Lorenz C Hofbauer

Lorenz C Hofbauer

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Lorenz C Hofbauer

Lorenz C Hofbauer

Publications by authors named "Lorenz C Hofbauer"

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Serum Profile of microRNAs Linked to Bone Metabolism During Sequential Treatment for Postmenopausal Osteoporosis.

J Clin Endocrinol Metab 2020 Aug;105(8)

Department of Medicine III, Technische Universität Dresden Medical Centre, Dresden, Germany.

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http://dx.doi.org/10.1210/clinem/dgaa368DOI Listing
August 2020

Evolving functions of Dickkopf-1 in cancer and immunity.

Cancer Lett 2020 Jul 3;482:1-7. Epub 2020 Apr 3.

Division of Endocrinology and Metabolic Bone Diseases, Department of Medicine III, Technische Universität Dresden, Dresden, Germany; Center for Healthy Ageing, Department of Medicine III, Technische Universität Dresden, Dresden, Germany; German Cancer Consortium (DKTK), Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2020.03.031DOI Listing
July 2020

Thyroid Hormone Actions and Bone Remodeling - The Role of the Wnt Signaling Pathway.

Exp Clin Endocrinol Diabetes 2020 Jun 20;128(6-07):450-454. Epub 2020 Jan 20.

Department of Medicine III and Center for Healthy Aging, Technische Universität Dresden, Germany.

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http://dx.doi.org/10.1055/a-1088-1215DOI Listing
June 2020

[Osteoporosis in the geriatric population].

Dtsch Med Wochenschr 2020 Jun 3;145(11):728-732. Epub 2020 Jun 3.

Bereich Endokrinologie/Diabetes/Metabolische Knochenerkrankungen, Medizinische Klinik III & UniversitätsCentrum für Gesundes Altern (UCGA), Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden.

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http://dx.doi.org/10.1055/a-1036-2701DOI Listing
June 2020

Author Correction: Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo.

Sci Rep 2020 Jun 4;10(1):9344. Epub 2020 Jun 4.

Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine III, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.1038/s41598-020-65962-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271193PMC
June 2020

Contributions of Dickkopf-1 to Obesity-Induced Bone Loss and Marrow Adiposity.

JBMR Plus 2020 Jun 28;4(6):e10364. Epub 2020 Apr 28.

Department of Medicine III, Center for Healthy Aging Technische Universität Dresden Dresden Germany.

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http://dx.doi.org/10.1002/jbm4.10364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285751PMC
June 2020

Denosumab in postmenopausal women with osteoporosis and diabetes: Subgroup analysis of FREEDOM and FREEDOM extension.

Bone 2020 May 10;134:115268. Epub 2020 Feb 10.

School of Medicine, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.bone.2020.115268DOI Listing
May 2020

Leopard skin.

Lancet Diabetes Endocrinol 2020 05 17;8(5):456. Epub 2020 Mar 17.

Center for Regenerative Therapies Dresden, Technische Universität Dresden, Dresden, Germany; Department of Medicine III, Technische Universität Dresden, Dresden, Germany; University Center for Healthy Aging, Technische Universität Dresden, Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(20)30076-0DOI Listing
May 2020

Disruption of the hepcidin/ferroportin regulatory circuitry causes low axial bone mass in mice.

Bone 2020 May 4;137:115400. Epub 2020 May 4.

Department of Medicine III, Technische Universität Dresden, Dresden, Germany; Center for Healthy Aging, Technische Universität Dresden, Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2020.115400DOI Listing
May 2020

Disruption of BMP Signaling Prevents Hyperthyroidism-Induced Bone Loss in Male Mice.

J Bone Miner Res 2020 May 26. Epub 2020 May 26.

Department of Medicine III, Universitätsklinikum Dresden, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.1002/jbmr.4092DOI Listing
May 2020

Dorsomorphin: A novel inhibitor of Dickkopf-1 in breast cancer.

