Publications by authors named "Lucyna Konieczna"

38Publications

Plausible Role of Estrogens in Pathogenesis, Progression and Therapy of Lung Cancer.

Authors:
Claudia Musial Renata Zaucha Alicja Kuban-Jankowska Lucyna Konieczna Mariusz Belka Antonella Marino Gammazza Tomasz Baczek Francesco Cappello Michal Wozniak Magdalena Gorska-Ponikowska

Int J Environ Res Public Health 2021 Jan 14;18(2). Epub 2021 Jan 14.

Department of Medical Chemistry, Medical University of Gdansk, 80-211 Gdansk, Poland.

View Article and Find Full Text PDF
January 2021

Follicular fat-soluble vitamins as markers of oocyte competency.

Authors:
Patrycja Skowrońska Michał Kunicki Ewa Pastuszek Lucyna Konieczna Tomasz Bączek Krzysztof Łukaszuk

Syst Biol Reprod Med 2020 Apr 14;66(2):112-121. Epub 2020 Feb 14.

Department of Obstetrics and Gynecological Nursing, Faculty of Health Sciences, Medical University of Gdansk, Gdansk, Poland.

View Article and Find Full Text PDF
April 2020

Application of 3D-printed scabbard-like sorbent for sample preparation in bioanalysis expanded to 96-wellplate high-throughput format.

Authors:
Mariusz Belka Lucyna Konieczna Magdalena Okońska Magdalena Pyszka Szymon Ulenberg Tomasz Bączek

Anal Chim Acta 2019 Nov 4;1081:1-5. Epub 2019 Jun 4.

Department of Pharmaceutical Chemistry, Medical University of Gdańsk, Hallera 107, 80-416, Gdańsk, Poland.

View Article and Find Full Text PDF
November 2019

A targeted mass spectrometry immunoassay to quantify osteopontin in fresh-frozen breast tumors and adjacent normal breast tissues.

Authors:
Katarzyna Macur Lars Hagen Tomasz M Ciesielski Lucyna Konieczna Jarosław Skokowski Bjørn M Jenssen Geir Slupphaug Tomasz Bączek

J Proteomics 2019 09 30;208:103469. Epub 2019 Jul 30.

Department of Pharmaceutical Chemistry, Medical University of Gdańsk, al. Hallera 107, 80-416 Gdańsk, Poland. Electronic address:

View Article and Find Full Text PDF
September 2019

Aromatisation of steroids in the bivalve .

Authors:
Anna Hallmann Lucyna Konieczna Justyna Swiezak Ryszard Milczarek Katarzyna Smolarz

PeerJ 2019 22;7:e6953. Epub 2019 May 22.

Department of Marine Ecosystem Functioning, University of Gdańsk, Gdynia, Poland.

View Article and Find Full Text PDF
May 2019

Prevalence of chronic heart failure and asymptomatic left ventricular dysfunction in the general population: methods and preliminary results of the HF-Pomorskie Study.

Authors:
Aleksandra Puch-Walczak Piotr Hoffman Maria Dudziak Katarzyna Kunicka Łukasz Wierucki Ewa Puzio Krzysztof Kuziemski Magdalena Lipczyńska Lucyna Konieczna Tomasz Bączek Wojciech Drygas Tomasz Zdrojewski

Kardiol Pol 2018;76(11):1567-1569. Epub 2018 Oct 19.

Department of Preventive Medicine and Education, Medical University of Gdańsk, Gdańsk, Poland.

View Article and Find Full Text PDF
March 2019

Testosterone and dihydrotestosterone reduce platelet activation and reactivity in older men and women.

Authors:
Kamil Karolczak Lucyna Konieczna Tomasz Kostka Piotr J Witas Bartlomiej Soltysik Tomasz Baczek Cezary Watala

Aging (Albany NY) 2018 05;10(5):902-929

Department of Haemostatic Disorders, Medical University, Lodz, Poland.

View Article and Find Full Text PDF
May 2018

New 3D-printed sorbent for extraction of steroids from human plasma preceding LC-MS analysis.

Authors:
Lucyna Konieczna Mariusz Belka Magdalena Okońska Magdalena Pyszka Tomasz Bączek

J Chromatogr A 2018 Apr 21;1545:1-11. Epub 2018 Feb 21.

