Dr. Lubbert Dijkhuizen, PhD - Groningen Biomolecular Sciences and Biotechnology Institute (GBB) - Professor of Microbiology

Dr. Lubbert Dijkhuizen

PhD

Groningen Biomolecular Sciences and Biotechnology Institute (GBB)

Professor of Microbiology

Groningen, Groningen | Netherlands

ORCID logohttps://orcid.org/0000-0003-2312-7162

Dr. Lubbert Dijkhuizen, PhD - Groningen Biomolecular Sciences and Biotechnology Institute (GBB) - Professor of Microbiology

Dr. Lubbert Dijkhuizen

PhD

Introduction

Primary Affiliation: Groningen Biomolecular Sciences and Biotechnology Institute (GBB) - Groningen, Groningen , Netherlands

Experience

Sep 1990
University of Groningen
Professor of Microbiology
Microbiology

Publications

111Publications

1463Reads

303Profile Views

898PubMed Central Citations

Stimulatory effects of novel glucosylated lactose derivatives GL34 on growth of selected gut bacteria.

Appl Microbiol Biotechnol 2019 Jan 7;103(2):707-718. Epub 2018 Nov 7.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747 AG, Groningen, The Netherlands.

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http://link.springer.com/10.1007/s00253-018-9473-8
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http://dx.doi.org/10.1007/s00253-018-9473-8DOI Listing
January 2019
11 Reads
3.340 Impact Factor

Structural and functional characterization of a family GH53 β-1,4-galactanase from Bacteroides thetaiotaomicron that facilitates degradation of prebiotic galactooligosaccharides.

J Struct Biol 2019 Jan 13;205(1):1-10. Epub 2018 Dec 13.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747AG Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jsb.2018.12.002DOI Listing
January 2019
3 Reads
3.231 Impact Factor

Trans-α-glucosylation of stevioside by the mutant glucansucrase enzyme Gtf180-ΔN-Q1140E improves its taste profile.

Food Chem 2019 Jan 10;272:653-662. Epub 2018 Aug 10.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03088146183142
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http://dx.doi.org/10.1016/j.foodchem.2018.08.025DOI Listing
January 2019
16 Reads
3.391 Impact Factor

Synthesis of novel α-glucans with potential health benefits through controlled glucose release in the human gastrointestinal tract.

Crit Rev Food Sci Nutr 2018 Dec 11:1-24. Epub 2018 Dec 11.

a Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB) , University of Groningen , Groningen , The Netherlands.

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https://www.tandfonline.com/doi/full/10.1080/10408398.2018.1
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http://dx.doi.org/10.1080/10408398.2018.1516621DOI Listing
December 2018
4 Reads
5.176 Impact Factor

Structural characterization of glucosylated GOS derivatives synthesized by the Lactobacillus reuteri GtfA and Gtf180 glucansucrase enzymes.

Carbohydr Res 2018 Dec 22;470:57-63. Epub 2018 Oct 22.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747 AG, Groningen, the Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S00086215183053
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http://dx.doi.org/10.1016/j.carres.2018.10.003DOI Listing
December 2018
12 Reads
1.930 Impact Factor

Mutational Analysis of the Role of the Glucansucrase Gtf180-ΔN Active Site Residues in Product and Linkage Specificity with Lactose as Acceptor Substrate.

J Agric Food Chem 2018 Nov 15;66(47):12544-12554. Epub 2018 Nov 15.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB) , University of Groningen , Nijenborgh 7 , 9747 AG Groningen , The Netherlands.

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http://pubs.acs.org/doi/10.1021/acs.jafc.8b04486
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http://dx.doi.org/10.1021/acs.jafc.8b04486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328278PMC
November 2018
10 Reads
2.912 Impact Factor

Cross-Feeding among Probiotic Bacterial Strains on Prebiotic Inulin Involves the Extracellular -Inulinase of Lactobacillus paracasei Strain W20.

Appl Environ Microbiol 2018 Nov 17;84(21). Epub 2018 Oct 17.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, The Netherlands

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http://dx.doi.org/10.1128/AEM.01539-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193377PMC
November 2018
225 Reads
3.670 Impact Factor

Regional variations in human milk oligosaccharides in Vietnam suggest FucTx activity besides FucT2 and FucT3.

Sci Rep 2018 Nov 14;8(1):16790. Epub 2018 Nov 14.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747 AG, Groningen, The Netherlands.

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http://dx.doi.org/10.1038/s41598-018-34882-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6235895PMC
November 2018
3 Reads
5.080 Impact Factor

Biochemical characterization of a GH70 protein from Lactobacillus kunkeei DSM 12361 with two catalytic domains involving branching sucrase activity.

Appl Microbiol Biotechnol 2018 Sep 24;102(18):7935-7950. Epub 2018 Jul 24.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747 AG, Groningen, The Netherlands.

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http://dx.doi.org/10.1007/s00253-018-9236-6DOI Listing
September 2018
12 Reads
3.340 Impact Factor

Biochemical characterization of two GH70 family 4,6-α-glucanotransferases with distinct product specificity from Lactobacillus aviarius subsp. aviarius DSM 20655.

Food Chem 2018 Jul 31;253:236-246. Epub 2018 Jan 31.

Microbial Physiology,Groningen Biomolecular Sciences and Biotechnology Institute (GBB),University of Groningen,Nijenborgh 7,9747 AG Groningen,The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.foodchem.2018.01.154DOI Listing
July 2018
4 Reads
3.391 Impact Factor

Synthesis of galacto-oligosaccharides derived from lactulose by wild-type and mutant β-galactosidase enzymes from Bacillus circulans ATCC 31382.