Biochem Biophys Res Commun 2020 Apr 27;524(2):360-365. Epub 2020 Jan 27.

Division of Endocrinology and Metabolic Bone Diseases, Department of Medicine III, Technische Universität Dresden, Dresden, Germany; Center for Healthy Ageing Department of Medicine III, Technische Universität Dresden, Dresden, Germany; German Cancer Consortium (DKTK), Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2020.01.106DOI Listing
April 2020

Cholesterol and beyond - The role of the mevalonate pathway in cancer biology.

Biochim Biophys Acta Rev Cancer 2020 04 30;1873(2):188351. Epub 2020 Jan 30.

Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine III, Technische Universität Dresden, Germany; German Cancer Consortium (DKTK), partner site Dresden and German Cancer Research Center (DKFZ), Heidelberg, Germany; Center for Healthy Aging, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.1016/j.bbcan.2020.188351DOI Listing
April 2020

High serum levels of periostin are associated with a poor survival in breast cancer.

Breast Cancer Res Treat 2020 Apr 10;180(2):515-524. Epub 2020 Feb 10.

Department of Gynecology and Obstetrics, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1007/s10549-020-05570-0DOI Listing
April 2020

Lack of the Thyroid Hormone Transporter Mct8 in Osteoblast and Osteoclast Progenitors Increases Trabecular Bone in Male Mice.

Thyroid 2020 Feb 31;30(2):329-342. Epub 2020 Jan 31.

Department of Medicine III, Universitätsklinikum Dresden, Dresden, Germany.

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http://dx.doi.org/10.1089/thy.2019.0271DOI Listing
February 2020

Loss of Dkk-1 in Osteocytes Mitigates Alveolar Bone Loss in Mice With Periodontitis.

Front Immunol 2019 10;10:2924. Epub 2019 Dec 10.

Division of Endocrinology, Diabetes and Bone Diseases, Department of Medicine III & Center for Healthy Aging, Technical University, Dresden, Germany.

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http://dx.doi.org/10.3389/fimmu.2019.02924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914827PMC
December 2019

Effects of rigosertib on the osteo-hematopoietic niche in myelodysplastic syndromes.

Ann Hematol 2019 Sep 16;98(9):2063-2072. Epub 2019 Jul 16.

Medical Clinic and Policlinic 1, Hematology and Cellular Therapy, Leipzig University Hospital, Liebigstraße 22, 04103, Leipzig, Germany.

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http://dx.doi.org/10.1007/s00277-019-03756-1DOI Listing
September 2019

Osteogenic Dkk1 Mediates Glucocorticoid-Induced but Not Arthritis-Induced Bone Loss.

J Bone Miner Res 2019 07 7;34(7):1314-1323. Epub 2019 Mar 7.

Department of Medicine III, Technische Universität Dresden, Dresden, Germany.

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http://doi.wiley.com/10.1002/jbmr.3702
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http://dx.doi.org/10.1002/jbmr.3702DOI Listing
July 2019

Plasma levels of Semaphorin 4D are decreased by adjuvant tamoxifen but not aromatase inhibitor therapy in breast cancer patients.

J Bone Oncol 2019 Jun 4;16:100237. Epub 2019 Apr 4.

Division of Endocrinology, Diabetes and Bone Diseases, Department of Medicine III, TU Dresden Medical Center, Fetscherstraße 74, D-01307 Dresden, Germany.

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http://dx.doi.org/10.1016/j.jbo.2019.100237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461588PMC
June 2019

A Novel Strategy for Repairing Multiple Myeloma Bone Lesions: Lessons From Murine Models.

J Bone Miner Res 2019 05 9;34(5):781-782. Epub 2019 May 9.

Division of Endocrinology, Diabetes and Bone Diseases, Department of Medicine III & Center for Healthy Aging, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.1002/jbmr.3723DOI Listing
May 2019

The Role of Dickkopf-1 in Thyroid Hormone-Induced Changes of Bone Remodeling in Male Mice.

