Luigi Bouchard

Luigi Bouchard

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Luigi Bouchard

Publications by authors named "Luigi Bouchard"

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Allele length of the DMPK CTG repeat is a predictor of progressive myotonic dystrophy type 1 phenotypes.

Hum Mol Genet 2019 Jul;28(13):2245-2254

Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.

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http://dx.doi.org/10.1093/hmg/ddz055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586140PMC
July 2019

Comparison of Illumina 450K and EPIC arrays in placental DNA methylation.

Epigenetics 2019 Jun 28:1-6. Epub 2019 Jun 28.

b Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke (CHUS) , Sherbrooke , Canada.

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http://dx.doi.org/10.1080/15592294.2019.1634975DOI Listing
June 2019

gene DNA methylation levels are associated with muscular and respiratory profiles in DM1.

Neurol Genet 2019 Jun 23;5(3):e338. Epub 2019 May 23.

Department of Biochemistry (C.L., S.-P.G., L.B.), Université de Sherbrooke, Sherbrooke; ECOGENE-21 Biocluster (C.L., S.-P.G., L.B.), Chicoutimi, Québec, Canada; Groupe de Recherche interdisciplinaire sur les maladies neuromusculaires (C.L., J.M., C.G., L.B.), Saguenay, Canada; Institute of Molecular (G.O., D.G.M.), Cell and Systems Biology, University of Glasgow, United Kingdom; and Centre de Recherche Charles-Le-Moyne-Saguenay-Lac-StJean sur les innovations en santé (J.M., C.G.), Faculté de médecine et des sciences de la santé, Université de Sherbrooke, Canada.

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http://dx.doi.org/10.1212/NXG.0000000000000338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568328PMC
June 2019

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.

Authors:
Nicole M Warrington Robin N Beaumont Momoko Horikoshi Felix R Day Øyvind Helgeland Charles Laurin Jonas Bacelis Shouneng Peng Ke Hao Bjarke Feenstra Andrew R Wood Anubha Mahajan Jessica Tyrrell Neil R Robertson N William Rayner Zhen Qiao Gunn-Helen Moen Marc Vaudel Carmen J Marsit Jia Chen Michael Nodzenski Theresia M Schnurr Mohammad H Zafarmand Jonathan P Bradfield Niels Grarup Marjolein N Kooijman Ruifang Li-Gao Frank Geller Tarunveer S Ahluwalia Lavinia Paternoster Rico Rueedi Ville Huikari Jouke-Jan Hottenga Leo-Pekka Lyytikäinen Alana Cavadino Sarah Metrustry Diana L Cousminer Ying Wu Elisabeth Thiering Carol A Wang Christian T Have Natalia Vilor-Tejedor Peter K Joshi Jodie N Painter Ioanna Ntalla Ronny Myhre Niina Pitkänen Elisabeth M van Leeuwen Raimo Joro Vasiliki Lagou Rebecca C Richmond Ana Espinosa Sheila J Barton Hazel M Inskip John W Holloway Loreto Santa-Marina Xavier Estivill Wei Ang Julie A Marsh Christoph Reichetzeder Letizia Marullo Berthold Hocher Kathryn L Lunetta Joanne M Murabito Caroline L Relton Manolis Kogevinas Leda Chatzi Catherine Allard Luigi Bouchard Marie-France Hivert Ge Zhang Louis J Muglia Jani Heikkinen Camilla S Morgen Antoine H C van Kampen Barbera D C van Schaik Frank D Mentch Claudia Langenberg Jian'an Luan Robert A Scott Jing Hua Zhao Gibran Hemani Susan M Ring Amanda J Bennett Kyle J Gaulton Juan Fernandez-Tajes Natalie R van Zuydam Carolina Medina-Gomez Hugoline G de Haan Frits R Rosendaal Zoltán Kutalik Pedro Marques-Vidal Shikta Das Gonneke Willemsen Hamdi Mbarek Martina Müller-Nurasyid Marie Standl Emil V R Appel Cilius E Fonvig Caecilie Trier Catharina E M van Beijsterveldt Mario Murcia Mariona Bustamante Sílvia Bonas-Guarch David M Hougaard Josep M Mercader Allan Linneberg Katharina E Schraut Penelope A Lind Sarah E Medland Beverley M Shields Bridget A Knight Jin-Fang Chai Kalliope Panoutsopoulou Meike Bartels Friman Sánchez Jakob Stokholm David Torrents Rebecca K Vinding Sara M Willems Mustafa Atalay Bo L Chawes Peter Kovacs Inga Prokopenko Marcus A Tuke Hanieh Yaghootkar Katherine S Ruth Samuel E Jones Po-Ru Loh Anna Murray Michael N Weedon Anke Tönjes Michael Stumvoll Kim F Michaelsen Aino-Maija Eloranta Timo A Lakka Cornelia M van Duijn Wieland Kiess Antje Körner Harri Niinikoski Katja Pahkala Olli T Raitakari Bo Jacobsson Eleftheria Zeggini George V Dedoussis Yik-Ying Teo Seang-Mei Saw Grant W Montgomery Harry Campbell James F Wilson Tanja G M Vrijkotte Martine Vrijheid Eco J C N de Geus M Geoffrey Hayes Haja N Kadarmideen Jens-Christian Holm Lawrence J Beilin Craig E Pennell Joachim Heinrich Linda S Adair Judith B Borja Karen L Mohlke Johan G Eriksson Elisabeth E Widén Andrew T Hattersley Tim D Spector Mika Kähönen Jorma S Viikari Terho Lehtimäki Dorret I Boomsma Sylvain Sebert Peter Vollenweider Thorkild I A Sørensen Hans Bisgaard Klaus Bønnelykke Jeffrey C Murray Mads Melbye Ellen A Nohr Dennis O Mook-Kanamori Fernando Rivadeneira Albert Hofman Janine F Felix Vincent W V Jaddoe Torben Hansen Charlotta Pisinger Allan A Vaag Oluf Pedersen André G Uitterlinden Marjo-Riitta Järvelin Christine Power Elina Hyppönen Denise M Scholtens William L Lowe George Davey Smith Nicholas J Timpson Andrew P Morris Nicholas J Wareham Hakon Hakonarson Struan F A Grant Timothy M Frayling Debbie A Lawlor Pål R Njølstad Stefan Johansson Ken K Ong Mark I McCarthy John R B Perry David M Evans Rachel M Freathy

