Publications by authors named "Lucia Moiola"

89Publications

In vivo gradients of thalamic damage in paediatric multiple sclerosis: a window into pathology.

Brain 2020 Nov 21. Epub 2020 Nov 21.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.

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November 2020

COVID-19 in cladribine-treated relapsing-remitting multiple sclerosis patients: a monocentric experience.

J Neurol 2020 Nov 20. Epub 2020 Nov 20.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.

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November 2020

Inferring Multiple Sclerosis Stages from the Blood Transcriptome via Machine Learning.

Cell Rep Med 2020 Jul 21;1(4):100053. Epub 2020 Jul 21.

Institute of Experimental Neurology and Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.

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July 2020

Occurrence and microstructural features of slowly expanding lesions on fingolimod or natalizumab treatment in multiple sclerosis.

Mult Scler 2020 Nov 13:1352458520969105. Epub 2020 Nov 13.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy/Neurology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy/Vita-Salute San Raffaele University, Milan, Italy.

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November 2020

Newly approved agents for relapsing remitting multiple sclerosis: how real-world evidence compares with randomized clinical trials?

Expert Rev Neurother 2021 Jan 10;21(1):21-34. Epub 2020 Oct 10.

Institute of Experimental Neurology of San Raffaele Hospital , Milan, Italy.

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January 2021

Early evidence of disease activity during fingolimod predicts medium-term inefficacy in relapsing-remitting multiple sclerosis.

Mult Scler 2020 Sep 25:1352458520961690. Epub 2020 Sep 25.

Neurology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy/Neurorehabilitation Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy/Laboratory of Human Genetics of Neurological Disorders, Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.

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September 2020

Allergy and dimethyl fumarate treatment in a patient with multiple sclerosis.

J Neurol Sci 2020 11 22;418:117104. Epub 2020 Aug 22.

Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Scientific Institute, Milan, Italy.

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November 2020

Neuromyelitis optica and myotonic dystrophy type 2: a rare association with diagnostic implications.

J Neurol 2020 Sep 9;267(9):2744-2746. Epub 2020 Jul 9.

Neurology Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.

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September 2020

Prevention and management of adverse effects of disease modifying treatments in multiple sclerosis.

Curr Opin Neurol 2020 06;33(3):286-294

Neuroimmunology Section, Department of Neurology, University of Rostock, Rostock, Germany.

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June 2020

Two-year regional grey and white matter volume changes with natalizumab and fingolimod.

J Neurol Neurosurg Psychiatry 2020 05 28;91(5):493-502. Epub 2020 Feb 28.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy

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May 2020

Changes in cortical motor outputs after a motor relapse of multiple sclerosis.

Mult Scler J Exp Transl Clin 2019 Jul-Sep;5(3):2055217319866480. Epub 2019 Sep 25.

Department of Neurorehabilitation and Department of Clinical Neurophysiology, Hospital San Raffaele, Milan, Italy.

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September 2019

Multiple sclerosis associated with pembrolizumab in a patient with non-small cell lung cancer.

J Neurol 2019 12 4;266(12):3163-3166. Epub 2019 Oct 4.

Neurology Unit, IRCCS San Raffaele Scientific Institute, Via Olgettina 60, 20132, Milan, Italy.

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December 2019

Loss of Circulating CD8+ CD161 T Cells in Primary Progressive Multiple Sclerosis.

Front Immunol 2019 14;10:1922. Epub 2019 Aug 14.

Division of Neuroscience, Institute of Experimental Neurology, San Raffaele Scientific Institute, Milan, Italy.

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October 2020

Effects of Natalizumab and Fingolimod on Clinical, Cognitive, and Magnetic Resonance Imaging Measures in Multiple Sclerosis.

Neurotherapeutics 2020 01;17(1):208-217

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele Scientific Institute, Via Olgettina, 60, Milan, 20132, Italy.

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January 2020

Subclinical neurodegeneration in multiple sclerosis and neuromyelitis optica spectrum disorder revealed by optical coherence tomography.

Mult Scler 2020 09 8;26(10):1197-1206. Epub 2019 Aug 8.

