Lou Brundin

Lou Brundin

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Lou Brundin

Lou Brundin

Publications by authors named "Lou Brundin"

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Retinal nerve fiber layer thickness associates with cognitive impairment and physical disability in multiple sclerosis.

Mult Scler Relat Disord 2019 Sep 26;36:101414. Epub 2019 Sep 26.

Unit of Optometry, Department of Clinical Neuroscience, Karolinska Institutet, Box 8056, S-104 20 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.msard.2019.101414DOI Listing
September 2019

Myelin oligodendrocyte glycoprotein revisited-sensitive detection of MOG-specific T-cells in multiple sclerosis.

J Autoimmun 2019 Aug 1;102:38-49. Epub 2019 May 1.

Therapeutic Immune Design, Department of Clinical Neuroscience, Karolinska Institutet, Center for Molecular Medicine L8:02, 171 76, Stockholm, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08968411193003
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http://dx.doi.org/10.1016/j.jaut.2019.04.013DOI Listing
August 2019

Epidemiology of NMOSD in Sweden from 1987 to 2013: A nationwide population-based study.

Neurology 2019 Jul 6;93(2):e181-e189. Epub 2019 Jun 6.

From the Department of Neurology (D.I.J., O.S., L.B.), Karolinska University Hospital; and Department of Clinical Neuroscience (O.S., R.H.), Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1212/WNL.0000000000007746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656652PMC
July 2019

Endogenous spinal cord stem cells in multiple sclerosis and its animal model.

J Neuroimmunol 2019 Jun 15;331:4-10. Epub 2016 Nov 15.

Department of Clinical Neuroscience, Division of Neurology R3:04, Center of Molecular Medicine, L8:04, Karolinska Institutet, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2016.11.006DOI Listing
June 2019

Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis.

JAMA Neurol 2019 Jun 17. Epub 2019 Jun 17.

UCL Institute of Neurology, Queen Square, London, United Kingdom.

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http://dx.doi.org/10.1001/jamaneurol.2019.1534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580449PMC
June 2019

Adult Neural Progenitor Cells Transplanted into Spinal Cord Injury Differentiate into Oligodendrocytes, Enhance Myelination, and Contribute to Recovery.

Stem Cell Reports 2019 May 25;12(5):950-966. Epub 2019 Apr 25.

Department of Clinical Neuroscience, Karolinska Institutet, 17177 Stockholm, Sweden; Center of Molecular Medicine, Karolinska Institutet, 17177 Stockholm, Sweden; Departments of Neurology and Neurosurgery, Karolinska University Hospital, 17176 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2019.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524946PMC
May 2019

Neuronal methylome reveals CREB-associated neuro-axonal impairment in multiple sclerosis.

Clin Epigenetics 2019 May 30;11(1):86. Epub 2019 May 30.

Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s13148-019-0678-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543588PMC
May 2019

Syngeneic, in contrast to allogeneic, mesenchymal stem cells have superior therapeutic potential following spinal cord injury.

J Neuroimmunol 2019 Mar 16;328:5-19. Epub 2018 Nov 16.

Department of Neurology and Neurosurgery, Karolinska University Hospital, BioClinicum, Solnavägen 30, Solna, Stockholm 17176, Sweden; Center for Molecular Medicine, Karolinska Institutet, Solna 17176, Stockholm, Sweden; Department of Clinical Neuroscience, Karolinska Institutet, Solna 17176, Stockholm, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01655728183045
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http://dx.doi.org/10.1016/j.jneuroim.2018.11.005DOI Listing
March 2019

Dynamics of oligodendrocyte generation in multiple sclerosis.

Nature 2019 02 23;566(7745):538-542. Epub 2019 Jan 23.

Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41586-018-0842-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420067PMC
February 2019

Publisher Correction: Dynamics of oligodendrocyte generation in multiple sclerosis.

Nature 2019 02;566(7744):E9

Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41586-019-0935-7DOI Listing
February 2019

Mass spectrometry-based analysis of cerebrospinal fluid from arthritis patients-immune-related candidate proteins affected by TNF blocking treatment.

Arthritis Res Ther 2019 Feb 15;21(1):60. Epub 2019 Feb 15.

Rheumatology Unit, Department of Medicine, Solna, Center of Molecular Medicine (CMM), Karolinska Institutet, Karolinska University Hospital, SE-17176, Stockholm, Sweden.

