Luda Diatchenko

Luda Diatchenko

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Luda Diatchenko

Luda Diatchenko

Publications by authors named "Luda Diatchenko"

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Premorbid and concurrent predictors of TMD onset and persistence.

Eur J Pain 2020 Jan 29;24(1):145-158. Epub 2019 Aug 29.

Pain Research and Intervention Center of Excellence, Gainesville, Florida.

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http://dx.doi.org/10.1002/ejp.1472DOI Listing
January 2020

NK cell recruitment limits tissue damage during an enteric helminth infection.

Mucosal Immunol 2019 Nov 27. Epub 2019 Nov 27.

Meakins-Christie Laboratories, Department of Medicine, McGill University Health Centre, Montreal, QC, H4A 3J1, Canada.

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http://dx.doi.org/10.1038/s41385-019-0231-8DOI Listing
November 2019

Stabilization of μ-opioid receptor facilitates its cellular translocation and signaling.

Proteins 2019 Oct 12;87(10):878-884. Epub 2019 Jun 12.

Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/prot.25751
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http://dx.doi.org/10.1002/prot.25751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718349PMC
October 2019

A study in scarlet: MC1R as the main predictor of red hair and exemplar of the flip-flop effect.

Hum Mol Genet 2019 06;28(12):2093-2106

Anesthesia and the Alan Edwards Centre for Research on Pain, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1093/hmg/ddz018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548228PMC
June 2019

Profound analgesia is associated with a truncated peptide resulting from tissue specific alternative splicing of DRG CA8-204 regulated by an exon-level cis-eQTL.

PLoS Genet 2019 06 14;15(6):e1008226. Epub 2019 Jun 14.

Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, Florida, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1008226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615631PMC
June 2019

Anatomical selectivity in overlap of chronic facial and bodily pain.

Pain Rep 2019 May-Jun;4(3):e729. Epub 2019 May 29.

Center for Pain Research and Innovation, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1097/PR9.0000000000000729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749913PMC
May 2019

Disentangling the genetics of lean mass.

Authors:
David Karasik M Carola Zillikens Yi-Hsiang Hsu Ali Aghdassi Kristina Akesson Najaf Amin Inês Barroso David A Bennett Lars Bertram Murielle Bochud Ingrid B Borecki Linda Broer Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos-Obando Jane A Cauley Peggy M Cawthon John C Chambers Zhao Chen Nam H Cho Hyung Jin Choi Wen-Chi Chou Steven R Cummings Lisette C P G M de Groot Phillip L De Jager Ilja Demuth Luda Diatchenko Michael J Econs Gudny Eiriksdottir Anke W Enneman Joel Eriksson Johan G Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Christian Gieger Harald Grallert Vilmundur Gudnason Launer J Lenore Caroline Hayward Albert Hofman Georg Homuth Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Toby Johnson Reiner Biffar Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Daniel L Koller Jaspal S Kooner William E Kraus Stephen Kritchevsky Zoltán Kutalik Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Markus M Lerch Joshua R Lewis Christina Lill Lars Lind Cecilia Lindgren Yongmei Liu Gregory Livshits Östen Ljunggren Ruth J F Loos Mattias Lorentzon Jian'an Luan Robert N Luben Ida Malkin Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Maria Nethander Anne B Newman Jeffery R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Munro Peacock Markus Perola Annette Peters Richard L Prince Bruce M Psaty Katri Räikkönen Stuart H Ralston Samuli Ripatti Fernando Rivadeneira John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Sabine Schipf Chan Soo Shin Albert V Smith Shad B Smith Nicole Soranzo Timothy D Spector Alena Stancáková Kari Stefansson Elisabeth Steinhagen-Thiessen Lisette Stolk Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Patricia Thompson Cynthia A Thomson Gudmar Thorleifsson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah André G Uitterlinden Cornelia M van Duijn Natasja M van Schoor Liesbeth Vandenput Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Nicholas J Wareham Dawn Waterworth Michael N Weedon H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Laura M Yerges-Armstrong Lei Yu Weihua Zhang Jing Hua Zhao Yanhua Zhou Carrie M Nielson Tamara B Harris Serkalem Demissie Douglas P Kiel Claes Ohlsson

Am J Clin Nutr 2019 02;109(2):276-287

Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1093/ajcn/nqy272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500901PMC
February 2019

Low back pain.

