Publications by authors named "Luana Lionetto"

88Publications

Increased kynurenine-to-tryptophan ratio in the serum of patients infected with SARS-CoV2: An observational cohort study.

Biochim Biophys Acta Mol Basis Dis 2020 Dec 16;1867(3):166042. Epub 2020 Dec 16.

Department of Neurosciences, Mental Health and Sensory Organs (NESMOS), Sapienza University, Rome, Italy; Laboratory of Clinical Biochemistry, Advanced Molecular Diagnostic Unit, Sant'Andrea University Hospital, Rome, Italy. Electronic address:

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December 2020

Inter-individual variation in CYP2A6 activity and chronic obstructive pulmonary disease in smokers: Perspectives for an early predictive marker.

Biochim Biophys Acta Mol Basis Dis 2021 Jan 19;1867(1):165990. Epub 2020 Oct 19.

Laboratory of Clinical Biochemistry, Sant'Andrea Hospital, Rome, Italy; Department of Neurosciences, Mental Health and Sensory Organs (NESMOS), Sapienza University, Rome, Italy. Electronic address:

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January 2021

Persistent Post-Traumatic Headache and Migraine: Pre-Clinical Comparisons.

Int J Environ Res Public Health 2020 04 9;17(7). Epub 2020 Apr 9.

Mass Spectrometry Lab-Clinical Biochemistry Unit, Sant'Andrea University Hospital, 00189 Rome, Italy.

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April 2020

Ubrogepant for the treatment of migraine.

Expert Opin Pharmacother 2020 May 3;21(7):755-759. Epub 2020 Feb 3.

Mass Spectrometry Lab-Clinical Biochemistry Unit, Sant'Andrea University Hospital , Rome, Italy.

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May 2020

Profiling lasmiditan as a treatment option for migraine.

Expert Opin Pharmacother 2020 Feb 25;21(2):147-153. Epub 2019 Nov 25.

Mass Spectrometry Laboratory Unit, Sant'Andrea University Hospital, Rome, Italy.

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February 2020

Fremanezumab for the preventive treatment of migraine in adults.

Expert Rev Clin Pharmacol 2019 Aug 26;12(8):741-748. Epub 2019 Jun 26.

f Department of Clinical and Molecular Medicine, Sapienza University of Rome , Rome , Italy.

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August 2019

Urinary and exhaled biomarkers of exercise-induced bronchoconstriction in atopic asthmatic children.

Pediatr Pulmonol 2019 09 19;54(9):1447-1456. Epub 2019 Jun 19.

Pediatric Unit Sant'Andrea Hospital, NESMOS Department, Faculty of Medicine and Psychology, Sapienza University, Rome, Italy.

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September 2019

Migraine and cluster headache show impaired neurosteroids patterns.

J Headache Pain 2019 May 27;20(1):61. Epub 2019 May 27.

Department of Clinical and Molecular Medicine, Sapienza University and Regional Referral Headache Centre, Sant'Andrea Hospital, via di Grottarossa 1035-1039, 00189, Rome, Italy.

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May 2019

DHA Oral Supplementation Modulates Serum Epoxydocosapentaenoic Acid (EDP) Levels in Breast Cancer Patients.

Oxid Med Cell Longev 2019 5;2019:1280987. Epub 2019 Mar 5.

Department of Translational and Precision Medicine, Sapienza University of Rome, v.le dell'Università 37, 00185 Rome, Italy.

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July 2019

Serum xanthurenic acid levels: Reduced in subjects at ultra high risk for psychosis.

Schizophr Res 2019 06 2;208:465-466. Epub 2019 Mar 2.

International Mood & Psychotic Disorders Research Consortium, McLean Hospital, Belmont, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.

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June 2019

How do you choose the appropriate migraine pharmacotherapy for an elderly person?

Expert Opin Pharmacother 2019 01 7;20(1):1-3. Epub 2018 Nov 7.

c Laboratory of Clinical Chemistry , Sant'Andrea Hospital , Rome , Italy.

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January 2019

Pharmacogenetic considerations for migraine therapies.

Expert Opin Drug Metab Toxicol 2018 Nov 1;14(11):1161-1167. Epub 2018 Nov 1.

d Department of Clinical and Molecular Medicine , Sapienza University of Rome , Rome , Italy.

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November 2018

Lacosamide in bipolar disorder: A 30-day comparison to a retrospective control group treated with other antiepileptics.