Department of Pharmaceutical Chemistry, Medical University of Gdańsk, al. gen. J. Hallera 107, 80-416 Gdańsk, Poland. Electronic address:

View Article and Find Full Text PDF
April 2018

Bioanalysis of underivatized amino acids in non-invasive exhaled breath condensate samples using liquid chromatography coupled with tandem mass spectrometry.

Authors:
Lucyna Konieczna Magdalena Pyszka Magdalena Okońska Maciej Niedźwiecki Tomasz Bączek

J Chromatogr A 2018 Mar 12;1542:72-81. Epub 2018 Feb 12.

Department of Pharmaceutical Chemistry, Medical University of Gdańsk, Gen. J. Hallera 107, 80-416 Gdańsk, Poland. Electronic address:

View Article and Find Full Text PDF
March 2018

A Proteomic-Based Approach to Study the Mechanism of Cytotoxicity Induced by Interleukin-1α and Cycloheximide.

Authors:
Katarzyna Macur Jolanta Grzenkowicz-Wydra Lucyna Konieczna Jacek Bigda Caterina Temporini Sara Tengattini Tomasz Bączek

Chromatographia 2018 30;81(1):47-56. Epub 2017 Aug 30.

3Department of Pharmaceutical Chemistry, Medical University of Gdańsk, al. Hallera 107, 80-416 Gdańsk, Poland.

View Article and Find Full Text PDF
August 2017

Bioanalysis of a panel of neurotransmitters and their metabolites in plasma samples obtained from pediatric patients with neuroblastoma and Wilms' tumor.

Authors:
Lucyna Konieczna Anna Roszkowska Teresa Stachowicz-Stencel Anna Synakiewicz Tomasz Bączek

J Chromatogr B Analyt Technol Biomed Life Sci 2018 Feb 28;1074-1075:99-110. Epub 2017 Dec 28.

Department of Pharmaceutical Chemistry, Medical University of Gdańsk, Hallera 107 Str., 80-416 Gdańsk, Poland. Electronic address:

View Article and Find Full Text PDF
February 2018

Changes in steroid profiles of the blue mussel Mytilus trossulus as a function of season, stage of gametogenesis, sex, tissue and mussel bed depth.

Authors:
Katarzyna Smolarz Sandra Zabrzańska Lucyna Konieczna Anna Hallmann

Gen Comp Endocrinol 2018 04 14;259:231-239. Epub 2017 Dec 14.

Department of Pharmaceutical Biochemistry, Medical University of Gdańsk, Poland. Electronic address:

View Article and Find Full Text PDF
April 2018

HILIC-MS Rat Brain Analysis, A New Approach for the Study of Ischemic Attack.

Authors:
Natalia Miękus Lucyna Konieczna Przemysław Kowiański Janusz Moryś Tomasz Bączek

Transl Neurosci 2017 12;8:70-75. Epub 2017 Aug 12.

Department of Pharmaceutical Chemistry, Medical University of Gdańsk, Gen. J. Hallera 107, 80-416Gdańsk, Poland.

View Article and Find Full Text PDF
August 2017

Amino acid profiles as potential biomarkers for pediatric cancers: a preliminary communication.

Authors:
Anna Synakiewicz Malgorzata Sawicka-Zukowska Natalia Adrianowska Grazyna Galezowska Joanna Ratajczyk Anna Owczarzak Lucyna Konieczna Teresa Stachowicz-Stencel

Biomark Med 2017 Aug 3;11(8):619-627. Epub 2017 Aug 3.

Department of Pediatrics, Hematology and Oncology, Medical University of Gdansk, 80-211 Gdansk, Poland.

View Article and Find Full Text PDF
August 2017

A Novel Two-Step Liquid-Liquid Extraction Procedure Combined with Stationary Phase Immobilized Human Serum Albumin for the Chiral Separation of Cetirizine Enantiomers along with M and P Parabens.

Authors:
Aleksandra Chmielewska Lucyna Konieczna Tomasz Bączek

Molecules 2016 Dec 7;21(12). Epub 2016 Dec 7.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, Hallera 107, PL-80-416 Gdańsk, Poland.

