Lucio Crino

Lucio Crino

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Lucio Crino

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Advances in Molecular Mechanisms and Immunotherapy Involving the Immune Cell-Promoted Epithelial-to-Mesenchymal Transition in Lung Cancer.

J Oncol 2019 19;2019:7475364. Epub 2019 Aug 19.

Biosciences Laboratory, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, Italy.

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http://dx.doi.org/10.1155/2019/7475364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6721259PMC
August 2019

Antitumor activity of larotrectinib in tumors harboring gene fusions: a short review on the current evidence.

Onco Targets Ther 2019 30;12:3171-3179. Epub 2019 Apr 30.

Department of Biomedical and Biotechnological Sciences, Pathology and Oncology Section, University of Catania, Catania, Italy.

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http://dx.doi.org/10.2147/OTT.S177051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503327PMC
April 2019

Targeting RET-rearranged non-small-cell lung cancer: future prospects.

Lung Cancer (Auckl) 2019 20;10:27-36. Epub 2019 Mar 20.

Department of Medical Oncology, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola, FC, Italy,

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http://dx.doi.org/10.2147/LCTT.S192830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433115PMC
March 2019

Epithelial-to-mesenchymal transition in the context of epidermal growth factor receptor inhibition in non-small-cell lung cancer.

Biol Rev Camb Philos Soc 2018 11 19;93(4):1735-1746. Epub 2018 Apr 19.

Department of Medical Oncology, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Via P. Maroncelli 40, 47014, Meldola, Italy.

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http://dx.doi.org/10.1111/brv.12416DOI Listing
November 2018

Precision medicine against ALK-positive non-small cell lung cancer: beyond crizotinib.

Med Oncol 2018 Apr 17;35(5):72. Epub 2018 Apr 17.

Department of Medical Oncology, Santa Maria della Misericordia Hospital, University of Perugia, Piazzale L. Severi n. 1, 06132, Perugia, Italy.

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http://dx.doi.org/10.1007/s12032-018-1133-4DOI Listing
April 2018

Nivolumab Versus Docetaxel in Previously Treated Patients With Advanced Non-Small-Cell Lung Cancer: Two-Year Outcomes From Two Randomized, Open-Label, Phase III Trials (CheckMate 017 and CheckMate 057).

J Clin Oncol 2017 Dec 12;35(35):3924-3933. Epub 2017 Oct 12.

Leora Horn, Vanderbilt-Ingram Cancer Center; David R. Spigel, Sarah Cannon Research Institute/Tennessee Oncology, Nashville, TN; Everett E. Vokes, University of Chicago, Chicago, IL; Esther Holgado, Hospital De Madrid, Norte Sanchinarro, Madrid; Enriqueta Felip, Hospital Universitari Vall d'Hebron, Barcelona; Luis Paz-Ares, Hospital Universitario Virgen Del Rocio, Seville, Spain; Neal Ready, Duke University Medical Center, Durham, NC; Martin Steins, Thoraxklinik-Heidelberg gGmbH, Heidelberg; Martin Kohlhäeufl, Robert-Bosch-Krankenhaus, Stuttgart; Martin Reck, LungenClinic Grosshansdorf, Airway Research Center North, German Center for Lung Research, Grosshansdorf; Wilfried E.E. Eberhardt, University Hospital and Ruhrlandclinic, University of Duisburg-Essen, Essen, Germany; Elena Poddubskaya, N.N. Blokhin Russian Cancer Research Center, Moscow, Russia; Hossein Borghaei, Fox Chase Cancer Center, Philadelphia, PA; Adam Pluzanski, Centrum Onkologii-Instytut Im. Marii Sklodowskiej-Curie, Warsaw, Poland; Karen L. Reckamp, City of Hope, Duarte, CA; Marco A. Burgio and Lucio Crinò, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Istituto Scientifico Romagnolo Per lo Studio e la Cura dei Tumori, Meldola, Italy; David Waterhouse, Oncology Hematology Care (OHC)/US Oncology, Cincinnati, OH; Fabrice Barlesi, Aix-Marseille Université, Assistance Publique Hôpitaux de Marseille, Marseille; Jérôme Fayette, Léon Bérard, Lyon, France; Scott Antonia, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL; Oscar Arrieta, Instituto Nacional De Cancerologia, Mexico City, Mexico; Naiyer Rizvi and Matthew D. Hellmann, Memorial Sloan Kettering Cancer Center, New York, NY; William J. Geese, Ang Li, Anne Blackwood-Chirchir, and Diane Healey, Bristol-Myers Squibb, Princeton, NJ; and Julie Brahmer, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD.

