Lori A Walker

Lori A Walker

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Lori A Walker

Lori A Walker

Publications by authors named "Lori A Walker"

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The right ventricular fibroblast secretome drives cardiomyocyte dedifferentiation.

PLoS One 2019 2;14(8):e0220573. Epub 2019 Aug 2.

University of Colorado-Denver, Dept. of Medicine/Cardiology, Aurora, CO, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0220573PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677314PMC
March 2020

Increased myocyte calcium sensitivity in end-stage pediatric dilated cardiomyopathy.

Am J Physiol Heart Circ Physiol 2019 12 18;317(6):H1221-H1230. Epub 2019 Oct 18.

Division of Cardiology, Department of Medicine, University of Colorado Denver, Aurora, Colorado.

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http://dx.doi.org/10.1152/ajpheart.00409.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6960778PMC
December 2019

Intense Light-Mediated Circadian Cardioprotection via Transcriptional Reprogramming of the Endothelium.

Cell Rep 2019 Aug;28(6):1471-1484.e11

Mucosal Inflammation Program, Departments of Medicine and Anesthesiology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Division of Cardiology, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Graduate Training Program in Cell Biology, Stem Cells, and Development, University of Colorado Anschutz Medical Campus, Aurora, CO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.07.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708043PMC
August 2019

Marijuana use and short-term outcomes in patients hospitalized for acute myocardial infarction.

PLoS One 2018 11;13(7):e0199705. Epub 2018 Jul 11.

Department of Medicine, Division of Cardiology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0199705PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040751PMC
December 2018

Exercise and Pharmacology as Medicine for Cardiovascular Diseases: From Bench to Bedside and Back.

Exerc Sport Sci Rev 2018 01;46(1):2-3

Division of Cardiology, Department of Medicine, University of Colorado-Denver, Aurora, CO.

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http://dx.doi.org/10.1249/JES.0000000000000133DOI Listing
January 2018

Semi-automated Analysis of Mouse Skeletal Muscle Morphology and Fiber-type Composition.

J Vis Exp 2017 08 31(126). Epub 2017 Aug 31.

Department of Medicine-Cardiology Division, University of Colorado School of Medicine;

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http://dx.doi.org/10.3791/56024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614392PMC
August 2017

Differential Mitochondrial Adaptation in Primary Vascular Smooth Muscle Cells from a Diabetic Rat Model.

Oxid Med Cell Longev 2016 11;2016:8524267. Epub 2016 Jan 11.

Division of Endocrinology, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA; Department of Medicine, Denver VA Medical Center, Denver, CO 80220, USA; Center for Women's Health Research, University of Colorado School of Medicine, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1155/2016/8524267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737048PMC
December 2016

Genetic ablation of interleukin-18 does not attenuate hypobaric hypoxia-induced right ventricular hypertrophy.

Am J Physiol Lung Cell Mol Physiol 2016 Mar 8;310(6):L542-50. Epub 2016 Jan 8.

Department of Medicine, Cardiology, University of Colorado-Denver, Aurora, Colorado

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http://dx.doi.org/10.1152/ajplung.00166.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4796262PMC
March 2016

Nuclear PTEN functions as an essential regulator of SRF-dependent transcription to control smooth muscle differentiation.

Nat Commun 2016 Mar 4;7:10830. Epub 2016 Mar 4.

Department of Medicine, Division of Renal Diseases and Hypertension, University of Colorado, Anschutz Medical Campus, 12700 East 19th Avenue, C281, Research Complex 2, Room 7101, Aurora, Colorado 80045, USA.

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http://dx.doi.org/10.1038/ncomms10830DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5411712PMC
March 2016

High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling.

Nat Commun 2015 Sep 10;6:8243. Epub 2015 Sep 10.

Division of Cardiology, Department of Medicine, University of Colorado School of Medicine, 12700 E. 19th Avenue, B139, Aurora, Colorado 80045, USA.

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http://dx.doi.org/10.1038/ncomms9243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579788PMC
September 2015

Mitochondrial integrity in a neonatal bovine model of right ventricular dysfunction.

Am J Physiol Lung Cell Mol Physiol 2015 Jan 21;308(2):L158-67. Epub 2014 Nov 21.

Department of Medicine, Cardiology, University of Colorado-Denver, Aurora, Colorado; and

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http://dx.doi.org/10.1152/ajplung.00270.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338944PMC
January 2015

Characterization and validation of new tools for measuring site-specific cardiac troponin I phosphorylation.

