Luis B Agellon

Luis B Agellon

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Luis B Agellon

Luis B Agellon

Publications by authors named "Luis B Agellon"

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Avoiding raising the ire of IRE1α.

Cell Calcium 2019 Nov 8;83:102056. Epub 2019 Aug 8.

Department of Biochemistry, University of Alberta, Edmonton, Alberta, T6G 2S7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ceca.2019.102056DOI Listing
November 2019

Tauroursodeoxycholic acid attenuates cyclosporine-induced renal fibrogenesis in the mouse model.

Biochim Biophys Acta Gen Subj 2019 Jul 24;1863(7):1210-1216. Epub 2019 Apr 24.

Department of Biochemistry, University of Alberta, Edmonton, Alberta T6G 2H7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2019.04.016DOI Listing
July 2019

Organellar Calcium Handling in the Cellular Reticular Network.

Cold Spring Harb Perspect Biol 2019 Jul 29. Epub 2019 Jul 29.

Department of Biochemistry, University of Alberta, Edmonton, Alberta T6G 2S7, Canada.

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http://dx.doi.org/10.1101/cshperspect.a038265DOI Listing
July 2019

A longitudinal, epigenome-wide study of DNA methylation in anorexia nervosa: results in actively ill, partially weight-restored, long-term remitted and non-eating-disordered women

J Psychiatry Neurosci 2019 05;44(3):205-213

From the Eating Disorders Program, Douglas University Institute (Steiger, Kahan, Thaler, Fletcher, Israël, St-Hilaire, Rossi); the Research Centre, Douglas University Institute (Steiger, Kahan, Thaler, Fletcher, Joober, Israël, St-Hilaire, Rossi); the Department of Psychiatry, McGill University (Steiger, Booij, Thaler, Joober, Israël, St-Hilaire); the Department of Psychology, Concordia University (Booij); the Sainte-Justine Hospital Research Centre, University of Montreal (Booij); the Department of Epidemiology, Biostatistics, and Occupational Health, McGill University (McGregor); the Department of Decision Sciences, HEC Montreal (Labbe); the Department of Pharmacology and Therapeutics, McGill University (Szyf); the School of Human Nutrition, McGill University (Agellon); and the Centre de recherche du Centre Hospitalier, de l’Université de Montréal (CRCHUM) (Gauvin), Montreal, Que., Canada.

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http://dx.doi.org/10.1503/jpn.170242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488489PMC
May 2019

Endoplasmic reticulum calcium dictates the distribution of intracellular unesterified cholesterol.

Cell Calcium 2018 12 10;76:116-121. Epub 2018 Nov 10.

Department of Biochemistry, University of Alberta, Edmonton, Alberta, T6G 2S7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ceca.2018.11.002DOI Listing
December 2018

Stress Coping Strategies in the Heart: An Integrated View.

Front Cardiovasc Med 2018 21;5:168. Epub 2018 Nov 21.

School of Human Nutrition, McGill University, Ste. Anne de Bellevue, QC, Canada.

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https://www.frontiersin.org/article/10.3389/fcvm.2018.00168/
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http://dx.doi.org/10.3389/fcvm.2018.00168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258784PMC
November 2018

The Endoplasmic Reticulum and the Cellular Reticular Network.

Adv Exp Med Biol 2017 ;981:61-76

Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1007/978-3-319-55858-5_4DOI Listing
August 2018

Importance of Nutrients and Nutrient Metabolism on Human Health.

Yale J Biol Med 2018 06 28;91(2):95-103. Epub 2018 Jun 28.

School of Human Nutrition, McGill University, Ste. Anne de Bellevue, QC, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020734PMC
June 2018

Endoplasmic reticulum in health and disease: the 12th International Calreticulin Workshop, Delphi, Greece.

J Cell Mol Med 2017 Dec 21;21(12):3141-3149. Epub 2017 Nov 21.

School of Human Nutrition, McGill University, Ste. Anne de Bellevue, Quebec, Canada.

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http://dx.doi.org/10.1111/jcmm.13413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706586PMC
December 2017

Fatty acid binding protein (Fabp) 5 interacts with the calnexin cytoplasmic domain at the endoplasmic reticulum.

Biochem Biophys Res Commun 2017 11 11;493(1):202-206. Epub 2017 Sep 11.

School of Human Nutrition, McGill University, Ste. Anne de Bellevue, Quebec, H9X 3V9, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X173180
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http://dx.doi.org/10.1016/j.bbrc.2017.09.046DOI Listing
November 2017

Endoplasmic Reticulum Malfunction in the Nervous System.