Department of Neurorehabilitation and Department of Clinical Neurophysiology, Hospital San Raffaele, Milan, Italy/ INSPE, Institute of Experimental Neurology (INSPE), San Raffaele Scientific Institute, Milan, Italy/ University Vita-Salute San Raffaele, Milan, Italy.

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September 2020

Performance of SLE responder index and lupus low disease activity state in real life: A prospective cohort study.

Int J Rheum Dis 2019 Sep 5;22(9):1752-1761. Epub 2019 Aug 5.

Unit of Immunology, Rheumatology, Allergy and Rare Diseases, IRCCS Ospedale San Raffaele, Milan, Italy.

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September 2019

Pharmacokinetics and pharmacodynamics of natalizumab in pediatric patients with RRMS.

Neurol Neuroimmunol Neuroinflamm 2019 09 1;6(5):e591. Epub 2019 Jul 1.

Multiple Sclerosis Study Center (A.G.), ASST Valle Olona, Gallarate Hospital (VA); Department of Neurology (G.C., L.M.), Institute of Experimental Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan; Department of Neurology (L.M.G.), Fondazione Istituto G. Giglio, Cefalù; Department of Neurology (C.P.), "La Sapienza" University, Rome; Biogen Italia (S.F.), Milan; and Department of Neuroscience DNS, Multiple Sclerosis Centre (P.G.), Università degli Studi di Padova, Italy.

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September 2019

Caesarean section and infant formula feeding are associated with an earlier age of onset of multiple sclerosis.

Mult Scler Relat Disord 2019 Aug 21;33:75-77. Epub 2019 May 21.

Department of Neurology, San Raffaele Hospital, via Olgettina 48, 20132 Milan, Italy. Electronic address:

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August 2019

Dynamic gray matter volume changes in pediatric multiple sclerosis: A 3.5 year MRI study.

Neurology 2019 04 13;92(15):e1709-e1723. Epub 2019 Mar 13.

From the Neuroimaging Research Unit (E.D.M., A.M., M.F., M.A.R.) and Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience (E.D.M., L.M., M.F., M.A.R.), San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan; Multiple Sclerosis Center (A.G.), Ospedale di Gallarate; Pediatric Neurology Unit (P.V.), V. Buzzi Children's Hospital, Milan; and Biomedical and Clinical Science Department (P.V.), University of Milan, Italy.

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April 2019

Prognostic value of serum neurofilaments in patients with clinically isolated syndromes.

Neurology 2019 02 11;92(7):e733-e741. Epub 2019 Jan 11.

From the Department of Neurology (G.D.C., V.M., F.S., L.M., B.C., M.R., G.C.), Experimental Neurophysiology Research Unit (L.L.), and Neuroimmunology Research Unit (R.F.), San Raffaele Hospital, Milan, Italy.

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February 2019

Severe disease activity in a patient with multiple sclerosis after daclizumab discontinuation.

Mult Scler Relat Disord 2019 Feb 1;28:57-59. Epub 2018 Dec 1.

Department of Neurology, San Raffaele Hospital, via Olgettina 48, 20132 Milan, Italy.

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February 2019

Pregnancy decision-making in women with multiple sclerosis treated with natalizumab: I: Fetal risks.

Neurology 2018 03 7;90(10):e823-e831. Epub 2018 Feb 7.

From IRCCS Don Gnocchi Foundation (E.P.), Florence; Multiple Sclerosis Study Center (P.A., A.G., M.Z.), ASST Valle Olona, Gallarate Hospital (VA); Scientific Institute University Vita-Salute San Raffaele (L.M., V.M., G.C.), Milan; Department of Neurosciences, Reproductive and Odontostomatological Sciences (R.L., V.B.M.), Federico II University of Naples; Department of Neurosciences (F.R., P.G.), Multiple Sclerosis Centre-Veneto Region (CeSMuV), University Hospital of Padova; Department of Neurology (C.T., D.P., M.T.), University of Bari; Department of Neurology and Psychiatry (C.P., L.D.G.), "La Sapienza" University, Rome; Department of Neurology (P.C.), University of Torino; Department of Medical Sciences and Public Health (E.C., M.G.M.), University of Cagliari; Department of Neurology (F.P.), University of Catania; Department of Neurology (C.S.), ASL3 Genovese; Multiple Sclerosis Center (P.B.), IRCCS Neuromed, Pozzilli; Department of Neurology (A.U., A.L.), University of Genova; and Department of NEUROFARBA (L.P., M.G., M.P.A.), University of Florence, Italy.