Endocrinology 2019 03;160(3):664-674

Department of Medicine III, Technische Universität Dresden Medical Center, Dresden, Germany.

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http://dx.doi.org/10.1210/en.2018-00998DOI Listing
March 2019

Update on the impact of type 2 diabetes mellitus on bone metabolism and material properties.

Endocr Connect 2019 Mar;8(3):R55-R70

Department of Medicine III & Center for Healthy Aging, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.1530/EC-18-0456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391903PMC
March 2019

Novel therapies in osteoporosis: PTH-related peptide analogs and inhibitors of sclerostin.

J Mol Endocrinol 2019 02;62(2):R145-R154

Department of Medicine III, Technische Universität Dresden Medical Center, Dresden, Germany.

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https://jme.bioscientifica.com/view/journals/jme/62/2/JME-18
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http://dx.doi.org/10.1530/JME-18-0173DOI Listing
February 2019

Prognostic Value of RANKL/OPG Serum Levels and Disseminated Tumor Cells in Nonmetastatic Breast Cancer.

Clin Cancer Res 2019 02 13;25(4):1369-1378. Epub 2018 Nov 13.

Department of Gynecology and Obstetrics, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-2482DOI Listing
February 2019

Induction of 3-hydroxy-3-methylglutaryl-CoA reductase mediates statin resistance in breast cancer cells.

Cell Death Dis 2019 01 28;10(2):91. Epub 2019 Jan 28.

Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine III, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.1038/s41419-019-1322-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349912PMC
January 2019

Bone health during endocrine therapy for cancer.

Lancet Diabetes Endocrinol 2018 11 20;6(11):901-910. Epub 2018 Mar 20.

Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine III, and Center for Healthy Aging, Technische Universität Dresden, Dresden, Germany; German Cancer Consortium (DKTK), partner site Dresden, and German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22138587183004
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http://dx.doi.org/10.1016/S2213-8587(18)30047-0DOI Listing
November 2018

Differential effects of high-fat diet and exercise training on bone and energy metabolism.

Bone 2018 11 20;116:120-134. Epub 2018 Jul 20.

Division of Endocrinology, Diabetes, and Metabolic Bone Diseases, Department of Medicine III, Technische Universität Dresden, Germany; Center for Healthy Aging, Technische Universität Dresden, Germany; Center for Regenerative Therapies Dresden, Technische Universität Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2018.07.015DOI Listing
November 2018

β-Blockers and bone health.

J Clin Invest 2018 11 2;128(11):4745-4747. Epub 2018 Oct 2.

Department of Medicine III.

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http://dx.doi.org/10.1172/JCI122992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205370PMC
November 2018

Postnatal Skeletal Deletion of Dickkopf-1 Increases Bone Formation and Bone Volume in Male and Female Mice, Despite Increased Sclerostin Expression.

J Bone Miner Res 2018 09 12;33(9):1698-1707. Epub 2018 Jun 12.

Department of Medicine III, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.1002/jbmr.3463DOI Listing
September 2018

Denosumab: a new treatment option for glucocorticoid-induced osteoporosis.

Lancet Diabetes Endocrinol 2018 06 6;6(6):428-429. Epub 2018 Apr 6.

Department of Medicine III, and Center for Healthy Aging, Technische Universität Dresden Medical Center, Fetscherstraße 74, 01307 Dresden, Germany; Center for Regenerative Therapies Dresden, Dresden, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22138587183009
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http://dx.doi.org/10.1016/S2213-8587(18)30097-4DOI Listing
June 2018

Associations of myeloid hematological diseases of the elderly with osteoporosis: A longitudinal analysis of routine health care data.

Leuk Res 2018 06 21;69:81-86. Epub 2018 Apr 21.

TU Dresden, Medizinische Fakultät Carl Gustav Carus, Center for Evidence-Based Healthcare, Dresden, Germany; National Center for Tumor Diseases, Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.leukres.2018.04.010DOI Listing
June 2018

Selective inhibition of receptor activator of NF-κB ligand (RANKL) in hematopoietic cells improves outcome after experimental myocardial infarction.

