Ludmila Vodickova

Ludmila Vodickova

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Ludmila Vodickova

Ludmila Vodickova

Publications by authors named "Ludmila Vodickova"

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Discovery of common and rare genetic risk variants for colorectal cancer.

Authors:
Jeroen R Huyghe Stephanie A Bien Tabitha A Harrison Hyun Min Kang Sai Chen Stephanie L Schmit David V Conti Conghui Qu Jihyoun Jeon Christopher K Edlund Peyton Greenside Michael Wainberg Fredrick R Schumacher Joshua D Smith David M Levine Sarah C Nelson Nasa A Sinnott-Armstrong Demetrius Albanes M Henar Alonso Kristin Anderson Coral Arnau-Collell Volker Arndt Christina Bamia Barbara L Banbury John A Baron Sonja I Berndt Stéphane Bézieau D Timothy Bishop Juergen Boehm Heiner Boeing Hermann Brenner Stefanie Brezina Stephan Buch Daniel D Buchanan Andrea Burnett-Hartman Katja Butterbach Bette J Caan Peter T Campbell Christopher S Carlson Sergi Castellví-Bel Andrew T Chan Jenny Chang-Claude Stephen J Chanock Maria-Dolores Chirlaque Sang Hee Cho Charles M Connolly Amanda J Cross Katarina Cuk Keith R Curtis Albert de la Chapelle Kimberly F Doheny David Duggan Douglas F Easton Sjoerd G Elias Faye Elliott Dallas R English Edith J M Feskens Jane C Figueiredo Rocky Fischer Liesel M FitzGerald David Forman Manish Gala Steven Gallinger W James Gauderman Graham G Giles Elizabeth Gillanders Jian Gong Phyllis J Goodman William M Grady John S Grove Andrea Gsur Marc J Gunter Robert W Haile Jochen Hampe Heather Hampel Sophia Harlid Richard B Hayes Philipp Hofer Michael Hoffmeister John L Hopper Wan-Ling Hsu Wen-Yi Huang Thomas J Hudson David J Hunter Gemma Ibañez-Sanz Gregory E Idos Roxann Ingersoll Rebecca D Jackson Eric J Jacobs Mark A Jenkins Amit D Joshi Corinne E Joshu Temitope O Keku Timothy J Key Hyeong Rok Kim Emiko Kobayashi Laurence N Kolonel Charles Kooperberg Tilman Kühn Sébastien Küry Sun-Seog Kweon Susanna C Larsson Cecelia A Laurie Loic Le Marchand Suzanne M Leal Soo Chin Lee Flavio Lejbkowicz Mathieu Lemire Christopher I Li Li Li Wolfgang Lieb Yi Lin Annika Lindblom Noralane M Lindor Hua Ling Tin L Louie Satu Männistö Sanford D Markowitz Vicente Martín Giovanna Masala Caroline E McNeil Marilena Melas Roger L Milne Lorena Moreno Neil Murphy Robin Myte Alessio Naccarati Polly A Newcomb Kenneth Offit Shuji Ogino N Charlotte Onland-Moret Barbara Pardini Patrick S Parfrey Rachel Pearlman Vittorio Perduca Paul D P Pharoah Mila Pinchev Elizabeth A Platz Ross L Prentice Elizabeth Pugh Leon Raskin Gad Rennert Hedy S Rennert Elio Riboli Miguel Rodríguez-Barranco Jane Romm Lori C Sakoda Clemens Schafmayer Robert E Schoen Daniela Seminara Mitul Shah Tameka Shelford Min-Ho Shin Katerina Shulman Sabina Sieri Martha L Slattery Melissa C Southey Zsofia K Stadler Christa Stegmaier Yu-Ru Su Catherine M Tangen Stephen N Thibodeau Duncan C Thomas Sushma S Thomas Amanda E Toland Antonia Trichopoulou Cornelia M Ulrich David J Van Den Berg Franzel J B van Duijnhoven Bethany Van Guelpen Henk van Kranen Joseph Vijai Kala Visvanathan Pavel Vodicka Ludmila Vodickova Veronika Vymetalkova Korbinian Weigl Stephanie J Weinstein Emily White Aung Ko Win C Roland Wolf Alicja Wolk Michael O Woods Anna H Wu Syed H Zaidi Brent W Zanke Qing Zhang Wei Zheng Peter C Scacheri John D Potter Michael C Bassik Anshul Kundaje Graham Casey Victor Moreno Goncalo R Abecasis Deborah A Nickerson Stephen B Gruber Li Hsu Ulrike Peters

Nat Genet 2019 Jan 3;51(1):76-87. Epub 2018 Dec 3.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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http://www.nature.com/articles/s41588-018-0286-6
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http://dx.doi.org/10.1038/s41588-018-0286-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358437PMC
January 2019

Base excision repair capacity as a determinant of prognosis and therapy response in colon cancer patients.

