Publications by authors named "Louis J Ignarro"

100Publications

May Mangafodipir or Other SOD Mimetics Contribute to Better Care in COVID-19 Patients?

Antioxidants (Basel) 2020 Oct 10;9(10). Epub 2020 Oct 10.

Department of Pharmacology, UCLA School of Medicine, 264 El Camino Drive, Beverly Hills, CA 90212, USA.

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http://dx.doi.org/10.3390/antiox9100971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7601469PMC
October 2020

Inhaled NO and COVID-19.

Authors:
Louis J Ignarro

Br J Pharmacol 2020 08 10;177(16):3848-3849. Epub 2020 May 10.

Department of Pharmacology, UCLA School of Medicine, Beverly Hills, California, USA.

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http://dx.doi.org/10.1111/bph.15085DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7393191PMC
August 2020

Nitric oxide is not just blowing in the wind.

Authors:
Louis J Ignarro

Br J Pharmacol 2019 01;176(2):131-134

UCLA School of Medicine, Beverly Hills, CA, USA.

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http://dx.doi.org/10.1111/bph.14540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295410PMC
January 2019

Calmangafodipir [Ca4Mn(DPDP)5], mangafodipir (MnDPDP) and MnPLED with special reference to their SOD mimetic and therapeutic properties.

Drug Discov Today 2015 Apr 20;20(4):411-21. Epub 2014 Nov 20.

Department of Diagnostic Radiology, Lund University, Malmö, Sweden.

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http://dx.doi.org/10.1016/j.drudis.2014.11.008DOI Listing
April 2015

Erectile hydraulics: maximizing inflow while minimizing outflow.

J Sex Med 2014 May 13;11(5):1208-20. Epub 2014 Feb 13.

Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1111/jsm.12457DOI Listing
May 2014

Effects of nitric oxide on cell proliferation: novel insights.

J Am Coll Cardiol 2013 Jul 9;62(2):89-95. Epub 2013 May 9.

Department of Pharmacology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California.

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http://dx.doi.org/10.1016/j.jacc.2013.03.070DOI Listing
July 2013

Neuroprotective effects of valproic acid against hemin toxicity: possible involvement of the down-regulation of heme oxygenase-1 by regulating ubiquitin-proteasomal pathway.

Neurochem Int 2013 Feb 5;62(3):240-50. Epub 2013 Jan 5.

Department of Neurology, Center for Neuroscience Research, SMART Institute of Advanced Biomedical Science, School of Medicine, Konkuk University, 1 Hwayang-dong, Gwangjin-gu, Seoul 143-701, Republic of Korea.

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http://dx.doi.org/10.1016/j.neuint.2012.12.019DOI Listing
February 2013

Glycoxydation promotes vascular damage via MAPK-ERK/JNK pathways.

J Cell Physiol 2012 Nov;227(11):3639-47

Department of General Pathology, U.O.C. Immunohematology, and Excellence Research Centre on Cardiovascular Disease, 1st School of Medicine, Second University of Naples, Naples, Italy.

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http://dx.doi.org/10.1002/jcp.24070DOI Listing
November 2012

Adipose tissue-derived stem cell-seeded small intestinal submucosa for tunica albuginea grafting and reconstruction.

Proc Natl Acad Sci U S A 2012 Feb 23;109(6):2090-5. Epub 2012 Jan 23.

Department of Urology, Tulane University Health Sciences Center, New Orleans, LA 70112, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1113810109
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http://dx.doi.org/10.1073/pnas.1113810109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277542PMC
February 2012

The link between erectile and cardiovascular health: the canary in the coal mine.

Am J Cardiol 2011 Aug 31;108(4):599-606. Epub 2011 May 31.

Department of Obstetrics and Gynecology, David Geffen School of Medicine, University of California, Los Angeles, California, USA.

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http://dx.doi.org/10.1016/j.amjcard.2011.03.093DOI Listing
August 2011

Regulation of tissue plasminogen activator/plasminogen activator inhibitor-1 by hydrocortisone in rat primary astrocytes.

