Ludek Pour

Ludek Pour

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Ludek Pour

Ludek Pour

Publications by authors named "Ludek Pour"

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82Publications

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Circulating exosomal long noncoding RNA PRINS-First findings in monoclonal gammopathies.

Hematol Oncol 2018 Dec 13;36(5):786-791. Epub 2018 Sep 13.

Babak Myeloma Group, Department of Pathological Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.

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December 2018

Single agent daratumumab in advanced multiple myeloma possesses significant efficacy even in an unselected "real-world" population.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2018 Nov 6. Epub 2018 Nov 6.

Department of Haematooncology, University Hospital Ostrava and Faculty of Medicine, University of Ostrava, Czech Republic.

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November 2018

The impact of NF-κB signaling on pathogenesis and current treatment strategies in multiple myeloma.

Blood Rev 2018 Nov 23. Epub 2018 Nov 23.

Babak Myeloma Group, Department of Pathological Physiology, Masaryk University, Brno, Czech Republic. Electronic address:

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November 2018

Daratumumab plus Bortezomib, Melphalan, and Prednisone for Untreated Myeloma.

N Engl J Med 2018 02 12;378(6):518-528. Epub 2017 Dec 12.

From University Hospital of Salamanca-Instituto de Investigación Biomédica de Salamanca, Salamanca (M.-V.M.), and Clínica Universidad de Navarra-Centro de Investigación Médica Aplicada, Instituto de Investigación Sanitaria de Navarra, Centro de Investigación Biomédica en Red de Cáncer, Pamplona (J.S.-M.) - both in Spain; National and Kapodistrian University of Athens, Athens (M.A.D.); the Institute of Hematology, Department of Experimental, Diagnostic, and Specialty Medicine, University of Bologna, Bologna (M. Cavo), and Azienda Ospedaliera "Santa Maria," Terni (A.M.L.) - both in Italy; Japanese Red Cross Medical Center, Department of Hematology, Tokyo (K.S.); University of Chicago Medical Center, Chicago (A.J.); Würzburg University Medical Center, Würzburg, Germany (S.K.); Université Catholique de Louvain (UCL), Centre Hospitalier Universitaire UCL Namur, Yvoir (C.D.), and Janssen Research and Development, Beerse (W.D.) - both in Belgium; Champalimaud Center for the Unknown, Lisbon, Portugal (P.L.); Semmelweis Egyetem, Budapest, Hungary (Z.N.); Dnepropetrovsk City Clinical Hospital #4, Dnepropetrovsk, Ukraine (P.K.); University Hospital Brno, Brno, Czech Republic (L.P.); University Hospitals Birmingham NHS Foundation Trust, Birmingham (M. Cook), and Leicester Royal Infirmary-Haematology, Leicester (M.G.) - both in the United Kingdom; the Department of Cancer Prevention, School of Public Health, Silesian Medical University, Katowice, Poland (S.G.); Clínica de Tratamento E, Cuiaba, Brazil (A.C.); Andrew Love Cancer Centre, Geelong, VIC, Australia (P.C.); Clinic of Professional Pathology, Saratov, Russia (T.S.); the Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea (S.-S.Y.); LTD "Medinvent" Institute of Health, Tbilisi, Georgia (G.I.); Matsuyama Red Cross Hospital, Matsuyama, Japan (T.F.); Janssen Research and Development, Spring House, PA (C.C., R.C., W.C., M.Q.); and Janssen Research and Development, Raritan, NJ (J.W., H.N.).

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February 2018

Chromothripsis 18 in multiple myeloma patient with rapid extramedullary relapse.

Mol Cytogenet 2018 18;11. Epub 2018 Jan 18.

1Laboratory of Molecular Cytogenetics, Institute of Experimental Biology, Faculty of Science, Masaryk University, Kotlářská 2, 602 00 Brno, Czech Republic.

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January 2018

Deregulated expression of long non-coding RNA UCA1 in multiple myeloma.

Eur J Haematol 2017 Sep 29;99(3):223-233. Epub 2017 Jun 29.

Babak Myeloma Group, Department of Pathological Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.

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September 2017

Activity of aldehyde dehydrogenase in B-cell and plasma cell subsets of monoclonal gammopathy patients and healthy donors.

Eur J Haematol 2017 Jan 9;98(1):19-25. Epub 2016 Jun 9.

Department of Clinical Haematology, University Hospital Brno, Brno, Czech Republic.

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January 2017

Diffusion Tensor Imaging in Radiation-Induced Myelopathy.