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http://dx.doi.org/10.1200/JCO.2017.74.3062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075826PMC
December 2017

Perspectives in small cell lung cancer: is something moving?

Transl Lung Cancer Res 2017 Dec;6(Suppl 1):S47-S50

Department of Medical Oncology, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Meldola, Italy.

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http://dx.doi.org/10.21037/tlcr.2017.10.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750163PMC
December 2017

Optimal management of ALK-positive NSCLC progressing on crizotinib.

Lung Cancer 2017 04 6;106:58-66. Epub 2017 Feb 6.

Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola (FC), Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S01695002173003
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http://dx.doi.org/10.1016/j.lungcan.2017.02.003DOI Listing
April 2017

The accelerated path of ceritinib: Translating pre-clinical development into clinical efficacy.

Cancer Treat Rev 2017 Apr 30;55:181-189. Epub 2017 Mar 30.

University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1016/j.ctrv.2017.03.006DOI Listing
April 2017

Pooled Analysis of CNS Response to Alectinib in Two Studies of Pretreated Patients With ALK-Positive Non-Small-Cell Lung Cancer.

J Clin Oncol 2016 12 31;34(34):4079-4085. Epub 2016 Oct 31.

Shirish M. Gadgeel, Karmanos Cancer Institute, Wayne State University, Detroit, MI; Alice T. Shaw, Massachusetts General Hospital; Leena Gandhi, Dana-Farber Cancer Institute, Boston, MA; Ramaswamy Govindan, Washington University School of Medicine, St Louis, MO; Mark A. Socinski, University of Pittsburgh, Pittsburgh, PA; D. Ross Camidge, University of Colorado Cancer Center, Denver, CO; Alberto Chiappori, Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL; Sai-Hong Ignatius Ou, University of California at Irvine, Orange, CA; Luigi De Petris, Karolinska Institutet, Stockholm, Sweden; Dong-Wan Kim, Seoul National University Hospital, Seoul; Ji-Youn Han, Lung Cancer Centre, National Cancer Centre, Goyang, South Korea; Denis L. Moro-Sibilot, Service de Pneumologie; Michael Duruisseaux, Centre Hospitalier Universitaire de Grenoble, Grenoble; Eric Dansin, Centre Oscar Lambret, Lille, France; Lucio Crino, Santa Maria della Misericordia Hospital, Perugia; Tommaso De Pas, European Institute of Oncology, Milan, Italy; Antje Tessmer, Evangelische Lungenklinik Berlin, Berlin, Germany; James Chih-Hsin Yang, Graduate Institute of Oncology and Cancer Research Centre, National Taiwan University, Taipei, Taiwan; and Walter Bordogna, Sophie Golding, and Ali Zeaiter, F. Hoffmann-La Roche, Basel, Switzerland.

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http://dx.doi.org/10.1200/JCO.2016.68.4639DOI Listing
December 2016

Malignant giant solitary fibrous tumor of the pleura metastatic to the thyroid gland.

Tumori 2016 Nov 11;102(Suppl. 2). Epub 2016 Nov 11.

Department of Medical Oncology, Santa Maria della Misericordia Hospital, Perugia - Italy.

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http://dx.doi.org/10.5301/tj.5000514DOI Listing
November 2016

Alectinib's activity against CNS metastases from ALK-positive non-small cell lung cancer: a single institution case series.

J Neurooncol 2016 09 20;129(2):355-61. Epub 2016 Jun 20.

Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, via Dottori, 1, 06156, Perugia, Italy.

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http://dx.doi.org/10.1007/s11060-016-2184-zDOI Listing
September 2016

Osimertinib (AZD9291) and CNS Response in Two Radiotherapy-Naïve Patients with EGFR-Mutant and T790M-Positive Advanced Non-Small Cell Lung Cancer.

