Ludwig Lehle

Ludwig Lehle

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Ludwig Lehle

Ludwig Lehle

Publications by authors named "Ludwig Lehle"

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27Publications

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C. elegans DPY-19 is a C-mannosyltransferase glycosylating thrombospondin repeats.

Mol Cell 2013 Apr 4;50(2):295-302. Epub 2013 Apr 4.

Department of Cellular Chemistry, Hannover Medical School, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany.

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http://dx.doi.org/10.1016/j.molcel.2013.03.003DOI Listing
April 2013

Identification of alg3 in the mushroom-forming fungus Schizophyllum commune and analysis of the Δalg3 knockout mutant.

Glycobiology 2013 Feb 20;23(2):147-54. Epub 2012 Sep 20.

Microbiology and Kluyver Centre for Genomics of Industrial Fermentations, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/glycob/cws135DOI Listing
February 2013

Defining the phenotype in congenital disorder of glycosylation due to ALG1 mutations.

Pediatrics 2012 Oct 10;130(4):e1034-9. Epub 2012 Sep 10.

Department of Pediatrics at the Institute for Genetic and Metabolic Diseases, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1542/peds.2011-2711DOI Listing
October 2012

More than 40 years of glycobiology in Regensburg.

Biochem Biophys Res Commun 2012 Aug;425(3):578-82

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http://dx.doi.org/10.1016/j.bbrc.2012.08.001DOI Listing
August 2012

The essential endoplasmic reticulum chaperone Rot1 is required for protein N- and O-glycosylation in yeast.

Glycobiology 2012 Jul 4;22(7):939-47. Epub 2012 Apr 4.

Department of Cell Biology and Plant Biochemistry, University of Regensburg, Regensburg, Germany.

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https://academic.oup.com/glycob/article-lookup/doi/10.1093/g
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http://dx.doi.org/10.1093/glycob/cws068DOI Listing
July 2012

A severe human metabolic disease caused by deficiency of the endoplasmatic mannosyltransferase hALG11 leads to congenital disorder of glycosylation-Ip.

Hum Mol Genet 2010 Apr 15;19(8):1413-24. Epub 2010 Jan 15.

Center for Child and Adolescent Medicine, Center for Metabolic Diseases Heidelberg, Department I, Im Neuenheimer Feld 153, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.1093/hmg/ddq016DOI Listing
April 2010

The yeast oligosaccharyltransferase complex can be replaced by STT3 from Leishmania major.

Glycobiology 2009 Feb 25;19(2):160-71. Epub 2008 Oct 25.

Lehrstuhl für Zellbiologie und Pflanzenphysiologie, Universität Regensburg, Regensburg, Germany.

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https://academic.oup.com/glycob/article-lookup/doi/10.1093/g
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http://dx.doi.org/10.1093/glycob/cwn118DOI Listing
February 2009

Kex1 protease is involved in yeast cell death induced by defective N-glycosylation, acetic acid, and chronological aging.

J Biol Chem 2008 Jul 12;283(27):19151-63. Epub 2008 May 12.

Lehrstuhl für Zellbiologie und Pflanzenphysiologie, Universität Regensburg, Universitätstrasse 31, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1074/jbc.M801303200DOI Listing
July 2008

Protein glycosylation, conserved from yeast to man: a model organism helps elucidate congenital human diseases.

Angew Chem Int Ed Engl 2006 Oct;45(41):6802-18

Lehrstuhl für Zellbiologie und Pflanzenphysiologie, Universität Regensburg, Universitätstrasse 31, 93053 Regensburg, Germany.

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http://doi.wiley.com/10.1002/anie.200601645
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http://dx.doi.org/10.1002/anie.200601645DOI Listing
October 2006

Pir proteins of Saccharomyces cerevisiae are attached to beta-1,3-glucan by a new protein-carbohydrate linkage.

J Biol Chem 2006 Apr 22;281(17):11523-9. Epub 2006 Feb 22.