Nat Rev Dis Primers 2018 12 13;4(1):52. Epub 2018 Dec 13.

Center for Health and Medical Psychology, School of Law, Psychology, and Social Work, Örebro University, Örebro, Sweden.

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http://www.nature.com/articles/s41572-018-0052-1
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http://dx.doi.org/10.1038/s41572-018-0052-1DOI Listing
December 2018

The human pain genetics database: an interview with Luda Diatchenko.

Authors:
Luda Diatchenko

Pain Manag 2018 Jul 5;8(4):259-261. Epub 2018 Jun 5.

Alan Edwards Centre for Research on Pain; Department of Anesthesia, Faculty of Medicine; Faculty of Dentistry; McGill University; Genome Building, Room 2201740, Dr Penfield AvenueMontreal, Quebec, Canada H3A0G1.

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http://dx.doi.org/10.2217/pmt-2018-0028DOI Listing
July 2018

The more you test, the more you find: The smallest P-values become increasingly enriched with real findings as more tests are conducted.

Genet Epidemiol 2017 12 14;41(8):726-743. Epub 2017 Sep 14.

National Institute of Environmental Health Sciences, National Institutes of Health, Durham, North Carolina, USA.

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http://dx.doi.org/10.1002/gepi.22064DOI Listing
December 2017

Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Authors:
M Carola Zillikens Serkalem Demissie Yi-Hsiang Hsu Laura M Yerges-Armstrong Wen-Chi Chou Lisette Stolk Gregory Livshits Linda Broer Toby Johnson Daniel L Koller Zoltán Kutalik Jian'an Luan Ida Malkin Janina S Ried Albert V Smith Gudmar Thorleifsson Liesbeth Vandenput Jing Hua Zhao Weihua Zhang Ali Aghdassi Kristina Åkesson Najaf Amin Leslie J Baier Inês Barroso David A Bennett Lars Bertram Rainer Biffar Murielle Bochud Michael Boehnke Ingrid B Borecki Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos Obanda Jane A Cauley Peggy M Cawthon Henna Cederberg Zhao Chen Nam H Cho Hyung Jin Choi Melina Claussnitzer Francis Collins Steven R Cummings Philip L De Jager Ilja Demuth Rosalie A M Dhonukshe-Rutten Luda Diatchenko Gudny Eiriksdottir Anke W Enneman Mike Erdos Johan G Eriksson Joel Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Melissa Garcia Christian Gieger Thomas Girke Nicole L Glazer Harald Grallert Jagvir Grewal Bok-Ghee Han Robert L Hanson Caroline Hayward Albert Hofman Eric P Hoffman Georg Homuth Wen-Chi Hsueh Monica J Hubal Alan Hubbard Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Heikki A Koistinen William E Kraus Stephen Kritchevsky Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Lenore J Launer Jong-Young Lee Markus M Lerch Joshua R Lewis Lars Lind Cecilia Lindgren Yongmei Liu Tian Liu Youfang Liu Östen Ljunggren Mattias Lorentzon Robert N Luben William Maixner Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Simon Melov Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Anne Newman Carrie M Nielson Jeffrey R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Stephen C J Parker Munro Peacock Markus Perola Annette Peters Ozren Polasek Richard L Prince Katri Räikkönen Stuart H Ralston Samuli Ripatti John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Eric E Schadt Sabine Schipf Laura Scott Joban Sehmi Jian Shen Chan Soo Shin Gunnar Sigurdsson Shad Smith Nicole Soranzo Alena Stančáková Elisabeth Steinhagen-Thiessen Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Sian-Tsung Tan Mark A Tarnopolsky Patricia Thompson Cynthia A Thomson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah Jaakko Tuomilehto Natasja M van Schoor Arjun Verma Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Michael N Weedon Ryan Welch H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Weijia Xie Lei Yu Yanhua Zhou John C Chambers Angela Döring Cornelia M van Duijn Michael J Econs Vilmundur Gudnason Jaspal S Kooner Bruce M Psaty Timothy D Spector Kari Stefansson Fernando Rivadeneira André G Uitterlinden Nicholas J Wareham Vicky Ossowski Dawn Waterworth Ruth J F Loos David Karasik Tamara B Harris Claes Ohlsson Douglas P Kiel

Nat Commun 2017 11 7;8(1):1414. Epub 2017 Nov 7.

Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-01008-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676783PMC
November 2017

Car8 dorsal root ganglion expression and genetic regulation of analgesic responses are associated with a cis-eQTL in mice.

Mamm Genome 2017 Oct 25;28(9-10):407-415. Epub 2017 May 25.

Department of Pharmacology and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1007/s00335-017-9694-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5693610PMC
October 2017

T-Cell Mediation of Pregnancy Analgesia Affecting Chronic Pain in Mice.

J Neurosci 2017 10 6;37(41):9819-9827. Epub 2017 Sep 6.

Department of Psychology and Alan Edwards Centre for Research on Pain, McGill University, Montreal, Quebec H3A 1B1, Canada, and

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http://dx.doi.org/10.1523/JNEUROSCI.2053-17.2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596598PMC
October 2017

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass.

Authors:
M Carola Zillikens Serkalem Demissie Yi-Hsiang Hsu Laura M Yerges-Armstrong Wen-Chi Chou Lisette Stolk Gregory Livshits Linda Broer Toby Johnson Daniel L Koller Zoltán Kutalik Jian'an Luan Ida Malkin Janina S Ried Albert V Smith Gudmar Thorleifsson Liesbeth Vandenput Jing Hua Zhao Weihua Zhang Ali Aghdassi Kristina Åkesson Najaf Amin Leslie J Baier Inês Barroso David A Bennett Lars Bertram Rainer Biffar Murielle Bochud Michael Boehnke Ingrid B Borecki Aron S Buchman Liisa Byberg Harry Campbell Natalia Campos Obanda Jane A Cauley Peggy M Cawthon Henna Cederberg Zhao Chen Nam H Cho Hyung Jin Choi Melina Claussnitzer Francis Collins Steven R Cummings Philip L De Jager Ilja Demuth Rosalie A M Dhonukshe-Rutten Luda Diatchenko Gudny Eiriksdottir Anke W Enneman Mike Erdos Johan G Eriksson Joel Eriksson Karol Estrada Daniel S Evans Mary F Feitosa Mao Fu Melissa Garcia Christian Gieger Thomas Girke Nicole L Glazer Harald Grallert Jagvir Grewal Bok-Ghee Han Robert L Hanson Caroline Hayward Albert Hofman Eric P Hoffman Georg Homuth Wen-Chi Hsueh Monica J Hubal Alan Hubbard Kim M Huffman Lise B Husted Thomas Illig Erik Ingelsson Till Ittermann John-Olov Jansson Joanne M Jordan Antti Jula Magnus Karlsson Kay-Tee Khaw Tuomas O Kilpeläinen Norman Klopp Jacqueline S L Kloth Heikki A Koistinen William E Kraus Stephen Kritchevsky Teemu Kuulasmaa Johanna Kuusisto Markku Laakso Jari Lahti Thomas Lang Bente L Langdahl Lenore J Launer Jong-Young Lee Markus M Lerch Joshua R Lewis Lars Lind Cecilia Lindgren Yongmei Liu Tian Liu Youfang Liu Östen Ljunggren Mattias Lorentzon Robert N Luben William Maixner Fiona E McGuigan Carolina Medina-Gomez Thomas Meitinger Håkan Melhus Dan Mellström Simon Melov Karl Michaëlsson Braxton D Mitchell Andrew P Morris Leif Mosekilde Anne Newman Carrie M Nielson Jeffrey R O'Connell Ben A Oostra Eric S Orwoll Aarno Palotie Stephen C J Parker Munro Peacock Markus Perola Annette Peters Ozren Polasek Richard L Prince Katri Räikkönen Stuart H Ralston Samuli Ripatti John A Robbins Jerome I Rotter Igor Rudan Veikko Salomaa Suzanne Satterfield Eric E Schadt Sabine Schipf Laura Scott Joban Sehmi Jian Shen Chan Soo Shin Gunnar Sigurdsson Shad Smith Nicole Soranzo Alena Stančáková Elisabeth Steinhagen-Thiessen Elizabeth A Streeten Unnur Styrkarsdottir Karin M A Swart Sian-Tsung Tan Mark A Tarnopolsky Patricia Thompson Cynthia A Thomson Unnur Thorsteinsdottir Emmi Tikkanen Gregory J Tranah Jaakko Tuomilehto Natasja M van Schoor Arjun Verma Peter Vollenweider Henry Völzke Jean Wactawski-Wende Mark Walker Michael N Weedon Ryan Welch H-Erich Wichmann Elisabeth Widen Frances M K Williams James F Wilson Nicole C Wright Weijia Xie Lei Yu Yanhua Zhou John C Chambers Angela Döring Cornelia M van Duijn Michael J Econs Vilmundur Gudnason Jaspal S Kooner Bruce M Psaty Timothy D Spector Kari Stefansson Fernando Rivadeneira André G Uitterlinden Nicholas J Wareham Vicky Ossowski Dawn Waterworth Ruth J F Loos David Karasik Tamara B Harris Claes Ohlsson Douglas P Kiel