Clin Drug Investig 2016 Aug;36(8):683-6

Department of Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, via Dottori 1, 06156, Perugia, Italy.

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http://dx.doi.org/10.1007/s40261-016-0411-1DOI Listing
August 2016

Multicenter Phase II Study of Whole-Body and Intracranial Activity With Ceritinib in Patients With ALK-Rearranged Non-Small-Cell Lung Cancer Previously Treated With Chemotherapy and Crizotinib: Results From ASCEND-2.

J Clin Oncol 2016 08 18;34(24):2866-73. Epub 2016 Jul 18.

Lucio Crinò, University Medical School of Perugia, Azienda Ospedale Perugia, Perugia; Filippo De Marinis, European Institute of Oncology, Milan; Giorgio Scagliotti, University of Torino, Torino, Italy; Myung-Ju Ahn, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, South Korea; Harry J.M. Groen, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands; Heather Wakelee, Stanford University Medical Center, Stanford, CA; Toyoaki Hida, Aichi Cancer Center, Nagoya; Makoto Nishio, Japanese Foundation for Cancer Research, Tokyo, Japan; Tony Mok, Chinese University of Hong Kong, Shatin, China; David Spigel, Sarah Cannon Research Institute, Nashville, TN; Enriqueta Felip, Vall d'Hebron University, Barcelona, Spain; Fabrice Branle and Massimiliano Quadrigli, Novartis Pharma AG, Basel, Switzerland; Chetachi Emeremni and Jie Zhang, Novartis Pharma, East Hanover, NJ; and Alice T. Shaw, Massachusetts General Hospital, Boston MA.

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http://ascopubs.org/doi/10.1200/JCO.2015.65.5936
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http://dx.doi.org/10.1200/JCO.2015.65.5936DOI Listing
August 2016

Pharmacotherapeutic options for treating brain metastases in non-small cell lung cancer.

Expert Opin Pharmacother 2015 6;16(17):2601-13. Epub 2015 Oct 6.

a 1 Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia , Perugia, Italy +39 07 55 78 41 85 ; +39 07 55 78 41 84 ;

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http://dx.doi.org/10.1517/14656566.2015.1094056DOI Listing
June 2016

Targeting EGFR and ALK in NSCLC: current evidence and future perspective.

Lung Cancer Manag 2016 Jun 23;5(2):79-90. Epub 2016 Jun 23.

Department of Medical Oncology, S Maria della Misericordia Hospital, Perugia/Italy.

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https://www.futuremedicine.com/doi/10.2217/lmt-2016-0005
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http://dx.doi.org/10.2217/lmt-2016-0005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310340PMC
June 2016

Pharmacokinetics of trastuzumab in haemodialysis.

Breast J 2015 May-Jun;21(3):329-31. Epub 2015 Mar 19.

Department of Medical Oncology, Ospedale Sacro Cuore Don Calabria, Negrar-Verona, Italy.

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http://dx.doi.org/10.1111/tbj.12407DOI Listing
May 2016

Targeting the KRAS variant for treatment of non-small cell lung cancer: potential therapeutic applications.

Expert Rev Respir Med 2016 17;10(1):53-68. Epub 2015 Nov 17.

a Medical Oncology , Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia , Perugia , Italy.

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http://dx.doi.org/10.1586/17476348.2016.1115349DOI Listing
May 2016

Long noncoding RNAs: new insights into non-small cell lung cancer biology, diagnosis and therapy.

Med Oncol 2016 Feb 19;33(2):18. Epub 2016 Jan 19.

Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Via Dottori 1, 06156, Perugia, Italy.

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http://dx.doi.org/10.1007/s12032-016-0731-2DOI Listing
February 2016

Adjuvant Erlotinib Versus Placebo in Patients With Stage IB-IIIA Non-Small-Cell Lung Cancer (RADIANT): A Randomized, Double-Blind, Phase III Trial.

J Clin Oncol 2015 Dec 31;33(34):4007-14. Epub 2015 Aug 31.