Nat Genet 2019 05 1;51(5):804-814. Epub 2019 May 1.

Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Royal Devon and Exeter Hospital, Exeter, UK.

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http://dx.doi.org/10.1038/s41588-019-0403-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522365PMC
May 2019

Locus-specific DNA methylation prediction in cord blood and placenta.

Epigenetics 2019 Apr 18;14(4):405-420. Epub 2019 Mar 18.

f Department of Epidemiology , Harvard T.H. Chan School of Public Health , Boston , MA , USA.

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http://dx.doi.org/10.1080/15592294.2019.1588685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557556PMC
April 2019

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight.

Authors:
Leanne K Küpers Claire Monnereau Gemma C Sharp Paul Yousefi Lucas A Salas Akram Ghantous Christian M Page Sarah E Reese Allen J Wilcox Darina Czamara Anne P Starling Alexei Novoloaca Samantha Lent Ritu Roy Cathrine Hoyo Carrie V Breton Catherine Allard Allan C Just Kelly M Bakulski John W Holloway Todd M Everson Cheng-Jian Xu Rae-Chi Huang Diana A van der Plaat Matthias Wielscher Simon Kebede Merid Vilhelmina Ullemar Faisal I Rezwan Jari Lahti Jenny van Dongen Sabine A S Langie Tom G Richardson Maria C Magnus Ellen A Nohr Zongli Xu Liesbeth Duijts Shanshan Zhao Weiming Zhang Michelle Plusquin Dawn L DeMeo Olivia Solomon Joosje H Heimovaara Dereje D Jima Lu Gao Mariona Bustamante Patrice Perron Robert O Wright Irva Hertz-Picciotto Hongmei Zhang Margaret R Karagas Ulrike Gehring Carmen J Marsit Lawrence J Beilin Judith M Vonk Marjo-Riitta Jarvelin Anna Bergström Anne K Örtqvist Susan Ewart Pia M Villa Sophie E Moore Gonneke Willemsen Arnout R L Standaert Siri E Håberg Thorkild I A Sørensen Jack A Taylor Katri Räikkönen Ivana V Yang Katerina Kechris Tim S Nawrot Matt J Silver Yun Yun Gong Lorenzo Richiardi Manolis Kogevinas Augusto A Litonjua Brenda Eskenazi Karen Huen Hamdi Mbarek Rachel L Maguire Terence Dwyer Martine Vrijheid Luigi Bouchard Andrea A Baccarelli Lisa A Croen Wilfried Karmaus Denise Anderson Maaike de Vries Sylvain Sebert Juha Kere Robert Karlsson Syed Hasan Arshad Esa Hämäläinen Michael N Routledge Dorret I Boomsma Andrew P Feinberg Craig J Newschaffer Eva Govarts Matthieu Moisse M Daniele Fallin Erik Melén Andrew M Prentice Eero Kajantie Catarina Almqvist Emily Oken Dana Dabelea H Marike Boezen Phillip E Melton Rosalind J Wright Gerard H Koppelman Letizia Trevisi Marie-France Hivert Jordi Sunyer Monica C Munthe-Kaas Susan K Murphy Eva Corpeleijn Joseph Wiemels Nina Holland Zdenko Herceg Elisabeth B Binder George Davey Smith Vincent W V Jaddoe Rolv T Lie Wenche Nystad Stephanie J London Debbie A Lawlor Caroline L Relton Harold Snieder Janine F Felix