J Mol Med (Berl) 2018 06 8;96(6):559-573. Epub 2018 May 8.

Institute of Physiology, Pathophysiology and Biophysics, Department of Biomedical Research, University of Veterinary Medicine Vienna, Veterinaerplatz 1, 1210, Vienna, Austria.

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http://dx.doi.org/10.1007/s00109-018-1641-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988763PMC
June 2018

Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo.

Sci Rep 2018 06 7;8(1):8711. Epub 2018 Jun 7.

Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine III, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.1038/s41598-018-26300-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992207PMC
June 2018

Apalutamide and Metastasis-free Survival in Prostate Cancer.

N Engl J Med 2018 06;378(26):2541-2

Technische Universität Dresden, Dresden, Germany

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http://dx.doi.org/10.1056/NEJMc1806189DOI Listing
June 2018

Immunoadsorption Followed by Rituximab as a Definitive Treatment for Insulin Autoimmune Syndrome (Hirata Syndrome): A Case Report.

Diabetes Care 2018 Mar 27;41(3):e23-e24. Epub 2017 Dec 27.

Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine III, and Center for Healthy Aging, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany

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http://care.diabetesjournals.org/lookup/doi/10.2337/dc17-197
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http://dx.doi.org/10.2337/dc17-1974DOI Listing
March 2018

Romosozumab versus Alendronate and Fracture Risk in Women with Osteoporosis.

N Engl J Med 2018 01;378(2):195

Technische Universität Dresden, Dresden, Germany

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http://dx.doi.org/10.1056/NEJMc1714810DOI Listing
January 2018

Immune Suppressive and Bone Inhibitory Effects of Prednisolone in Growing and Regenerating Zebrafish Tissues.

J Bone Miner Res 2017 Dec 13;32(12):2476-2488. Epub 2017 Sep 13.

Center for Regenerative Therapies Dresden (CRTD) and Biotechnology Center, Technische Universität Dresden, Dresden, Germany.

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http://doi.wiley.com/10.1002/jbmr.3231
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http://dx.doi.org/10.1002/jbmr.3231DOI Listing
December 2017

Alterations within the Osteo-Hematopoietic Niche in MDS and their Therapeutic Implications.

Curr Pharm Des 2016 ;22(16):2323-32

Department of Medicine I, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden, Fetscherstr. 74, 01307 Dresden, Germany.

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http://dx.doi.org/10.2174/1381612822666160226132914DOI Listing
November 2017

Prediction of Fractures and Major Cardiovascular Events in Men Using Serum Osteoprotegerin Levels: The Prospective STRAMBO Study.

J Bone Miner Res 2017 Nov 7;32(11):2288-2296. Epub 2017 Aug 7.

Division of Endocrinology, Diabetes, and Bone Diseases, TU Dresden Medical Center, Dresden, Germany.

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http://dx.doi.org/10.1002/jbmr.3213DOI Listing
November 2017

Osteoporosis treatment: recent developments and ongoing challenges.

Lancet Diabetes Endocrinol 2017 11 7;5(11):898-907. Epub 2017 Jul 7.

Division of Endocrinology, Diabetes, and Bone Diseases, Carl Gustav Carus University Hospital, Dresden Technical University, Dresden, Germany; Centre for Healthy Aging, Carl Gustav Carus University Hospital, Dresden Technical University, Dresden, Germany.

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http://dx.doi.org/10.1016/S2213-8587(17)30188-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798872PMC
November 2017

Sclerostin Blockade and Zoledronic Acid Improve Bone Mass and Strength in Male Mice With Exogenous Hyperthyroidism.

Endocrinology 2017 11;158(11):3765-3777

Department of Medicine III, Technische Universität Dresden Medical Center, 01307 Dresden, Germany.