View Article and Find Full Text PDF
December 2016

The LC-MS method for the simultaneous analysis of selected fat-soluble vitamins and their metabolites in serum samples obtained from pediatric patients with cystic fibrosis.

Authors:
Lucyna Konieczna Katarzyna Kaźmierska Anna Roszkowska Agnieszka Szlagatys-Sidorkiewicz Tomasz Bączek

J Pharm Biomed Anal 2016 May 15;124:374-381. Epub 2016 Mar 15.

Department of Pharmaceutical Chemistry, Medical University of Gdańsk, Hallera 107, 80-416 Gdańsk, Poland. Electronic address:

View Article and Find Full Text PDF
May 2016

Analytical approach to determining human biogenic amines and their metabolites using eVol microextraction in packed syringe coupled to liquid chromatography mass spectrometry method with hydrophilic interaction chromatography column.

Authors:
Lucyna Konieczna Anna Roszkowska Anna Synakiewicz Teresa Stachowicz-Stencel Elżbieta Adamkiewicz-Drożyńska Tomasz Bączek

Talanta 2016 Apr 21;150:331-9. Epub 2015 Dec 21.

Department of Pharmaceutical Chemistry, Medical University of Gdańsk, Gen. J. Hallera 107, Gdańsk, Poland. Electronic address:

View Article and Find Full Text PDF
April 2016

Hydrophilic interaction chromatography combined with dispersive liquid-liquid microextraction as a preconcentration tool for the simultaneous determination of the panel of underivatized neurotransmitters in human urine samples.

Authors:
Lucyna Konieczna Anna Roszkowska Maciej Niedźwiecki Tomasz Bączek

J Chromatogr A 2016 Jan 23;1431:111-121. Epub 2015 Dec 23.

Department of Pharmaceutical Chemistry, Medical University of Gdańsk, Gen. J. Hallera 107, 80-416 Gdańsk, Poland. Electronic address:

View Article and Find Full Text PDF
January 2016

LC-MS measurment of free steroids in mussels (Mytilus trossulus) from the southern Baltic Sea.

Authors:
Anna Hallmann Katarzyna Smolarz Lucyna Konieczna Sandra Zabrzańska Mariusz Belka Tomasz Bączek

J Pharm Biomed Anal 2016 Jan 15;117:311-5. Epub 2015 Sep 15.

Department of Pharmaceutical Chemistry, Medical University of Gdańsk, Poland.

View Article and Find Full Text PDF
January 2016

Sex-related differences in steroid concentrations in the blue mussel (Mytilus edulis trossulus) from the southern Baltic Sea.

Authors:
Sandra Zabrzańska Katarzyna Smolarz Anna Hallmann Lucyna Konieczna Tomasz Bączek Maciej Wołowicz

Comp Biochem Physiol A Mol Integr Physiol 2015 May 20;183:14-9. Epub 2014 Dec 20.

Department of Marine Ecosystems' Functioning, Institute of Oceanography, University of Gdańsk, Al. Marszałka Piłsudskiego 46, Gdynia 81-378, Poland.

View Article and Find Full Text PDF
May 2015

Development of the HPLC Method for Simultaneous Determination of Lidocaine Hydrochloride and Tribenoside Along with Their Impurities Supported by the QSRR Approach.

Authors:
Alina Plenis Lucyna Konieczna Natalia Miękus Tomasz Bączek

Chromatographia 2013 Mar 1;76(5-6):255-265. Epub 2012 Nov 1.

Department of Pharmaceutical Chemistry, Medical University of Gdańsk, Hallera 107, 80-416 Gdańsk, Poland.

View Article and Find Full Text PDF
March 2013

Advanced assessment of the endogenous hormone level as a potential biomarker of the urogenital tract cancer.

Authors:
Lucyna Konieczna Mariusz Belka Tomasz Baczek Mateusz Ruszkowski Wiktoria Struck Michał Markuszewski Roman Kaliszan Marcin Markuszewski

Comb Chem High Throughput Screen 2013 Jul;16(6):463-72

Department of Pharmaceutical Chemistry, Medical University of Gdansk, 80-416 Gdańsk, Poland.