Nat Commun 2019 04 23;10(1):1893. Epub 2019 Apr 23.

The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41467-019-09671-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478731PMC
April 2019

Prenatal determinants of childhood obesity: a review of risk factors .

Can J Physiol Pharmacol 2019 Mar 19;97(3):147-154. Epub 2019 Jan 19.

b Centre de recherche de Centre Hospitalier Universitaire de Sherbrooke (CRCHUS) and Department of Obstetrics and Gynecology, Université de Sherbrooke, Quebec, QC J1H 5N4, Canada.

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http://www.nrcresearchpress.com/doi/10.1139/cjpp-2018-0403
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http://dx.doi.org/10.1139/cjpp-2018-0403DOI Listing
March 2019

Maternal lipid profile differs by gestational diabetes physiologic subtype.

Metabolism 2019 02 20;91:39-42. Epub 2018 Nov 20.

Diabetes Unit, Endocrine Division, Massachusetts General Hospital, Boston, MA, USA; Centre de Recherche du Centre hospitalier universitaire de Sherbrooke (CHUS), Québec, Canada; Department of Population Medicine, Harvard Pilgrim Health Care Institute, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2018.11.008DOI Listing
February 2019

Placental DNA Methylation Adaptation to Maternal Glycemic Response in Pregnancy.

Diabetes 2018 08 11;67(8):1673-1683. Epub 2018 May 11.

Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA

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http://dx.doi.org/10.2337/db18-0123DOI Listing
August 2018

An analytic approach for interpretable predictive models in high-dimensional data in the presence of interactions with exposures.

Genet Epidemiol 2018 04 8;42(3):233-249. Epub 2018 Feb 8.

Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, QC, Canada.

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http://dx.doi.org/10.1002/gepi.22112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175336PMC
April 2018

Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium.