Front Neurosci 2017 25;11:220. Epub 2017 Apr 25.

School of Dietetics and Human Nutrition, McGill UniversitySte. Anne de Bellevue, QC, Canada.

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http://dx.doi.org/10.3389/fnins.2017.00220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403925PMC
April 2017

The rise of proteostasis promoters.

IUBMB Life 2016 12 31;68(12):943-954. Epub 2016 Oct 31.

Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1002/iub.1576DOI Listing
December 2016

Efficacy of the porcine species in biomedical research.

Front Genet 2015 16;6:293. Epub 2015 Sep 16.

Department of Animal Science, McGill University, Sainte-Anne-de-Bellevue QC, Canada.

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http://journal.frontiersin.org/Article/10.3389/fgene.2015.00
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http://dx.doi.org/10.3389/fgene.2015.00293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4584988PMC
October 2015

Ca(2+) homeostasis and endoplasmic reticulum (ER) stress: An integrated view of calcium signaling.

Biochem Biophys Res Commun 2015 Apr;460(1):114-21

Department of Biochemistry, University of Alberta, Edmonton, Alberta T6G 2H7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2015.02.004DOI Listing
April 2015

Endoplasmic reticulum stress, genome damage, and cancer.

Front Oncol 2015 3;5:11. Epub 2015 Feb 3.

School of Dietetics and Human Nutrition, McGill University , Montréal, QC , Canada.

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http://dx.doi.org/10.3389/fonc.2015.00011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315039PMC
February 2015

Extract of Irish potatoes (Solanum tuberosum L.) decreases body weight gain and adiposity and improves glucose control in the mouse model of diet-induced obesity.

Mol Nutr Food Res 2014 Nov 16;58(11):2235-8. Epub 2014 Sep 16.

School of Dietetics and Human Nutrition, McGill University, QC, Canada.

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http://dx.doi.org/10.1002/mnfr.201400013DOI Listing
November 2014

Coping with endoplasmic reticulum stress in the cardiovascular system.

Annu Rev Physiol 2013 27;75:49-67. Epub 2012 Sep 27.

Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1146/annurev-physiol-030212-183707DOI Listing
August 2013

Transport and biological activities of bile acids.

Int J Biochem Cell Biol 2013 Jul 17;45(7):1389-98. Epub 2013 Apr 17.

School of Dietetics and Human Nutrition, McGill University, Ste Anne de Bellevue, QC, Canada.

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http://dx.doi.org/10.1016/j.biocel.2013.04.012DOI Listing
July 2013

Visualization of sex-dimorphic changes in the intestinal transcriptome of Fabp2 gene-ablated mice.

J Nutrigenet Nutrigenomics 2012 11;5(1):45-55. Epub 2012 May 11.

School of Dietetics and Human Nutrition, McGill University, Ste. Anne de Bellevue, Que., Canada.

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http://dx.doi.org/10.1159/000337193DOI Listing
October 2012

Sex differences in lipid metabolism and metabolic disease risk.

Biochem Cell Biol 2012 Apr 5;90(2):124-41. Epub 2012 Jan 5.

School of Dietetics and Human Nutrition, Macdonald-Stewart Building, McGill University, Ste. Anne de Bellevue, QC H9X 3V9 Canada.

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http://dx.doi.org/10.1139/o11-067DOI Listing
April 2012

The role of phosphatidylethanolamine methyltransferase in a mouse model of intrahepatic cholestasis.

Biochim Biophys Acta 2011 Apr 1;1811(4):278-83. Epub 2011 Feb 1.

Department of Biochemistry and Group on the Molecular and Cell Biology of Lipids, University of Alberta, Edmonton, Alberta T6G 2S2, Canada.

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http://dx.doi.org/10.1016/j.bbalip.2011.01.006DOI Listing
April 2011

Biology of endoplasmic reticulum stress in the heart.

Circ Res 2010 Nov;107(10):1185-97

Department of Biochemistry, School of Molecular and Systems Medicine, University of Alberta, Edmonton, Alberta, Canada.

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http://circres.ahajournals.org/content/107/10/1185.full.pdf
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http://circres.ahajournals.org/cgi/doi/10.1161/CIRCRESAHA.11
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http://dx.doi.org/10.1161/CIRCRESAHA.110.227033DOI Listing
November 2010

Calnexin deficiency leads to dysmyelination.

