Publications by authors named "Lothar Rink"

128Publications

Increase of the Intracellular Zinc Concentration Leads to an Activation and Internalisation of the Epidermal Growth Factor Receptor in A549 Cells.

Int J Mol Sci 2020 Dec 30;22(1). Epub 2020 Dec 30.

Institute of Immunology, Medical Faculty, RWTH Aachen University, Pauwelsstraße 30, D-52074 Aachen, Germany.

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December 2020

Update on the multi-layered levels of zinc-mediated immune regulation.

Semin Cell Dev Biol 2020 Dec 12. Epub 2020 Dec 12.

Institute of Immunology, Faculty of Medicine, RWTH Aachen University, Pauwelsstr. 30, 52074 Aachen, Germany. Electronic address:

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December 2020

Zinc deficiency leads to reduced interleukin-2 production by active gene silencing due to enhanced CREMα expression in T cells.

Clin Nutr 2020 Oct 30. Epub 2020 Oct 30.

Institute of Immunology, Faculty of Medicine, RWTH Aachen University, Pauwelsstr. 30, 52074, Aachen, Germany. Electronic address:

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October 2020

The Potential Impact of Zinc Supplementation on COVID-19 Pathogenesis.

Front Immunol 2020;11:1712. Epub 2020 Jul 10.

Institute of Immunology, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.

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August 2020

Zinc deficiency impairs interferon-γ production on post-transcriptional level.

J Trace Elem Med Biol 2020 Dec 23;62:126598. Epub 2020 Jun 23.

Institute of Immunology, Medical Faculty, RWTH Aachen University, Pauwelsstr. 30, D-52074 Aachen, Germany. Electronic address:

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December 2020

Closed-Tube Multiplex Real-Time PCR for the Detection of Group A Streptococcal Superantigens.

Methods Mol Biol 2020 ;2136:17-23

Institute of Immunology, Faculty of Medicine, RWTH Aachen University, University Hospital, Aachen, Germany.

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January 2020

Zinc supplementation ameliorates lung injury by reducing neutrophil recruitment and activity.

Thorax 2020 03 8;75(3):253-261. Epub 2020 Jan 8.

Department of Vascular Surgery, Medical Faculty, RWTH Aachen University, Aachen, Nordrhein-Westfalen, Germany

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March 2020

The Interaction of Sodium and Zinc in the Priming of T Cell Subpopulations Regarding Th17 and Treg Cells.

Mol Nutr Food Res 2020 01 7;64(2):e1900245. Epub 2020 Jan 7.

Institute of Immunology, Faculty of Medicine, University Hospital RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Germany.

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January 2020

Micronutrients in autoimmune diseases: possible therapeutic benefits of zinc and vitamin D.

J Nutr Biochem 2020 03 30;77:108240. Epub 2019 Oct 30.

Institute of Immunology, Medical Faculty, RWTH Aachen University, Pauwelsstr. 30, D-52074 Aachen, Germany. Electronic address:

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March 2020

Selection of an inadequate housekeeping gene leads to misinterpretation of target gene expression in zinc deficiency and zinc supplementation models.

J Trace Elem Med Biol 2019 Dec 20;56:192-197. Epub 2019 Aug 20.

Institute of Immunology, Faculty of Medicine, RWTH Aachen University, Pauwelsstr. 30, 52074 Aachen, Germany. Electronic address:

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December 2019

Zinc supplementation improves glycemic control for diabetes prevention and management: a systematic review and meta-analysis of randomized controlled trials.

Am J Clin Nutr 2019 07;110(1):76-90

The First Affiliated Hospital, School of Public Health, Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, China.

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July 2019

Alterations in membrane fluidity are involved in inhibition of GM-CSF-induced signaling in myeloid cells by zinc.

J Trace Elem Med Biol 2019 Jul 2;54:214-220. Epub 2019 May 2.

Institute of Immunology, Medical Faculty, RWTH Aachen University, Pauwelsstr. 30, D-52074 Aachen, Germany. Electronic address:

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July 2019

The human allicin-proteome: S-thioallylation of proteins by the garlic defence substance allicin and its biological effects.

Free Radic Biol Med 2019 02 27;131:144-153. Epub 2018 Nov 27.

Department of Plant Physiology, RWTH Aachen University, Worringer Weg 1, D-52056 Aachen, Germany.

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February 2019

B cell activation and proliferation increase intracellular zinc levels.

J Nutr Biochem 2019 02 26;64:72-79. Epub 2018 Oct 26.

Institute of Immunology, Faculty of Medicine, RWTH Aachen University Hospital, Pauwelsstr. 30, 52074 Aachen, Germany. Electronic address:

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February 2019

The Intracellular Free Zinc Level Is Vital for Treg Function and a Feasible Tool to Discriminate between Treg and Activated Th Cells.

Int J Mol Sci 2018 Nov 13;19(11). Epub 2018 Nov 13.

Institute of Immunology, RWTH Aachen University Hospital, Pauwelsstr. 30, 52074 Aachen, Germany.

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November 2018

Experimental peri-implant mucositis around titanium and zirconia implants in comparison to a natural tooth: part 1-host-derived immunological parameters.

Int J Oral Maxillofac Surg 2019 Apr 5;48(4):554-559. Epub 2018 Nov 5.

Department of Oral and Cranio-Maxillofacial Surgery, University Hospital RWTH Aachen, Aachen, Germany. Electronic address:

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April 2019

Zinc deficiency drives Th17 polarization and promotes loss of Treg cell function.

J Nutr Biochem 2019 01 21;63:11-18. Epub 2018 Sep 21.

Institute of Immunology, RWTH Aachen University Hospital, Pauwelsstr. 30, 52074 Aachen, Germany. Electronic address:

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January 2019

Editorial GMS special issue.

J Trace Elem Med Biol 2018 12 3;50:367. Epub 2018 Aug 3.

Institute of Immunology, Pauwelsstr. 30, D-52074 Aachen, Germany.

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December 2018