Publications by authors named "Ludger Klein-Hitpass"

100Publications

Mutations in PIGA cause a CD52-/GPI-anchor-deficient phenotype complicating alemtuzumab treatment in T-cell prolymphocytic leukemia.

Eur J Haematol 2020 Sep 2. Epub 2020 Sep 2.

Department of Hematology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1111/ejh.13511DOI Listing
September 2020

Mesenchymal Stem Cells Isolated from the Anterior Cruciate Ligament: Characterization and Comparison of Cells from Young and Old Donors.

Knee Surg Relat Res 2018 Sep;30(3):193-205

Department of Orthopaedic Surgery, Koenig-Ludwig-Haus, Center for Musculoskeletal Research, Julius-Maximilians-University Wuerzburg, Wuerzburg, Germany.

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http://dx.doi.org/10.5792/ksrr.17.067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122945PMC
September 2018

Locus-Specific DNA Methylation Analysis by Targeted Deep Bisulfite Sequencing.

Methods Mol Biol 2018 ;1767:351-366

Institute of Human Genetics, University of Duisburg-Essen, University Hospital Essen, Essen, Germany.

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http://dx.doi.org/10.1007/978-1-4939-7774-1_19DOI Listing
February 2019

A novel physiological role for cardiac myoglobin in lipid metabolism.

Sci Rep 2017 02 23;7:43219. Epub 2017 Feb 23.

University Hospital Essen, Medical Faculty, West German Heart and Vascular Center, Department of Cardiology and Department of Angiology, Hufelandstr. 55, 45147 Essen, Germany.

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http://dx.doi.org/10.1038/srep43219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322402PMC
February 2017

OTX2 Defines a Subgroup of Atypical Teratoid Rhabdoid Tumors With Close Relationship to Choroid Plexus Tumors.

J Neuropathol Exp Neurol 2017 01;76(1):32-38

Institute of Neuropathology, University of Bonn Medical Center, Bonn, Germany.

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https://academic.oup.com/jnen/article-lookup/doi/10.1093/jne
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http://dx.doi.org/10.1093/jnen/nlw101DOI Listing
January 2017

Shorter telomeres correlate with an increase in the number of uniparental disomies in patients with chronic lymphocytic leukemia.

Leuk Lymphoma 2016 12;57(3):590-5. Epub 2015 Oct 12.

c Experimental Haematology, Department of Clinical Research , University Bern , Switzerland , and.

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http://dx.doi.org/10.3109/10428194.2015.1076929DOI Listing
December 2016

Recurrent alterations of TNFAIP3 (A20) in T-cell large granular lymphocytic leukemia.

Int J Cancer 2016 Jan 30;138(1):121-4. Epub 2015 Jul 30.

Institute of Cell Biology (Cancer Research), Medical Faculty, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1002/ijc.29697DOI Listing
January 2016

Absence of telomerase reverse transcriptase promoter mutations in neuroblastoma.

Biomed Rep 2015 Jul 13;3(4):443-446. Epub 2015 May 13.

Department of Pediatric Oncology and Hematology, University Children's Hospital Essen, D-45122 Essen, Germany ; German Consortium for Translational Cancer Research (DKTK), Partner Site Essen/Duesseldorf, D-45122 Essen, Germany ; German Cancer Research Center (DKFZ), D-69120 Heidelberg, Germany ; Translational Neuro-Oncology, West German Cancer Center (WTZ), University Hospital Essen, D-45147 Essen, Germany ; Centre for Medical Biotechnology, University Duisburg-Essen, D-45147 Essen, Germany.

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http://dx.doi.org/10.3892/br.2015.463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486810PMC
July 2015

Functional abnormalities and changes in gene expression in fibroblasts and macrophages from the bone marrow of patients with acute myeloid leukemia.

Int J Hematol 2015 Sep 28;102(3):278-88. Epub 2015 Jun 28.

Department of Hematology, University Hospital Essen, Hufelandstraße 55, 45147, Essen, Germany.

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http://dx.doi.org/10.1007/s12185-015-1833-xDOI Listing
September 2015

Characterization of bursa subacromialis-derived mesenchymal stem cells.

Stem Cell Res Ther 2015 Jun 3;6:114. Epub 2015 Jun 3.

Julius-Maximilians-University Würzburg, Department of Orthopaedic Surgery, König-Ludwig-Haus, Orthopaedic Center for Musculoskeletal Research, Julius-Maximilians-University Würzburg, Brettreichstr. 11, D - 97074, Würzburg, Germany.

