Luciana Scotti

Luciana Scotti

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Luciana Scotti

Luciana Scotti

Publications by authors named "Luciana Scotti"

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100Publications

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Virtual Screening Studies for Discovery of Novel Inhibitors of Inflammatory Process Targets.

Curr Pharm Des 2018 ;24(14):1617-1638

Postgraduate Program in Natural and Synthetic Bioactive Products, Federal University of Paraíba, Joao Pessoa, Brazil.

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http://dx.doi.org/10.2174/1381612824666180403122410DOI Listing
October 2019

Exploring Secondary Metabolites Database of Apocynaceae, Menispermaceae, and Annonaceae to Select Potential Anti-HCV Compounds.

Curr Top Med Chem 2019 ;19(11):900-913

Post-Graduate Program in Natural Synthetic Bioactive Products, Federal University of Paraiba, Joao Pessoa, Brazil.

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http://dx.doi.org/10.2174/1568026619666190510094228DOI Listing
September 2019

Editorial: In Silico Studies in Drug Research Against Neurodegenerative Diseases.

Curr Neuropharmacol 2018;16(6):647-648

Federal University of Paraiba Campus I, 58051-900 Joao Pessoa-PB, Brazil.

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http://dx.doi.org/10.2174/1570159X1606180608103840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080093PMC
July 2019

Recent Theoretical Studies Concerning Important Tropical Infections.

Curr Med Chem 2019 Jul 11. Epub 2019 Jul 11.

Teaching and Research Management - University Hospital, Federal University of Paraíba, João Pessoa - PB. Brazil.

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http://dx.doi.org/10.2174/0929867326666190711121418DOI Listing
July 2019

Alcoholic monoterpenes found in essential oil of aromatic spices reduce allergic inflammation by the modulation of inflammatory cytokines.

Nat Prod Res 2019 Jun 2;33(12):1773-1777. Epub 2018 Feb 2.

a Laboratory of Neuroscience and Pharmacological Assays (LANEF), Department of Physiology , Federal University of Sergipe , Sergipe , Brazil.

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http://dx.doi.org/10.1080/14786419.2018.1434634DOI Listing
June 2019

Natural Bioactive Products with Antioxidant Properties Useful in Neurodegenerative Diseases.

Oxid Med Cell Longev 2019;2019:7151780. Epub 2019 May 9.

Postgraduate Program in Natural and Synthetic Bioactive Products, Federal University of Paraíba, João Pessoa, PB, Brazil.

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http://dx.doi.org/10.1155/2019/7151780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6532272PMC
May 2019

Nursing diagnosis risk for bleeding as an indicator of quality of care for patient safety.

Rev Gaucha Enferm 2019 29;40(spe):e20180322. Epub 2019 Apr 29.

Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Rio Grande do Sul, Brasil.

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http://dx.doi.org/10.1590/1983-1447.2019.20180322DOI Listing
April 2019

Docking of Natural Products against Neurodegenerative Diseases: General Concepts.

Comb Chem High Throughput Screen 2018 ;21(3):152-160

Postgraduate Program in Natural Products and Synthetic Bioactive- Federal University of Paraiba, 58051-970, Campus I, Joao Pessoa-PB, Brazil.

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http://www.eurekaselect.com/160440/article
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http://dx.doi.org/10.2174/1386207321666180313130314DOI Listing
March 2019

Editorial: In Silico Methodologies Applied to Drug Discovery.

Comb Chem High Throughput Screen 2018 ;21(3):150-151

Postgraduate Program in Natural Products and Synthetic Bioactive Federal University of Paraiba Campus I, 58051-900, Joao Pessoa- PB, Brazil.

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http://www.eurekaselect.com/161491/article
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http://dx.doi.org/10.2174/138620732103180423125817DOI Listing
March 2019

In Silico and Molecular Docking Studies That Address Viral (Std) Transmission Points.

Curr Protein Pept Sci 2019 Mar 11. Epub 2019 Mar 11.

Program of Natural and Synthetic Bioactive Products (PgPNSB), Health Sciences Center, Federal University of Paraíba, João Pessoa-PB. Brazil.