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March 2018

Pregnancy decision-making in women with multiple sclerosis treated with natalizumab: II: Maternal risks.

Neurology 2018 03 7;90(10):e832-e839. Epub 2018 Feb 7.

From IRCCS Don Gnocchi Foundation (E.P.), Florence; Scientific Institute University Vita-Salute San Raffaele (L.M., V.M., G.C.), Milan; Multiple Sclerosis Study Center (P.A., A.G., M.Z.), ASST Valle Olona, Gallarate Hospital (VA); Department of Neurosciences, Reproductive and Odontostomatological Sciences (R.L., V.B.M.), Federico II University of Naples; Department of Neurosciences (F.R., P.G.), Multiple Sclerosis Centre-Veneto Region (CeSMuV), University Hospital of Padova; Department of Neurology (C.T., D.P., M.T.), University of Bari; Department of Neurology and Psychiatry (C.P., L.D.G.), "La Sapienza" University, Rome; Department of Neurology (P.C.), University of Torino; Department of Medical Sciences and Public Health (E.C., M.G.M.), University of Cagliari; Department of Neurology (C.S.), ASL3 Genovese; Department of Neurology (A.U., A.L.), University of Genova; and Department of NEUROFARBA (L.P., M.G., M.P.A.), University of Florence, Italy.

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March 2018

Necrotic-hemorrhagic myelitis: A rare malignant variant of parainfectious acute disseminated encephalomyelitis in childhood.

J Neurol Sci 2018 01 23;384:58-60. Epub 2017 Nov 23.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy; Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy. Electronic address:

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January 2018

Smart watch, smarter EDSS: Improving disability assessment in multiple sclerosis clinical practice.

J Neurol Sci 2017 Dec 27;383:166-168. Epub 2017 Oct 27.

Department of Neurology, San Raffaele Hospital, Milan, Italy. Electronic address:

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December 2017

No evidence of disease activity is associated with reduced rate of axonal retinal atrophy in MS.

Neurology 2017 Dec 15;89(24):2469-2475. Epub 2017 Nov 15.

From the Neurological Department and Institute of Experimental Neurology (INSPE) (M.P., S.G., G.D.M., S.M., L.M., V.M., G.C., L.L.), Scientific Institute, Hospital San Raffaele; and University Vita-Salute San Raffaele (M.P., S.G., G.C., L.L.), Milan, Italy.

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December 2017

MRI substrates of sustained attention system and cognitive impairment in pediatric MS patients.

Neurology 2017 Sep 18;89(12):1265-1273. Epub 2017 Aug 18.

From the Neuroimaging Research Unit (E.D.M., E.P., M.F., M.A.R.) and Department of Neurology (E.D.M., L.M., A. Fiorino, G.C., M.F., M.A.R.), Institute of Experimental Neurology, Division of Neuroscience, and Department of Neuroradiology (A. Falini), San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan; Multiple Sclerosis Center (A.G., L.P.), Ospedale di Gallarate; Department of Child Neurology and Psychiatry (P.V., M.C.P.), C. Mondino National Neurological Institute, Brain and Behaviour Department, University of Pavia; Multiple Sclerosis Center (R.C.), Spedali Civili of Brescia; and Department NEUROFARBA (M.P.A.), Section Neurosciences, University of Florence, Italy.

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September 2017

Dysregulation of MS risk genes and pathways at distinct stages of disease.

Neurol Neuroimmunol Neuroinflamm 2017 May 16;4(3):e337. Epub 2017 Mar 16.

