Lon S Schneider

Lon S Schneider

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Lon S Schneider

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The risks and uses of dietary supplements.

Authors:
Lon S Schneider

Lancet Neurol 2019 Sep;18(9):814

Keck School of Medicine of the University of Southern California, Los Angeles, CA 90089, USA. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(19)30293-5DOI Listing
September 2019

Vascular dysfunction-The disregarded partner of Alzheimer's disease.

Alzheimers Dement 2019 01;15(1):158-167

Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Alzheimer's Disease Research Center, Keck School of Medicine at the University of Southern California, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2018.07.222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338083PMC
January 2019

Evaluation of Medicare Claims Data as a Tool to Identify Dementia.

J Alzheimers Dis 2019 ;67(2):769-778

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.3233/JAD-181005DOI Listing
January 2019

Analysis of shared heritability in common disorders of the brain.

Authors:
Verneri Anttila Brendan Bulik-Sullivan Hilary K Finucane Raymond K Walters Jose Bras Laramie Duncan Valentina Escott-Price Guido J Falcone Padhraig Gormley Rainer Malik Nikolaos A Patsopoulos Stephan Ripke Zhi Wei Dongmei Yu Phil H Lee Patrick Turley Benjamin Grenier-Boley Vincent Chouraki Yoichiro Kamatani Claudine Berr Luc Letenneur Didier Hannequin Philippe Amouyel Anne Boland Jean-François Deleuze Emmanuelle Duron Badri N Vardarajan Christiane Reitz Alison M Goate Matthew J Huentelman M Ilyas Kamboh Eric B Larson Ekaterina Rogaeva Peter St George-Hyslop Hakon Hakonarson Walter A Kukull Lindsay A Farrer Lisa L Barnes Thomas G Beach F Yesim Demirci Elizabeth Head Christine M Hulette Gregory A Jicha John S K Kauwe Jeffrey A Kaye James B Leverenz Allan I Levey Andrew P Lieberman Vernon S Pankratz Wayne W Poon Joseph F Quinn Andrew J Saykin Lon S Schneider Amanda G Smith Joshua A Sonnen Robert A Stern Vivianna M Van Deerlin Linda J Van Eldik Denise Harold Giancarlo Russo David C Rubinsztein Anthony Bayer Magda Tsolaki Petra Proitsi Nick C Fox Harald Hampel Michael J Owen Simon Mead Peter Passmore Kevin Morgan Markus M Nöthen Martin Rossor Michelle K Lupton Per Hoffmann Johannes Kornhuber Brian Lawlor Andrew McQuillin Ammar Al-Chalabi Joshua C Bis Agustin Ruiz Mercè Boada Sudha Seshadri Alexa Beiser Kenneth Rice Sven J van der Lee Philip L De Jager Daniel H Geschwind Matthias Riemenschneider Steffi Riedel-Heller Jerome I Rotter Gerhard Ransmayr Bradley T Hyman Carlos Cruchaga Montserrat Alegret Bendik Winsvold Priit Palta Kai-How Farh Ester Cuenca-Leon Nicholas Furlotte Tobias Kurth Lannie Ligthart Gisela M Terwindt Tobias Freilinger Caroline Ran Scott D Gordon Guntram Borck Hieab H H Adams Terho Lehtimäki Juho Wedenoja Julie E Buring Markus Schürks Maria Hrafnsdottir Jouke-Jan Hottenga Brenda Penninx Ville Artto Mari Kaunisto Salli Vepsäläinen Nicholas G Martin Grant W Montgomery Mitja I Kurki Eija Hämäläinen Hailiang Huang Jie Huang Cynthia Sandor Caleb Webber Bertram Muller-Myhsok Stefan Schreiber Veikko Salomaa Elizabeth Loehrer Hartmut Göbel Alfons Macaya Patricia Pozo-Rosich Thomas Hansen Thomas Werge Jaakko Kaprio Andres Metspalu Christian Kubisch Michel D Ferrari Andrea C Belin Arn M J M van den Maagdenberg John-Anker Zwart Dorret Boomsma Nicholas Eriksson Jes Olesen Daniel I Chasman Dale R Nyholt Andreja Avbersek Larry Baum Samuel Berkovic Jonathan Bradfield Russell J Buono Claudia B Catarino Patrick Cossette Peter De Jonghe Chantal Depondt Dennis Dlugos Thomas N Ferraro Jacqueline French Helle Hjalgrim Jennifer Jamnadas-Khoda Reetta Kälviäinen Wolfram S Kunz Holger Lerche Costin Leu Dick Lindhout Warren Lo Daniel Lowenstein Mark McCormack Rikke S Møller Anne Molloy Ping-Wing Ng Karen Oliver Michael Privitera Rodney Radtke Ann-Kathrin Ruppert Thomas Sander Steven Schachter Christoph Schankin Ingrid Scheffer Susanne Schoch Sanjay M Sisodiya Philip Smith Michael Sperling Pasquale Striano Rainer Surges G Neil Thomas Frank Visscher Christopher D Whelan Federico Zara Erin L Heinzen Anthony Marson Felicitas Becker Hans Stroink Fritz Zimprich Thomas Gasser Raphael Gibbs Peter Heutink Maria Martinez Huw R Morris Manu Sharma Mina Ryten Kin Y Mok Sara Pulit Steve Bevan Elizabeth Holliday John Attia Thomas Battey Giorgio Boncoraglio Vincent Thijs Wei-Min Chen Braxton Mitchell Peter Rothwell Pankaj Sharma Cathie Sudlow Astrid Vicente Hugh Markus Christina Kourkoulis Joana Pera Miriam Raffeld Scott Silliman Vesna Boraska Perica Laura M Thornton Laura M Huckins N William Rayner Cathryn M Lewis Monica Gratacos Filip Rybakowski Anna Keski-Rahkonen Anu Raevuori James I Hudson Ted Reichborn-Kjennerud Palmiero Monteleone Andreas Karwautz Katrin Mannik Jessica H Baker Julie K O'Toole Sara E Trace Oliver S P Davis Sietske G Helder Stefan Ehrlich Beate Herpertz-Dahlmann Unna N Danner Annemarie A van Elburg Maurizio Clementi Monica Forzan Elisa Docampo Jolanta Lissowska Joanna Hauser Alfonso Tortorella Mario Maj Fragiskos Gonidakis Konstantinos Tziouvas Hana