Carbohydr Res 2018 Jun 19;465:58-65. Epub 2018 Jun 19.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747 AG, Groningen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.carres.2018.06.009DOI Listing
June 2018
6 Reads
1.930 Impact Factor

Stevia Glycosides: Chemical and Enzymatic Modifications of Their Carbohydrate Moieties to Improve the Sweet-Tasting Quality.

Adv Carbohydr Chem Biochem 2016 29;73:1-72. Epub 2016 Aug 29.

Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/bs.accb.2016.05.001DOI Listing
April 2017
15 Reads
2 Citations
2.100 Impact Factor

Crystal Structure of 4,6-α-Glucanotransferase Supports Diet-Driven Evolution of GH70 Enzymes from α-Amylases in Oral Bacteria.

Structure 2017 02 5;25(2):231-242. Epub 2017 Jan 5.

Laboratory of Biophysical Chemistry, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747 AG Groningen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.str.2016.11.023DOI Listing
February 2017
11 Reads
2 Citations
5.620 Impact Factor

Characterization of the glucansucrase GTF180 W1065 mutant enzymes producing polysaccharides and oligosaccharides with altered linkage composition.

Food Chem 2017 Feb 24;217:81-90. Epub 2016 Aug 24.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.foodchem.2016.08.087DOI Listing
February 2017
15 Reads
1 Citation
3.391 Impact Factor

4,3-α-Glucanotransferase, a novel reaction specificity in glycoside hydrolase family 70 and clan GH-H.

Sci Rep 2017 01 6;7:39761. Epub 2017 Jan 6.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1038/srep39761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216370PMC
January 2017
12 Reads
3 Citations
5.080 Impact Factor

Characterization of the starch-acting MaAmyB enzyme from Microbacterium aurum B8.A representing the novel subfamily GH13_42 with an unusual, multi-domain organization.

Sci Rep 2016 11 3;6:36100. Epub 2016 Nov 3.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, The Netherlands.

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http://dx.doi.org/10.1038/srep36100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093618PMC
November 2016
6 Reads
3 Citations
5.080 Impact Factor

Structural basis for the roles of starch and sucrose in homo-exopolysaccharide formation by Lactobacillus reuteri 35-5.

Carbohydr Polym 2016 Oct 17;151:29-39. Epub 2016 May 17.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.carbpol.2016.05.048DOI Listing
October 2016
7 Reads
4.074 Impact Factor

Glucansucrase Gtf180-ΔN of Lactobacillus reuteri 180: enzyme and reaction engineering for improved glycosylation of non-carbohydrate molecules.

Appl Microbiol Biotechnol 2016 Sep 6;100(17):7529-39. Epub 2016 Apr 6.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747 AG, Groningen, The Netherlands.

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http://dx.doi.org/10.1007/s00253-016-7476-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980424PMC
September 2016
18 Reads
1 Citation
3.340 Impact Factor

Structure-function relationships of family GH70 glucansucrase and 4,6-α-glucanotransferase enzymes, and their evolutionary relationships with family GH13 enzymes.

Cell Mol Life Sci 2016 07 7;73(14):2681-706. Epub 2016 May 7.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747, AG, Groningen, The Netherlands.

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http://dx.doi.org/10.1007/s00018-016-2245-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919382PMC
July 2016
16 Reads
6 Citations
5.810 Impact Factor

The Gram-negative bacterium Azotobacter chroococcum NCIMB 8003 employs a new glycoside hydrolase family 70 4,6-α-glucanotransferase enzyme (GtfD) to synthesize a reuteran like polymer from maltodextrins and starch.

Biochim Biophys Acta 2016 Jun 8;1860(6):1224-36. Epub 2016 Feb 8.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2016.02.005DOI Listing
June 2016
9 Reads
4 Citations

Carbohydrate-binding module 74 is a novel starch-binding domain associated with large and multidomain α-amylase enzymes.

FEBS J 2016 06 11;283(12):2354-68. Epub 2016 May 11.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), The Netherlands.

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http://dx.doi.org/10.1111/febs.13745DOI Listing
June 2016
15 Reads
3 Citations
4.001 Impact Factor

Glucosylation of Catechol with the GTFA Glucansucrase Enzyme from Lactobacillus reuteri and Sucrose as Donor Substrate.

Bioconjug Chem 2016 Apr 8;27(4):937-46. Epub 2016 Mar 8.

Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen , Nijenborgh 7, 9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1021/acs.bioconjchem.6b00018DOI Listing
April 2016
8 Reads
2 Citations
4.513 Impact Factor

Lactobacillus reuteri Strains Convert Starch and Maltodextrins into Homoexopolysaccharides Using an Extracellular and Cell-Associated 4,6-α-Glucanotransferase.

J Agric Food Chem 2016 Apr 30;64(14):2941-52. Epub 2016 Mar 30.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen , Nijenborgh 7, 9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1021/acs.jafc.6b00714DOI Listing
April 2016
8 Reads
1 Citation
2.912 Impact Factor

The Exiguobacterium sibiricum 255-15 GtfC Enzyme Represents a Novel Glycoside Hydrolase 70 Subfamily of 4,6-α-Glucanotransferase Enzymes.

Appl Environ Microbiol 2016 01 20;82(2):756-66. Epub 2015 Nov 20.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, The Netherlands

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http://dx.doi.org/10.1128/AEM.03420-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711130PMC
January 2016
17 Reads
6 Citations
3.670 Impact Factor

Synthesis of New Hyperbranched α-Glucans from Sucrose by Lactobacillus reuteri 180 Glucansucrase Mutants.

J Agric Food Chem 2016 Jan 8;64(2):433-42. Epub 2016 Jan 8.