Authors:
Janine F Felix Bonnie R Joubert Andrea A Baccarelli Gemma C Sharp Catarina Almqvist Isabella Annesi-Maesano Hasan Arshad Nour Baïz Marian J Bakermans-Kranenburg Kelly M Bakulski Elisabeth B Binder Luigi Bouchard Carrie V Breton Bert Brunekreef Kelly J Brunst Esteban G Burchard Mariona Bustamante Leda Chatzi Monica Cheng Munthe-Kaas Eva Corpeleijn Darina Czamara Dana Dabelea George Davey Smith Patrick De Boever Liesbeth Duijts Terence Dwyer Celeste Eng Brenda Eskenazi Todd M Everson Fahimeh Falahi M Daniele Fallin Sara Farchi Mariana F Fernandez Lu Gao Tom R Gaunt Akram Ghantous Matthew W Gillman Semira Gonseth Veit Grote Olena Gruzieva Siri E Håberg Zdenko Herceg Marie-France Hivert Nina Holland John W Holloway Cathrine Hoyo Donglei Hu Rae-Chi Huang Karen Huen Marjo-Riitta Järvelin Dereje D Jima Allan C Just Margaret R Karagas Robert Karlsson Wilfried Karmaus Katerina J Kechris Juha Kere Manolis Kogevinas Berthold Koletzko Gerard H Koppelman Leanne K Küpers Christine Ladd-Acosta Jari Lahti Nathalie Lambrechts Sabine A S Langie Rolv T Lie Andrew H Liu Maria C Magnus Per Magnus Rachel L Maguire Carmen J Marsit Wendy McArdle Erik Melén Phillip Melton Susan K Murphy Tim S Nawrot Lorenza Nisticò Ellen A Nohr Björn Nordlund Wenche Nystad Sam S Oh Emily Oken Christian M Page Patrice Perron Göran Pershagen Costanza Pizzi Michelle Plusquin Katri Raikkonen Sarah E Reese Eva Reischl Lorenzo Richiardi Susan Ring Ritu P Roy Peter Rzehak Greet Schoeters David A Schwartz Sylvain Sebert Harold Snieder Thorkild I A Sørensen Anne P Starling Jordi Sunyer Jack A Taylor Henning Tiemeier Vilhelmina Ullemar Marina Vafeiadi Marinus H Van Ijzendoorn Judith M Vonk Annette Vriens Martine Vrijheid Pei Wang Joseph L Wiemels Allen J Wilcox Rosalind J Wright Cheng-Jian Xu Zongli Xu Ivana V Yang Paul Yousefi Hongmei Zhang Weiming Zhang Shanshan Zhao Golareh Agha Caroline L Relton Vincent W V Jaddoe Stephanie J London

Int J Epidemiol 2018 02;47(1):22-23u

National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, USA.

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http://dx.doi.org/10.1093/ije/dyx190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837319PMC
February 2018

Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics.

Hum Mol Genet 2018 02;27(4):742-756

Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK.

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http://dx.doi.org/10.1093/hmg/ddx429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886200PMC
February 2018

PACE4 Undergoes an Oncogenic Alternative Splicing Switch in Cancer.

Cancer Res 2017 12 9;77(24):6863-6879. Epub 2017 Oct 9.

Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Québec, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-1397DOI Listing
December 2017

Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium.

Hum Mol Genet 2017 10;26(20):4067-4085

MRC Integrative Epidemiology Unit.

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http://dx.doi.org/10.1093/hmg/ddx290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656174PMC
October 2017

microRNAs in lipoprotein and lipid metabolism: from biological function to clinical application.

Clin Chem Lab Med 2017 May;55(5):667-686

Département de biochimie, Université de Sherbrooke, Sherbrooke, Québec.

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http://dx.doi.org/10.1515/cclm-2016-0575DOI Listing
May 2017

Genetic determinants of adiponectin regulation revealed by pregnancy.

Obesity (Silver Spring) 2017 05 20;25(5):935-944. Epub 2017 Mar 20.

Department of Medicine, Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

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http://dx.doi.org/10.1002/oby.21805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404994PMC
May 2017

MicroRNAs in Pregnancy and Gestational Diabetes Mellitus: Emerging Role in Maternal Metabolic Regulation.

Curr Diab Rep 2017 05;17(5):35

Department of Biochemistry, Universite de Sherbrooke, Sherbrooke, QC, Canada.

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http://dx.doi.org/10.1007/s11892-017-0856-5DOI Listing
May 2017

Changes in high-density lipoprotein-carried miRNA contribution to the plasmatic pool after consumption of dietary trans fat in healthy men.

Epigenomics 2017 05 4;9(5):669-688. Epub 2017 May 4.

Department of Biochemistry, Université de Sherbrooke, Sherbrooke, Québec, Canada.

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http://dx.doi.org/10.2217/epi-2016-0177DOI Listing
May 2017

Altered DNA Methylation of Long Noncoding RNA H19 in Calcific Aortic Valve Disease Promotes Mineralization by Silencing NOTCH1.

Circulation 2016 Dec 27;134(23):1848-1862. Epub 2016 Oct 27.

From Laboratory of Cardiovascular Pathobiology, Quebec Heart and Lung Institute/Research Center, Department of Surgery (F.H., M.-C.B, N.G., S.A., G.M., R.B., M.J.N., P.M.), Department of Molecular Medicine (J.T.M., S.G.-O., Y.B.), and Department of Medicine (P.P.), Laval University, Quebec, QC, Canada; Department of Biochemistry, Université de Sherbrooke, Sherbrooke, QC, Canada (S.-P.G., L.B.); and ECOGENE-21 and Lipid Clinic, Chicoutimi Hospital, Saguenay, QC, Canada (S.-P.G., L.B.).

