Lorena Lorefice

Lorena Lorefice

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Lorena Lorefice

Lorena Lorefice

Publications by authors named "Lorena Lorefice"

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Assessing the Metabolomic Profile of Multiple Sclerosis Patients Treated with Interferon Beta 1a by H-NMR Spectroscopy.

Neurotherapeutics 2019 07;16(3):797-807

Multiple Sclerosis Centre, Department of Medical Sciences and Public Health, Binaghi Hospital, University of Cagliari, via Is Guadazzonis 2, 09126, Cagliari, Italy.

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http://dx.doi.org/10.1007/s13311-019-00721-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694336PMC
July 2019

Efficacy and safety of alemtuzumab in a real-life cohort of patients with multiple sclerosis.

J Neurol 2019 Jun 12;266(6):1405-1411. Epub 2019 Mar 12.

Multiple Sclerosis Center, University of Cagliari/ATS Sardegna, Via Is Guadazzonis, 2, 09126, Cagliari, Italy.

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http://dx.doi.org/10.1007/s00415-019-09272-6DOI Listing
June 2019

Multiple sclerosis and HLA genotypes: A possible influence on brain atrophy.

Mult Scler 2019 01 7;25(1):23-30. Epub 2017 Nov 7.

Multiple Sclerosis Center, Binaghi Hospital, ATS Sardegna, Cagliari, Italy/Department of Medical Science and Public Health, University of Cagliari, Cagliari, Italy.

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http://dx.doi.org/10.1177/1352458517739989DOI Listing
January 2019

The impact of visible and invisible symptoms on employment status, work and social functioning in Multiple Sclerosis.

Work 2018 ;60(2):263-270

Department of Medical Sciences and Public Health, Multiple Sclerosis Centre, University of Cagliari, Sardinia, Italy.

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http://dx.doi.org/10.3233/WOR-182682DOI Listing
January 2019

Association between brain atrophy and cognitive motor interference in multiple sclerosis.

Mult Scler Relat Disord 2018 Oct 31;25:208-211. Epub 2018 Jul 31.

Multiple Sclerosis Center, Department of Medical Science and Public Health, University of Cagliari, Via Is Guadazzonis 2, Cagliari 09126, Italy.

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http://dx.doi.org/10.1016/j.msard.2018.07.045DOI Listing
October 2018

Top-down proteomic profiling of human saliva in multiple sclerosis patients.

J Proteomics 2018 09 4;187:212-222. Epub 2018 Aug 4.

Department of Life and Environmental Sciences, Biomedical Section, University of Cagliari, Monserrato Campus, 09042 Monserrato, Cagliari, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S18743919183030
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http://dx.doi.org/10.1016/j.jprot.2018.07.019DOI Listing
September 2018

Does focal inflammation have an impact on cognition in multiple sclerosis? An MRI study.

Mult Scler Relat Disord 2018 Jul 16;23:83-87. Epub 2018 May 16.

Multiple Sclerosis Centre, Binaghi Hospital, Department of medical sciences and public health, University of Cagliari, Cagliari, 09126, Italy.

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http://dx.doi.org/10.1016/j.msard.2018.05.012DOI Listing
July 2018

Exploring cognitive motor interference in multiple sclerosis by the visual Stroop test.

Mult Scler Relat Disord 2018 May 24;22:8-11. Epub 2018 Feb 24.

Department of Mechanical, Chemical and Materials Engineering, University of Cagliari, Cagliari, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2018.02.026DOI Listing
May 2018

Autoimmune comorbidities in multiple sclerosis: what is the influence on brain volumes? A case-control MRI study.

J Neurol 2018 May 5;265(5):1096-1101. Epub 2018 Mar 5.

Department of Medical Sciences and Public Health, Multiple Sclerosis Center, Binaghi Hospital, ATS Sardegna, University of Cagliari, via Is Guadazzonis 2, 09126, Cagliari, Italy.

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http://dx.doi.org/10.1007/s00415-018-8811-1DOI Listing
May 2018

A cross-sectional and longitudinal study evaluating brain volumes, RNFL, and cognitive functions in MS patients and healthy controls.

BMC Neurol 2018 May 11;18(1):67. Epub 2018 May 11.

Multiple Sclerosis Center Binaghi Hospital, Department of Medical Sciences and Public Health, University of Cagliari, via Is Guadazzonis 2, 09126, Cagliari, Italy.

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http://dx.doi.org/10.1186/s12883-018-1065-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5946463PMC
May 2018

New horizons for multiple sclerosis therapeutics: milestones in the development of ocrelizumab.