Microbial Physiology and ‡Biophysical Chemistry, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen , Nijenborgh 7, 9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1021/acs.jafc.5b05161DOI Listing
January 2016
9 Reads
5 Citations
2.912 Impact Factor

Structural and Functional Characterization of a Novel Family GH115 4-O-Methyl-α-Glucuronidase with Specificity for Decorated Arabinogalactans.

J Mol Biol 2015 Dec 14;427(24):3935-46. Epub 2015 Jul 14.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, 9747AG Groningen, The Netherlands; York Structural Biology Laboratory, Department of Chemistry, University of York, YO10 5DD, York, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2015.07.006DOI Listing
December 2015
9 Reads
1 Citation
4.333 Impact Factor

Systems approaches to predict the functions of glycoside hydrolases during the life cycle of Aspergillus niger using developmental mutants ∆brlA and ∆flbA.

PLoS One 2015 28;10(1):e0116269. Epub 2015 Jan 28.

Molecular Microbiology and Biotechnology, Institute of Biology Leiden, Kluyver Centre for Genomics of Industrial Fermentation, Leiden University, Leiden, the Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0116269PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309609PMC
October 2015
38 Reads
3 Citations
3.234 Impact Factor

Degradation of Granular Starch by the Bacterium Microbacterium aurum Strain B8.A Involves a Modular α-Amylase Enzyme System with FNIII and CBM25 Domains.

Appl Environ Microbiol 2015 Oct 17;81(19):6610-20. Epub 2015 Jul 17.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, The Netherlands

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http://dx.doi.org/10.1128/AEM.01029-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4561702PMC
October 2015
18 Reads
3 Citations
3.670 Impact Factor

Biochemical Characterization of the Lactobacillus reuteri Glycoside Hydrolase Family 70 GTFB Type of 4,6-α-Glucanotransferase Enzymes That Synthesize Soluble Dietary Starch Fibers.

Appl Environ Microbiol 2015 Oct 7;81(20):7223-32. Epub 2015 Aug 7.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, The Netherlands

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http://dx.doi.org/10.1128/AEM.01860-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579422PMC
October 2015
14 Reads
7 Citations
3.670 Impact Factor

Synthesis of oligo- and polysaccharides by Lactobacillus reuteri 121 reuteransucrase at high concentrations of sucrose.

Carbohydr Res 2015 Sep 23;414:85-92. Epub 2015 Jul 23.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, NL-9747 AG Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.carres.2015.07.011DOI Listing
September 2015
6 Reads
1 Citation
1.930 Impact Factor

A GH57 4-α-glucanotransferase of hyperthermophilic origin with potential for alkyl glycoside production.

Appl Microbiol Biotechnol 2015 Sep 19;99(17):7101-13. Epub 2015 Feb 19.

Biotechnology, Department of Chemistry, Lund University, Getingevägen 60, Lund, 22241, Sweden.

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http://link.springer.com/content/pdf/10.1007/s00253-015-6435
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http://link.springer.com/10.1007/s00253-015-6435-2
Publisher Site
http://dx.doi.org/10.1007/s00253-015-6435-2DOI Listing
September 2015
16 Reads
1 Citation
3.340 Impact Factor

Enzymatic Decoration of Prebiotic Galacto-oligosaccharides (Vivinal GOS) with Sialic Acid Using Trypanosoma cruzi trans-Sialidase and Two Bovine Sialoglycoconjugates as Donor Substrates.

J Agric Food Chem 2015 Jul 22;63(25):5976-84. Epub 2015 Jun 22.

†Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, NL-9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1021/acs.jafc.5b01505DOI Listing
July 2015
9 Reads
2.912 Impact Factor

Truncation of domain V of the multidomain glucansucrase GTF180 of Lactobacillus reuteri 180 heavily impairs its polysaccharide-synthesizing ability.

Appl Microbiol Biotechnol 2015 Jul 15;99(14):5885-94. Epub 2015 Jan 15.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747, AG, Groningen, The Netherlands.

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http://dx.doi.org/10.1007/s00253-014-6361-8DOI Listing
July 2015
8 Reads
5 Citations
3.340 Impact Factor

Biosynthesis of a steroid metabolite by an engineered Rhodococcus erythropolis strain expressing a mutant cytochrome P450 BM3 enzyme.

Appl Microbiol Biotechnol 2015 Jun 16;99(11):4713-21. Epub 2014 Dec 16.

AIMMS-Division of Molecular Toxicology, Department of Chemistry and Pharmaceutical Sciences, Vrije Universiteit, De Boelelaan 1083, 1081 HV, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00253-014-6281-7DOI Listing
June 2015
13 Reads
2 Citations
3.340 Impact Factor

Characterization of the 4,6-α-glucanotransferase GTFB enzyme of Lactobacillus reuteri 121 isolated from inclusion bodies.

BMC Biotechnol 2015 Jun 9;15:49. Epub 2015 Jun 9.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747 AG, Groningen, The Netherlands.

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http://dx.doi.org/10.1186/s12896-015-0163-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459449PMC
June 2015
27 Reads
2 Citations
2.034 Impact Factor

Differential Metabolism of Exopolysaccharides from Probiotic Lactobacilli by the Human Gut Symbiont Bacteroides thetaiotaomicron.

Appl Environ Microbiol 2015 Jun 3;81(12):3973-83. Epub 2015 Apr 3.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1128/AEM.00149-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524142PMC
June 2015
13 Reads
11 Citations
3.670 Impact Factor

Kinetic characterization of Aspergillus niger chitinase CfcI using a HPAEC-PAD method for native chitin oligosaccharides.

Carbohydr Res 2015 Apr 3;407:73-8. Epub 2015 Feb 3.