View Article and Find Full Text PDF
July 2013

The osteopontin tissue level as a breast cancer biomarker in females after mastectomy measured by the capillary gel electrophoresis technique.

Authors:
Lucyna Konieczna Jaroslaw Skokowski Ilona Oledzka Katarzyna Macur Mariusz Belka Tomasz Baczek Wiktoria Struck Michał Markuszewski

Comb Chem High Throughput Screen 2013 Jun;16(5):331-8

Department of Pharmaceutical Chemistry, Medical University of Gdańsk, Gdańsk, Poland.

View Article and Find Full Text PDF
June 2013

Antitumor activity of novel benzensulfonamide derivatives in view of their physiochemical properties searched by principal component analysis.

Authors:
Mariusz Belka Jarosław Sławinski Lucyna Konieczna Piotr Kawczak Tomasz Ciesielski Tomasz Baczek

Med Chem 2013 Jun;9(4):517-25

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, Gdańsk, Poland.

View Article and Find Full Text PDF
June 2013

Chemometric exploration of the dependencies between molecular modeling descriptors and analytical chemistry data of antihistaminic drugs.

Authors:
Lucyna Konieczna Leszek Bober Mariusz Belka Tomiasz Ciesielski Tomasz Baczeki

J AOAC Int 2012 May-Jun;95(3):713-23

Medical University of Gdansk, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Gdansk, Poland.

View Article and Find Full Text PDF
August 2012

Topotecan exposure estimation in pediatric acute myeloid leukemia supported by LC-MS-based drug monitoring and pharmacokinetic analysis.

Authors:
Tomasz Bączek Lucyna Konieczna Mariusz Belka Lucyna Maciejka-Kapuścińska Jakub Wiśniewski Maciej Niedźwiecki Anna Balcerska Elżbieta Adamkiewicz-Drożyńska Jacek Wachowiak

J Pharm Biomed Anal 2012 Nov 15;70:330-6. Epub 2012 May 15.

Department of Pharmaceutical Chemistry, Medical University of Gdańsk, Gen. J. Hallera 107, 80-416 Gdańsk, Poland.

View Article and Find Full Text PDF
November 2012

Biomedical evaluation of cortisol, cortisone, and corticosterone along with testosterone and epitestosterone applying micellar electrokinetic chromatography.

Authors:
Tomasz Bączek Ilona Olędzka Lucyna Konieczna Piotr Kowalski Alina Plenis

ScientificWorldJournal 2012 12;2012:268120. Epub 2012 Mar 12.

Department of Pharmaceutical Chemistry, Medical University of Gdańsk, Hallera 107, 80-416 Gdańsk, Poland.

View Article and Find Full Text PDF
July 2012

Steroid profiles as potential biomarkers in patients with urogenital tract cancer for diagnostic investigations analyzed by liquid chromatography coupled to mass spectrometry.

Authors:
Lucyna Konieczna Tomasz Bączek Mariusz Belka Anna Fel Marcin Markuszewski Wiktoria Struck Michał Markuszewski Roman Kaliszan

J Pharm Biomed Anal 2013 Jan 16;73:108-15. Epub 2012 Mar 16.

Department of Pharmaceutical Chemistry, Medical University of Gdańsk, Gen. J. Hallera 107, 80-416 Gdańsk, Poland.

View Article and Find Full Text PDF
January 2013

Simultaneous determination of urinary cortisol, cortisone and corticosterone in parachutists, depressed patients and healthy controls in view of biomedical and pharmacokinetic studies.

Authors:
Alina Plenis Lucyna Konieczna Ilona Olędzka Piotr Kowalski Tomasz Bączek

Mol Biosyst 2011 May 21;7(5):1487-500. Epub 2011 Feb 21.

Department of Pharmaceutical Chemistry, Medical University of Gdańsk, Hallera 107, 80-416 Gdańsk, Poland.

View Article and Find Full Text PDF
May 2011

Optimization of LC method for the determination of testosterone and epitestosterone in urine samples in view of biomedical studies and anti-doping research studies.

Authors:
Lucyna Konieczna Alina Plenis Ilona Olędzka Piotr Kowalski Tomasz Bączek

Talanta 2011 Jan 4;83(3):804-14. Epub 2010 Nov 4.

