Publications by authors named "Ludovico Cantuti-Castelvetri"

20Publications

Diet-dependent regulation of TGFβ impairs reparative innate immune responses after demyelination.

Authors:
Mar Bosch-Queralt Ludovico Cantuti-Castelvetri Alkmini Damkou Martina Schifferer Kai Schlepckow Ioannis Alexopoulos Dieter Lütjohann Christian Klose Lenka Vaculčiaková Takahiro Masuda Marco Prinz Kathryn M Monroe Gilbert Di Paolo Joseph W Lewcock Christian Haass Mikael Simons

Nat Metab 2021 Feb 18;3(2):211-227. Epub 2021 Feb 18.

Institute of Neuronal Cell Biology, Technical University Munich, Munich, Germany.

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February 2021

White matter aging drives microglial diversity.

Authors:
Shima Safaiyan Simon Besson-Girard Tuğberk Kaya Ludovico Cantuti-Castelvetri Lu Liu Hao Ji Martina Schifferer Garyfallia Gouna Fumere Usifo Nirmal Kannaiyan Dirk Fitzner Xianyuan Xiang Moritz J Rossner Matthias Brendel Ozgun Gokce Mikael Simons

Neuron 2021 Feb 11. Epub 2021 Feb 11.

Institute of Neuronal Cell Biology, Technical University Munich, 80802 Munich, Germany; German Center for Neurodegenerative Diseases (DZNE), 81377 Munich, Germany; Munich Cluster of Systems Neurology (SyNergy), 81377 Munich, Germany. Electronic address:

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February 2021

Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis.

Authors:
Stefan A Berghoff Lena Spieth Ting Sun Leon Hosang Lennart Schlaphoff Constanze Depp Tim Düking Jan Winchenbach Jonathan Neuber David Ewers Patricia Scholz Franziska van der Meer Ludovico Cantuti-Castelvetri Andrew O Sasmita Martin Meschkat Torben Ruhwedel Wiebke Möbius Roman Sankowski Marco Prinz Inge Huitinga Michael W Sereda Francesca Odoardi Till Ischebeck Mikael Simons Christine Stadelmann-Nessler Julia M Edgar Klaus-Armin Nave Gesine Saher

Nat Neurosci 2021 Jan 21;24(1):47-60. Epub 2020 Dec 21.

Department of Neurogenetics, Max Planck Institute of Experimental Medicine, Göttingen, Germany.

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January 2021

Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity.

Authors:
Ludovico Cantuti-Castelvetri Ravi Ojha Liliana D Pedro Minou Djannatian Jonas Franz Suvi Kuivanen Franziska van der Meer Katri Kallio Tuğberk Kaya Maria Anastasina Teemu Smura Lev Levanov Leonora Szirovicza Allan Tobi Hannimari Kallio-Kokko Pamela Österlund Merja Joensuu Frédéric A Meunier Sarah J Butcher Martin Sebastian Winkler Brit Mollenhauer Ari Helenius Ozgun Gokce Tambet Teesalu Jussi Hepojoki Olli Vapalahti Christine Stadelmann Giuseppe Balistreri Mikael Simons

Science 2020 11 20;370(6518):856-860. Epub 2020 Oct 20.

Institute of Neuronal Cell Biology, Technical University Munich, Munich, Germany.

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November 2020

Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region.

Authors:
Kai Schlepckow Kathryn M Monroe Gernot Kleinberger Ludovico Cantuti-Castelvetri Samira Parhizkar Dan Xia Michael Willem Georg Werner Nadine Pettkus Bettina Brunner Alice Sülzen Brigitte Nuscher Heike Hampel Xianyuan Xiang Regina Feederle Sabina Tahirovic Joshua I Park Rachel Prorok Cathal Mahon Chun-Chi Liang Ju Shi Do Jin Kim Hanna Sabelström Fen Huang Gilbert Di Paolo Mikael Simons Joseph W Lewcock Christian Haass

EMBO Mol Med 2020 04 10;12(4):e11227. Epub 2020 Mar 10.

German Center for Neurodegenerative Diseases (DZNE) Munich, Munich, Germany.

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April 2020

Pro-inflammatory activation following demyelination is required for myelin clearance and oligodendrogenesis.

