isabel Sola Yolande Perrin Marco Bestagno Oscar R Burrone Patricia Sabella Joan Plana-Duran Luis Enjuanes Juan A Garcia George P Lomonossoff

Plant Biotechnol J 2006 Nov;4(6):623-31

John Innes Centre, Colney Lane, Norwich NR4 7UH, UK.

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November 2006

Recombinant dimeric small immunoproteins neutralize transmissible gastroenteritis virus infectivity efficiently in vitro and confer passive immunity in vivo.

Authors:
Marco Bestagno Isabel Sola Eliana Dallegno Patricia Sabella Monica Poggianella Juan Plana-Durán Luis Enjuanes Oscar R Burrone

J Gen Virol 2007 Jan;88(Pt 1):187-195

International Centre for Genetic Engineering and Biotechnology, AREA Science Park, Padriciano 99, 34012 Trieste, Italy.

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January 2007

A severe acute respiratory syndrome coronavirus that lacks the E gene is attenuated in vitro and in vivo.

Authors:
Marta L DeDiego Enrique Alvarez Fernando Almazán María Teresa Rejas Elaine Lamirande Anjeanette Roberts Wun-Ju Shieh Sherif R Zaki Kanta Subbarao Luis Enjuanes

J Virol 2007 Feb 15;81(4):1701-13. Epub 2006 Nov 15.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología, CSIC, Darwin 3, Campus Universidad Autónoma, Cantoblanco, 28049 Madrid, Spain.

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February 2007

Identification of essential genes as a strategy to select a SARS candidate vaccine using a SARS-CoV infectious cDNA.

Authors:
Fernando Almazán Marta L DeDiego Carmen Galán Enrique Alvarez Luis Enjuanes

Adv Exp Med Biol 2006 ;581:579-83

Centro Nacional de Biotecnología, CSIC, Madrid, Spain.

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December 2006

Differential role of N-terminal polyprotein processing in coronavirus genome replication and minigenome amplification.

Authors:
Carmen Galán Luis Enjuanes Fernando Almazán

Adv Exp Med Biol 2006 ;581:79-83

Centro Nacional de Biotecnología, CSIC, Madrid, Spain.

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December 2006

Regulation of coronavirus transcription: viral and cellular proteins interacting with transcription-regulating sequences.

Authors:
Sonia Zúñiga Isabel Sola Jose L Moreno Sara Alonso Luis Enjuanes

Adv Exp Med Biol 2006 ;581:31-5

Centro Nacional de Biotecnología, CSIC, Madrid, Spain.

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December 2006

Biochemical aspects of coronavirus replication.

Authors:
Luis Enjuanes Fernando Almazán Isabel Sola Sonia Zúñiga Enrique Alvarez Juan Reguera Carmen Capiscol

Adv Exp Med Biol 2006 ;581:13-24

Centro Nacional de Biotecnología, CSIC, Madrid, Spain.

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December 2006

Use of virus vectors for the expression in plants of active full-length and single chain anti-coronavirus antibodies.

Authors:
Josefa M Alamillo Wendy Monger Isabel Sola Beatriz García Yolande Perrin Marco Bestagno Oscar R Burrone Patricia Sabella Joan Plana-Durán Luis Enjuanes George P Lomonossoff Juan A García

Biotechnol J 2006 Oct;1(10):1103-11

Centro Nacional de Biotecnología, Campus Universidad Autónoma, Madrid, Spain.

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October 2006

Coronavirus nucleocapsid protein is an RNA chaperone.

Authors:
Sonia Zúñiga Isabel Sola Jose L Moreno Patricia Sabella Juan Plana-Durán Luis Enjuanes

Virology 2007 Jan 18;357(2):215-27. Epub 2006 Sep 18.

Centro Nacional de Biotecnología, CSIC, Department of Molecular and Cell Biology, Campus Universidad Autónoma, Darwin 3, Cantoblanco, 28049 Madrid, Spain.

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January 2007

Construction of a severe acute respiratory syndrome coronavirus infectious cDNA clone and a replicon to study coronavirus RNA synthesis.

Authors:
Fernando Almazán Marta L Dediego Carmen Galán David Escors Enrique Alvarez Javier Ortego Isabel Sola Sonia Zuñiga Sara Alonso Jose L Moreno Aitor Nogales Carmen Capiscol Luis Enjuanes

J Virol 2006 Nov 23;80(21):10900-6. Epub 2006 Aug 23.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología, CSIC, Darwin 3, Campus Universidad Autónoma, Cantoblanco, 28049 Madrid, Spain.

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November 2006

Methods for preparation of low abundance glycoproteins from mammalian cell supernatants.

Authors:
Desiderio Ordoño Luis Enjuanes José M Casasnovas

Int J Biol Macromol 2006 Aug 2;39(1-3):151-6. Epub 2006 Jun 2.

Centro Nacional de Biotecnologia, CSIC, Campus Universidad Autonoma, 28049 Madrid, Spain.

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August 2006