Luca Agnelli

Luca Agnelli

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Luca Agnelli

Luca Agnelli

Publications by authors named "Luca Agnelli"

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A compendium of long non-coding RNAs transcriptional fingerprint in multiple myeloma.

Sci Rep 2018 04 26;8(1):6557. Epub 2018 Apr 26.

Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy.

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http://dx.doi.org/10.1038/s41598-018-24701-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5920050PMC
April 2018

Long Non-Coding RNAs in Multiple Myeloma.

Genes (Basel) 2018 Feb 1;9(2). Epub 2018 Feb 1.

Department of Oncology and Hemato-Oncology, University of Milan, and Hematology, Fondazione Ca' Granda IRCCS Policlinico, 20122 Milan, Italy.

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http://dx.doi.org/10.3390/genes9020069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852565PMC
February 2018

Correction: miR-451a is underexpressed and targets AKT/mTOR pathway in papillary thyroid carcinoma.

Oncotarget 2018 02 23;9(15):12534. Epub 2018 Feb 23.

Department of Experimental Oncology and Molecular Medicine, Molecular Mechanisms Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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http://dx.doi.org/10.18632/oncotarget.24557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5844767PMC
February 2018

In Silico Characterization of miRNA and Long Non-Coding RNA Interplay in Multiple Myeloma.

Genes (Basel) 2016 Nov 29;7(12). Epub 2016 Nov 29.

Department of Oncology and Hemato-Oncology, University of Milano, 20122 Milan, Italy.

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http://dx.doi.org/10.3390/genes7120107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192483PMC
November 2016

miR-451a is underexpressed and targets AKT/mTOR pathway in papillary thyroid carcinoma.

Oncotarget 2016 Mar;7(11):12731-47

Department of Experimental Oncology and Molecular Medicine, Molecular Mechanisms Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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http://dx.doi.org/10.18632/oncotarget.7262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914318PMC
March 2016

Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts.

Blood 2016 Jan 13;127(2):221-32. Epub 2015 Oct 13.

Department of Molecular Biotechnology and Health Sciences, Center for Experimental Research and Medical Studies, University of Turin, Turin, Italy; Department of Pathology, New York University Cancer Center, New York University School of Medicine, New York, NY.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-12-61
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http://dx.doi.org/10.1182/blood-2014-12-614503DOI Listing
January 2016

Relevance of telomere/telomerase system impairment in early stage chronic lymphocytic leukemia.

Genes Chromosomes Cancer 2014 Jul 4;53(7):612-21. Epub 2014 Apr 4.

Department of Clinical Sciences and Community Health, Center of Molecular and Genetic Epidemiology, University of Milan, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

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http://doi.wiley.com/10.1002/gcc.22171
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http://dx.doi.org/10.1002/gcc.22171DOI Listing
July 2014

Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers.

Nat Med 2014 Jun 11;20(6):599-606. Epub 2014 May 11.

1] Functional Genomics of Cancer Unit, Division of Molecular Oncology, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) San Raffaele Scientific Institute, Milan, Italy. [2] Università Vita-Salute San Raffaele, Milan, Italy. [3] MAGIC (Microenvironment and Genes in Cancers of the blood) Interdivisional Research Program, IRCCS San Raffaele Scientific Institute, Milan, Italy. [4].

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http://dx.doi.org/10.1038/nm.3562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057660PMC
June 2014

Clinical monoclonal B lymphocytosis versus Rai 0 chronic lymphocytic leukemia: A comparison of cellular, cytogenetic, molecular, and clinical features.

Clin Cancer Res 2013 Nov 13;19(21):5890-900. Epub 2013 Sep 13.

