Luca Valenti

Luca Valenti

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Luca Valenti

Luca Valenti

Publications by authors named "Luca Valenti"

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FibroScan Identifies Patients With Nonalcoholic Fatty Liver Disease and Cardiovascular Damage.

Clin Gastroenterol Hepatol 2020 Feb 8;18(2):517-519. Epub 2018 Dec 8.

Sezione di Gastroenterologia e Epatologia, Di.Bi.M.I.S., University of Palermo, Palermo, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2018.11.011DOI Listing
February 2020

Impact of natural neuromedin-B receptor variants on iron metabolism.

Am J Hematol 2020 Feb 16;95(2):167-177. Epub 2019 Dec 16.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.

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http://dx.doi.org/10.1002/ajh.25679DOI Listing
February 2020

Macrophage MerTK Promotes Liver Fibrosis in Nonalcoholic Steatohepatitis.

Cell Metab 2020 Feb 12;31(2):406-421.e7. Epub 2019 Dec 12.

Department of Medicine, Columbia University Irving Medical Center, New York, NY 10032, USA; Departments of Pathology & Cell Biology and Physiology & Cellular Biophysics, Columbia University Irving Medical Center, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.11.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7004886PMC
February 2020

Uncovering the genetics of cirrhosis: New plots for the usual suspects.

Authors:
Luca Valenti

Liver Int 2020 Feb;40(2):281-282

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.

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http://dx.doi.org/10.1111/liv.14333DOI Listing
February 2020

Virtual genetic diagnosis for familial hypercholesterolemia powered by machine learning.

Eur J Prev Cardiol 2020 Feb 4:2047487319898951. Epub 2020 Feb 4.

Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, Wallenberg Laboratory, University of Gothenburg, Sweden.

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http://dx.doi.org/10.1177/2047487319898951DOI Listing
February 2020

Mboat7 down-regulation by hyper-insulinemia induces fat accumulation in hepatocytes.

EBioMedicine 2020 Feb 11;52:102658. Epub 2020 Feb 11.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Ospedale Policlinico via F Sforza 35, 20122 Milano, Italy; Translational Medicine, Department of Transfusion Medicine and Hematology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2020.102658DOI Listing
February 2020

AISF update on the diagnosis and management of adult-onset lysosomal storage diseases with hepatic involvement.

Dig Liver Dis 2020 Jan 2. Epub 2020 Jan 2.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, and Translational Medicine, Department of Transfusion Medicine and Hematology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2019.12.005DOI Listing
January 2020

Leveraging Human Genetics to Identify Potential New Treatments for Fatty Liver Disease.

Cell Metab 2020 Jan;31(1):35-45

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Translational Medicine, Department of Transfusion Medicine and Hematology, Fondazione IRCCS Ca' Granda, Pad Marangoni, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.12.002DOI Listing
January 2020

GENETICS AND EPIGENETICS IN THE CLINIC: PRECISION MEDICINE IN THE MANAGEMENT OF FATTY LIVER DISEASE.

Curr Pharm Des 2020 Jan 22. Epub 2020 Jan 22.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan. Italy.

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http://dx.doi.org/10.2174/1381612826666200122151251DOI Listing
January 2020

Genetics of Nonalcoholic Fatty Liver Disease: A 2018 Update.

Curr Pharm Des 2018 ;24(38):4566-4573

Internal Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Department of Pathophysiology and Transplantation, Universita degli Studi di Milano, Milan, Italy.

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http://dx.doi.org/10.2174/1381612825666190119113836DOI Listing
November 2019

Contribution of a genetic risk score to clinical prediction of hepatic steatosis in obese children and adolescents.

Dig Liver Dis 2019 11 27;51(11):1586-1592. Epub 2019 Jun 27.

Pediatric Diabetes and Metabolic Disorders Unit, Department of Surgery, Dentistry, Pediatrics and Gynaecology, University Hospital of Verona, Verona, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2019.05.029DOI Listing
November 2019

Uncovering occult hepatitis B in blood donations: a tale of two worlds.

Blood Transfus 2019 11 11;17(6):399-400. Epub 2019 Dec 11.

Department of Transfusion Medicine and Haematology, "Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico", Milan, Italy.

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http://dx.doi.org/10.2450/2019.0302-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6917529PMC
November 2019

Prevalence and Risk Factors of Significant Fibrosis in Patients With Nonalcoholic Fatty Liver Without Steatohepatitis.