Institute of Experimental Neurology (INSpe) (S.S., M.D.D., A.R., R.M., E.B., M. Romeo, F.S., G.D.C., M. Rodegher, M. Radaelli, L.M., G.M., R.F., V.M., G.C., C.F.), Division of Neuroscience, San Raffaele Scientific Institute, Milan; University Vita-Salute San Raffaele (S.S., E.B., G.C.), Milan; and Laboratory of Functional Genomics (D.C., E.M.), Institute for Cancer Research and Treatment (IRCC), University of Turin Medical School, Candiolo, Italy.

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May 2017

Moyamoya disease mimicking the first attack of multiple sclerosis.

J Neurol 2017 May 17;264(5):1005-1007. Epub 2017 Mar 17.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina, 60, 20132, Milan, Italy.

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May 2017

Clinical deterioration due to co-occurrence of multiple sclerosis and glioblastoma: report of two cases.

Neurol Sci 2017 Feb 11;38(2):361-364. Epub 2016 Nov 11.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Via Olgettina, 60, 20132, Milan, Italy.

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February 2017

Natalizumab versus fingolimod in patients with relapsing-remitting multiple sclerosis non-responding to first-line injectable therapies.

Mult Scler 2016 09 26;22(10):1315-26. Epub 2016 May 26.

Department of Neurology, San Raffaele Hospital, Milan, Italy/Division of Neuroscience, Department of Neurology, Institute of Experimental Neurology, San Raffaele Scientific Institute, Milan, Italy.

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September 2016

The Communication of Multiple Sclerosis Diagnosis: The Patients' Perspective.

Mult Scler Int 2015 15;2015:353828. Epub 2015 Dec 15.

Institute of Experimental Neurology, Division of Neuroscience, Scientific Institute and University San Raffaele Hospital, Via Olgettina 48, 20132 Milan, Italy.

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January 2016

Myeloid cells as target of fingolimod action in multiple sclerosis.

Neurol Neuroimmunol Neuroinflamm 2015 Dec 4;2(6):e157. Epub 2015 Nov 4.

Institute of Experimental Neurology (INSpe), Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy.

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December 2015

Regional hippocampal involvement and cognitive impairment in pediatric multiple sclerosis.

Mult Scler 2016 Apr 18;22(5):628-40. Epub 2015 Aug 18.

Neuroimaging Research Unit, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Italy/Department of Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Italy

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April 2016

Impact of MS genetic loci on familial aggregation, clinical phenotype, and disease prediction.

Neurol Neuroimmunol Neuroinflamm 2015 Aug 9;2(4):e129. Epub 2015 Jul 9.

Department of Neurology (F.E., C.G., L.F., M.P., M. Radaelli, B.C., L.M., M. Rodegher, V.M., G.C., F.M.B.) and Laboratory of Genetics of Neurological Complex Disorders (F.E., C.G., M.S., F.C., L.F., E.M., S.S., M.P., G.C., F.M.B.), Institute of Experimental Neurology, Division of Neuroscience, and Center for Translational Genomics and Bioinformatics (E.S.), San Raffaele Scientific Institute, Milan, Italy.

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August 2015

Abnormal cerebellar functional MRI connectivity in patients with paediatric multiple sclerosis.

Mult Scler 2016 Mar 10;22(3):292-301. Epub 2015 Jul 10.

Neuroimaging Research Unit, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy

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March 2016

Cognitive impairment in paediatric multiple sclerosis patients is not related to cortical lesions.

Mult Scler 2015 Jun 12;21(7):956-9. Epub 2014 Nov 12.

Neuroimaging Research Unit, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy/Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy

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June 2015

Recurrence of disease activity after repeated Natalizumab withdrawals.

Neurol Sci 2015 Mar 24;36(3):465-7. Epub 2014 Sep 24.

Department of Neurology-Institute of Experimental Neurology, Scientific Institute San Raffaele, Via Olgettina, 48 20132, Milan, Italy,

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March 2015

Neuropsychological features in childhood and juvenile multiple sclerosis: five-year follow-up.

Neurology 2014 Oct 12;83(16):1432-8. Epub 2014 Sep 12.

