Lorene K Langeberg

Lorene K Langeberg

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Lorene K Langeberg

Lorene K Langeberg

Publications by authors named "Lorene K Langeberg"

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AKAP220 manages apical actin networks that coordinate aquaporin-2 location and renal water reabsorption.

Proc Natl Acad Sci U S A 2016 07 11;113(30):E4328-37. Epub 2016 Jul 11.

Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195; Department of Pharmacology, University of Washington, Seattle, WA 98195

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http://dx.doi.org/10.1073/pnas.1607745113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968721PMC
July 2016

A mitotic kinase scaffold depleted in testicular seminomas impacts spindle orientation in germ line stem cells.

Elife 2015 Sep 25;4:e09384. Epub 2015 Sep 25.

Department of Pharmacology, Howard Hughes Medical Institute, University of Washington, Seattle, United States.

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http://dx.doi.org/10.7554/eLife.09384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4612572PMC
September 2015

Protein Kinase A Opposes the Phosphorylation-dependent Recruitment of Glycogen Synthase Kinase 3β to A-kinase Anchoring Protein 220.

J Biol Chem 2015 Aug 18;290(32):19445-57. Epub 2015 Jun 18.

From the Howard Hughes Medical Institute, Department of Pharmacology, University of Washington School of Medicine, Seattle, Washington 98195,

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http://dx.doi.org/10.1074/jbc.M115.654822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528109PMC
August 2015

Signalling scaffolds and local organization of cellular behaviour.

Nat Rev Mol Cell Biol 2015 Apr 18;16(4):232-44. Epub 2015 Mar 18.

Howard Hughes Medical Institute and Department of Pharmacology, University of Washington, 1959 NE Pacific Street, Seattle, Washington 98195, USA.

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http://www.nature.com/articles/nrm3966
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http://dx.doi.org/10.1038/nrm3966DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4722875PMC
April 2015

Intrinsic disorder within an AKAP-protein kinase A complex guides local substrate phosphorylation.

Elife 2013 Nov 5;2:e01319. Epub 2013 Nov 5.

Department of Pharmacology, Howard Hughes Medical Institute, University of Washington, Seattle, United States.

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http://dx.doi.org/10.7554/eLife.01319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814001PMC
November 2013

Gravin is a transitory effector of polo-like kinase 1 during cell division.

Mol Cell 2012 Nov 11;48(4):547-59. Epub 2012 Oct 11.

Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1016/j.molcel.2012.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513578PMC
November 2012

Anchored phosphatases modulate glucose homeostasis.

EMBO J 2012 Oct 31;31(20):3991-4004. Epub 2012 Aug 31.

Department of Pharmacology, Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1038/emboj.2012.244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474922PMC
October 2012

Coordinated signal integration at the M-type potassium channel upon muscarinic stimulation.

EMBO J 2012 May 29;31(14):3147-56. Epub 2012 May 29.

Department of Pharmacology, University of California, Irvine, CA 92697, USA.

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http://dx.doi.org/10.1038/emboj.2012.156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400014PMC
May 2012

AKAP2 anchors PKA with aquaporin-0 to support ocular lens transparency.

EMBO Mol Med 2012 Jan 16;4(1):15-26. Epub 2011 Nov 16.

Department of Pharmacology, Howard Hughes Medical Institute, University of Washington School of Medicine, Seattle, WA, USA.

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http://embomolmed.embopress.org/cgi/doi/10.1002/emmm.2011001
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http://dx.doi.org/10.1002/emmm.201100184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272850PMC
January 2012

AKAP220 protein organizes signaling elements that impact cell migration.

J Biol Chem 2011 Nov 2;286(45):39269-81. Epub 2011 Sep 2.

Howard Hughes Medical Institute, University of Washington School of Medicine, Seattle, Washington 98195, USA.

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http://dx.doi.org/10.1074/jbc.M111.277756DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234751PMC
November 2011

An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria.

Proc Natl Acad Sci U S A 2011 Nov 14;108(48):E1227-35. Epub 2011 Nov 14.

Department of Pharmacology, Howard Hughes Medical Institute, University of Washington School of Medicine, 1959 Pacific Avenue NE, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1073/pnas.1107182108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228425PMC
November 2011

Anchored protein kinase A recruitment of active Rac GTPase.

J Biol Chem 2011 Jun 1;286(25):22113-21. Epub 2011 Apr 1.

Howard Hughes Medical Institute, University of Washington School of Medicine, Seattle, Washington 98195, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M111.232660
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http://dx.doi.org/10.1074/jbc.M111.232660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121355PMC
June 2011

AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade.

Nat Cell Biol 2010 Dec 21;12(12):1242-9. Epub 2010 Nov 21.

Howard Hughes Medical Institute, Department of Pharmacology, University of Washington School of Medicine, 1959 Pacific Avenue NE, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1038/ncb2130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042953PMC
December 2010

Interaction with AKAP79 modifies the cellular pharmacology of PKC.

Mol Cell 2010 Feb;37(4):541-50

Department of Pharmacology, 360 Med Surge II, University of California, Irvine, Irvine, CA 92697, USA.

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http://dx.doi.org/10.1016/j.molcel.2010.01.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014287PMC
February 2010

mAKAP compartmentalizes oxygen-dependent control of HIF-1alpha.

Sci Signal 2008 Dec 23;1(51):ra18. Epub 2008 Dec 23.

1Howard Hughes Medical Institute and Vollum Institute, Oregon Health & Science University, 3181 S. W. Sam Jackson Park Road, Portland, OR 97239, USA.

