Luigi Ferrucci

Luigi Ferrucci

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Luigi Ferrucci

Publications by authors named "Luigi Ferrucci"

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Semi-automated 3D segmentation of human skeletal muscle using Focused Ion Beam-Scanning Electron Microscopic images.

J Struct Biol 2019 Jul 23;207(1):1-11. Epub 2019 Mar 23.

University of British Columbia, Vancouver, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jsb.2019.03.008DOI Listing
July 2019

Association Between Adiposity and Perceived Physical Fatigability in Mid- to Late Life.

Obesity (Silver Spring) 2019 Jul 25;27(7):1177-1183. Epub 2019 May 25.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/oby.22500
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http://dx.doi.org/10.1002/oby.22500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591054PMC
July 2019

Association of Midlife Hearing Impairment With Late-Life Temporal Lobe Volume Loss.

JAMA Otolaryngol Head Neck Surg 2019 Jul 3. Epub 2019 Jul 3.

Laboratory of Behavioral Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.

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http://dx.doi.org/10.1001/jamaoto.2019.1610DOI Listing
July 2019

Changes in knee extension peak torque and body composition and their relationship with change in gait speed.

J Cachexia Sarcopenia Muscle 2019 Jul 4. Epub 2019 Jul 4.

Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, USA.

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http://dx.doi.org/10.1002/jcsm.12458DOI Listing
July 2019

Interaction between Vitamin D and Interleukin 6 on Slow Gait Speed: 6-year Follow-up Data of Older Adults from InCHIANTI.

J Gerontol A Biol Sci Med Sci 2019 Jul 6. Epub 2019 Jul 6.

Center on Aging, University of Connecticut Health Center, CT, USA.

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http://dx.doi.org/10.1093/gerona/glz165DOI Listing
July 2019

The transcript expression levels of HNRNPM, HNRNPA0 and AKAP17A splicing factors may be predictively associated with ageing phenotypes in human peripheral blood.

Biogerontology 2019 Jul 10. Epub 2019 Jul 10.

Institute of Biomedical and Clinical Sciences, University of Exeter College of Medicine and Health, RILD Building, RD&E NHSFT Campus, Barrack Rd, Exeter, EX2 5DW, UK.

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http://dx.doi.org/10.1007/s10522-019-09819-0DOI Listing
July 2019

The role of epigenetic aging in education and racial/ethnic mortality disparities among older U.S. Women.

Psychoneuroendocrinology 2019 Jun 6;104:18-24. Epub 2019 Feb 6.

Department of Pathology, Yale School of Medicine, New Haven, CT 06511, USA; Department of Epidemiology, Yale School of Public Health, New Haven, CT 06511, USA. Electronic address:

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http://dx.doi.org/10.1016/j.psyneuen.2019.01.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555423PMC
June 2019

Tetra-linoleoyl cardiolipin depletion plays a major role in the pathogenesis of sarcopenia.

Med Hypotheses 2019 Jun 17;127:142-149. Epub 2019 Apr 17.

National Institute on Aging, National Institutes of Health, Baltimore, MD, United States.

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http://dx.doi.org/10.1016/j.mehy.2019.04.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521864PMC
June 2019

Lap Time Variability From a 400-m Walk Is Associated With Future Mild Cognitive Impairment and Alzheimer's Disease.

J Am Med Dir Assoc 2019 Jun 18. Epub 2019 Jun 18.

Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, MD. Electronic address:

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http://dx.doi.org/10.1016/j.jamda.2019.04.019DOI Listing
June 2019

Sex differences in brain aging and predictors of neurodegeneration in cognitively healthy older adults.

Neurobiol Aging 2019 Jun 5;81:146-156. Epub 2019 Jun 5.

Laboratory of Behavioral Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.05.020DOI Listing
June 2019

Neuroimaging correlates of lateral postural control in older ambulatory adults.

Aging Clin Exp Res 2019 May 28;31(5):611-619. Epub 2018 Aug 28.

Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1007/s40520-018-1028-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6573008PMC
May 2019

Obesity and Longer Term Risks of Dementia in 65-74 Year Olds.

Age Ageing 2019 May;48(3):367-373

Epidemiology and Public Health, Institute of Biomedical and Clinical Science, University of Exeter Medical School, Barrack Road, Exeter, UK.