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http://circ.ahajournals.org/content/early/2016/10/26/CIRCULA
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http://circ.ahajournals.org/content/circulationaha/134/23/18
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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.023116DOI Listing
December 2016

Validation of a DNA methylation reference panel for the estimation of nucleated cells types in cord blood.

Epigenetics 2016 Nov 26;11(11):773-779. Epub 2016 Sep 26.

a Department of Population Medicine , Harvard Pilgrim Health Care Institute, Harvard Medical School , Boston , MA , USA.

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http://dx.doi.org/10.1080/15592294.2016.1233091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5221601PMC
November 2016

Heterogeneous Contribution of Insulin Sensitivity and Secretion Defects to Gestational Diabetes Mellitus.

Diabetes Care 2016 Jun 13;39(6):1052-5. Epub 2016 May 13.

Diabetes Unit, Massachusetts General Hospital, Boston, MA Harvard Medical School, Boston, MA Université de Sherbrooke, Québec, Canada Centre de Recherché Clinique Étienne-Le Bel of the Centre Hospitalier Universitaire de Sherbrooke, Québec, Canada Department of Population Medicine, Harvard Pilgrim Health Care Institute, Boston, MA

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http://dx.doi.org/10.2337/dc15-2672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4878218PMC
June 2016

Epigenetic and genetic variations at the TNNT1 gene locus are associated with HDL-C levels and coronary artery disease.

Epigenomics 2016 Mar 7;8(3):359-71. Epub 2016 Mar 7.

Department of Biochemistry, Université de Sherbrooke, Sherbrooke, QC J1K 2R1, Canada.

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http://dx.doi.org/10.2217/epi.15.120DOI Listing
March 2016

Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight.

JAMA 2016 Mar;315(11):1129-40

Institute of Biomedical and Clinical Science, University of Exeter Medical School, Royal Devon and Exeter Hospital, Exeter, United Kingdom5Medical Research Council Integrative Epidemiology Unit at the University of Bristol, United Kingdom.

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http://dx.doi.org/10.1001/jama.2016.1975DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4811305PMC
March 2016

funtooNorm: an R package for normalization of DNA methylation data when there are multiple cell or tissue types.

Bioinformatics 2016 Feb 24;32(4):593-5. Epub 2015 Oct 24.

Lady Davis Institute, Jewish General Hospital, Montreal, QC H3T 1E2, Canada, Department of Biochemistry, Université de Sherbrooke, QC J1K 2R1, Canada, Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC H3A 1A2, Canada, Department of Human Genetics, McGill University, Montreal, QC H3A 1B1, Canada and.

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http://dx.doi.org/10.1093/bioinformatics/btv615DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743629PMC
February 2016

Genetics of Glucose regulation in Gestation and Growth (Gen3G): a prospective prebirth cohort of mother-child pairs in Sherbrooke, Canada.

BMJ Open 2016 Feb 3;6(2):e010031. Epub 2016 Feb 3.

Faculty of Medicine and Life Sciences, Department of Medicine, Université de Sherbrooke, Sherbrooke, Quebec, Canada Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada Department of Population Medicine, Harvard Pilgrim Health Care Institute, Harvard Medical School, Boston, Massachusetts, USA Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1136/bmjopen-2015-010031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746442PMC
February 2016

Timing of Excessive Weight Gain During Pregnancy Modulates Newborn Anthropometry.

J Obstet Gynaecol Can 2016 Feb 2;38(2):108-17. Epub 2016 Mar 2.

Department of Medicine, Université de Sherbrooke, Sherbrooke QC; Department of Population Medicine, Harvard Pilgrim Health Care Institute, Boston MA; Massachusetts General Hospital, Boston MA.

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http://dx.doi.org/10.1016/j.jogc.2015.12.014DOI Listing
February 2016

A study in familial hypercholesterolemia suggests reduced methylomic plasticity in men with coronary artery disease.

Epigenomics 2015 ;7(1):17-34

Department of Biochemistry, Université de Sherbrooke, University-Affiliated Chicoutimi Hospital, 305 rue St-Vallier, Saguenay, Québec G7H 5H6, Canada.

