Lucy C Chappell

Lucy C Chappell

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Lucy C Chappell

Lucy C Chappell

Publications by authors named "Lucy C Chappell"

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Combined diffusion-relaxometry MRI to identify dysfunction in the human placenta.

Magn Reson Med 2019 Jul 18;82(1):95-106. Epub 2019 Mar 18.

Centre for Medical Image Computing and Department of Computer Science, University College London, London, United Kingdom.

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http://dx.doi.org/10.1002/mrm.27733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519240PMC
July 2019

Placental growth factor testing to assess women with suspected pre-eclampsia: a multicentre, pragmatic, stepped-wedge cluster-randomised controlled trial.

Lancet 2019 05 1;393(10183):1807-1818. Epub 2019 Apr 1.

Department of Women and Children's Health, School of Life Course Sciences, King's College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(18)33212-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497988PMC
May 2019

Markers of maternal cardiac dysfunction in pre-eclampsia and superimposed pre-eclampsia.

Eur J Obstet Gynecol Reprod Biol 2019 Apr 19;237:151-156. Epub 2019 Apr 19.

Department of Women and Children's Health, School of Life Course Sciences, King's College London, London, UK; The Irish Centre for Fetal and Neonatal Translational Research, University College Cork, Wilton, Ireland Cork, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.ejogrb.2019.04.034DOI Listing
April 2019

Serum Creatinine in Pregnancy: A Systematic Review.

Kidney Int Rep 2019 Mar 29;4(3):408-419. Epub 2018 Oct 29.

Department of Women and Children's Health, King's College London, London, UK.

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http://dx.doi.org/10.1016/j.ekir.2018.10.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409397PMC
March 2019

Incidence of eclampsia and related complications across 10 low- and middle-resource geographical regions: Secondary analysis of a cluster randomised controlled trial.

PLoS Med 2019 Mar 29;16(3):e1002775. Epub 2019 Mar 29.

Department of Women and Children's Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1002775DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440614PMC
March 2019

Multi-modal functional MRI to explore placental function over gestation.

Magn Reson Med 2019 02 21;81(2):1191-1204. Epub 2018 Sep 21.

Centre for the Developing Brain, King's College London, United Kingdom.

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http://dx.doi.org/10.1002/mrm.27447DOI Listing
February 2019

Reducing maternal deaths from hypertensive disorders: learning from confidential inquiries.

BMJ 2019 Feb 5;364:l230. Epub 2019 Feb 5.

Department of Women and Children's Health, School of Life Course Sciences, King's College London, London, UK

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http://dx.doi.org/10.1136/bmj.l230DOI Listing
February 2019

Placental Growth Factor informed management of suspected pre-eclampsia or fetal growth restriction: The MAPPLE cohort study.

Pregnancy Hypertens 2018 Oct 26;14:228-233. Epub 2018 Mar 26.

Department of Women's and Children's Health Research, University of Liverpool, United Kingdom.

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http://dx.doi.org/10.1016/j.preghy.2018.03.013DOI Listing
October 2018

The impact of ethnicity on adverse perinatal outcome in women with chronic hypertension: a cohort study.

Ultrasound Obstet Gynecol 2018 Oct 14. Epub 2018 Oct 14.

Division of Women's Health, King's College London 10th floor North Wing, St Thomas' Hospital, London, UK, SE1 7EH.

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http://dx.doi.org/10.1002/uog.20132DOI Listing
October 2018

Prospective biomarkers in preterm preeclampsia: A review.

Pregnancy Hypertens 2018 Oct 23;14:72-78. Epub 2018 Mar 23.

NIHR Research Professor in Obstetrics, King's College London. Honorary Consultant Obstetrician, St Thomas' Hospital, London SE1 7EH, UK.

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http://dx.doi.org/10.1016/j.preghy.2018.03.010DOI Listing
October 2018

What is the evidence for using labetalol as a first-line treatment option for hypertension in pregnancy?

Drug Ther Bull 2018 09 27;56(9):107-111. Epub 2018 Aug 27.

Department of Women and Children's Health, King's College London, 10th Floor North Wing, St Thomas' Hospital, London, UK.

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http://dx.doi.org/10.1136/dtb.2018.9.000008DOI Listing
September 2018

Why is the search for pre-eclampsia prevention so elusive?

BMJ 2018 09 12;362:k3536. Epub 2018 Sep 12.

