Lucie Lafay-Cousin

Lucie Lafay-Cousin

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Lucie Lafay-Cousin

Lucie Lafay-Cousin

Publications by authors named "Lucie Lafay-Cousin"

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52Publications

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The Pediatric Toronto Extremity Salvage Score (pTESS): Validation of a Self-reported Functional Outcomes Tool for Children with Extremity Tumors.

Clin Orthop Relat Res 2019 Sep;477(9):2127-2141

J. Piscione, W. Barden, Rehabilitation Department, Hospital for Sick Children, Toronto, Canada J. Barry, H. Saint-Yves, M. Isler, S. Mottard, Service d'orthopédie, Hôpital Maisonneuve-Rosemont et Université de Montréal, Montréal, Canada A. Malkin, T. Roy, S. Hopyan, Division of Orthopaedic Surgery, Hospital for Sick Children, Toronto, Canada T. Sueyoshi, C. Strahlendorf, Division of Hematology and Oncology, BC Children's Hospital and University of British Columbia, Vancouver, Canada K. Mazil, P. Giuliano, L. Lafay-Cousin, Department of Oncology, Alberta Children's Hospital and University of Calgary, Calgary, Canada S. Salomon, F. Dandachli, R. E. Turcotte, Divisions of Orthopaedic Surgery and Surgical Oncology, McGill University Health Centre and McGill University, Montréal, Canada A. Griffin, P. Ferguson, Division of Orthopaedic Surgery, Mt Sinai Hospital and University of Toronto, Toronto, Canada A. Gupta, Division of Haematology/Oncology, Hospital for Sick Children, Toronto, Canada K. Scheinemann, Division of Hematology/Oncology, McMaster University Health Sciences Centre, Hamilton, Canada M. Ghert, Division of Orthopaedic Surgery, Juravinski Cancer Centre and McMaster University, Hamilton, Canada J. Werier, Division of Paediatric Orthopaedic Surgery, Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, Canada S. Afzal, Division of Hematology/Oncology, IWK Health Centre and Dalhousie University, Halifax, Canada M. E. Anderson, Orthopedic Center, Boston Children's Hospital, Jimmy Fund Clinic/Dana Farber Cancer Institute and Harvard Medical School, Boston, MA, USA S. Hopyan, Program in Developmental and Stem Cell Biology, Hospital for Sick Children, Departments of Surgery and Molecular Genetics, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1097/CORR.0000000000000756DOI Listing
September 2019

A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor.

Cancer Cell 2019 Jul;36(1):51-67.e7

Arthur and Sonia Labatt Brain Tumor Research Centre, Division of Haematology/Oncology, Hospital for Sick Children, Toronto, ON M5G0A4, Canada; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, ON M5S1A8, Canada; Division of Hematology-Oncology, The Hospital for Sick Children, Department of Pediatrics, University of Toronto, Toronto, ON M5G0A4, Canada; Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, ON M5G1L7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.06.002DOI Listing
July 2019

Patient-Reported Outcomes in Psychological Treatment for an Adolescent Oncology Patient: A Case Report.

J Adolesc Young Adult Oncol 2018 06 5;7(3):395-399. Epub 2018 Jan 5.

2 Hematology, Oncology, and Transplant Program, Alberta Children's Hospital , Calgary, Canada .

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http://dx.doi.org/10.1089/jayao.2017.0090DOI Listing
June 2018

Optic neuropathy in the context of leukemia or lymphoma: diagnostic approach to a neuro-oncologic emergency.

Neurooncol Pract 2017 Mar 9;4(1):60-66. Epub 2016 Dec 9.

Department of Pediatrics, Section of Neurology; Alberta Children's Hospital, University of Calgary, Cumming School of Medicine, Calgary, Alberta, Canada (K.A.M.); Department of Pathology & Laboratory Medicine; Foothills Hospital, University of Calgary, Cumming School of Medicine, Calgary, Alberta, Canada (A.N.); Department of Ophthalmology; Alberta Children's Hospital, University of Calgary, Cumming School of Medicine, Calgary, Alberta, Canada (K.R); Department of Ophthalmology and Visual Sciences, University of Alberta, Faculty of Medicine and Dentistry, Edmonton, Alberta, Canada (E.W.); Departments of Pathology & Laboratory Medicine and Pediatrics; Alberta Children's Hospital, University of Calgary, Cumming School of Medicine, Calgary, Alberta, Canada (M.-A.B.); Departments of Oncology and Pediatrics; Alberta Children's Hospital, University of Calgary, Cumming School of Medicine, Calgary, Alberta, Canada (L.L.-C.); Department of Clinical Neurosciences; Foothills Hospital, University of Calgary, Cumming School of Medicine, Calgary, Alberta, Canada (F.C.).