J Biol Chem 2010 Jun 16;285(24):18928-38. Epub 2010 Apr 16.

Department of Biochemistry, School of Molecular and Systems Medicine, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M110.107201
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http://dx.doi.org/10.1074/jbc.M110.107201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881815PMC
June 2010

Wild rice ( Zizania latifolia (Griseb) Turcz) improves the serum lipid profile and antioxidant status of rats fed with a high fat/cholesterol diet.

Br J Nutr 2009 Dec;102(12):1723-7

School of Public Health, Southeast University, Nanjing City, Jiangsu, People's Republic of China.

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http://dx.doi.org/10.1017/S0007114509991036DOI Listing
December 2009

Molecular and Cellular Biochemistry. Editorial.

Mol Cell Biochem 2009 Jun;326(1-2)

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http://dx.doi.org/10.1007/s11010-009-0068-7DOI Listing
June 2009

Apolipoprotein B and triacylglycerol secretion in human triacylglycerol hydrolase transgenic mice.

J Lipid Res 2007 Dec 18;48(12):2597-606. Epub 2007 Sep 18.

Department of Pediatrics, Canadian Institutes of Health Research Group on the Molecular and Cell Biology of Lipids, University of Alberta, Edmonton, Alberta, Canada T6G 2S2.

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http://dx.doi.org/10.1194/jlr.M700320-JLR200DOI Listing
December 2007

Loss of intestinal fatty acid binding protein increases the susceptibility of male mice to high fat diet-induced fatty liver.

Biochim Biophys Acta 2007 Oct 22;1771(10):1283-8. Epub 2007 Aug 22.

Canadian Institutes of Health Research Molecular and Cell Biology of Lipids Research Group and Department of Biochemistry, University of Alberta, Edmonton, AB, Canada T6G 2S2.

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http://dx.doi.org/10.1016/j.bbalip.2007.08.004DOI Listing
October 2007

The phosphatidylethanolamine N-methyltransferase pathway is quantitatively not essential for biliary phosphatidylcholine secretion.

J Lipid Res 2007 Sep 26;48(9):2058-64. Epub 2007 Jun 26.

Pediatric Gastroenterology/Research Laboratory Pediatrics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1194/jlr.M700278-JLR200DOI Listing
September 2007

Intestinal bile salt absorption in Atp8b1 deficient mice.

J Hepatol 2007 Jul 7;47(1):114-22. Epub 2007 Mar 7.

AMC Liver Center, Academic Medical Center, Room S1-166, Meibergdreef 69-71, 1105 BK Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jhep.2007.02.011DOI Listing
July 2007

A role for high density lipoproteins in hepatic phosphatidylcholine homeostasis.

Biochim Biophys Acta 2007 Jul 21;1771(7):893-900. Epub 2007 Apr 21.

Department of Biochemistry and Canadian Institutes of Health Research Group on the Molecular and Cell Biology of Lipids, University of Alberta, Edmonton, Alberta, Canada T6G 2S2.

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http://dx.doi.org/10.1016/j.bbalip.2007.04.009DOI Listing
July 2007

Choline redistribution during adaptation to choline deprivation.

J Biol Chem 2007 Apr 5;282(14):10283-9. Epub 2007 Feb 5.

Department of Biochemistry and Canadian Institutes of Health Research Group on the Molecular and Cell Biology of Lipids, University of Alberta, Edmonton, Alberta T6G 2S2, Canada.

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http://dx.doi.org/10.1074/jbc.M611726200DOI Listing
April 2007

The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis.

Cell Metab 2006 May;3(5):321-31

Department of Biochemistry and Canadian Institutes of Health Research Group on the Molecular and Cell Biology of Lipids, University of Alberta, Edmonton, Alberta T6G 2S2 Canada.

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http://dx.doi.org/10.1016/j.cmet.2006.03.007DOI Listing
May 2006

Adaptations to the loss of intestinal fatty acid binding protein in mice.

Mol Cell Biochem 2006 Mar;284(1-2):159-66

Department of Biochemistry, Canadian Institutes of Health Research Group in Molecular and Cell Biology of Lipids, Edmonton, Canada.

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http://dx.doi.org/10.1007/s11010-005-9042-1DOI Listing
March 2006

Activation of CFTR by ASBT-mediated bile salt absorption.

Am J Physiol Gastrointest Liver Physiol 2005 Nov 21;289(5):G870-9. Epub 2005 Jul 21.