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http://dx.doi.org/10.1126/scisignal.2000026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828263PMC
December 2008

AKAP-Lbc mobilizes a cardiac hypertrophy signaling pathway.

Mol Cell 2008 Oct;32(2):169-79

Howard Hughes Medical Institute, Vollum Institute, Oregon Health and Science University, Portland, OR 97239, USA.

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http://dx.doi.org/10.1016/j.molcel.2008.08.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169907PMC
October 2008

Loss of AKAP150 perturbs distinct neuronal processes in mice.

Proc Natl Acad Sci U S A 2008 Aug 18;105(34):12557-62. Epub 2008 Aug 18.

Howard Hughes Medical Institute, Oregon Health and Science University, 3181 South West Sam Jackson Park Road, Portland, Oregon 97239, USA.

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http://dx.doi.org/10.1073/pnas.0805922105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527950PMC
August 2008

MyRIP anchors protein kinase A to the exocyst complex.

J Biol Chem 2007 Nov 7;282(45):33155-67. Epub 2007 Sep 7.

Howard Hughes Medical Institute, Vollum Institute, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.

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http://dx.doi.org/10.1074/jbc.M705167200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508720PMC
November 2007

Dynamic regulation of cAMP synthesis through anchored PKA-adenylyl cyclase V/VI complexes.

Mol Cell 2006 Sep;23(6):925-31

Howard Hughes Medical Institute, Vollum Institute, L-474, Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Portland, Oregon 97239, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S109727650600526
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http://dx.doi.org/10.1016/j.molcel.2006.07.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941446PMC
September 2006

AKAP signaling complexes: getting to the heart of the matter.

Trends Mol Med 2006 Jul 30;12(7):317-23. Epub 2006 Jun 30.

Howard Hughes Medical Institute, Vollum Institute, L-474, Oregon Health & Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR 97239, USA.

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http://dx.doi.org/10.1016/j.molmed.2006.05.008DOI Listing
July 2006

The where's and when's of kinase anchoring.

Trends Biochem Sci 2006 Jun 11;31(6):316-23. Epub 2006 May 11.

Howard Hughes Medical Institute, Vollum Institute, Oregon Health and Sciences University, MRB322, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.

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http://dx.doi.org/10.1016/j.tibs.2006.04.009DOI Listing
June 2006

Distinct enzyme combinations in AKAP signalling complexes permit functional diversity.

Nat Cell Biol 2005 Nov;7(11):1066-73

Howard Hughes Medical Institute, Vollum Institute, Oregon Health and Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR 97239, USA.

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http://dx.doi.org/10.1038/ncb1315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3923410PMC
November 2005

A-kinase-anchoring proteins.

J Cell Sci 2005 Aug;118(Pt 15):3217-20

Howard Hughes Medical Institute, Vollum Institute, Oregon Health and Sciences University, Portland, OR 97239, USA.

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http://dx.doi.org/10.1242/jcs.02416DOI Listing
August 2005

AKAP-Lbc nucleates a protein kinase D activation scaffold.

Mol Cell 2004 Sep;15(6):889-99

Howard Hughes Medical Institute, Vollum Institute, Oregon Health and Sciences University, Portland, OR 97239, USA.

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http://dx.doi.org/10.1016/j.molcel.2004.09.015DOI Listing
September 2004

PKA-phosphorylation of PDE4D3 facilitates recruitment of the mAKAP signalling complex.

Biochem J 2004 Aug;381(Pt 3):587-92

Howard Hughes Medical Institute and Vollum Institute, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239-3098, USA.

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http://dx.doi.org/10.1042/BJ20040846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1133866PMC
August 2004

Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression.

Neuron 2003 Oct;40(3):595-607

Howard Hughes Medical Institute, Vollum Institute, Oregon Health and Science University, Portland, OR 97239, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963808PMC
October 2003

AKAP150 signaling complex promotes suppression of the M-current by muscarinic agonists.

Nat Neurosci 2003 Jun;6(6):564-71

Department of Biophysical Genetics, Kanazawa University Graduate School of Medicine, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640, Japan.

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http://dx.doi.org/10.1038/nn1062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941299PMC
June 2003

Bioinformatic design of A-kinase anchoring protein-in silico: a potent and selective peptide antagonist of type II protein kinase A anchoring.

Proc Natl Acad Sci U S A 2003 Apr 2;100(8):4445-50. Epub 2003 Apr 2.

Howard Hughes Medical Institute, Vollum Institute, Oregon Health and Science University, Portland OR 97239, USA.

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http://www.pnas.org/cgi/doi/10.1073/pnas.0330734100
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http://dx.doi.org/10.1073/pnas.0330734100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC153575PMC
April 2003

Loss of WAVE-1 causes sensorimotor retardation and reduced learning and memory in mice.

Proc Natl Acad Sci U S A 2003 Feb 10;100(4):1723-8. Epub 2003 Feb 10.

Howard Hughes Medical Institute, Vollum Institute, Oregon Health and Science University, Portland, OR 97239, USA.

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http://dx.doi.org/10.1073/pnas.0438033100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC149900PMC
February 2003

Intracellular targeting of protein kinases and phosphatases.

Diabetes 2002 Dec;51 Suppl 3:S385-8

Howard Hughes Medical Institute, Vollum Institute, Portland, Oregon 97201-3098, USA.

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December 2002

Regulation of GluR1 by the A-kinase anchoring protein 79 (AKAP79) signaling complex shares properties with long-term depression.

J Neurosci 2002 Apr;22(8):3044-51

Howard Hughes Medical Institute, Vollum Institute, Oregon Health Sciences University, Portland, Oregon 97201, USA.

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http://dx.doi.org/20026277DOI Listing
April 2002