Psychiatry Clin Neurosci 2018 Dec 19;72(12):864-875. Epub 2018 Oct 19.

NESMOS Department, School of Medicine and Psychology, Sapienza University, Rome, Italy.

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December 2018

Lacosamide in bipolar disorder: A 30-day comparison to a retrospective control group treated with other antiepileptics.

Psychiatry Clin Neurosci 2018 Dec 19;72(12):864-875. Epub 2018 Oct 19.

NESMOS Department, School of Medicine and Psychology, Sapienza University, Rome, Italy.

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December 2018

Can IDO activity predict primary resistance to anti-PD-1 treatment in NSCLC?

J Transl Med 2018 08 6;16(1):219. Epub 2018 Aug 6.

Department of Clinical and Molecular Medicine, Sant'Andrea Hospital, Sapienza University of Rome, Via di Grottarossa 1035-1037, 00189, Rome, Italy.

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August 2018

Changing the Approach to Anticoagulant Therapy in Older Patients with Multimorbidity Using a Precision Medicine Approach.

Int J Environ Res Public Health 2018 08 2;15(8). Epub 2018 Aug 2.

Department of Clinical and Molecular Medicine, Azienda Ospedaliera Universitaria S. Andrea, via di Grottarossa 1035/1039, 00189 Rome, Italy.

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August 2018

Maternal exposure to endocrine disruptors and placental transmission: a pilot study.

Gynecol Endocrinol 2018 Nov 29;34(11):1001-1004. Epub 2018 May 29.

d NESMOS Department , S. Andrea Hospital, University of Rome Sapienza , Rome , Italy.

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November 2018

A Critical Evaluation on MOH Current Treatments.

Curr Treat Options Neurol 2017 Aug 15;19(9):32. Epub 2017 Aug 15.

Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy.

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August 2017

Changes in serum levels of kynurenine metabolites in paediatric patients affected by ADHD.

Eur Child Adolesc Psychiatry 2017 Dec 19;26(12):1433-1441. Epub 2017 May 19.

NESMOS Department, School of Medicine and Psychology, Sant'Andrea Hospital, Sapienza University, Via di Grottarossa 1035-1039, 00189, Rome, Italy.

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December 2017

A nomogram to predict 5-fluorouracil toxicity: when pharmacogenomics meets the patient.

Anticancer Drugs 2017 06;28(5):551-556

Departments of aClinical and Molecular Medicine bRadiological Oncological and Pathological Sciences cNeurosciences, Mental Health and Sensory Organs (NESMOS), 'Sapienza' University of Rome dDepartment of Medical Oncology, Sant'Andrea Hospital eLaboratory of Medical Physics and Expert Systems, Regina Elena National Cancer Institute fIstituto Dermopatico dell'Immacolata-IRCCS, Rome, Italy.

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June 2017

Personalised Healthcare: The DiMA Clinical Model.

Curr Pharm Biotechnol 2017 ;18(3):242-252

DiMA (Advanced Molecular Diagnosis), Department of Medical-Surgical Sciences and Translational Medicine, Sant'Andrea Hospital - Sapienza University of Rome, Via di Grottarossa, 00189 Rome. Italy.

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December 2017

Integrated OMICS tools for personalised medicine.

J Headache Pain 2015 Dec;16(Suppl 1):A9

Advanced Molecular Diagnostics Unit, Sant'Andrea Hospital, Sapienza University of Roma, Rome, Italy.

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December 2015

Choosing the safest acute combination therapy during prophylactic treatment: pharmacokinetic and pharmacodynamic considerations.

J Headache Pain 2015 Dec;16(Suppl 1):A36

Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy.

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December 2015

O066. Kynurenine pathway metabolites in cluster headache.

J Headache Pain 2015 Dec;16(Suppl 1):A87

Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy.

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December 2015

Lasmiditan for the treatment of migraine.

Expert Opin Investig Drugs 2017 Feb;26(2):227-234

f Department of Clinical and Molecular Medicine , Sapienza University , Rome , Italy.

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February 2017

5-Fluorouracil degradation rate could predict toxicity in stages II-III colorectal cancer patients undergoing adjuvant FOLFOX.

Anticancer Drugs 2017 03;28(3):322-326

Departments of aClinical and Molecular Medicine bNeurosciences, Mental Health and Sensory Organs (NESMOS), 'Sapienza' University of Rome Departments of cMedical Oncology dGeneral Surgery, Sant'Andrea Hospital eIstituto Dermopatico dell'Immacolata-IRCCS, Rome, Italy.