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https://arthritis-research.biomedcentral.com/articles/10.118
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http://dx.doi.org/10.1186/s13075-019-1846-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377734PMC
February 2019

The national incidence of PML in Sweden, 1988-2013.

Neurology 2018 02 10;90(6):e498-e506. Epub 2018 Jan 10.

From the Department of Clinical Neuroscience, Division of Neurology (E.I., R.H., T.O., L.B.), Neuroimmunology Unit, Center for Molecular Medicine, Department of Clinical Neuroscience (T.O., L.B.), and Center for Pharmacoepidemiology (S. Burkill, S. Bahmanyar, C.B.) and Clinical Epidemiology Unit (M.F., S.M.), Department of Medicine, Solna, Karolinska Institutet, Stockholm; Clinical Epidemiology and Biostatistics (S.M.), School of Medical Sciences, Örebro University, Sweden; and Department of Epidemiology and Public Health (S.M.), University College London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000004926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5818018PMC
February 2018

Effects of Neuroinflammation on Neural Stem Cells.

Neuroscientist 2017 Feb 7;23(1):27-39. Epub 2016 Jul 7.

1 Depatment of Clinical Neuroscience, Neurology, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden.

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http://nro.sagepub.com/content/early/2015/12/08/107385841561
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http://nro.sagepub.com/cgi/doi/10.1177/1073858415616559
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http://dx.doi.org/10.1177/1073858415616559DOI Listing
February 2017

CSF examination still has value in the diagnosis of MS-YES.

Authors:
Lou Brundin

Mult Scler 2016 07 8;22(8):994-5. Epub 2016 Apr 8.

Neuroimmunology, Department of Clinical Neuroscience, Karolinska Institutet, R3:04, Karolinska University Hospital, Stockholm, Sweden

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http://dx.doi.org/10.1177/1352458516642853DOI Listing
July 2016

Circulating miR-150 in CSF is a novel candidate biomarker for multiple sclerosis.

Neurol Neuroimmunol Neuroinflamm 2016 Jun 20;3(3):e219. Epub 2016 Apr 20.

Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1212/NXI.0000000000000219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841644PMC
June 2016

Cell Fusion along the Anterior-Posterior Neuroaxis in Mice with Experimental Autoimmune Encephalomyelitis.

PLoS One 2015 24;10(7):e0133903. Epub 2015 Jul 24.

Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden; Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Public Dental Service at Gällö, Jämtland Härjedalen County Council, Gällö, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0133903PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4514791PMC
May 2016

Adjuvant Stereotactic Radiosurgery Reduces Need for Retreatments in Patients with Meningioma Residuals.

World Neurosurg 2016 Apr 4;88:475-82. Epub 2015 Nov 4.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; Department of Neurosurgery, Karolinska University Hospital, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.wneu.2015.10.062DOI Listing
April 2016

Dynamics of oligodendrocyte generation and myelination in the human brain.

Cell 2014 Nov;159(4):766-74

Department of Cell and Molecular Biology, Karolinska Institutet, 171 77 Stockholm, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674140129
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http://dx.doi.org/10.1016/j.cell.2014.10.011DOI Listing
November 2014

Oxidative stress increases neurogenesis and oligodendrogenesis in adult neural progenitor cells.

Stem Cells Dev 2014 Oct 18;23(19):2311-27. Epub 2014 Jun 18.

1 Neurology Unit, Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital , Stockholm, Sweden .

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http://dx.doi.org/10.1089/scd.2013.0452DOI Listing
October 2014

Nitric oxide-induced neuronal to glial lineage fate-change depends on NRSF/REST function in neural progenitor cells.

Stem Cells 2014 Sep;32(9):2539-49

Division of Neurology , Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden; Division of Neurosurgery, Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1002/stem.1749DOI Listing
September 2014

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis.