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http://dx.doi.org/10.2217/epi.14.64DOI Listing
September 2015

DNA methylation signature of interleukin 1 receptor type II in asthma.

Clin Epigenetics 2015 5;7:80. Epub 2015 Aug 5.

Département des sciences fondamentales, Université du Québec à Chicoutimi, Chicoutimi, QC Canada.

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http://dx.doi.org/10.1186/s13148-015-0114-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526162PMC
August 2015

Glycation of fetal hemoglobin reflects hyperglycemia exposure in utero.

Diabetes Care 2014 Oct 10;37(10):2830-3. Epub 2014 Jul 10.

Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada Endocrine Division, Université de Sherbrooke, Sherbrooke, QC, Canada

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http://dx.doi.org/10.2337/dc14-0549DOI Listing
October 2014

Acetylsalicylic acid, aging and coronary artery disease are associated with ABCA1 DNA methylation in men.

Clin Epigenetics 2014 29;6(1):14. Epub 2014 Jul 29.

Department of Biochemistry, Faculté de médecine et des sciences de la santé, de l'Université de Sherbrooke, 3001 12e Avenue Nord, Sherbrooke, Québec J1H 5 N4, Canada ; ECOGENE-21 and Lipid Clinic, Chicoutimi Hospital, 305 rue St-Vallier, Saguenay, Québec G7H5H6, Canada.

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http://dx.doi.org/10.1186/1868-7083-6-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4120725PMC
August 2014

Epipolymorphisms within lipoprotein genes contribute independently to plasma lipid levels in familial hypercholesterolemia.

Epigenetics 2014 May 6;9(5):718-29. Epub 2014 Feb 6.

Department of Biochemistry; Université de Sherbrooke; Sherbrooke, QC Canada; ECOGENE-21 and Lipid Clinic; Chicoutimi Hospital; Saguenay, QC Canada.

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http://dx.doi.org/10.4161/epi.27981DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063831PMC
May 2014

Cross-tissue comparisons of leptin and adiponectin: DNA methylation profiles.

Adipocyte 2014 Apr 25;3(2):132-40. Epub 2014 Feb 25.

Department of Biochemistry; Université de Sherbrooke; Sherbrooke, QC Canada ; ECOGENE-21 and Clinical Research Center and Lipid Clinic; Chicoutimi Hospital; Saguenay, QC Canada.

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http://dx.doi.org/10.4161/adip.28308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979878PMC
April 2014

Adaptations of placental and cord blood ABCA1 DNA methylation profile to maternal metabolic status.

Epigenetics 2013 Dec 10;8(12):1289-302. Epub 2013 Oct 10.

Department of Biochemistry; Université de Sherbrooke; Sherbrooke, QC Canada; ECOGENE-21 and Lipid Clinic; Chicoutimi Hospital; Saguenay, QC Canada.

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http://dx.doi.org/10.4161/epi.26554DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3933490PMC
December 2013

Epigenetic programming of obesity and diabetes by in utero exposure to gestational diabetes mellitus.

Nutr Rev 2013 Oct;71 Suppl 1:S88-94

Department of Biochemistry, Université de Sherbrooke, Sherbrooke, Quebec, Canada; ECOGENE-21 and Lipid Clinic, Chicoutimi Hospital, Saguenay, Quebec, Canada.

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http://nutritionreviews.oxfordjournals.org/content/nutrition
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http://nutritionreviews.oxfordjournals.org/cgi/doi/10.1111/n
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http://dx.doi.org/10.1111/nure.12057DOI Listing
October 2013

Gestational diabetes mellitus epigenetically affects genes predominantly involved in metabolic diseases.

Epigenetics 2013 Sep 18;8(9):935-43. Epub 2013 Jul 18.

Department of Biochemistry; Université de Sherbrooke; Sherbrooke, QC Canada; ECOGENE-21 Laboratory and Lipid Clinic; Chicoutimi Hospital; Saguenay, QC Canada; These authors contributed equally to this work.

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http://dx.doi.org/10.4161/epi.25578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883770PMC
September 2013

Epigenetics and fetal metabolic programming: a call for integrated research on larger cohorts.