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http://dx.doi.org/10.1186/s13287-015-0104-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4479225PMC
June 2015

Overexpression of tissue-nonspecific alkaline phosphatase increases the expression of neurogenic differentiation markers in the human SH-SY5Y neuroblastoma cell line.

Bone 2015 Oct 29;79:150-61. Epub 2015 May 29.

Children's Hospital, Section of Pediatric Rheumatology and Osteology, University of Wuerzburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2015.05.033DOI Listing
October 2015

Resveratrol induces apoptosis and alters gene expression in human fibrosarcoma cells.

Anticancer Res 2015 Feb;35(2):767-74

Department of Plastic Surgery, Burn Center, Hand Center, Sarcoma Reference Center, BG University Hospital Bergmannsheil Bochum, Bochum, Germany.

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February 2015

Pro‑apoptotic effects of pycnogenol on HT1080 human fibrosarcoma cells.

Int J Oncol 2015 Apr 27;46(4):1629-36. Epub 2015 Jan 27.

Department of Plastic Surgery, Burn Center, Hand Center, Sarcoma Reference Center, BG‑University Hospital Bergmannsheil, Ruhr‑University Bochum, D‑44789 Bochum, Germany.

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http://dx.doi.org/10.3892/ijo.2015.2854DOI Listing
April 2015

High-resolution genomic analysis does not qualify atypical plexus papilloma as a separate entity among choroid plexus tumors.

J Neuropathol Exp Neurol 2015 Feb;74(2):110-20

From the Institute of Neuropathology, University of Bonn Medical Center, Bonn (ASJ, MG, DD, AzM, TP); Department of Pediatric Neurosurgery, Asklepios Children's Clinic Sankt Augustin, Sankt Augustin (MM-J); Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg (SH, UK); and Department of Cell Biology (Tumor Research), University of Duisburg-Essen, Essen (LK-H), Germany; and Department of Pediatric Hematology/Oncology and Blood and Marrow Transplantation, Cleveland Clinic, Cleveland, Ohio (JEW).

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http://dx.doi.org/10.1097/NEN.0000000000000154DOI Listing
February 2015

WISP 1 is an important survival factor in human mesenchymal stromal cells.

Gene 2014 Nov 6;551(2):243-54. Epub 2014 Sep 6.

Orthopedic Center for Musculoskeletal Research, University of Würzburg, Germany.

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http://dx.doi.org/10.1016/j.gene.2014.09.002DOI Listing
November 2014

Interference of peritoneal dialysis fluids with cell cycle mechanisms.

Perit Dial Int 2015 May-Jun;35(3):259-74. Epub 2014 Jul 31.

University Hospital for Pediatrics & Adolescent Medicine, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.3747/pdi.2013.00010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4443985PMC
April 2016

Supratentorial ependymomas of childhood carry C11orf95-RELA fusions leading to pathological activation of the NF-κB signaling pathway.

Acta Neuropathol 2014 Apr 22;127(4):609-11. Epub 2014 Feb 22.

Department of Neuropathology, University of Bonn, Sigmund-Freud-St. 25, 53105, Bonn, Germany,

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http://dx.doi.org/10.1007/s00401-014-1264-4DOI Listing
April 2014

microRNA expression and its potential role in cardioprotection by ischemic postconditioning in pigs.

Pflugers Arch 2014 Oct 5;466(10):1953-61. Epub 2014 Jan 5.

Institute for Pathophysiology, University of Essen Medical School, Essen, Germany.

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http://dx.doi.org/10.1007/s00424-013-1429-3DOI Listing
October 2014

Uncovering the cellular and molecular changes in tendon stem/progenitor cells attributed to tendon aging and degeneration.

Aging Cell 2013 Dec 22;12(6):988-99. Epub 2013 Jul 22.

Department of Surgery, Experimental Surgery and Regenerative Medicine, Ludwig Maximilians University Munich, Nussbaumstr. 20, 80336, Munich, Germany.

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http://doi.wiley.com/10.1111/acel.12124
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http://dx.doi.org/10.1111/acel.12124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225469PMC
December 2013

FTO levels affect RNA modification and the transcriptome.

Eur J Hum Genet 2013 Mar 8;21(3):317-23. Epub 2012 Aug 8.

Institut für Humangenetik, Universitätsklinikum Essen, Essen, Germany.