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March 2017

Hedonic sensitivity to natural rewards is affected by prenatal stress in a sex-dependent manner.

Addict Biol 2016 11 26;21(6):1072-1085. Epub 2015 May 26.

International Associated Laboratory (LIA) 'Prenatal Stress and Neurodegenerative Diseases', UMR8576 University Lille 1/CNRS, France.

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November 2016

Eletriptan in the management of acute migraine: an update on the evidence for efficacy, safety, and consistent response.

Ther Adv Neurol Disord 2016 Sep 3;9(5):414-23. Epub 2016 Jun 3.

Department of Molecular Medicine, Sant'Andrea Medical Center, Sapienza University of Rome, Italy Regional Referral Headache Center, Sant'Andrea Hospital, Rome, Italy.

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September 2016

The TYMS-TSER polymorphism is associated with toxicity of low-dose capecitabine in patients with advanced gastrointestinal cancer.

Anticancer Drugs 2016 11;27(10):1044-9

aClinical and Molecular Medicine Department bAdvanced Molecular Diagnostics Unit cDepartment of Neurosciences, Mental Health and Sensory Organs, Sant'Andrea Hospital, Sapienza University dGenetic Epidemiology Unit, National Centre for Epidemiology, Surveillance and Health Promotion, National Institute of Health, Rome, Italy.

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November 2016

Cinnabarinic acid and xanthurenic acid: Two kynurenine metabolites that interact with metabotropic glutamate receptors.

Neuropharmacology 2017 Jan 21;112(Pt B):365-372. Epub 2016 Jun 21.

I.R.C.C.S. Neuromed, Pozzilli, Italy; Department of Physiology and Pharmacology, Sapienza University, Rome, Italy.

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January 2017

Chronic migraine treatment: from OnabotulinumtoxinA onwards.

Expert Rev Neurother 2016 10 4;16(10):1217-27. Epub 2016 Jul 4.

a Department of Clinical and Molecular Medicine , Sapienza University , Rome , Italy.

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October 2016

Acute, transitional and long-term cluster headache treatment: pharmacokinetic issues.

Expert Opin Drug Metab Toxicol 2016 Sep 27;12(9):1011-20. Epub 2016 Jun 27.

c Department of Molecular Medicine, Sant'Andrea Medical Center , Sapienza University of Rome , Rome , Italy.

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September 2016

Altered intestinal permeability in patients with relapsing-remitting multiple sclerosis: A pilot study.

Mult Scler 2017 Mar 11;23(3):442-446. Epub 2016 Jul 11.

Center for Experimental Neurological Therapies, Sant'Andrea Hospital, Department of Neurosciences, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy.

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March 2017

Altered intestinal permeability in patients with relapsing-remitting multiple sclerosis: A pilot study.

Mult Scler 2017 Mar 11;23(3):442-446. Epub 2016 Jul 11.

Center for Experimental Neurological Therapies, Sant'Andrea Hospital, Department of Neurosciences, Mental Health and Sensory Organs (NESMOS), Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy.

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March 2017

Altered kynurenine pathway metabolites in serum of chronic migraine patients.

J Headache Pain 2015 29;17:47. Epub 2016 Apr 29.

Department of Molecular Medicine, Sant'Andrea Medical Center, Sapienza University, Via di Grottarossa 1035-1039, Rome, 00189, Italy.

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September 2016

Altered serum levels of kynurenine metabolites in patients affected by cluster headache.

J Headache Pain 2015 22;17:27. Epub 2016 Mar 22.

Department of Molecular Medicine, Sant'Andrea Medical Center, Sapienza University of Rome, Via di Grottarossa 1035-1039, Rome, 00189, Italy.

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September 2016

Choosing the safest acute therapy during chronic migraine prophylactic treatment: pharmacokinetic and pharmacodynamic considerations.

Expert Opin Drug Metab Toxicol 2016 9;12(4):399-406. Epub 2016 Mar 9.

d Department of Clinical and Molecular Medicine , Sapienza University of Rome , Rome , Italy.

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January 2017

A two years open-label prospective study of OnabotulinumtoxinA 195 U in medication overuse headache: a real-world experience.

J Headache Pain 2015 21;17. Epub 2016 Jan 21.

Department of Clinical and Molecular Medicine, Sapienza University, Rome, Italy.

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September 2016

OnabotulinumtoxinA 155 U in medication overuse headache: a two years prospective study.