Clin Gastroenterol Hepatol 2019 Oct 29;17(11):2310-2319.e6. Epub 2019 Jan 29.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; Department of Transfusion Medicine and Hematology, Translational Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2019.01.027DOI Listing
October 2019

Whole exome sequencing for personalized hepatology: Expanding applications in adults and challenges.

J Hepatol 2019 Oct 27;71(4):849-850. Epub 2019 Jul 27.

Translational Medicine, Department of Transfusion Medicine and Hematology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milano, Italy.

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http://dx.doi.org/10.1016/j.jhep.2019.06.008DOI Listing
October 2019

Liver International: Anticipating the future of hepatology worldwide.

Liver Int 2019 Oct;39(10):1796-1797

Liver Unit, Barcelona Clinic Liver Cancer (BCLC) Group, Hospital Clinic Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1111/liv.14240DOI Listing
October 2019

β-Klotho gene variation is associated with liver damage in children with NAFLD.

J Hepatol 2019 Oct 23. Epub 2019 Oct 23.

Research Unit of Molecular Genetics of Complex Phenotypes, Bambino Gesù Children's Hospital - IRCCS, Rome, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2019.10.011DOI Listing
October 2019

mir-101-3p Downregulation Promotes Fibrogenesis by Facilitating Hepatic Stellate Cell Transdifferentiation During Insulin Resistance.

Nutrients 2019 Oct 29;11(11). Epub 2019 Oct 29.

General Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano 20122, Italy.

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http://dx.doi.org/10.3390/nu11112597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6893471PMC
October 2019

NAFLD in children: new genes, new diagnostic modalities and new drugs.

Nat Rev Gastroenterol Hepatol 2019 09 5;16(9):517-530. Epub 2019 Jul 5.

Texas Liver Institute, UT Health San Antonio, San Antonio, TX, USA.

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http://dx.doi.org/10.1038/s41575-019-0169-zDOI Listing
September 2019

Accuracy of imaging methods for steatohepatitis diagnosis in non-alcoholic fatty liver disease patients: A systematic review.

Liver Int 2019 Aug 8;39(8):1521-1534. Epub 2019 May 8.

Epidemiology Unit, Azienda Unità Sanitaria Locale-IRCCS of Reggio Emilia, Reggio Emilia, Italy.

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http://dx.doi.org/10.1111/liv.14118DOI Listing
August 2019

Novel Insights into the Genetic Landscape of Nonalcoholic Fatty Liver Disease.

Int J Environ Res Public Health 2019 08 1;16(15). Epub 2019 Aug 1.

Translational Medicine, Department of Transfusion Medicine and Hematology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico IRCCS, 20122 Milan, Italy.

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http://dx.doi.org/10.3390/ijerph16152755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6695718PMC
August 2019

Association between Helicobacter pylori infection and risk of nonalcoholic fatty liver disease: An updated meta-analysis.

Metabolism 2019 07 29;96:56-65. Epub 2019 Apr 29.

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2019.04.012DOI Listing
July 2019

Preliminary Evidences of Safety and Efficacy of Flavonoids- and Omega 3-Based Compound for Muscular Dystrophies Treatment: A Randomized Double-Blind Placebo Controlled Pilot Clinical Trial.

Front Neurol 2019 23;10:755. Epub 2019 Jul 23.

Stem Cell Laboratory, Unit of Neurology, Department of Pathophysiology and Transplantation, Centro Dino Ferrari, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

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http://dx.doi.org/10.3389/fneur.2019.00755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664031PMC
July 2019

FGF23 and Fetuin-A Interaction in the Liver and in the Circulation.

Int J Biol Sci 2018 25;14(6):586-598. Epub 2018 Apr 25.

Renal Research Laboratory Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

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http://dx.doi.org/10.7150/ijbs.23256DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001652PMC
June 2019

Post-transplant metabolic syndrome in children: Know better to cure better.

Pediatr Transplant 2019 05 21;23(3):e13367. Epub 2019 Feb 21.

Division of Abdominal Transplantation and Hepatobiliopancreatic Surgery, Bambino Gesù Children's Research Hospital IRCCS, Rome, Italy.

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http://dx.doi.org/10.1111/petr.13367DOI Listing
May 2019

Pnpla3 silencing with antisense oligonucleotides ameliorates nonalcoholic steatohepatitis and fibrosis in Pnpla3 I148M knock-in mice.