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http://www.nature.com/articles/ejhg2012168
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http://dx.doi.org/10.1038/ejhg.2012.168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573201PMC
March 2013

Krüppel-like factors KLF2 and 6 and Ki-67 are direct targets of zoledronic acid in MCF-7 cells.

Bone 2012 Mar 7;50(3):723-32. Epub 2011 Dec 7.

Orthopedic Center for Musculoskeletal Research, University of Würzburg, Brettreichstrasse 11, 97074 Würzburg, Germany.

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http://dx.doi.org/10.1016/j.bone.2011.11.025DOI Listing
March 2012

A systematic analysis of the 3'UTR of HNF4A mRNA reveals an interplay of regulatory elements including miRNA target sites.

PLoS One 2011 30;6(11):e27438. Epub 2011 Nov 30.

Institut für Zellbiologie (Tumorforschung), Universitätsklinikum Essen, Universität Duisburg-Essen, Essen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0027438PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227676PMC
April 2012

Miz-1 is required to coordinate the expression of TCRbeta and p53 effector genes at the pre-TCR "beta-selection" checkpoint.

J Immunol 2011 Sep 12;187(6):2982-92. Epub 2011 Aug 12.

Institut de Recherches Cliniques de Montréal, Montréal, Québec H2W 1R7, Canada.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1101451
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http://dx.doi.org/10.4049/jimmunol.1101451DOI Listing
September 2011

Genotype-phenotype correlations in patients with retinoblastoma and interstitial 13q deletions.

Eur J Hum Genet 2011 Sep 20;19(9):947-58. Epub 2011 Apr 20.

Institut für Humangenetik, Universitätsklinikum Essen, Philipp-Rosenthal-Straße 55, Leipzig, Germany.

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http://dx.doi.org/10.1038/ejhg.2011.58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179359PMC
September 2011

Loss at chromosome arm 16q in retinoblastoma: confirmation of the association with diffuse vitreous seeding and refinement of the recurrently deleted region.

Genes Chromosomes Cancer 2011 May 8;50(5):327-37. Epub 2011 Feb 8.

Department of Neuroanatomy, Institute for Anatomy, University of Duisburg-Essen, Hufelandstrasse 55, Essen D-45122, Germany.

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http://dx.doi.org/10.1002/gcc.20857DOI Listing
May 2011

Gene dosage effects in chronic lymphocytic leukemia.

Cancer Genet Cytogenet 2010 Dec;203(2):149-60

Department of Hematology, Medical Faculty, University of Duisburg-Essen, Hufelandstraße 55, 45122 Essen, Germany.

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http://dx.doi.org/10.1016/j.cancergencyto.2010.09.002DOI Listing
December 2010

Aging of Xenopus tropicalis eggs leads to deadenylation of a specific set of maternal mRNAs and loss of developmental potential.

PLoS One 2010 Oct 22;5(10):e13532. Epub 2010 Oct 22.

Institut für Zellbiologie (Tumorforschung), Universitätsklinikum Essen, Universität Duisburg-Essen, Essen, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013532PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962626PMC
October 2010

Synergistic effects of sonoporation and taurolidin/TRAIL on apoptosis in human fibrosarcoma.

Ultrasound Med Biol 2010 Nov 27;36(11):1893-906. Epub 2010 Sep 27.

Department of Hand, Plastic and Reconstructive Surgery, Burn Center, BG-Unfallkrankenhaus, Ludwigshafen, Germany.

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http://dx.doi.org/10.1016/j.ultrasmedbio.2010.08.009DOI Listing
November 2010

Widespread regulation of gene expression in the Drosophila genome by the histone acetyltransferase dTip60.

Chromosoma 2010 Feb 1;119(1):99-113. Epub 2009 Dec 1.

Abteilung für Genetik, Zentrum für Medizinische Biotechnologie, Universität Duisburg-Essen, Universitätsstrasse 5, 45117, Essen, Germany.

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http://dx.doi.org/10.1007/s00412-009-0247-zDOI Listing
February 2010

Functional signature of human islet-derived precursor cells compared to bone marrow-derived mesenchymal stem cells.

Stem Cells Dev 2010 May;19(5):679-91

Orthopedic Center for Musculoskeletal Research, Stem Cell Division, Orthopedic Department, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1089/scd.2009.0241DOI Listing
May 2010

Combined PER2 and CRY1 expression predicts outcome in chronic lymphocytic leukemia.

Eur J Haematol 2009 Oct 2;83(4):320-7. Epub 2009 Jun 2.