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http://dx.doi.org/10.1093/nop/npw006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6655480PMC
March 2017

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.

Authors:
Jonathon Torchia Brian Golbourn Shengrui Feng King Ching Ho Patrick Sin-Chan Alexandre Vasiljevic Joseph D Norman Paul Guilhamon Livia Garzia Natalia R Agamez Mei Lu Tiffany S Chan Daniel Picard Pasqualino de Antonellis Dong-Anh Khuong-Quang Aline C Planello Constanze Zeller Dalia Barsyte-Lovejoy Lucie Lafay-Cousin Louis Letourneau Mathieu Bourgey Man Yu Deena M A Gendoo Misko Dzamba Mark Barszczyk Tiago Medina Alexandra N Riemenschneider A Sorana Morrissy Young-Shin Ra Vijay Ramaswamy Marc Remke Christopher P Dunham Stephen Yip Ho-Keung Ng Jian-Qiang Lu Vivek Mehta Steffen Albrecht Jose Pimentel Jennifer A Chan Gino R Somers Claudia C Faria Lucia Roque Maryam Fouladi Lindsey M Hoffman Andrew S Moore Yin Wang Seung Ah Choi Jordan R Hansford Daniel Catchpoole Diane K Birks Nicholas K Foreman Doug Strother Almos Klekner Laszló Bognár Miklós Garami Péter Hauser Tibor Hortobágyi Beverly Wilson Juliette Hukin Anne-Sophie Carret Timothy E Van Meter Eugene I Hwang Amar Gajjar Shih-Hwa Chiou Hideo Nakamura Helen Toledano Iris Fried Daniel Fults Takafumi Wataya Chris Fryer David D Eisenstat Katrin Scheinemann Adam J Fleming Donna L Johnston Jean Michaud Shayna Zelcer Robert Hammond Samina Afzal David A Ramsay Nongnuch Sirachainan Suradej Hongeng Noppadol Larbcharoensub Richard G Grundy Rishi R Lulla Jason R Fangusaro Harriet Druker Ute Bartels Ronald Grant David Malkin C Jane McGlade Theodore Nicolaides Tarik Tihan Joanna Phillips Jacek Majewski Alexandre Montpetit Guillaume Bourque Gary D Bader Alyssa T Reddy G Yancey Gillespie Monika Warmuth-Metz Stefan Rutkowski Uri Tabori Mathieu Lupien Michael Brudno Ulrich Schüller Torsten Pietsch Alexander R Judkins Cynthia E Hawkins Eric Bouffet Seung-Ki Kim Peter B Dirks Michael D Taylor Anat Erdreich-Epstein Cheryl H Arrowsmith Daniel D De Carvalho James T Rutka Nada Jabado Annie Huang

Cancer Cell 2016 Dec;30(6):891-908

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5G0A4, Canada; Department of Paediatrics, University of Toronto, Toronto, ON M5G0A4, Canada; Division of Hematology/Oncology, Hospital for Sick Children, Toronto, ON M5G1X8, Canada; Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, Toronto, ON M5G1X8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500911PMC
December 2016

Phase II Weekly Vinblastine for Chemotherapy-Naïve Children With Progressive Low-Grade Glioma: A Canadian Pediatric Brain Tumor Consortium Study.

J Clin Oncol 2016 10;34(29):3537-3543

Alvaro Lassaletta, Cynthia E. Hawkins, Rahul Krishnatry, Matthew Mistry, Anthony Arnoldo, Vijay Ramaswamy, Annie Huang, Ute Bartels, Uri Tabori, and Eric Bouffet, The Hospital for Sick Children, Toronto; Katrin Scheinemann, McMaster Children's Hospital; Shayna M. Zelcer, Children's Hospital of Western Ontario, London; Gregory Russell Pond, Ontario Clinical Oncology Group, McMaster University, Hamilton; Daniel Keene and Donna L. Johnston, Children's Hospital of Eastern Ontario, Ottawa, Ontario; Juliette Hukin and Ken Poskitt, British Columbia Children's Hospital, Vancouver, British Columbia; Beverley A. Wilson, University of Alberta Hospital; Lucie Lafay-Cousin, Alberta Children's Hospital, Calgary; David D. Eisenstat, Stollery Children's Hospital, Edmonton; Alberta; Nada Jabado, McGill University; Anne Sophie Carret, Hospital Sainte Justine, Montreal; Valerie Larouche, Centre Hospitalier Universitaire de Québec, Québec, Québec; and David D. Eisenstat, Cancer Care Manitoba, Winnipeg, Manitoba, Canada.

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http://dx.doi.org/10.1200/JCO.2016.68.1585DOI Listing
October 2016

Carboplatin Rechallenge After Hypersensitivity Reactions in Pediatric Patients With Low-Grade Glioma: How Far Should we Push?

