Publications by authors named "Lothar Seefried"

27Publications

Differential impact of osteoporosis, sarcopenia and obesity on physical performance in aging men.

Authors:
Franca Genest Michael Schneider Andreas Zehnder Dominik Lieberoth-Leden Lothar Seefried

Endocr Connect 2021 Jan 1. Epub 2021 Jan 1.

L Seefried, Orthopedic Department, Julius Maximilians University Würzburg, Wurzburg, Germany.

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January 2021

Impact of whole-body vibration exercise on physical performance and bone turnover in patients with monoclonal gammopathy of undetermined significance.

Authors:
Lothar Seefried Franca Genest Johanna Strömsdörfer Bernhard Engelmann Constantin Lapa Franz Jakob Freerk T Baumann Billy Sperlich Franziska Jundt

J Bone Oncol 2020 Dec 28;25:100323. Epub 2020 Sep 28.

Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany.

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December 2020

Physical Function and Health-Related Quality of Life in Adults Treated With Asfotase Alfa for Pediatric-Onset Hypophosphatasia.

Authors:
Franca Genest Dominik Rak Anna Petryk Lothar Seefried

JBMR Plus 2020 Sep 4;4(9):e10395. Epub 2020 Aug 4.

Orthopedic Department University of Würzburg Würzburg Germany.

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September 2020

Pharmacodynamics of asfotase alfa in adults with pediatric-onset hypophosphatasia.

Authors:
Lothar Seefried Priya S Kishnani Scott Moseley Andrew E Denker Eric Watsky Michael P Whyte Kathryn M Dahir

Bone 2021 Jan 26;142:115664. Epub 2020 Sep 26.

Program for Metabolic Bone Disorders at Vanderbilt, Division of Diabetes and Endocrinology, Vanderbilt University Medical Center, Nashville, TN, USA.

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January 2021

Penetration of topical diclofenac into synovial tissue and fluid of osteoarthritic knees: a multicenter, randomized, placebo-controlled, pharmacokinetic study.

Authors:
Lothar Seefried Mark Blyth Rohit Maheshwari Stephen M McDonnell Guillaume Frappin Martina Hagen Nadine Maybaum Sebastian Moreira Hemant Pandit

Ther Adv Musculoskelet Dis 2020 29;12:1759720X20943088. Epub 2020 Aug 29.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Chapel Allerton Hospital, Leeds, UK.

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August 2020

Pediatric hypophosphatasia: lessons learned from a retrospective single-center chart review of 50 children.

Authors:
Marius Vogt Hermann Girschick Tilmann Schweitzer Clemens Benoit Annette Holl-Wieden Lothar Seefried Franz Jakob Christine Hofmann

Orphanet J Rare Dis 2020 08 18;15(1):212. Epub 2020 Aug 18.

Pediatric Rheumatology and Osteology, University Children's Hospital Wuerzburg, Wuerzburg, Germany.

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August 2020

Burden of Illness in Adults With Hypophosphatasia: Data From the Global Hypophosphatasia Patient Registry.

Authors:
Lothar Seefried Kathryn Dahir Anna Petryk Wolfgang Högler Agnès Linglart Gabriel Ángel Martos-Moreno Keiichi Ozono Shona Fang Cheryl Rockman-Greenberg Priya S Kishnani

J Bone Miner Res 2020 Nov 10;35(11):2171-2178. Epub 2020 Aug 10.

Division of Medical Genetics, Department of Pediatrics, Duke University Medical Center, Durham, NC, USA.

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November 2020

Mineral Intake and Clinical Symptoms in Adult Patients with Hypophosphatasia.

Authors:
Katinka Kuehn Andreas Hahn Lothar Seefried

J Clin Endocrinol Metab 2020 Aug;105(8)

Clinical Trial Unit, Orthopedic Institute, Koenig-Ludwig-Haus, University of Wuerzburg, Wuerzburg, Germany.

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August 2020

Diagnostic delay is common among patients with hypophosphatasia: initial findings from a longitudinal, prospective, global registry.

Authors:
Wolfgang Högler Craig Langman Hugo Gomes da Silva Shona Fang Agnès Linglart Keiichi Ozono Anna Petryk Cheryl Rockman-Greenberg Lothar Seefried Priya S Kishnani

BMC Musculoskelet Disord 2019 Feb 14;20(1):80. Epub 2019 Feb 14.

Department of Pediatrics, Duke University Medical Center, 2301 Erwin Rd, Durham, NC, 27710, USA.

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February 2019

Physical contact between mesenchymal stem cells and endothelial precursors induces distinct signatures with relevance to the very early phase of regeneration.

Authors:
Bettina Hafen Susanne Wiesner Katrin Schlegelmilch Alexander Keller Lothar Seefried Regina Ebert Heike Walles Franz Jakob Norbert Schütze

J Cell Biochem 2018 11 13;119(11):9122-9140. Epub 2018 Aug 13.

Orthopedic Clinic, Orthopedic Center for Musculoskeletal Research, University of Würzburg, Germany.

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November 2018

Cellular pharmacodynamic effects of Pycnogenol® in patients with severe osteoarthritis: a randomized controlled pilot study.