Dept. of Biochemistry, Erasmus MC, PO Box 1738, 3000 DR Rotterdam, The Netherlands.

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http://dx.doi.org/10.1152/ajpgi.00226.2005DOI Listing
November 2005

Phosphatidylcholine homeostasis and liver failure.

J Biol Chem 2005 Nov 6;280(45):37798-802. Epub 2005 Sep 6.

Department of Biochemistry, University of Alberta, Edmonton, Canada.

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http://www.jbc.org/content/280/45/37798.full.pdf
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http://www.jbc.org/cgi/doi/10.1074/jbc.M508575200
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http://dx.doi.org/10.1074/jbc.M508575200DOI Listing
November 2005

Localization-independent regulation of homocysteine secretion by phosphatidylethanolamine N-methyltransferase.

J Biol Chem 2005 Jul 31;280(29):27339-44. Epub 2005 May 31.

Department of Biochemistry and Canadian Institutes of Health Research Group on Molecular & Cell Biology of Lipids, University of Alberta, Edmonton, Alberta T6G 2S2, Canada.

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http://dx.doi.org/10.1074/jbc.M504658200DOI Listing
July 2005

The age-related decline in intestinal lipid uptake is associated with a reduced abundance of fatty acid-binding protein.

Lipids 2004 Jul;39(7):603-10

Nutrition and Metabolism Group, Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.

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http://link.springer.com/content/pdf/10.1007/s11745-004-1272
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http://dx.doi.org/10.1007/s11745-004-1272-9DOI Listing
July 2004

ABCA1-dependent lipid efflux to apolipoprotein A-I mediates HDL particle formation and decreases VLDL secretion from murine hepatocytes.

J Lipid Res 2004 Jun 1;45(6):1122-31. Epub 2004 Mar 1.

Departments of Pediatrics, CIHR Group on Molecular and Cell Biology of Lipids, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1194/jlr.M300529-JLR200DOI Listing
June 2004

The inhibition of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) promoter by fibrates in cultured cells is mediated via the liver x receptor alpha and peroxisome proliferator-activated receptor alpha heterodimer.

Nucleic Acids Res 2004 11;32(3):1113-21. Epub 2004 Feb 11.

Canadian Institutes of Health Research Group in Molecular and Cell Biology of Lipids and Department of Biochemistry, University of Alberta, Edmonton, Alberta T6G 2S2, Canada.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkh260DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC373396PMC
May 2004

An isocaloric PUFA diet enhances lipid uptake and weight gain in aging rats.

Lipids 2004 Apr;39(4):343-54

Nutrition and Metabolism Group, Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1007/s11745-004-1238-yDOI Listing
April 2004

Regulation of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) by thyroid hormone in transgenic mice.

Endocrinology 2004 Feb 30;145(2):574-81. Epub 2003 Oct 30.

Canadian Institutes of Health Research Group in Molecular and Cell Biology of Lipids, Heritage Medical Research Centre, University of Alberta, Edmonton, Alberta, Canada T6G 2S2.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
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http://dx.doi.org/10.1210/en.2003-0993DOI Listing
February 2004

Inhibition of apolipoprotein B secretion by taurocholate is controlled by the N-terminal end of the protein in rat hepatoma McArdle-RH7777 cells.

Biochim Biophys Acta 2003 Dec;1635(2-3):93-103

Department of Pediatrics, Groningen University Institute for Drug Exploration, Pediatric Gastroenterology, Academic Hospital, The Netherlands.

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http://dx.doi.org/10.1016/j.bbalip.2003.10.009DOI Listing
December 2003

Regulation of triacylglycerol hydrolase expression by dietary fatty acids and peroxisomal proliferator-activated receptors.

Biochim Biophys Acta 2003 Nov;1635(1):20-8

Department of Biochemistry, University of Alberta, 328 Heritage Medical Research Centre, Edmonton, Alberta T6G 2S2, Canada.

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http://dx.doi.org/10.1016/j.bbalip.2003.09.007DOI Listing
November 2003

Enterohepatic circulation of bile salts in farnesoid X receptor-deficient mice: efficient intestinal bile salt absorption in the absence of ileal bile acid-binding protein.

J Biol Chem 2003 Oct 12;278(43):41930-7. Epub 2003 Aug 12.

Groningen University Institute for Drug Exploration, Center for Liver, Digestive, and Metabolic Diseases, University Hospital Groningen, CMC IV, Rm. Y2.163, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M306309200DOI Listing
October 2003

Molecular dissection of the S-adenosylmethionine-binding site of phosphatidylethanolamine N-methyltransferase.