Papezova Zeynep Yilmaz Gudrun Wagner Sarah Cohen-Woods Stefan Herms Antonio Julià Raquel Rabionet Danielle M Dick Samuli Ripatti Ole A Andreassen Thomas Espeseth Astri J Lundervold Vidar M Steen Dalila Pinto Stephen W Scherer Harald Aschauer Alexandra Schosser Lars Alfredsson Leonid Padyukov Katherine A Halmi James Mitchell Michael Strober Andrew W Bergen Walter Kaye Jin Peng Szatkiewicz Bru Cormand Josep Antoni Ramos-Quiroga Cristina Sánchez-Mora Marta Ribasés Miguel Casas Amaia Hervas Maria Jesús Arranz Jan Haavik Tetyana Zayats Stefan Johansson Nigel Williams Astrid Dempfle Aribert Rothenberger Jonna Kuntsi Robert D Oades Tobias Banaschewski Barbara Franke Jan K Buitelaar Alejandro Arias Vasquez Alysa E Doyle Andreas Reif Klaus-Peter Lesch Christine Freitag Olga Rivero Haukur Palmason Marcel Romanos Kate Langley Marcella Rietschel Stephanie H Witt Soeren Dalsgaard Anders D Børglum Irwin Waldman Beth Wilmot Nikolas Molly Claiton H D Bau Jennifer Crosbie Russell Schachar Sandra K Loo James J McGough Eugenio H Grevet Sarah E Medland Elise Robinson Lauren A Weiss Elena Bacchelli Anthony Bailey Vanessa Bal Agatino Battaglia Catalina Betancur Patrick Bolton Rita Cantor Patrícia Celestino-Soper Geraldine Dawson Silvia De Rubeis Frederico Duque Andrew Green Sabine M Klauck Marion Leboyer Pat Levitt Elena Maestrini Shrikant Mane Daniel Moreno- De-Luca Jeremy Parr Regina Regan Abraham Reichenberg Sven Sandin Jacob Vorstman Thomas Wassink Ellen Wijsman Edwin Cook Susan Santangelo Richard Delorme Bernadette Rogé Tiago Magalhaes Dan Arking Thomas G Schulze Robert C Thompson Jana Strohmaier Keith Matthews Ingrid Melle Derek Morris Douglas Blackwood Andrew McIntosh Sarah E Bergen Martin Schalling Stéphane Jamain Anna Maaser Sascha B Fischer Céline S Reinbold Janice M Fullerton José Guzman-Parra Fermin Mayoral Peter R Schofield Sven Cichon Thomas W Mühleisen Franziska Degenhardt Johannes Schumacher Michael Bauer Philip B Mitchell Elliot S Gershon John Rice James B Potash Peter P Zandi Nick Craddock I Nicol Ferrier Martin Alda Guy A Rouleau Gustavo Turecki Roel Ophoff Carlos Pato Adebayo Anjorin Eli Stahl Markus Leber Piotr M Czerski Cristiana Cruceanu Ian R Jones Danielle Posthuma Till F M Andlauer Andreas J Forstner Fabian Streit Bernhard T Baune Tracy Air Grant Sinnamon Naomi R Wray Donald J MacIntyre David Porteous Georg Homuth Margarita Rivera Jakob Grove Christel M Middeldorp Ian Hickie Michele Pergadia Divya Mehta Johannes H Smit Rick Jansen Eco de Geus Erin Dunn Qingqin S Li Matthias Nauck Robert A Schoevers Aartjan Tf Beekman James A Knowles Alexander Viktorin Paul Arnold Cathy L Barr Gabriel Bedoya-Berrio O Joseph Bienvenu Helena Brentani Christie Burton Beatriz Camarena Carolina Cappi Danielle Cath Maria Cavallini Daniele Cusi Sabrina Darrow Damiaan Denys Eske M Derks Andrea Dietrich Thomas Fernandez Martijn Figee Nelson Freimer Gloria Gerber Marco Grados Erica Greenberg Gregory L Hanna Andreas Hartmann Matthew E Hirschtritt Pieter J Hoekstra Alden Huang Chaim Huyser Cornelia Illmann Michael Jenike Samuel Kuperman Bennett Leventhal Christine Lochner Gholson J Lyon Fabio Macciardi Marcos Madruga-Garrido Irene A Malaty Athanasios Maras Lauren McGrath Eurípedes C Miguel Pablo Mir Gerald Nestadt Humberto Nicolini Michael S Okun Andrew Pakstis Peristera Paschou John Piacentini Christopher Pittenger Kerstin Plessen Vasily Ramensky Eliana M Ramos Victor Reus Margaret A Richter Mark A Riddle Mary M Robertson Veit Roessner Maria Rosário Jack F Samuels Paul Sandor Dan J Stein Fotis Tsetsos Filip Van Nieuwerburgh Sarah Weatherall Jens R Wendland Tomasz Wolanczyk Yulia Worbe Gwyneth Zai Fernando S Goes Nicole McLaughlin Paul S Nestadt Hans-Jorgen Grabe Christel Depienne Anuar Konkashbaev Nuria Lanzagorta Ana Valencia-Duarte Elvira Bramon Nancy Buccola Wiepke Cahn Murray Cairns Siow A Chong David Cohen Benedicto Crespo-Facorro James Crowley Michael Davidson Lynn DeLisi Timothy Dinan Gary Donohoe Elodie Drapeau Jubao Duan Lieuwe Haan David Hougaard Sena Karachanak-Yankova Andrey Khrunin Janis Klovins Vaidutis Kučinskas Jimmy Lee Chee Keong Svetlana Limborska Carmel Loughland Jouko Lönnqvist Brion Maher Manuel Mattheisen Colm McDonald Kieran C Murphy Igor Nenadic Jim van Os Christos Pantelis Michele Pato Tracey Petryshen Digby Quested Panos Roussos Alan R Sanders Ulrich Schall Sibylle G Schwab Kang Sim Hon-Cheong So Elisabeth Stögmann Mythily Subramaniam Draga Toncheva John Waddington James Walters Mark Weiser Wei Cheng Robert Cloninger David Curtis Pablo V Gejman Frans Henskens Morten Mattingsdal Sang-Yun Oh Rodney Scott Bradley Webb Gerome Breen Claire Churchhouse Cynthia M Bulik Mark Daly Martin Dichgans Stephen V Faraone Rita Guerreiro Peter Holmans Kenneth S Kendler Bobby Koeleman Carol A Mathews Alkes Price Jeremiah Scharf Pamela Sklar Julie Williams Nicholas W Wood Chris Cotsapas Aarno Palotie Jordan W Smoller Patrick Sullivan Jonathan Rosand Aiden Corvin Benjamin M Neale Jonathan M Schott Richard Anney Josephine Elia Maria Grigoroiu-Serbanescu Howard J Edenberg Robin Murray

Science 2018 06;360(6395)

Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.