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http://dx.doi.org/10.2174/1389203720666190311142747DOI Listing
March 2019

Editorial: Multi-Target in Computer-Aided Drug Design Studies.

Curr Drug Targets 2017 ;18(5):498-499

Federal University of Paraíba Department of Engineering and the Environment Campus IV; 58297-000, Rio Tinto-PB, Brazil.

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http://dx.doi.org/10.2174/138945011805170224223532DOI Listing
February 2019

Computational Approaches in Multitarget Drug Discovery.

Methods Mol Biol 2018 ;1800:327-345

Postgraduate Program in Natural Products and Synthetic Bioactive, Federal University of Paraíba, João Pessoa, PB, Brazil.

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http://dx.doi.org/10.1007/978-1-4939-7899-1_16DOI Listing
February 2019

Computational Studies Applied to Flavonoids against Alzheimer's and Parkinson's Diseases.

Oxid Med Cell Longev 2018 30;2018:7912765. Epub 2018 Dec 30.

Postgraduate Program in Natural and Synthetic Bioactive Products, Federal University of Paraíba, João Pessoa, PB, Brazil.

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http://dx.doi.org/10.1155/2018/7912765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332933PMC
February 2019

Predictive Computational Tools for Assessment of Ecotoxicological Activity of Organic Micropollutants in Various Water Sources in Brazil.

Mol Inform 2019 Feb 6. Epub 2019 Feb 6.

Post-Graduate Program in Natural and Synthetic Bioactive Products, Federal University of Paraíba, 58051-900, João Pessoa, PB, Brazil.

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http://dx.doi.org/10.1002/minf.201800156DOI Listing
February 2019

Perspectives on Infectious Diseases: Progress and Therapeutics.

Curr Top Med Chem 2018;18(9):748-749

Cheminformatics Laboratory- Postgraduate Program in Natural Products and Synthetic Bioactive, Federal University of Paraiba Campus I, 58051-900, Joao Pessoa-PB, Brazil.

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http://dx.doi.org/10.2174/156802661809180723122350DOI Listing
January 2019

Computational Studies in Drug Design Against Cancer.

Anticancer Agents Med Chem 2019 ;19(5):587-591

Federal University of Paraiba, Campus I; 58051-970, Joao Pessoa, PB, Brazil.

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http://dx.doi.org/10.2174/1871520618666180911125700DOI Listing
January 2019

Virtual Screening of Natural Products to Select Compounds with Potential Anticancer Activity.

Anticancer Agents Med Chem 2019 ;19(2):154-171

Program of Natural and Synthetic Bioactive Products (PgPNSB), Health Sciences Center, Federal University of Paraíba, 58051-900, João Pessoa-PB, Brazil.

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http://dx.doi.org/10.2174/1871520618666181119110934DOI Listing
January 2019

Multi-Target Drugs Against Metabolic Disorders.

Endocr Metab Immune Disord Drug Targets 2019 ;19(4):402-418

Postgraduate Program in Natural and Synthetic Bioactive Products, Federal University of Paraiba, Joao Pessoa, PB, Brazil.

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http://dx.doi.org/10.2174/1871530319666181217123357DOI Listing
January 2019

Multi-Target Drugs Against Metabolic Disorders.

Endocr Metab Immune Disord Drug Targets 2019 ;19(4):389-390

Federal University of Paraiba, Health Sci. Center, 50670-910, Joao Pessoa, PB, Brazil.

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http://dx.doi.org/10.2174/187153031904190506102405DOI Listing
January 2019

Editorial: Identification of Lead Compounds Using Metabolomic Analysis in Drug Discovery.

Comb Chem High Throughput Screen 2017 ;20(3):184-185

Department of Chemistry, Universidad Militar Nueva Granada, Campus Nueva Granada, Cajica, Cundinamarca, Colombia, United States.

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http://dx.doi.org/10.2174/138620732003170607162843DOI Listing
December 2018

Dengue Virus Inhibition Targets: A Review and Docking Study.