School of Life Course Sciences, King's College London, UK

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http://dx.doi.org/10.1136/bmj.k3536DOI Listing
September 2018

Prediction of pre-eclampsia: review of reviews.

Ultrasound Obstet Gynecol 2018 Sep 28. Epub 2018 Sep 28.

Women's Health Research Unit, Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1002/uog.20117DOI Listing
September 2018

Chronic hypertension in pregnancy: impact of ethnicity and superimposed preeclampsia on placental, endothelial, and renal biomarkers.

Am J Physiol Regul Integr Comp Physiol 2018 Jul 7;315(1):R36-R47. Epub 2018 Mar 7.

Women's Health Academic Centre, King's College London, St. Thomas' Hospital , London , United Kingdom.

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http://dx.doi.org/10.1152/ajpregu.00139.2017DOI Listing
July 2018

Early warning system hypertension thresholds to predict adverse outcomes in pre-eclampsia: A prospective cohort study.

Pregnancy Hypertens 2018 Apr 21;12:183-188. Epub 2017 Nov 21.

Women's Health Academic Centre, 10th Floor, North Wing, St Thomas' Hospital, Westminster Bridge Road, King's College London, London SE1 7EH, UK. Electronic address:

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http://dx.doi.org/10.1016/j.preghy.2017.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008490PMC
April 2018

Reduced fetal movements.

BMJ 2018 03 6;360:k570. Epub 2018 Mar 6.

King's College London, St Thomas' Hospital, London.

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http://dx.doi.org/10.1136/bmj.k570DOI Listing
March 2018

Does ursodeoxycholic acid improve perinatal outcomes in women with intrahepatic cholestasis of pregnancy?

BMJ 2018 02 1;360:k104. Epub 2018 Feb 1.

Women's Health Academic Centre, King's College London, London, UK.

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http://dx.doi.org/10.1136/bmj.k104DOI Listing
February 2018

Labetalol Versus Nifedipine as Antihypertensive Treatment for Chronic Hypertension in Pregnancy: A Randomized Controlled Trial.

Hypertension 2017 11 11;70(5):915-922. Epub 2017 Sep 11.

From the Women's Health Academic Centre, King's College London, United Kingdom (L.M.W., C.N.-P., P.T.S., L.C.C.); Directorate of Women's Health, Guy's and St Thomas' Foundation Trust, London, United Kingdom (L.M.W., C.N.-P., K.H., L.C.C.); Maternaland Fetal Health ResearchCenter, Division of Developmental Biology and Medicine, School of Medical Sciences, University of Manchester, Manchester Academic Health ScienceCenter, UnitedKingdom(J.E.M.); St Mary's Hospital, Central Manchester Foundation Trust, United Kingdom (J.E.M.); Cardiovascular Division, Department of Clinical Pharmacology, St Thomas' Hospital, King's College London British Heart Foundation Centre, United Kingdom (J.K.C.); Fetal Maternal Medicine Unit, St George's University of London,UnitedKingdom (I.W.-C., A.K.); andDepartment of Obstetrics and Gynaecology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, United Kingdom (C.W.).

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https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.117.
Publisher Site
http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09972DOI Listing
November 2017

Preterm pre-eclampsia: What every neonatologist should know.

Early Hum Dev 2017 11 13;114:26-30. Epub 2017 Sep 13.

Department of Women and Children's Health, Faculty of Life Sciences and Medicine, King's College London, London SE1 7EH, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.earlhumdev.2017.09.010DOI Listing
November 2017

Maternal deaths in the UK: pre-eclampsia deaths are avoidable.

Lancet 2017 02;389(10069):582-584

Women's Health Academic Centre, King's College London, London SE1 7EH, UK.

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http://dx.doi.org/10.1016/S0140-6736(17)30184-8DOI Listing
February 2017

Improving the Pipeline for Developing and Testing Pharmacological Treatments in Pregnancy.

PLoS Med 2016 Nov 1;13(11):e1002161. Epub 2016 Nov 1.

Institute for Women's Health, University College London, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1002161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089678PMC
November 2016

Urinary congophilia in women with hypertensive disorders of pregnancy and preexisting proteinuria or hypertension.

Am J Obstet Gynecol 2016 10 29;215(4):464.e1-7. Epub 2016 Apr 29.

Women's Health Academic Centre King's College London, St Thomas' Hospital, London, United Kingdom.

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http://dx.doi.org/10.1016/j.ajog.2016.04.041DOI Listing
October 2016

Pregnancy outcomes in myeloproliferative neoplasms: UK prospective cohort study.

