Luca Carta

Luca Carta

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Luca Carta

Luca Carta

Publications by authors named "Luca Carta"

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Dimorphic effects of transforming growth factor-β signaling during aortic aneurysm progression in mice suggest a combinatorial therapy for Marfan syndrome.

Arterioscler Thromb Vasc Biol 2015 Apr 22;35(4):911-7. Epub 2015 Jan 22.

From the Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, NY (J.R.C., L.C., J.G., E.C., S.S., F.R.); and Genzyme, a Sanofi Company, Framingham, MA (N.P.C., C.A.N., S.H.C., B.M.W.).

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http://dx.doi.org/10.1161/ATVBAHA.114.305150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376614PMC
April 2015

Establishment of fibrillin-deficient osteoprogenitor cell lines identifies molecular abnormalities associated with extracellular matrix perturbation of osteogenic differentiation.

Cell Tissue Res 2011 Jun 3;344(3):511-7. Epub 2011 May 3.

Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029, USA.

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http://link.springer.com/10.1007/s00441-011-1167-9
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http://dx.doi.org/10.1007/s00441-011-1167-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214762PMC
June 2011

Differential effects of alendronate and losartan therapy on osteopenia and aortic aneurysm in mice with severe Marfan syndrome.

Hum Mol Genet 2010 Dec 24;19(24):4790-8. Epub 2010 Sep 24.

Department of Pharmacology and Systems Therapeutics at the Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1093/hmg/ddq409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989889PMC
December 2010

Discrete contributions of elastic fiber components to arterial development and mechanical compliance.

Arterioscler Thromb Vasc Biol 2009 Dec 22;29(12):2083-9. Epub 2009 Oct 22.

Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY 10029, USA.

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http://dx.doi.org/10.1161/ATVBAHA.109.193227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2797476PMC
December 2009

p38 MAPK is an early determinant of promiscuous Smad2/3 signaling in the aortas of fibrillin-1 (Fbn1)-null mice.

J Biol Chem 2009 Feb 24;284(9):5630-6. Epub 2008 Dec 24.

Department of Pharmacology and Systems Therapeutics and the Cardiovascular Institute, Mount Sinai School of Medicine, New York, New York 10029, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M806962200
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http://dx.doi.org/10.1074/jbc.M806962200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645821PMC
February 2009

Fibrillin-rich microfibrils - structural and instructive determinants of mammalian development and physiology.

Connect Tissue Res 2008 ;49(1):1-6

Child Health Institute of New Jersey, Robert W. Johnson Medical School, New Brunswick, New Jersey, USA.

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http://www.tandfonline.com/doi/full/10.1080/0300820070182070
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http://dx.doi.org/10.1080/03008200701820708DOI Listing
March 2008

Fibrillins 1 and 2 perform partially overlapping functions during aortic development.

J Biol Chem 2006 Mar 28;281(12):8016-23. Epub 2005 Dec 28.

Laboratory of Genetics and Organogenesis, Hospital for Special Surgery, the Weill Medical College of Cornell University, New York, New York 10021, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M511599200
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http://dx.doi.org/10.1074/jbc.M511599200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052983PMC
March 2006

Recent progress towards a molecular understanding of Marfan syndrome.

Am J Med Genet C Semin Med Genet 2005 Nov;139C(1):4-9

Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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http://doi.wiley.com/10.1002/ajmg.c.30068
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http://dx.doi.org/10.1002/ajmg.c.30068DOI Listing
November 2005

Diethylstilbestrol exposure in utero: a paradigm for mechanisms leading to adult disease.

Birth Defects Res A Clin Mol Teratol 2005 Mar;73(3):133-5

Brookdale Department of Molecular, Cell and Developmental Biology, Mount Sinai Medical School, New York, New York 10029, USA.

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http://doi.wiley.com/10.1002/bdra.20121
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http://dx.doi.org/10.1002/bdra.20121DOI Listing
March 2005

Wnt7a is a suppressor of cell death in the female reproductive tract and is required for postnatal and estrogen-mediated growth.

Biol Reprod 2004 Aug 7;71(2):444-54. Epub 2004 Apr 7.

Brookdale Department of Developmental, Cellular and Molecular Biology, Mount Sinai School of Medicine, 1 Gustave Levy Place, New York, NY 10029, USA.

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http://dx.doi.org/10.1095/biolreprod.103.026534DOI Listing
August 2004