Pediatr Blood Cancer 2016 Jan 9;63(1):9-10. Epub 2015 Oct 9.

Division of Hematology Oncology Bone Marrow Transplantation, Alberta Children's Hospital, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1002/pbc.25758DOI Listing
January 2016

Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis.

Lancet Oncol 2015 May 14;16(5):569-82. Epub 2015 Apr 14.

Division of Hematology-Oncology, University of Toronto, Toronto, ON, Canada; Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada; Department of Pediatrics, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(15)70114-2DOI Listing
May 2015

Incidence of medulloblastoma in Canadian children.

J Neurooncol 2014 Dec 17;120(3):575-9. Epub 2014 Aug 17.

Division of Pediatric Hematology/Oncology, Children's Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada,

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http://dx.doi.org/10.1007/s11060-014-1588-xDOI Listing
December 2014

Ependymoma in children under the age of 3 years: a report from the Canadian Pediatric Brain Tumour Consortium.

J Neurooncol 2014 Apr 16;117(2):359-64. Epub 2014 Feb 16.

Pediatric Oncology and Blood and Marrow Transplant, Alberta Children's Hospital, 2888 Shaganappi Trail NW, Calgary, AB, T3B 6A8, Canada.

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http://dx.doi.org/10.1007/s11060-014-1396-3DOI Listing
April 2014

Post-chemotherapy maturation in supratentorial primitive neuroectodermal tumors.

Brain Pathol 2014 Mar 27;24(2):166-72. Epub 2013 Nov 27.

Division of Pediatric Hematology Oncology and Bone Marrow Transplantation, Alberta Children's Hospital, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1111/bpa.12089DOI Listing
March 2014

Benefit from prolonged dose-intensive chemotherapy for infants with malignant brain tumors is restricted to patients with ependymoma: a report of the Pediatric Oncology Group randomized controlled trial 9233/34.

Neuro Oncol 2014 Mar 12;16(3):457-65. Epub 2013 Dec 12.

University of Calgary, Calgary, Canada (D.R.S., L.L.-C.); St Jude Children's Research Hospital, Memphis, Tennessee (J.M.B., L.E.K., A.G.); Johns Hopkins University, Baltimore, Maryland (P.B.); Dell Children's Medical Center of Central Texas, Austin, Texas (P.A.); University of Rochester, Rochester, New York (L.C.); (retired) Roswell Park Cancer Institute, Buffalo, New York (P.D.); University of Tennessee Health Science Center, Tennessee (M.K.); Texas Children's Cancer Center, Baylor College of Medicine, Houston, Texas (M.E.H.).

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http://dx.doi.org/10.1093/neuonc/not163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3922508PMC
March 2014

A novel C19MC amplified cell line links Lin28/let-7 to mTOR signaling in embryonal tumor with multilayered rosettes.

Neuro Oncol 2014 Jan 4;16(1):62-71. Epub 2013 Dec 4.

Corresponding authors: Jennifer A. Chan, MD, Department of Pathology & Laboratory Medicine, University of Calgary, HRIC 2A25, 3330 Hospital Drive NW, Calgary, Alberta, Canada T2N 4N1. Annie Huang, MD, PhD, Division of Hematology-Oncology, Department of Pediatrics, The Hospital for Sick Children, TMDT, 11-401P, 101 College St., Toronto, Ontario, Canada M5G 1L7

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http://dx.doi.org/10.1093/neuonc/not162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3870842PMC
January 2014

Sustained response to weekly vinblastine in 2 children with pilomyxoid astrocytoma associated with diencephalic syndrome.

J Pediatr Hematol Oncol 2013 Mar;35(2):e53-6

Department of Pediatric Hematology Oncology and Bone Marrow Transplantation, Alberta Children's Hospital, ON, Canada.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MPH.0b013e3182707e67DOI Listing
March 2013

Early cisplatin induced ototoxicity profile may predict the need for hearing support in children with medulloblastoma.

Pediatr Blood Cancer 2013 Feb 21;60(2):287-92. Epub 2012 Sep 21.

Division of Pediatric Hematology Oncology and Bone Marrow Transplantation, Alberta Children's Hospital, Calgary, Canada.

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http://dx.doi.org/10.1002/pbc.24307DOI Listing
February 2013

Widespread osteonecrosis in children with leukemia revealed by whole-body MRI.

Clin Orthop Relat Res 2012 Dec 25;470(12):3587-95. Epub 2012 Sep 25.

Division of Pediatric Rheumatology, Department of Pediatrics, Alberta Children's Hospital and University of Calgary, 2888 Shaganappi Trail NW, Calgary, AB T3B 6A8, Canada.