Br J Haematol 2016 Oct 9;175(1):31-6. Epub 2016 Sep 9.

Department of Haematology, Guy's and St. Thomas' NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1111/bjh.14289DOI Listing
October 2016

Oxidative stress in pregnancy and reproduction.

Obstet Med 2016 Sep 17;9(3):113-6. Epub 2016 May 17.

Women's Health Academic Centre, King's College London, London, UK.

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http://dx.doi.org/10.1177/1753495X16648495DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010123PMC
September 2016

Diagnostic Biomarkers in Women With Suspected Preeclampsia in a Prospective Multicenter Study.

Obstet Gynecol 2016 08;128(2):245-52

Women's Health Academic Centre, King's College London, London, the Maternal and Fetal Health Research Centre, University of Manchester, Manchester, Nuffield Department of Obstetrics and Gynaecology, University of Oxford, and Oxford University Hospital NHS Trust, Oxford, the Division of Women's and Children's Health, University of Leeds, Leeds, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, and the Academic Unit of Reproductive and Developmental Medicine, University of Sheffield, Sheffield, United Kingdom; and INFANT Irish Centre for Fetal and Neonatal Translational Research, University College Cork, Cork, Ireland.

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http://dx.doi.org/10.1097/AOG.0000000000001508DOI Listing
August 2016

Placental growth factor as a marker of fetal growth restriction caused by placental dysfunction.

Placenta 2016 06 23;42:1-8. Epub 2016 Mar 23.

Department of Obstetrics and Gynaecology, Faculty of Medicine, University of British Columbia, 4500 Oak Street, Vancouver, British Columbia, V6H 3N1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.placenta.2016.03.010DOI Listing
June 2016

Management of a new pregnancy in a woman with chronic hypertension.

BMJ 2016 06 6;353:i1497. Epub 2016 Jun 6.

Women's Health Academic Centre, King's College London, London, UK.

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http://dx.doi.org/10.1136/bmj.i1497DOI Listing
June 2016

Diagnostic and predictive biomarkers for pre-eclampsia in patients with established hypertension and chronic kidney disease.

Kidney Int 2016 Apr 19;89(4):874-85. Epub 2016 Jan 19.

Division of Women's Health, Women's Health Academic Centre, King's College London and King's Health Partners, St. Thomas' Hospital, London, UK.

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http://dx.doi.org/10.1016/j.kint.2015.10.012DOI Listing
April 2016

Learning about maternal death and grief in the profession: a pilot qualitative study.

Acta Obstet Gynecol Scand 2015 Dec 4;94(12):1346-53. Epub 2015 Oct 4.

Women's Health Academic Centre, King's College London, London, UK.

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http://dx.doi.org/10.1111/aogs.12760DOI Listing
December 2015

Predicting pre-eclampsia.

BMJ 2015 Nov 25;351:h6349. Epub 2015 Nov 25.

Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford OX2 6GG, UK.

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http://dx.doi.org/10.1136/bmj.h6349DOI Listing
November 2015

Accuracy validation of the Microlife 3AS1-2 blood pressure device in a pregnant population with low blood pressure.

Blood Press Monit 2015 Oct;20(5):299-302

Women's Health Academic Centre, King's College London, St Thomas' Hospital, London, UK.

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https://insights.ovid.com/crossref?an=00126097-201510000-000
Publisher Site
http://dx.doi.org/10.1097/MBP.0000000000000134DOI Listing
October 2015

Adverse maternal and perinatal outcomes in pregnant women with sickle cell disease: systematic review and meta-analysis.

Blood 2015 May 23;125(21):3316-25. Epub 2015 Mar 23.

Women's Health Academic Centre, King's College London, London, United Kingdom; Women's Services, Guy's and St. Thomas' NHS Foundation Trust, London, United Kingdom;

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http://dx.doi.org/10.1182/blood-2014-11-607317DOI Listing
May 2015

Is early induction or expectant management more beneficial in women with late preterm pre-eclampsia?

BMJ 2015 Apr 10;350:h191. Epub 2015 Apr 10.

Women's Health Academic Centre, King's College London, London SE1 7EH, UK.

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http://dx.doi.org/10.1136/bmj.h191DOI Listing
April 2015

Exploration and confirmation of factors associated with uncomplicated pregnancy in nulliparous women: prospective cohort study.