J Neurosci Res 2011 Jul 15;89(7):1059-69. Epub 2011 Mar 15.

Department of Neurology and Institute of Biomedical Science and Technology, Konkuk University, Seoul, Korea.

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http://dx.doi.org/10.1002/jnr.22619DOI Listing
July 2011

Dose-dependent modulatory effects of insulin on glucose-induced endothelial senescence in vitro and in vivo: a relationship between telomeres and nitric oxide.

J Pharmacol Exp Ther 2011 Jun 28;337(3):591-9. Epub 2011 Feb 28.

Department of Geriatrics, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.

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http://dx.doi.org/10.1124/jpet.110.177584DOI Listing
June 2011

Directed in vivo angiogenesis assay and the study of systemic neoangiogenesis in cancer.

Int J Cancer 2011 Apr 6;128(7):1505-8. Epub 2011 Jan 6.

Department of General Pathology, 1st School of Medicine, II University of Naples, Naples, Italy.

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http://dx.doi.org/10.1002/ijc.25743DOI Listing
April 2011

Biphasic regulation of tissue plasminogen activator activity in ischemic rat brain and in cultured neural cells: essential role of astrocyte-derived plasminogen activator inhibitor-1.

Neurochem Int 2011 Feb 28;58(3):423-33. Epub 2010 Dec 28.

Department of Pharmacology, Research Institute of Medical Sciences and Institute of Functional Genomics, Konkuk University, Seoul, Republic of Korea.

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http://dx.doi.org/10.1016/j.neuint.2010.12.020DOI Listing
February 2011

Endothelial progenitor cells as therapeutic agents in the microcirculation: an update.

Atherosclerosis 2011 Mar 3;215(1):9-22. Epub 2010 Nov 3.

Department of General Pathology, Division of Clinical Pathology and Excellence Research Center on Cardiovascular Diseases, 1st School of Medicine, II University of Naples, 80138 Naples, Italy.

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http://dx.doi.org/10.1016/j.atherosclerosis.2010.10.039DOI Listing
March 2011

Melatonin synergistically increases resveratrol-induced heme oxygenase-1 expression through the inhibition of ubiquitin-dependent proteasome pathway: a possible role in neuroprotection.

J Pineal Res 2011 Mar 15;50(2):110-23. Epub 2010 Nov 15.

Departments of Neurology Pharmacology Rehabilitation, Center for Geriatric Neuroscience Research, Institute of Biomedical Science and Technology, School of Medicine, Konkuk University, Seoul, Korea.

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http://dx.doi.org/10.1111/j.1600-079X.2010.00820.xDOI Listing
March 2011

A multifaceted approach to maximize erectile function and vascular health.

Fertil Steril 2010 Dec 1;94(7):2514-20. Epub 2010 Jun 1.

Reproductive Partners Medical Group, Redondo Beach, California 90277, USA.

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http://dx.doi.org/10.1016/j.fertnstert.2010.04.026DOI Listing
December 2010

Nitric oxide and pathogenic mechanisms involved in the development of vascular diseases.

Arch Pharm Res 2009 Aug 29;32(8):1103-8. Epub 2009 Aug 29.

Department of General Pathology and Excellence Research Center on Cardiovascular Diseases, University of Naples, Italy.

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http://dx.doi.org/10.1007/s12272-009-1801-1DOI Listing
August 2009

Preface to this special journal issue on nitric oxide chemistry and biology.

Authors:
Louis J Ignarro

Arch Pharm Res 2009 Aug;32(8):1099-101

Department of Medical and Molecular Pharmacology, University of California Los Angeles, Center for Health Sciences, 90095-1735, USA.

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http://dx.doi.org/10.1007/s12272-009-1800-2DOI Listing
August 2009

Mechanisms by which exercise training benefits patients with heart failure.

Nat Rev Cardiol 2009 Apr;6(4):292-300

Department of Anesthesia and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://www.nature.com/articles/nrcardio.2009.8
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http://dx.doi.org/10.1038/nrcardio.2009.8DOI Listing
April 2009

Hydrogen sulfide as a mediator of human corpus cavernosum smooth-muscle relaxation.