Curr Top Med Chem 2018 ;18(18):1522-1530

University of Western Sao Paulo (UNOESTE), Presidente Prudente, Sao Paulo, Brazil.

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http://dx.doi.org/10.2174/1568026618666181025111605DOI Listing
December 2018

Recent Advancement against Neglected Diseases.

Curr Top Med Chem 2018 ;18(18):1520-1521

Department of Biochemistry/Bioinformatics Institute of Science GITAM University, Visakhapatnam, A.P, India.

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http://dx.doi.org/10.2174/156802661818181119142905DOI Listing
December 2018

Computer-aided Drug Design Applied to Parkinson Targets.

Curr Neuropharmacol 2018 ;16(6):865-880

Federal University of Paraiba, Campus I, Joao Pessoa-PB, Brazil.

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http://dx.doi.org/10.2174/1570159X15666171128145423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080092PMC
October 2018

Editorial: Theoretical Studies of the Metabolism in Drug Discovery.

Curr Drug Metab 2017;18(6):498-499

Federal University of Paraíba Campus I, 58051-900, João Pessoa-PB, Brazil.

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http://dx.doi.org/10.2174/138920021806170721113611DOI Listing
September 2018

Editorial: Natural Product Inhibitors of Enzymatic Targets in Anticancer Drug Discovery - Part I.

Curr Protein Pept Sci 2018;19(3):236-237

Federal University of Paraiba Campus I, 58051-900 Joao Pessoa-PB. Brazil.

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http://dx.doi.org/10.2174/138920371903180104105702DOI Listing
September 2018

Editorial (Thematic Issue: Medicinal Chemistry Applied to Natural Products in Neglected Drug Discovery).

Comb Chem High Throughput Screen 2016 ;19(7):514-5

Professor of Organic and Medicinal Chemistry Head of the Laboratory of Synthesis and Drug Delivery State University of Paraiba João Pessoa-PB Brazil.

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http://dx.doi.org/10.2174/138620731907160712181908DOI Listing
August 2018

Multi-Target Antitubercular Drugs.

Curr Top Med Chem 2018 ;18(9):750-758

Cheminformatics Laboratory, Postgraduate Program in Natural Products and Synthetic Bioactive, Federal University of Paraiba, Campus I, 58051-900, Joao Pessoa-PB, Brazil.

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http://dx.doi.org/10.2174/1568026618666180528124414DOI Listing
August 2018

Editorial (Thematic Issue: Hybrid Compounds as Multitarget Agents in Medicinal Chemistry - Part II).

Curr Top Med Chem 2017 ;17(9):957-958

Federal University of Paraíba Campus I, 58051-900, João Pessoa-PB Brazil. Brazil.

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http://dx.doi.org/10.2174/156802661709170213205211DOI Listing
May 2018

Editorial: Hybrid Compounds as Multitarget Agents in Medicinal Chemistry - Part I.

Curr Top Med Chem 2017 ;17(8):843-844

Federal University of Paraíba Campus I, 58051-900, João Pessoa-PB. Brazil.

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http://dx.doi.org/10.2174/156802661708170126200430DOI Listing
May 2018

New Therapeutic Targets and Drugs for the Treatment of Asthma.

Mini Rev Med Chem 2018 ;18(8):684-696

Postgraduate Program in Natural Products and Synthetic Bioactive, Federal University of Paraiba, Joao Pessoa - PB, Brazil.

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http://dx.doi.org/10.2174/1389557517666170927145011DOI Listing
May 2018

Predictive ecotoxicity of MoA 1 of organic chemicals using in silico approaches.

Ecotoxicol Environ Saf 2018 May 8;153:151-159. Epub 2018 Feb 8.

Post-Graduate Program in Natural and Synthetic Bioactive Products, Federal University of Paraíba, 58051-900 João Pessoa, PB, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.ecoenv.2018.01.054DOI Listing
May 2018

Momordicacharantia: A New Strategic Vision to Improve the Therapy of Endoplasmic Reticulum Stress.

Curr Pharm Des 2017 ;23(16):2333-2343

Health Sciences Center, Federal University of Paraíba, Campus I, 58051-970, João Pessoa-PB. Brazil.