Neuropsychiatr Dis Treat 2018 23;14:1093-1099. Epub 2018 Apr 23.

Multiple Sclerosis Center Binaghi Hospital, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.

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http://dx.doi.org/10.2147/NDT.S147874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922247PMC
April 2018

The burden of multiple sclerosis and patients' coping strategies.

BMJ Support Palliat Care 2018 Mar 24;8(1):38-40. Epub 2017 Jun 24.

Department of Medical Sciences and Public Health, Multiple Sclerosis Centre, University of Cagliari, Cagliari, Italy.

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http://dx.doi.org/10.1136/bmjspcare-2017-001324DOI Listing
March 2018

Localized pigmentation disorder after subcutaneous pegylated interferon beta-1a injection.

Mult Scler 2018 02 28;24(2):231-233. Epub 2017 Jul 28.

Multiple Sclerosis Center, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.

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http://dx.doi.org/10.1177/1352458517708465DOI Listing
February 2018

Rescue therapy with alemtuzumab in multiple sclerosis post-natalizumab puerperium reactivation.

Neurol Sci 2018 02 7;39(2):389-390. Epub 2017 Oct 7.

Department of Medical Sciences and Public Health, University of Cagliari, Multiple Sclerosis Centre, Ospedale Binaghi, Via Is Guadazzonis, 2, 09126, Cagliari, Italy.

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http://link.springer.com/10.1007/s10072-017-3135-y
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http://dx.doi.org/10.1007/s10072-017-3135-yDOI Listing
February 2018

Long-term follow-up more than 10 years after HSCT: a monocentric experience.

J Neurol 2018 Feb 21;265(2):410-416. Epub 2017 Dec 21.

Department of Medical Sciences and Public Health, Multiple Sclerosis Center, ATS Sardegna, Ospedale Binaghi, University of Cagliari, Via Is Guadazzonis 2, 09126, Cagliari, Italy.

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http://dx.doi.org/10.1007/s00415-017-8718-2DOI Listing
February 2018

Intrathecal oligoclonal bands synthesis in multiple sclerosis: is it always a prognostic factor?

J Neurol 2018 Feb 22;265(2):424-430. Epub 2017 Dec 22.

Multiple Sclerosis Center, Department of Medical Sciences and Public Health, University of Cagliari, Via Is Guadazzonis 2, 09126, Cagliari, Italy.

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http://dx.doi.org/10.1007/s00415-017-8716-4DOI Listing
February 2018

Pulse steroid therapy in multiple sclerosis and mood changes: An exploratory prospective study.

Mult Scler Relat Disord 2018 Feb 31;20:104-108. Epub 2018 Jan 31.

Multiple Sclerosis Center, Binaghi Hospital, ATS Sardegna, Department of Medical Sciences and Public Health, University of Cagliari, via Is Guadazzonis, 2, 09126 Cagliari, Italy.

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http://dx.doi.org/10.1016/j.msard.2018.01.012DOI Listing
February 2018

PML in a person with multiple sclerosis: Is teriflunomide the felon?

Neurology 2018 01 6;90(2):83-85. Epub 2017 Dec 6.

From University of Cagliari (L.L., G.F., J.F., G.C., M.G.M., E.C.); IRCCS San Raffaele Hospital (S.G.), Milan; and Binaghi Hospital (M.A.B., F.C.), ATS Sardegna, Italy.

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http://dx.doi.org/10.1212/WNL.0000000000004804DOI Listing
January 2018

Metabolomic analysis identifies altered metabolic pathways in Multiple Sclerosis.

Int J Biochem Cell Biol 2017 12 16;93:148-155. Epub 2017 Jul 16.

Department of Biomedical Sciences, University of Cagliari, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2017.07.004DOI Listing
December 2017

'Timed up and go' and brain atrophy: a preliminary MRI study to assess functional mobility performance in multiple sclerosis.

J Neurol 2017 Nov 11;264(11):2201-2204. Epub 2017 Sep 11.

Multiple Sclerosis Center, Department of Medical Sciences and Public Health, Binaghi Hospital, University of Cagliari, Via Is Guadazzonis 2, 09126, Cagliari, Italy.

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http://dx.doi.org/10.1007/s00415-017-8612-yDOI Listing
November 2017

Are static and functional balance abilities related in individuals with Multiple Sclerosis?

Mult Scler Relat Disord 2017 Jul 11;15:1-6. Epub 2017 Apr 11.