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http://dx.doi.org/10.1093/ageing/afz002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6512743PMC
May 2019

Assessment of NADmetabolism in human cell cultures, erythrocytes, cerebrospinal fluid and primate skeletal muscle.

Anal Biochem 2019 May 27;572:1-8. Epub 2019 Feb 27.

Biomedical Research Center, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ab.2019.02.019DOI Listing
May 2019

Diffusion-weighted MRI with intravoxel incoherent motion modeling for assessment of muscle perfusion in the thigh during post-exercise hyperemia in younger and older adults.

NMR Biomed 2019 05 12;32(5):e4072. Epub 2019 Mar 12.

Laboratory of Clinical Investigation, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/nbm.4072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530599PMC
May 2019

An emergent integrated aging process conserved across primates.

J Gerontol A Biol Sci Med Sci 2019 May 2. Epub 2019 May 2.

Groupe de recherche PRIMUS, Department of Family Medicine, University of Sherbrooke, Sherbrooke, QC, Canada.

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https://academic.oup.com/biomedgerontology/advance-article/d
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http://dx.doi.org/10.1093/gerona/glz110DOI Listing
May 2019

Moderate-to-Vigorous Physical Activity Is Associated With Higher Muscle Oxidative Capacity in Older Adults.

J Am Geriatr Soc 2019 May 22. Epub 2019 May 22.

Translational Gerontology Branch, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.

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http://dx.doi.org/10.1111/jgs.15991DOI Listing
May 2019

Measuring successful aging: an exploratory factor analysis of the InCHIANTI Study into different health domains.

Aging (Albany NY) 2019 May;11(10):3023-3040

Department of Respiratory Medicine, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre, Maastricht, the Netherlands.

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http://dx.doi.org/10.18632/aging.101957DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555461PMC
May 2019

Genetic analysis of neurodegenerative diseases in a pathology cohort.

Neurobiol Aging 2019 04 17;76:214.e1-214.e9. Epub 2018 Nov 17.

Neurodegenerative Diseases Research Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391207PMC
April 2019

Epigenetic age is a cell-intrinsic property in transplanted human hematopoietic cells.

Aging Cell 2019 Apr 2;18(2):e12897. Epub 2019 Feb 2.

Division of Hematology/Oncology, Department of Medicine, School of Medicine, Case Western Reserve University, Cleveland, Ohio.

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http://dx.doi.org/10.1111/acel.12897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413751PMC
April 2019

Conservation of physiological dysregulation signatures of aging across primates.

Aging Cell 2019 Apr 11;18(2):e12925. Epub 2019 Feb 11.

Groupe de recherche PRIMUS, Department of Family Medicine, University of Sherbrooke, Sherbrooke, Quebec, Canada.

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http://dx.doi.org/10.1111/acel.12925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413749PMC
April 2019

The Role of Muscle Perfusion in the Age-Associated Decline of Mitochondrial Function in Healthy Individuals.

Front Physiol 2019 12;10:427. Epub 2019 Apr 12.

Translational Gerontology Branch, Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD, United States.

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http://dx.doi.org/10.3389/fphys.2019.00427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473080PMC
April 2019

Vascular burden and APOE ε4 are associated with white matter microstructural decline in cognitively normal older adults.

Neuroimage 2019 03 15;188:572-583. Epub 2018 Dec 15.

Laboratory of Behavioral Neuroscience, National Institute on Aging, Baltimore, MD 21224, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2018.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601608PMC
March 2019

Predictors of neurodegeneration differ between cognitively normal and subsequently impaired older adults.

Neurobiol Aging 2019 03 2;75:178-186. Epub 2018 Nov 2.

Laboratory of Behavioral Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01974580183038
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http://dx.doi.org/10.1016/j.neurobiolaging.2018.10.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394867PMC
March 2019

Vitamin D levels and risk of delirium: A mendelian randomization study in the UK Biobank.

Neurology 2019 Mar 15;92(12):e1387-e1394. Epub 2019 Feb 15.