Authors:
Luigi Bouchard

Diabetes 2013 Apr;62(4):1026-8

Department of Biochemistry, Université de Sherbrooke, Sherbrooke, Quebec, Canada.

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http://dx.doi.org/10.2337/db12-1763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609562PMC
April 2013

The lipid accumulation product for the early prediction of gestational insulin resistance and glucose dysregulation.

J Womens Health (Larchmt) 2013 Apr;22(4):362-7

Department of Medicine, Universite´ de Montre´al, ECOGENE-21 and Lipid Clinic, Chicoutimi Hospital, Saguenay, Quebec, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627434PMC
April 2013

Fetal epigenetic programming of adipokines.

Adipocyte 2013 Jan;2(1):41-46

Department of Biochemistry; Université de Sherbrooke; Sherbrooke, QC Canada ; ECOGENE-21 and Lipid Clinic; Chicoutimi Hospital; Saguenay, QC Canada.

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http://dx.doi.org/10.4161/adip.22055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3661130PMC
January 2013

Epigenome-wide analysis in familial hypercholesterolemia identified new loci associated with high-density lipoprotein cholesterol concentration.

Epigenomics 2012 Dec;4(6):623-39

Department of Biochemistry, Université de Sherbrooke, 225 St-Vallier Street, Chicoutimi, QC, G7H 7P2, Canada.

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http://dx.doi.org/10.2217/epi.12.62DOI Listing
December 2012

Association of LIPA gene polymorphisms with obesity-related metabolic complications among severely obese patients.

Obesity (Silver Spring) 2012 Oct 7;20(10):2075-82. Epub 2012 Mar 7.

Nutraceuticals and Functional Foods Institute, Laval University, Quebec City, Quebec, Canada.

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http://dx.doi.org/10.1038/oby.2012.52DOI Listing
October 2012

IGF2 DNA methylation is a modulator of newborn's fetal growth and development.

Epigenetics 2012 Oct 21;7(10):1125-32. Epub 2012 Aug 21.

Department of Pediatrics, Chicoutimi Hospital, Chicoutimi, QC, Canada.

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http://dx.doi.org/10.4161/epi.21855DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469454PMC
October 2012

Placental adiponectin gene DNA methylation levels are associated with mothers' blood glucose concentration.

Diabetes 2012 May 6;61(5):1272-80. Epub 2012 Mar 6.

Department of Biochemistry, Université de Sherbrooke, Sherbrooke, Québec, Canada.

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http://dx.doi.org/10.2337/db11-1160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331769PMC
May 2012

ABCA1 gene promoter DNA methylation is associated with HDL particle profile and coronary artery disease in familial hypercholesterolemia.

Epigenetics 2012 May 1;7(5):464-72. Epub 2012 May 1.

Department of Biochemistry, Université de Sherbrooke, Sherbrooke, QC, Canada.

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http://dx.doi.org/10.4161/epi.19633DOI Listing
May 2012

Genetic contribution to C-reactive protein levels in severe obesity.

Mol Genet Metab 2012 Mar 2;105(3):494-501. Epub 2011 Dec 2.

Nutraceuticals and Functional Foods Institute (INAF), Laval University, Québec, Canada.

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http://dx.doi.org/10.1016/j.ymgme.2011.11.198DOI Listing
March 2012

Association between olfactory receptor genes, eating behavior traits and adiposity: results from the Quebec Family Study.

Physiol Behav 2012 Feb 25;105(3):772-6. Epub 2011 Oct 25.

Department of Social and Preventive Medicine, Laval University, Quebec, Canada.

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http://dx.doi.org/10.1016/j.physbeh.2011.10.015DOI Listing
February 2012

Effects of neuromedin-β on caloric compensation, eating behaviours and habitual food intake.

Appetite 2011 Aug 16;57(1):21-7. Epub 2011 Apr 16.

Institute of Nutraceuticals and Functional Foods, Université Laval, Québec (Québec), Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S019566631100124
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http://dx.doi.org/10.1016/j.appet.2011.04.003DOI Listing
August 2011

Leptin gene epigenetic adaptation to impaired glucose metabolism during pregnancy.

Diabetes Care 2010 Nov 19;33(11):2436-41. Epub 2010 Aug 19.

Department of Medicine, Université de Montréal, Montréal, Quebec, Canada.

