Publications by authors named "Luis Enjuanes"

100Publications

Middle East Respiratory Syndrome Coronavirus Gene 5 Modulates Pathogenesis in Mice.

J Virol 2021 01 13;95(3). Epub 2021 Jan 13.

Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain

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January 2021

Minimum Determinants of Transmissible Gastroenteritis Virus Enteric Tropism Are Located in the N-Terminus of Spike Protein.

Pathogens 2019 Dec 18;9(1). Epub 2019 Dec 18.

Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin 3, 28049 Madrid, Spain.

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December 2019

Recombinant Chimeric Transmissible Gastroenteritis Virus (TGEV) - Porcine Epidemic Diarrhea Virus (PEDV) Virus Provides Protection against Virulent PEDV.

Viruses 2019 07 25;11(8). Epub 2019 Jul 25.

Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin 3, 28049 Madrid, Spain.

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July 2019

Adaptive Evolution of MERS-CoV to Species Variation in DPP4.

Cell Rep 2018 08;24(7):1730-1737

Laboratory of Virology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Hamilton, MT 59840, USA. Electronic address:

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August 2018

Erratum to: Role of transcription regulatory sequence in regulation of gene expression and replication of porcine reproductive and respiratory syndrome virus.

Vet Res 2017 09 20;48(1):54. Epub 2017 Sep 20.

Swine and Poultry Infectious Diseases Research Center (CRIPA) and Research Group on Infectious Diseases in Production Animals (GREMIP), Faculty of Veterinary Medicine, Université de Montréal, 3200 Sicotte, Saint-Hyacinthe, QC, J2S 2M2, Canada.

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September 2017

Role of transcription regulatory sequence in regulation of gene expression and replication of porcine reproductive and respiratory syndrome virus.

Vet Res 2017 08 10;48(1):41. Epub 2017 Aug 10.

Swine and Poultry Infectious Diseases Research Center (CRIPA) and Research Group on Infectious Diseases in Production Animals (GREMIP), Faculty of Veterinary Medicine, Université de Montréal, 3200 Sicotte, Saint-Hyacinthe, QC, J2S 2M2, Canada.

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August 2017

Generation of a DNA-Launched Reporter Replicon Based on Dengue Virus Type 2 as a Multipurpose Platform.

Intervirology 2016 23;59(5-6):275-282. Epub 2017 Jun 23.

Molecular and Translational Medicine Group, Facultad de Medicina, Universidad de Antioquia, Medellin, Colombia.

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June 2017

Allosteric inhibition of aminopeptidase N functions related to tumor growth and virus infection.

Sci Rep 2017 04 10;7:46045. Epub 2017 Apr 10.

Centro Nacional de Biotecnología (CNB-CSIC), Darwin 3, Campus Universidad Autónoma de Madrid, 28049 Madrid, Spain.

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April 2017

SARS-CoV-Encoded Small RNAs Contribute to Infection-Associated Lung Pathology.

Cell Host Microbe 2017 Mar 16;21(3):344-355. Epub 2017 Feb 16.

Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Madrid, 28049, Spain.

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March 2017

Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress Responses.

PLoS Pathog 2016 Oct 26;12(10):e1005982. Epub 2016 Oct 26.

Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

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October 2016

Virulence factors in porcine coronaviruses and vaccine design.

Virus Res 2016 12 7;226:142-151. Epub 2016 Jul 7.

Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin 3, Madrid, Spain. Electronic address:

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December 2016

Mutagenesis of Coronavirus nsp14 Reveals Its Potential Role in Modulation of the Innate Immune Response.

J Virol 2016 06 12;90(11):5399-5414. Epub 2016 May 12.

Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain.

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June 2016

Continuous and Discontinuous RNA Synthesis in Coronaviruses.

Annu Rev Virol 2015 Nov;2(1):265-88

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología-Consejo Superior de Investigaciones Científicas (CNB-CSIC), 28049 Madrid, Spain; email:

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November 2015

Identification of the Mechanisms Causing Reversion to Virulence in an Attenuated SARS-CoV for the Design of a Genetically Stable Vaccine.

PLoS Pathog 2015 Oct 29;11(10):e1005215. Epub 2015 Oct 29.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain.

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October 2015

Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome.

Virology 2015 Nov 29;485:330-9. Epub 2015 Aug 29.

Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, 28049 Madrid, Spain. Electronic address:

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November 2015

Relevance of Viroporin Ion Channel Activity on Viral Replication and Pathogenesis.

Viruses 2015 Jul 3;7(7):3552-73. Epub 2015 Jul 3.

Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autónoma de Madrid, 28049 Madrid, Spain.