J Biol Chem 2003 Sep 3;278(37):35826-36. Epub 2003 Jul 3.

Department of Biochemistry, and Canadian Institutes of Health Research Group on Molecular & Cell Biology of Lipids, University of Alberta, Edmonton, Alberta T6G 2S2, Canada.

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http://dx.doi.org/10.1074/jbc.M306308200DOI Listing
September 2003

Administration of tyrosyl radical-oxidized HDL inhibits the development of atherosclerosis in apolipoprotein E-deficient mice.

Arterioscler Thromb Vasc Biol 2003 Sep 10;23(9):1583-8. Epub 2003 Jul 10.

CIHR Group on Molecular and Cell Biology of Lipids and Departments of Medicine, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1161/01.ATV.0000085840.67498.00DOI Listing
September 2003

The relative ligand binding preference of the murine ileal lipid binding protein.

Protein Expr Purif 2003 Mar;28(1):25-33

Department of Biochemistry, 328 Heritage Medical Research Centre, University of Alberta, Edmonton, Alberta, Canada T6G 2S2.

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March 2003

Dietary rhubarb (Rheum rhaponticum) stalk fibre does not lower plasma cholesterol levels in diabetic rats.

Br J Nutr 2003 Feb;89(2):201-6

Department of Biochemistry, University of Alberta, Edmonton, Alberta, Canada T6G 2S2.

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http://dx.doi.org/10.1079/BJN2002768DOI Listing
February 2003

Membrane topography of human phosphatidylethanolamine N-methyltransferase.

J Biol Chem 2003 Jan 12;278(5):2956-62. Epub 2002 Nov 12.

Department of Biochemistry and Canadian Institutes of Health Research Group on Molecular and Cell Biology of Lipids, University of Alberta, Edmonton, Alberta T6G 2S2, Canada.

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http://dx.doi.org/10.1074/jbc.M210904200DOI Listing
January 2003

Cardiac-specific expression of calcineurin reverses embryonic lethality in calreticulin-deficient mouse.

J Biol Chem 2002 Dec 10;277(52):50776-9. Epub 2002 Oct 10.

Canadian Institutes of Health Research Membrane Protein Research Group, Canadian Institutes of Health Research Molecular and Cell Biology of Lipids Research Group, Department of Biochemistry, University of Alberta, Edmonton, Alberta T6G 2H7, Canada.

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http://dx.doi.org/10.1074/jbc.M209900200DOI Listing
December 2002

Intracellular lipid binding proteins of the small intestine.

Mol Cell Biochem 2002 Oct;239(1-2):79-82

Canadian Institutes of Health Research Group in Molecular and Cell Biology of Lipids, Department of Biochemistry, University of Alberta, Edmonton, Canada.

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October 2002

The atypical interaction of peroxisome proliferator-activated receptor alpha with liver X receptor alpha antagonizes the stimulatory effect of their respective ligands on the murine cholesterol 7alpha-hydroxylase gene promoter.

Biochim Biophys Acta 2002 Jul;1583(2):229-36

Canadian Institutes of Health Research Group in Molecular and Cell Biology of Lipids and Department of Biochemistry, 328 Heritage Medical Research Centre, University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1016/s1388-1981(02)00217-2DOI Listing
July 2002

Dietary cholesterol fails to stimulate the human cholesterol 7alpha-hydroxylase gene (CYP7A1) in transgenic mice.

J Biol Chem 2002 Jun 19;277(23):20131-4. Epub 2002 Apr 19.

Department of Biochemistry and Canadian Institutes of Health Research Group in Molecular and Cell Biology of Lipids, University of Alberta, Edmonton, Alberta T6G 2S2, Canada.

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http://www.jbc.org/lookup/doi/10.1074/jbc.C200105200
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http://dx.doi.org/10.1074/jbc.C200105200DOI Listing
June 2002

A distinct thyroid hormone response element mediates repression of the human cholesterol 7alpha-hydroxylase (CYP7A1) gene promoter.

Mol Endocrinol 2002 Jan;16(1):14-23

Canadian Institutes of Health Research Group in Molecular and Cell Biology of Lipids, and Department of Biochemistry, University of Alberta, Edmonton, Alberta, T6G 2S2, Canada.

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http://dx.doi.org/10.1210/mend.16.1.0751DOI Listing
January 2002