Microbial Physiology Research Group, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands; Aquatic Biotechnology and Bioproduct Engineering Department, Institute for Technology and Management (ITM), University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.carres.2015.01.014DOI Listing
April 2015
7 Reads
1 Citation
1.930 Impact Factor

Characterization of the starvation-induced chitinase CfcA and α-1,3-glucanase AgnB of Aspergillus niger.

Appl Microbiol Biotechnol 2015 Mar 16;99(5):2209-23. Epub 2014 Sep 16.

Microbial Physiology Research Group, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, The Netherlands,

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http://dx.doi.org/10.1007/s00253-014-6062-3DOI Listing
March 2015
8 Reads
4 Citations
3.340 Impact Factor

(1)H NMR analysis of the lactose/β-galactosidase-derived galacto-oligosaccharide components of Vivinal® GOS up to DP5.

Carbohydr Res 2014 Dec 1;400:59-73. Epub 2014 Sep 1.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, NL-9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.carres.2014.08.012DOI Listing
December 2014
13 Reads
4 Citations
1.930 Impact Factor

Isomalto/malto-polysaccharide, a novel soluble dietary fiber made via enzymatic conversion of starch.

J Agric Food Chem 2014 Dec 1;62(49):12034-44. Epub 2014 Dec 1.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen , 9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1021/jf503970aDOI Listing
December 2014
10 Reads
10 Citations
2.912 Impact Factor

Development of a (1)H NMR structural-reporter-group concept for the analysis of prebiotic galacto-oligosaccharides of the [β-d-Galp-(1→x)]n-d-Glcp type.

Carbohydr Res 2014 Dec 1;400:54-58. Epub 2014 Sep 1.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, NL-9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.carres.2014.08.011DOI Listing
December 2014
8 Reads
2 Citations
1.930 Impact Factor

Galactosyl-lactose sialylation using Trypanosoma cruzi trans-sialidase as the biocatalyst and bovine κ-casein-derived glycomacropeptide as the donor substrate.

Appl Environ Microbiol 2014 Oct 25;80(19):5984-91. Epub 2014 Jul 25.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1128/AEM.01465-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4178701PMC
October 2014
7 Reads
2 Citations
3.670 Impact Factor

Rapid milk group classification by 1H NMR analysis of Le and H epitopes in human milk oligosaccharide donor samples.

Glycobiology 2014 Aug 29;24(8):728-39. Epub 2014 Apr 29.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, NL-9747 AG, Groningen, The Netherlands NMR Spectroscopy, Bijvoet Center for Biomolecular Research, Utrecht University, Padualaan 8, Utrecht 3584 CH, The Netherlands.

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http://dx.doi.org/10.1093/glycob/cwu036DOI Listing
August 2014
7 Reads
6 Citations
3.150 Impact Factor

3-Ketosteroid 9α-hydroxylase enzymes: Rieske non-heme monooxygenases essential for bacterial steroid degradation.

Antonie Van Leeuwenhoek 2014 Jul 21;106(1):157-72. Epub 2014 May 21.

Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747 AG, Groningen, The Netherlands,

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http://dx.doi.org/10.1007/s10482-014-0188-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064121PMC
July 2014
10 Reads
8 Citations
1.810 Impact Factor

Flexibility of truncated and full-length glucansucrase GTF180 enzymes from Lactobacillus reuteri 180.

FEBS J 2014 May 17;281(9):2159-71. Epub 2014 Mar 17.

Laboratory of Biophysical Chemistry, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, The Netherlands.

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http://dx.doi.org/10.1111/febs.12769DOI Listing
May 2014
7 Reads
3 Citations
4.001 Impact Factor

Habitat-specific type I polyketide synthases in soils and street sediments.

J Ind Microbiol Biotechnol 2014 Jan 16;41(1):75-85. Epub 2013 Nov 16.

Department of Biology, University of Ottawa, Ottawa, ON, K1N 6N5, Canada,

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http://dx.doi.org/10.1007/s10295-013-1362-7DOI Listing
January 2014
7 Reads
2 Citations
2.440 Impact Factor

An unconventional glycosyl transfer reaction: glucansucrase GTFA functions as an allosyltransferase enzyme.

Chembiochem 2013 Dec 13;14(18):2423-6. Epub 2013 Nov 13.

Institut für Organische Chemie, Julius-Maximilians-Universität Würzburg, Am Hubland, 97074 Würzburg (Germany).

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http://dx.doi.org/10.1002/cbic.201300392DOI Listing
December 2013
25 Reads
1 Citation
3.090 Impact Factor

Chaplins of Streptomyces coelicolor self-assemble into two distinct functional amyloids.

J Struct Biol 2013 Nov 5;184(2):301-9. Epub 2013 Sep 5.

Electron Microscopy, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jsb.2013.08.013DOI Listing
November 2013
7 Reads
4 Citations
3.231 Impact Factor

Gluco-oligomers initially formed by the reuteransucrase enzyme of Lactobacillus reuteri 121 incubated with sucrose and malto-oligosaccharides.

Glycobiology 2013 Sep 25;23(9):1084-96. Epub 2013 Jun 25.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1093/glycob/cwt048DOI Listing
September 2013
8 Reads
6 Citations
3.150 Impact Factor

Structural investigation of water-soluble polysaccharides extracted from the fruit bodies of Coprinus comatus.

Carbohydr Polym 2013 Jan 20;91(1):314-21. Epub 2012 Aug 20.

School of Food Science, Henan Institute of Science and Technology, Hualan Road, Xinxiang 453003, PR China.

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http://dx.doi.org/10.1016/j.carbpol.2012.08.045DOI Listing
January 2013
6 Reads
4.074 Impact Factor

4,6-α-Glucanotransferase activity occurs more widespread in Lactobacillus strains and constitutes a separate GH70 subfamily.