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July 2015

A G-quadruplex-binding macrodomain within the "SARS-unique domain" is essential for the activity of the SARS-coronavirus replication-transcription complex.

Virology 2015 Oct 3;484:313-322. Epub 2015 Jul 3.

Institute of Biochemistry, Center for Structural and Cell Biology in Medicine, University of Lübeck, Lübeck, Germany; German Center for Infection Research (DZIF), Hamburg - Lübeck - Borstel Site, University of Lübeck, Germany. Electronic address:

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October 2015

Identification of a gamma interferon-activated inhibitor of translation-like RNA motif at the 3' end of the transmissible gastroenteritis coronavirus genome modulating innate immune response.

mBio 2015 Mar 10;6(2):e00105. Epub 2015 Mar 10.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain.

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March 2015

Engineering infectious cDNAs of coronavirus as bacterial artificial chromosomes.

Methods Mol Biol 2015 ;1282:135-52

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Darwin 3, Cantoblanco, Madrid, 28049, Spain.

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November 2015

Severe acute respiratory syndrome coronaviruses with mutations in the E protein are attenuated and promising vaccine candidates.

J Virol 2015 Apr 21;89(7):3870-87. Epub 2015 Jan 21.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Darwin 3, Campus Universidad Autónoma de Madrid, Madrid, Spain.

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April 2015

Reprint of: Coronavirus reverse genetic systems: infectious clones and replicons.

Virus Res 2014 Dec 26;194:67-75. Epub 2014 Sep 26.

Department of Molecular and Cell Biology. Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, C/ Darwin 3, Cantoblanco, 28049 Madrid, Spain. Electronic address:

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December 2014

The PDZ-binding motif of severe acute respiratory syndrome coronavirus envelope protein is a determinant of viral pathogenesis.

PLoS Pathog 2014 Aug 14;10(8):e1004320. Epub 2014 Aug 14.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Darwin 3, Campus Universidad Autónoma de Madrid, Madrid, Spain.

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August 2014

Antigenic structures stably expressed by recombinant TGEV-derived vectors.

Virology 2014 Sep 9;464-465:274-286. Epub 2014 Aug 9.

Centro Nacional de Biotecnología, CNB-CSIC, Department of Molecular and Cell Biology, Campus Universidad Autónoma de Madrid, Darwin 3, Madrid 28049, Spain.

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September 2014

Coronavirus virulence genes with main focus on SARS-CoV envelope gene.

Virus Res 2014 Dec 2;194:124-37. Epub 2014 Aug 2.

Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus Universidad Autonoma de Madrid, Madrid, Spain. Electronic address:

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December 2014

Coronavirus reverse genetic systems: infectious clones and replicons.

Virus Res 2014 Aug 12;189:262-70. Epub 2014 Jun 12.

Department of Molecular and Cell Biology. Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, C/ Darwin 3, Cantoblanco, 28049 Madrid, Spain. Electronic address:

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August 2014

Rapid generation of a mouse model for Middle East respiratory syndrome.

Proc Natl Acad Sci U S A 2014 Apr 5;111(13):4970-5. Epub 2014 Mar 5.

Departments of Microbiology and Pediatrics, University of Iowa, Iowa City, IA 52240.

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April 2014

Development of a novel DNA-launched dengue virus type 2 infectious clone assembled in a bacterial artificial chromosome.

Virus Res 2014 Feb 14;180:12-22. Epub 2013 Dec 14.

Molecular and Translational Medicine Group, Facultad de Medicina, Universidad de Antioquia, Calle 70 No. 52-21, Medellín, Colombia; Viral Vector Core & Gene Therapy, Neuroscience Group, Facultad de Medicina, Sede de Investigación Universitaria-SIU, Universidad de Antioquia, Calle 70 No. 52-21, Medellín, Colombia. Electronic address:

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February 2014

Engineering a replication-competent, propagation-defective Middle East respiratory syndrome coronavirus as a vaccine candidate.

mBio 2013 Sep 10;4(5):e00650-13. Epub 2013 Sep 10.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spain.

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September 2013

Transmissible gastroenteritis coronavirus genome packaging signal is located at the 5' end of the genome and promotes viral RNA incorporation into virions in a replication-independent process.

J Virol 2013 Nov 21;87(21):11579-90. Epub 2013 Aug 21.

Department of Molecular and Cell Biology, National Center of Biotechnology (CNB-CSIC), Campus de la Universidad Autonoma de Madrid, Madrid, Spain.

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November 2013

The replication of a mouse adapted SARS-CoV in a mouse cell line stably expressing the murine SARS-CoV receptor mACE2 efficiently induces the expression of proinflammatory cytokines.