Proc Natl Acad Sci U S A 2009 Mar 2;106(11):4513-8. Epub 2009 Mar 2.

Department of Experimental Pharmacology, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.

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http://dx.doi.org/10.1073/pnas.0807974105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657379PMC
March 2009

Different pharmacological properties of two enantiomers in a unique beta-blocker, nebivolol.

Authors:
Louis J Ignarro

Cardiovasc Ther 2008 ;26(2):115-34

Department of Medical and Molecular Pharmacology, University of California Los Angeles School of Medicine, Center for Health Sciences, Los Angeles, California 90095-1735, USA.

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http://dx.doi.org/10.1111/j.1527-3466.2008.00044.xDOI Listing
September 2008

Therapeutic dose of nebivolol, a nitric oxide-releasing beta-blocker, reduces atherosclerosis in cholesterol-fed rabbits.

Nitric Oxide 2008 Aug 4;19(1):57-63. Epub 2008 Apr 4.

Department of General Pathology, Excellence Research Center on Cardiovascular Diseases, Complesso S. Andrea della Dame, Via de Crecchio 7, 1st School of Medicine, II University of Naples, 80138 Naples, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S108986030800042
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http://dx.doi.org/10.1016/j.niox.2008.03.004DOI Listing
August 2008

IL-4 and IL-13 upregulate ornithine decarboxylase expression by PI3K and MAP kinase pathways in vascular smooth muscle cells.

Am J Physiol Cell Physiol 2008 May 26;294(5):C1198-205. Epub 2008 Mar 26.

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095-1735, USA.

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http://dx.doi.org/10.1152/ajpcell.00325.2007DOI Listing
May 2008

Deletion of Yin Yang 1 protein in osteosarcoma cells on cell invasion and CXCR4/angiogenesis and metastasis.

Cancer Res 2008 Mar;68(6):1797-808

Department of General Pathology, Division of Clinical Pathology, 1st School of Medicine, II University of Naples, Naples, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-5582DOI Listing
March 2008

NCX-4040, a nitric oxide-releasing aspirin, sensitizes drug-resistant human ovarian xenograft tumors to cisplatin by depletion of cellular thiols.

J Transl Med 2008 Feb 26;6. Epub 2008 Feb 26.

Center for Biomedical EPR Spectroscopy and Imaging, Davis Heart and Lung Research Institute, Department of Internal Medicine, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1186/1479-5876-6-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2267444PMC
February 2008

NCX-4016, a nitro-derivative of aspirin, inhibits EGFR and STAT3 signaling and modulates Bcl-2 proteins in cisplatin-resistant human ovarian cancer cells and xenografts.

Cell Cycle 2008 Jan 28;7(1):81-8. Epub 2007 Sep 28.

Davis Heart and Lung Research Institute and Comprehensive Cancer Center, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2890223PMC
http://dx.doi.org/10.4161/cc.7.1.5103DOI Listing
January 2008

Therapeutic effects of autologous bone marrow cells and metabolic intervention in the ischemic hindlimb of spontaneously hypertensive rats involve reduced cell senescence and CXCR4/Akt/eNOS pathways.

J Cardiovasc Pharmacol 2007 Oct;50(4):424-33

Department of General Pathology, Division of Clinical Pathology and Excellence Research Center on Cardiovascular Diseases, 1st School of Medicine, II University of Naples, Naples, Italy.

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http://dx.doi.org/10.1097/FJC.0b013e31812564e4DOI Listing
October 2007

Therapeutic approaches in vascular repair induced by adult bone marrow cells and circulating progenitor endothelial cells.

Curr Pharm Des 2007 ;13(31):3245-51

Department of General Pathology, Division of Clinical Pathology and Excellence Research Center on Cardiovascular Diseases, 1st School of Medicine, II University of Naples, Italy.

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http://dx.doi.org/10.2174/138161207782341303DOI Listing
December 2007

Heart mtNOS, a key mediator of oxidative injury in ischemia/reperfusion.