Mol Metab 2019 04 5;22:49-61. Epub 2019 Feb 5.

Department of Molecular and Clinical Medicine, University of Gothenburg, Sweden; Clinical Nutrition Unit, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy; Cardiology Department, Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.molmet.2019.01.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437635PMC
April 2019

Building mass to prevent non-alcoholic fatty liver disease?

Hepatobiliary Surg Nutr 2019 Apr;8(2):173-176

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan Italy.

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http://dx.doi.org/10.21037/hbsn.2018.12.07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6503256PMC
April 2019

Does nonalcoholic fatty liver disease cause cardiovascular disease? Current knowledge and gaps.

Atherosclerosis 2019 03 30;282:110-120. Epub 2019 Jan 30.

Department of Molecular and Clinical Medicine Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; Clinical Nutrition Unit, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy.

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http://dx.doi.org/10.1016/j.atherosclerosis.2019.01.029DOI Listing
March 2019

Hepatic fat as clinical outcome and therapeutic target for nonalcoholic fatty liver disease.

Liver Int 2019 02 17;39(2):250-256. Epub 2018 Oct 17.

Department of Pathophysiology and Transplantation, University of Milan, and Internal Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milano, Milan, Italy.

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http://dx.doi.org/10.1111/liv.13972DOI Listing
February 2019

Beyond fat accumulation, NAFLD genetics converges on lipid droplet biology.

J Lipid Res 2019 01 12;60(1):7-8. Epub 2018 Nov 12.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy

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http://dx.doi.org/10.1194/jlr.C091116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314259PMC
January 2019

NGM282: a step forward in the nonalcoholic steatohepatitis treatment landscape?

Hepatobiliary Surg Nutr 2018 Dec;7(6):484-486

Hepatology, Gastroenterology and Nutrition Unit, IRCCS "Bambino Gesù" Children's Hospital, Rome, Italy.

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http://dx.doi.org/10.21037/hbsn.2018.10.03DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295393PMC
December 2018

Genetics and epigenetics of NAFLD and NASH: Clinical impact.

J Hepatol 2018 02 6;68(2):268-279. Epub 2017 Nov 6.

Department of Molecular and Clinical Medicine, The Sahlgrenska Academy, University of Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2017.09.003DOI Listing
February 2018

Nonalcoholic Fatty Liver Disease in Children.

Semin Liver Dis 2018 02 22;38(1):1-13. Epub 2018 Feb 22.

Hepatometabolic Disease Unit, Bambino Gesù Children's Hospital, IRCCS (Instituto di Ricovero e Cura a Carattere Scientifico), Rome, Italy.

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http://dx.doi.org/10.1055/s-0038-1627456DOI Listing
February 2018

Subclinical cerebrovascular disease in NAFLD without overt risk factors for atherosclerosis.

Atherosclerosis 2018 01 16;268:27-31. Epub 2017 Nov 16.

Department of Internal Medicine, IRCCS Ca' Granda Ospedale Maggiore Policlinico Foundation, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1016/j.atherosclerosis.2017.11.012DOI Listing
January 2018

Degradation of PHLPP2 by KCTD17, via a Glucagon-Dependent Pathway, Promotes Hepatic Steatosis.

Gastroenterology 2017 12 30;153(6):1568-1580.e10. Epub 2017 Aug 30.

Department of Medicine, Columbia University, New York, NY. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.08.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705280PMC
December 2017

Telomeric zinc-finger associated protein (TZAP): a new player in telomere diseases?

Ann Transl Med 2017 Dec;5(23):472

Department of Pathophysiology and Transplantation, Internal Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Policlinico Hospital, Università degli Studi di Milano, Milano, Italy.

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http://dx.doi.org/10.21037/atm.2017.09.37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733329PMC
December 2017

myVCF: a desktop application for high-throughput mutations data management.

Bioinformatics 2017 Nov;33(22):3676-3678

Internal Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.

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http://dx.doi.org/10.1093/bioinformatics/btx475DOI Listing
November 2017

Identification and characterization of two novel mutations in the LPL gene causing type I hyperlipoproteinemia.

J Clin Lipidol 2016 Jul-Aug;10(4):816-823. Epub 2016 Mar 10.

Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden; Clinical Nutrition Unit, Department of Medical and Surgical Sciences, Magna Graecia University, Catanzaro, Italy; Cardiology Department, Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jacl.2016.02.015DOI Listing
October 2017

Liver and Cardiovascular Damage in Patients With Lean Nonalcoholic Fatty Liver Disease, and Association With Visceral Obesity.