Department of Hematology, University Hospital, Hufelandstrasse 55, Essen, Germany.

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http://dx.doi.org/10.1111/j.1600-0609.2009.01287.xDOI Listing
October 2009

Malignant fibrous histiocytoma--pleomorphic sarcoma, NOS gene expression, histology, and clinical course. A pilot study.

Langenbecks Arch Surg 2010 Mar 22;395(3):261-75. Epub 2009 Jan 22.

Department of Plastic Surgery, Burn Center, Hand surgery, Sarcoma Reference Center, BG-University Hospital Bergmannsheil, Ruhr University Bochum, Bürkle-de-la-Camp-Platz 1, 44789, Bochum, Germany.

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http://dx.doi.org/10.1007/s00423-009-0465-0DOI Listing
March 2010

TRAIL and Taurolidine induce apoptosis and decrease proliferation in human fibrosarcoma.

J Exp Clin Cancer Res 2008 Dec 12;27:82. Epub 2008 Dec 12.

Department of Plastic Surgery, Burn Center, Hand Center, Sarcoma Reference Center, BG-University Hospital Bergmannsheil, Bürkle-de-la-Camp-Platz 1, 44789 Bochum, Germany.

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http://dx.doi.org/10.1186/1756-9966-27-82DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635882PMC
December 2008

Heterogeneous in vitro effects of doxorubicin on gene expression in primary human liposarcoma cultures.

BMC Cancer 2008 Oct 29;8:313. Epub 2008 Oct 29.

Department of Plastic Surgery, Burn Center, Hand surgery, Sarcoma Reference Center, BG-University Hospital Bergmannsheil, Ruhr University Bochum, Bürkle-de-la-Camp-Platz 1, 44789 Bochum, Germany.

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http://bmccancer.biomedcentral.com/articles/10.1186/1471-240
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http://dx.doi.org/10.1186/1471-2407-8-313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585096PMC
October 2008

Oral contraceptives prevent the development of endometriosis in the chicken chorioallantoic membrane model.

Contraception 2008 Sep 9;78(3):257-65. Epub 2008 Jul 9.

Department of Gynecology and Obstetrics, Maaslandziekenhuis, P.O. Box 5500, 6130 MB Sittard, The Netherlands.

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http://dx.doi.org/10.1016/j.contraception.2008.05.003DOI Listing
September 2008

Aberrant hypomethylation of the cancer-testis antigen PRAME correlates with PRAME expression in acute myeloid leukemia.

Ann Hematol 2008 Oct 28;87(10):809-18. Epub 2008 Jun 28.

Klinik für Hämatologie, Zentrum für Konservative Onkologie, Universitätsklinikum Essen, Hufelandstrasse 55, 45122, Essen, Germany.

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http://link.springer.com/10.1007/s00277-008-0514-8
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http://dx.doi.org/10.1007/s00277-008-0514-8DOI Listing
October 2008

Gene profiling of growth factor independence 1B gene (Gfi-1B) in leukemic cells.

Int J Hematol 2008 Jan 6;87(1):39-47. Epub 2007 Dec 6.

Department of Bone Marrow Transplantation, University Hospital of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1007/s12185-007-0013-zDOI Listing
January 2008

Identification of integrin-alpha4, Rb1, and syncytin a as murine placental target genes of the transcription factor GCMa/Gcm1.

J Biol Chem 2008 Feb 31;283(9):5460-5. Epub 2007 Dec 31.

Institut für Biochemie, Emil-Fischer-Zentrum, Universität Erlangen-Nürnberg, Fahrstr. 17, D-91054 Erlangen, Germany.

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http://dx.doi.org/10.1074/jbc.M710110200DOI Listing
February 2008

HNF4 alpha orchestrates a set of 14 genes to down-regulate cell proliferation in kidney cells.

Biol Chem 2008 Feb;389(2):179-87

Institut für Zellbiologie (Tumorforschung), Universitätsklinikum Essen, Universität Duisburg-Essen, D-45122 Essen, Germany.

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http://dx.doi.org/10.1515/BC.2008.011DOI Listing
February 2008

The first five years of the Wnt targetome.

Cell Signal 2008 May 17;20(5):795-802. Epub 2007 Nov 17.

Max-Planck-Institut für molekulare Physiologie, Otto-Hahn-Strasse 11, 44227, Dortmund, Germany.

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http://dx.doi.org/10.1016/j.cellsig.2007.10.031DOI Listing
May 2008

Differential impact of the transcriptional repressor Gfi1 on mature CD4+ and CD8+ T lymphocyte function.