Authors:
Louis J Ignarro

J Mol Cell Cardiol 2007 Oct 24;43(4):409-10. Epub 2007 Jul 24.

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http://linkinghub.elsevier.com/retrieve/pii/S002228280701161
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http://dx.doi.org/10.1016/j.yjmcc.2007.07.053DOI Listing
October 2007

Nitroaspirin (NCX-4016), an NO donor, is antiangiogenic through induction of loss of redox-dependent viability and cytoskeletal reorganization in endothelial cells.

Antioxid Redox Signal 2007 Nov;9(11):1837-49

Department of Internal Medicine, Divisions of Cardiology and Pulmonary, Critical Care, and Sleep Medicine, Dorothy M. Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1089/ars.2007.1603DOI Listing
November 2007

Bone marrow cell-mediated cardiovascular repair: potential of combined therapies.

Trends Mol Med 2007 Jul 15;13(7):278-86. Epub 2007 Jun 15.

Department of General Pathology, Division of Clinical Pathology and Excellence Research Center on Cardiovascular Diseases, 1st School of Medicine, II University of Naples, Italy.

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http://dx.doi.org/10.1016/j.molmed.2007.05.004DOI Listing
July 2007

The influence of pomegranate fruit extract in comparison to regular pomegranate juice and seed oil on nitric oxide and arterial function in obese Zucker rats.

Nitric Oxide 2007 Aug 5;17(1):50-4. Epub 2007 May 5.

Department of General Pathology and Excellence Research Center on Cardiovascular Diseases, Complesso S. Andrea delle Dame, Via de Crecchio 7, 1st School of Medicine, II University of Naples, Naples 80138, Italy.

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http://www.wonderfulpomegranateresearch.com/media/pdf/health
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http://linkinghub.elsevier.com/retrieve/pii/S108986030700043
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http://dx.doi.org/10.1016/j.niox.2007.04.005DOI Listing
August 2007

The L-arginine paradox: Importance of the L-arginine/asymmetrical dimethylarginine ratio.

Pharmacol Ther 2007 Jun 1;114(3):295-306. Epub 2007 Apr 1.

Institute of Clinical Pharmacology, University Hospital, Otto-von-Guericke University, Leipziger Strasse 44, 39120 Magdeburg, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S016372580700050
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http://dx.doi.org/10.1016/j.pharmthera.2007.03.002DOI Listing
June 2007

High glucose downregulates the number of caveolae in monocytes through oxidative stress from NADPH oxidase: implications for atherosclerosis.

Biochim Biophys Acta 2007 Mar 8;1772(3):364-72. Epub 2006 Dec 8.

Department of Geriatrics, Nagoya University Graduate School of Medicine, 466-8550 Nagoya, Japan.

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http://dx.doi.org/10.1016/j.bbadis.2006.11.011DOI Listing
March 2007

Low-dose L-arginine administration increases microperfusion of hindlimb muscle without affecting blood pressure in rats.

Proc Natl Acad Sci U S A 2007 Jan 17;104(4):1407-11. Epub 2007 Jan 17.

Laboratory of Amino Acid Application, AminoScience Laboratories, Ajinomoto Co., Inc., 1-1 Suzuki-cho Kawasaki-ku, Kawasaki 210-8681, Japan.

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http://dx.doi.org/10.1073/pnas.0610207104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1783113PMC
January 2007

Autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the diabetic mouse hindlimb.

Cell Cycle 2006 Dec 15;5(24):2903-8. Epub 2006 Dec 15.

Department of General Pathology, Division of Clinical Pathology and Excellence Research Center on Cardiovascular Diseases, 1st School of Medicine, II University of Naples, Naples, Italy.

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http://dx.doi.org/10.4161/cc.5.24.3568DOI Listing
December 2006

Nutrition and cardiovascular disease: putting a pathogenic framework into focus.

Cardiovasc Res 2007 Jan 29;73(2):253-6. Epub 2006 Nov 29.

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http://dx.doi.org/10.1016/j.cardiores.2006.11.032DOI Listing
January 2007

Endothelial cellular senescence is inhibited by nitric oxide: implications in atherosclerosis associated with menopause and diabetes.