Clin Gastroenterol Hepatol 2017 Oct 26;15(10):1604-1611.e1. Epub 2017 May 26.

Department of Pathophysiology and Transplantation, Unit of Metabolic and Internal Medicine, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1016/j.cgh.2017.04.045DOI Listing
October 2017

Mutant PNPLA3 I148M protein as pharmacological target for liver disease.

Hepatology 2017 10 26;66(4):1026-1028. Epub 2017 Aug 26.

Internal Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Ospedale Policlinico Milano, Milan, Italy.

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http://doi.wiley.com/10.1002/hep.29298
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http://dx.doi.org/10.1002/hep.29298DOI Listing
October 2017

Iron overload induces hypogonadism in male mice via extrahypothalamic mechanisms.

Mol Cell Endocrinol 2017 10 23;454:135-145. Epub 2017 Jun 23.

Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, 20133 Milan, Italy.

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http://dx.doi.org/10.1016/j.mce.2017.06.019DOI Listing
October 2017

Metabolic syndrome and severity of fibrosis in nonalcoholic fatty liver disease: An age-dependent risk profiling study.

Liver Int 2017 09 13;37(9):1389-1396. Epub 2017 Mar 13.

Section of Gastroenterology, Dipartimento Biomedico di Medicina Interna e Specialistica, University of Palermo, Palermo, Italy.

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http://dx.doi.org/10.1111/liv.13397DOI Listing
September 2017

The effect of the TM6SF2 E167K variant on liver steatosis and fibrosis in patients with chronic hepatitis C: a meta-analysis.

Sci Rep 2017 08 24;7(1):9273. Epub 2017 Aug 24.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.

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http://dx.doi.org/10.1038/s41598-017-09548-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571206PMC
August 2017

A Nutrigenomic Approach to Non-Alcoholic Fatty Liver Disease.

Int J Mol Sci 2017 Jul 16;18(7). Epub 2017 Jul 16.

Internal Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Ospedale Policlinico Milano, Milan 20122, Italy.

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http://dx.doi.org/10.3390/ijms18071534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5536022PMC
July 2017

HFE mutations and iron in hemodialysis patients.

Hemodial Int 2017 06 15;21 Suppl 1:S47-S57. Epub 2017 Mar 15.

Department of Pathophysiology and Transplantation, Internal Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, Milano, Italy.

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http://dx.doi.org/10.1111/hdi.12541DOI Listing
June 2017

GNPAT p.D519G variant and iron metabolism during oral iron tolerance test.

Hepatology 2017 01 24;65(1):384-385. Epub 2016 Aug 24.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Internal Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Ospedale, Maggiore Policlinico, Milan, Italy.

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http://dx.doi.org/10.1002/hep.28745DOI Listing
January 2017

Pathophysiology of Non Alcoholic Fatty Liver Disease.

Int J Mol Sci 2016 Dec 11;17(12). Epub 2016 Dec 11.

Department of Clinical and Experimental Medicine, University of Pisa, PC 56122, Pisa, Italy.

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http://www.mdpi.com/1422-0067/17/12/2082
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http://dx.doi.org/10.3390/ijms17122082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5187882PMC
December 2016

The role of insulin resistance in nonalcoholic steatohepatitis and liver disease development--a potential therapeutic target?

Expert Rev Gastroenterol Hepatol 2016 5;10(2):229-42. Epub 2015 Dec 5.

a Department of Pathophysiology and Transplantation , Università degli Studi di Milano, and Internal Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Ospedale Policlinico Milano , Milano , Italy.

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http://dx.doi.org/10.1586/17474124.2016.1110018DOI Listing
November 2016

Nonalcoholic fatty liver disease: cause or consequence of type 2 diabetes?

Liver Int 2016 11 30;36(11):1563-1579. Epub 2016 Jun 30.

Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, University and Azienda Ospedaliera Universitaria Integrata of Verona, Verona, Italy.

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http://dx.doi.org/10.1111/liv.13185DOI Listing
November 2016

Regulation of retinol-binding protein 4 and retinol metabolism in fatty liver disease.

Hepatology 2016 11 13;64(5):1414-1416. Epub 2016 Aug 13.

Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Policlinico Milano, Department of Pathophysiology and Transplantation, Milan, Italy.