Lehrstuhl für Zellbiologie und Pflanzenphysiologie, Universitaet Regensburg, Universitaetsstrasse 31, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1074/jbc.M600314200DOI Listing
April 2006

Defects in N-glycosylation induce apoptosis in yeast.

Mol Microbiol 2006 Feb;59(3):765-78

Lehrstuhl für Zellbiologie und Pflanzenphysiologie, Universität Regensburg, Regensburg, Germany.

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http://dx.doi.org/10.1111/j.1365-2958.2005.04981.xDOI Listing
February 2006

Yeast oligosaccharyltransferase consists of two functionally distinct sub-complexes, specified by either the Ost3p or Ost6p subunit.

FEBS Lett 2005 Dec 10;579(29):6564-8. Epub 2005 Nov 10.

Lehrstuhl für Zellbiologie und Pflanzenphysiologie, Universität Regensburg, Universitätsstrasse 31, 93053 Regensburg, Germany.

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http://doi.wiley.com/10.1016/j.febslet.2005.10.063
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http://dx.doi.org/10.1016/j.febslet.2005.10.063DOI Listing
December 2005

Biosynthesis of lipid-linked oligosaccharides in Saccharomyces cerevisiae: Alg13p and Alg14p form a complex required for the formation of GlcNAc(2)-PP-dolichol.

J Biol Chem 2005 Oct 12;280(41):34500-6. Epub 2005 Aug 12.

Lehrstuhl für Zellbiologie und Pflanzenphysiologie, Universität Regensburg, Universitätsstrasse 31, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1074/jbc.M506358200DOI Listing
October 2005

Deficiency of GDP-Man:GlcNAc2-PP-dolichol mannosyltransferase causes congenital disorder of glycosylation type Ik.

Am J Hum Genet 2004 Mar 16;74(3):472-81. Epub 2004 Feb 16.

Universität Regensburg, Lehrstuhl für Zellbiologie und Pflanzenphysiologie, Regensburg, Germany.

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http://dx.doi.org/10.1086/382492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182261PMC
March 2004

A new type of congenital disorders of glycosylation (CDG-Ii) provides new insights into the early steps of dolichol-linked oligosaccharide biosynthesis.

J Biol Chem 2003 Jun 8;278(25):22498-505. Epub 2003 Apr 8.

Georg-August-Universität Göttingen, Biochemie II, Heinrich-Düker-Weg 12, D-37073 Göttingen, Germany.

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http://dx.doi.org/10.1074/jbc.M302850200DOI Listing
June 2003

The auxin-induced maize gene ZmSAUR2 encodes a short-lived nuclear protein expressed in elongating tissues.

J Biol Chem 2003 Jun 14;278(26):23936-43. Epub 2003 Apr 14.

Lehrstuhl für Zellbiologie und Pflanzenphysiologie, Universität Regensburg, Universitätsstrasse 31, 93053 Regensburg, Germany.

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http://dx.doi.org/10.1074/jbc.M212585200DOI Listing
June 2003

Overexpression of GDP-mannose pyrophosphorylase in Saccharomyces cerevisiae corrects defects in dolichol-linked saccharide formation and protein glycosylation.

Biochim Biophys Acta 2003 Apr;1621(1):22-30

Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Pawinskiego 5a, 02 106, Warsaw, Poland.

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http://dx.doi.org/10.1016/s0304-4165(03)00026-6DOI Listing
April 2003

Deficiency of dolichyl-P-Man:Man7GlcNAc2-PP-dolichyl mannosyltransferase causes congenital disorder of glycosylation type Ig.

Biochem J 2002 Oct;367(Pt 1):195-201

Georg-August-Universität zu Göttingen, Abteilung Biochemie II, Heinrich-Düker-Weg 12, D-37073 Göttingen, Germany.

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http://dx.doi.org/10.1042/BJ20020794DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1222867PMC
October 2002