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http://dx.doi.org/10.1126/science.aap8757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097237PMC
June 2018

Precision pharmacology for Alzheimer's disease.

Pharmacol Res 2018 04 16;130:331-365. Epub 2018 Feb 16.

AXA Research Fund & Sorbonne University Chair, Paris, France; Sorbonne University, GRC No. 21, Alzheimer Precision Medicine (APM), AP-HP, Pitié-Salpêtrière Hospital, Boulevard de l'hôpital, F-75013, Paris, France; Brain & Spine Institute (ICM), INSERM U 1127, CNRS UMR 7225, Boulevard de l'hôpital, F-75013, Paris, France; Institute of Memory and Alzheimer's Disease (IM2A), Department of Neurology, Pitié-Salpêtrière Hospital, AP-HP, Boulevard de l'hôpital, F-75013, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2018.02.014DOI Listing
April 2018

Pimavanserin for patients with Alzheimer's disease psychosis.

Authors:
Lon S Schneider

Lancet Neurol 2018 03;17(3):194-195

Department of Psychiatry and the Behavioral Sciences and Department of Neurology, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033, USA. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(18)30052-8DOI Listing
March 2018

Data-driven identification of endophenotypes of Alzheimer's disease progression: implications for clinical trials and therapeutic interventions.

Alzheimers Res Ther 2018 01 15;10(1). Epub 2018 Jan 15.

Department of Pharmacology, College of Medicine, University of Arizona, Tucson, AZ, USA.

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http://dx.doi.org/10.1186/s13195-017-0332-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389228PMC
January 2018

Challenging Assumptions About African American Participation in Alzheimer Disease Trials.

Am J Geriatr Psychiatry 2017 Oct 25;25(10):1150-1159. Epub 2017 Apr 25.

Departments of Psychiatry, Neurology, and Gerontology, University of Southern California Keck School of Medicine, Los Angeles, CA.

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http://dx.doi.org/10.1016/j.jagp.2017.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5842064PMC
October 2017

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.