Department of Pharmaceutical Chemistry, Medical University of Gdańsk, Hallera 107, 80-416, Gdańsk, Poland.

View Article and Find Full Text PDF
January 2011

Optimization and validation of the micellar electrokinetic capillary chromatographic method for simultaneous determination of sulfonamide and amphenicol-type drugs in poultry tissue.

Authors:
Piotr Kowalski Alina Plenis Ilona Oledzka Lucyna Konieczna

J Pharm Biomed Anal 2011 Jan 17;54(1):160-7. Epub 2010 Aug 17.

Medical University of Gdańsk, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Hallera 107, PL 80-416 Gdańsk, Poland.

View Article and Find Full Text PDF
January 2011

Micellar electrokinetic chromatography for the determination of cortisol in urine samples in view of biomedical studies.

Authors:
Ilona Oledzka Alina Plenis Lucyna Konieczna Piotr Kowalski Tomasz Baczek

Electrophoresis 2010 Jul;31(14):2356-64

Department of Pharmaceutical Chemistry, Medical University of Gdańsk, Gdańsk, Poland.

View Article and Find Full Text PDF
July 2010

A validated high-performance liquid chromatographic method for the determination of moclobemide and its two metabolites in human plasma and application to pharmacokinetic studies.

Authors:
Alina Plenis Aleksandra Chmielewska Lucyna Konieczna Henryk Lamparczyk

Biomed Chromatogr 2007 Sep;21(9):958-66

Medical University of Gdańsk, Faculty of Pharmacy, Hallera 107, PL-80-416 Gdańsk, Poland.

View Article and Find Full Text PDF
September 2007

Sensitive quantification of chosen drugs by reversed-phase chromatography with electrochemical detection at a glassy carbon electrode.

Authors:
Aleksandra Chmielewska Lucyna Konieczna Alina Plenis Henryk Lamparczyk

J Chromatogr B Analyt Technol Biomed Life Sci 2006 Jul 22;839(1-2):102-11. Epub 2006 May 22.

Medical University of Gdańsk, Faculty of Pharmacy, Hallera 107, PL-80-416 Gdańsk, Poland.

View Article and Find Full Text PDF
July 2006

Influence of sex on the pharmacokinetics of ciprofloxacin and ofloxacin.

Authors:
Lucyna Konieczna Aleksandra Chmielewska Henryk Lamparczyk

Chemotherapy 2006 4;52(3):111-21. Epub 2006 Apr 4.

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Medical University of Gdańsk, Poland.

View Article and Find Full Text PDF
June 2006

Comparative evaluation between capillary electrophoresis and high-performance liquid chromatography for the analysis of florfenicol in plasma.

Authors:
Piotr Kowalski Lucyna Konieczna Aleksandra Chmielewska Ilona Oledzka Alina Plenis Michał Bieniecki Henryk Lamparczyk

J Pharm Biomed Anal 2005 Oct 3;39(5):983-9. Epub 2005 Aug 3.

Medical University of Gdańsk, Faculty of Pharmacy, Hallera 107, PL-80-416 Gdańsk, Poland.

View Article and Find Full Text PDF
October 2005

Determination of diclofenac in plasma by high-performance liquid chromatography with electrochemical detection.

Authors:
Aleksandra Chmielewska Lucyna Konieczna Alina Plenis Michał Bieniecki Henryk Lamparczyk

Biomed Chromatogr 2006 Jan;20(1):119-24

Medical University of Gdańsk, Faculty of Pharmacy, Hallera 107, PL-80-416 Gdańsk, Poland.

View Article and Find Full Text PDF
January 2006

The bioequivalence study of baclofen and lioresal tablets using capillary electrophoresis.

Authors:
Piotr Kowalski Aleksandra Chmielewska Lucyna Konieczna Ilona Oledzka Paweł K Zarzycki Henryk Lamparczyk

Biomed Chromatogr 2004 Jun;18(5):311-7

Medical University of Gdańsk, Faculty of Pharmacy, Hallera 107, PL-80-416 Gdańsk, Poland.

View Article and Find Full Text PDF
June 2004