From the Epidemiology and Public Health Group (K.B., L.J., L.C.P., J.D., D.M.), University of Exeter Medical School, Royal Devon & Exeter Hospital, Exeter, UK; UConn Center on Aging (G.A.K., R.H.F., D.M.), University of Connecticut, Farmington, CT; and National Institute on Aging (L.F.), Baltimore, MD.

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http://dx.doi.org/10.1212/WNL.0000000000007136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511096PMC
March 2019

Sex differences in the association between amyloid and longitudinal brain volume change in cognitively normal older adults.

Neuroimage Clin 2019 11;22:101769. Epub 2019 Mar 11.

Laboratory of Behavioral Neuroscience, National Institutes of Health, National Institute on Aging, Baltimore, MD, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2019.101769DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6444285PMC
March 2019

Red cell distribution width and common disease onsets in 240,477 healthy volunteers followed for up to 9 years.

PLoS One 2018 13;13(9):e0203504. Epub 2018 Sep 13.

Epidemiology and Public Health Group, University of Exeter Medical School, Exeter, Devon, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0203504PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136726PMC
February 2019

Predictive Capacity of Frailty Phenotype Toward Patterns of Disability Identified Using Latent Class Analysis.

J Am Med Dir Assoc 2019 Feb 13. Epub 2019 Feb 13.

Geriatric Unit, Campus Bio-Medico University, Rome, Italy.

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http://dx.doi.org/10.1016/j.jamda.2018.12.018DOI Listing
February 2019

Sarcopenia and variation in the Human Leukocyte Antigen complex.

J Gerontol A Biol Sci Med Sci 2019 Feb 17. Epub 2019 Feb 17.

Epidemiology and Public Health Group, University of Exeter Medical School, RILD Building, Barrack Road, Exeter, UK.

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http://dx.doi.org/10.1093/gerona/glz042DOI Listing
February 2019

Association between PUFA intake and serum concentration and mortality in older adults: A cohort study.

Clin Nutr 2019 Feb 23. Epub 2019 Feb 23.

Area di Geriatria, Policlinico Universitario Campus Bio-Medico di Roma, Rome, 00128, Italy.

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http://dx.doi.org/10.1016/j.clnu.2019.02.030DOI Listing
February 2019

Of aging mice and men: gait speed decline is a translatable trait, with species-specific underlying properties.

J Gerontol A Biol Sci Med Sci 2019 Jan 14. Epub 2019 Jan 14.

Translational Gerontology Branch, National Institute on Aging, Intramural Research Program, National Institute of Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1093/gerona/glz015DOI Listing
January 2019

DNA methylation GrimAge strongly predicts lifespan and healthspan.

Aging (Albany NY) 2019 Jan;11(2):303-327

Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA 90095, USA.

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http://www.aging-us.com/article/101684/text
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http://dx.doi.org/10.18632/aging.101684DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366976PMC
January 2019

Physical activity fragmentation as a potential phenotype of accelerated aging.

Oncotarget 2019 Jan 25;10(8):807-809. Epub 2019 Jan 25.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA; Center on Aging and Health, Johns Hopkins University, Baltimore, Maryland, USA.

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http://dx.doi.org/10.18632/oncotarget.26631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368227PMC
January 2019

Contrasting characteristics of daily physical activity in older adults by cancer history.

Cancer 2018 Dec 1;124(24):4692-4699. Epub 2018 Oct 1.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

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http://dx.doi.org/10.1002/cncr.31745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294692PMC
December 2018

Anticholinergic Drug Induced Cognitive and Physical Impairment: Results from the InCHIANTI Study.

J Gerontol A Biol Sci Med Sci 2018 Dec 26. Epub 2018 Dec 26.

Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA.

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http://dx.doi.org/10.1093/gerona/gly289DOI Listing
December 2018

A new aging measure captures morbidity and mortality risk across diverse subpopulations from NHANES IV: A cohort study.

PLoS Med 2018 12 31;15(12):e1002718. Epub 2018 Dec 31.

Department of Pathology, Yale School of Medicine, New Haven, Connecticut, United States of America.

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http://dx.doi.org/10.1371/journal.pmed.1002718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312200PMC
December 2018

Pittsburgh Fatigability Scale: One-Page Predictor of Mobility Decline in Mobility-Intact Older Adults.

J Am Geriatr Soc 2018 Nov 13;66(11):2092-2096. Epub 2018 Oct 13.

Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://doi.wiley.com/10.1111/jgs.15531
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http://dx.doi.org/10.1111/jgs.15531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322394PMC
November 2018

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.

Authors:
Symen Ligthart Ahmad Vaez Urmo Võsa Maria G Stathopoulou Paul S de Vries Bram P Prins Peter J Van der Most Toshiko Tanaka Elnaz Naderi Lynda M Rose Ying Wu Robert Karlsson Maja Barbalic Honghuang Lin René Pool Gu Zhu Aurélien Macé Carlo Sidore Stella Trompet Massimo Mangino Maria Sabater-Lleal John P Kemp Ali Abbasi Tim Kacprowski Niek Verweij Albert V Smith Tao Huang Carola Marzi Mary F Feitosa Kurt K Lohman Marcus E Kleber Yuri Milaneschi Christian Mueller Mahmudul Huq Efthymia Vlachopoulou Leo-Pekka Lyytikäinen Christopher Oldmeadow Joris Deelen Markus Perola Jing Hua Zhao Bjarke Feenstra Marzyeh Amini Jari Lahti Katharina E Schraut Myriam Fornage Bhoom Suktitipat Wei-Min Chen Xiaohui Li Teresa Nutile Giovanni Malerba Jian'an Luan Tom Bak Nicholas Schork Fabiola Del Greco M Elisabeth Thiering Anubha Mahajan Riccardo E Marioni Evelin Mihailov Joel Eriksson Ayse Bilge Ozel Weihua Zhang Maria Nethander Yu-Ching Cheng Stella Aslibekyan Wei Ang Ilaria Gandin Loïc Yengo Laura Portas Charles Kooperberg Edith Hofer Kumar B Rajan Claudia Schurmann Wouter den Hollander Tarunveer S Ahluwalia Jing Zhao Harmen H M Draisma Ian Ford Nicholas Timpson Alexander Teumer Hongyan Huang Simone Wahl YongMei Liu Jie Huang Hae-Won Uh Frank Geller Peter K Joshi Lisa R Yanek Elisabetta Trabetti Benjamin Lehne Diego Vozzi Marie Verbanck Ginevra Biino Yasaman Saba Ingrid Meulenbelt Jeff R O'Connell Markku Laakso Franco Giulianini Patrik K E Magnusson Christie M Ballantyne Jouke Jan Hottenga Grant W Montgomery Fernando Rivadineira Rico Rueedi Maristella Steri Karl-Heinz Herzig David J Stott Cristina Menni Mattias Frånberg Beate St Pourcain Stephan B Felix Tune H Pers Stephan J L Bakker Peter Kraft Annette Peters Dhananjay Vaidya Graciela Delgado Johannes H Smit Vera Großmann Juha Sinisalo Ilkka Seppälä Stephen R Williams Elizabeth G Holliday Matthijs Moed Claudia Langenberg Katri Räikkönen Jingzhong Ding Harry Campbell Michele M Sale Yii-Der I Chen Alan L James Daniela Ruggiero Nicole Soranzo Catharina A Hartman Erin N Smith Gerald S Berenson Christian Fuchsberger Dena Hernandez Carla M T Tiesler Vilmantas Giedraitis David Liewald Krista Fischer Dan Mellström Anders Larsson Yunmei Wang William R Scott Matthias Lorentzon John Beilby Kathleen A Ryan Craig E Pennell Dragana Vuckovic Beverly Balkau Maria Pina Concas Reinhold Schmidt Carlos F Mendes de Leon Erwin P Bottinger Margreet Kloppenburg Lavinia Paternoster Michael Boehnke A W Musk Gonneke Willemsen David M Evans Pamela A F Madden Mika Kähönen Zoltán Kutalik Magdalena Zoledziewska Ville Karhunen Stephen B Kritchevsky Naveed Sattar Genevieve Lachance Robert Clarke Tamara B Harris Olli T Raitakari John R Attia Diana van Heemst Eero Kajantie Rossella Sorice Giovanni Gambaro Robert A Scott Andrew A Hicks Luigi Ferrucci Marie Standl Cecilia M Lindgren John M Starr Magnus Karlsson Lars Lind Jun Z Li John C Chambers Trevor A Mori Eco J C N de Geus Andrew C Heath Nicholas G Martin Juha Auvinen Brendan M Buckley Anton J M de Craen Melanie Waldenberger Konstantin Strauch Thomas Meitinger Rodney J Scott Mark McEvoy Marian Beekman Cristina Bombieri Paul M Ridker Karen L Mohlke Nancy L Pedersen Alanna C Morrison Dorret I Boomsma John B Whitfield David P Strachan Albert Hofman Peter Vollenweider Francesco Cucca Marjo-Riitta Jarvelin J Wouter Jukema Tim D Spector Anders Hamsten Tanja Zeller André G Uitterlinden Matthias Nauck Vilmundur Gudnason Lu Qi Harald Grallert Ingrid B Borecki Jerome I Rotter Winfried März Philipp S Wild Marja-Liisa Lokki Michael Boyle Veikko Salomaa Mads Melbye Johan G Eriksson James F Wilson Brenda W J H Penninx Diane M Becker Bradford B Worrall Greg Gibson Ronald M Krauss Marina Ciullo Gianluigi Zaza Nicholas J Wareham Albertine J Oldehinkel Lyle J Palmer Sarah S Murray Peter P Pramstaller Stefania Bandinelli Joachim Heinrich Erik Ingelsson Ian J Deary Reedik Mägi Liesbeth Vandenput Pim van der Harst Karl C Desch Jaspal S Kooner Claes Ohlsson Caroline Hayward Terho Lehtimäki Alan R Shuldiner Donna K Arnett Lawrence J Beilin Antonietta Robino Philippe Froguel Mario Pirastu Tine Jess Wolfgang Koenig Ruth J F Loos Denis A Evans Helena Schmidt George Davey Smith P Eline Slagboom Gudny Eiriksdottir Andrew P Morris Bruce M Psaty Russell P Tracy Ilja M Nolte Eric Boerwinkle Sophie Visvikis-Siest Alex P Reiner Myron Gross Joshua C Bis Lude Franke Oscar H Franco Emelia J Benjamin Daniel I Chasman Josée Dupuis Harold Snieder Abbas Dehghan Behrooz Z Alizadeh