Authors:
Rebecca Sims Sven J van der Lee Adam C Naj Céline Bellenguez Nandini Badarinarayan Johanna Jakobsdottir Brian W Kunkle Anne Boland Rachel Raybould Joshua C Bis Eden R Martin Benjamin Grenier-Boley Stefanie Heilmann-Heimbach Vincent Chouraki Amanda B Kuzma Kristel Sleegers Maria Vronskaya Agustin Ruiz Robert R Graham Robert Olaso Per Hoffmann Megan L Grove Badri N Vardarajan Mikko Hiltunen Markus M Nöthen Charles C White Kara L Hamilton-Nelson Jacques Epelbaum Wolfgang Maier Seung-Hoan Choi Gary W Beecham Cécile Dulary Stefan Herms Albert V Smith Cory C Funk Céline Derbois Andreas J Forstner Shahzad Ahmad Hongdong Li Delphine Bacq Denise Harold Claudia L Satizabal Otto Valladares Alessio Squassina Rhodri Thomas Jennifer A Brody Liming Qu Pascual Sánchez-Juan Taniesha Morgan Frank J Wolters Yi Zhao Florentino Sanchez Garcia Nicola Denning Myriam Fornage John Malamon Maria Candida Deniz Naranjo Elisa Majounie Thomas H Mosley Beth Dombroski David Wallon Michelle K Lupton Josée Dupuis Patrice Whitehead Laura Fratiglioni Christopher Medway Xueqiu Jian Shubhabrata Mukherjee Lina Keller Kristelle Brown Honghuang Lin Laura B Cantwell Francesco Panza Bernadette McGuinness Sonia Moreno-Grau Jeremy D Burgess Vincenzo Solfrizzi Petra Proitsi Hieab H Adams Mariet Allen Davide Seripa Pau Pastor L Adrienne Cupples Nathan D Price Didier Hannequin Ana Frank-García Daniel Levy Paramita Chakrabarty Paolo Caffarra Ina Giegling Alexa S Beiser Vilmantas Giedraitis Harald Hampel Melissa E Garcia Xue Wang Lars Lannfelt Patrizia Mecocci Gudny Eiriksdottir Paul K Crane Florence Pasquier Virginia Boccardi Isabel Henández Robert C Barber Martin Scherer Lluis Tarraga Perrie M Adams Markus Leber Yuning Chen Marilyn S Albert Steffi Riedel-Heller Valur Emilsson Duane Beekly Anne Braae Reinhold Schmidt Deborah Blacker Carlo Masullo Helena Schmidt Rachelle S Doody Gianfranco Spalletta W T Longstreth Thomas J Fairchild Paola Bossù Oscar L Lopez Matthew P Frosch Eleonora Sacchinelli Bernardino Ghetti Qiong Yang Ryan M Huebinger Frank Jessen Shuo Li M Ilyas Kamboh John Morris Oscar Sotolongo-Grau Mindy J Katz Chris Corcoran Melanie Dunstan Amy Braddel Charlene Thomas Alun Meggy Rachel Marshall Amy Gerrish Jade Chapman Miquel Aguilar Sarah Taylor Matt Hill Mònica Díez Fairén Angela Hodges Bruno Vellas Hilkka Soininen Iwona Kloszewska Makrina Daniilidou James Uphill Yogen Patel Joseph T Hughes Jenny Lord James Turton Annette M Hartmann Roberta Cecchetti Chiara Fenoglio Maria Serpente Marina Arcaro Carlo Caltagirone Maria Donata Orfei Antonio Ciaramella Sabrina Pichler Manuel Mayhaus Wei Gu Alberto Lleó Juan Fortea Rafael Blesa Imelda S Barber Keeley Brookes Chiara Cupidi Raffaele Giovanni Maletta David Carrell Sandro Sorbi Susanne Moebus Maria Urbano Alberto Pilotto Johannes Kornhuber Paolo Bosco Stephen Todd David Craig Janet Johnston Michael Gill Brian Lawlor Aoibhinn Lynch Nick C Fox John Hardy Roger L Albin Liana G Apostolova Steven E Arnold Sanjay Asthana Craig S Atwood Clinton T Baldwin Lisa L Barnes Sandra Barral Thomas G Beach James T Becker Eileen H Bigio Thomas D Bird Bradley F Boeve James D Bowen Adam Boxer James R Burke Jeffrey M Burns Joseph D Buxbaum Nigel J Cairns Chuanhai Cao Chris S Carlson Cynthia M Carlsson Regina M Carney Minerva M Carrasquillo Steven L Carroll Carolina Ceballos Diaz Helena C Chui David G Clark David H Cribbs Elizabeth A Crocco Charles DeCarli Malcolm Dick Ranjan Duara Denis A Evans Kelley M Faber Kenneth B Fallon David W Fardo Martin R Farlow Steven Ferris Tatiana M Foroud Douglas R Galasko Marla Gearing Daniel H Geschwind John R Gilbert Neill R Graff-Radford Robert C Green John H Growdon Ronald L Hamilton Lindy E Harrell Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Erin Abner Lee-Way Jin Gyungah Jun Anna Karydas Jeffrey A Kaye Ronald Kim Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Ge Li Andrew P Lieberman Kathryn L Lunetta Constantine G Lyketsos Daniel C Marson Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller John C Morris Jill R Murrell Amanda J Myers Sid O'Bryant John M Olichney Vernon S Pankratz Joseph E Parisi Henry L Paulson William Perry Elaine Peskind Aimee Pierce Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Murray Raskind Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Ekaterina Rogaeva Howard J Rosen Roger N Rosenberg Mark A Sager Andrew J Saykin Julie A Schneider Lon S Schneider William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Rudolph E Tanzi Tricia A Thornton-Wells John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Fabienne Garzia Feroze Golamaully Gislain Septier Sebastien Engelborghs Rik Vandenberghe Peter P De Deyn Carmen Muñoz Fernadez Yoland Aladro Benito Hakan Thonberg Charlotte Forsell Lena Lilius Anne Kinhult-Stählbom Lena Kilander RoseMarie Brundin Letizia Concari Seppo Helisalmi Anne Maria Koivisto Annakaisa Haapasalo Vincent Dermecourt Nathalie Fievet Olivier Hanon Carole Dufouil Alexis Brice Karen Ritchie Bruno Dubois Jayanadra J Himali C Dirk Keene JoAnn Tschanz Annette L Fitzpatrick Walter A Kukull Maria Norton Thor Aspelund Eric B Larson Ron Munger Jerome I Rotter Richard B Lipton María J Bullido Albert Hofman Thomas J Montine Eliecer Coto Eric Boerwinkle Ronald C Petersen Victoria Alvarez Fernando Rivadeneira Eric M Reiman Maura Gallo Christopher J O'Donnell Joan S Reisch Amalia Cecilia Bruni Donald R Royall Martin Dichgans Mary Sano Daniela Galimberti Peter St George-Hyslop Elio Scarpini Debby W Tsuang Michelangelo Mancuso Ubaldo Bonuccelli Ashley R Winslow Antonio Daniele Chuang-Kuo Wu Oliver Peters Benedetta Nacmias Matthias Riemenschneider Reinhard Heun Carol Brayne David C Rubinsztein Jose Bras Rita Guerreiro Ammar Al-Chalabi Christopher E Shaw John Collinge David Mann Magda Tsolaki Jordi Clarimón Rebecca Sussams Simon Lovestone Michael C O'Donovan Michael J Owen Timothy W Behrens Simon Mead Alison M Goate Andre G Uitterlinden Clive Holmes Carlos Cruchaga Martin Ingelsson David A Bennett John Powell Todd E Golde Caroline Graff Philip L De Jager Kevin Morgan Nilufer Ertekin-Taner Onofre Combarros Bruce M Psaty Peter Passmore Steven G Younkin Claudine Berr Vilmundur Gudnason Dan Rujescu Dennis W Dickson Jean-François Dartigues Anita L DeStefano Sara Ortega-Cubero Hakon Hakonarson Dominique Campion Merce Boada John Keoni Kauwe Lindsay A Farrer Christine Van Broeckhoven M Arfan Ikram Lesley Jones Jonathan L Haines Christophe Tzourio Lenore J Launer Valentina Escott-Price Richard Mayeux Jean-François Deleuze Najaf Amin Peter A Holmans Margaret A Pericak-Vance Philippe Amouyel Cornelia M van Duijn Alfredo Ramirez Li-San Wang Jean-Charles Lambert Sudha Seshadri Julie Williams Gerard D Schellenberg

Nat Genet 2017 09 17;49(9):1373-1384. Epub 2017 Jul 17.

Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ng.3916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669039PMC
September 2017

Lessons from the Multidomain Alzheimer Preventive Trial.

Lancet Neurol 2017 08 11;16(8):585-586. Epub 2017 Jul 11.

Keck School of Medicine of USC, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1016/S1474-4422(17)30227-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812698PMC
August 2017

Preventing Dementia: Many Issues and Not Enough Time.

JAMA Neurol 2017 05;74(5):508-510

Alzheimer's Disease Research Center, Departments of Psychiatry and the Behavioral Sciences and Neurology, Keck School of Medicine of the University of Southern California, Los Angeles.

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http://dx.doi.org/10.1001/jamaneurol.2017.0045DOI Listing
May 2017

Dementia research priorities-1 - Author's reply.

Authors:
Lon S Schneider

Lancet Neurol 2017 03 15;16(3):181. Epub 2017 Feb 15.

Keck School of Medicine of USC, Los Angeles, CA 90033, USA. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(17)30019-4DOI Listing
March 2017

Dementia research priorities-2 - Author's reply.

Authors:
Lon S Schneider

Lancet Neurol 2017 03 15;16(3):182. Epub 2017 Feb 15.

Keck School of Medicine of USC, Los Angeles, CA 90033, USA. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(17)30018-2DOI Listing
March 2017

Evidence for benefit of statins to modify cognitive decline and risk in Alzheimer's disease.

Alzheimers Res Ther 2017 Feb 17;9(1):10. Epub 2017 Feb 17.

Institute for Computational Health Sciences, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1186/s13195-017-0237-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316146PMC
February 2017

Post Hoc Analyses of ApoE Genotype-Defined Subgroups in Clinical Trials.

J Alzheimers Dis 2016 ;50(4):1205-15

University of Southern California Keck School of Medicine, Los Angeles, CA, USA.

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http://dx.doi.org/10.3233/JAD-150847DOI Listing
December 2016

WHO's dementia research priorities: a prescription for failure?

Authors:
Lon S Schneider

Lancet Neurol 2016 11 11;15(12):1202-1203. Epub 2016 Oct 11.