Authors:
Ashley H Beecham Nikolaos A Patsopoulos Dionysia K Xifara Mary F Davis Anu Kemppinen Chris Cotsapas Tejas S Shah Chris Spencer David Booth An Goris Annette Oturai Janna Saarela Bertrand Fontaine Bernhard Hemmer Claes Martin Frauke Zipp Sandra D'Alfonso Filippo Martinelli-Boneschi Bruce Taylor Hanne F Harbo Ingrid Kockum Jan Hillert Tomas Olsson Maria Ban Jorge R Oksenberg Rogier Hintzen Lisa F Barcellos Cristina Agliardi Lars Alfredsson Mehdi Alizadeh Carl Anderson Robert Andrews Helle Bach Søndergaard Amie Baker Gavin Band Sergio E Baranzini Nadia Barizzone Jeffrey Barrett Céline Bellenguez Laura Bergamaschi Luisa Bernardinelli Achim Berthele Viola Biberacher Thomas M C Binder Hannah Blackburn Izaura L Bomfim Paola Brambilla Simon Broadley Bruno Brochet Lou Brundin Dorothea Buck Helmut Butzkueven Stacy J Caillier William Camu Wassila Carpentier Paola Cavalla Elisabeth G Celius Irène Coman Giancarlo Comi Lucia Corrado Leentje Cosemans Isabelle Cournu-Rebeix Bruce A C Cree Daniele Cusi Vincent Damotte Gilles Defer Silvia R Delgado Panos Deloukas Alessia di Sapio Alexander T Dilthey Peter Donnelly Bénédicte Dubois Martin Duddy Sarah Edkins Irina Elovaara Federica Esposito Nikos Evangelou Barnaby Fiddes Judith Field Andre Franke Colin Freeman Irene Y Frohlich Daniela Galimberti Christian Gieger Pierre-Antoine Gourraud Christiane Graetz Andrew Graham Verena Grummel Clara Guaschino Athena Hadjixenofontos Hakon Hakonarson Christopher Halfpenny Gillian Hall Per Hall Anders Hamsten James Harley Timothy Harrower Clive Hawkins Garrett Hellenthal Charles Hillier Jeremy Hobart Muni Hoshi Sarah E Hunt Maja Jagodic Ilijas Jelčić Angela Jochim Brian Kendall Allan Kermode Trevor Kilpatrick Keijo Koivisto Ioanna Konidari Thomas Korn Helena Kronsbein Cordelia Langford Malin Larsson Mark Lathrop Christine Lebrun-Frenay Jeannette Lechner-Scott Michelle H Lee Maurizio A Leone Virpi Leppä Giuseppe Liberatore Benedicte A Lie Christina M Lill Magdalena Lindén Jenny Link Felix Luessi Jan Lycke Fabio Macciardi Satu Männistö Clara P Manrique Roland Martin Vittorio Martinelli Deborah Mason Gordon Mazibrada Cristin McCabe Inger-Lise Mero Julia Mescheriakova Loukas Moutsianas Kjell-Morten Myhr Guy Nagels Richard Nicholas Petra Nilsson Fredrik Piehl Matti Pirinen Siân E Price Hong Quach Mauri Reunanen Wim Robberecht Neil P Robertson Mariaemma Rodegher David Rog Marco Salvetti Nathalie C Schnetz-Boutaud Finn Sellebjerg Rebecca C Selter Catherine Schaefer Sandip Shaunak Ling Shen Simon Shields Volker Siffrin Mark Slee Per Soelberg Sorensen Melissa Sorosina Mireia Sospedra Anne Spurkland Amy Strange Emilie Sundqvist Vincent Thijs John Thorpe Anna Ticca Pentti Tienari Cornelia van Duijn Elizabeth M Visser Steve Vucic Helga Westerlind James S Wiley Alastair Wilkins James F Wilson Juliane Winkelmann John Zajicek Eva Zindler Jonathan L Haines Margaret A Pericak-Vance Adrian J Ivinson Graeme Stewart David Hafler Stephen L Hauser Alastair Compston Gil McVean Philip De Jager Stephen J Sawcer Jacob L McCauley

Nat Genet 2013 Nov 29;45(11):1353-60. Epub 2013 Sep 29.

1] John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine, Miami, Florida, USA. [2].

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http://dx.doi.org/10.1038/ng.2770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832895PMC
November 2013

Neural stem/progenitor cells transplanted to the hypoglossal nucleus integrates with the host CNS in adult rats and promotes motor neuron survival.

Cell Transplant 2012 13;21(4):739-47. Epub 2011 Dec 13.

Department of Clinical Neuroscience and Departments of Neurosurgery and Neurology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.3727/096368911X612459DOI Listing
June 2013

Distribution and characterization of progenitor cells within the human filum terminale.

PLoS One 2011 11;6(11):e27393. Epub 2011 Nov 11.

Department of Clinical Neuroscience, Dept of Neurosurgery and Neurology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0027393PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214055PMC
April 2012

Proliferation, migration and differentiation of ependymal region neural progenitor cells in the brainstem after hypoglossal nerve avulsion.