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http://dx.doi.org/10.1210/en.2017-00247DOI Listing
November 2017

Bone Mass Is Compromised by the Chemotherapeutic Trabectedin in Association With Effects on Osteoblasts and Macrophage Efferocytosis.

J Bone Miner Res 2017 Oct 31;32(10):2116-2127. Epub 2017 Aug 31.

Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1002/jbmr.3196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640484PMC
October 2017

Adjuvant tamoxifen but not aromatase inhibitor therapy decreases serum levels of the Wnt inhibitor dickkopf-1 while not affecting sclerostin in breast cancer patients.

Breast Cancer Res Treat 2017 Aug 19;164(3):737-743. Epub 2017 May 19.

Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine III, TU Dresden Medical Center, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.

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http://dx.doi.org/10.1007/s10549-017-4296-3DOI Listing
August 2017

Concurrent antitumor and bone-protective effects of everolimus in osteotropic breast cancer.

Breast Cancer Res 2017 Aug 9;19(1):92. Epub 2017 Aug 9.

Division of Endocrinology, Diabetes and Bone Diseases, Department of Medicine III, Technical University Dresden, Fetscherstraße 74, D-01307, Dresden, Germany.

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http://dx.doi.org/10.1186/s13058-017-0885-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5551016PMC
August 2017

Microdialysis Sampling from Wound Fluids Enables Quantitative Assessment of Cytokines, Proteins, and Metabolites Reveals Bone Defect-Specific Molecular Profiles.

PLoS One 2016 21;11(7):e0159580. Epub 2016 Jul 21.

University Center of Orthopedics and Trauma Surgery and Center for Translational Bone, Joint and Soft Tissue Research, University Hospital "Carl Gustav Carus", TU Dresden, Dresden, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0159580PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4956113PMC
July 2017

[New Osteoanabolic Therapies for Osteoporosis].

Dtsch Med Wochenschr 2017 Apr 7;142(7):475-478. Epub 2017 Apr 7.

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http://dx.doi.org/10.1055/s-0042-122721DOI Listing
April 2017

Wnt5a is a key target for the pro-osteogenic effects of iron chelation on osteoblast progenitors.

Haematologica 2016 12 18;101(12):1499-1507. Epub 2016 Aug 18.

Department of Medicine III, Technische Universität Dresden, Saxony, Germany

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http://dx.doi.org/10.3324/haematol.2016.144808DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479606PMC
December 2016

Bone Formation and the Wnt Signaling Pathway.

N Engl J Med 2016 11;375(19):1902

TU Dresden Medical Center, Dresden, Germany

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http://dx.doi.org/10.1056/NEJMc1609768DOI Listing
November 2016

Increased EPO Levels Are Associated With Bone Loss in Mice Lacking PHD2 in EPO-Producing Cells.

J Bone Miner Res 2016 10 13;31(10):1877-1887. Epub 2016 May 13.

Department of Clinical Pathobiochemistry, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.1002/jbmr.2857DOI Listing
October 2016

Sclerostin Blockade-A Dual Mode of Action After All?

J Bone Miner Res 2016 10 14;31(10):1787-1790. Epub 2016 Sep 14.

Department of Medicine 3, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.1002/jbmr.2988DOI Listing
October 2016

Romosozumab Treatment in Postmenopausal Women with Osteoporosis.

N Engl J Med 2016 10 18;375(16):1532-1543. Epub 2016 Sep 18.

From Helen Hayes Hospital, West Haverstraw, and Columbia University, New York (F.C.) - both in New York; Amgen, Thousand Oaks, CA (D.B.C., C.E.M., L.C., J.M., A.G.); McMaster University, Hamilton, ON, Canada (J.D.A.); University of Wisconsin-Madison Osteoporosis Clinical Center and Research Program, Madison (N.B.); Krakow Medical Center, Krakow, Poland (E.C.); Geneva University Hospital, Geneva (S.F.); the Division of Endocrinology, Diabetes, and Bone Diseases, Center for Healthy Aging, Technische Universität Dresden Medical Center, Dresden, Germany (L.C.H.); the Center for Clinical and Basic Research, Hong Kong (E.L.); New Mexico Clinical Research and Osteoporosis Center, Albuquerque (E.M.L.); Miyauchi Medical Center, Osaka, Japan (A.M.); Centro Paulista de Investigação Clinica, São Paulo (C.A.F.Z.); and UCB Pharma, Brussels (P.D.M., C.L.).