Am J Hum Genet 2018 11;103(5):691-706

Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297183032
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http://dx.doi.org/10.1016/j.ajhg.2018.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218410PMC
November 2018

Temporal Sequence of Hearing Impairment and Cognition in the Baltimore Longitudinal Study of Aging.

J Gerontol A Biol Sci Med Sci 2018 Nov 30. Epub 2018 Nov 30.

Laboratory of Behavioral Neuroscience, National Institute on Aging, National Institutes of Health, Baltimore, MD.

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https://academic.oup.com/biomedgerontology/advance-article/d
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http://dx.doi.org/10.1093/gerona/gly268DOI Listing
November 2018

Plasma proteomic signature of age in healthy humans.

Aging Cell 2018 Oct 11;17(5):e12799. Epub 2018 Jul 11.

Longitudinal Study Section, Translational Gerontology Branch, NIA, NIH, Baltimore, Maryland.

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http://dx.doi.org/10.1111/acel.12799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156492PMC
October 2018

Plasma metabolomic profiling of a ketamine and placebo crossover trial of major depressive disorder and healthy control subjects.

Psychopharmacology (Berl) 2018 Oct 16;235(10):3017-3030. Epub 2018 Aug 16.

Experimental Therapeutics and Pathophysiology Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1007/s00213-018-4992-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193489PMC
October 2018

Knee extension rate of velocity development affects walking performance differently in men and women.

Exp Gerontol 2018 10 12;112:63-67. Epub 2018 Sep 12.

Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD 21225, United States of America.

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http://dx.doi.org/10.1016/j.exger.2018.09.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6221187PMC
October 2018

Regular low-calorie sweetener consumption is associated with increased secretion of glucose-dependent insulinotropic polypeptide.

Diabetes Obes Metab 2018 09 9;20(9):2282-2285. Epub 2018 May 9.

Intramural Research Programme, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.

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http://doi.wiley.com/10.1111/dom.13328
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http://dx.doi.org/10.1111/dom.13328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105420PMC
September 2018

Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty.