Authors:
Maria Inês Cunha Minhui Su Ludovico Cantuti-Castelvetri Stephan A Müller Martina Schifferer Minou Djannatian Ioannis Alexopoulos Franziska van der Meer Anne Winkler Tjakko J van Ham Bettina Schmid Stefan F Lichtenthaler Christine Stadelmann Mikael Simons

J Exp Med 2020 05;217(5)

Institute of Neuronal Cell Biology, Technical University Munich, Munich, Germany.

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May 2020

Oligodendrocytes as A New Therapeutic Target in Schizophrenia: From Histopathological Findings to Neuron-Oligodendrocyte Interaction.

Authors:
Florian J Raabe Lenka Slapakova Moritz J Rossner Ludovico Cantuti-Castelvetri Mikael Simons Peter G Falkai Andrea Schmitt

Cells 2019 11 23;8(12). Epub 2019 Nov 23.

Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Nussbaumstrasse 7, 80336 Munich, Germany.

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November 2019

Polygenic burden associated to oligodendrocyte precursor cells and radial glia influences the hippocampal volume changes induced by aerobic exercise in schizophrenia patients.

Authors:
Sergi Papiol Daniel Keeser Alkomiet Hasan Thomas Schneider-Axmann Florian Raabe Franziska Degenhardt Moritz J Rossner Heike Bickeböller Ludovico Cantuti-Castelvetri Mikael Simons Thomas Wobrock Andrea Schmitt Berend Malchow Peter Falkai

Transl Psychiatry 2019 11 11;9(1):284. Epub 2019 Nov 11.

Department of Psychiatry, University Hospital, Nussbaumstrasse 7, 80336, Munich, Germany.

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November 2019

Association between altered hippocampal oligodendrocyte number and neuronal circuit structures in schizophrenia: a postmortem analysis.

Authors:
Peter Falkai Florian Raabe Bernhard Bogerts Thomas Schneider-Axmann Berend Malchow Laura Tatsch Verena Huber Lenka Slapakova Henrik Dobrowolny Christoph Schmitz Ludovico Cantuti-Castelvetri Mikael Simons Johann Steiner Andrea Schmitt

Eur Arch Psychiatry Clin Neurosci 2020 Jun 24;270(4):413-424. Epub 2019 Sep 24.

Department of Psychiatry and Psychotherapy, University Hospital, Ludwig Maximilian University Munich, Nussbaumstrasse 7, 80336, Munich, Germany.

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June 2020

A new role for oligodendrocytes and myelination in schizophrenia and affective disorders?

Authors:
Andrea Schmitt Mikael Simons Ludovico Cantuti-Castelvetri Peter Falkai

Eur Arch Psychiatry Clin Neurosci 2019 06;269(4):371-372

Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, 80336, Munich, Germany.

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June 2019

Mononuclear phagocytes locally specify and adapt their phenotype in a multiple sclerosis model.

Authors:
Giuseppe Locatelli Delphine Theodorou Arek Kendirli Marta Joana Costa Jordão Ori Staszewski Kshiti Phulphagar Ludovico Cantuti-Castelvetri Athanasios Dagkalis Alain Bessis Mikael Simons Felix Meissner Marco Prinz Martin Kerschensteiner

Nat Neurosci 2018 09 20;21(9):1196-1208. Epub 2018 Aug 20.

Institute of Clinical Neuroimmunology, University Hospital, Ludwig-Maximilians University Munich, Munich, Germany.

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September 2018

Defective cholesterol clearance limits remyelination in the aged central nervous system.

Authors:
Ludovico Cantuti-Castelvetri Dirk Fitzner Mar Bosch-Queralt Marie-Theres Weil Minhui Su Paromita Sen Torben Ruhwedel Miso Mitkovski George Trendelenburg Dieter Lütjohann Wiebke Möbius Mikael Simons

Science 2018 02 4;359(6376):684-688. Epub 2018 Jan 4.

Max Planck Institute of Experimental Medicine, 37075 Göttingen, Germany.

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February 2018

BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions.