Br J Sports Med 2015 Jan;49(2):136

Division of Women's Health, Women's Health Academic Centre, King's College London and King's Health Partners, UK.

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http://dx.doi.org/10.1136/bjsports-2014-f6398repDOI Listing
January 2015

Short-term prediction of preeclampsia: how close are we?

Biomark Med 2014 ;8(4):455-8

Women's Health Academic Centre, King's College London, London, SE1 7EH, UK.

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http://dx.doi.org/10.2217/bmm.14.22DOI Listing
December 2014

How placental growth factor detection might improve diagnosis and management of pre-eclampsia.

Expert Rev Mol Diagn 2014 May 11;14(4):403-6. Epub 2014 Apr 11.

Women's Health Academic Centre, King's College London, London SE1 7EH, UK.

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http://dx.doi.org/10.1586/14737159.2014.908121DOI Listing
May 2014

Chronic hypertension and pregnancy outcomes: systematic review and meta-analysis.

BMJ 2014 Apr 15;348:g2301. Epub 2014 Apr 15.

Division of Women's Health, Women's Health Academic Centre, King's College London and King's Health Partners, St Thomas' Hospital, London SE1 7EH, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988319PMC
http://dx.doi.org/10.1136/bmj.g2301DOI Listing
April 2014

Associations between intimate partner violence and termination of pregnancy: a systematic review and meta-analysis.

PLoS Med 2014 Jan 7;11(1):e1001581. Epub 2014 Jan 7.

Women's Health Academic Centre, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1001581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3883805PMC
January 2014

Irrational testing for antiphospholipid antibodies.

BMJ 2013 Dec 23;347:f7491. Epub 2013 Dec 23.

Guy's and St Thomas' NHS Foundation Trust, St Thomas' Hospital, London SE1 7EH, UK.

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http://dx.doi.org/10.1136/bmj.f7491DOI Listing
December 2013

Diagnostic accuracy of placental growth factor in women with suspected preeclampsia: a prospective multicenter study.

Circulation 2013 Nov;128(19):2121-31

Women's Health Academic Centre, King's College London, London, UK (L.C.C., S.D., P.T.S., M.G., A.H.S.); Maternal and Fetal Health Research Centre, University of Manchester, UK (J.M.); Oxford University Hospitals NHS Trust, Oxford, UK (L.M.); Section of Obstetrics & Gynaecology, University of Leeds, UK (N.S.); Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK (J.W.); Academic Unit of Reproductive and Developmental Medicine, University of Sheffield, UK (D.A.); The Irish Centre for Fetal and Neonatal Translational Research (INFANT), University College Cork, Ireland (L.C.K.); and Nuffield Department of Obstetrics and Gynaecology, University of Oxford, UK (C.W.G.R.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.003215DOI Listing
November 2013

Urine protein concentration estimation for biomarker discovery.

Pregnancy Hypertens 2013 Oct 5;3(4):211-4. Epub 2013 Aug 5.

Division of Women's Health, King's College London, UK.

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http://dx.doi.org/10.1016/j.preghy.2013.07.001DOI Listing
October 2013

Abnormal liver function tests in pregnancy.

BMJ 2013 Oct 25;347:f6055. Epub 2013 Oct 25.

Department of Biochemistry, Wexham Park Hospital, Slough, UK.

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http://dx.doi.org/10.1136/bmj.f6055DOI Listing
October 2013

Liver: Links between hepatobiliary diseases in and beyond pregnancy.

Nat Rev Gastroenterol Hepatol 2013 Jul 28;10(7):387-8. Epub 2013 May 28.

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http://dx.doi.org/10.1038/nrgastro.2013.92DOI Listing
July 2013

Postpartum management of hypertension.

BMJ 2013 Feb 25;346:f894. Epub 2013 Feb 25.

Maternal Medicine/Nephrology, Women's Health Academic Centre, King's College, London, UK.

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http://dx.doi.org/10.1136/bmj.f894DOI Listing
February 2013

How should women be advised on weight management in pregnancy?

BMJ 2012 May 16;344:e2774. Epub 2012 May 16.

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http://dx.doi.org/10.1136/bmj.e2774DOI Listing
May 2012

Prepregnancy care.

BMJ 2012 May 31;344:e3467. Epub 2012 May 31.

Guy's and St Thomas' NHS Foundation Trust, London, UK.

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http://dx.doi.org/10.1136/bmj.e3467DOI Listing
May 2012

Role of oxidative stress and antioxidant supplementation in pregnancy disorders.

