Publications by authors named "Louise Warnich"

61Publications

Pharmacogenetics of Antiretroviral Drug Response and Pharmacokinetic Variations in Indigenous South African Populations.

OMICS 2018 09;22(9):589-597

1 Systems Genetics Working Group, Department of Genetics, Stellenbosch University , Stellenbosch, South Africa .

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September 2018

Variation within voltage-gated calcium channel genes and antipsychotic treatment response in a South African first episode schizophrenia cohort.

Pharmacogenomics J 2019 02 22;19(1):109-114. Epub 2018 Jul 22.

Department of Genetics, Faculty of AgriSciences, Stellenbosch University, Stellenbosch, South Africa.

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February 2019

The genetic architecture of schizophrenia, bipolar disorder, obsessive-compulsive disorder and autism spectrum disorder.

Mol Cell Neurosci 2018 04 2;88:300-307. Epub 2018 Mar 2.

Department of Genetics, Stellenbosch University, Stellenbosch, South Africa.

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April 2018

Modification of the association between antipsychotic treatment response and childhood adversity by MMP9 gene variants in a first-episode schizophrenia cohort.

Psychiatry Res 2018 04 7;262:141-148. Epub 2018 Feb 7.

Systems Genetics Working Group, Department of Genetics, Faculty of AgriSciences, Stellenbosch University, Stellenbosch 7600, South Africa.

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April 2018

DNA methylation and antipsychotic treatment mechanisms in schizophrenia: Progress and future directions.

Prog Neuropsychopharmacol Biol Psychiatry 2018 Feb 7;81:38-49. Epub 2017 Oct 7.

Department of Genetics, Stellenbosch University, Stellenbosch 7600, South Africa. Electronic address:

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February 2018

Fine-mapping of antipsychotic response genome-wide association studies reveals novel regulatory mechanisms.

Pharmacogenomics 2017 Jan 19;18(2):105-120. Epub 2016 Dec 19.

Department of Genetics, Stellenbosch University, Stellenbosch, South Africa.

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January 2017

Toward a Global Roadmap for Precision Medicine in Psychiatry: Challenges and Opportunities.

OMICS 2016 10 16;20(10):557-564. Epub 2016 Sep 16.

1 Department of Psychiatry and Mental Health, University of Cape Town , Cape Town, South Africa .

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October 2016

The identification of novel genetic variants associated with antipsychotic treatment response outcomes in first-episode schizophrenia patients.

Pharmacogenet Genomics 2016 May;26(5):235-42

aDepartment of Genetics, Stellenbosch University, Stellenbosch Departments of bPsychiatry cMolecular Biology and Human Genetics, Stellenbosch University, Cape Town dDepartment of Statistics, University of the Western Cape, Bellville, South Africa eDepartment of Psychiatry, Zucker Hillside Hospital, North Shore-Long Island Jewish Health System, New York, New York, USA.

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May 2016

Biotechnology Innovators To Convene in Cape Town, South Africa: Pharmacogenetics and Precision Medicine Conference (April 7-9, 2016).

OMICS 2015 Dec 17;19(12):731-2. Epub 2015 Nov 17.

6 Institute for Cellular and Molecular Medicine, Department of Immunology, Faculty of Health Sciences, University of Pretoria , Pretoria, South Africa .

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December 2015

Evaluation of predictive CYP2C19 genotyping assays relative to measured phenotype in a South African cohort.

Pharmacogenomics 2015 5;16(12):1343-54. Epub 2015 Aug 5.

Department of Immunology, Faculty of Health Sciences, University of Pretoria, PO Box 2034, Pretoria 0001, South Africa.

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June 2016

H3Africa and the African life sciences ecosystem: building sustainable innovation.

OMICS 2014 Dec;18(12):733-9

1 Pharmacogenetics Research Group, Division of Human Genetics, Department of Clinical Laboratory Sciences and Institute for Infectious Disease and Molecular Medicine (IDM), Faculty of Health Sciences, University of Cape Town , South Africa .

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December 2014

Considerations for rare variants in drug metabolism genes and the clinical implications.

Expert Opin Drug Metab Toxicol 2014 Jun 28;10(6):873-84. Epub 2014 Mar 28.

Stellenbosch University, Genetics , Stellenbosch , South Africa

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June 2014

Next-generation sequencing of pharmacogenes: a critical analysis focusing on schizophrenia treatment.

Pharmacogenet Genomics 2013 Dec;23(12):666-74

aDepartment of Genetics, Stellenbosch University, Stellenbosch bDepartment of Psychiatry, Stikland Hospital, Stellenbosch University cSouth African National Bioinformatics Institute, University of the Western Cape, Cape Town, South Africa.

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December 2013

Cytochrome P450 pharmacogenetics in African populations.

Drug Metab Rev 2013 May 16;45(2):253-75. Epub 2013 Apr 16.

Department of Immunology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.

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May 2013

Public Health Pharmacogenomics and the Design Principles for Global Public Goods - Moving Genomics to Responsible Innovation.

Curr Pharmacogenomics Person Med 2013 Mar;11(1):1-4

Research Group on Complex Collaboration, Faculty of Management, McGill University ; Centre of Genomics and Policy, Department of Human Genetics, Faculty of Medicine, McGill University, Montreal, QC, Canada ; Data-Enabled Life Sciences Alliance International (DELSA Global), Seattle, WA, USA.