Nat Rev Cardiol 2018 Sep;15(9):505-522

Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.1038/s41569-018-0064-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146930PMC
September 2018

Time and the Metrics of Aging.

Circ Res 2018 Sep;123(7):740-744

From the Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, MD (L.F., P.-L.K., E.M.S.).

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http://dx.doi.org/10.1161/CIRCRESAHA.118.312816DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205734PMC
September 2018

Age-Related Changes in Glucose Metabolism, Hyperglycemia, and Cardiovascular Risk.

Circ Res 2018 Sep;123(7):886-904

From the Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, MD.

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.118.31280
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http://dx.doi.org/10.1161/CIRCRESAHA.118.312806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205735PMC
September 2018

Extracellular RNA profiles with human age.

Aging Cell 2018 Aug 24;17(4):e12785. Epub 2018 May 24.

Laboratory of Epidemiology and Population Science, National Institute on Aging, National Institutes of Health, Baltimore, Maryland.

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http://dx.doi.org/10.1111/acel.12785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052399PMC
August 2018

Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology consortium.

Authors:
Jordi Merino Hassan S Dashti Sherly X Li Chloé Sarnowski Anne E Justice Misa Graff Constantina Papoutsakis Caren E Smith George V Dedoussis Rozenn N Lemaitre Mary K Wojczynski Satu Männistö Julius S Ngwa Minjung Kho Tarunveer S Ahluwalia Natalia Pervjakova Denise K Houston Claude Bouchard Tao Huang Marju Orho-Melander Alexis C Frazier-Wood Dennis O Mook-Kanamori Louis Pérusse Craig E Pennell Paul S de Vries Trudy Voortman Olivia Li Stavroula Kanoni Lynda M Rose Terho Lehtimäki Jing Hua Zhao Mary F Feitosa Jian'an Luan Nicola M McKeown Jennifer A Smith Torben Hansen Niina Eklund Mike A Nalls Tuomo Rankinen Jinyan Huang Dena G Hernandez Christina-Alexandra Schulz Ani Manichaikul Ruifang Li-Gao Marie-Claude Vohl Carol A Wang Frank J A van Rooij Jean Shin Ioanna P Kalafati Felix Day Paul M Ridker Mika Kähönen David S Siscovick Claudia Langenberg Wei Zhao Arne Astrup Paul Knekt Melissa Garcia D C Rao Qibin Qi Luigi Ferrucci Ulrika Ericson John Blangero Albert Hofman Zdenka Pausova Vera Mikkilä Nick J Wareham Sharon L R Kardia Oluf Pedersen Antti Jula Joanne E Curran M Carola Zillikens Jorma S Viikari Nita G Forouhi José M Ordovás John C Lieske Harri Rissanen André G Uitterlinden Olli T Raitakari Jessica C Kiefte-de Jong Josée Dupuis Jerome I Rotter Kari E North Robert A Scott Michael A Province Markus Perola L Adrienne Cupples Stephen T Turner Thorkild I A Sørensen Veikko Salomaa Yongmei Liu Yun J Sung Lu Qi Stefania Bandinelli Stephen S Rich Renée de Mutsert Angelo Tremblay Wendy H Oddy Oscar H Franco Tomas Paus Jose C Florez Panos Deloukas Leo-Pekka Lyytikäinen Daniel I Chasman Audrey Y Chu Toshiko Tanaka

Mol Psychiatry 2018 Jul 9. Epub 2018 Jul 9.

Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA.

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http://dx.doi.org/10.1038/s41380-018-0079-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326896PMC
July 2018

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity.