DNA Repair (Amst) 2018 Dec 1;72:77-85. Epub 2018 Oct 1.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine of the Czech Academy of Sciences, Videnska 1083, 142 20 Prague, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University and General University Hospital in Prague, Albertov 4, 128 00, Prague, Czech Republic; Biomedical Center, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 76, 323 00, Pilsen, Czech Republic. Electronic address:

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http://dx.doi.org/10.1016/j.dnarep.2018.09.006DOI Listing
December 2018

Genetic variation of acquired structural chromosomal aberrations.

Mutat Res 2018 Dec 19;836(Pt A):13-21. Epub 2018 May 19.

Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, D69120, Germany; Center for Primary Health Care Research, Lund University, Malmö, 214 28, Sweden.

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https://www.researchgate.net/publication/236938844_From_DNA_
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https://linkinghub.elsevier.com/retrieve/pii/S13835718183002
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http://dx.doi.org/10.1016/j.mrgentox.2018.05.014DOI Listing
December 2018

Bleomycin-induced chromosomal damage and shortening of telomeres in peripheral blood lymphocytes of incident cancer patients.

Genes Chromosomes Cancer 2018 02 24;57(2):61-69. Epub 2017 Nov 24.

Faculty of Medicine and Biomedical Center in Pilsen, Charles University, Pilsen, 30605, Czech Republic.

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http://dx.doi.org/10.1002/gcc.22508DOI Listing
February 2018

Genotoxic and Cytotoxic Effects in Exfoliated Buccal and Nasal Cells of Chromium and Cobalt Exposed Electroplaters.

J Toxicol Environ Health A 2017 19;80(13-15):651-660. Epub 2017 May 19.

a Department of Medicine I, Institute of Cancer Research , Medical University of Vienna , Vienna , Austria.

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http://dx.doi.org/10.1080/15287394.2017.1286918DOI Listing
October 2017

DNA and chromosomal damage in medical workers exposed to anaesthetic gases assessed by the lymphocyte cytokinesis-block micronucleus (CBMN) assay. A critical review.

Mutat Res 2016 Oct - Dec;770(Pt A):26-34. Epub 2016 Apr 8.

Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Videnska 1083, 142 00 Prague, Czech Republic; Human Genetics Foundation (HuGeF) Turin, via Nizza 52, 10126 Turin, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S13835742163002
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http://dx.doi.org/10.1016/j.mrrev.2016.04.003DOI Listing
May 2017

Polymorphisms in microRNA binding sites of mucin genes as predictors of clinical outcome in colorectal cancer patients.

Carcinogenesis 2017 01 1;38(1):28-39. Epub 2016 Nov 1.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine, 14200 Prague, Czech Republic.

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http://dx.doi.org/10.1093/carcin/bgw114DOI Listing
January 2017

Genetic variation in the major mitotic checkpoint genes associated with chromosomal aberrations in healthy humans.

Cancer Lett 2016 10 15;380(2):442-6. Epub 2016 Jul 15.

Department of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120 Heidelberg, Germany; Center for Primary Health Care Research, Lund University, Malmö, Sweden.

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https://linkinghub.elsevier.com/retrieve/pii/S03043835163040
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http://dx.doi.org/10.1016/j.canlet.2016.07.011DOI Listing
October 2016

Epigenome-wide analysis of DNA methylation reveals a rectal cancer-specific epigenomic signature.

Epigenomics 2016 09 16;8(9):1193-207. Epub 2016 Aug 16.

Department of Laboratory Medicine, Örebro University; Örebro, Sweden.

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http://dx.doi.org/10.2217/epi-2016-0044DOI Listing
September 2016

The focus on sample quality: Influence of colon tissue collection on reliability of qPCR data.