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http://dx.doi.org/10.1056/NEJMoa1607948DOI Listing
October 2016

Postmenopausal osteoporosis.

Nat Rev Dis Primers 2016 09 29;2:16069. Epub 2016 Sep 29.

San Francisco Coordinating Center, California Pacific Medical Center Research Institute and the University of California, San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1038/nrdp.2016.69DOI Listing
September 2016

Functional Interference in the Bone Marrow Microenvironment by Disseminated Breast Cancer Cells.

Stem Cells 2016 08 18;34(8):2224-35. Epub 2016 May 18.

Department of Hematology/Oncology, Medical Clinic and Policlinic I, University Hospital, Dresden, Germany.

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http://doi.wiley.com/10.1002/stem.2384
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http://dx.doi.org/10.1002/stem.2384DOI Listing
August 2016

WNT5A and Its Receptors in the Bone-Cancer Dialogue.

J Bone Miner Res 2016 08;31(8):1488-96

Division of Endocrinology and Metabolic Bone Diseases, Department of Medicine III, Technische Universität (TU) Dresden Medical Center, Dresden, Germany.

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http://dx.doi.org/10.1002/jbmr.2899DOI Listing
August 2016

Role of milk fat globule-epidermal growth factor 8 in osteoimmunology.

Bonekey Rep 2016 20;5:820. Epub 2016 Jul 20.

Department of Medicine III, Division of Endocrinology, Diabetes, and Bone Diseases, Technische Universität Dresden , Dresden, Germany.

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http://dx.doi.org/10.1038/bonekey.2016.52DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4954605PMC
August 2016

Sulfated hyaluronan improves bone regeneration of diabetic rats by binding sclerostin and enhancing osteoblast function.

Biomaterials 2016 07 21;96:11-23. Epub 2016 Apr 21.

Division of Endocrinology, Diabetes, and Metabolic Bone Diseases, Department of Medicine III, TU Dresden Medical Center, Dresden, Germany; Center for Regenerative Therapies Dresden, Dresden, Germany; Center for Healthy Aging, TU Dresden Medical Center, Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2016.04.013DOI Listing
July 2016

Skeletal Metabolism, Fracture Risk, and Fracture Outcomes in Type 1 and Type 2 Diabetes.

Diabetes 2016 07;65(7):1757-66

Department of Epidemiology & Biostatistics, University of California, San Francisco, San Francisco, CA.

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http://dx.doi.org/10.2337/db16-0063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915586PMC
July 2016

Combined inhibition of the mevalonate pathway with statins and zoledronic acid potentiates their anti-tumor effects in human breast cancer cells.

Cancer Lett 2016 May 8;375(1):162-171. Epub 2016 Mar 8.

Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine III, Technische Universität Dresden, Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2016.03.004DOI Listing
May 2016

Sweet and brittle - Diabetes mellitus and the skeleton.

Bone 2016 Jan 9;82. Epub 2015 Sep 9.

Bone Research Program, ANZAC Research Institute, and Department of Endcorinology, Concord Hospital, The University Sydney, Sydney, Australia.

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http://dx.doi.org/10.1016/j.bone.2015.09.001DOI Listing
January 2016

Potentiated suppression of Dickkopf-1 in breast cancer by combined administration of the mevalonate pathway inhibitors zoledronic acid and statins.

Breast Cancer Res Treat 2015 Dec 29;154(3):623-31. Epub 2015 Oct 29.

Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine III, Technische Universität Dresden, Fetscherstraße 74, 01307, Dresden, Germany.