Keck School of Medicine of USC, Los Angeles, CA 90033, USA. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(16)30258-7DOI Listing
November 2016

Reduce vascular risk to prevent dementia?

Authors:
Lon S Schneider

Lancet 2016 Aug 27;388(10046):738-40. Epub 2016 Jul 27.

Department of Psychiatry and the Behavioral Sciences, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033, USA; Department of Neurology, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033, USA. Electronic address:

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http://dx.doi.org/10.1016/S0140-6736(16)31129-1DOI Listing
August 2016

Mortality risk in current and new antipsychotic Alzheimer's disease users: Large scale Japanese study.

Alzheimers Dement 2016 07 19;12(7):823-30. Epub 2016 Apr 19.

Keck School of Medicine, University of Southern California, Los Angeles, USA.

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http://dx.doi.org/10.1016/j.jalz.2016.03.006DOI Listing
July 2016

Predicting disease progression in progressive supranuclear palsy in multicenter clinical trials.

Parkinsonism Relat Disord 2016 07 18;28:41-48. Epub 2016 Apr 18.

Memory and Aging Center, Department of Neurology, University of California San Francisco, 675 Nelson Rising Lane, Suite 190, San Francisco, CA, USA 94158.

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http://dx.doi.org/10.1016/j.parkreldis.2016.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4914418PMC
July 2016

The effect of APOE genotype on the delivery of DHA to cerebrospinal fluid in Alzheimer's disease.

Alzheimers Res Ther 2016 06 30;8:25. Epub 2016 Jun 30.

Department of Neurology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1186/s13195-016-0194-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928349PMC
June 2016

Heterogeneity of Treatment Response to Citalopram for Patients With Alzheimer's Disease With Aggression or Agitation: The CitAD Randomized Clinical Trial.

Am J Psychiatry 2016 May 15;173(5):465-72. Epub 2016 Jan 15.

From the Department of Psychiatry and Behavioral Sciences and the Department of Neurology, Keck School of Medicine of University of Southern California, Los Angeles; the Department of Biostatistics, the Department of Epidemiology, and the Center for Clinical Trials and Evidence Synthesis, Johns Hopkins Bloomberg School of Public Health, Baltimore; the Division of Geriatric Psychiatry, Department of Psychiatry, New York State Psychiatric Institute and Columbia University Medical Center, New York; the Department of Psychiatry and Behavioral Sciences, Johns Hopkins Medicine, Baltimore; the Clinical Biotechnology Research Institute, Roper St. Francis Healthcare, Charleston, S.C.; the Campbell Institute, Centre for Addiction and Mental Health, and the Department of Psychiatry, University of Toronto, Toronto; the Culture and Mental Health Laboratory, University of Southern California, Los Angeles; the Department of Psychiatry, University of Rochester School of Medicine and Dentistry, Rochester, N.Y.; the Biostatistics Consulting Center, Medical College of Wisconsin, Milwaukee; the Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Department of Veterans Affairs Health Care System, Palo Alto, Calif.; and the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford.

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http://dx.doi.org/10.1176/appi.ajp.2015.15050648DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6419726PMC
May 2016

Effects of Citalopram on Neuropsychiatric Symptoms in Alzheimer's Dementia: Evidence From the CitAD Study.

Am J Psychiatry 2016 May 1;173(5):473-80. Epub 2016 Apr 1.

From the Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore; the Johns Hopkins Bloomberg School of Public Health, Baltimore; the Alzheimer's Disease Care, Research, and Education Program, University of Rochester School of Medicine and Dentistry, Rochester, N.Y.; the Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford; the Division of Geriatric Psychiatry, Department of Psychiatry, New York State Psychiatric Institute and College of Physicians and Surgeons of Columbia University, New York; the Clinical Biotechnology Research Institute, Roper St. Francis Healthcare, and the Department of Psychiatry, Ralph H. Johnson VA Medical Center, Charleston, S.C.; the Campbell Institute, Centre for Addiction and Mental Health, and the Department of Psychiatry, University of Toronto, Toronto; the Department of Psychiatry and Behavioral Sciences and the Department of Neurology, Keck School of Medicine of University of Southern California, Los Angeles; and the Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1176/appi.ajp.2016.15020248DOI Listing
May 2016

Accelerating stem cell trials for Alzheimer's disease.

Lancet Neurol 2016 02 17;15(2):219-230. Epub 2015 Dec 17.

Duke Institute for Brain Sciences, Duke University, Durham, NC, USA; Psychiatry Department, Duke University, Durham, NC, USA. Electronic address:

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February 2016

Treatment changes among older patients with dementia treated with antipsychotics.

Int J Geriatr Psychiatry 2015 Dec 11;30(12):1238-49. Epub 2015 Mar 11.

Center for Clinical Management Research, Department of Veterans Affairs, Ann Arbor Healthcare System, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1002/gps.4281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201312PMC
December 2015

Change in agitation in Alzheimer's disease in the placebo arm of a nine-week controlled trial.

Int Psychogeriatr 2015 Dec 25;27(12):2059-67. Epub 2015 Aug 25.

Psychiatry and Behavioral Sciences,Division of Geriatric Psychiatry and Neuropsychiatry,Johns Hopkins School of Medicine,Johns Hopkins Bayview Medical Center,Baltimore,Maryland,USA.

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http://dx.doi.org/10.1017/S1041610215001106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4669064PMC
December 2015

Estimating Mortality Associated With Antipsychotics and Other Psychotropics--Reply.

JAMA Psychiatry 2015 Oct;72(10):1058

Department of Psychiatry, University of Michigan, Ann Arbor2Center for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, Michigan.

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http://dx.doi.org/10.1001/jamapsychiatry.2015.0675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845912PMC
October 2015

Effect of sample size re-estimation in adaptive clinical trials for Alzheimer's disease and mild cognitive impairment.

Alzheimers Dement (N Y) 2015 Jun 14;1(1):63-71. Epub 2015 Apr 14.

Departments of Psychiatry and Neurology, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.trci.2015.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975045PMC
June 2015

Introducing , an open access journal of the Alzheimer's Association.

Authors:
Lon S Schneider

Alzheimers Dement (N Y) 2015 Jun 1;1(1):91-93. Epub 2015 Jul 1.

Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974974PMC
June 2015

Antipsychotics, other psychotropics, and the risk of death in patients with dementia: number needed to harm.

JAMA Psychiatry 2015 May;72(5):438-45

Department of Psychiatry, University of Michigan, Ann Arbor2Center for Clinical Management Research, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan.