Karen Kelly, University of California, Davis, Comprehensive Cancer Center, Sacramento, CA; Nasser K. Altorki, New York Presbyterian Hospital-Weill Cornell Medical Center, New York, NY; Wilfried E.E. Eberhardt, University Hospital Essen, Essen, Germany; Mary E.R. O'Brien, Royal Marsden Hospital, London, United Kingdom; David R. Spigel, Sarah Cannon Research Institute, Nashville, TN; Lucio Crinò, Ospedale S. Maria della Misericordia, Perugia, Italy; Chun-Ming Tsai, Taipei General Hospital and National Yang-Ming University, Taipei, Taiwan; Joo-Hang Kim, Yonsei University Health System, Seoul; Eun Kyung Cho, Gachon University, Incheon, Korea; Philip C. Hoffman, The University of Chicago Medical Center, Chicago; Jiuzhou Wang and Margaret A. Foley, Astellas Pharma, Northbrook, IL; Sergey V. Orlov, I.P. Pavlov Medical University, St Petersburg, Russia; Piotr Serwatowski, Specjalistyczny Szpital, Sokolowskiego, Szczecin, Poland; Julie D. Horan, Novella Clinical, Boulder, CO; and Frances A. Shepherd, Princess Margaret Cancer Centre, University of Toronto, Toronto, Ontario, Canada.

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http://jco.ascopubs.org/content/early/2015/08/31/JCO.2015.61
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2015.61.8918
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http://dx.doi.org/10.1200/JCO.2015.61.8918DOI Listing
December 2015

Assessment of EGFR mutations in circulating tumor cell preparations from NSCLC patients by next generation sequencing: toward a real-time liquid biopsy for treatment.

PLoS One 2014 19;9(8):e103883. Epub 2014 Aug 19.

Center of Predictive Molecular Medicine, Center of Excellence on Aging, University-Foundation, Chieti, Italy; Oncological and Cardiovascular Molecular Medicine Unit, Center of Excellence on Aging, University-Foundation, Chieti, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0103883PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138040PMC
October 2015

Early Prediction of Response to Tyrosine Kinase Inhibitors by Quantification of EGFR Mutations in Plasma of NSCLC Patients.

J Thorac Oncol 2015 Oct;10(10):1437-43

*Center of Predictive Molecular Medicine, Ce.S.I., G. D'Annunzio University-Foundation, Chieti, Italy; †Medical Scientific Affairs Department, Roche Molecular Systems, Pleasanton, California; ‡Oncological and Cardiovascular Molecular Medicine Unit, Ce.S.I., G. D'Annunzio University-Foundation, Chieti, Italy; §Division of Thoracic Oncology, European Institute of Oncology, Milan, Italy; ‖Department of Medical Oncology, S. Maria della Misericordia Hospital, Perugia, Italy; ¶Department of Medical Oncology, Bellaria-Maggiore Hospital, Azienda USL of Bologna, Bologna, Italy; #Unit of Pneumology, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy; **Ospedale Civile di Pescara, Pescara, Italy; ††Ospedale Civile di Sulmona, Sulmona, Italy; ‡‡Department of Medical Oncology, Consorzio Interuniversitario Nazionale per la Bio-Oncologia, G. d'Annunzio University, Chieti, Italy; §§Department of Oncology-Haematology, Humanitas Cancer Center, IRCCS, Milan, Italy; and ‖‖Perugia University Medical School, Perugia, Italy.

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http://dx.doi.org/10.1097/JTO.0000000000000643DOI Listing
October 2015

Nivolumab versus Docetaxel in Advanced Nonsquamous Non-Small-Cell Lung Cancer.

N Engl J Med 2015 Oct 27;373(17):1627-39. Epub 2015 Sep 27.