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http://dx.doi.org/10.2174/1381612823666170124141104DOI Listing
April 2018

Editorial: Research and Selection of Multitarget Compounds in Medicinal Chemistry.

Curr Med Chem 2017;24(16):1627-1628

Federal University of Paraíba Campus I, 58051-900, João Pessoa-PB, Brazil.

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http://dx.doi.org/10.2174/092986732416170704114736DOI Listing
April 2018

In Silico Studies Designed to Select Sesquiterpene Lactones with Potential Antichagasic Activity from an In-House Asteraceae Database.

ChemMedChem 2018 03 6;13(6):634-645. Epub 2018 Feb 6.

Post-Graduate Program in Natural and Synthetic Bioactive Products, Federal University of Paraíba, Cidade Universitária - Castelo Branco III, João Pessoa, PB, Brazil.

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http://dx.doi.org/10.1002/cmdc.201700743DOI Listing
March 2018

Flow Cytometry in Detection of Fetal Red Blood Cells and Maternal F Cells to Identify Fetomaternal Hemorrhage.

Fetal Pediatr Pathol 2016 5;35(6):385-391. Epub 2016 Aug 5.

e Department of Obstetrics and Gynecology , Hospital de Clinicas de Porto Alegre , Porto Alegre , Brazil.

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http://dx.doi.org/10.1080/15513815.2016.1209260DOI Listing
February 2018

Editorial; Natural Product Inhibitors of Enzymatic Targets in Anticancer Drug Discovery - Part II.

Curr Protein Pept Sci 2018 Feb;19(4):342

Federal University of Paraíba Campus I, 58051-900 João Pessoa-PB, Brazil.

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http://dx.doi.org/10.2174/138920371904180213111017DOI Listing
February 2018

Editorial (Thematic Issue: Polypharmacology in Drug Discovery).

Curr Pharm Des 2016;22(21):3071-2

Federal University of Paraíba Campus I, 58051-900 João Pessoa-PB PB, Brazil.

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January 2018

SistematX, an Online Web-Based Cheminformatics Tool for Data Management of Secondary Metabolites.

Molecules 2018 Jan 3;23(1). Epub 2018 Jan 3.

AsterBioChem Research Team, Laboratory of Pharmacognosy, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo (USP), Av. do Café s/n, Ribeirão Preto 14040-903, SP, Brazil.

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http://dx.doi.org/10.3390/molecules23010103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017134PMC
January 2018

In Silico Studies Revealed Multiple Neurological Targets for the Antidepressant Molecule Ursolic Acid.

Curr Neuropharmacol 2017 Nov;15(8):1100-1106

Division of Biological Sciences and Engineering, Netaji Subhas Institute of Technology, Sector-3, Dwarka, New Delhi, 110078, India.

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http://dx.doi.org/10.2174/1570159X14666161229115508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725542PMC
November 2017

Docking Studies for Multi-Target Drugs.

Curr Drug Targets 2017 ;18(5):592-604

Federal University of Paraíba, Campus I, Joao Pessoa-PB, Brazil.

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http://dx.doi.org/10.2174/1389450116666150825111818DOI Listing
September 2017

Secondary Metabolites from Cissampelos, A Possible Source for New Leads with Anti-Inflammatory Activity.

Curr Med Chem 2017 ;24(16):1629-1644

Postgraduate Program in Natural and Synthetic Bioactive Products, Federal University of Paraíba, João Pessoa - PB, Brazil.

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http://dx.doi.org/10.2174/0929867323666161227123411DOI Listing
September 2017

Natural Products as a Source for Antileishmanial and Antitrypanosomal Agents.

Comb Chem High Throughput Screen 2016 ;19(7):537-53

Health Sciences Center, Federal University of Paraiba, Campus I, 58051-970, João Pessoa, PB, Brazil.

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http://dx.doi.org/10.2174/1386207319666160506123921DOI Listing
July 2017

Recent Advancement in Natural Hyaluronidase Inhibitors.