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http://dx.doi.org/10.1007/s11999-012-2579-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492614PMC
December 2012

Spinal cord tumors in children under the age of 3 years: a retrospective Canadian review.

Childs Nerv Syst 2011 Jul 21;27(7):1089-94. Epub 2011 Jan 21.

Division of Oncology, Children's Hospital, London Health Sciences Center, London, Ontario, N6C 2V5, Canada.

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http://dx.doi.org/10.1007/s00381-011-1393-1DOI Listing
July 2011

Choroid plexus tumors in children less than 36 months: the Canadian Pediatric Brain Tumor Consortium (CPBTC) experience.

Childs Nerv Syst 2011 Feb 31;27(2):259-64. Epub 2010 Aug 31.

Pediatric Hematology Oncology and Bone marrow transplantation program, Alberta Children's Hospital, 2888 Shaganappi Trail NW, Calgary, AB, Canada.

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http://dx.doi.org/10.1007/s00381-010-1269-9DOI Listing
February 2011

Use of ifosfamide, carboplatin, and etoposide chemotherapy in choroid plexus carcinoma.

J Neurosurg Pediatr 2010 Jun;5(6):615-21

Department of Pediatric Oncology and Bone Marrow Transplantation, Alberta Children's Hospital, Calgary, Alberta, Canada.

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http://dx.doi.org/10.3171/2010.3.PEDS09354DOI Listing
June 2010

TP53 alterations determine clinical subgroups and survival of patients with choroid plexus tumors.

J Clin Oncol 2010 Apr 22;28(12):1995-2001. Epub 2010 Mar 22.

The Hospital for Sick Children, Division of Hematology/Oncology, 555 University Ave, Toronto, Ontario, M5G 1X8, Canada.

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http://dx.doi.org/10.1200/JCO.2009.26.8169DOI Listing
April 2010

Goldenhar phenotype in a child with distal 22q11.2 deletion and intracranial atypical teratoid rhabdoid tumor.

Am J Med Genet A 2009 Dec;149A(12):2855-9

Division of Pediatric Oncology and Bone Marrow Transplantation, Alberta Children's Hospital, 2888 Shaganappi Trail NW, Calgary, AB, Canada T3B 6A8.

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http://dx.doi.org/10.1002/ajmg.a.33119DOI Listing
December 2009

Medulloblastoma in children under the age of three years: a retrospective Canadian review.

J Neurooncol 2009 Aug 31;94(1):51-6. Epub 2009 Jan 31.

Division of Oncology, Children's Hospital of Eastern Ontario, 401 Smyth Road, Ottawa K1H 8L1, Ontario, Canada.

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http://dx.doi.org/10.1007/s11060-009-9799-2DOI Listing
August 2009

Current treatment approaches for infants with malignant central nervous system tumors.

Oncologist 2009 Apr 2;14(4):433-44. Epub 2009 Apr 2.

Alberta Children's Hospital and Department of Oncology and Pediatrics, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada.

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http://theoncologist.alphamedpress.org/cgi/doi/10.1634/theon
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http://dx.doi.org/10.1634/theoncologist.2008-0193DOI Listing
April 2009

Supratentorial primitive neuroectodermal tumors: a Canadian pediatric brain tumor consortium report.

J Neurooncol 2008 Jan 10;86(1):101-8. Epub 2007 Jul 10.

Division of Hematology/Oncology, Children's Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, ON, Canada, K1H 8L1.

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http://dx.doi.org/10.1007/s11060-007-9440-1DOI Listing
January 2008

Neuroradiological findings of bleomycin leakage in cystic craniopharyngioma. Report of three cases.

J Neurosurg 2007 Oct;107(4 Suppl):318-23

Pediatric Brain Tumor Program, Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.3171/PED-07/10/318DOI Listing
October 2007

Intracystic bleomycin therapy for craniopharyngioma in children: the Canadian experience.

Cancer 2007 May;109(10):2124-31

Division of Neurology and Oncology, British Columbia's Children's Hospital, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1002/cncr.22633DOI Listing
May 2007

Limited-field radiation for bifocal germinoma.

Int J Radiat Oncol Biol Phys 2006 Jun 10;65(2):486-92. Epub 2006 Mar 10.

Pediatric Brain Tumor Program, Hospital for Sick Children, Toronto, Ontario, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S036030160503079
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http://dx.doi.org/10.1016/j.ijrobp.2005.12.011DOI Listing
June 2006

Chromosomal insertion involving MLL in childhood acute myeloblastic leukemia (M4).

Cancer Genet Cytogenet 2004 Apr;150(2):153-5

INSERM Unité 524, Institut de Recherches sur le Cancer de Lille, 1 place de Verdun, 59000 Lille Cedex, France.

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http://dx.doi.org/10.1016/j.cancergencyto.2003.08.006DOI Listing
April 2004