Springerplus 2015 30;4:826. Epub 2015 Dec 30.

Department of Clinical and Molecular Medicine, Sapienza University, Rome, Italy ; Regional Referral Headache Centre, Sant'Andrea Hospital, Rome, Italy.

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January 2016

Impairment of left ventricular function early in treatment with clozapine: a preliminary study.

Int Clin Psychopharmacol 2015 Sep;30(5):282-9

aDepartment of Psychiatry, Harvard Medical School, Boston bBipolar & Psychotic Disorders Program, McLean Hospital, Belmont, Massachusetts, USA Departments of cPsychiatry dCardiology eAdvanced Molecular Diagnostics (Di.M.A), Sant'Andrea Medical Center, Sapienza University of Rome, Rome, Italy.

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September 2015

Intestinal permeability in children with recurrent respiratory and gastrointestinal symptoms.

J Paediatr Child Health 2015 Dec 4;51(12):1214-20. Epub 2015 Jun 4.

Pediatric Unit Sant'Andrea Hospital, NESMOS Department, Faculty of Medicine and Psychology, 'Sapienza' University, Rome, Italy.

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December 2015

Fathoming the kynurenine pathway in migraine: why understanding the enzymatic cascades is still critically important.

Intern Emerg Med 2015 Jun 24;10(4):413-21. Epub 2015 Feb 24.

Psychiatric Unit, Neurosciences, Mental Health and Sensory Organs (NESMOS) Department, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy.

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June 2015

The therapeutic potential of novel anti-migraine acute therapies.

Expert Opin Investig Drugs 2015 Feb 13;24(2):141-4. Epub 2014 Nov 13.

Sapienza University, Department of Clinical and Molecular Medicine , Rome , Italy

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February 2015

Pharmacogenetic insights into migraine treatment in children.

Pharmacogenomics 2014 Aug;15(11):1539-50

NESMOS Department, Sapienza University of Rome, Rome, Italy.

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August 2014

Sodium channel antagonists for the treatment of migraine.

Expert Opin Pharmacother 2014 Aug 18;15(12):1697-706. Epub 2014 Jun 18.

Sapienza University of Rome, NESMOS Department , Rome , Italy.

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August 2014

Treatment of menstrual migraine: utility of control of related mood disturbances.

Expert Rev Neurother 2014 May 7;14(5):493-502. Epub 2014 Apr 7.

Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy.

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May 2014

Urinary concentration of 8-isoprostane as marker of severity of pediatric OSAS.

Sleep Breath 2014 Dec 17;18(4):723-9. Epub 2014 Jan 17.

Neuroscience, Mental Health and Sense Organs Department, Sleep Disorder Centre, Faculty of Medicine and Psychology, "La Sapienza" University, Rome, Italy,

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December 2014

Sumatriptan in clinical practice: effectiveness in migraine and the problem of psychiatric comorbidity.

Expert Opin Pharmacother 2014 Feb 9;15(3):303-5. Epub 2013 Nov 9.

Sapienza University, Department of Clinical and Molecular Medicine , Rome , Italy.

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February 2014

The omics in migraine.

J Headache Pain 2013 Jul 1;14:55. Epub 2013 Jul 1.

Sant'Andrea Hospital, Advanced Molecular Diagnostics Unit, Via di Grottarossa 1035 - 1039, Rome 00189, Italy.

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July 2013

Pharmacokinetic evaluation of almotriptan for the treatment of migraines.

Expert Opin Drug Metab Toxicol 2013 May 9;9(5):637-44. Epub 2013 Apr 9.

Sapienza University of Rome and Regional Referral Headache Centre, Sant'Andrea Hospital, Department of Clinical and Molecular Medicine, Rome, Italy.

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May 2013

Deciphering the task of N-acetyl aspartate in migraine.

Expert Rev Neurother 2012 Sep;12(9):1057-9

NESMOS Department, Advanced Molecular Diagnostic Unit, Sapienza University, Sant'Andrea Hospital, Rome, Italy.

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September 2012

Sumatriptan succinate : pharmacokinetics of different formulations in clinical practice.

Expert Opin Pharmacother 2012 Nov 26;13(16):2369-80. Epub 2012 Sep 26.

NESMOS Department, Advanced Molecular Diagnostic Unit, Sapienza University, Sant'Andrea Hospital, Via di Grottarossa 1035,Rome, Italy.

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November 2012

Emerging treatment for chronic migraine and refractory chronic migraine.