Multiple Sclerosis Centre, Department of Medical Sciences and Public Health University of Cagliari, Cagliari, Italy.

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http://dx.doi.org/10.1016/j.msard.2017.04.002DOI Listing
July 2017

Charcot-Marie-Tooth disease: genetic subtypes in the Sardinian population.

Neurol Sci 2017 Jun 13;38(6):1019-1025. Epub 2017 Mar 13.

Multiple Sclerosis Centre, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.

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http://dx.doi.org/10.1007/s10072-017-2905-xDOI Listing
June 2017

Overexpression of the Cytokine BAFF and Autoimmunity Risk.

N Engl J Med 2017 04;376(17):1615-1626

From Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche Monserrato (M.S., V.O., M.L.I., M. Pitzalis, M. Pala, C.S., V.F., M.F., M. Deiana, I.A., E.P., A. Mulas, M.G.P., M. Lobina, S.L., Mara Marongiu, V.S., Michele Marongiu, G.S., F.B., A. Maschio, F.D., M. Dei, F.V., S.O., A.A., M.B.W., A. Meloni, S. Sanna, E.F., M.Z., F.C.), Center for Advanced Studies, Research, and Development in Sardinia, Parco Scientifico e Tecnologico della Sardegna (I.Z., M.F., R.C., G. Cuccuru), Struttura Complessa Disciplina di Ematologia e Centro Trapianto Cellule Staminali Emopoietiche Wilma Deplano, Ospedale Oncologico di Riferimento Regionale Armando Businco (M. Pani), Dipartimento di Sanità Pubblica, Medicina Clinica e Molecolare, Università di Cagliari (E.C., J.F., G. Coghe, L.L., G. Fenu), Azienda Ospedaliera Brotzu, S.C. Neurologia (P.F., M. Melis), Division of Rheumatology, University and University Hospital of Cagliari (M. Piga, A. Mathieu), Department of Medical Sciences M. Aresu, University of Cagliari (D.F., S.D.G., M.G.M.), Azienda Ospedaliera Brotzu, U.S. Gastroenterologia Pediatrica Ospedale Pediatrico Microcitemico A. Cao (M.C.), and Nephrology, Dialysis, and Transplantation Unit, Giuseppe Brotzu Hospital (A.P.), Cagliari, Dipartimento di Scienze Biomediche, Università degli Studi di Sassari (M.F., F.P., F.C.), Unit of Neurology, Department of Clinical and Experimental Medicine, University of Sassari (G. Farina, G.R.), and Servizio Trasfusionale (M.A.S.) and Clinica Medica (A.D.), Azienda Ospedaliero Universitaria di Sassari, Sassari, Neurology B, Department of Neurological, Biomedical, and Movement Sciences, University of Verona, Verona (G. Farina), Department of Health Sciences, Interdisciplinary Research Center of Autoimmune Diseases, University of Eastern Piedmont, Novara (N.B., S.D.), SC Neurologia, Dipartimento di Scienze Mediche, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) Casa Sollievo della Sofferenza, San Giovanni Rotondo (M. Leone), Don C. Gnocchi Foundation IRCCS (F.R.G.), and Referral Center for Systemic Autoimmune Diseases Fondazione IRCCS Cá Granda Ospedale Maggiore Policlinico and University of Milan (M. Marchini), Milan, and Dipartimento di Scienze Cliniche e Molecolari, Università Politecnica delle Marche e Ospedali Riuniti, Ancona (M.G.D.) - all in Italy; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore (M.L.I., M.G., D.S.); the Department of Clinical Neurosciences (M.B., S. Sawcer) and JDRF-Wellcome Trust Diabetes and Inflammation Laboratory, National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research (J.A.T.), University of Cambridge, Cambridge, United Kingdom; Department of Clinical Neuroscience, Karolinska Institutet at Karolinska University Hospital Solna (I.K., I.L.B., T.O., J.H.), Institute of Environmental Medicine (L.A.) and Institute of Environmental Medicine, Unit of Immunology and Chronic Disease (M.E.A.R.), Karolinska Institute, and Center for Occupational and Environmental Medicine, Stockholm County Council (L.A.), Stockholm; Department of Functional Biology, University of Oviedo, Oviedo (A.S.), Rheumatology Department, Hospital Universitario 12 de Octubre, Madrid (P.E.C.), Department of Internal Medicine, Hospital Universitario Virgen del Rocío, Seville (M.J.C.-P.), Laboratorio de Investigacion 10 and Rheumatology Unit, Instituto de Investigacion Sanitaria-Hospital Clinico Universitario de Santiago, Santiago de Compostela (A.G.), and Centro de Genómica e Investigación Oncológica, Pfizer-Universidad de Granada-Junta de Andalucía, Granada (M.E.A.R.) - all in Spain; Department of Human Genetics, University of Chicago, Chicago (J.H.M., J.N.); Centro Hospitalar do Porto-Hospital Santo Antonio and Unit for Multidisciplinary Research in Biomedicine-Unidade Multidisciplinar de Investigação Biomédica, Porto, Portugal (B.M.S.); Departments of Pathology and Genetics, Stanford University, Stanford, CA (S.B.M.); and Center for Statistical Genetics, University of Michigan, Ann Arbor (G.R.A.).