Authors:
Jessica van Setten Jennifer A Brody Yalda Jamshidi Brenton R Swenson Anne M Butler Harry Campbell Fabiola M Del Greco Daniel S Evans Quince Gibson Daniel F Gudbjartsson Kathleen F Kerr Bouwe P Krijthe Leo-Pekka Lyytikäinen Christian Müller Martina Müller-Nurasyid Ilja M Nolte Sandosh Padmanabhan Marylyn D Ritchie Antonietta Robino Albert V Smith Maristella Steri Toshiko Tanaka Alexander Teumer Stella Trompet Sheila Ulivi Niek Verweij Xiaoyan Yin David O Arnar Folkert W Asselbergs Joel S Bader John Barnard Josh Bis Stefan Blankenberg Eric Boerwinkle Yuki Bradford Brendan M Buckley Mina K Chung Dana Crawford Marcel den Hoed Josh C Denny Anna F Dominiczak Georg B Ehret Mark Eijgelsheim Patrick T Ellinor Stephan B Felix Oscar H Franco Lude Franke Tamara B Harris Hilma Holm Gandin Ilaria Annamaria Iorio Mika Kähönen Ivana Kolcic Jan A Kors Edward G Lakatta Lenore J Launer Honghuang Lin Henry J Lin Ruth J F Loos Steven A Lubitz Peter W Macfarlane Jared W Magnani Irene Mateo Leach Thomas Meitinger Braxton D Mitchell Thomas Munzel George J Papanicolaou Annette Peters Arne Pfeufer Peter P Pramstaller Olli T Raitakari Jerome I Rotter Igor Rudan Nilesh J Samani David Schlessinger Claudia T Silva Aldana Moritz F Sinner Jonathan D Smith Harold Snieder Elsayed Z Soliman Timothy D Spector David J Stott Konstantin Strauch Kirill V Tarasov Unnur Thorsteinsdottir Andre G Uitterlinden David R Van Wagoner Uwe Völker Henry Völzke Melanie Waldenberger Harm Jan Westra Philipp S Wild Tanja Zeller Alvaro Alonso Christy L Avery Stefania Bandinelli Emelia J Benjamin Francesco Cucca Marcus Dörr Luigi Ferrucci Paolo Gasparini Vilmundur Gudnason Caroline Hayward Susan R Heckbert Andrew A Hicks J Wouter Jukema Stefan Kääb Terho Lehtimäki Yongmei Liu Patricia B Munroe Afshin Parsa Ozren Polasek Bruce M Psaty Dan M Roden Renate B Schnabel Gianfranco Sinagra Kari Stefansson Bruno H Stricker Pim van der Harst Cornelia M van Duijn James F Wilson Sina A Gharib Paul I W de Bakker Aaron Isaacs Dan E Arking Nona Sotoodehnia

Nat Commun 2018 07 25;9(1):2904. Epub 2018 Jul 25.

Departments of Medicine and Epidemiology, Cardiovascular Health Research Unit, Division of Cardiology, University of Washington, Seattle, 98101, WA, USA.

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http://dx.doi.org/10.1038/s41467-018-04766-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060178PMC
July 2018

Searching for a mitochondrial root to the decline in muscle function with ageing.

J Cachexia Sarcopenia Muscle 2018 06 18;9(3):435-440. Epub 2018 May 18.

Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/jcsm.12313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989834PMC
June 2018

Gut dysbiosis: a potential link between increased cancer risk in ageing and inflammaging.

Lancet Oncol 2018 06 1;19(6):e295-e304. Epub 2018 Jun 1.

Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/S1470-2045(18)30095-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047065PMC
June 2018

Rate of muscle contraction is associated with cognition in women, not in men.

J Gerontol A Biol Sci Med Sci 2018 May 8. Epub 2018 May 8.

Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging.

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http://dx.doi.org/10.1093/gerona/gly115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477643PMC
May 2018

Longitudinal Relationship between Interleukin-6 and Perceived Fatigability among well-functioning Adults in mid-to-late Life.

J Gerontol A Biol Sci Med Sci 2018 May 26. Epub 2018 May 26.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1093/gerona/gly120DOI Listing
May 2018

Detecting Risk Of Postural hypotension (DROP): derivation and validation of a prediction score for primary care.

BMJ Open 2018 04 20;8(4):e020740. Epub 2018 Apr 20.

Primary Care Research Group, Institute of Health Research, University of Exeter Medical School, Exeter, UK.

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http://dx.doi.org/10.1136/bmjopen-2017-020740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914723PMC
April 2018

Metabolic Syndrome and Amyloid Accumulation in the Aging Brain.

J Alzheimers Dis 2018 ;65(2):629-639

Intramural Research Program, National Institute on Aging, NIH, Baltimore, MD, USA.

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http://dx.doi.org/10.3233/JAD-180297DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176485PMC
January 2018