Nat Commun 2017 07 19;8(1):80. Epub 2017 Jul 19.

Hebrew SeniorLife, Institute for Aging Research, Roslindale, MA, 02131, USA.

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http://dx.doi.org/10.1038/s41467-017-00031-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5517526PMC
July 2017

N6-methyladenosine alters RNA structure to regulate binding of a low-complexity protein.

Nucleic Acids Res 2017 Jun;45(10):6051-6063

Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1093/nar/gkx141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449601PMC
June 2017

miR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes.

Science 2017 06 1;356(6343):1168-1171. Epub 2017 Jun 1.

Department of Medical Biochemistry and Biophysics, Division of Molecular Neurobiology, Karolinska Institutet, 17177 Stockholm, Sweden.

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http://dx.doi.org/10.1126/science.aam7671DOI Listing
June 2017

Genetic variant rs3750625 in the 3'UTR of ADRA2A affects stress-dependent acute pain severity after trauma and alters a microRNA-34a regulatory site.

Pain 2017 02;158(2):230-239

aTRYUMPH Research Program bDepartment of Anesthesiology, University of North Carolina, Chapel Hill, NC, USA cDepartment of Battlefield Pain Research, Fort Sam, TX, USAISR dForensic Nursing Program, Family Medicine, Cone Health System, Greensboro, NC, USA eDepartment of Emergency Medicine, William Beaumont Hospital, Royal Oak, MI, USA fDepartment of Emergency Medicine, Spectrum Health Butterworth Campus, Grand Rapids, MI, USA gThe Allan Edwards Centre for Research on Pain, McGill University, Montreal, QC, Canada hDepartment of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA iDepartment of Emergency Medicine, University of North Carolina, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1097/j.pain.0000000000000742DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239739PMC
February 2017

Agonist-dependence of functional properties for common nonsynonymous variants of human transient receptor potential vanilloid 1.

Pain 2016 07;157(7):1515-24

aThe Department of Neural and Pain Sciences, School of Dentistry, Program in Neuroscience, University of Maryland, Baltimore, MD, USA bAlan Edwards Centre for Research on Pain, McGill University, Montreal, QC, Canada.

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http://pdfs.journals.lww.com/pain/2016/07000/Agonist_depende
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http://dx.doi.org/10.1097/j.pain.0000000000000556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512168PMC
July 2016

Identification of clusters of individuals relevant to temporomandibular disorders and other chronic pain conditions: the OPPERA study.

Pain 2016 06;157(6):1266-78

aCenter for Pain Research and Innovation, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA Departments of bBiostatistics and cEndodontics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA dDepartment of Biostatistics, Harvard University, Boston, MA, USA Departments of eDental Ecology and fEpidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA gDepartment of Oral Diagnostic Sciences, University at Buffalo, Buffalo, NY, USA hPain Research and Intervention Center of Excellence, University of Florida, Gainesville, FL, USA iDepartment of Neural and Pain Sciences and Brotman Facial Pain Clinic, University of Maryland School of Dentistry, Baltimore, MD, USA jThe Alan Edwards Centre for Research on Pain, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.1097/j.pain.0000000000000518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949303PMC
June 2016

Human Genetic Variability Contributes to Postoperative Morphine Consumption.