Proc Natl Acad Sci U S A 2006 Nov 30;103(45):17018-23. Epub 2006 Oct 30.

Department of Geriatrics, Nagoya University Graduate School of Medicine, Tsuruma-cho 65, Showa-ku, Nagoya 466-8550, Japan.

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http://dx.doi.org/10.1073/pnas.0607873103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1629003PMC
November 2006

Role of oxidative stress in experimental sepsis and multisystem organ dysfunction.

Free Radic Res 2006 Jul;40(7):665-72

Department of Anesthesiology and Critical Care Medicine, University of Eastern Piedmont, Novara, Italy.

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http://dx.doi.org/10.1080/10715760600669612DOI Listing
July 2006

Nutrition, physical activity, and cardiovascular disease: an update.

Cardiovasc Res 2007 Jan 21;73(2):326-40. Epub 2006 Jul 21.

Department of Molecular Pharmacology, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.cardiores.2006.06.030DOI Listing
January 2007

Nitric oxide (NO) is a new clinical biomarker of survival in the elderly patients and its efficacy might be nearly equal to albumin.

Nitric Oxide 2007 Feb 21;16(1):157-63. Epub 2006 Jun 21.

Department of Geriatrics, Nagoya University Graduate School of Medicine, 65 Tsuruma-cho, Showa-ku, Nagoya City 466-8550, Japan.

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http://dx.doi.org/10.1016/j.niox.2006.06.002DOI Listing
February 2007

Clonogenic multipotent stem cells in human adipose tissue differentiate into functional smooth muscle cells.

Proc Natl Acad Sci U S A 2006 Aug 31;103(32):12167-72. Epub 2006 Jul 31.

Department of Urology, University of California School of Medicine, Los Angeles, CA 90024, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0604850103
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http://dx.doi.org/10.1073/pnas.0604850103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1567713PMC
August 2006

Therapeutic effects of concurrent autologous bone marrow cell infusion and metabolic intervention in ischemia-induced angiogenesis in the hypercholesterolemic mouse hindlimb.

Int J Cardiol 2007 Apr 27;117(2):238-43. Epub 2006 Jul 27.

Department of General Pathology, Division of Clinical Pathology and Excellence Research Center on Cardiovascular Diseases, 1st School of Medicine, II University of Naples, Naples 80138, Italy.

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http://dx.doi.org/10.1016/j.ijcard.2006.05.020DOI Listing
April 2007

Polymorphisms in endothelial nitric oxide synthase and carotid artery atherosclerosis.

J Clin Pathol 2007 Apr 12;60(4):341-4. Epub 2006 Jul 12.

Department of General Pathology, Division of Clinical Pathology, 1st School of Medicine, II University of Naples, Naples, Italy.

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http://dx.doi.org/10.1136/jcp.2006.040550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2001110PMC
April 2007

D-4F decreases brain arteriole inflammation and improves cognitive performance in LDL receptor-null mice on a Western diet.

J Lipid Res 2006 Oct 11;47(10):2148-60. Epub 2006 Jul 11.

Department of Medicine, David Geffen School of Medicine at the University of California-Los Angeles, Los Angeles, CA 90095-1679, USA.

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http://www.jlr.org/lookup/doi/10.1194/jlr.M600214-JLR200
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http://dx.doi.org/10.1194/jlr.M600214-JLR200DOI Listing
October 2006

Nitric oxide and atherosclerosis: an update.

Nitric Oxide 2006 Dec 15;15(4):265-79. Epub 2006 Apr 15.

Department of General Pathology and Excellence Research Center on Cardiovascular Diseases, First School of Medicine, II University of Naples, Naples 80134, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S108986030600054
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http://dx.doi.org/10.1016/j.niox.2006.03.011DOI Listing
December 2006

Free radical biology and medicine: it's a gas, man!

Am J Physiol Regul Integr Comp Physiol 2006 Sep 20;291(3):R491-511. Epub 2006 Apr 20.

Biodynamics Institute, Louisiana State University, Baton Rouge, LA 70803, USA.