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http://dx.doi.org/10.1002/hep.28722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129561PMC
November 2016

Hepcidin resistance in dysmetabolic iron overload.

Liver Int 2016 10 6;36(10):1540-8. Epub 2016 Apr 6.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.

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http://dx.doi.org/10.1111/liv.13124DOI Listing
October 2016

Destined to develop NAFLD? The predictors of fatty liver from birth to adulthood.

J Hepatol 2016 10 16;65(4):668-670. Epub 2016 Jun 16.

Sahlgrenska Center for Cardiovascular and Metabolic Research, Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Department of Cardiology, University of Gothenburg, Sweden; Clinical Nutrition Unit, Department of Medical and Surgical Sciences, University Magna Graecia, Catanzaro, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2016.06.010DOI Listing
October 2016

Genetics of nonalcoholic fatty liver disease.

Metabolism 2016 Aug 1;65(8):1026-37. Epub 2015 Sep 1.

Internal Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico; Department of Pathophysiology and Transplantation, Università degli Studi Milano, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2015.08.018DOI Listing
August 2016

Liver fat accumulation is associated with circulating PCSK9.

Ann Med 2016 08 25;48(5):384-91. Epub 2016 May 25.

d Internal Medicine and Metabolic Diseases , Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico , Milano , Italy ;

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http://dx.doi.org/10.1080/07853890.2016.1188328DOI Listing
August 2016

Genetic Factors in the Pathogenesis of Nonalcoholic Fatty Liver and Steatohepatitis.

Biomed Res Int 2015 27;2015:460190. Epub 2015 Jul 27.

Internal Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, 20122 Milan, Italy ; Department of Pathophysiology and Transplantation, University of Milan, Via Francesco Sforza 35, 20122 Milan, Italy.

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http://downloads.hindawi.com/journals/bmri/2015/460190.pdf
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http://www.hindawi.com/journals/bmri/2015/460190/
Publisher Site
http://dx.doi.org/10.1155/2015/460190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4530215PMC
May 2016

The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent.

Gastroenterology 2016 05 2;150(5):1219-1230.e6. Epub 2016 Feb 2.

Department of Molecular and Clinical Medicine, University of Gothenburg, Sweden; Clinical Nutrition Unit, Department of Medical and Surgical Sciences, University Magna Graecia, Catanzaro, Italy; Cardiology Department, Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2016.01.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844071PMC
May 2016

Reply.

Hepatology 2016 Mar 3;63(3):1052-3. Epub 2015 Jul 3.

Internal Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, and Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.

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http://dx.doi.org/10.1002/hep.27901DOI Listing
March 2016

A "systems medicine" approach to the study of non-alcoholic fatty liver disease.

Dig Liver Dis 2016 Mar 14;48(3):333-42. Epub 2015 Nov 14.

General Medicine 2, Department of Clinical and Experimental Medicine, University Hospital of Pisa, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.dld.2015.10.027DOI Listing
March 2016

Progression of carotid vascular damage and cardiovascular events in non-alcoholic fatty liver disease patients compared to the general population during 10 years of follow-up.

Atherosclerosis 2016 Mar 12;246:208-13. Epub 2016 Jan 12.

Department of Pathophysiology and Transplantation, Ca' Granda Foundation IRCCS Maggiore Policlinico Hospital, University of Milan, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2016.01.016DOI Listing
March 2016

Nutritional therapy for nonalcoholic fatty liver disease.

J Nutr Biochem 2016 Mar 23;29:1-11. Epub 2015 Oct 23.

Internal Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy; Department of Pathophysiology and Transplantation (DEPT), Università degli Studi di Milano, 20122 Milano, Italy.

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http://dx.doi.org/10.1016/j.jnutbio.2015.08.024DOI Listing
March 2016

Telomeres, NAFLD and Chronic Liver Disease.

Int J Mol Sci 2016 Mar 15;17(3):383. Epub 2016 Mar 15.

Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Policlinico Milano, 20122 Milano, Italy.

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http://dx.doi.org/10.3390/ijms17030383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813240PMC
March 2016

High fat diet subverts hepatocellular iron uptake determining dysmetabolic iron overload.

PLoS One 2015 3;10(2):e0116855. Epub 2015 Feb 3.