Restor Neurol Neurosci 2011 ;29(1):47-59

Department of Clinical Neuroscience, Department of Neurosurgery and Neurology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.

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http://www.medra.org/servlet/aliasResolver?alias=iospress&am
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http://dx.doi.org/10.3233/RNN-2011-0578DOI Listing
January 2012

Cerebrospinal fluid CXCL13 in multiple sclerosis: a suggestive prognostic marker for the disease course.

Mult Scler 2011 Mar 6;17(3):335-43. Epub 2010 Dec 6.

Department of Clinical Neuroscience, Neuroimmunology Unit, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1177/1352458510389102DOI Listing
March 2011

Levels of nitric oxide metabolites in cerebrospinal fluid in cluster headache.

Cephalalgia 2010 Jun 10;30(6):696-702. Epub 2010 Mar 10.

Karolinska Institute, Sweden.

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http://dx.doi.org/10.1177/0333102409351799DOI Listing
June 2010

TLR activation induces TNF-alpha production from adult neural stem/progenitor cells.

J Immunol 2009 Jun;182(11):6889-95

Department of Clinical Neurosciences, Division of Neuroimmunology, Division of Rheumatology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.4049/jimmunol.0802907DOI Listing
June 2009

Pivotal advance: HMGB1 expression in active lesions of human and experimental multiple sclerosis.

J Leukoc Biol 2008 Nov 21;84(5):1248-55. Epub 2008 Jul 21.

Department of Clinical Neurosciences, Neuroimmunology Unit, Karolinska University Hospital at Solna, Karolinska Institutet, Stockholm, Sweden.

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http://doi.wiley.com/10.1189/jlb.1207844
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http://dx.doi.org/10.1189/jlb.1207844DOI Listing
November 2008

Nitric oxide exposure diverts neural stem cell fate from neurogenesis towards astrogliogenesis.

Stem Cells 2006 Dec 17;24(12):2792-800. Epub 2006 Aug 17.

Department of Clinical Neuroscience, Division of Neurology, Neuroimmunology Unit, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1634/stemcells.2005-0640DOI Listing
December 2006

Neuroprotection by selective inhibition of inducible nitric oxide synthase after experimental brain contusion.

J Neurotrauma 2006 Sep;23(9):1343-54

Department of Clinical Neuroscience, Section of Clinical CNS Research, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1089/neu.2006.23.1343DOI Listing
September 2006

Neurogenesis in the adult spinal cord in an experimental model of multiple sclerosis.

Eur J Neurosci 2006 Jan;23(2):394-400

Department of Clinical Neuroscience, Karolinska Instiutet, Sweden.

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http://dx.doi.org/10.1111/j.1460-9568.2005.04563.xDOI Listing
January 2006

Reduced neuronal injury after treatment with NG-nitro-L-arginine methyl ester (L-NAME) or 2-sulfo-phenyl-N-tert-butyl nitrone (S-PBN) following experimental brain contusion.

Neurosurgery 2005 Dec;57(6):1272-81; discussion 1272-81

Department of Clinical Neuroscience, Section of Clinical CNS Research, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1227/01.neu.0000187317.32529.06DOI Listing
December 2005

Effects of long term NOS inhibition on disease and the immune system in MOG induced EAE.

Nitric Oxide 2005 Nov 15;13(3):188-95. Epub 2005 Aug 15.

Department of Clinical Neuroscience, Division of Neurology, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.niox.2005.06.007DOI Listing
November 2005

Multipotent progenitor cells from the adult human brain: neurophysiological differentiation to mature neurons.

Brain 2005 Sep 15;128(Pt 9):2189-99. Epub 2005 Jun 15.

Department of Clinical Neuroscience, Karolinska Institutet, 171 76 Stockholm, Sweden.

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http://dx.doi.org/10.1093/brain/awh574DOI Listing
September 2005

Neural stem cells: a potential source for remyelination in neuroinflammatory disease.

Brain Pathol 2003 Jul;13(3):322-8

Neuroimmunology Unit, Centre of Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.

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July 2003

Nitric oxide metabolite determinations reveal continuous inflammation in multiple sclerosis.

J Neuroimmunol 2003 Mar;136(1-2):112-8

Department of Clinical Neuroscience, Karolinska Institutet, Karolinska Hospital, S-17176 Stockholm, Sweden.

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http://dx.doi.org/10.1016/s0165-5728(02)00464-2DOI Listing
March 2003