From the Fox Chase Cancer Center, Philadelphia (H.B.); Hospital Universitario Virgen del Rocio, Seville (L.P.-A.), Vall d'Hebron University Hospital and Vall d'Hebron Institute of Oncology, Barcelona (E.F.), and Hospital de Madrid, Norte Sanchinarro, Madrid (E.H.) - all in Spain; Vanderbilt-Ingram Cancer Center (L.H.), and Sarah Cannon Research Institute and Tennessee Oncology (D.R.S.) - both in Nashville; Thoraxklinik, Heidelberg University Hospital, Heidelberg (M.S.) and Robert-Bosch-Krankenhaus Stuttgart, Gerlingen (M.K.) - both in Germany; Duke University Medical Center, Durham, NC (N.E.R.); University of Washington, Seattle (L.Q.C.); University of Chicago Medicine and Biological Sciences, Chicago (E.E.V.); Aix Marseille University, Assistance Publique-Hôpitaux de Marseille, Marseille (F.B.), Centre Léon Bérard, Lyon (J.F.), and Centre Hospitalier Universitaire de Rennes, Rennes (H.L.) - all in France; Instituto Nacional de Cancerologia, Mexico City (O.A.); Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori IRCCS, Meldola, Forlì-Cesena (M.A.B.), and Ospedale di Perugia, Perugia (L.C.) - both in Italy; N.N. Blokhin Russian Cancer Research Center, Moscow (E.P.); University of Texas Southwestern Medical Center, Dallas (D.E.G.); Yale Comprehensive Cancer Center, New Haven, CT (S.N.G.); Memorial Sloan Kettering Cancer Center, New York (C.M.R., N.R.); University of Texas M.D. Anderson Cancer Center, Houston (G.R.B.); H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL (S.J.A.); Bristol-Myers Squibb, Princeton, NJ (C.D., C.T.H., F.G.F.); and the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore (J.R.B.).

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http://dx.doi.org/10.1056/NEJMoa1507643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705936PMC
October 2015

Dyskerin and TERC expression may condition survival in lung cancer patients.

Oncotarget 2015 Aug;6(25):21755-60

Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, Bologna, I-40138, Italy.

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http://dx.doi.org/10.18632/oncotarget.4580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673301PMC
August 2015

Nivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung Cancer.

N Engl J Med 2015 Jul 31;373(2):123-35. Epub 2015 May 31.

From the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore (J.B.); the City of Hope Comprehensive Cancer Center, Duarte, CA (K.L.R.); the Netherlands Cancer Institute and Antoni van Leeuwenhoek Hospital, Amsterdam (P.B.), Erasmus MC Cancer Institute, Rotterdam (J.G.A.), and Ziekenhuis Amphia, Breda (J.G.A.) - all in the Netherlands; the University Hospital of Perugia, Perugia (L.C.), and the Fondazione IRCCS Istituto Nazionale dei Tumori, Milan (M.C.G.) - both in Italy; the Department of Medical Oncology, West German Cancer Center, Universitätsklinikum Essen, and the Ruhrlandklinik, Universität Duisburg-Essen, Essen (W.E.E.E.), the Thoraxklinik, Heidelberg University Hospital, Heidelberg (M.S.), and the LungenClinic Grosshansdorf, Grosshansdorf (M.R.) - all in Germany; the N.N. Blokhin Russian Cancer Research Center, Moscow (E.P.); the H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL (S.A.); the Centrum Onkologii-Instytut im. Marii Skłodowskiej-Curie, Warsaw, Poland (A.P.); the University of Chicago Medicine and Biological Sciences, Chicago (E.E.V.); the Hospital Madrid Norte Sanchinarro (E.H.), the Hospital Universitario Fundación Jiménez Díaz, Madrid (M.D.), and the Hospital Universitario Virgen Del Rocío, Seville (L.P.-A.) - all in Spain; Oncology Hematology Care, Cincinnati (D.W.); the Duke University Medical Center, Durham, NC (N.R.); Massachusetts General Hospital, Boston (J.G.); Centro Internacional de Estudios Clinicos, Santiago, Chile (O.A.F.); Nemocnice Na Bulovce, Prague, Czech Republic (L.H.); Bristol-Myers Squibb, Princeton, NJ (C.B., C.T.H., B.L.); and the Sarah Cannon Research Institute and Tennessee Oncology, Nashville (D.R.S.).

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http://dx.doi.org/10.1056/NEJMoa1504627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681400PMC
July 2015

Clinical Experience With Crizotinib in Patients With Advanced ALK-Rearranged Non-Small-Cell Lung Cancer and Brain Metastases.

J Clin Oncol 2015 Jun 26;33(17):1881-8. Epub 2015 Jan 26.