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March 2013

Iron homeostasis in porphyria cutanea tarda: mutation analysis of promoter regions of CP, CYBRD1, HAMP and SLC40A1.

J Clin Pathol 2013 Feb 25;66(2):160-1. Epub 2012 Sep 25.

Department of Genetics, University of Stellenbosch, Stellenbosch, South Africa.

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February 2013

Association of MB-COMT polymorphisms with schizophrenia-susceptibility and symptom severity in an African cohort.

Prog Neuropsychopharmacol Biol Psychiatry 2012 Oct 13;39(1):163-9. Epub 2012 Jun 13.

Department of Genetics, Stellenbosch University, Private Bag X1, Matieland 7602, South Africa.

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October 2012

Pharmacogenomic Research in South Africa: Lessons Learned and Future Opportunities in the Rainbow Nation.

Curr Pharmacogenomics Person Med 2011 Sep;9(3):191-207

Department of Genetics, Stellenbosch University, Stellenbosch, South Africa.

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September 2011

End of the Beginning and Public Health Pharmacogenomics: Knowledge in 'Mode 2' and P5 Medicine.

Curr Pharmacogenomics Person Med 2012 Jan;10(1):1-6

Centre of Genomics and Policy, Department of Human Genetics, Faculty of Medicine, McGill University, Montreal, QC, Canada.

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January 2012

Chromosome 22q11 in a Xhosa schizophrenia population.

S Afr Med J 2012 Feb 23;102(3 Pt 1):165-6. Epub 2012 Feb 23.

Department of Psychology, Stellenbosch University, South Africa.

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February 2012

Whole-genome resequencing in pharmacogenomics: moving away from past disparities to globally representative applications.

Pharmacogenomics 2011 Dec;12(12):1717-28

Department of Genetics, Stellenbosch University, Private Bag XI, Matieland 7602, South Africa.

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December 2011

Analysis of pharmacogenetic traits in two distinct South African populations.

Hum Genomics 2011 May;5(4):265-82

University of California, San Francisco, School of Pharmacy, Department of Clinical Pharmacy, CA 94143, USA.

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May 2011

Identification of a novel functional deletion variant in the 5'-UTR of the DJ-1 gene.

BMC Med Genet 2009 Oct 13;10:105. Epub 2009 Oct 13.

Division of Molecular Biology and Human Genetics, Faculty of Health Sciences, University of Stellenbosch, Cape Town, 8001, South Africa.

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October 2009

A pharmacogenetic study of CD4 recovery in response to HIV antiretroviral therapy in two South African population groups.

J Hum Genet 2009 May 13;54(5):261-5. Epub 2009 Mar 13.

Department of Genetics, Stellenbosch University, Private Bag X1, Matieland, South Africa.

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May 2009

Predictors of abnormal involuntary movement in an african schizophrenia population.

J Neuropsychiatry Clin Neurosci 2008 ;20(3):317-26

Department of Psychiatry, University of Stellenbosch, PO Box 19090, Tygerberg 7505, South Africa.

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April 2009

In silico promoters: modelling of cis-regulatory context facilitates target predictio.

J Cell Mol Med 2009 Feb 24;13(2):270-8. Epub 2008 May 24.

Department of Genetics, Stellenbosch University, Matieland, South Africa.

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February 2009

Association between the MnSOD Ala-9Val polymorphism and development of schizophrenia and abnormal involuntary movements in the Xhosa population.

Prog Neuropsychopharmacol Biol Psychiatry 2007 Apr 12;31(3):664-72. Epub 2007 Jan 12.

Department of Genetics, Stellenbosch University, Private Bag X1, Matieland, 7602, South Africa.

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April 2007

Analysis of viral and genetic factors in South African patients with multiple sclerosis.

Metab Brain Dis 2006 Sep 22;21(2-3):163-9. Epub 2006 Jul 22.

Genecare Molecular Genetics (Pty) Ltd, Christiaan Barnard Memorial Hospital, 162 Longmarket Street, Cape Town, South Africa.

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September 2006

Lack of clinical manifestation of hereditary haemochromatosis in South African patients with multiple sclerosis.

Metab Brain Dis 2006 Sep 19;21(2-3):109-20. Epub 2006 Jul 19.

Genecare Molecular Genetics Pty Ltd, Christiaan Barnard Memorial Hospital, 162 Longmarket Street, Cape Town, South Africa.

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September 2006

Gene symbol: SLC40A1. Disease: primary iron overload.

Hum Genet 2005 Dec;118(3-4):547

Department of Genetics, University of Stellenbosch, South Africa.

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December 2005

Association of functional polymorphisms of SLC11A1 with risk of esophageal cancer in the South African Colored population.

Cancer Genet Cytogenet 2005 May;159(1):48-52

Department of Genetics, University of Stellenbosch, Private Bag X1, Matieland 7602, South Africa.

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May 2005

Analysis of genes implicated in iron regulation in individuals presenting with primary iron overload.

Hum Genet 2004 Oct 24;115(5):409-17. Epub 2004 Aug 24.

MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, United Kingdom.

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October 2004

Expression of the SLC11A1 (NRAMP1) 5'-(GT)n repeat: opposite effect in the presence of -237C-->T.

Blood Cells Mol Dis 2004 Jul-Aug;33(1):45-50

Department of Genetics, University of Stellenbosch, Stellenbosch, South Africa.

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January 2005