J Virol Methods 2013 Nov 1;193(2):639-46. Epub 2013 Aug 1.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Darwin 3, Campus Universidad Autónoma de Madrid, 28049 Madrid, Spain.

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November 2013

Alphacoronavirus protein 7 modulates host innate immune response.

J Virol 2013 Sep 3;87(17):9754-67. Epub 2013 Jul 3.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología, CNB-CSIC, Campus Universidad Autónoma de Madrid, Madrid, Spain.

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September 2013

Analysis of SARS-CoV E protein ion channel activity by tuning the protein and lipid charge.

Biochim Biophys Acta 2013 Sep 18;1828(9):2026-31. Epub 2013 May 18.

Department of Physics, Laboratory of Molecular Biophysics, Universitat Jaume I, 12071 Castellón, Spain.

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September 2013

Long-distance RNA-RNA interactions in the coronavirus genome form high-order structures promoting discontinuous RNA synthesis during transcription.

J Virol 2013 Jan 10;87(1):177-86. Epub 2012 Oct 10.

Department of Molecular and Cell Biology, National Center of Biotechnology, Campus de la Universidad Autonoma de Madrid, Madrid, Spain.

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January 2013

Severe acute respiratory syndrome coronavirus nsp1 facilitates efficient propagation in cells through a specific translational shutoff of host mRNA.

J Virol 2012 Oct 1;86(20):11128-37. Epub 2012 Aug 1.

Global COE Program, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan.

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October 2012

Coronavirus E protein forms ion channels with functionally and structurally-involved membrane lipids.

Virology 2012 Oct 24;432(2):485-94. Epub 2012 Jul 24.

Department of Physics, Laboratory of Molecular Biophysics, Universitat Jaume I, 12071 Castellón, Spain.

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October 2012

Severe acute respiratory syndrome coronavirus replication inhibitor that interferes with the nucleic acid unwinding of the viral helicase.

Antimicrob Agents Chemother 2012 Sep 25;56(9):4718-28. Epub 2012 Jun 25.

Christopher S. Bond Life Sciences Center, Department of Molecular Microbiology and Immunology, University of Missouri School of Medicine, Columbia, Missouri, USA.

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September 2012

Transmissible gastroenteritis coronavirus RNA-dependent RNA polymerase and nonstructural proteins 2, 3, and 8 are incorporated into viral particles.

J Virol 2012 Jan 16;86(2):1261-6. Epub 2011 Nov 16.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spain.

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January 2012

Severe acute respiratory syndrome coronavirus envelope protein regulates cell stress response and apoptosis.

PLoS Pathog 2011 Oct 20;7(10):e1002315. Epub 2011 Oct 20.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Campus Universidad Autónoma de Madrid, Madrid, Spain.

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October 2011

The sialic acid binding activity of the S protein facilitates infection by porcine transmissible gastroenteritis coronavirus.

Virol J 2011 Sep 12;8:435. Epub 2011 Sep 12.

Institute for Virology, University of Veterinary Medicine Hannover, Bünteweg 17, 30559 Hannover, Germany.

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September 2011

Gene N proximal and distal RNA motifs regulate coronavirus nucleocapsid mRNA transcription.

J Virol 2011 Sep 29;85(17):8968-80. Epub 2011 Jun 29.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología, Darwin 3, Campus de la Universidad Autonoma de Madrid, 28049 Madrid, Spain.

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September 2011

Coronavirus gene 7 counteracts host defenses and modulates virus virulence.

PLoS Pathog 2011 Jun 9;7(6):e1002090. Epub 2011 Jun 9.

Centro Nacional de Biotecnología, CNB, CSIC, Department of Molecular and Cell Biology, Darwin 3, Campus Universidad Autónoma de Madrid, Cantoblanco, Madrid, Spain.

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June 2011

RNA virus replication, transcription and recombination.

RNA Biol 2011 Mar-Apr;8(2):182-3. Epub 2011 Mar 1.

Department of Biology, York University, Toronto, Ontario, Canada.

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November 2011

Interference of ribosomal frameshifting by antisense peptide nucleic acids suppresses SARS coronavirus replication.

Antiviral Res 2011 Jul 23;91(1):1-10. Epub 2011 Apr 23.

Department of Biotechnology and Translational Research Center for Protein Function Control, Yonsei University, Seoul, Republic of Korea.

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July 2011

Subcellular location and topology of severe acute respiratory syndrome coronavirus envelope protein.

Virology 2011 Jul 27;415(2):69-82. Epub 2011 Apr 27.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), Darwin 3, Campus Universidad Autónoma de Madrid, 28049 Madrid, Spain.