Daniel B. Costa, Beth Israel Deaconess Medical Center, Harvard Medical School; Alice T. Shaw, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Sai-Hong I. Ou, Chao Family Comprehensive Cancer Center, University of California Irvine School of Medicine, Irvine; S. Martin Shreeve, Paulina Selaru, and Keith D. Wilner, Pfizer Oncology, La Jolla, CA; Benjamin J. Solomon, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia; Gregory J. Riely, Memorial Sloan-Kettering Cancer Center; Patrick Schnell, Pfizer Oncology, New York, NY; Myung-Ju Ahn, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea; Caicun Zhou, Shanghai Pulmonary Hospital, Shanghai, People's Republic of China; Anna Polli, Pfizer Oncology, Milan; Lucio Crinò, Perugia University Medical School, Perugia, Italy; Robin Wiltshire, Pfizer Oncology, Tadworth, United Kingdom; and D. Ross Camidge, University of Colorado Denver, Aurora, CO.

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http://dx.doi.org/10.1200/JCO.2014.59.0539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451171PMC
June 2015

CSF Concentration of Crizotinib in Two ALK-Positive Non-Small-Cell Lung Cancer Patients with CNS Metastases Deriving Clinical Benefit from Treatment.

J Thorac Oncol 2015 May;10(5):e26-7

*Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy; †Medical Oncology, Sacro Cuore-Don Calabria Hospital, Negrar, VR, Italy; ‡Neuroradiology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy; and §dto-LABS, Agilent Partner Lab, Resana, TV, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S15560864153240
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http://dx.doi.org/10.1097/JTO.0000000000000468DOI Listing
May 2015

MYC and human telomerase gene (TERC) copy number gain in early-stage non-small cell lung cancer.

Am J Clin Oncol 2015 Apr;38(2):152-8

*Department of Medical Oncology, S. Maria della Misericordia Hospital Departments of †Electronic and Information Engineering ‡Thoracic Surgery §Institute of Pathological Anatomy and Histology, University of Perugia, Perugia, Italy ∥Department of Medicine/Medical Oncology, University of Colorado Cancer Center, Aurora, CO.

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http://dx.doi.org/10.1097/COC.0000000000000012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4607281PMC
April 2015

Future options for ALK-positive non-small cell lung cancer.

Lung Cancer 2015 Mar 3;87(3):211-9. Epub 2015 Jan 3.

Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy.

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http://dx.doi.org/10.1016/j.lungcan.2014.12.017DOI Listing
March 2015

Crizotinib therapy for advanced lung adenocarcinoma and a ROS1 rearrangement: results from the EUROS1 cohort.

J Clin Oncol 2015 Mar 9;33(9):992-9. Epub 2015 Feb 9.

Julien Mazières, Damien Rouvière, and Julie D. Milia, Hôpital Larrey, Centre Hospitalier Universitaire, Université Paul Sabatier; Thomas Filleron, Institut Universitaire du Cancer, Toulouse; Gérard Zalcman, Centre Hospitalier Universitaire, Université de Caen-Basse Normandie, Caen; Pamela Biondani and Benjamin Besse, Gustave Roussy, Villejuif; Fabrice Barlesi, Aix-Marseille University, Assistance Publique Hôpitaux de Marseille, Marseille; Hervé Léna, Centre Hospitalier Universitaire, Rennes; Isabelle Monnet, Centre Hospitalier Intercommunal de Créteil, Créteil; Luc Thiberville, Centre Hospitalier Universitaire, Rouen; Nicolas Pecuchet, Institut Curie, Paris, France; Lucio Crinò, Medica-Azienda Ospedaliera, Perugia; Federico Cappuzzo, Istituto Toscano Tumori, Ospedale Civile, Livorno, Italy; Anne-Marie C. Dingemans, Maastricht University Medical Center, Maastricht; Egbert F. Smit, VU University Medical Center, Amsterdam, the Netherlands; Sacha I. Rothschild, University Hospital Basel, Medical Oncology, Basel; Christian Spirig, Klinik St Anna; Joachim Diebold and Oliver Gautschi, Cantonal Hospital Luzern, Lucerne, Switzerland; Rafal Dziadziuszko, Gdansk Medical University, Gdansk, Poland; Jurgen Wolf and Roman K. Thomas, Center of Integrated Oncology Köln-Bonn, University Hospital Cologne, University of Cologne; Frauke Leenders and Roman K. Thomas, University of Cologne; Johannes M. Heuckmann, Blackfield AG, Cologne, Germany.