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http://dx.doi.org/10.1001/jamapsychiatry.2014.3018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439579PMC
May 2015

World Federation of Societies of Biological Psychiatry guidelines for the pharmacological treatment of dementias in primary care.

Int J Psychiatry Clin Pract 2015 Mar 18;19(1):2-7. Epub 2014 Oct 18.

Department of Psychiatry, University of Düsseldorf, Alexian Research Center Krefeld , Germany.

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March 2015

Differences in Alzheimer disease clinical trial outcomes based on age of the participants.

Neurology 2015 Mar 13;84(11):1121-7. Epub 2015 Feb 13.

From the Departments of Psychiatry and Neurology (L.S.S.), Keck School of Medicine of USC, Los Angeles, CA; Division of Gerontology, Geriatrics, and Palliative Care, Department of Medicine (R.E.K.), and Department of Biostatistics (G.W., G.R.C.), University of Alabama at Birmingham.

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http://dx.doi.org/10.1212/WNL.0000000000001376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4371405PMC
March 2015

Practice effects due to serial cognitive assessment: Implications for preclinical Alzheimer's disease randomized controlled trials.

Alzheimers Dement (Amst) 2015 Mar 29;1(1):103-11. Epub 2015 Mar 29.

Departments of Psychiatry, Neurology, and Gerontology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.dadm.2014.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876902PMC
March 2015

Rarity of the Alzheimer disease-protective APP A673T variant in the United States.

Authors:
Li-San Wang Adam C Naj Robert R Graham Paul K Crane Brian W Kunkle Carlos Cruchaga Josue D Gonzalez Murcia Lisa Cannon-Albright Clinton T Baldwin Henrik Zetterberg Kaj Blennow Walter A Kukull Kelley M Faber Nicole Schupf Maria C Norton JoAnn T Tschanz Ronald G Munger Christopher D Corcoran Ekaterina Rogaeva Chiao-Feng Lin Beth A Dombroski Laura B Cantwell Amanda Partch Otto Valladares Hakon Hakonarson Peter St George-Hyslop Robert C Green Alison M Goate Tatiana M Foroud Regina M Carney Eric B Larson Timothy W Behrens John S K Kauwe Jonathan L Haines Lindsay A Farrer Margaret A Pericak-Vance Richard Mayeux Gerard D Schellenberg Marilyn S Albert Roger L Albin Liana G Apostolova Steven E Arnold Robert Barber Michael Barmada Lisa L Barnes Thomas G Beach James T Becker Gary W Beecham Duane Beekly David A Bennett Eileen H Bigio Thomas D Bird Deborah Blacker Bradley F Boeve James D Bowen Adam Boxer James R Burke Joseph D Buxbaum Nigel J Cairns Chuanhai Cao Chris S Carlson Steven L Carroll Helena C Chui David G Clark David H Cribbs Elizabeth A Crocco Charles DeCarli Steven T DeKosky F Yesim Demirci Malcolm Dick Dennis W Dickson Ranjan Duara Nilufer Ertekin-Taner Kenneth B Fallon Martin R Farlow Steven Ferris Matthew P Frosch Douglas R Galasko Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Jonathan D Glass Neill R Graff-Radford John H Growdon Ronald L Hamilton Kara L Hamilton-Nelson Lindy E Harrell Elizabeth Head Lawrence S Honig Christine M Hulette Bradley T Hyman Gail P Jarvik Gregory A Jicha Lee-Way Jin Gyungah Jun Gyungah Jun M Ilyas Kamboh Anna Karydas Jeffrey A Kaye Ronald Kim Edward H Koo Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Gei Li Andrew P Lieberman Oscar L Lopez Kathryn L Lunetta Constantine G Lyketsos Wendy J Mack Daniel C Marson Eden R Martin Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee W Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Thomas J Montine John C Morris Jill R Murrell John M Olichney Joseph E Parisi William Perry Elaine Peskind Ronald C Petersen Aimee Pierce Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Murray Raskind Eric M Reiman Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Howard J Rosen Roger N Rosenberg Mary Sano Andrew J Saykin Julie A Schneider Lon S Schneider William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Rudolph E Tanzi Tricia A Thornton-Wells John Q Trojanowski Juan C Troncoso Debby W Tsuang Vivianna M Van Deerlin Linda J Van Eldik Badri N Vardarajan Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Sarah Wishnek Randall L Woltjer Clinton B Wright Steven G Younkin Chang-En Yu Lei Yu

JAMA Neurol 2015 Feb;72(2):209-16

Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia.

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http://dx.doi.org/10.1001/jamaneurol.2014.2157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324097PMC
February 2015

Adverse events and dropouts in Alzheimer's disease studies: what can we learn?

Alzheimers Dement 2015 Jan 6;11(1):24-31. Epub 2014 Mar 6.

Department of Psychiatry and the Behavioral Sciences and Department of Neurology, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.jalz.2013.11.008DOI Listing
January 2015

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.

Authors:
Adam C Naj Gyungah Jun Christiane Reitz Brian W Kunkle William Perry Yo Son Park Gary W Beecham Ruchita A Rajbhandary Kara L Hamilton-Nelson Li-San Wang John S K Kauwe Matthew J Huentelman Amanda J Myers Thomas D Bird Bradley F Boeve Clinton T Baldwin Gail P Jarvik Paul K Crane Ekaterina Rogaeva M Michael Barmada F Yesim Demirci Carlos Cruchaga Patricia L Kramer Nilufer Ertekin-Taner John Hardy Neill R Graff-Radford Robert C Green Eric B Larson Peter H St George-Hyslop Joseph D Buxbaum Denis A Evans Julie A Schneider Kathryn L Lunetta M Ilyas Kamboh Andrew J Saykin Eric M Reiman Philip L De Jager David A Bennett John C Morris Thomas J Montine Alison M Goate Deborah Blacker Debby W Tsuang Hakon Hakonarson Walter A Kukull Tatiana M Foroud Eden R Martin Jonathan L Haines Richard P Mayeux Lindsay A Farrer Gerard D Schellenberg Margaret A Pericak-Vance Marilyn S Albert Roger L Albin Liana G Apostolova Steven E Arnold Robert Barber Lisa L Barnes Thomas G Beach James T Becker Duane Beekly Eileen H Bigio James D Bowen Adam Boxer James R Burke Nigel J Cairns Laura B Cantwell Chuanhai Cao Chris S Carlson Regina M Carney Minerva M Carrasquillo Steven L Carroll Helena C Chui David G Clark Jason Corneveaux David H Cribbs Elizabeth A Crocco Charles DeCarli Steven T DeKosky Malcolm Dick Dennis W Dickson Ranjan Duara Kelley M Faber Kenneth B Fallon Martin R Farlow Steven Ferris Matthew P Frosch Douglas R Galasko Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Jonathan D Glass John H Growdon Ronald L Hamilton Lindy E Harrell Elizabeth Head Lawrence S Honig Christine M Hulette Bradley T Hyman Gregory A Jicha Lee-Way Jin Anna Karydas Jeffrey A Kaye Ronald Kim Edward H Koo Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Ge Li Andrew P Lieberman Chiao-Feng Lin Oscar L Lopez Constantine G Lyketsos Wendy J Mack Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Jill R Murrell John M Olichney Vernon S Pankratz Joseph E Parisi Henry L Paulson Elaine Peskind Ronald C Petersen Aimee Pierce Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Murray Raskind Barry Reisberg John M Ringman Erik D Roberson Howard J Rosen Roger N Rosenberg Mary Sano Lon S Schneider William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Rudolph E Tanzi Tricia A Thornton-Wells John Q Trojanowski Juan C Troncoso Otto Valladares Vivianna M Van Deerlin Linda J Van Eldik Badri N Vardarajan Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Sarah Wishnek Randall L Woltjer Clinton B Wright Steven G Younkin Chang-En Yu Lei Yu