J Neuroimaging 2015 Sep-Oct;25(5):836-40. Epub 2014 Dec 18.

University Hospital Brno and Masaryk University, Department of Radiology.

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November 2016

Cytogenetics in multiple myeloma patients progressing into extramedullary disease.

Eur J Haematol 2016 Jul 19;97(1):93-100. Epub 2015 Oct 19.

Babak Myeloma Group, Department of Pathological Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.

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July 2016

Circulating Serum MicroRNA-130a as a Novel Putative Marker of Extramedullary Myeloma.

PLoS One 2015 21;10(9):e0137294. Epub 2015 Sep 21.

Babak Myeloma Group, Department of Pathological Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic; Department of Clinical Hematology, University Hospital Brno, Brno, Czech Republic; Department of Hematooncology, Faculty of Medicine University of Ostrava and University Hospital Ostrava, Ostrava, Czech Republic.

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May 2016

Centrosome associated genes pattern for risk sub-stratification in multiple myeloma.

J Transl Med 2016 05 28;14(1):150. Epub 2016 May 28.

Department of Haematooncology, Faculty of Medicine, University of Ostrava, Dvořákova 7, 702 00, Ostrava, Czech Republic.

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May 2016

Oral Ixazomib, Lenalidomide, and Dexamethasone for Multiple Myeloma.

N Engl J Med 2016 Apr;374(17):1621-34

From University Hospital Hôtel Dieu, Nantes (P.M., C.T.), the Department of Hematology, Institut Paoli-Calmettes, Marseille (A.-M.S.), and the Department of Hematology and Cell Therapy, Hospital Saint Antoine, Paris (L.G.) - all in France; the Department of Haematology and Stem Cell Transplantation, St. István and St. László Hospital, 3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary (T.M.); the Department of Haemato-oncology and Bone Marrow Transplantation, Medical University of Lublin, and St. John's Cancer Center, Lublin, Poland (N.G.); Southern Alberta Cancer Research Institute, University of Calgary, Calgary (N.J.B.), and the Division of Hematology, Department of Medicine, University of Alberta, Edmonton (I.S.) - both in Canada; the Department of Hematology, Skåne University Hospital, Lund University, Lund, Sweden (M.H.); Hematology and Oncology, University Hospital Brno, Brno, Czech Republic (L.P.); the Department of Haematology, Christchurch Hospital, Christchurch (P. Ganly), the Department of Haematology, Palmerston North Hospital, Palmerston North, Manawatu (B.W.B.), the Department of Haematology, Middlemore Hospital, Auckland (S.R.J.), and the Department of Haematology, North Shore Hospital, Auckland (D.R.S.) - all in New Zealand; the Department of Hematology, University Hospital Rigshospitalet, Copenhagen (P. Gimsing); Myeloma Unit, Division of Hematology, University of Turin, Turin (A.P.), and Seràgnoli Institute of Haematology, Bologna University School of Medicine, St. Orsola-Malpighi University Hospital, Bologna (M.C.) - both in Italy; the Division of Hematology, Mayo Clinic, Rochester, MN (S.K., F.K.B.); and Dana-Farber Cancer Institute, Boston (J.P.L., P.G.R.), and Millennium Pharmaceuticals, Cambridge (D.T.B., J.L., A.D.B., A.-M.H., H.V.) - both in Massachusetts.

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April 2016

Multicentered patient-based evidence of the role of free light chain ratio normalization in multiple myeloma disease relapse.

Eur J Haematol 2016 Feb 21;96(2):119-27. Epub 2015 Apr 21.

4th Department of Medicine - Hematology, Charles University Hospital and Faculty of Medicine Hradec, Králové, Czech Republic.

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February 2016

Detection of tumor-specific marker for minimal residual disease in multiple myeloma patients.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2015 Dec 23;159(4):554-61. Epub 2014 Jun 23.

Babak Myeloma Group, Department of Pathological Physiology, Faculty of Medicine, Masaryk University Brno, Czech Republic.

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December 2015

Extramedullary relapse of multiple myeloma defined as the highest risk group based on deregulated gene expression data.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2015 Jun 16;159(2):288-93. Epub 2015 Apr 16.

Babak Myeloma Group, Department of Pathological Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.

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June 2015

Analysis of B-cell subpopulations in monoclonal gammopathies.

Clin Lymphoma Myeloma Leuk 2015 Apr 12;15(4):e61-71. Epub 2014 Dec 12.

Department of Clinical Haematology, University Hospital Brno, Brno, Czech Republic; Babak Myeloma Group, Department of Pathological Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic; Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic; Department of Haematooncology, University Hospital Ostrava, Ostrava, Czech Republic.