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http://jco.ascopubs.org/content/early/2015/02/03/JCO.2014.58
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http://jco.ascopubs.org/content/early/2015/02/03/JCO.2014.58
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http://jco.ascopubs.org/cgi/doi/10.1200/JCO.2014.58.3302
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http://dx.doi.org/10.1200/JCO.2014.58.3302DOI Listing
March 2015

Perspectives of novel imaging techniques for staging, therapy response assessment, and monitoring of surveillance in lung cancer: summary of the Dresden 2013 Post WCLC-IASLC State-of-the-Art Imaging Workshop.

J Thorac Oncol 2015 Feb;10(2):237-49

*Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; †Division of Thoracic Surgery, Royal Brompton Hospital, Imperial College London, London, United Kingdom; ‡Department of Radiation Oncology, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; §Department of Medicine I, Medical University of Vienna, Vienna, Austria; ║Division of Thoracic Surgery, University Hospital of Zurich, Zurich, Switzerland; ¶Medical Oncology Division, Department of Oncology, University Hospital Perugia, Perugia, Italy; #Lung Cancer Research, University of Leicester & Leicester University Hospitals, Leicester, United Kingdom; **Department of Radiology, General Hospital Celle, Celle, Germany; ††Department of Thoracic and Vascular Surgery, Hôpital Tenon, University of Paris VI, Paris, France; ‡‡Department of Surgery/Thoracic Oncology, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; §§Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; ║║Department of Radiation Oncology, VU University Medical Center Amsterdam, Amsterdam, The Netherlands; ¶¶Department of Pneumology, Respiratory Oncology Unit and Trial Unit, University Hospital KU Leuven, Leuven, Belgium; ##Clinical Competence Center Oncology, Siemens AG, Erlangen, Germany; ***Institute of Clinical Radiology and Nuclear Medicine/Department of Molecular Imaging & Radiopharmacy, University Medical Centre Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; †††Roswell Park Cancer Institute, Elm & Carlton Streets, Buffalo, NY 14263.

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http://dx.doi.org/10.1097/JTO.0000000000000412DOI Listing
February 2015

Non-coding RNAs in lung cancer.

Oncoscience 2014 15;1(11):674-705. Epub 2014 Nov 15.

Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4278269PMC
http://dx.doi.org/10.18632/oncoscience.98DOI Listing
January 2015

ALK rearrangement testing by FISH analysis in non-small-cell lung cancer patients: results of the first italian external quality assurance scheme.

J Thorac Oncol 2014 Oct;9(10):1470-6

*Center of Predictive Molecular Medicine, Center of Excellence on Aging, University-Foundation, Chieti, Italy; †Division of Pathology and Laboratory Medicine, European Institute of Oncology, Milan, Italy; ‡Division of Anatomic Pathology, San Luigi Hospital and University of Turin, Orbassano, Italy; §Pathology Department, Policlinico di Modena, Modena, Italy; ‖Diagnostic and Laboratory Medicine, INT-Fondazione "G.Pascale", Naples, Italy; ¶Medical Oncology Unit, University Hospital, Parma, Italy; #Department of Medical Oncology, Perugia Hospital, Perugia, Italy; **Division of Medical Oncology, S.G. Moscati Hospital, Avellino, Italy; ††Department of Human Pathology and Oncology, University of Florence, Florence, Italy; ‡‡Pathology Department, Casa di Cura San Pio X and I.R.C.C.S. Policlinico San Donato, Milano, Italy; §§Thoracic Oncology Unit, University of Torino, San Luigi Hospital, Torino, Italy; ‖‖Cell Biology and Biotherapy Unit, INT-Fondazione "G.Pascale", Naples, Italy; and ¶¶Medical Oncology Unit, S. Orsola-Malpighi Hospital, Bologna, Italy.

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http://dx.doi.org/10.1097/JTO.0000000000000280DOI Listing
October 2014

Postsurgical follow-up is always necessary in bronchial carcinoid.

