Louise Scharf

Louise Scharf

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Louise Scharf

Louise Scharf

Publications by authors named "Louise Scharf"

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21Publications

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Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies.

Elife 2017 05 26;6. Epub 2017 May 26.

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.

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http://dx.doi.org/10.7554/eLife.27389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472438PMC
May 2017

A New Glycan-Dependent CD4-Binding Site Neutralizing Antibody Exerts Pressure on HIV-1 In Vivo.

PLoS Pathog 2015 Oct 30;11(10):e1005238. Epub 2015 Oct 30.

Laboratory of Molecular Immunology, The Rockefeller University, New York, New York, United States of America; Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1005238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627763PMC
October 2015

Broadly Neutralizing Antibody 8ANC195 Recognizes Closed and Open States of HIV-1 Env.

Cell 2015 Sep;162(6):1379-90

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.08.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587768PMC
September 2015

Antibody engineering for increased potency, breadth and half-life.

Curr Opin HIV AIDS 2015 May;10(3):151-9

aDivision of Biology and Biological Engineering, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125, USA bHoward Hughes Medical Institute, Chevy Chase, MD 20815-6789, USA.

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http://dx.doi.org/10.1097/COH.0000000000000148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465343PMC
May 2015

Expression of CD1c enhances human invariant NKT cell activation by α-GalCer.

Cancer Immun 2013 10;13. Epub 2013 May 10.

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721260PMC
May 2014

Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike.

Cell Rep 2014 May 24;7(3):785-95. Epub 2014 Apr 24.

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA; Howard Hughes Medical Institute, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247140028
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http://dx.doi.org/10.1016/j.celrep.2014.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109818PMC
May 2014

Structural insights on the role of antibodies in HIV-1 vaccine and therapy.

Cell 2014 Feb;156(4):633-48

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA; Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674140014
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http://dx.doi.org/10.1016/j.cell.2014.01.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041625PMC
February 2014

Crystal structure of Vδ1 T cell receptor in complex with CD1d-sulfatide shows MHC-like recognition of a self-lipid by human γδ T cells.

Immunity 2013 Dec 14;39(6):1032-42. Epub 2013 Nov 14.

Committee on Immunology, University of Chicago, Chicago, IL 60637, USA; Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL 60637, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2013.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875342PMC
December 2013

Antibodies in HIV-1 vaccine development and therapy.

Science 2013 Sep;341(6151):1199-204

Laboratory of Molecular Immunology, The Rockefeller University, New York, NY 10065, USA.

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http://dx.doi.org/10.1126/science.1241144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970325PMC
September 2013

Highly stereocontrolled total synthesis of β-D-mannosyl phosphomycoketide: a natural product from Mycobacterium tuberculosis.

J Org Chem 2013 Jun 11;78(12):5970-86. Epub 2013 Jun 11.

Department of Biochemistry and Molecular Biology, University of Chicago, 929 East 57th Street, Chicago, Illinois 60637, United States.

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http://dx.doi.org/10.1021/jo4006602DOI Listing
June 2013

Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues.

Proc Natl Acad Sci U S A 2013 Jun 10;110(26):10598-603. Epub 2013 Jun 10.

Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1073/pnas.1309215110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696754PMC
June 2013

Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody.

Proc Natl Acad Sci U S A 2013 Apr 22;110(15):6049-54. Epub 2013 Mar 22.

Division of Biology, California Institute of Technology, Pasadena, CA 91125, USA.

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http://dx.doi.org/10.1073/pnas.1303682110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625305PMC
April 2013

Recognition of lyso-phospholipids by human natural killer T lymphocytes.

PLoS Biol 2009 Oct 27;7(10):e1000228. Epub 2009 Oct 27.

Department of Medical Microbiology and Immunology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.

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http://dx.doi.org/10.1371/journal.pbio.1000228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760207PMC
October 2009