Sci Rep 2016 07 7;6:29023. Epub 2016 Jul 7.

Unit of Medical Statistics, Biometry and Bioinformatics, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Nazionale dei Tumori, Milan, Italy.

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http://dx.doi.org/10.1038/srep29023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4935944PMC
July 2016

Genotype and Haplotype Analyses of TP53 Gene in Breast Cancer Patients: Association with Risk and Clinical Outcomes.

PLoS One 2015 30;10(7):e0134463. Epub 2015 Jul 30.

Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic; Institute of Biology and Medical Genetics, First Faculty of Medicine Charles University, Prague, Czech Republic.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134463PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520609PMC
May 2016

Single nucleotide polymorphisms within interferon signaling pathway genes are associated with colorectal cancer susceptibility and survival.

PLoS One 2014 28;9(10):e111061. Epub 2014 Oct 28.

Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany; Center of Primary Health Care Research, Clinical Research Center, Lund University, Malmö, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111061PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211713PMC
January 2016

TERT gene harbors multiple variants associated with pancreatic cancer susceptibility.

Int J Cancer 2015 Nov 19;137(9):2175-83. Epub 2015 Jun 19.

Genomic Epidemiology Group, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.29590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548797PMC
November 2015

Interactions of DNA repair gene variants modulate chromosomal aberrations in healthy subjects.

Carcinogenesis 2015 Nov 8;36(11):1299-306. Epub 2015 Sep 8.

Division of Molecular Genetic Epidemiology, German Cancer Research Centre (DKFZ), 69120 Heidelberg, Germany, Center for Primary Health Care Research, Lund University, 20506 Malmö, Sweden and.

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http://dx.doi.org/10.1093/carcin/bgv127DOI Listing
November 2015

Structural chromosomal aberrations as potential risk markers in incident cancer patients.

Mutagenesis 2015 Jul 23;30(4):557-63. Epub 2015 Mar 23.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, 142 20 Prague, Czech Republic, Institute of Biology and Medical Genetics, 1st Faculty of Medicine, Charles University in Prague, 128 00 Prague, Czech Republic,

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http://dx.doi.org/10.1093/mutage/gev018DOI Listing
July 2015

Metabolic gene variants associated with chromosomal aberrations in healthy humans.

Genes Chromosomes Cancer 2015 Apr 27;54(4):260-6. Epub 2015 Jan 27.

Department of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany; Center for Primary Health Care Research, Lund University, Malmö, Sweden.

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http://dx.doi.org/10.1002/gcc.22239DOI Listing
April 2015

Telomere length in circulating lymphocytes: Association with chromosomal aberrations.

Genes Chromosomes Cancer 2015 Mar 27;54(3):194-6. Epub 2014 Nov 27.

Department of Molecular Genetic Epidemiology, German Cancer Research Center Heidelberg, (DKFZ), Im Neuenheimer Feld 580, 69121, Heidelberg, Germany; Center for Primary Health Care Research, Lund University, Malmö, Sweden.

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http://dx.doi.org/10.1002/gcc.22225DOI Listing
March 2015

HOTAIR long non-coding RNA is a negative prognostic factor not only in primary tumors, but also in the blood of colorectal cancer patients.

Carcinogenesis 2014 Jul 28;35(7):1510-5. Epub 2014 Feb 28.

Institute of Experimental Medicine, ASCR, Prague 14220, Czech Republic, Institute of Biology and Medical Genetics, First Medical Faculty, Charles University, Prague 12000, Czech Republic,

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http://dx.doi.org/10.1093/carcin/bgu055DOI Listing
July 2014

Variations in mismatch repair genes and colorectal cancer risk and clinical outcome.

Mutagenesis 2014 Jul 22;29(4):259-65. Epub 2014 Apr 22.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Videnska 1083, 14200 Prague, Czech Republic, Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University, Katerinska 32, 12800 Prague, Czech Republic.

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http://dx.doi.org/10.1093/mutage/geu014DOI Listing
July 2014

Colorectal cancer risk and patients' survival: influence of polymorphisms in genes somatically mutated in colorectal tumors.

Cancer Causes Control 2014 Jun 5;25(6):759-69. Epub 2014 Apr 5.