J Pain 2016 05 21;17(5):628-36. Epub 2016 Feb 21.

SIMPAR (Study In Multidisciplinary Pain Research) Group, UO 2(a) Anestesia, Rianimazione e Terapia Antalgica, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy; Anesthesia, Critical Care and Pain Medicine, Department of Surgical Sciences, University of Parma, Parma, Italy; UO 2(a) Anestesia, Rianimazione e Terapia Antalgica, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jpain.2016.02.003DOI Listing
May 2016

Modification of COMT-dependent pain sensitivity by psychological stress and sex.

Pain 2016 Apr;157(4):858-67

aThe Alan Edwards Centre for Research on Pain, McGill University, McGill University Genome Building, Montreal, QC, Canada bDepartment of Anesthesiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA cCenter for Pain Research and Innovation, University of North Carolina at Chapel Hill; Department of Endodontics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA dDepartment of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA eCenter for Translational Pain Medicine, Duke University, Durham, NC, USA fDepartment of Neural and Pain Sciences, University of Maryland School of Dentistry, Baltimore, MD, USA; Brotman Facial Pain Center, University of Maryland School of Dentistry, Baltimore, MD, USA gCenter for Pain Research and Innovation, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Department of Dental Ecology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA hDepartment of Community Dentistry and Behavioral Science, University of Florida, College of Dentistry, and Pain, Research and Intervention Center of Excellence, Gainesville, FL, USA iDepartment of Oral Diagnostic Sciences, University at Buffalo, Buffalo, NY, USA.

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http://pdfs.journals.lww.com/pain/2016/04000/Modification_of
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/j.pain.0000000000000449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794347PMC
April 2016

N(6)-Methyladenosine Modification in a Long Noncoding RNA Hairpin Predisposes Its Conformation to Protein Binding.

J Mol Biol 2016 Feb 4;428(5 Pt A):822-833. Epub 2015 Sep 4.

Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637, USA; Institute of Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2015.08.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779075PMC
February 2016

Carbonic anhydrase-8 regulates inflammatory pain by inhibiting the ITPR1-cytosolic free calcium pathway.

PLoS One 2015 3;10(3):e0118273. Epub 2015 Mar 3.

Department of Anesthesiology, Perioperative Medicine and Pain Management, University of Miami Miller School of Medicine, Miami, Florida, United States of America; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, Florida, United States of America; John T Macdonald Foundation Department of Human Genetics, University of Miami Miller School of Medicine, Miami, Florida, United States of America; Bruce W. Carter Miami Veterans Healthcare System, Miami, Florida, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0118273PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347988PMC
January 2016

Dual allosteric modulation of opioid antinociceptive potency by α2A-adrenoceptors.

Neuropharmacology 2015 Dec 6;99:285-300. Epub 2015 Aug 6.

Alan Edwards Centre for Research on Pain, McGill University, Montreal, Quebec, Canada; Integrated Program in Neuroscience, McGill University, Montreal, Quebec, Canada; Faculty of Dentistry, McGill University, Montreal, Quebec, Canada; Department of Anesthesiology, Faculty of Medicine, McGill University, Montreal, Quebec, Canada; Department of Pharmacology & Therapeutics, Faculty of Medicine, McGill University, Montreal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2015.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655173PMC
December 2015

Genome-wide association meta-analyses to identify common genetic variants associated with hallux valgus in Caucasian and African Americans.

J Med Genet 2015 Nov 2;52(11):762-9. Epub 2015 Sep 2.

Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, North Carolina, USA Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, USA Department of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA Department of Orthopedics, University of North Carolina, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1136/jmedgenet-2015-103142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864963PMC
November 2015

Neuropathic pain phenotyping by international consensus (NeuroPPIC) for genetic studies: a NeuPSIG systematic review, Delphi survey, and expert panel recommendations.