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http://dx.doi.org/10.1152/ajpregu.00614.2005DOI Listing
September 2006

Pomegranate juice protects nitric oxide against oxidative destruction and enhances the biological actions of nitric oxide.

Nitric Oxide 2006 Sep 19;15(2):93-102. Epub 2006 Apr 19.

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/j.niox.2006.03.001DOI Listing
September 2006

Reversal to cisplatin sensitivity in recurrent human ovarian cancer cells by NCX-4016, a nitro derivative of aspirin.

Proc Natl Acad Sci U S A 2006 Mar 23;103(10):3914-9. Epub 2006 Feb 23.

Center for Biomedical Electron Paramagnetic Resonance Spectroscopy and Imaging, The Dorothy M. Davis Heart and Lung Research Institute, Department of Internal Medicine, Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1073/pnas.0511250103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1450164PMC
March 2006

The role of oxidative stress in adult critical care.

Free Radic Biol Med 2006 Feb 18;40(3):398-406. Epub 2005 Nov 18.

Department of Anesthesiology and Critical Care Medicine, University of Eastern Piedmont, 28100 Novara, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S089158490500666
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http://dx.doi.org/10.1016/j.freeradbiomed.2005.10.054DOI Listing
February 2006

Pomegranate juice reduces oxidized low-density lipoprotein downregulation of endothelial nitric oxide synthase in human coronary endothelial cells.

Nitric Oxide 2006 Nov 18;15(3):259-63. Epub 2006 Jan 18.

Department of General Pathology and Excellence Research Center on Cardiovascular Disease, University of Naples, Italy.

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http://dx.doi.org/10.1016/j.niox.2005.12.004DOI Listing
November 2006

Beneficial effects of concurrent autologous bone marrow cell therapy and metabolic intervention in ischemia-induced angiogenesis in the mouse hindlimb.

Proc Natl Acad Sci U S A 2005 Nov 14;102(47):17202-6. Epub 2005 Nov 14.

Department of General Pathology, Division of Clinical Pathology and Excellence Research Center on Cardiovascular Diseases, School of Medicine, Second University of Naples, Naples 80138, Italy.

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http://dx.doi.org/10.1073/pnas.0508534102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1288005PMC
November 2005

l-Citrulline and l-arginine supplementation retards the progression of high-cholesterol-diet-induced atherosclerosis in rabbits.

Proc Natl Acad Sci U S A 2005 Sep 12;102(38):13681-6. Epub 2005 Sep 12.

Department of Geriatrics, Nagoya University Graduate School of Medicine, 65 Tsuruma-cho, Showa-ku, Nagoya 466-8550, Japan.

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http://dx.doi.org/10.1073/pnas.0506595102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1224660PMC
September 2005

Nitric oxide.

Authors:
Louis J Ignarro

Curr Top Med Chem 2005 ;5(7):595

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http://dx.doi.org/10.2174/1568026054679371DOI Listing
November 2005

Rapid nitric oxide-mediated S-nitrosylation of estrogen receptor: regulation of estrogen-dependent gene transcription.

Proc Natl Acad Sci U S A 2005 Feb 7;102(7):2632-6. Epub 2005 Feb 7.

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1073/pnas.0409854102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC548976PMC
February 2005

Sp1 transcription factor expression is regulated by estrogen-related receptor alpha1.

Biochem Biophys Res Commun 2005 Mar;328(1):165-72

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA, CHS, 23-305, Los Angeles, CA 90095-1735, USA.

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http://dx.doi.org/10.1016/j.bbrc.2004.12.165DOI Listing
March 2005

Novel features of nitric oxide, endothelial nitric oxide synthase, and atherosclerosis.

Curr Diab Rep 2005 Feb;5(1):17-23

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, 23-305 Center for Health Sciences, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1007/s11892-005-0062-8DOI Listing
February 2005

Endothelial nitric oxide synthase activation is critical for vascular leakage during acute inflammation in vivo.

Proc Natl Acad Sci U S A 2005 Jan 7;102(3):904-8. Epub 2005 Jan 7.