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July 2011

Immunogenic characterization and epitope mapping of transmissible gastroenteritis virus RNA dependent RNA polymerase.

J Virol Methods 2011 Jul 12;175(1):7-13. Epub 2011 Apr 12.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CNB-CSIC), C/ Darwin 3, Cantoblanco, 28049 Madrid, Spain.

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July 2011

Structure and functional relevance of a transcription-regulating sequence involved in coronavirus discontinuous RNA synthesis.

J Virol 2011 May 9;85(10):4963-73. Epub 2011 Mar 9.

Centro de Investigación Príncipe Felipe, Avda. Autopista del Saler 16, 46012 Valencia, Spain.

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May 2011

RNA-RNA and RNA-protein interactions in coronavirus replication and transcription.

RNA Biol 2011 Mar-Apr;8(2):237-48. Epub 2011 Mar 1.

Department of Molecular and Cell Biology, CNB, CSIC, Cantoblanco, Madrid, Spain.

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November 2011

Antigenic modules in the N-terminal S1 region of the transmissible gastroenteritis virus spike protein.

J Gen Virol 2011 May 12;92(Pt 5):1117-1126. Epub 2011 Jan 12.

Department of Macromolecule Structure, Centro Nacional de Biotecnologia, CSIC, Campus Universidad Autónoma, Darwin 3, 28049 Madrid, Spain.

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May 2011

Transmissible gastroenteritis virus (TGEV)-based vectors with engineered murine tropism express the rotavirus VP7 protein and immunize mice against rotavirus.

Virology 2011 Feb 21;410(1):107-18. Epub 2010 Nov 21.

Department of Microbiology and Ecology, School of Medicine, University of Valencia, Avda. Blasco Ibáñez, 17, 46010 Valencia, Spain.

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February 2011

Vectored vaccines to protect against PRRSV.

Virus Res 2010 Dec 25;154(1-2):150-60. Epub 2010 Jun 25.

Centro Nacional de Biotecnología, CSIC, Department of Molecular and Cell Biology, Campus Universidad Autónoma de Madrid, Darwin 3, 28049 Madrid, Spain.

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December 2010

Rapid differentiation of vaccine strain and Chinese field strains of transmissible gastroenteritis virus by restriction fragment length polymorphism of the N gene.

Virus Genes 2010 Aug 23;41(1):47-58. Epub 2010 Apr 23.

Division of Swine Infectious Diseases, National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, No. 427 Maduan Street, Nangang District, Harbin, 150001, People's Republic of China.

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August 2010

The envelope protein of severe acute respiratory syndrome coronavirus interacts with the non-structural protein 3 and is ubiquitinated.

Virology 2010 Jul 20;402(2):281-91. Epub 2010 Apr 20.

Centro Nacional de Biotecnología (CNB), CSIC, Darwin 3, Campus Universidad Autónoma de Madrid, 28049 Madrid, Spain.

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July 2010

Molecular characterization of a Chinese vaccine strain of transmissible gastroenteritis virus: mutations that may contribute to attenuation.

Virus Genes 2010 Jun 13;40(3):403-9. Epub 2010 Mar 13.

Division of Swine Infectious Diseases, National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute of the Chinese Academy of Agricultural Sciences, Nangang District, Harbin 150001, People's Republic of China.

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June 2010

Immunization with an attenuated severe acute respiratory syndrome coronavirus deleted in E protein protects against lethal respiratory disease.

Virology 2010 Mar 27;399(1):120-128. Epub 2010 Jan 27.

Interdisciplinary Program in Immunology, University of Iowa, Iowa City, IA 52242; Department of Microbiology, University of Iowa, Iowa City, IA 52242. Electronic address:

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March 2010

Coronavirus nucleocapsid protein facilitates template switching and is required for efficient transcription.

J Virol 2010 Feb 2;84(4):2169-75. Epub 2009 Dec 2.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología, CSIC, Darwin, 3, Ciudad Universitaria de Cantoblanco, 28049 Madrid, Spain.

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February 2010

Host cell proteins interacting with the 3' end of TGEV coronavirus genome influence virus replication.

Virology 2009 Sep 5;391(2):304-14. Epub 2009 Jul 5.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología, CSIC, C/Darwin 3, Cantoblanco, 28049 Madrid, Spain.

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September 2009

Comparison of vesicular stomatitis virus pseudotyped with the S proteins from a porcine and a human coronavirus.

J Gen Virol 2009 Jul 4;90(Pt 7):1724-1729. Epub 2009 Mar 4.

Institute of Virology, University of Veterinary Medicine Hannover, Hannover, Germany.