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April 2015

Combination of serum microRNA-320a and microRNA-320b as a marker for Waldenström macroglobulinemia.

Am J Hematol 2015 Mar 16;90(3):E51-2. Epub 2015 Jan 16.

Babak Myeloma Group, Department of Pathological Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic; Department of Clinical Hematology, University Hospital Brno, Brno, Czech Republic.

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March 2015

Proteasome inhibitors - molecular basis and current perspectives in multiple myeloma.

J Cell Mol Med 2014 Jun 8;18(6):947-61. Epub 2014 Apr 8.

Babak Myeloma Group, Department of Pathological Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic; Department of Clinical Hematology, University Hospital Brno, Brno, Czech Republic.

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June 2014

Cladribine (2-chlorodeoxyadenosine) in frontline chemotherapy for adult Langerhans cell histiocytosis: A single-center study of seven cases.

Acta Oncol 2013 Jun 31;52(5):994-1001. Epub 2012 Aug 31.

Department of Internal Medicine - Hematology and Oncology, Faculty of Medicine of Masaryk University and University Hospital Brno, Czech Republic.

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June 2013

Functionally suppressive CD8 T regulatory cells are increased in patients with multiple myeloma: a cause for immune impairment.

PLoS One 2012 13;7(11):e49446. Epub 2012 Nov 13.

Babak Myeloma Group, Department of Pathological Physiology, Faculty of Medicine, Masaryk University, Brno, Czech Republic.

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May 2013

Measuring diffuse metabolic activity on FDG-PET/CT: new method for evaluating Langerhans cell histiocytosis activity in pulmonary parenchyma.

Nucl Med Biol 2012 Apr 14;39(3):429-36. Epub 2011 Dec 14.

Department of Internal Medicine-Hematooncology, Faculty of Medicine of Masaryk University and University Hospital Brno, Czech Republic.

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April 2012

Similar efficacy of thalidomide- and bortezomib-based regimens for first relapse of multiple myeloma.

Ann Hematol 2011 Dec 5;90(12):1441-7. Epub 2011 Mar 5.

Department of Internal Medicine, Hematology and Oncology, University Hospital Brno, Jihlavska 20, 625 00, Brno, Czech Republic.

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December 2011

Multiple myeloma associated IgA pemphigus: treatment with bortezomib- and lenalidomide-based regimen.

Clin Lymphoma Myeloma Leuk 2011 Dec;11(6):517-20

Department of Internal Medicine - Hematooncology, Masaryk University and University Hospital Brno, Czech Republic.

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December 2011

Salvage treatment with upfront melphalan 100 mg/m(2) and consolidation with novel drugs for fulminant progression of multiple myeloma.

Ann Hematol 2010 May 19;89(5):483-7. Epub 2009 Nov 19.

Department of Internal Medicine-Hematooncology, Masaryk University Hospital, Jihlavska 20, Brno 62500, Czech Republic.

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May 2010

Levels of angiogenic factors in patients with multiple myeloma correlate with treatment response.

Ann Hematol 2010 Apr 26;89(4):385-9. Epub 2009 Sep 26.

Departement of Internal Medicine-Hematooncology, University Hospital Brno, Masaryk University, Brno, Czech Republic.

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April 2010

Epigenetics of multiple myeloma after treatment with cytostatics and gamma radiation.

Leuk Res 2009 Nov 10;33(11):1490-8. Epub 2009 Apr 10.

Institute of Biophysics, Academy of Sciences of the Czech Republic, 612 65 Brno, Czech Republic.

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November 2009

Varicella-zoster virus prophylaxis with low-dose acyclovir in patients with multiple myeloma treated with bortezomib.

Clin Lymphoma Myeloma 2009 Apr;9(2):151-3

Department of Internal Medicine-Hematooncology, University Hospital Brno, Masaryk University, Brno, Czech Republic.

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April 2009

Skin lesions induced by bortezomib.

Haematologica 2005 Dec;90(12 Suppl):ECR44

Department of Internal Medicine-Hematooncology , Masaryk University Hospital, Jihlavska 20, Brno, 625 00, Czech Republic.

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December 2005

Plasma concentrations of vascular endothelial growth factor and basic fibroblast growth factor in lymphoproliferative disorders.

Acta Medica (Hradec Kralove) 2005 ;48(1):57-8

Charles University in Prague, Faculty of Medicine in Hradec Králové, 2nd Department of Internal Medicine, Hradec Králové, Czech Republic.

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November 2005