Am J Clin Nutr 2011 Dec 25;94(6 Suppl):1980S-1985S. Epub 2011 May 25.

Division of Women's Health, King's College London, Kings Health Partners-Women's Health, Clinical Academic Grouping, London, United Kingdom.

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http://dx.doi.org/10.3945/ajcn.110.001156DOI Listing
December 2011

Pregnancy outcome in women with chronic kidney disease: a prospective cohort study.

Reprod Sci 2011 Jul 1;18(7):623-30. Epub 2011 Feb 1.

Maternal and Fetal Research Unit, Division of Reproduction and Endocrinology, King's College London School of Biomedical and Health Sciences, London, UK.

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http://dx.doi.org/10.1177/1933719110395403DOI Listing
July 2011

Adverse maternal and perinatal outcomes in women with previous preeclampsia: a prospective study.

Am J Obstet Gynecol 2011 Jun 31;204(6):512.e1-9. Epub 2011 Mar 31.

Maternal and Fetal Research Unit, Division of Women's Health, King's College London School of Medicine, London, England, UK.

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http://dx.doi.org/10.1016/j.ajog.2011.02.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121955PMC
June 2011

Should pregnant women sleep on their left?

BMJ 2011 Jun 14;342:d3659. Epub 2011 Jun 14.

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http://dx.doi.org/10.1136/bmj.d3659DOI Listing
June 2011

Advising on travel during pregnancy.

BMJ 2011 Apr 28;342:d2506. Epub 2011 Apr 28.

Division of Women's Health, King's College London School of Medicine, London, UK.

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http://dx.doi.org/10.1136/bmj.d2506DOI Listing
April 2011

Urinary proteomics for prediction of preeclampsia.

Hypertension 2011 Mar 3;57(3):561-9. Epub 2011 Jan 3.

Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary, and Life Sciences, University of Glasgow, Glasgow, UK.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.110.164285DOI Listing
March 2011

Obstetric anal sphincter injury.

BMJ 2010 Jul 9;341:c3414. Epub 2010 Jul 9.

Guy's and St Thomas' NHS Foundation Trust, London SE1 7EH.

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http://dx.doi.org/10.1136/bmj.c3414DOI Listing
July 2010

Commentary: Complex medical conditions in pregnancy need appropriate multidisciplinary input.

Authors:
Lucy C Chappell

BMJ 2009 Dec 10;339:b5179. Epub 2009 Dec 10.

Division of Reproduction and Endocrinology, King's College London, London SE1 7EH.

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http://dx.doi.org/10.1136/bmj.b5179DOI Listing
December 2009

Spontaneous preterm birth and small for gestational age infants in women who stop smoking early in pregnancy: prospective cohort study.

BMJ 2009 Mar 26;338:b1081. Epub 2009 Mar 26.

Department of Obstetrics and Gynaecology, Faculty of Medical and Health Sciences, School of Population Health, University of Auckland, Auckland, New Zealand.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2661373PMC
http://dx.doi.org/10.1136/bmj.b1081DOI Listing
March 2009

Adverse perinatal outcomes and risk factors for preeclampsia in women with chronic hypertension: a prospective study.

Hypertension 2008 Apr 7;51(4):1002-9. Epub 2008 Feb 7.

Maternal and Fetal Research Unit, Division of Reproduction and Endocrinology, King's College London School of Biomedical and Health Sciences, London SE1 7EH, UK.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.107.107565DOI Listing
April 2008

Commentary: Controversies in management of diabetes from preconception to the postnatal period.

BMJ 2008 Mar;336(7646):717-8

Division of Reproduction and Endocrinology, King's College London, London SE1 7EH.

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http://dx.doi.org/10.1136/bmj.39518.615058.AEDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276264PMC
March 2008

Vitamin C and E supplementation in women at risk of preeclampsia is associated with changes in indices of oxidative stress and placental function.

Am J Obstet Gynecol 2002 Sep;187(3):777-84

Maternal and Fetal Research Unit, Department of Obstetrics and Gynaecology and Centre for Cardiovascular Biology and Medicine, Guy's King's and St Thomas' School of Medicine, King's College, London, UK.

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September 2002

A longitudinal study of biochemical variables in women at risk of preeclampsia.

Am J Obstet Gynecol 2002 Jul;187(1):127-36

Maternal and Fetal Research Unit, Department Cardiovascular Research, Guy's King's and St Thomas' School of Medicine, King's College, London, UK.

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July 2002