Authors' Affiliations: Department of Onco-Hematology, A.O. of Cosenza, Cosenza; Department of Clinical Sciences and Community Health, University of Milano and Hematology 1 CTMO, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano; SS Molecular Diagnostics, Scientific Direction, and Direzione Scientifica, IRCCS, San Martino IST, Genoa; Department of Experimental and Diagnostic Medicine, University of Ferrara, Ferrara; Division of Hematology, A.O. Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia; Division of Hematology, University of Messina, Messina; Department of Oncology and Hematology, Pugliese-Ciaccio Hospital; University of Magna Graecia and Cancer Center, Catanzaro; Division of Hematology, Department of Biomedical Sciences, University of Catania and Ferrarotto Hospital, Catania; and Division of Hematology, Department of Clinical and Experimental Medicine, Amedeo Avogadro University of Eastern Piedmont, Novara, Italy.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-0622DOI Listing
November 2013

Improved risk stratification in myeloma using a microRNA-based classifier.

Br J Haematol 2013 Aug 30;162(3):348-59. Epub 2013 May 30.

Section of Haemato-Oncology, Institute of Cancer Research, Sutton, Surrey, UK.

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http://dx.doi.org/10.1111/bjh.12394DOI Listing
August 2013

Molecular profiling of multiple myeloma: from gene expression analysis to next-generation sequencing.

Expert Opin Biol Ther 2013 Jun 24;13 Suppl 1:S55-68. Epub 2013 Apr 24.

University of Milan, Department of Clinical Sciences and Community Health, F. Sforza, 35 - 20122 Milan, Italy.

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http://dx.doi.org/10.1517/14712598.2013.793305DOI Listing
June 2013

MicroRNAs in the pathobiology of multiple myeloma.

Curr Cancer Drug Targets 2012 Sep;12(7):823-37

Department of Clinical Sciences and Community Health, University of Milan, Hematology 1-CTMO, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.

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http://dx.doi.org/10.2174/156800912802429274DOI Listing
September 2012

Identification of a 3-gene model as a powerful diagnostic tool for the recognition of ALK-negative anaplastic large-cell lymphoma.

Blood 2012 Aug 27;120(6):1274-81. Epub 2012 Jun 27.

Department of Clinical Sciences and Community Health, University of Milano, Hematology 1, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy.

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http://dx.doi.org/10.1182/blood-2012-01-405555DOI Listing
August 2012

The reconstruction of transcriptional networks reveals critical genes with implications for clinical outcome of multiple myeloma.

Clin Cancer Res 2011 Dec 2;17(23):7402-12. Epub 2011 Sep 2.

Department of Medical Sciences, University of Milan and Hematology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Italy.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-0596DOI Listing
December 2011

Overexpression of HOXB7 and homeobox genes characterizes multiple myeloma patients lacking the major primary immunoglobulin heavy chain locus translocations.

Am J Hematol 2011 Dec 22;86(12):E64-6. Epub 2011 Sep 22.

Department of Medical Sciences, University of Milano and Hematology 1, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

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http://dx.doi.org/10.1002/ajh.22164DOI Listing
December 2011

A SNP microarray and FISH-based procedure to detect allelic imbalances in multiple myeloma: an integrated genomics approach reveals a wide gene dosage effect.

Genes Chromosomes Cancer 2009 Jul;48(7):603-14

Department of Medical Sciences, University of Milano and Hematology 1-CTMO, Fondazione IRCCS Ospedale Maggiore Policlinico Mangiagalli Regina Elena, Milano, Italy.

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http://dx.doi.org/10.1002/gcc.20668DOI Listing
July 2009

Integrative high-resolution microarray analysis of human myeloma cell lines reveals deregulated miRNA expression associated with allelic imbalances and gene expression profiles.

Genes Chromosomes Cancer 2009 Jun;48(6):521-31

Department of Medical Sciences, Leukemia Study Centre, University of Milan, Hematology 1-CTMO, Foundation IRCCS Policlinico, Milan, Italy.

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http://dx.doi.org/10.1002/gcc.20660DOI Listing
June 2009

Identification of primary MAFB target genes in multiple myeloma.

Exp Hematol 2009 Jan 13;37(1):78-86. Epub 2008 Nov 13.

University Medical Center Utrecht, Department of Immunology, Utrecht, The Netherlands; Hubrecht Laboratory, Center for Biomedical Genetics, Utrecht, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S0301472X080041
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http://dx.doi.org/10.1016/j.exphem.2008.08.006DOI Listing
January 2009

Molecular and transcriptional characterization of 17p loss in B-cell chronic lymphocytic leukemia.