Expert Opin Emerg Drugs 2012 Sep 3;17(3):393-406. Epub 2012 Aug 3.

Sapienza University and Advanced Molecular Diagnostic Unit, Sant'Andrea Hospital, NESMOS Department, Rome, Italy.

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September 2012

Pharmacokinetic evaluation of zolmitriptan for the treatment of migraines.

Expert Opin Drug Metab Toxicol 2012 Aug 5;8(8):1043-50. Epub 2012 Jul 5.

Sapienza University, Sant'Andrea Hospital, Advanced Molecular Diagnostic Unit, NESMOS Department, Rome, Italy.

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August 2012

Treatment of perimenstrual migraine with triptans: an update.

Curr Pain Headache Rep 2012 Oct;16(5):445-51

Sapienza University, Advanced Molecular Diagnostic Unit, NESMOS Department, Sant'Andrea Hospital, Rome, Italy.

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October 2012

CGRP receptor antagonists: an expanding drug class for acute migraine?

Expert Opin Investig Drugs 2012 Jun 19;21(6):807-18. Epub 2012 Apr 19.

Sapienza University of Rome and Regional Referral Headache Centre, Sant'Andrea Hospital, Department of Clinical and Molecular Medicine, Via di Grottarossa 1035-1039, 00189, Rome, Italy.

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June 2012

An improved simple LC-MS/MS method for the measurement of serum aripiprazole and its major metabolite.

J Pharm Biomed Anal 2012 Mar 14;62:135-9. Epub 2012 Jan 14.

NESMOS (Neuroscience, Mental Health, and Sensory Organs) Department, School of Medicine and Psychology, Sapienza University, Sant'Andrea Hospital, Rome,

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March 2012

High-performance liquid chromatography-tandem mass spectrometry method for simultaneous quantification of carbamazepine, oxcarbazepine, and their main metabolites in human serum.

Ther Drug Monit 2012 Feb;34(1):53-8

Department of Neurosciences, Mental Health and Sensory Organs and UOD Diagnostica Molecolare Avanzata-Azienda Ospedaliera Sant'Andrea, University Sapienza of Rome, Rome, Italy.

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February 2012

Pharmacokinetic evaluation of frovatriptan.

Expert Opin Drug Metab Toxicol 2011 Nov 20;7(11):1449-58. Epub 2011 Sep 20.

Sapienza University, Regional Referral Headache Center, School of Health Sciences, Department of Medical and Molecular Sciences, Rome, Italy.

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November 2011

A liquid chromatography-tandem mass spectrometry method for the determination of 5-Fluorouracil degradation rate by intact peripheral blood mononuclear cells.

Ther Drug Monit 2009 Aug;31(4):482-8

Dipartimento di Scienze Biochimiche, UOD Diagnostica Molecolare Avanzata, Azienda Ospedaliera Sant'Andrea, II Facoltà di Medicina e Chirurgia, Sapienza Università di Roma, Rome, Italy.

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August 2009

Serum levels of risperidone and its metabolite, 9-hydroxyrisperidone: correlation between drug concentration and clinical response.

Ther Drug Monit 2009 Aug;31(4):475-81

Dipartimento di Scienze Biochimiche A. Rossi Fanelli, Diagnostica Molecolare Avanzata, Azienda Ospedaliera Sant'Andrea, II Facoltà di Medicina e Chirurgia, Sapienza Università di Roma, Rome, Italy.

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August 2009

HPLC-mass spectrometry method for quantitative detection of neuroendocrine tumor markers: vanillylmandelic acid, homovanillic acid and 5-hydroxyindoleacetic acid.

Clin Chim Acta 2008 Dec 8;398(1-2):53-6. Epub 2008 Aug 8.

UO Diagnostica Molecolare Avanzata, Azienda Ospedaliera Sant'Andrea, Dipartimento di Scienze Biochimiche "A. Rossi Fanelli", II Facoltà di Medicina e Chirurgia, Università La Sapienza, Rome, Italy.

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December 2008

A liquid chromatography/mass spectrometry method for the evaluation of intestinal permeability.

Clin Biochem 2008 Jul 11;41(10-11):887-92. Epub 2008 Apr 11.

Dipartimento di Scienze Biochimiche - Unità di Diagnostica Molecolare Avanzata, Azienda Ospedaliera Sant'Andrea, II Facoltà di Medicina e Chirurgia, Sapienza Università di Roma, Via di Grottarossa, 1035, 00189 Rome, Italy.

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July 2008