Dipartimento di Farmacologia Sperimentale, Via Domenico Montesano 49, Università di Napoli-Federico II, 80131 Naples, Italy.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0408906102
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http://dx.doi.org/10.1073/pnas.0408906102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC545512PMC
January 2005

Experimental evidences of nitric oxide-dependent vasodilatory activity of nebivolol, a third-generation beta-blocker.

Authors:
Louis J Ignarro

Blood Press Suppl 2004 Oct;1:2-16

Department of Medical and Molecular Pharmacology, UCLA School of Medicine, 23-120 Center for Health Sciences, Box 951735, Los Angeles, CA 90095-1735, USA.

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October 2004

Combined effect of testosterone and apocynin on nitric oxide and superoxide production in PMA-differentiated THP-1 cells.

Biochim Biophys Acta 2004 Sep;1693(3):185-91

Department of Geriatrics, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, 466 8550, Nagoya, Japan.

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http://dx.doi.org/10.1016/j.bbamcr.2004.08.002DOI Listing
September 2004

Regulation of inducible nitric oxide synthase expression in advanced glycation end product-stimulated raw 264.7 cells: the role of heme oxygenase-1 and endogenous nitric oxide.

Diabetes 2004 Jul;53(7):1841-50

David Geffen School of Medicine at UCLA, Department of Molecular and Medical Pharmacology, Center for Health Sciences, 23-305, Los Angeles, CA 90095-1735.

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http://dx.doi.org/10.2337/diabetes.53.7.1841DOI Listing
July 2004

Novel features of nitric oxide, endothelial nitric oxide synthase, and atherosclerosis.

Curr Atheroscler Rep 2004 Jul;6(4):281-7

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, 12-138 Center for Health Sciences, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1007/s11883-004-0059-9DOI Listing
July 2004

Estrogen receptor-mediated vascular responsiveness to nebivolol: a novel endothelium-related mechanism of therapeutic vasorelaxation.

J Cardiovasc Pharmacol 2004 May;43(5):638-44

Department of Molecular and Medical Pharmacology, University of California, Los Angeles, 90095-1735, USA.

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http://dx.doi.org/10.1097/00005344-200405000-00005DOI Listing
May 2004

Nitric oxide: inhibitory effects on endothelial cell calcium signaling, prostaglandin I2 production and nitric oxide synthase expression.

Cardiovasc Res 2004 Apr;62(1):194-201

Department of Internal Medicine III, Hamamatsu University School of Medicine, Handayama, Hamamatsu 431-3192, Japan.

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http://dx.doi.org/10.1016/j.cardiores.2003.12.028DOI Listing
April 2004

Gene transfer of endothelial NO synthase, but not eNOS plus inducible NOS, regressed atherosclerosis in rabbits.

Cardiovasc Res 2004 Feb;61(2):339-51

Department of Geriatrics, Nagoya University Graduate School of Medicine, 65 Tsuruma-cho, Showa, Nagoya 466-8550, Japan.

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http://dx.doi.org/10.1016/j.cardiores.2003.09.027DOI Listing
February 2004

A new role for cardioplegic buffering: should acidosis or calcium accumulation be counteracted to salvage jeopardized hearts?

J Thorac Cardiovasc Surg 2003 Nov;126(5):1442-8

Department of Surgery, Division of Cardiothoracic Surgery, University of California, Los Angeles, School of Medicine, USA.

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http://dx.doi.org/10.1016/s0022-5223(03)00599-3DOI Listing
November 2003

Estrogen-related receptor alpha 1 up-regulates endothelial nitric oxide synthase expression.

Proc Natl Acad Sci U S A 2003 Nov 10;100(24):14451-6. Epub 2003 Nov 10.

Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, 23-305 CHS, Los Angeles, CA 90095-1735, USA.

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http://dx.doi.org/10.1073/pnas.2235590100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC283612PMC
November 2003

Concomitant production of nitric oxide and superoxide in human macrophages.