Appl Microbiol Biotechnol 2013 Jan 25;97(1):181-93. Epub 2012 Feb 25.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747 AG, Groningen, The Netherlands.

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http://dx.doi.org/10.1007/s00253-012-3943-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536977PMC
January 2013
15 Reads
11 Citations
3.340 Impact Factor

Glucansucrases: three-dimensional structures, reactions, mechanism, α-glucan analysis and their implications in biotechnology and food applications.

J Biotechnol 2013 Jan 10;163(2):250-72. Epub 2012 Jul 10.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute-GBB, University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jbiotec.2012.06.037DOI Listing
January 2013
46 Reads
31 Citations
2.871 Impact Factor

Structure of the α-1,6/α-1,4-specific glucansucrase GTFA from Lactobacillus reuteri 121.

Acta Crystallogr Sect F Struct Biol Cryst Commun 2012 Dec 14;68(Pt 12):1448-54. Epub 2012 Nov 14.

Laboratory of Biophysical Chemistry, University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1107/S1744309112044168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509963PMC
December 2012
12 Reads
15 Citations
0.570 Impact Factor

N- and o-glycosylation of a commercial bovine whey protein product.

J Agric Food Chem 2012 Dec 12;60(51):12553-64. Epub 2012 Dec 12.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen , Nijenborgh 7, NL-9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1021/jf304000bDOI Listing
December 2012
7 Reads
2 Citations
2.912 Impact Factor

Molecular characterization of ltp3 and ltp4, essential for C24-branched chain sterol-side-chain degradation in Rhodococcus rhodochrous DSM 43269.

Microbiology 2012 Dec 11;158(Pt 12):3054-62. Epub 2012 Oct 11.

Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, Groningen, The Netherlands.

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http://dx.doi.org/10.1099/mic.0.059501-0DOI Listing
December 2012
4 Reads
4 Citations
2.560 Impact Factor

The role of conserved inulosucrase residues in the reaction and product specificity of Lactobacillus reuteri inulosucrase.

FEBS J 2012 Oct 3;279(19):3612-3621. Epub 2012 Sep 3.

 Department of Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, The Netherlands Laboratory of Biophysical Chemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, The Netherlands.

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http://dx.doi.org/10.1111/j.1742-4658.2012.08721.xDOI Listing
October 2012
11 Reads
1 Citation
4.001 Impact Factor

Use of Wisteria floribunda agglutinin affinity chromatography in the structural analysis of the bovine lactoferrin N-linked glycosylation.

Biochim Biophys Acta 2012 Sep 2;1820(9):1444-55. Epub 2012 Jan 2.

Department of Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, NL-9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.bbagen.2011.12.014DOI Listing
September 2012
10 Reads
4 Citations

Structure and catalytic mechanism of 3-ketosteroid-Delta4-(5α)-dehydrogenase from Rhodococcus jostii RHA1 genome.

J Biol Chem 2012 Sep 24;287(37):30975-83. Epub 2012 Jul 24.

Laboratory of Biophysical Chemistry, University of Groningen, 9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M112.374306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438930PMC
September 2012
6 Reads
2 Citations
4.573 Impact Factor

Biochemical characterization of Aspergillus niger CfcI, a glycoside hydrolase family 18 chitinase that releases monomers during substrate hydrolysis.

Microbiology 2012 Aug 10;158(Pt 8):2168-79. Epub 2012 May 10.

Microbial Physiology Research Group, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1099/mic.0.054650-0DOI Listing
August 2012
8 Reads
4 Citations
2.560 Impact Factor

Enzymatic glycosylation of small molecules: challenging substrates require tailored catalysts.

Chemistry 2012 Aug 8;18(35):10786-801. Epub 2012 Aug 8.

University of Ghent, Centre for Industrial Biotechnology and Biocatalysis, Gent, Belgium.

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http://dx.doi.org/10.1002/chem.201103069DOI Listing
August 2012
3 Reads
22 Citations
5.731 Impact Factor

SapB and the rodlins are required for development of Streptomyces coelicolor in high osmolarity media.

FEMS Microbiol Lett 2012 Apr 24;329(2):154-9. Epub 2012 Feb 24.

Department of Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1111/j.1574-6968.2012.02517.xDOI Listing
April 2012
4 Reads
3 Citations
2.121 Impact Factor

Structural characterization of linear isomalto-/malto-oligomer products synthesized by the novel GTFB 4,6-α-glucanotransferase enzyme from Lactobacillus reuteri 121.

Glycobiology 2012 Apr 2;22(4):517-28. Epub 2011 Dec 2.

Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1093/glycob/cwr167DOI Listing
April 2012
7 Reads
8 Citations
3.150 Impact Factor

Structural features in the KshA terminal oxygenase protein that determine substrate preference of 3-ketosteroid 9α-hydroxylase enzymes.

J Bacteriol 2012 Jan 21;194(1):115-21. Epub 2011 Oct 21.

Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1128/JB.05838-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256619PMC
January 2012
9 Reads
8 Citations
2.810 Impact Factor

Enzymatic degradation of granular potato starch by Microbacterium aurum strain B8.A.

Appl Microbiol Biotechnol 2012 Jan 6;93(2):645-54. Epub 2011 Jul 6.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, 9747 AG, Groningen, The Netherlands.

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http://dx.doi.org/10.1007/s00253-011-3436-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257434PMC
January 2012
15 Reads
4 Citations
3.340 Impact Factor

4,6-α-glucanotransferase, a novel enzyme that structurally and functionally provides an evolutionary link between glycoside hydrolase enzyme families 13 and 70.

Appl Environ Microbiol 2011 Nov 23;77(22):8154-63. Epub 2011 Sep 23.

Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute-GBB, University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1128/AEM.05735-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3209003PMC
November 2011
14 Reads
14 Citations
3.670 Impact Factor

Cloning, overexpression, purification, crystallization and preliminary X-ray analysis of 3-ketosteroid Δ(4)-(5α)-dehydrogenase from Rhodococcus jostii RHA1.

Acta Crystallogr Sect F Struct Biol Cryst Commun 2011 Oct 30;67(Pt 10):1269-73. Epub 2011 Sep 30.

Laboratory of Biophysical Chemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1107/S1744309111028727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212380PMC
October 2011
7 Reads
2 Citations
0.570 Impact Factor

Crystal structure of inulosucrase from Lactobacillus: insights into the substrate specificity and product specificity of GH68 fructansucrases.

J Mol Biol 2011 Sep 23;412(1):80-93. Epub 2011 Jul 23.

Laboratory of Biophysical Chemistry, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Nijenborgh 7, 9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jmb.2011.07.031DOI Listing
September 2011
10 Reads
7 Citations
4.333 Impact Factor

Multiplicity of 3-Ketosteroid-9α-Hydroxylase enzymes in Rhodococcus rhodochrous DSM43269 for specific degradation of different classes of steroids.

J Bacteriol 2011 Aug 3;193(15):3931-40. Epub 2011 Jun 3.

Department of Microbiology, University of Groningen, AG Groningen, The Netherlands.

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http://dx.doi.org/10.1128/JB.00274-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147496PMC
August 2011
6 Reads
17 Citations
2.810 Impact Factor

Thermus thermophilus glycoside hydrolase family 57 branching enzyme: crystal structure, mechanism of action, and products formed.

J Biol Chem 2011 Feb 19;286(5):3520-30. Epub 2010 Nov 19.

Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, Kerklaan 30, 9751 NN Haren, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M110.179515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3030357PMC
February 2011
7 Reads
5 Citations
4.573 Impact Factor

Land use intensity controls actinobacterial community structure.

Microb Ecol 2011 Feb 5;61(2):286-302. Epub 2010 Oct 5.

Department of Microbial Ecology, Centre for Ecological and Evolutionary Studies, University of Groningen, Kerklaan 30, 9750RA Haren, the Netherlands.

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http://dx.doi.org/10.1007/s00248-010-9752-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232471PMC
February 2011
9 Reads
8 Citations
2.973 Impact Factor

Crystal structure of a 117 kDa glucansucrase fragment provides insight into evolution and product specificity of GH70 enzymes.

Proc Natl Acad Sci U S A 2010 Dec 30;107(50):21406-11. Epub 2010 Nov 30.

Laboratory of Biophysical Chemistry, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1073/pnas.1007531107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003066PMC
December 2010
14 Reads
29 Citations
9.810 Impact Factor

Metabolomic characterization of the salt stress response in Streptomyces coelicolor.

Appl Environ Microbiol 2010 Apr 26;76(8):2574-81. Epub 2010 Feb 26.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, 9751 NN Haren, Netherlands.

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http://dx.doi.org/10.1128/AEM.01992-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849216PMC
April 2010
5 Reads
16 Citations
3.670 Impact Factor

Inulin and levan synthesis by probiotic Lactobacillus gasseri strains: characterization of three novel fructansucrase enzymes and their fructan products.

Microbiology 2010 Apr 14;156(Pt 4):1264-74. Epub 2010 Jan 14.

Microbial Physiology Research Group, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands.

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http://dx.doi.org/10.1099/mic.0.036616-0DOI Listing
April 2010
8 Reads
5 Citations
2.560 Impact Factor

Engineering of cyclodextrin glucanotransferases and the impact for biotechnological applications.

Appl Microbiol Biotechnol 2010 Jan 18;85(4):823-35. Epub 2009 Sep 18.

Microbial Physiology, Groningen Biomolecular Sciences, and Biotechnology Institute (GBB), University of Groningen, Haren, The Netherlands.

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http://dx.doi.org/10.1007/s00253-009-2221-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2804789PMC
January 2010
6 Reads
13 Citations
3.340 Impact Factor

Cytochrome P450 125 (CYP125) catalyses C26-hydroxylation to initiate sterol side-chain degradation in Rhodococcus jostii RHA1.

Mol Microbiol 2009 Dec 15;74(5):1031-43. Epub 2009 Oct 15.

Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, PO Box 14, 9750 AA Haren, the Netherlands.

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http://dx.doi.org/10.1111/j.1365-2958.2009.06915.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218833PMC
December 2009
11 Reads
37 Citations
4.420 Impact Factor

Screening of lactic acid bacteria from Indonesia reveals glucansucrase and fructansucrase genes in two different Weissella confusa strains from soya.

FEMS Microbiol Lett 2009 Nov 28;300(1):131-8. Epub 2009 Aug 28.

Department of Pharmacy, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok, Indonesia.

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http://dx.doi.org/10.1111/j.1574-6968.2009.01772.xDOI Listing
November 2009
6 Reads
8 Citations
2.121 Impact Factor

Attachment of Streptomyces coelicolor is mediated by amyloidal fimbriae that are anchored to the cell surface via cellulose.

Mol Microbiol 2009 Sep 11;73(6):1128-40. Epub 2009 Aug 11.

Groningen Biomolecular Sciences and Biotechnology Institute (GBB), Department of Microbiology, University of Groningen, Haren, The Netherlands.

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http://dx.doi.org/10.1111/j.1365-2958.2009.06838.xDOI Listing
September 2009
7 Reads
32 Citations
4.420 Impact Factor

The evolution of cyclodextrin glucanotransferase product specificity.

Appl Microbiol Biotechnol 2009 Aug 15;84(1):119-33. Epub 2009 Apr 15.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute, Centre for Carbohydrate Bioprocessing, University of Groningen, Kerklaan 30, 9751 NN Haren, the Netherlands.

