Luca Malcovati

Luca Malcovati

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Luca Malcovati

Publications by authors named "Luca Malcovati"

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CHIP, CCUS, and Other Acronyms: Definition, Implications, and Impact on Practice.

Am Soc Clin Oncol Educ Book 2019 Jan 17;39:400-410. Epub 2019 May 17.

3 Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.

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https://ascopubs.org/doi/10.1200/EDBK_239083
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http://dx.doi.org/10.1200/EDBK_239083DOI Listing
January 2019

Cannibalism by erythroleukaemic blasts.

Br J Haematol 2018 10 24;183(1):14. Epub 2018 May 24.

Department of Haematology Oncology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo Foundation, Pavia, Italy.

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http://dx.doi.org/10.1111/bjh.15422DOI Listing
October 2018

Vascular endothelial growth factor overexpression in myelodysplastic syndrome bone marrow cells: biological and clinical implications.

Leuk Lymphoma 2017 07 29;58(7):1711-1720. Epub 2016 Nov 29.

b Department of Hematology Oncology , IRCCS Policlinico San Matteo Foundation, University of Pavia , Pavia , Italy.

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http://dx.doi.org/10.1080/10428194.2016.1262030DOI Listing
July 2017

Introduction.

Authors:
Luca Malcovati

Semin Hematol 2017 07 20;54(3):129-132. Epub 2017 Jul 20.

Department of Molecular Medicine, University of Pavia and; Department of Hematology Oncology, IRCCS Policlinico S. Matteo Foundation, Pavia, Italy. Electronic address:

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http://dx.doi.org/10.1053/j.seminhematol.2017.07.001DOI Listing
July 2017

The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes.

J Clin Invest 2017 Jun 24;127(6):2206-2221. Epub 2017 Apr 24.

Bloodwise Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, and BRC Blood Theme, National Institute for Health Research (NIHR) Oxford Biomedical Centre, Oxford University Hospital, Oxford, United Kingdom.

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http://dx.doi.org/10.1172/JCI91363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451246PMC
June 2017

Recognition of familial myeloid neoplasia in adults.

Semin Hematol 2017 04 18;54(2):60-68. Epub 2017 Apr 18.

Section of Hematology/Oncology, The University of Chicago Comprehensive Cancer Center, and the Center for Clinical Cancer Genetics, The University of Chicago, Chicago, IL, USA. Electronic address:

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http://dx.doi.org/10.1053/j.seminhematol.2016.11.003DOI Listing
April 2017

Diagnosis and treatment of sideroblastic anemias: from defective heme synthesis to abnormal RNA splicing.

Hematology Am Soc Hematol Educ Program 2015 ;2015:19-25

Department of Hematology Oncology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Policlinico San Matteo, Pavia; and Department of Molecular Medicine, University of Pavia Medical School, Pavia, Italy.

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http://dx.doi.org/10.1182/asheducation-2015.1.19DOI Listing
October 2016

The shadowlands of MDS: idiopathic cytopenias of undetermined significance (ICUS) and clonal hematopoiesis of indeterminate potential (CHIP).

Hematology Am Soc Hematol Educ Program 2015 ;2015:299-307

Department of Molecular Medicine, University of Pavia Medical School, and Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

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http://www.asheducationbook.org/cgi/doi/10.1182/asheducation
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http://dx.doi.org/10.1182/asheducation-2015.1.299DOI Listing
October 2016

Recent advances in the understanding of myelodysplastic syndromes with ring sideroblasts.

Br J Haematol 2016 09 8;174(6):847-58. Epub 2016 Jul 8.

Department of Molecular Medicine, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1111/bjh.14215DOI Listing
September 2016

The genomic landscape of myeloid neoplasms with myelodysplasia and its clinical implications.

Curr Opin Oncol 2015 Nov;27(6):551-9

aDepartment of Molecular Medicine, University of Pavia bDepartment of Hematology Oncology, Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy.

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http://dx.doi.org/10.1097/CCO.0000000000000229DOI Listing
November 2015

Somatic mutations of calreticulin in myeloproliferative neoplasms and myelodysplastic/myeloproliferative neoplasms.

Haematologica 2014 Nov;99(11):1650-2

Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo, and Department of Molecular Medicine, University of Pavia, Pavia, Italy

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http://dx.doi.org/10.3324/haematol.2014.113944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222470PMC
November 2014

Driver somatic mutations identify distinct disease entities within myeloid neoplasms with myelodysplasia.

Blood 2014 Aug 26;124(9):1513-21. Epub 2014 Jun 26.