Biochem Biophys Res Commun 2003 Oct;310(2):367-70

Department of Geriatrics, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, 466 8550 Nagoya, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2003.08.133DOI Listing
October 2003

Oxidation-sensitive mechanisms, vascular apoptosis and atherosclerosis.

Trends Mol Med 2003 Aug;9(8):351-9

Department of Pharmacological Sciences, University of Salerno, 84084 Salerno, Italy.

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http://dx.doi.org/10.1016/s1471-4914(03)00139-4DOI Listing
August 2003

Cell density-enhanced expression of inducible nitric oxide synthase in murine macrophages mediated by interferon-beta.

Nitric Oxide 2003 Jun;8(4):222-30

Department of Molecular and Medical Pharmacology, UCLA, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1016/s1089-8603(03)00027-2DOI Listing
June 2003

17beta-estradiol inhibits NADPH oxidase activity through the regulation of p47phox mRNA and protein expression in THP-1 cells.

Biochim Biophys Acta 2003 May;1640(2-3):113-8

Department of Geriatrics, Nagoya University Graduate School of Medicine, 65, Tsuruma-cho, Showa-ku, Nagoya 466-8550, Japan.

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http://dx.doi.org/10.1016/s0167-4889(03)00026-0DOI Listing
May 2003

Deep hypothermic circulatory arrest and global reperfusion injury: avoidance by making a pump prime reperfusate--a new concept.

J Thorac Cardiovasc Surg 2003 Mar;125(3):625-32

Division of Cardiovascular Surgery, University of California at Los Angeles Medical Center, USA.

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http://dx.doi.org/10.1067/mtc.2003.96DOI Listing
March 2003

Endothelial dysfunction after arterial thrombosis is ameliorated by L-arginine in combination with thrombolysis.

J Vasc Interv Radiol 2003 Feb;14(2 Pt 1):233-9

Department of Vascular Surgery, Wilford Hall Medical Center, 2200 Bergquist Drive, Suite 1, Lackland Air Force Base, Texas 78236, USA.

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http://dx.doi.org/10.1097/01.rvi.0000058326.82956.b8DOI Listing
February 2003

Wei Lun Visiting Professorial Lecture: Nitric oxide in the regulation of vascular function: an historical overview.

Authors:
Louis J Ignarro

J Card Surg 2002 Jul-Aug;17(4):301-6

Department of Molecular and Medical Pharmacology, UCLA School of Medicine, Center for the Health sciences, Los Angeles, California 90095-1735, USA.

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http://dx.doi.org/10.1111/j.1540-8191.2001.tb01148.xDOI Listing
May 2003

Nitric oxide-releasing drugs.

Annu Rev Pharmacol Toxicol 2003 10;43:97-123. Epub 2002 Jan 10.

Department of Medicine-0682, University of California, San Diego, La Jolla, California 92093, USA.

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http://dx.doi.org/10.1146/annurev.pharmtox.43.100901.140226DOI Listing
September 2003

Inhibitors of nitric oxide promote microvascular thrombosis.

Arch Facial Plast Surg 2003 Jan-Feb;5(1):31-5

Division of Head and Neck Surgery, UCLA School of Medicine, Los Angeles, CA 90095, USA.

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http://dx.doi.org/10.1001/archfaci.5.1.31DOI Listing
June 2003

Nuclear factor-kappa B and mitogen-activated protein kinases mediate nitric oxide-enhanced transcriptional expression of interferon-beta.

J Biol Chem 2003 Mar 23;278(10):8018-27. Epub 2002 Dec 23.

Department of Molecular and Medical Pharmacology, UCLA, Los Angeles, California 90095, USA.

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http://dx.doi.org/10.1074/jbc.M211642200DOI Listing
March 2003

Myocyte and endothelial effects of preconditioning the jeopardized heart by inhibiting Na/H exchange.

J Thorac Cardiovasc Surg 2002 Dec;124(6):1113-21

Department of Surgery, Division of Cardiothoracic Surgery, and the Department of Physiology, University of California, Los Angeles, School of Medicine, Los Angeles, CA 90095-1701, USA.

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http://dx.doi.org/10.1067/mtc.2002.125485DOI Listing
December 2002