JAMA Neurol 2014 Nov;71(11):1394-404

Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois.

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http://dx.doi.org/10.1001/jamaneurol.2014.1491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314944PMC
November 2014

Idalopirdine for Alzheimer's disease: written in the stars.

Authors:
Lon S Schneider

Lancet Neurol 2014 Nov 5;13(11):1063-1065. Epub 2014 Oct 5.

Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA. Electronic address:

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November 2014

Effect of APOE genotype status on targeted clinical trials outcomes and efficiency in dementia and mild cognitive impairment resulting from Alzheimer's disease.

Alzheimers Dement 2014 May 25;10(3):349-59. Epub 2013 May 25.

University of Southern California Keck School of Medicine, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.jalz.2013.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900604PMC
May 2014

Rethinking the Food and Drug Administration's 2013 guidance on developing drugs for early-stage Alzheimer's disease.

Authors:
Lon S Schneider

Alzheimers Dement 2014 Mar;10(2):247-50

Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2013.12.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979530PMC
March 2014

A new roadmap for drug development for Alzheimer's disease.

Nat Rev Drug Discov 2014 Feb 20;13(2):156. Epub 2013 Dec 20.

Intramural Research Program, National Institute on Aging, National Institutes of Health, Baltimore, Maryland 21224, USA.

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http://dx.doi.org/10.1038/nrd3842-c2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668586PMC
February 2014

Moderators of outcome in late-life depression: a patient-level meta-analysis.

Am J Psychiatry 2013 Jun;170(6):651-9

Department of Psychiatry, University of California San Francisco, USA.

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June 2013

Quantifying an amyloid β model for Alzheimer's disease.

Authors:
Lon S Schneider

Lancet Neurol 2013 Apr 8;12(4):327-8. Epub 2013 Mar 8.

Department of Psychiatry and the Behavioral Sciences, and Department of Neurology, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033, USA.

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April 2013

Alzheimer disease pharmacologic treatment and treatment research.

Authors:
Lon S Schneider

Continuum (Minneap Minn) 2013 Apr;19(2 Dementia):339-57

Keck School of Medicine, University of Southern California, 1540 Alcazar St, CHP-216, Los Angeles, CA 90033, USA.

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April 2013

Biomarker positive and negative subjects in the ADNI cohort: clinical characterization.

Curr Alzheimer Res 2012 12;9(10):1135-41

Department of Biostatistics, School of Public Health, 1665 University Blvd, University of Alabama at Birmingham, Birmingham, AL, USA.

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December 2012

Ginkgo and AD: key negatives and lessons from GuidAge.

Authors:
Lon S Schneider

Lancet Neurol 2012 Oct 6;11(10):836-7. Epub 2012 Sep 6.

Department of Psychiatry, California Alzheimer's Disease Center, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033, USA.

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October 2012

Novel late-onset Alzheimer disease loci variants associate with brain gene expression.

Authors:
Mariet Allen Fanggeng Zou High Seng Chai Curtis S Younkin Julia Crook V Shane Pankratz Minerva M Carrasquillo Christopher N Rowley Asha A Nair Sumit Middha Sooraj Maharjan Thuy Nguyen Li Ma Kimberly G Malphrus Ryan Palusak Sarah Lincoln Gina Bisceglio Constantin Georgescu Debra Schultz Fariborz Rakhshan Christopher P Kolbert Jin Jen Jonathan L Haines Richard Mayeux Margaret A Pericak-Vance Lindsay A Farrer Gerard D Schellenberg Ronald C Petersen Neill R Graff-Radford Dennis W Dickson Steven G Younkin Nilüfer Ertekin-Taner Liana G Apostolova Steven E Arnold Clinton T Baldwin Robert Barber Michael M Barmada Thomas Beach Gary W Beecham Duane Beekly David A Bennett Eileen H Bigio Thomas D Bird Deborah Blacker Bradley F Boeve James D Bowen Adam Boxer James R Burke Jacqueline Buros Joseph D Buxbaum Nigel J Cairns Laura B Cantwell Chuanhai Cao Chris S Carlson Regina M Carney Steven L Carroll Helena C Chui David G Clark Jason Corneveaux Carl W Cotman Paul K Crane Carlos Cruchaga Jeffrey L Cummings Philip L De Jager Charles DeCarli Steven T DeKosky F Yesim Demirci Ramon Diaz-Arrastia Malcolm Dick Beth A Dombroski Ranjan Duara William D Ellis Denis Evans Kelley M Faber Kenneth B Fallon Martin R Farlow Steven Ferris Tatiana M Foroud Matthew Frosch Douglas R Galasko Paul J Gallins Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Sid Gilman Bruno Giordani Jonathan D Glass Alison M Goate Robert C Green John H Growdon Hakon Hakonarson Ronald L Hamilton John Hardy Lindy E Harrell Elizabeth Head Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Gregory A Jicha Lee-Way Jin Gyungah Jun M Ilyas Kamboh Jason Karlawish Anna Karydas John S K Kauwe Jeffrey A Kaye Nancy Kennedy Ronald Kim Edward H Koo Neil W Kowall Patricia Kramer Walter A Kukull James J Lah Eric B Larson Allan I Levey Andrew P Lieberman Oscar L Lopez Kathryn L Lunetta Wendy J Mack Daniel C Marson Eden R Martin Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Thomas J Montine John C Morris Amanda J Myers Adam C Naj Petra Nowotny Joseph E Parisi Daniel P Perl Elaine Peskind Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Ruchita A Rajbhandary Murray Raskind Eric M Reiman Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Ekaterina Rogaeva Roger N Rosenberg Mary Sano Andrew J Saykin Julie A Schneider Lon S Schneider William Seeley Michael L Shelanski Michael A Slifer Charles D Smith Joshua A Sonnen Salvatore Spina Peter St George-Hyslop Robert A Stern Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Debby W Tsuang Vivianna M Van Deerlin Badri Narayan Vardarajan Harry V Vinters Jean Paul Vonsattel Li-San Wang Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Randall L Woltjer