Department of Molecular Medicine, University of Pavia, Pavia, Italy; Department of Hematology Oncology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy;

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http://dx.doi.org/10.1182/blood-2014-03-560227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148773PMC
August 2014

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.

Cancer Cell 2014 Jun 15;25(6):794-808. Epub 2014 May 15.

Haematopoietic Stem Cell Biology Laboratory, MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK; Departments of Cell and Molecular Biology, Medicine Huddinge, and Laboratory Medicine, Huddinge, Karolinska Institutet and Center for Hematology and Regenerative Medicine, Karolinska University Hospital Huddinge, 141 86 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ccr.2014.03.036DOI Listing
June 2014

The genetic basis of myelodysplasia and its clinical relevance.

Blood 2013 Dec 17;122(25):4021-34. Epub 2013 Oct 17.

Department of Hematology Oncology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy; and.

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http://dx.doi.org/10.1182/blood-2013-09-381665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862275PMC
December 2013

Somatic mutations of calreticulin in myeloproliferative neoplasms.

N Engl J Med 2013 Dec 10;369(25):2379-90. Epub 2013 Dec 10.

From CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences (T.K., A.S.H., H.N., J.D.M., N.C.C.T., T.B., D.C., G.I.V., K.B., F.S., C.C., M. Six, A.S., C.B., G.S.-F., R.K.) and the Department of Internal Medicine I, Division of Hematology and Blood Coagulation, Medical University of Vienna (H.G., B.G., M. Schalling, R.K.) - both in Vienna; and the Department of Hematology Oncology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo (E.R., D.P., C.M., I.C.C., E.S., V.F., C.E., L.M., C.P., M.C.), and the Department of Molecular Medicine, University of Pavia (L.M., M.C.) - both in Pavia, Italy.

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http://dx.doi.org/10.1056/NEJMoa1311347DOI Listing
December 2013

Refractory anemia with ring sideroblasts.

Best Pract Res Clin Haematol 2013 Dec 1;26(4):377-85. Epub 2013 Oct 1.

Department of Molecular Medicine, University of Pavia, Pavia, Italy; Division of Hematology, Department of Hematology Oncology, Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy. Electronic address:

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http://www.rjme.ro/RJME/resources/files/530312645650.pdf
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http://ajcp.oxfordjournals.org/content/ajcpath/135/3/398.ful
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http://linkinghub.elsevier.com/retrieve/pii/S152169261300053
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http://dx.doi.org/10.1016/j.beha.2013.09.005DOI Listing
December 2013

Identification of gene expression-based prognostic markers in the hematopoietic stem cells of patients with myelodysplastic syndromes.

J Clin Oncol 2013 Oct 3;31(28):3557-64. Epub 2013 Sep 3.

Andrea Pellagatti, Janet Perry, James S. Wainscoat, and Jacqueline Boultwood, University of Oxford, Oxford; Ken I. Mills, Queen's University Belfast, Belfast; Emma-Jane McDonald and Sally Killick, Royal Bournemouth Hospital, Bournemouth, United Kingdom; Axel Benner, German Cancer Research Center, Heidelberg; Aristoteles Giagounidis, St Johannes Hospital, Duisburg; Lars Bullinger, University Hospital of Ulm, Ulm, Germany; Mario Cazzola, Luca Malcovati, and Matteo G. Della Porta, Fondazione Istituto di Ricovera e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy; Martin Jädersten and Eva Hellström-Lindberg, Karolinska Institutet, Stockholm, Sweden; and Amit Verma, Albert Einstein College of Medicine, New York, NY.

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http://dx.doi.org/10.1200/JCO.2012.45.5626DOI Listing
October 2013

Management recommendations for chronic myelomonocytic leukemia: consensus statements from the SIE, SIES, GITMO groups.

Haematologica 2013 Sep;98(9):1344-52

Hematology - Bone Marrow Transplantation Center, Fondazione IRCCS Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.

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http://dx.doi.org/10.3324/haematol.2013.084020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762089PMC
September 2013

Effects of mitochondrial ferritin overexpression in normal and sideroblastic erythroid progenitors.

Br J Haematol 2013 Jun 10;161(5):726-37. Epub 2013 Apr 10.

Department of Internal Medicine, University of Pavia Medical School and Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

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http://dx.doi.org/10.1111/bjh.12316DOI Listing
June 2013

Biologic and clinical significance of somatic mutations of SF3B1 in myeloid and lymphoid neoplasms.

Blood 2013 Jan 16;121(2):260-9. Epub 2012 Nov 16.

Department of Hematology Oncology, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy.

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http://dx.doi.org/10.1182/blood-2012-09-399725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790951PMC
January 2013

Myelodysplastic/myeloproliferative neoplasms.