Curr Top Med Chem 2016 ;16(23):2525-31

Health Sciences Center, Federal University of Paraíba, Campus I, 58051-970, João Pessoa-PB, Brazil.

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http://dx.doi.org/10.2174/1568026616666160414123857DOI Listing
February 2017

Editorial (Thematic Issue: Natural Leads in Drug Discovery against Metabolic Disorders and their Related Infectious Diseases).

Curr Top Med Chem 2016 ;16(23):2523-4

Federal University of Paraíba Department of Engineering and the Environment Campus IV; 58297-000, Rio Tinto PB, Brazil.

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http://dx.doi.org/10.2174/1568026616999160510121418DOI Listing
February 2017

Perspectives in Medicinal Chemistry.

Curr Top Med Chem 2016 ;16(25):2725-6

Federal University of Paraíba, Health Center, 50670-910, João Pessoa, PB, Brazil.

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http://dx.doi.org/10.2174/156802661625160816180839DOI Listing
February 2017

Computer-Aided Drug Design Using Sesquiterpene Lactones as Sources of New Structures with Potential Activity against Infectious Neglected Diseases.

Molecules 2017 Jan 3;22(1). Epub 2017 Jan 3.

Post-Graduate Program in Natural and Synthetic Bioactive Products, Federal University of Paraíba, 58051-900 João Pessoa, PB, Brazil.

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http://dx.doi.org/10.3390/molecules22010079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155652PMC
January 2017

Enzymatic Studies in Medicinal Chemistry of Neglected Diseases.

Curr Protein Pept Sci 2016 ;17(3):210-2

Federal University of Paraíba Department of Engineering and the Environment Campus IV; 58297-000 Rio Tinto, PB Brazil.

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December 2016

Enzymatic Targets in Trypanosoma brucei.

Curr Protein Pept Sci 2016 ;17(3):243-59

Health Sciences Center, Federal University of Paraiba, Campus I, 58051-970, João Pessoa, PB, Brazil.

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December 2016

Antileishmanial activity of new thiophene-indole hybrids: Design, synthesis, biological and cytotoxic evaluation, and chemometric studies.

Bioorg Med Chem 2016 09 26;24(18):3972-3977. Epub 2016 Apr 26.

Departamento de Biologia Molecular, Centro de Ciências Exatas e da Natureza, Universidade Federal da Paraíba, Campus I, Castelo Branco, João Pessoa, Paraíba CEP 58059-900, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2016.04.057DOI Listing
September 2016

Determination of reference ranges for immature platelet and reticulocyte fractions and reticulocyte hemoglobin equivalent.

Rev Bras Hematol Hemoter 2016 Oct - Dec;38(4):310-313. Epub 2016 Aug 6.

Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, RS, Brazil.

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http://dx.doi.org/10.1016/j.bjhh.2016.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119661PMC
August 2016

Artificial Neural Network Methods Applied to Drug Discovery for Neglected Diseases.

Comb Chem High Throughput Screen 2015 ;18(8):819-29

Health Sciences Center, Federal University of Paraiba, Campus I, 58051-970, João Pessoa, PB, Brazil.

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http://dx.doi.org/10.2174/1386207318666150803141219DOI Listing
June 2016

Editorial: Chemometrics in Drug Discovery.

Comb Chem High Throughput Screen 2015 ;18(8):702-3

Federal University of Paraíba, Campus I, João Pessoa, PB, Brazil.

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http://dx.doi.org/10.2174/138620731808150904121214DOI Listing
June 2016

Computer Aided Drug Design Studies in the Discovery of Secondary Metabolites Targeted Against Age-Related Neurodegenerative Diseases.

Curr Top Med Chem 2015 ;15(21):2239-52

Federal University of Paraiba, Health Sciences Center, Campus I, 58051-970, Joao Pessoa, PB, Brazil.

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http://dx.doi.org/10.2174/1568026615666150610143510DOI Listing
May 2016

Multi-Target Drugs for Neglected Diseases.

Curr Pharm Des 2016 05;22(21):3135-63

Health Sciences Center, Federal University of Paraíba, Campus I, 58051-970, João Pessoa, PB, Brazil.