J Immunol Methods 2014 Jan 26;403(1-2):66-71. Epub 2013 Nov 26.

University of Colorado Denver, Dept. of Medicine/Cardiology, Aurora, CO 80045, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jim.2013.11.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945064PMC
January 2014

Contractile protein phosphorylation predicts human heart disease phenotypes.

Am J Physiol Heart Circ Physiol 2013 Jun 5;304(12):H1644-50. Epub 2013 Apr 5.

Division of Cardiology, Department of Medicine, University of Colorado Denver, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1152/ajpheart.00957.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680767PMC
June 2013

The right ventricle: biologic insights and response to disease: updated.

Curr Cardiol Rev 2013 Feb;9(1):73-81

University of Colorado Denver, CO, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584309PMC
http://dx.doi.org/10.2174/157340313805076296DOI Listing
February 2013

Serendipitous discovery of a novel protein signaling mechanism in heart failure.

Biochem Biophys Res Commun 2012 May 7;421(3):431-5. Epub 2012 Apr 7.

University of Colorado, Department of Medicine, Division of Cardiology, Aurora, CO 80045, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X1200594
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http://dx.doi.org/10.1016/j.bbrc.2012.03.124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351564PMC
May 2012

Temporal expression of miRNAs and mRNAs in a mouse model of myocardial infarction.

Physiol Genomics 2011 Oct 19;43(19):1087-95. Epub 2011 Jul 19.

Division of Cardiology, Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1152/physiolgenomics.00074.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217325PMC
October 2011

Biochemical and myofilament responses of the right ventricle to severe pulmonary hypertension.

Am J Physiol Heart Circ Physiol 2011 Sep 27;301(3):H832-40. Epub 2011 May 27.

Department of Medicine, University of Colorado-Denver, Aurora, Colorado 80045, USA.

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http://dx.doi.org/10.1152/ajpheart.00249.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191097PMC
September 2011

Protein kinase A changes calcium sensitivity but not crossbridge kinetics in human cardiac myofibrils.

Am J Physiol Heart Circ Physiol 2011 Jul 15;301(1):H138-46. Epub 2011 Apr 15.

Division of Cardiology, Dept. of Medicine, Univ. of Colorado, Denver, Aurora CO 80045, USA.

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http://www.physiology.org/doi/10.1152/ajpheart.00838.2010
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http://dx.doi.org/10.1152/ajpheart.00838.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129926PMC
July 2011

Enhanced myofilament responsiveness upon β-adrenergic stimulation in post-infarct remodeled myocardium.

J Mol Cell Cardiol 2011 Mar 13;50(3):487-99. Epub 2010 Dec 13.

Laboratory for Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.yjmcc.2010.12.002DOI Listing
March 2011

Tissue procurement strategies affect the protein biochemistry of human heart samples.

J Muscle Res Cell Motil 2011 Mar 24;31(5-6):309-14. Epub 2010 Dec 24.

Department of Medicine, Division of Cardiology, University of Colorado Denver, B139, 12700 E 19th Ave, Aurora, CO 80045, USA.

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http://link.springer.com/10.1007/s10974-010-9233-6
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http://dx.doi.org/10.1007/s10974-010-9233-6DOI Listing
March 2011

Stage-specific changes in myofilament protein phosphorylation following myocardial infarction in mice.

J Mol Cell Cardiol 2010 Jun 30;48(6):1180-6. Epub 2009 Sep 30.

University of Colorado Health Sciences Center, Department of Medicine/Cardiology, Aurora, CO 80045, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2009.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447307PMC
June 2010

The role of Akt/GSK-3beta signaling in familial hypertrophic cardiomyopathy.

J Mol Cell Cardiol 2009 May 21;46(5):739-47. Epub 2009 Feb 21.

Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, Campus Box 347, Boulder, Colorado 80309-0347, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2009.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2701230PMC
May 2009

Prevention of myofilament dysfunction by beta-blocker therapy in postinfarct remodeling.

Circ Heart Fail 2009 May 25;2(3):233-42. Epub 2009 Mar 25.

Department of Biochemistry, Cardiovascular Research School COEUR, Erasmus MC, University Medical Center Rotterdam, Thoraxcenter, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.108.806125DOI Listing
May 2009

Ablation of ventricular myosin regulatory light chain phosphorylation in mice causes cardiac dysfunction in situ and affects neighboring myofilament protein phosphorylation.

J Biol Chem 2009 Feb 23;284(8):5097-106. Epub 2008 Dec 23.

Department of Physiology and Biophysics and Center for Cardiovascular Research, University of Illinois at Chicago, Chicago, Illinois 60612, USA.