Authors:
Maryam K Fard Franziska van der Meer Paula Sánchez Ludovico Cantuti-Castelvetri Sunit Mandad Sarah Jäkel Eugenio F Fornasiero Sebastian Schmitt Marc Ehrlich Laura Starost Tanja Kuhlmann Christina Sergiou Verena Schultz Claudia Wrzos Wolfgang Brück Henning Urlaub Leda Dimou Christine Stadelmann Mikael Simons

Sci Transl Med 2017 Dec;9(419)

Max Planck Institute for Experimental Medicine, 37075 Göttingen, Germany.

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December 2017

Synaptic failure: The achilles tendon of sphingolipidoses.

Authors:
Ludovico Cantuti-Castelvetri Ernesto R Bongarzone

J Neurosci Res 2016 11;94(11):1031-6

Department of Anatomy and Cell Biology, College of Medicine, University of Illinois at Chicago, Chicago, Illinois.

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November 2016

Mechanism of neuromuscular dysfunction in Krabbe disease.

Authors:
Ludovico Cantuti-Castelvetri Erick Maravilla Michael Marshall Tammy Tamayo Ludovic D'auria John Monge James Jeffries Tuba Sural-Fehr Aurora Lopez-Rosas Guannan Li Kelly Garcia Richard van Breemen Charles Vite Jesus Garcia Ernesto R Bongarzone

J Neurosci 2015 Jan;35(4):1606-16

Departments of Anatomy and Cell Biology,

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January 2015

Neuronal inclusions of α-synuclein contribute to the pathogenesis of Krabbe disease.

Authors:
Benjamin R Smith Marta B Santos Michael S Marshall Ludovico Cantuti-Castelvetri Aurora Lopez-Rosas Guannan Li Richard van Breemen Kumiko I Claycomb Jose I Gallea Maria S Celej Stephen J Crocker Maria I Givogri Ernesto R Bongarzone

J Pathol 2014 Apr 20;232(5):509-21. Epub 2014 Feb 20.

Department of Anatomy and Cell Biology, College of Medicine, University of Illinois, University of Illinois Chicago, Chicago, IL, 60612, USA.

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April 2014

The sphingolipid psychosine inhibits fast axonal transport in Krabbe disease by activation of GSK3β and deregulation of molecular motors.

Authors:
Ludovico Cantuti Castelvetri Maria I Givogri Amy Hebert Benjamin Smith Yuyu Song Agnieszka Kaminska Aurora Lopez-Rosas Gerardo Morfini Gustavo Pigino Mark Sands Scott T Brady Ernesto R Bongarzone

J Neurosci 2013 Jun;33(24):10048-56

Department of Anatomy and Cell Biology, University of Illinois at Chicago, Chicago, Illinois 60612, USA.

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June 2013

Psychosine induces the dephosphorylation of neurofilaments by deregulation of PP1 and PP2A phosphatases.

Authors:
Ludovico Cantuti-Castelvetri Hongling Zhu Maria I Givogri Robstein L Chidavaenzi Aurora Lopez-Rosas Ernesto R Bongarzone

Neurobiol Dis 2012 May 4;46(2):325-35. Epub 2012 Feb 4.

Department of Anatomy and Cell Biology, University of Illinois, Chicago, IL 60612, USA.

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May 2012

Peripheral neuropathy in the Twitcher mouse involves the activation of axonal caspase 3.

Authors:
Benjamin Smith Francesca Galbiati Ludovico Cantuti Castelvetri Maria I Givogri Aurora Lopez-Rosas Ernesto R Bongarzone

ASN Neuro 2011 ;3(4)

Department of Anatomy and Cell Biology, College of Medicine, University of Illinois, Chicago, USA.

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March 2012

Axonopathy is a compounding factor in the pathogenesis of Krabbe disease.

Authors:
Ludovico Cantuti Castelvetri Maria Irene Givogri Hongling Zhu Benjamin Smith Aurora Lopez-Rosas Xi Qiu Richard van Breemen Ernesto Roque Bongarzone

Acta Neuropathol 2011 Jul 4;122(1):35-48. Epub 2011 Mar 4.

Department of Anatomy and Cell Biology, College of Medicine, University of Illinois, MC512, Chicago, IL 60612, USA.

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July 2011