Internal Medicine and Metabolic Diseases, Fondazione IRCCS Ca' Granda Ospedale Policlinico, Milano, Italy; Department of Pathophysiology and Transplantation, Metabolic Liver Diseases Research Center, Università degli Studi di Milano, Milano, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0116855PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315491PMC
January 2016

PNPLA3 148M Carriers with Inflammatory Bowel Diseases Have Higher Susceptibility to Hepatic Steatosis and Higher Liver Enzymes.

Inflamm Bowel Dis 2016 Jan;22(1):134-40

*Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden; †Division of Gastroenterology, Fondazione Tommaso Campanella, University Magna Graecia of Catanzaro, Catanzaro, Italy; ‡Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Policlinico, and DEPT, Università degli Studi di Milano, Milano, Italy; §Department of Medical and Surgical Sciences, Clinical Nutrition Unit, University Magna Graecia of Catanzaro, Catanzaro, Italy; ‖University Magna Graecia of Catanzaro, Catanzaro, Italy; ¶Unit of Gastroenterology, Fondazione IRCCS Ca' Granda-Ospedale Policlinico Milano, Milan, Italy; **Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy; and ††Cardiology Department, Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1097/MIB.0000000000000569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894778PMC
January 2016

Reply to "Statin treatment for non-alcoholic steatohepatitis".

J Hepatol 2016 Jan 8;64(1):242-3. Epub 2015 Oct 8.

Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Policlinico Milano, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2015.09.023DOI Listing
January 2016

Increased circulating adiponectin in males with chronic HCV hepatitis.

Eur J Intern Med 2015 Oct 17;26(8):635-9. Epub 2015 Aug 17.

Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico Milano, Department of Pathophysiology and Transplantation, Centro Malattie Metaboliche del Fegato, Università degli Studi di Milano, Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.ejim.2015.08.001DOI Listing
October 2015

Statin use and non-alcoholic steatohepatitis in at risk individuals.

J Hepatol 2015 Sep 14;63(3):705-12. Epub 2015 May 14.

Internal Medicine, Fondazione IRCCS Ca' Granda Ospedale Policlinico Milano, Milan, Italy; Department of Pathophysiology and Transplantation (R.R., S.F., L.V.), Università degli Studi di Milano, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jhep.2015.05.006DOI Listing
September 2015

PNPLA3 I148M Variant Influences Circulating Retinol in Adults with Nonalcoholic Fatty Liver Disease or Obesity.

J Nutr 2015 Aug 1;145(8):1687-91. Epub 2015 Jul 1.

Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden; Department of Medical and Surgical Sciences, Clinical Nutrition Unit, University Magna Graecia of Catanzaro, Catanzaro, Italy; and Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden

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http://dx.doi.org/10.3945/jn.115.210633DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516767PMC
August 2015

DNA methylation profiling of the X chromosome reveals an aberrant demethylation on CXCR3 promoter in primary biliary cirrhosis.

Clin Epigenetics 2015 7;7:61. Epub 2015 Jul 7.

Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis School of Medicine, Genome and Biomedical Sciences Facility, 451 Health Sciences Drive, Suite 6510, Davis, CA 95616 USA.

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http://dx.doi.org/10.1186/s13148-015-0098-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491885PMC
July 2015

Paradoxical dissociation between hepatic fat content and de novo lipogenesis due to PNPLA3 sequence variant.

J Clin Endocrinol Metab 2015 May 12;100(5):E821-5. Epub 2015 Mar 12.

Department of Molecular and Clinical Medicine (R.M.M, C.M, S.R., J.B.), University of Gothenburg, S-413 45 Gothenburg, Sweden; Department of Medicine, Cardiovascular Research Unit, Diabetes and Obesity Research Program (N.M., S.S., M.-R.T.), Heart and Lung Centre and Division of Endocrinology and Helsinki University Central Hospital, University of Helsinki, 00100 Helsinki, Finland; Department of Radiology, HUS Medical Imaging Center (N.L., A.H.), Helsinki University Central Hospital, University of Helsinki, 00100 Helsinki, Finland; Departments of Internal Medicine (R.R, S.F., L.V.), and General Surgery (E.M.), Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca' Granda Ospedale Policlinico, and Department of Pathophysiology and Transplantation Università degli Studi di Milano, 20122 Milano, Italy; and Department of Medical and Surgical Sciences (S.R.), Clinical Nutrition Unit, University Magna Graecia of Catanzaro, 88100 Catanzaro, Italy.

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http://dx.doi.org/10.1210/jc.2014-4464DOI Listing
May 2015