Authors:
Steffen Jessberger Petra Högger Franca Genest Donald M Salter Lothar Seefried

BMC Complement Altern Med 2017 Dec 16;17(1):537. Epub 2017 Dec 16.

Department of Orthopedics, Universität Würzburg, Orthopedic Center for Musculoskeletal Research, Brettreichstraße 11, 97074, Würzburg, Germany.

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December 2017

Primary Osteoporosis Is Not Reflected by Disease-Specific DNA Methylation or Accelerated Epigenetic Age in Blood.

Authors:
Eduardo Fernandez-Rebollo Monika Eipel Lothar Seefried Per Hoffmann Klaus Strathmann Franz Jakob Wolfgang Wagner

J Bone Miner Res 2018 02 23;33(2):356-361. Epub 2017 Oct 23.

Helmholtz-Institute for Biomedical Engineering, Stem Cell Biology and Cellular Engineering, Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen University Medical School, Aachen, Germany.

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February 2018

Monitoring guidance for patients with hypophosphatasia treated with asfotase alfa.

Authors:
Priya S Kishnani Eric T Rush Paul Arundel Nick Bishop Kathryn Dahir William Fraser Paul Harmatz Agnès Linglart Craig F Munns Mark E Nunes Howard M Saal Lothar Seefried Keiichi Ozono

Mol Genet Metab 2017 09 25;122(1-2):4-17. Epub 2017 Jul 25.

Department of Pediatrics, Osaka University, Suita, Osaka 565-0871, Japan.

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September 2017

Epidermal growth factor as a mechanosensitizer in human bone marrow stromal cells.

Authors:
Sigrid Müller-Deubert Lothar Seefried Melanie Krug Franz Jakob Regina Ebert

Stem Cell Res 2017 10 18;24:69-76. Epub 2017 Aug 18.

Orthopedic Center for Musculoskeletal Research, Orthopedic Department, University of Würzburg, Friedrich-Bergius-Ring 15, 97076 Würzburg, Germany.

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October 2017

Distribution of Constituents and Metabolites of Maritime Pine Bark Extract (Pycnogenol) into Serum, Blood Cells, and Synovial Fluid of Patients with Severe Osteoarthritis: A Randomized Controlled Trial.

Authors:
Melanie Mülek Lothar Seefried Franca Genest Petra Högger

Nutrients 2017 Apr 28;9(5). Epub 2017 Apr 28.

Institut für Pharmazie und Lebensmittelchemie, Universität Würzburg, 97074 Würzburg, Germany.

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April 2017

Efficacy of anti-sclerostin monoclonal antibody BPS804 in adult patients with hypophosphatasia.

Authors:
Lothar Seefried Jasmin Baumann Sarah Hemsley Christine Hofmann Erdmute Kunstmann Beate Kiese Yue Huang Simon Chivers Marie-Anne Valentin Babul Borah Ronenn Roubenoff Uwe Junker Franz Jakob

J Clin Invest 2017 Jun 24;127(6):2148-2158. Epub 2017 Apr 24.

Orthopedic Center of Musculoskeletal Research, Orthopedic Department, University of Würzburg, Würzburg, Germany.

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June 2017

BPS804 Anti-Sclerostin Antibody in Adults With Moderate Osteogenesis Imperfecta: Results of a Randomized Phase 2a Trial.

Authors:
Francis H Glorieux Jean-Pierre Devogelaer Michaela Durigova Stefan Goemaere Sarah Hemsley Franz Jakob Uwe Junker Jon Ruckle Lothar Seefried Peter J Winkle

J Bone Miner Res 2017 Jul 19;32(7):1496-1504. Epub 2017 Apr 19.

Anaheim Clinical Trials, Anaheim, CA, USA.

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July 2017

High Prevalence of Vitamin D Deficiency in Patients With Bone Marrow Edema Syndrome of the Foot and Ankle.

Authors:
Konstantin Horas Lukas Fraissler Gerrit Maier Franz Jakob Lothar Seefried Christian Konrads Maximilian Rudert Matthias Walcher

Foot Ankle Int 2017 Jul 24;38(7):760-766. Epub 2017 Mar 24.

1 Department of Orthopedics, Koenig-Ludwig-Haus, University of Wuerzburg, Wuerzburg, Germany.

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July 2017

Dissection of mechanoresponse elements in promoter sites of the mechanoresponsive CYR61 gene.

Authors:
Lothar Seefried Sigrid Müller-Deubert Melanie Krug Almoatazbellah Youssef Norbert Schütze Anita Ignatius Franz Jakob Regina Ebert

Exp Cell Res 2017 05 16;354(2):103-111. Epub 2017 Mar 16.

Orthopedic Center for Musculoskeletal Research, Orthopedic Department, University of Würzburg, Friedrich-Bergius-Ring 15, 97076 Würzburg, Germany. Electronic address:

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May 2017

Recombinant Enzyme Replacement Therapy in Hypophosphatasia.

Authors:
Christine Hofmann Franz Jakob Lothar Seefried Birgit Mentrup Stephanie Graser Horacio Plotkin Hermann J Girschick Johannes Liese

Subcell Biochem 2015 ;76:323-41

Children's Hospital, University of Würzburg, Josef-Schneider-Str. 2, 97090, Würzburg, Germany,

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January 2016