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http://dx.doi.org/10.2337/dc10-1024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963508PMC
November 2010

The "hypertriglyceridemic waist" phenotype and glucose intolerance in pregnancy.

CMAJ 2010 Oct 20;182(15):E722-5. Epub 2010 Sep 20.

Department of Medicine, Université de Montréal, Montreal, Canada.

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http://dx.doi.org/10.1503/cmaj.100378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2952030PMC
October 2010

Contribution of genetic and metabolic syndrome to omental adipose tissue PAI-1 gene mRNA and plasma levels in obesity.

Obes Surg 2010 Apr 2;20(4):492-9. Epub 2010 Feb 2.

Department of Medicine, ECOGENE-21 and Lipid Clinic, Chicoutimi Hospital, Université de Montréal, Saguenay, QC, Canada.

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http://dx.doi.org/10.1007/s11695-010-0079-1DOI Listing
April 2010

Association of OSBPL11 gene polymorphisms with cardiovascular disease risk factors in obesity.

Obesity (Silver Spring) 2009 Jul 26;17(7):1466-72. Epub 2009 Mar 26.

Montreal University Community Genomics Medicine Center, Chicoutimi Hospital, Université de Montreal, Chicoutimi, Québec, Canada.

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http://dx.doi.org/10.1038/oby.2009.71DOI Listing
July 2009

Comprehensive genetic analysis of the dipeptidyl peptidase-4 gene and cardiovascular disease risk factors in obese individuals.

Acta Diabetol 2009 Mar 6;46(1):13-21. Epub 2008 Aug 6.

Lipid Research Center, Laval University, 2705 Laurier Blvd (TR93), Quebec City, QC, Canada G1V 4G2.

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http://dx.doi.org/10.1007/s00592-008-0049-4DOI Listing
March 2009

Epigenomic profiling reveals DNA-methylation changes associated with major psychosis.

Am J Hum Genet 2008 Mar;82(3):696-711

Krembil Family Epigenetic Laboratory, Centre for Addiction and Mental Health, 250 College Street, Toronto, Ontario, M5T 1R8, Canada.

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http://dx.doi.org/10.1016/j.ajhg.2008.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2427301PMC
March 2008

Evidence of linkage and association with body fatness and abdominal fat on chromosome 15q26.

Obesity (Silver Spring) 2007 Aug;15(8):2061-70

Lipid Research Center, Nutraceuticals and Functional Foods Institute, Laval University, Canada.

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http://dx.doi.org/10.1038/oby.2007.245DOI Listing
August 2007

A quantitative trait locus for body fat on chromosome 1q43 in French Canadians: linkage and association studies.

Obesity (Silver Spring) 2006 Sep;14(9):1605-15

Human Genomics Laboratory, Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, LA 70808, USA.

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http://dx.doi.org/10.1038/oby.2006.185DOI Listing
September 2006

Is GAD2 on chromosome 10p12 a potential candidate gene for morbid obesity?

Nutr Rev 2005 Sep;63(9):315-9

Department of Biostatistics, Section on Statistical Genetics, University of Alabama, Birmingham 35294, USA.

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http://dx.doi.org/10.1111/j.1753-4887.2005.tb00147.xDOI Listing
September 2005

Plasminogen-activator inhibitor-1 polymorphisms are associated with obesity and fat distribution in the Quebec Family Study: evidence of interactions with menopause.

Menopause 2005 Mar;12(2):136-43

Division of Kinesiology, Department of Social and Preventive Medicine, Faculty of Medicine, Laval University, Quebec, Canada.

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March 2005

Neuromedin beta: a strong candidate gene linking eating behaviors and susceptibility to obesity.

Am J Clin Nutr 2004 Dec;80(6):1478-86

Division of Kinesiology, Department of Social and Preventive Medicine, Faculty of Medicine, Lipid Research Centre, Canada.

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http://dx.doi.org/10.1093/ajcn/80.6.1478DOI Listing
December 2004

Long-term adiposity changes are related to a glucocorticoid receptor polymorphism in young females.

J Clin Endocrinol Metab 2003 Jul;88(7):3141-5

Division of Kinesiology, Department of Social and Preventive Medicine, Faculty of Medicine, Laval University, Ste-Foy, Québec, Canada, G1K 7P4.

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http://dx.doi.org/10.1210/jc.2002-021521DOI Listing
July 2003