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http://dx.doi.org/10.1007/s10549-015-3624-8DOI Listing
December 2015

Serum fetuin-A levels and abdominal aortic calcification in healthy men - The STRAMBO study.

Bone 2015 Oct 12;79:196-202. Epub 2015 Jun 12.

INSERM UMR 1033, University of Lyon, Hospices Civils de Lyon, F-69437 Lyon, France. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2015.06.004DOI Listing
October 2015

Hyperthyroidism and Hypothyroidism in Male Mice and Their Effects on Bone Mass, Bone Turnover, and the Wnt Inhibitors Sclerostin and Dickkopf-1.

Endocrinology 2015 Oct 28;156(10):3517-27. Epub 2015 Jul 28.

Department of Medicine III (E.T., L.C.H., M.R.), Technische Universität Dresden Medical Center, and Center for Regenerative Therapies (L.C.H.), 01307 Dresden, Germany; and Institut für Experimentelle Endokrinologie (E.R., J.K.), Charité Universitätsmedizin, 10117 Berlin, Germany.

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http://dx.doi.org/10.1210/en.2015-1073DOI Listing
October 2015

Structural and functional insights into sclerostin-glycosaminoglycan interactions in bone.

Biomaterials 2015 Oct 15;67:335-45. Epub 2015 Jul 15.

Division of Endocrinology, Diabetes and Bone Diseases, Department of Medicine III, Technische Universität Dresden, Medical Center, D-01307 Dresden, Germany; Center for Regenerative Therapies Dresden, D-01307 Dresden, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2015.07.021DOI Listing
October 2015

P38 regulates the Wnt inhibitor Dickkopf-1 in breast cancer.

Biochem Biophys Res Commun 2015 Oct 25;466(4):728-32. Epub 2015 Sep 25.

Division of Endocrinology and Metabolic Bone Diseases, Department of Medicine III, Technische Universität Dresden, Dresden, Germany; DFG Research Center and Cluster of Excellence for Regenerative Therapies, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2015.09.101DOI Listing
October 2015

Bioinspired Collagen/Glycosaminoglycan-Based Cellular Microenvironments for Tuning Osteoclastogenesis.

ACS Appl Mater Interfaces 2015 Oct 19;7(42):23787-97. Epub 2015 Oct 19.

Institute of Materials Science, Max Bergmann Center of Biomaterials, Technische Universität Dresden , Budapester Straße 27, 01069 Dresden, Germany.

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http://dx.doi.org/10.1021/acsami.5b08419DOI Listing
October 2015

More DATA to guide sequential osteoporosis therapy.

Lancet 2015 Sep 2;386(9999):1116-8. Epub 2015 Jul 2.

Division of Endocrinology, Diabetes, and Bone Diseases, Technische Universität Dresden Medical Center, 01307 Dresden, Germany.

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http://dx.doi.org/10.1016/S0140-6736(15)61175-8DOI Listing
September 2015

Cancer-targeted therapies and radiopharmaceuticals.

Bonekey Rep 2015 3;4:707. Epub 2015 Jun 3.

Division of Endocrinology, Diabetes and Bone Diseases, Department of Medicine III, Dresden University Medical Center , Dresden, Germany ; Center for Regenerative Therapies, Dresden Technical University , Dresden, Germany.

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http://dx.doi.org/10.1038/bonekey.2015.76DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4455688PMC
July 2015

Are there still east-to-west differences in the incidence of hip fractures in Germany?

Arch Osteoporos 2014 17;9:195. Epub 2014 Oct 17.

Medical Office, Großenhainer Strasse 129, 01129, Dresden, Germany,

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http://dx.doi.org/10.1007/s11657-014-0195-yDOI Listing
May 2015

WNT5A has anti-prostate cancer effects in vitro and reduces tumor growth in the skeleton in vivo.

J Bone Miner Res 2015 Mar;30(3):471-80

Division of Endocrinology and Metabolic Bone Diseases, Department of Medicine III, Technische Universität Dresden, Dresden, Germany.