Pain 2015 Nov;156(11):2337-53

aDivision of Population Health Sciences, University of Dundee, Dundee, Scotland, United Kingdom bBrain Function Research Group, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa cINSERM U-987, Centre d'Evaluation et de Traitement de la Douleur, CHU Ambroise Paré, Assistance Publique Hôpitaux de Paris, Boulogne-Billancourt, France dUniversité Versailles Saint-Quentin, Versailles, France eDivision of Neurological Pain Research and Therapy, Department of Neurology, Universitätsklinikum Schleswig-Holstein, Kiel, Germany fdeCODE Genetics/Amgen, Reykjavík, Iceland gNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom hAcademic Unit of Palliative Care, Leeds Institute of Health Sciences, University of Leeds, Leeds, United Kingdom iThe Alan Edwards Centre for Research on Pain, McGill University, Montreal, Canada jDepartment of Neurology, Beth Israel Deaconess Medical Centre, Harvard Medical School, Boston, USA kZentrum für Anästhesiologie, Intensivmedizin, Schmerztherapie und Palliativmedizin, Benedictus Krankenhaus, Tutzing, Germany lKlinik für Anästhesiologie, Technische Universität München, München, Germany mDepartment of Neurosurgery, Helsinki University Central Hospital, Helsinki, Finland nMutual Insurance Company Etera, Helsinki, Finland oDepartment of Clinical Medicine, Danish Pain Research Center, Aarhus University, Aarhus, Denmark pDepartment of Neurology, Aarhus University Hospital, Aarhus, Denmark qDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University, School of Medicine, Baltimore, USA rPain Research, Department of Surgery and Cancer, Faculty of Medicine, Imperial College, Chelsea and Westminster Hospital campus, London, United Kingdom sPain Phenomics and Genomics Lab, University of Toronto Centre for the Study of Pain, University of Toronto, Toronto, Canada tDepartment of Neurology, Technion Faculty of Medicine, Rambam Healt

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http://dx.doi.org/10.1097/j.pain.0000000000000335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747983PMC
November 2015

μ-Opioid receptor 6-transmembrane isoform: A potential therapeutic target for new effective opioids.

Prog Neuropsychopharmacol Biol Psychiatry 2015 Oct 6;62:61-7. Epub 2014 Dec 6.

The Alan Edwards Centre for Research on Pain, McGill University, 740 Dr. Penfield Avenue, Montreal, Quebec H3A 0G1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2014.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646084PMC
October 2015

Molecular genetic mechanisms of allelic specific regulation of murine Comt expression.

Pain 2015 Oct;156(10):1965-77

aCenter for Pain Research and Innovation, University of North Carolina, Chapel Hill, NC, USA bNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA cThe Alan Edwards Centre for Research on Pain, McGill University, Montreal, QC, Canada dDepartment of Oral Biology, School of Dentistry, University of North Carolina, Chapel Hill, NC, USA eDepartment of Psychiatry, University of North Carolina, Chapel Hill, NC, USA fPharmacotherapy and Experimental Therapeutics, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC, USA gDepartment of Psychology, McGill University, Montreal, QC, Canada hDepartment of Psychology, University of Toronto Mississauga, Mississauga, ON, Canada.

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http://dx.doi.org/10.1097/j.pain.0000000000000258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579042PMC
October 2015

COMT gene locus: new functional variants.

Pain 2015 Oct;156(10):2072-83

aThe Alan Edwards Centre for Research on Pain, McGill University, Montreal, QC, Canada bCenter for Pain Research and Innovation, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA cNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA dDepartment of Prosthesis and Periodontology, Piracicaba Dental School, State University of Campinas, Piracicaba, SP, Brazil eDepartment of Medicine, Division of Gastroenterology, College of Medicine, University of Florida, Gainesville, FL, USA fDepartment of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, NC, USA gDepartment of Community Dentistry and Behavioral Science, University of Florida, College of Dentistry, and Pain, Research and Intervention Center of Excellence, Clinical and Translational Research Building (CTRB), Gainesville, FL, USA hDepartment of Neural and Pain Sciences, and Brotman Facial Pain Clinic, University of Maryland School of Dentistry, Baltimore, MD, USA iDepartment of Oral Diagnostic Sciences, University at Buffalo, Buffalo, NY, USA jBattelle Memorial Institute, Battelle Centers for Public Health Research and Evaluation (CPHRE), Durham, NC, USA kNational Institute of Environmental Health Sciences, Durham, NC, USA lDivision of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.

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