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http://dx.doi.org/10.1007/s00253-009-1988-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714454PMC
August 2009
6 Reads
8 Citations
3.340 Impact Factor

Directed evolution of enzymes: Library screening strategies.

IUBMB Life 2009 Mar;61(3):222-8

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Haren, The Netherlands.

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http://dx.doi.org/10.1002/iub.165DOI Listing
March 2009
6 Reads
12 Citations
3.143 Impact Factor

Structural characterization of bioengineered alpha-D-glucans produced by mutant glucansucrase GTF180 enzymes of Lactobacillus reuteri strain 180.

Biomacromolecules 2009 Mar;10(3):580-8

Department of Bio-Organic Chemistry, Bijvoet Center, Utrecht University, Utrecht, The Netherlands.

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http://dx.doi.org/10.1021/bm801240rDOI Listing
March 2009
6 Reads
11 Citations
5.750 Impact Factor

NepA is a structural cell wall protein involved in maintenance of spore dormancy in Streptomyces coelicolor.

Mol Microbiol 2009 Mar 13;71(6):1591-603. Epub 2009 Feb 13.

Groningen Biomolecular Sciences and Biotechnology Institute, Department of Microbiology, University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands.

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http://dx.doi.org/10.1111/j.1365-2958.2009.06633.xDOI Listing
March 2009
6 Reads
10 Citations
4.420 Impact Factor

Starch and alpha-glucan acting enzymes, modulating their properties by directed evolution.

J Biotechnol 2009 Mar 7;140(3-4):184-93. Epub 2009 Feb 7.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute, Centre for Carbohydrate Bioprocessing, University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands.

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http://dx.doi.org/10.1016/j.jbiotec.2009.01.020DOI Listing
March 2009
6 Reads
11 Citations
2.871 Impact Factor

Hybrid reuteransucrase enzymes reveal regions important for glucosidic linkage specificity and the transglucosylation/hydrolysis ratio.

FEBS J 2008 Dec;275(23):6002-10

Centre for Carbohydrate Bioprocessing, TNO-University of Groningen, Haren, The Netherlands.

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http://dx.doi.org/10.1111/j.1742-4658.2008.06729.xDOI Listing
December 2008
6 Reads
3 Citations
4.001 Impact Factor

The actinobacterial mce4 locus encodes a steroid transporter.

J Biol Chem 2008 Dec 27;283(51):35368-74. Epub 2008 Oct 27.

Department of Microbiology and Immunology, Life Sciences Institute, University of British Columbia, Vancouver V6T 1Z3, Canada.

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http://dx.doi.org/10.1074/jbc.M805496200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5218832PMC
December 2008
11 Reads
58 Citations
4.573 Impact Factor

Antibiotic overproduction in Streptomyces coelicolor A3 2 mediated by phosphofructokinase deletion.

J Biol Chem 2008 Sep 7;283(37):25186-99. Epub 2008 Jul 7.

Center for Microbial Biotechnology, BioCentrum-DTU, Technical University of Denmark, 2800 Kongens Lyngby, Denmark.

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http://dx.doi.org/10.1074/jbc.M803105200DOI Listing
September 2008
4 Reads
31 Citations
4.573 Impact Factor

Structural analysis of bioengineered alpha-D-glucan produced by a triple mutant of the Glucansucrase GTF180 enzyme from Lactobacillus reuteri strain 180: generation of (alpha1-->4) linkages in a native (1-->3)(1-->6)-alpha-D-glucan.

Biomacromolecules 2008 Aug 11;9(8):2251-8. Epub 2008 Jul 11.

Department of Bio-Organic Chemistry, Bijvoet Center, Utrecht University, 3584 CH Utrecht, The Netherlands.

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http://dx.doi.org/10.1021/bm800410wDOI Listing
August 2008
15 Reads
6 Citations
5.750 Impact Factor

Elimination of competing hydrolysis and coupling side reactions of a cyclodextrin glucanotransferase by directed evolution.

Biochem J 2008 Aug;413(3):517-25

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands.

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http://dx.doi.org/10.1042/BJ20080353DOI Listing
August 2008
6 Reads
9 Citations
4.400 Impact Factor

The probiotic Lactobacillus johnsonii NCC 533 produces high-molecular-mass inulin from sucrose by using an inulosucrase enzyme.

Appl Environ Microbiol 2008 Jun 11;74(11):3426-33. Epub 2008 Apr 11.

Centre for Carbohydrate Bioprocessing, TNO-University of Groningen, PO Box 14, 9750 AA Haren, The Netherlands.

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http://dx.doi.org/10.1128/AEM.00377-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2423029PMC
June 2008
6 Reads
5 Citations
3.670 Impact Factor

Aspergillus niger genome-wide analysis reveals a large number of novel alpha-glucan acting enzymes with unexpected expression profiles.

Mol Genet Genomics 2008 Jun 5;279(6):545-61. Epub 2008 Mar 5.

Clusius Laboratory, Molecular Microbiology and Kluyver Centre for Genomics of Industrial Fermentations, Institute of Biology Leiden, Leiden University, Leiden, The Netherlands.

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http://dx.doi.org/10.1007/s00438-008-0332-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2413074PMC
June 2008
12 Reads
31 Citations

Engineering the glucansucrase GTFR enzyme reaction and glycosidic bond specificity: toward tailor-made polymer and oligosaccharide products.

Biochemistry 2008 Jun;47(25):6678-84

Department of Carbohydrate Technology, University of Braunschweig, Braunschweig, Germany.

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http://dx.doi.org/10.1021/bi800563rDOI Listing
June 2008
5 Reads
9 Citations
3.020 Impact Factor

Actinomycete integrative and conjugative elements.

