Publications by authors named "Lothar Seefried"

27Publications

Differential impact of osteoporosis, sarcopenia and obesity on physical performance in aging men.

Endocr Connect 2021 Jan 1. Epub 2021 Jan 1.

L Seefried, Orthopedic Department, Julius Maximilians University Würzburg, Wurzburg, Germany.

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January 2021

Physical Function and Health-Related Quality of Life in Adults Treated With Asfotase Alfa for Pediatric-Onset Hypophosphatasia.

JBMR Plus 2020 Sep 4;4(9):e10395. Epub 2020 Aug 4.

Orthopedic Department University of Würzburg Würzburg Germany.

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September 2020

Pharmacodynamics of asfotase alfa in adults with pediatric-onset hypophosphatasia.

Bone 2021 Jan 26;142:115664. Epub 2020 Sep 26.

Program for Metabolic Bone Disorders at Vanderbilt, Division of Diabetes and Endocrinology, Vanderbilt University Medical Center, Nashville, TN, USA.

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January 2021

Penetration of topical diclofenac into synovial tissue and fluid of osteoarthritic knees: a multicenter, randomized, placebo-controlled, pharmacokinetic study.

Ther Adv Musculoskelet Dis 2020 29;12:1759720X20943088. Epub 2020 Aug 29.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Chapel Allerton Hospital, Leeds, UK.

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August 2020

Pediatric hypophosphatasia: lessons learned from a retrospective single-center chart review of 50 children.

Orphanet J Rare Dis 2020 08 18;15(1):212. Epub 2020 Aug 18.

Pediatric Rheumatology and Osteology, University Children's Hospital Wuerzburg, Wuerzburg, Germany.

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August 2020

Burden of Illness in Adults With Hypophosphatasia: Data From the Global Hypophosphatasia Patient Registry.

J Bone Miner Res 2020 Nov 10;35(11):2171-2178. Epub 2020 Aug 10.

Division of Medical Genetics, Department of Pediatrics, Duke University Medical Center, Durham, NC, USA.

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November 2020

Mineral Intake and Clinical Symptoms in Adult Patients with Hypophosphatasia.

J Clin Endocrinol Metab 2020 Aug;105(8)

Clinical Trial Unit, Orthopedic Institute, Koenig-Ludwig-Haus, University of Wuerzburg, Wuerzburg, Germany.

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August 2020

Cellular pharmacodynamic effects of Pycnogenol® in patients with severe osteoarthritis: a randomized controlled pilot study.

BMC Complement Altern Med 2017 Dec 16;17(1):537. Epub 2017 Dec 16.

Department of Orthopedics, Universität Würzburg, Orthopedic Center for Musculoskeletal Research, Brettreichstraße 11, 97074, Würzburg, Germany.

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December 2017

Primary Osteoporosis Is Not Reflected by Disease-Specific DNA Methylation or Accelerated Epigenetic Age in Blood.

J Bone Miner Res 2018 02 23;33(2):356-361. Epub 2017 Oct 23.

Helmholtz-Institute for Biomedical Engineering, Stem Cell Biology and Cellular Engineering, Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen University Medical School, Aachen, Germany.

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February 2018

Epidermal growth factor as a mechanosensitizer in human bone marrow stromal cells.

Stem Cell Res 2017 10 18;24:69-76. Epub 2017 Aug 18.

Orthopedic Center for Musculoskeletal Research, Orthopedic Department, University of Würzburg, Friedrich-Bergius-Ring 15, 97076 Würzburg, Germany.

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October 2017

Efficacy of anti-sclerostin monoclonal antibody BPS804 in adult patients with hypophosphatasia.

J Clin Invest 2017 Jun 24;127(6):2148-2158. Epub 2017 Apr 24.

Orthopedic Center of Musculoskeletal Research, Orthopedic Department, University of Würzburg, Würzburg, Germany.

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June 2017

High Prevalence of Vitamin D Deficiency in Patients With Bone Marrow Edema Syndrome of the Foot and Ankle.

Foot Ankle Int 2017 Jul 24;38(7):760-766. Epub 2017 Mar 24.

1 Department of Orthopedics, Koenig-Ludwig-Haus, University of Wuerzburg, Wuerzburg, Germany.

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July 2017

Dissection of mechanoresponse elements in promoter sites of the mechanoresponsive CYR61 gene.

Exp Cell Res 2017 05 16;354(2):103-111. Epub 2017 Mar 16.

Orthopedic Center for Musculoskeletal Research, Orthopedic Department, University of Würzburg, Friedrich-Bergius-Ring 15, 97076 Würzburg, Germany. Electronic address:

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May 2017

Recombinant Enzyme Replacement Therapy in Hypophosphatasia.

Subcell Biochem 2015 ;76:323-41

Children's Hospital, University of Würzburg, Josef-Schneider-Str. 2, 97090, Würzburg, Germany,

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January 2016