Publications by authors named "Louise A Stephen"

11Publications

Conditional deletion of E11/Podoplanin in bone protects against ovariectomy-induced increases in osteoclast formation and activity.

Authors:
Katherine A Staines Mark Hopkinson Scott Dillon Louise A Stephen Robert Fleming Antonia Sophocleous David J Buttle Andrew A Pitsillides Colin Farquharson

Biosci Rep 2020 01;40(1)

Roslin Institute and R(D)SVS, The University of Edinburgh, Easter Bush, Midlothian, U.K.

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January 2020

ARL3 Mutations Cause Joubert Syndrome by Disrupting Ciliary Protein Composition.

Authors:
Sumaya Alkanderi Elisa Molinari Ranad Shaheen Yasmin Elmaghloob Louise A Stephen Veronica Sammut Simon A Ramsbottom Shalabh Srivastava George Cairns Noel Edwards Sarah J Rice Nour Ewida Amal Alhashem Kathryn White Colin G Miles David H Steel Fowzan S Alkuraya Shehab Ismail John A Sayer

Am J Hum Genet 2018 10 27;103(4):612-620. Epub 2018 Sep 27.

Institute of Genetic Medicine, Newcastle University, International Centre for Life, Central Parkway, Newcastle upon Tyne NE1 3BZ, UK; Renal Services, Newcastle Hospitals NHS Foundation Trust, Newcastle upon Tyne NE7 7DN, UK. Electronic address:

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October 2018

The Ciliary Machinery Is Repurposed for T Cell Immune Synapse Trafficking of LCK.

Authors:
Louise A Stephen Yasmin ElMaghloob Michael J McIlwraith Tamas Yelland Patricia Castro Sanchez Pedro Roda-Navarro Shehab Ismail

Dev Cell 2018 10 13;47(1):122-132.e4. Epub 2018 Sep 13.

CR-UK Beatson Institute, Garscube Estate, Switchback Road, Glasgow G61 1BD, UK; Institute of Cancer Sciences, University of Glasgow, Glasgow G12 8QQ, UK. Electronic address:

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October 2018

Non-muscle myosin IIB (Myh10) is required for epicardial function and coronary vessel formation during mammalian development.

Authors:
Liam A Ridge Karen Mitchell Ali Al-Anbaki Wasay Mohiuddin Shaikh Qureshi Louise A Stephen Gennadiy Tenin Yinhui Lu Irina-Elena Lupu Christopher Clowes Abigail Robertson Emma Barnes Jayne A Wright Bernard Keavney Elisabeth Ehler Simon C Lovell Karl E Kadler Kathryn E Hentges

PLoS Genet 2017 Oct 30;13(10):e1007068. Epub 2017 Oct 30.

Division of Evolution and Genome Sciences, School of Biological Sciences, Faculty of Biology, Medicine, and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, United Kingdom.

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October 2017

Maintaining protein composition in cilia.

Authors:
Louise A Stephen Yasmin Elmaghloob Shehab Ismail

Biol Chem 2017 12;399(1):1-11

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December 2017

Shuttling and sorting lipid-modified cargo into the cilia.

Authors:
Louise A Stephen Shehab Ismail

Biochem Soc Trans 2016 10;44(5):1273-1280

CR-UK Beatson Institute, Garscube Estate Switchback Road, Glasgow G61 1BD, U.K.

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October 2016

TALPID3 controls centrosome and cell polarity and the human ortholog KIAA0586 is mutated in Joubert syndrome (JBTS23).

Authors:
Louise A Stephen Hasan Tawamie Gemma M Davis Lars Tebbe Peter Nürnberg Gudrun Nürnberg Holger Thiele Michaela Thoenes Eugen Boltshauser Steffen Uebe Oliver Rompel André Reis Arif B Ekici Lynn McTeir Amy M Fraser Emma A Hall Pleasantine Mill Nicolas Daudet Courtney Cross Uwe Wolfrum Rami Abou Jamra Megan G Davey Hanno J Bolz

Elife 2015 Sep 19;4. Epub 2015 Sep 19.

Institute of Human Genetics, University Hospital of Cologne, Cologne, Germany.

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September 2015

Loss of cilia causes embryonic lung hypoplasia, liver fibrosis, and cholestasis in the talpid3 ciliopathy mutant.

Authors:
Megan G Davey Lynn McTeir Andrew M Barrie Lucy J Freem Louise A Stephen

Organogenesis 2014 Apr-Jun;10(2):177-85. Epub 2014 Apr 17.

Division of Developmental Biology; The Roslin Institute and R(D)SVS; University of Edinburgh; Midlothian, UK.

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February 2016

The chicken left right organizer has nonmotile cilia which are lost in a stage-dependent manner in the talpid(3) ciliopathy.

Authors:
Louise A Stephen Edward J Johnson Gemma M Davis Lynn McTeir Jamie Pinkham Neema Jaberi Megan G Davey

Genesis 2014 Jun 15;52(6):600-13. Epub 2014 Apr 15.

Division of Developmental Biology, The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, United Kingdom.

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June 2014

Failure of centrosome migration causes a loss of motile cilia in talpid(3) mutants.

Authors:
Louise A Stephen Gemma M Davis Katie E McTeir John James Lynn McTeir Martin Kierans Andrew Bain Megan G Davey

Dev Dyn 2013 Aug 11;242(8):923-31. Epub 2013 Jun 11.

Division of Developmental Biology, The Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, UK.

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August 2013

Structural and functional investigations of Matrilin-1 A-domains reveal insights into their role in cartilage ECM assembly.

Authors:
Maryline Fresquet Thomas A Jowitt Louise A Stephen Joni Ylöstalo Michael D Briggs

J Biol Chem 2010 Oct 21;285(44):34048-61. Epub 2010 Aug 21.

Faculty of Life Sciences, Wellcome Trust Centre for Cell-Matrix Research, University of Manchester, Manchester M13 9PT, United Kingdom.

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October 2010