Antonie Van Leeuwenhoek 2008 Jun 4;94(1):127-43. Epub 2008 Jun 4.

Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands.

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http://dx.doi.org/10.1007/s10482-008-9255-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440964PMC
June 2008
30 Reads
22 Citations
1.810 Impact Factor

Actinomycete integrative and conjugative pMEA-like elements of Amycolatopsis and Saccharopolyspora decoded.

Plasmid 2008 May 3;59(3):202-16. Epub 2008 Mar 3.

Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands.

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http://dx.doi.org/10.1016/j.plasmid.2008.01.003DOI Listing
May 2008
11 Reads
4 Citations
1.580 Impact Factor

Structural analysis of the alpha-D-glucan (EPS180) produced by the Lactobacillus reuteri strain 180 glucansucrase GTF180 enzyme.

Carbohydr Res 2008 May 7;343(7):1237-50. Epub 2008 Feb 7.

Bijvoet Center, Department of Bio-Organic Chemistry, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.carres.2008.01.042DOI Listing
May 2008
8 Reads
13 Citations
1.930 Impact Factor

Evolution toward small molecule inhibitor resistance affects native enzyme function and stability, generating acarbose-insensitive cyclodextrin glucanotransferase variants.

J Biol Chem 2008 Apr 18;283(16):10727-34. Epub 2008 Feb 18.

Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute, Centre for Carbohydrate Bioprocessing, University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M709287200DOI Listing
April 2008
12 Reads
3 Citations
4.570 Impact Factor

3-Keto-5alpha-steroid Delta(1)-dehydrogenase from Rhodococcus erythropolis SQ1 and its orthologue in Mycobacterium tuberculosis H37Rv are highly specific enzymes that function in cholesterol catabolism.

Biochem J 2008 Mar;410(2):339-46

Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, PO Box 14, 9750 AA Haren, The Netherlands.

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http://dx.doi.org/10.1042/BJ20071130DOI Listing
March 2008
42 Reads
28 Citations
4.400 Impact Factor

Purification, crystallization and preliminary X-ray analysis of a thermostable glycoside hydrolase family 43 beta-xylosidase from Geobacillus thermoleovorans IT-08.

Acta Crystallogr Sect F Struct Biol Cryst Commun 2007 Nov 24;63(Pt 11):932-5. Epub 2007 Oct 24.

Department of Chemistry, Faculty of Mathematics and Natural Sciences, Airlangga University, Kampus C Unair, Jl. Mulyorejo, Surabaya 60115, Indonesia.

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http://dx.doi.org/10.1107/S1744309107046015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2339754PMC
November 2007
7 Reads
3 Citations
0.570 Impact Factor

Conversion of a cyclodextrin glucanotransferase into an alpha-amylase: assessment of directed evolution strategies.

Biochemistry 2007 Oct 8;46(39):11216-22. Epub 2007 Sep 8.

Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands.

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http://dx.doi.org/10.1021/bi701160hDOI Listing
October 2007
11 Reads
7 Citations
3.020 Impact Factor

Prevalence and distribution of nucleotide sequences typical for pMEA-like accessory genetic elements in the genus Amycolatopsis.

FEMS Microbiol Ecol 2007 Aug 29;61(2):285-94. Epub 2007 May 29.

Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Haren, The Netherlands.

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http://dx.doi.org/10.1111/j.1574-6941.2007.00334.xDOI Listing
August 2007
10 Reads
2 Citations
3.570 Impact Factor

Three-way stabilization of the covalent intermediate in amylomaltase, an alpha-amylase-like transglycosylase.

J Biol Chem 2007 Jun 9;282(23):17242-9. Epub 2007 Apr 9.

Laboratory of Biophysical Chemistry, University of Groningen, Nijenborgh 4, 9747 AG Groningen, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M701444200DOI Listing
June 2007
11 Reads
20 Citations
4.570 Impact Factor

Identification of acceptor substrate binding subsites +2 and +3 in the amylomaltase from Thermus thermophilus HB8.

Biochemistry 2007 May 4;46(17):5261-9. Epub 2007 Apr 4.

Centre for Carbohydrate Bioprocessing TNO, University of Groningen, 9751 NN Haren, The Netherlands.

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http://dx.doi.org/10.1021/bi602408jDOI Listing
May 2007
11 Reads
8 Citations
3.020 Impact Factor

Molecular and biochemical characterization of a novel intracellular invertase from Aspergillus niger with transfructosylating activity.

Eukaryot Cell 2007 Apr 9;6(4):674-81. Epub 2007 Feb 9.

Department of Microbiology, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Kerklaan 30, 9751 NN Haren, The Netherlands.

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http://dx.doi.org/10.1128/EC.00361-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1865650PMC
April 2007
28 Reads
10 Citations

Top co-authors

Johannis P Kamerling
Johannis P Kamerling

Groningen Biomolecular Sciences and Biotechnology Institute (GBB)

24
Tjaard Pijning
Tjaard Pijning

Groningen Biomolecular Sciences and Biotechnology Institute (GBB)

23
Slavko Kralj
Slavko Kralj

Jožef Stefan Institute

20
Justyna M Dobruchowska
Justyna M Dobruchowska

Groningen Biomolecular Sciences and Biotechnology Institute (GBB)

20
Gerrit J Gerwig
Gerrit J Gerwig

Utrecht University / University of Groningen

18
Hans Leemhuis
Hans Leemhuis

Groningen Biomolecular Sciences and Biotechnology Institute (GBB)

17
Xiangfeng Meng
Xiangfeng Meng

The Stomatological Hospital Affiliated Medical School

12
Bauke W Dijkstra
Bauke W Dijkstra

Laboratory of Biophysical Chemistry

11