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July 2009

Severe acute respiratory syndrome coronavirus protein 6 is required for optimal replication.

J Virol 2009 Mar 17;83(5):2368-73. Epub 2008 Dec 17.

Department of Microbiology, University of Iowa, Iowa City, Iowa 52242, USA.

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March 2009

Engineering infectious cDNAs of coronavirus as bacterial artificial chromosomes.

Methods Mol Biol 2008 ;454:275-91

Centro Nacional de Biotecnología, CSIC, Department of Molecular and Cell Biology, Cantoblanco, Madrid, Spain.

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March 2009

Recombinant canine coronaviruses related to transmissible gastroenteritis virus of Swine are circulating in dogs.

J Virol 2009 Feb 26;83(3):1532-7. Epub 2008 Nov 26.

Department of Public Health and Animal Sciences, Faculty of Veterinary Medicine, Valenzano (Bari), Italy.

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February 2009

Genome-wide analysis of protein-protein interactions and involvement of viral proteins in SARS-CoV replication.

PLoS One 2008 Oct 1;3(10):e3299. Epub 2008 Oct 1.

State Key Laboratory of Virology and Modern Virology Research Centre, College of Life Sciences, Wuhan University, Wuhan, People's Republic of China.

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October 2008

Role of RNA chaperones in virus replication.

Virus Res 2009 Feb 8;139(2):253-66. Epub 2008 Aug 8.

Centro Nacional de Biotecnología, CSIC, Department of Molecular and Cell Biology, Campus Universitario de Cantoblanco, Darwin 3, 28049 Madrid, Spain.

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February 2009

Pathogenicity of severe acute respiratory coronavirus deletion mutants in hACE-2 transgenic mice.

Virology 2008 Jul 2;376(2):379-89. Epub 2008 May 2.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología (CSIC), Campus Universidad Autónoma, Darwin 3, Cantoblanco, 28049 Madrid, Spain.

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July 2008

Identification of a coronavirus transcription enhancer.

J Virol 2008 Apr 13;82(8):3882-93. Epub 2008 Feb 13.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología, CSIC, C/Darwin 3, Cantoblanco, 28049 Madrid, Spain.

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April 2008

Absence of E protein arrests transmissible gastroenteritis coronavirus maturation in the secretory pathway.

Virology 2007 Nov 10;368(2):296-308. Epub 2007 Aug 10.

Centro Nacional de Biotecnología, CSIC, Department of Molecular and Cell Biology, Campus Universidad Autónoma, Darwin 3, Cantoblanco, 28049 Madrid, Spain.

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November 2007

Vaccines to prevent severe acute respiratory syndrome coronavirus-induced disease.

Virus Res 2008 Apr 9;133(1):45-62. Epub 2007 Apr 9.

Centro Nacional de Biotecnología (CNB), CSIC, Campus Universidad Autónoma, Cantoblanco, Darwin 3, 28049 Madrid, Spain.

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April 2008

A severe acute respiratory syndrome coronavirus that lacks the E gene is attenuated in vitro and in vivo.

J Virol 2007 Feb 15;81(4):1701-13. Epub 2006 Nov 15.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología, CSIC, Darwin 3, Campus Universidad Autónoma, Cantoblanco, 28049 Madrid, Spain.

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February 2007

Biochemical aspects of coronavirus replication.

Adv Exp Med Biol 2006 ;581:13-24

Centro Nacional de Biotecnología, CSIC, Madrid, Spain.

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December 2006

Coronavirus nucleocapsid protein is an RNA chaperone.

Virology 2007 Jan 18;357(2):215-27. Epub 2006 Sep 18.

Centro Nacional de Biotecnología, CSIC, Department of Molecular and Cell Biology, Campus Universidad Autónoma, Darwin 3, Cantoblanco, 28049 Madrid, Spain.

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January 2007

Construction of a severe acute respiratory syndrome coronavirus infectious cDNA clone and a replicon to study coronavirus RNA synthesis.

J Virol 2006 Nov 23;80(21):10900-6. Epub 2006 Aug 23.

Department of Molecular and Cell Biology, Centro Nacional de Biotecnología, CSIC, Darwin 3, Campus Universidad Autónoma, Cantoblanco, 28049 Madrid, Spain.

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November 2006

Methods for preparation of low abundance glycoproteins from mammalian cell supernatants.

Int J Biol Macromol 2006 Aug 2;39(1-3):151-6. Epub 2006 Jun 2.

Centro Nacional de Biotecnologia, CSIC, Campus Universidad Autonoma, 28049 Madrid, Spain.

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August 2006