Lovelace J Luquette

Lovelace J Luquette

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Lovelace J Luquette

Lovelace J Luquette

Publications by authors named "Lovelace J Luquette"

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21Publications

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Identification of somatic mutations in single cell DNA-seq using a spatial model of allelic imbalance.

Nat Commun 2019 Aug 29;10(1):3908. Epub 2019 Aug 29.

Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41467-019-11857-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6715686PMC
August 2019

Detecting Somatic Mutations in Normal Cells.

Trends Genet 2018 07 3;34(7):545-557. Epub 2018 May 3.

Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA; Division of Genetics, Brigham and Women's Hospital, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tig.2018.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029698PMC
July 2018

A Pan-Cancer Compendium of Genes Deregulated by Somatic Genomic Rearrangement across More Than 1,400 Cases.

Cell Rep 2018 07;24(2):515-527

Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.06.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092947PMC
July 2018

A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations.

Cancer Cell 2017 06 18;31(6):820-832.e3. Epub 2017 May 18.

Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502825PMC
June 2017

Somatic mutation in single human neurons tracks developmental and transcriptional history.

Science 2015 Oct;350(6256):94-98

Division of Genetics and Genomics, Manton Center for Orphan Disease, and Howard Hughes Medical Institute, Boston Children's Hospital, Boston, MA, USA; Departments of Neurology and Pediatrics, Harvard Medical School, Boston, MA, USA; and Broad Institute of MIT and Harvard, Cambridge, MA, USA.

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http://dx.doi.org/10.1126/science.aab1785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664477PMC
October 2015

COSMOS: Python library for massively parallel workflows.

Bioinformatics 2014 Oct 30;30(20):2956-8. Epub 2014 Jun 30.

Center for Biomedical Informatics, Harvard Medical School, 10 Shattuck Street, Boston, MA 02115, Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA and Department of Biology, Mohammed V University-Agal, 4 Ibn Battouta Avenue, Rabat B.P:1014RP, Morocco Center for Biomedical Informatics, Harvard Medical School, 10 Shattuck Street, Boston, MA 02115, Department of Pathology, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA and Department of Biology, Mohammed V University-Agal, 4 Ibn Battouta Avenue, Rabat B.P:1014RP, Morocco.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btu385DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184253PMC
October 2014

Impact of sequencing depth in ChIP-seq experiments.

Nucleic Acids Res 2014 May 5;42(9):e74. Epub 2014 Mar 5.

Center for Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA Division of Genetics, Brigham and Women's Hospital & Harvard Medical School, Boston, MA 02115, USA Informatics Program, Children's Hospital, Boston, MA 02115, USA

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http://nar.oxfordjournals.org/content/42/9/e74.full.pdf
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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gku178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027199PMC
May 2014