From the Department of NEUROFARBA (M.P.A., B.G., B.H., C.N., S.L., E.P.), University of Florence; MS Centre (A.G., M.R.), Hospital of Gallarate; Neurological Department (L.M., M.F., V.M., G.C.), IRCCS Hospital San Raffaele, Milano; Department of Neuroscience and Sense Organs (R.G.V., M.T.), University of Bari; Multiple Sclerosis Centre (F.P., S.C.), University Polyclinic Hospital G. Rodolico, Catania; and Department of Neurological Sciences (C.P., V.B.), La Sapienza University, Rome, Italy.

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October 2014

Posterior brain damage and cognitive impairment in pediatric multiple sclerosis.

Neurology 2014 Apr 19;82(15):1314-21. Epub 2014 Mar 19.

From the Neuroimaging Research Unit (M.A.R., M.A., M.F.), Department of Neurology, Institute of Experimental Neurology, Division of Neuroscience (M.A.R., M.A., L.M., A. Fiorino, G.C., M.F.), and Department of Neurology (M.P.A., E.P.), University of Florence; the Multiple Sclerosis Center (A.G., L.P.), Ospedale di Gallarate; Fondazione "Istituto Neurologico Casimiro Mondino" (P.V., M.C.P.), Pavia; Multiple Sclerosis Center (R.C.), Spedali Civili of Brescia, Italy; Department of Cardiovascular Sciences (M.A.H.), University of Leicester, UK; and the Department of Neuroradiology (A. Falini), San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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April 2014

Intranetwork and internetwork functional connectivity abnormalities in pediatric multiple sclerosis.

Hum Brain Mapp 2014 Aug 7;35(8):4180-92. Epub 2014 Feb 7.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy; Department of Neurology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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August 2014

Genetic burden of common variants in progressive and bout-onset multiple sclerosis.

Mult Scler 2014 06 25;20(7):802-11. Epub 2013 Nov 25.

Laboratory of Genetics of Neurological Complex Disorders, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Italy Department of Neurology, Institute of Experimental Neurology (INSPE), Division of Neuroscience, San Raffaele Scientific Institute, Italy

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June 2014

Deep grey matter T2 hypo-intensity in patients with paediatric multiple sclerosis.

Mult Scler 2011 Jun 12;17(6):702-7. Epub 2011 Jan 12.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, Scientific Institute and University Ospedale San Raffaele, Via Olgettina 60, Milan, Italy.

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June 2011

MGAT5 and disease severity in progressive multiple sclerosis.

J Neuroimmunol 2011 Jan 27;230(1-2):143-7. Epub 2010 Nov 27.

INSPE and Department of Neurology, Division of Neuroscience, San Raffaele Scientific Institute, 20132 Milan, Italy.

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January 2011

Brain macro- and microscopic damage in patients with paediatric MS.

J Neurol Neurosurg Psychiatry 2010 Dec 26;81(12):1357-62. Epub 2010 Jul 26.

Neuroimaging Research Unit, Institute of Experimental Neurology, Division of Neuroscience, Milan, Italy.

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December 2010

Functional and structural connectivity of the motor network in pediatric and adult-onset relapsing-remitting multiple sclerosis.

Radiology 2010 Feb;254(2):541-50

Neuroimaging Research Unit, Institute of Experimental Neurology, Department of Neurology, University Hospital San Raffaele, Via Olgettina 60, 20132 Milan, Italy.

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February 2010

Is a preserved functional reserve a mechanism limiting clinical impairment in pediatric MS patients?

Hum Brain Mapp 2009 Sep;30(9):2844-51

Neuroimaging Research Unit, Scientific Institute and University Ospedale San Raffaele, Milan, Italy.

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September 2009

Marchiafava-Bignami disease: longitudinal MR imaging and MR spectroscopy study.

AJNR Am J Neuroradiol 2003 Feb;24(2):249-53

Neuroradiology Department, Scientific Institute Ospedale San Raffaele, University Vita-Salute San Raffaele, Via Olgettina 60, 20132 Milan, Italy.

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February 2003