Ann Thorac Surg 2014 Sep;98(3):1143-4

Multidisciplinary Neuroendocrine Tumors Center, European Neuroendocrine Tumor Society Center of Excellence, Umbria Regional Cancer Network, Via E. dal Pozzo, 06126Perugia, Italy.

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http://dx.doi.org/10.1016/j.athoracsur.2014.04.020DOI Listing
September 2014

Impact of epidermal growth factor receptor and KRAS mutations on clinical outcome in resected non-small cell lung cancer patients.

Am J Clin Oncol 2014 Aug;37(4):343-9

*Thoracic Surgery Unit ∥Institute of Pathological Anatomy and Histology, University of Perugia Medical School †Medical Oncology Division, S. Maria della Misericordia Hospital ‡Department of Electronic and Information Engineering, University of Perugia, Perugia §Thoracic Surgery Unit, S. Camillo Forlanini Hospital, Roma, Italy.

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http://dx.doi.org/10.1097/COC.0b013e31827a7e7aDOI Listing
August 2014

A prospective study on survival in cancer patients with and without venous thromboembolism.

Intern Emerg Med 2014 Aug 14;9(5):559-67. Epub 2013 Aug 14.

Internal and Cardiovascular Medicine-Stroke Unit, University of Perugia, Perugia, Italy.

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http://dx.doi.org/10.1007/s11739-013-0985-zDOI Listing
August 2014

Phase II randomized study of vandetanib plus gemcitabine or gemcitabine plus placebo as first-line treatment of advanced non-small-cell lung cancer in elderly patients.

J Thorac Oncol 2014 May;9(5):733-7

*Division of Medical Oncology, "SG Moscati" Hospital, Avellino, Italy; †Department of Oncology, University of Turin, AOU San Luigi Orbassano, Turin, Italy; ‡Medical Oncology 1, "Fondazione IRCCS Istituto Nazionale dei Tumori", Milan, Italy; §Department of Oncology, San Paolo Hospital, Milan, Italy; ‖Second Medical Oncology Unit, "Istituto Oncologico Veneto", Padua, Italy; ¶European Institute of Oncology, Milan, Italy; #Department of Oncology, IRCCS Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (I.R.S.T.), Meldola (FC), Italy; **Division of Medical Oncology, S. Maria della Misericordia Hospital, Perugia, Italy; ††Lung Cancer Unit, National Institute for Cancer Research, Genoa, Italy; ‡‡Medical Oncology Department, Santa Chiara Hospital, Trento, Italy; §§Medical Oncology Unit, San Vincenzo Hospital, Taormina, Catania, Italy; ‖‖Oncology Unit, Santa Maria delle Croci Hospital, Ravenna, Italy; ¶¶Medical Oncology Department, AUSL Bologna, Italy; ##Medical Oncology Unit, "Giovanni Paolo II" National Cancer Centre, Bari, Italy; ***Department of Oncology, Azienda Ospedaliera Treviglio, Treviglio (BG), Italy; †††Department of Oncology, University Hospital of Udine, Udine, Italy; ‡‡‡Department of Oncology, Ospedale Niguarda Ca' Granda, Milan, Italy; §§§AstraZeneca, Basiglio (MI), Italy; ‖‖‖LB Research, Cantù (CO), Italy; and ¶¶¶Medical Oncology, Second University of Naples, Naples, Italy.

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http://dx.doi.org/10.1097/JTO.0000000000000120DOI Listing
May 2014

Therapeutic options targeting angiogenesis in nonsmall cell lung cancer.

Eur Respir Rev 2014 Mar;23(131):79-91

Division of Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy.

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http://dx.doi.org/10.1183/09059180.00008913DOI Listing
March 2014

DKC1 gene mutations in human sporadic cancer.

Histol Histopathol 2013 03;28(3):365-72

Department of Experimental Pathology, Alma Mater Studiorum, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.14670/HH-28.365DOI Listing
March 2013

Selumetinib: a promising pharmacologic approach for KRAS-mutant advanced non-small-cell lung cancer.

Future Oncol 2013 Feb;9(2):167-77

Division of Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, via Dottori 1, 06156 Perugia, Italy.

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http://dx.doi.org/10.2217/fon.12.198DOI Listing
February 2013