An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

Authors:
Catherine A Brownstein Alan H Beggs Nils Homer Barry Merriman Timothy W Yu Katherine C Flannery Elizabeth T DeChene Meghan C Towne Sarah K Savage Emily N Price Ingrid A Holm Lovelace J Luquette Elaine Lyon Joseph Majzoub Peter Neupert David McCallie Peter Szolovits Huntington F Willard Nancy J Mendelsohn Renee Temme Richard S Finkel Sabrina W Yum Livija Medne Shamil R Sunyaev Ivan Adzhubey Christopher A Cassa Paul I W de Bakker Hatice Duzkale Piotr Dworzyński William Fairbrother Laurent Francioli Birgit H Funke Monica A Giovanni Robert E Handsaker Kasper Lage Matthew S Lebo Monkol Lek Ignaty Leshchiner Daniel G MacArthur Heather M McLaughlin Michael F Murray Tune H Pers Paz P Polak Soumya Raychaudhuri Heidi L Rehm Rachel Soemedi Nathan O Stitziel Sara Vestecka Jochen Supper Claudia Gugenmus Bernward Klocke Alexander Hahn Max Schubach Mortiz Menzel Saskia Biskup Peter Freisinger Mario Deng Martin Braun Sven Perner Richard J H Smith Janeen L Andorf Jian Huang Kelli Ryckman Val C Sheffield Edwin M Stone Thomas Bair E Ann Black-Ziegelbein Terry A Braun Benjamin Darbro Adam P DeLuca Diana L Kolbe Todd E Scheetz Aiden E Shearer Rama Sompallae Kai Wang Alexander G Bassuk Erik Edens Katherine Mathews Steven A Moore Oleg A Shchelochkov Pamela Trapane Aaron Bossler Colleen A Campbell Jonathan W Heusel Anne Kwitek Tara Maga Karin Panzer Thomas Wassink Douglas Van Daele Hela Azaiez Kevin Booth Nic Meyer Michael M Segal Marc S Williams Gerard Tromp Peter White Donald Corsmeier Sara Fitzgerald-Butt Gail Herman Devon Lamb-Thrush Kim L McBride David Newsom Christopher R Pierson Alexander T Rakowsky Aleš Maver Luca Lovrečić Anja Palandačić Borut Peterlin Ali Torkamani Anna Wedell Mikael Huss Andrey Alexeyenko Jessica M Lindvall Måns Magnusson Daniel Nilsson Henrik Stranneheim Fulya Taylan Christian Gilissen Alexander Hoischen Bregje van Bon Helger Yntema Marcel Nelen Weidong Zhang Jason Sager Lu Zhang Kathryn Blair Deniz Kural Michael Cariaso Greg G Lennon Asif Javed Saloni Agrawal Pauline C Ng Komal S Sandhu Shuba Krishna Vamsi Veeramachaneni Ofer Isakov Eran Halperin Eitan Friedman Noam Shomron Gustavo Glusman Jared C Roach Juan Caballero Hannah C Cox Denise Mauldin Seth A Ament Lee Rowen Daniel R Richards F Anthony San Lucas Manuel L Gonzalez-Garay C Thomas Caskey Yu Bai Ying Huang Fang Fang Yan Zhang Zhengyuan Wang Jorge Barrera Juan M Garcia-Lobo Domingo González-Lamuño Javier Llorca Maria C Rodriguez Ignacio Varela Martin G Reese Francisco M De La Vega Edward Kiruluta Michele Cargill Reece K Hart Jon M Sorenson Gholson J Lyon David A Stevenson Bruce E Bray Barry M Moore Karen Eilbeck Mark Yandell Hongyu Zhao Lin Hou Xiaowei Chen Xiting Yan Mengjie Chen Cong Li Can Yang Murat Gunel Peining Li Yong Kong Austin C Alexander Zayed I Albertyn Kym M Boycott Dennis E Bulman Paul M K Gordon A Micheil Innes Bartha M Knoppers Jacek Majewski Christian R Marshall Jillian S Parboosingh Sarah L Sawyer Mark E Samuels Jeremy Schwartzentruber Isaac S Kohane David M Margulies

Genome Biol 2014 Mar 25;15(3):R53. Epub 2014 Mar 25.

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http://dx.doi.org/10.1186/gb-2014-15-3-r53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073084PMC
March 2014

Mutation of KCNJ8 in a patient with Cantú syndrome with unique vascular abnormalities - support for the role of K(ATP) channels in this condition.

Eur J Med Genet 2013 Dec 28;56(12):678-82. Epub 2013 Oct 28.

Division of Genetics and Genomics, The Manton Center for Orphan Disease Research, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejmg.2013.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902017PMC
December 2013

Functional genomic analysis of chromosomal aberrations in a compendium of 8000 cancer genomes.

Genome Res 2013 Feb 6;23(2):217-27. Epub 2012 Nov 6.

Center for Biomedical Informatics, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1101/gr.140301.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561863PMC
February 2013

Systematic identification of synergistic drug pairs targeting HIV.

Nat Biotechnol 2012 Nov 14;30(11):1125-30. Epub 2012 Oct 14.

Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, Division of Genetics, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nbt.2391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494743PMC
November 2012

Estimating enrichment of repetitive elements from high-throughput sequence data.

Genome Biol 2010 28;11(6):R69. Epub 2010 Jun 28.

Harvard-MIT Health Sciences and Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1186/gb-2010-11-6-r69DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911117PMC
November 2010

rSW-seq: algorithm for detection of copy number alterations in deep sequencing data.

BMC Bioinformatics 2010 Aug 18;11:432. Epub 2010 Aug 18.

Center for Biomedical Informatics, Harvard Medical School, 10 Shattuck St, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1186/1471-2105-11-432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939611PMC
August 2010