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http://dx.doi.org/10.1074/jbc.M807414200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2643522PMC
February 2009

The right ventricle: biologic insights and response to disease.

Curr Cardiol Rev 2009 Jan;5(1):22-8

University of Colorado Denver, USA.

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http://dx.doi.org/10.2174/157340309787048077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803284PMC
January 2009

Delivery and visualization of proteins conjugated to quantum dots in cardiac myocytes.

J Mol Cell Cardiol 2008 Dec 28;45(6):853-6. Epub 2008 Aug 28.

Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2008.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639397PMC
December 2008

Involvement of RhoA/Rho kinase signaling in protection against monocrotaline-induced pulmonary hypertension in pneumonectomized rats by dehydroepiandrosterone.

Am J Physiol Lung Cell Mol Physiol 2008 Jul 9;295(1):L71-8. Epub 2008 May 9.

Cardiovascular Pulmonary Research Laboratory, University of Colorado at Denver and Health Sciences Center, Denver, Colorado, USA.

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http://dx.doi.org/10.1152/ajplung.90251.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2494797PMC
July 2008

Frequency-dependent myofilament Ca2+ desensitization in failing rat myocardium.

J Physiol 2007 Jul 3;582(Pt 2):695-709. Epub 2007 May 3.

Department of Anesthesiology, Institute for Cardiovascular Research (ICaR-VU), VU University Medical Center (VUMC), 1081 BT Amsterdam, The Netherlands.

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http://dx.doi.org/10.1113/jphysiol.2007.134486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2075316PMC
July 2007

Left ventricular myofilament dysfunction in rat experimental hypertrophy and congestive heart failure.

Am J Physiol Heart Circ Physiol 2006 Nov 30;291(5):H2344-53. Epub 2006 Jun 30.

Dept. of Physiology & Biophysics, Univ. of Illinois at Chicago, 835 S. Wolcott (M/C 901 Chicago, IL 60612, USA.

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http://www.physiology.org/doi/10.1152/ajpheart.00541.2006
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http://dx.doi.org/10.1152/ajpheart.00541.2006DOI Listing
November 2006

The effect of myosin regulatory light chain phosphorylation on the frequency-dependent regulation of cardiac function.

J Mol Cell Cardiol 2006 Aug 30;41(2):330-9. Epub 2006 Jun 30.

Center for Cardiovascular Research, Department of Medicine, Section of Cardiology, University of Illinois at Chicago, 60612, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2006.05.012DOI Listing
August 2006

Depressed cardiac myofilament function in human diabetes mellitus.

Am J Physiol Heart Circ Physiol 2005 Dec 5;289(6):H2478-83. Epub 2005 Aug 5.

Dept. of Physiology and Biophysics, (M/C 901 College of Medicine, Univ. of Illinois at Chicago, 835 S. Wolcott Ave., Chicago, IL 60612, USA.

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http://dx.doi.org/10.1152/ajpheart.00638.2005DOI Listing
December 2005

Expression of slow skeletal troponin I in adult mouse heart helps to maintain the left ventricular systolic function during respiratory hypercapnia.

Circ Res 2005 Jul 16;97(1):70-7. Epub 2005 Jun 16.

Center for Cardiovascular Research, Department of Physiology and Biophysics, Section of Cardiology, University of Illinois at Chicago, IL 60612, USA.

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http://dx.doi.org/10.1161/01.RES.0000173849.68636.1eDOI Listing
July 2005

A non-equilibrium isoelectric focusing method to determine states of phosphorylation of cardiac troponin I: identification of Ser-23 and Ser-24 as significant sites of phosphorylation by protein kinase C.

J Mol Cell Cardiol 2005 Jan 9;38(1):213-8. Epub 2004 Dec 9.

Department of Physiology and Biophysics, Center for Cardiovascular Research, College of Medicine, University of Illinois at Chicago, 835 S. Wolcott Avenue (M/C 901), Chicago, IL 60612, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002228280400317
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http://dx.doi.org/10.1016/j.yjmcc.2004.10.014DOI Listing
January 2005

Protein kinase Cepsilon overexpression alters myofilament properties and composition during the progression of heart failure.

Circ Res 2004 Aug 8;95(4):424-32. Epub 2004 Jul 8.

Section of Cardiology, University of Illinois at Chicago, 840 S Wood St, M/C 715, Chicago, IL 60612, USA.

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http://dx.doi.org/10.1161/01.RES.0000138299.85648.92DOI Listing
August 2004