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http://dx.doi.org/10.1056/NEJMoa1610528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605835PMC
April 2017

Perception of risk and shared decision making process in multiple sclerosis.

Expert Rev Neurother 2017 02 4;17(2):173-180. Epub 2016 Aug 4.

b Department of Medical Science , University of Cagliari , Cagliari , Italy.

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http://dx.doi.org/10.1080/14737175.2016.1217155DOI Listing
February 2017

Clinical assessment of gait in individuals with multiple sclerosis using wearable inertial sensors: Comparison with patient-based measure.

Mult Scler Relat Disord 2016 Nov 27;10:187-191. Epub 2016 Oct 27.

Multiple Sclerosis Centre, Department of Medical Sciences and Public Health University of Cagliari, Cagliari, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S22110348163019
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http://dx.doi.org/10.1016/j.msard.2016.10.007DOI Listing
November 2016

Facial synkinesis as a first symptom of multiple sclerosis.

Mult Scler 2016 10 5;22(11):1499-1501. Epub 2015 Aug 5.

Clinica Neurologica, Azienda Ospedaliero-Universitaria di Cagliari, Italy.

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http://dx.doi.org/10.1177/1352458515584415DOI Listing
October 2016

(1)H-NMR analysis provides a metabolomic profile of patients with multiple sclerosis.

Neurol Neuroimmunol Neuroinflamm 2016 Feb 24;3(1):e185. Epub 2015 Dec 24.

Department of Public Health (E.C., L.L., L.B., S.P., J.F., G.F., G.C., M.R.M., R.M.), Clinical and Molecular Medicine, Department of Biomedical Sciences (F.M., F.D.C., L.A.), and Department of Medical Science (M.G.M.), University of Cagliari, Cagliari, Italy.

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http://dx.doi.org/10.1212/NXI.0000000000000185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694073PMC
February 2016

Progressive multiple sclerosis and mood disorders.

Neurol Sci 2015 Sep 22;36(9):1625-31. Epub 2015 Apr 22.

Department of Public Health and Clinical and Molecular Medicine, Multiple Sclerosis Center, University of Cagliari, Cagliari, Italy,

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http://dx.doi.org/10.1007/s10072-015-2220-3DOI Listing
September 2015

Monoclonal antibodies: a target therapy for multiple sclerosis.

Inflamm Allergy Drug Targets 2014 ;13(2):134-43

Ospedale Binaghi, Via Is guadazzonis 2, 09126, Cagliari, Italy.

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http://dx.doi.org/10.2174/1871528113666140513114815DOI Listing
February 2015

Long-term benefits of induction therapy in NMO: a case report.

Neurol Sci 2014 Nov 18;35(11):1831-2. Epub 2014 May 18.

Department of Public Health, Clinical and Molecular Medicine, Multiple Sclerosis Center, University of Cagliari, Via Is Guadazzonis n. 2, 09126, Cagliari, Italy,

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http://dx.doi.org/10.1007/s10072-014-1830-5DOI Listing
November 2014

Post-natalizumab clinical and radiological findings in a cohort of multiple sclerosis patients: 12-month follow-up.

Neurol Sci 2014 Mar 30;35(3):401-8. Epub 2013 Aug 30.

1 Multiple Sclerosis Centre, Department of Public Health, Clinical and Molecular Medicine, University of Cagliari, Cagliari, Italy,

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http://dx.doi.org/10.1007/s10072-013-1527-1DOI Listing
March 2014

What do multiple sclerosis patients and their caregivers perceive as unmet needs?

BMC Neurol 2013 Nov 15;13:177. Epub 2013 Nov 15.

Multiple Sclerosis Center, University of Cagliari, via Is Guadazzonis, 2, Cagliari 09126, Italy.

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http://dx.doi.org/10.1186/1471-2377-13-177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840560PMC
November 2013