Hematology Am Soc Hematol Educ Program 2011 ;2011:264-72

Department of Hematology Oncology, University of Pavia Medical School and Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

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http://dx.doi.org/10.1182/asheducation-2011.1.264DOI Listing
April 2012

Classification and prognostic evaluation of myelodysplastic syndromes.

Semin Oncol 2011 Oct;38(5):627-34

Department of Hematology Oncology, Fondazione IRCCS Policlinico San Matteo and University of Pavia Medical School, Italy.

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http://dx.doi.org/10.1053/j.seminoncol.2011.04.007DOI Listing
October 2011

Aplastic anemia & MDS International Foundation (AA&MDSIF): Bone Marrow Failure Disease Scientific Symposium 2010.

Leuk Res 2011 Mar 30;35(3):291-4. Epub 2010 Oct 30.

Department of Hematology Oncology, University of Pavia, Pavia, Italy.

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http://dx.doi.org/10.1016/j.leukres.2010.10.010DOI Listing
March 2011

Red blood cell transfusion-dependency implies a poor survival in primary myelofibrosis irrespective of IPSS and DIPSS.

Haematologica 2011 Jan 30;96(1):167-70. Epub 2010 Sep 30.

Department of Hematology Oncology, Division of Hematology, University of Pavia Medical School and Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

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http://dx.doi.org/10.3324/haematol.2010.031831DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012782PMC
January 2011

Sequence variations in mitochondrial ferritin: distribution in healthy controls and different types of patients.

Genet Test Mol Biomarkers 2010 Dec 12;14(6):793-6. Epub 2010 Oct 12.

Genomic Unit for the Diagnosis of Human Pathologies, Center for Genomics, Bioinformatics, and Biostatistics, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1089/gtmb.2010.0076DOI Listing
December 2010

Prognostic classification and risk assessment in myelodysplastic syndromes.

Hematol Oncol Clin North Am 2010 Apr;24(2):459-68

Department of Hematology-Oncology, Medical School, University of Pavia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

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http://dx.doi.org/10.1016/j.hoc.2010.02.005DOI Listing
April 2010

Red blood cell transfusion therapy and iron chelation in patients with myelodysplastic syndromes.

Authors:
Luca Malcovati

Clin Lymphoma Myeloma 2009 ;9 Suppl 3:S305-11

Department of Hematology, University of Pavia & Fondazione, IRCCS Policlinico San Matteo, 27100 Pavia, Italy.

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http://dx.doi.org/10.3816/CLM.2009.s.029DOI Listing
January 2010

Molecular and clinical features of refractory anemia with ringed sideroblasts associated with marked thrombocytosis.

Blood 2009 Oct 19;114(17):3538-45. Epub 2009 Aug 19.

Department of Hematology Oncology, University of Pavia & Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico (IRCCS), Policlinico San Matteo, Pavia, Italy.

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http://dx.doi.org/10.1182/blood-2009-05-222331DOI Listing
October 2009

Clinical relevance of anemia and transfusion iron overload in myelodysplastic syndromes.

Hematology Am Soc Hematol Educ Program 2008 :166-75

Department of Hematology Oncology, University of Pavia & Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

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http://dx.doi.org/10.1182/asheducation-2008.1.166DOI Listing
July 2009

Clinical relevance of bone marrow fibrosis and CD34-positive cell clusters in primary myelodysplastic syndromes.

J Clin Oncol 2009 Feb 22;27(5):754-62. Epub 2008 Dec 22.

Department of Hematology, University of Pavia Medical School, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.

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http://dx.doi.org/10.1200/JCO.2008.18.2246DOI Listing
February 2009

Prognostic relevance of anemia in myelodysplastic syndromes.

Am J Hematol 2008 Oct;83(10):761-2

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http://dx.doi.org/10.1002/ajh.21271DOI Listing
October 2008

Myelodysplastic syndromes: diagnosis and staging.

Cancer Control 2008 Oct;15 Suppl:4-13

Department of Hematology, University of Pavia and Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Policlinico San Matteo, Pavia, Italy.

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http://dx.doi.org/10.1177/107327480801504s02DOI Listing
October 2008

Genome-wide analysis of copy number changes and loss of heterozygosity in myelodysplastic syndrome with del(5q) using high-density single nucleotide polymorphism arrays.

Haematologica 2008 Jul 27;93(7):994-1000. Epub 2008 May 27.

LRF Molecular Haematology Unit, Nuffield Department of Clinical, Laboratory Sciences, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK.

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http://www.haematologica.org/cgi/doi/10.3324/haematol.12603
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http://dx.doi.org/10.3324/haematol.12603DOI Listing
July 2008