Publications by authors named "Luca Hegedũs"

21Publications

HDAC inhibition synergizes with ALK inhibitors to overcome resistance in a novel ALK mutated lung adenocarcinoma model.

Lung Cancer 2020 06 18;144:20-29. Epub 2020 Apr 18.

Department of Thoracic Surgery, West German Cancer Center, University Hospital Essen - Ruhrlandklinik, University Duisburg-Essen, Essen, Germany. Electronic address:

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June 2020

Multifaceted plasma membrane Ca(2+) pumps: From structure to intracellular Ca(2+) handling and cancer.

Biochim Biophys Acta 2016 Jun 17;1863(6 Pt B):1351-63. Epub 2015 Dec 17.

2(nd) Department of Pathology, Semmelweis University, Budapest, Hungary; Molecular Oncology Research Group of the Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary. Electronic address:

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June 2016

Plasma membrane Ca²⁺-ATPases can shape the pattern of Ca²⁺ transients induced by store-operated Ca²⁺ entry.

Sci Signal 2015 Feb 17;8(364):ra19. Epub 2015 Feb 17.

Hungarian National Blood Transfusion Service, Budapest H-1113, Hungary. 2nd Department of Pathology, Semmelweis University, Budapest H-1091, Hungary. Institute of Molecular Pharmacology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Budapest H-1117, Hungary.

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February 2015

Histone deacetylase inhibitor- and PMA-induced upregulation of PMCA4b enhances Ca2+ clearance from MCF-7 breast cancer cells.

Cell Calcium 2014 Feb 28;55(2):78-92. Epub 2013 Dec 28.

Institute of Molecular Pharmacology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, Budapest, Hungary; Department of Molecular Cell Biology, Hungarian National Blood Transfusion Service, Budapest, Hungary. Electronic address:

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February 2014

Apart from its known function, the plasma membrane Ca²⁺ATPase can regulate Ca²⁺ signaling by controlling phosphatidylinositol 4,5-bisphosphate levels.

J Cell Sci 2014 Jan 6;127(Pt 1):72-84. Epub 2013 Nov 6.

Institute of Molecular Pharmacology, Research Centre for Natural Sciences, Hungarian Academy of Sciences, H-1025 Budapest, Hungary.

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January 2014

A C-terminal di-leucine motif controls plasma membrane expression of PMCA4b.

Biochim Biophys Acta 2013 Dec 2;1833(12):2561-2572. Epub 2013 Jul 2.

Hungarian National Blood Transfusion Service, Budapest, Hungary. Electronic address:

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December 2013

Modulation of endoplasmic reticulum calcium pump expression during lung cancer cell differentiation.

FEBS J 2013 Nov 11;280(21):5408-18. Epub 2012 Dec 11.

Institut National de la Santé et de la Recherche Médicale, UMR-S 940, Paris, France; Institut Universitaire d'Hématologie, Université Paris Diderot, PRES Sorbonne Paris-Cité, France.

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November 2013

Plasma membrane calcium pump (PMCA) isoform 4 is targeted to the apical membrane by the w-splice insert from PMCA2.

Cell Calcium 2012 Feb 16;51(2):171-8. Epub 2012 Jan 16.

Department of Molecular Cell Biology, National Blood Center, Diószegi u. 64, Budapest, Hungary.

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February 2012

Apical localization of PMCA2w/b is enhanced in terminally polarized MDCK cells.

Biochem Biophys Res Commun 2011 Jul 6;410(2):322-7. Epub 2011 Jun 6.

Department of Molecular Cell Biology, National Blood Center, Budapest, Hungary.

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July 2011

Additional MDA-MB-231 breast cancer cell matrix metalloproteinases promote invasiveness.

J Cell Physiol 2008 Aug;216(2):480-5

Department of Pathology, Saint Louis University School of Medicine, St. Louis, Missouri 63104-1028, USA.

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August 2008

Cleavage of the plasma membrane Ca+ATPase during apoptosis.

Ann N Y Acad Sci 2007 Mar;1099:440-50

Membrane Research Group of the Hungarian Academy of Sciences, Budapest H-1051, Hungary.

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March 2007