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http://dx.doi.org/10.2174/1381612822666160224142552DOI Listing
May 2016

Perspectives in Medicinal Chemistry.

Curr Top Med Chem 2016 May 10. Epub 2016 May 10.

Federal University of Paraíba, Department of Engineering and the Environment, Campus IV; 58297-000, Rio Tinto, PB, Brazil.

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May 2016

Modulation of Drug Resistance in Staphylococcus aureus with Coumarin Derivatives.

Scientifica (Cairo) 2016 19;2016:6894758. Epub 2016 Apr 19.

Post-Graduate Program in Natural and Synthetic Bioactive Products, Federal University of Paraíba, 58051-900 João Pessoa, PB, Brazil; Laboratory of Synthesis and Drug Delivery, Biological Science Department, State University of Paraíba, 58071-160 João Pessoa, PB, Brazil.

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http://dx.doi.org/10.1155/2016/6894758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856757PMC
May 2016

Editorial: Natural Leads in Drug Discovery against Metabolic Disorders and their Related Infectious Diseases.

Curr Top Med Chem 2016 May 23. Epub 2016 May 23.

Federal University of Paraíba Department of Engineering and the Environment Campus IV; 58297-000, Rio Tinto PB, Brazil.

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May 2016

Reference interval determination of hemoglobin fractions in umbilical cord and placental blood by capillary electrophoresis.

Clin Biochem 2016 Apr 2;49(6):521-523. Epub 2015 Dec 2.

Pathology Clinic Departament, Hospital de Clínicas de Porto Alegre (HCPA), Rua Ramiro Barcelos, 2350, 90035-003 Porto Alegre, Brazil.

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http://dx.doi.org/10.1016/j.clinbiochem.2015.11.019DOI Listing
April 2016

Editorial: Polypharmacology in Drug Discovery.

Curr Pharm Des 2016 Apr 5. Epub 2016 Apr 5.

Federal University of Paraíba Department of Engineering and the Environment Campus IV; 58297-000, Rio Tinto PB, Brazil.

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April 2016

Editorial: medicinal chemistry studies of neglected diseases.

Mini Rev Med Chem 2015 ;15(3):180-1

Federal University of Paraiba Campus I, 58051-900 Joao Pessoa-PB Brazil.

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http://dx.doi.org/10.2174/138955751503150312115541DOI Listing
December 2015

2-Amino-thiophene derivatives present antileishmanial activity mediated by apoptosis and immunomodulation in vitro.

Eur J Med Chem 2015 Dec 17;106:1-14. Epub 2015 Oct 17.

Programa de Pós-Graduação em Biologia Molecular, Centro de Ciências Exatas e da Natureza, Universidade Federal da Paraíba, 58051-970, João Pessoa, PB, Brazil; Departamento de Biologia Molecular, Centro de Ciências Exatas e da Natureza, Universidade Federal da Paraíba, João Pessoa, Paraíba CEP, 58059-900, Brazil. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2015.10.011DOI Listing
December 2015

Chemometric studies on potential larvicidal compounds against Aedes aegypti.

Med Chem 2014 Mar;10(2):201-10

State University of Paraíba, Biological Science Department, Laboratory of Synthesis and Drug Delivery, 58070-450, Joao Pessoa, PB, Brazil.

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March 2014

Quantitative structure-sorption relationships of pesticides used in the sugarcane industry in the northern coastal area of Paraíba State, Brazil.

Altern Lab Anim 2014 Mar;42(1):81-90

Centre for Applied Sciences and Education, Federal University of Paraíba, Campus IV, Rio Tinto, PB, Brazil.

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http://dx.doi.org/10.1177/026119291404200111DOI Listing
March 2014

SAR, QSAR and docking of anticancer flavonoids and variants: a review.

Curr Top Med Chem 2012 ;12(24):2785-809

Federal University of Paraíba, Centre for Biotechnology, 50670-910, João Pessoa, PB, Brazil.

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http://dx.doi.org/10.2174/1568026611212240007DOI Listing
September 2013