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http://dx.doi.org/10.1002/jbmr.2362DOI Listing
March 2015

Targeting bone metabolism in patients with advanced prostate cancer: current options and controversies.

Int J Endocrinol 2015 31;2015:838202. Epub 2015 Jan 31.

Department of Medicine III, Technische Universität Dresden Medical Center, Fetscherstraße 74, 01307 Dresden, Germany.

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http://dx.doi.org/10.1155/2015/838202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329828PMC
March 2015

Breast carcinoma cells modulate the chemoattractive activity of human bone marrow-derived mesenchymal stromal cells by interfering with CXCL12.

Int J Cancer 2015 Jan 20;136(1):44-54. Epub 2014 May 20.

Division of Hematology, Oncology and Stem Cell Transplantation, Department of Medicine I, University Hospital Carl Gustav Carus, Technische Universiät Dresden, Germany.

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http://dx.doi.org/10.1002/ijc.28960DOI Listing
January 2015

Associations between ambient air pollution and bone turnover markers in 10-year old children: results from the GINIplus and LISAplus studies.

Int J Hyg Environ Health 2015 Jan 2;218(1):58-65. Epub 2014 Aug 2.

Helmholtz Zentrum München, German Research Centre for Environmental Health, Institute of Epidemiology I, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ijheh.2014.07.006DOI Listing
January 2015

Probenecid as a sensitizer of bisphosphonate-mediated effects in breast cancer cells.

Mol Cancer 2014 Dec 11;13:265. Epub 2014 Dec 11.

Orthopedic Center for Musculoskeletal Research, University of Würzburg, Brettreichstrasse 11, 97074 Würzburg, Germany.

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http://dx.doi.org/10.1186/1476-4598-13-265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4295226PMC
December 2014

Advanced radioiodine-refractory differentiated thyroid cancer: the sodium iodide symporter and other emerging therapeutic targets.

Lancet Diabetes Endocrinol 2014 Oct 2;2(10):830-42. Epub 2014 Jun 2.

Division of Endocrinology and Metabolism, Mayo Clinic, Rochester, MN, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S22138587147005
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http://dx.doi.org/10.1016/S2213-8587(14)70051-8DOI Listing
October 2014

Effect of aromatase inhibition on serum levels of sclerostin and dickkopf-1, bone turnover markers and bone mineral density in women with breast cancer.

J Cancer Res Clin Oncol 2014 Oct 7;140(10):1671-80. Epub 2014 Jun 7.

Department of Gynecological Endocrinology, Reproductive Medicine and Osteoporosis, Philipps-University of Marburg, Baldingerstr. 1, 35041, Marburg, Germany,

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http://link.springer.com/content/pdf/10.1007/s00432-014-1726
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http://link.springer.com/10.1007/s00432-014-1726-z
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http://dx.doi.org/10.1007/s00432-014-1726-zDOI Listing
October 2014

Endocrine aspects of bone metastases.

Lancet Diabetes Endocrinol 2014 Jun 24;2(6):500-12. Epub 2014 Jan 24.

Orthopaedic Center for Musculoskeletal Research, Wuerzburg, Germany.

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http://dx.doi.org/10.1016/S2213-8587(13)70203-1DOI Listing
June 2014

An exotic cause of exudative enteropathy.

Am J Case Rep 2014 22;15:226-9. Epub 2014 May 22.

Department of Endocrinology, Diabetes and Bone Diseases, University Clinic Dresden, Dresden, Germany.

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http://dx.doi.org/10.12659/AJCR.890483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038641PMC
June 2014

Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1.

Nat Commun 2014 May 2;5:3793. Epub 2014 May 2.

Institute of Clinical Molecular Biology and Tumor Genetics, Helmholtz Zentrum München, National Research Center for Environmental Health, Marchioninistrasse 25, 81377 Munich, Germany.

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http://dx.doi.org/10.1038/ncomms4793DOI Listing
May 2014