Eur J Immunol 2007 Dec;37(12):3551-63

Institut für Zellbiologie (Tumorforschung), IFZ, Universitätsklinikum Essen, Essen, Germany.

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http://doi.wiley.com/10.1002/eji.200737130
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http://dx.doi.org/10.1002/eji.200737130DOI Listing
December 2007

Centrosomal CAP350 protein stabilises microtubules associated with the Golgi complex.

J Cell Sci 2007 Sep;120(Pt 18):3299-308

Institut Curie, Section Recherche, UMR144-CNRS, 75248 Paris CEDEX, France.

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http://dx.doi.org/10.1242/jcs.013102DOI Listing
September 2007

Microarray analyses of transdifferentiated mesenchymal stem cells.

J Cell Biochem 2008 Feb;103(2):413-33

University of Würzburg, Orthopedic Department, Orthopedic Center for Musculoskeletal Research, Würzburg, Germany.

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http://dx.doi.org/10.1002/jcb.21415DOI Listing
February 2008

Induction of inflammatory cytokines by a keratin mutation and their repression by a small molecule in a mouse model for EBS.

J Invest Dermatol 2007 Dec 21;127(12):2781-9. Epub 2007 Jun 21.

Institut für Physiologische Chemie, Abteilung für Zellbiochemie, Bonner Forum Biomedizin and LIMES, Rheinische Friedrich-Wilhelms-Universität, Nussallee 11, Bonn, Germany.

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http://dx.doi.org/10.1038/sj.jid.5700918DOI Listing
December 2007

Plasticity in adipogenesis and osteogenesis of human mesenchymal stem cells.

Mol Cell Endocrinol 2007 Jun 27;271(1-2):1-17. Epub 2007 Mar 27.

Orthopedic Center for Musculoskeletal Research, Orthopedic Department, University of Würzburg, Germany.

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http://dx.doi.org/10.1016/j.mce.2007.03.004DOI Listing
June 2007

Allelic loss in a minimal region on chromosome 16q24 is associated with vitreous seeding of retinoblastoma.

Cancer Res 2007 Jan;67(1):408-16

Institut für Humangenetik, Institut für Zellbiologie, and Augenklinik, Universitätsklinikum Essen, Hufelandstrasse 55, D-45122 Essen, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-1317DOI Listing
January 2007

Identification of target genes of the transcription factor HNF1beta and HNF1alpha in a human embryonic kidney cell line.

Biochim Biophys Acta 2005 Dec 2;1731(3):179-90. Epub 2005 Nov 2.

Institut für Zellbiologie (Tumorforschung), Universitätsklinikum Essen, D-45122 Essen, Germany.

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http://dx.doi.org/10.1016/j.bbaexp.2005.10.003DOI Listing
December 2005

Stringent regulation of DNA repair during human hematopoietic differentiation: a gene expression and functional analysis.

Stem Cells 2006 Mar 29;24(3):722-30. Epub 2005 Sep 29.

Institute of Cell Biology, University of Duisburg-Essen Medical School, Essen, Germany.

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http://doi.wiley.com/10.1634/stemcells.2005-0227
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http://dx.doi.org/10.1634/stemcells.2005-0227DOI Listing
March 2006

Prediction of clinical outcome and biological characterization of neuroblastoma by expression profiling.

Oncogene 2005 Nov;24(53):7902-12

Department of Pediatric Oncology and Hematology, University Hospital of Essen, Hufelandstr 55, Essen 45122, Germany.

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http://dx.doi.org/10.1038/sj.onc.1208936DOI Listing
November 2005

Functional analysis and secondary expression profiling of candidate genes deregulated in conjunction with oncogenic Ras signaling.

Adv Enzyme Regul 2005 15;45:63-84. Epub 2005 Jul 15.

Laboratory of Molecular Tumor Pathology, Charité, Universitätsmedizin Berlin, D-10117 Berlin, Germany.

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http://dx.doi.org/10.1016/j.advenzreg.2005.02.004DOI Listing
February 2006

HNF4alpha reduces proliferation of kidney cells and affects genes deregulated in renal cell carcinoma.

Oncogene 2005 Sep;24(42):6418-31

Institut für Zellbiologie (Tumorforschung), Universitätsklinikum Essen, D-45122 Essen, Germany.

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http://www.nature.com/articles/1208794
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http://dx.doi.org/10.1038/sj.onc.1208794DOI Listing
September 2005