Department of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120, Heidelberg, Germany,

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http://dx.doi.org/10.1007/s10552-014-0379-1DOI Listing
June 2014

Chromosomal damage among medical staff occupationally exposed to volatile anesthetics, antineoplastic drugs, and formaldehyde.

Scand J Work Environ Health 2013 Nov 22;39(6):618-30. Epub 2013 Mar 22.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine Academy of Sciences of the Czech Republic, Videnska 1083, 14200 Prague, Czech Republic.

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http://dx.doi.org/10.5271/sjweh.3358DOI Listing
November 2013

Genetic variants in C-type lectin genes are associated with colorectal cancer susceptibility and clinical outcome.

Int J Cancer 2013 Nov 29;133(10):2325-33. Epub 2013 May 29.

Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.28251DOI Listing
November 2013

Variation within 3'-UTRs of base excision repair genes and response to therapy in colorectal cancer patients: A potential modulation of microRNAs binding.

Clin Cancer Res 2013 Nov 13;19(21):6044-56. Epub 2013 Sep 13.

Authors' Affiliations: Human Genetics Foundation Torino; Department of Medical Sciences, University of Turin, Turin; Department of Biology, University of Pisa, Pisa; Laboratory of Computational Oncology, Center for Integrated Biology (CIBIO), University of Trento, Trento, Italy; Department of Molecular Biology of Cancer, Institute of Experimental Medicine; Departments of Surgery and Oncology, Thomayer Hospital; Institute of Biology and Department of Medical Genetics; and Department of Oncology, First Faculty of Medicine, Charles University, Prague, Czech Republic.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0314DOI Listing
November 2013

Evaluation of tumor suppressor gene expressions and aberrant methylation in the colon of cancer-induced rats: a pilot study.

Mol Biol Rep 2013 Oct 25;40(10):5921-9. Epub 2013 Sep 25.

Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Videnska 1083, 14200, Prague 4, Czech Republic.

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http://dx.doi.org/10.1007/s11033-013-2699-8DOI Listing
October 2013

Differences in nucleotide excision repair capacity between newly diagnosed colorectal cancer patients and healthy controls.

Mutagenesis 2012 Mar;27(2):225-32

Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Academy of Science of the Czech Republic, Videnska 1083, 14220 Prague, Czech Republic.

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http://dx.doi.org/10.1093/mutage/ger088DOI Listing
March 2012

Variation in the vitamin D receptor gene is not associated with risk of colorectal cancer in the Czech Republic.

J Gastrointest Cancer 2011 Sep;42(3):149-54

Department of Clinical Medicine, Trinity College Centre for Health Sciences, Adelaide and Meath Hospital, Dublin 24, Ireland.

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http://dx.doi.org/10.1007/s12029-010-9168-6DOI Listing
September 2011

DNA damage and nucleotide excision repair capacity in healthy individuals.

Environ Mol Mutagen 2011 Aug 25;52(7):511-7. Epub 2011 Apr 25.

Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Academy of Science of the Czech Republic, Prague.

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http://dx.doi.org/10.1002/em.20650DOI Listing
August 2011

Chromosomal damage in peripheral blood lymphocytes of newly diagnosed cancer patients and healthy controls.

Carcinogenesis 2010 Jul 9;31(7):1238-41. Epub 2010 Mar 9.

Department of molecular biology of cancer, Institute of Experimental Medicine, Academy of Science of Czech Republic, Videnska 1083, 14200 Prague 4, Czech Republic.

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http://dx.doi.org/10.1093/carcin/bgq056DOI Listing
July 2010

Genetic variants in selenoprotein genes increase risk of colorectal cancer.

Carcinogenesis 2010 Jun 8;31(6):1074-9. Epub 2010 Apr 8.

Institute for Cell and Molecular Biosciences and Human Nutrition Research Centre, The Medical School, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.

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https://academic.oup.com/carcin/article-lookup/doi/10.1093/c
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http://dx.doi.org/10.1093/carcin/bgq076DOI Listing
June 2010

Biomarkers of nucleic acid oxidation, polymorphism in, and expression of, hOGG1 gene in styrene-exposed workers.

Toxicol Lett 2009 Oct 27;190(1):41-7. Epub 2009 Jun 27.

National Institute of Occupational Safety and Prevention (ISPESL), Research Center at the University of Parma, Parma, Italy.