Genes Chromosomes Cancer 2008 Sep;47(9):781-93

Centro per lo Studio delle Leucemie, Dipartimento di Scienze Mediche, Università di Milano, U.O. Ematologia 1, Fondazione IRCCS Policlinico, Milano, Italy.

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http://dx.doi.org/10.1002/gcc.20579DOI Listing
September 2008

Molecular and transcriptional characterization of the novel 17p11.2-p12 amplicon in multiple myeloma.

Genes Chromosomes Cancer 2007 Dec;46(12):1109-18

Centro di Genetica Molecolare ed Espressione Genica, Fondazione IRCCS Policlinico, Milan, Italy.

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http://dx.doi.org/10.1002/gcc.20494DOI Listing
December 2007

Relevance of Ras gene mutations in the context of the molecular heterogeneity of multiple myeloma.

Hematol Oncol 2007 Mar;25(1):6-10

Centro di Genetica Molecolare ed Espressione Genica, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milano, Italy.

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http://dx.doi.org/10.1002/hon.801DOI Listing
March 2007

Upregulation of translational machinery and distinct genetic subgroups characterise hyperdiploidy in multiple myeloma.

Br J Haematol 2007 Feb;136(4):565-73

Centro di Genetica Molecolare ed Espressione Genica, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy.

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http://dx.doi.org/10.1111/j.1365-2141.2006.06467.xDOI Listing
February 2007

Integrative genomic analysis reveals distinct transcriptional and genetic features associated with chromosome 13 deletion in multiple myeloma.

Haematologica 2007 Jan;92(1):56-65

Centro di Genetica Molecolare ed Espressione Genica, Padiglione G. Marcora, Fondazione IRCCS Ospedale Policlinico, via Francesco Sforza 35, 20122 Milan, Italy.

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http://dx.doi.org/10.3324/haematol.10414DOI Listing
January 2007

Molecular classification of multiple myeloma: a distinct transcriptional profile characterizes patients expressing CCND1 and negative for 14q32 translocations.

J Clin Oncol 2005 Oct 29;23(29):7296-306. Epub 2005 Aug 29.

UO Ematologia 2, Centro G. Marcora, Ospedale Maggiore Policlinico IRCCS, Dipartimento Scienze Mediche, Università degli Studi di Milano, Via Francesco Sforza 35, 20122 Milano, Italy.

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http://dx.doi.org/10.1200/JCO.2005.01.3870DOI Listing
October 2005

Transcription repression activity is associated with the type I isoform of the MMSET gene involved in t(4;14) in multiple myeloma.

Br J Haematol 2005 Oct;131(2):214-8

U.O. Ematologia 2, Centro Trapianti di Midollo, Dipartimento di Scienze Mediche, Università degli Studi di Milano, Ospedale Maggiore IRCCS Milano, Milan, Italy.

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http://dx.doi.org/10.1111/j.1365-2141.2005.05741.xDOI Listing
October 2005

Gene expression profiling of plasma cell dyscrasias reveals molecular patterns associated with distinct IGH translocations in multiple myeloma.

Oncogene 2005 Apr;24(15):2461-73

Laboratorio di Ematologia Sperimentale e Genetica Molecolare and U.O. Ematologia 1, Dipartimento di Scienze Mediche, Università degli Studi di Milano, Ospedale Maggiore IRCCS, Milano, Italy.

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http://www.nature.com/articles/1208447
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http://dx.doi.org/10.1038/sj.onc.1208447DOI Listing
April 2005

Characterization of oncogene dysregulation in multiple myeloma by combined FISH and DNA microarray analyses.

Genes Chromosomes Cancer 2005 Feb;42(2):117-27

Laboratorio di Ematologia Sperimentale e Genetica Molecolare, UO Ematologia 1, Dipartimento di Scienze Mediche, Università degli Studi di Milano, Ospedale Maggiore IRCCS, Milan, Italy.

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http://dx.doi.org/10.1002/gcc.20123DOI Listing
February 2005