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http://dx.doi.org/10.1016/j.toxlet.2009.06.862DOI Listing
October 2009

Genetic variation in adipokine genes and risk of colorectal cancer.

Eur J Endocrinol 2009 Jun 9;160(6):933-40. Epub 2009 Mar 9.

Division of Molecular Genetic Epidemiology C050, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1530/EJE-09-0039DOI Listing
June 2009

NBN 657del5 heterozygous mutations and colorectal cancer risk in the Czech Republic.

Mutat Res 2009 Jun 22;666(1-2):64-7. Epub 2009 Apr 22.

Institute of Experimental Medicine, Academy of Sciences of Czech Republic, Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.mrfmmm.2009.04.004DOI Listing
June 2009

Excretion of urinary N7 guanine and N3 adenine DNA adducts in mice after inhalation of styrene.

Toxicol Lett 2009 Jan 25;184(1):33-7. Epub 2008 Oct 25.

RE&D VUFB, Podebradská 186, CZ-180 66 Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.toxlet.2008.10.010DOI Listing
January 2009

Chromosomal aberrations in tire plant workers and interaction with polymorphisms of biotransformation and DNA repair genes.

Mutat Res 2008 May 4;641(1-2):36-42. Epub 2008 Mar 4.

Department of Medical Biology, Comenius University Bratislava, Jessenius Faculty of Medicine, Malá hora 4, 03754 Martin, Slovak Republic.

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http://dx.doi.org/10.1016/j.mrfmmm.2008.02.007DOI Listing
May 2008

Insulin pathway related genes and risk of colorectal cancer: INSR promoter polymorphism shows a protective effect.

Endocr Relat Cancer 2007 Sep;14(3):733-40

Division of Molecular Genetic Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

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https://erc.bioscientifica.com/view/journals/erc/14/3/014073
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http://dx.doi.org/10.1677/ERC-07-0107DOI Listing
September 2007

Association of DNA repair polymorphisms with DNA repair functional outcomes in healthy human subjects.

Carcinogenesis 2007 Mar 6;28(3):657-64. Epub 2006 Oct 6.

Institute of Experimental Medicine, Videnska 1083, 14200, Academy of Sciences of the Czech Republic, Prague, Czech Republic.

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http://dx.doi.org/10.1093/carcin/bgl187DOI Listing
March 2007

Styrene metabolism, genotoxicity, and potential carcinogenicity.

Drug Metab Rev 2006 ;38(4):805-53

Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Prague, Czech Republic.

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http://dx.doi.org/10.1080/03602530600952222 DOI Listing
January 2007

Chromosomal damage and polymorphisms of DNA repair genes XRCC1 and XRCC3 in workers exposed to cytostatics.

Neuro Endocrinol Lett 2006 Dec;27 Suppl 2:57-60

Department of Medical Biology, Comenius University, Jessenius Faculty of Medicine Martin, Slovakia.

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December 2006

Micronuclei, DNA single-strand breaks and DNA-repair activity in mice exposed to 1,3-butadiene by inhalation.

Mutat Res 2006 Sep 23;608(1):49-57. Epub 2006 Jun 23.

Institute of Experimental Medicine, Academy of Sciences of Czech Republic, Videnska 1083, 14220 Prague 4, Czech Republic.

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http://dx.doi.org/10.1016/j.mrgentox.2006.05.003DOI Listing
September 2006

7-Alkylguanine adduct levels in urine, lungs and liver of mice exposed to styrene by inhalation.

Toxicol Appl Pharmacol 2006 Jan 8;210(1-2):1-8. Epub 2005 Jun 8.

Institute of Experimental Medicine, Academy of Sciences of Czech Republic, Videnská 1083, 14 220 Prague 4, Czech Republic.

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http://dx.doi.org/10.1016/j.taap.2005.04.020DOI Listing
January 2006

New aspects in the biomonitoring of occupational exposure to styrene.

Int Arch Occup Environ Health 2002 Oct 23;75 Suppl:S75-85. Epub 2002 Jul 23.

Institute of Experimental Medicine, Academy of Sciences of the Czech Republic, Vídenská 1083, 14220 Prague 4, Czech Republic.

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http://dx.doi.org/10.1007/s00420-002-0357-xDOI Listing
October 2002