Neurology 2012 Jul 20;79(3):221-8. Epub 2012 Jun 20.

Department of Neuroscience, Biostatistics Unit, Mayo Clinic Florida, Jacksonville, FL, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398432PMC
July 2012

Caregiver burden, health utilities, and institutional service use in Alzheimer's disease.

Int J Geriatr Psychiatry 2012 Apr 10;27(4):382-93. Epub 2011 May 10.

Department of Gerontology and Gerontology Institute, McCormack Graduate School of Policy and Global Studies, University of Massachusetts Boston, Boston, MA, USA.

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http://dx.doi.org/10.1002/gps.2730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204397PMC
April 2012

Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans.

Authors:
Trygve E Bakken J Cooper Roddey Srdjan Djurovic Natacha Akshoomoff David G Amaral Cinnamon S Bloss B J Casey Linda Chang Thomas M Ernst Jeffrey R Gruen Terry L Jernigan Walter E Kaufmann Tal Kenet David N Kennedy Joshua M Kuperman Sarah S Murray Elizabeth R Sowell Lars M Rimol Morten Mattingsdal Ingrid Melle Ingrid Agartz Ole A Andreassen Nicholas J Schork Anders M Dale Michael Weiner Paul Aisen Ronald Petersen Clifford R Jack William Jagust John Q Trojanowki Arthur W Toga Laurel Beckett Robert C Green Andrew J Saykin John Morris Enchi Liu Tom Montine Anthony Gamst Ronald G Thomas Michael Donohue Sarah Walter Devon Gessert Tamie Sather Danielle Harvey John Kornak Anders Dale Matthew Bernstein Joel Felmlee Nick Fox Paul Thompson Norbert Schuff Gene Alexander Charles DeCarli Dan Bandy Robert A Koeppe Norm Foster Eric M Reiman Kewei Chen Chet Mathis Nigel J Cairns Lisa Taylor-Reinwald J Q Trojanowki Les Shaw Virginia M Y Lee Magdalena Korecka Karen Crawford Scott Neu Tatiana M Foroud Steven Potkin Li Shen Zaven Kachaturian Richard Frank Peter J Snyder Susan Molchan Jeffrey Kaye Joseph Quinn Betty Lind Sara Dolen Lon S Schneider Sonia Pawluczyk Bryan M Spann James Brewer Helen Vanderswag Judith L Heidebrink Joanne L Lord Kris Johnson Rachelle S Doody Javier Villanueva-Meyer Munir Chowdhury Yaakov Stern Lawrence S Honig Karen L Bell John C Morris Beau Ances Maria Carroll Sue Leon Mark A Mintun Stacy Schneider Daniel Marson Randall Griffith David Clark Hillel Grossman Effie Mitsis Aliza Romirowsky Leyla deToledo-Morrell Raj C Shah Ranjan Duara Daniel Varon Peggy Roberts Marilyn Albert Chiadi Onyike Stephanie Kielb Henry Rusinek Mony J de Leon Lidia Glodzik Susan De Santi P Murali Doraiswamy Jeffrey R Petrella R Edward Coleman Steven E Arnold Jason H Karlawish David Wolk Charles D Smith Greg Jicha Peter Hardy Oscar L Lopez MaryAnn Oakley Donna M Simpson Anton P Porsteinsson Bonnie S Goldstein Kim Martin Kelly M Makino M Saleem Ismail Connie Brand Ruth A Mulnard Gaby Thai Catherine Mc-Adams-Ortiz Kyle Womack Dana Mathews Mary Quiceno Ramon Diaz-Arrastia Richard King Myron Weiner Kristen Martin-Cook Michael DeVous Allan I Levey James J Lah Janet S Cellar Jeffrey M Burns Heather S Anderson Russell H Swerdlow Liana Apostolova Po H Lu George Bartzokis Daniel H S Silverman Neill R Graff-Radford Francine Parfitt Heather Johnson Martin R Farlow Ann Marie Hake Brandy R Matthews Scott Herring Christopher H van Dyck Richard E Carson Martha G MacAvoy Howard Chertkow Howard Bergman Chris Hosein Sandra Black Bojana Stefanovic Curtis Caldwell Ging-Yuek Robin Hsiung Howard Feldman Benita Mudge Michele Assaly Andrew Kertesz John Rogers Dick Trost Charles Bernick Donna Munic Diana Kerwin Marek-Marsel Mesulam Kristina Lipowski Chuang-Kuo Wu Nancy Johnson Carl Sadowsky Walter Martinez Teresa Villena Raymond Scott Turner Kathleen Johnson Brigid Reynolds Reisa A Sperling Keith A Johnson Gad Marshall Meghan Frey Jerome Yesavage Joy L Taylor Barton Lane Allyson Rosen Jared Tinklenberg Marwan Sabbagh Christine Belden Sandra Jacobson Neil Kowall Ronald Killiany Andrew E Budson Alexander Norbash Patricia Lynn Johnson Thomas O Obisesan Saba Wolday Salome K Bwayo Alan Lerner Leon Hudson Paula Ogrocki Evan Fletcher Owen Carmichael John Olichney Smita Kittur Michael Borrie T-Y Lee Rob Bartha Sterling Johnson Sanjay Asthana Cynthia M Carlsson Steven G Potkin Adrian Preda Dana Nguyen Pierre Tariot Adam Fleisher Stephanie Reeder Vernice Bates Horacio Capote Michelle Rainka Douglas W Scharre Maria Kataki Earl A Zimmerman Dzintra Celmins Alice D Brown Godfrey D Pearlson Karen Blank Karen Anderson Robert B Santulli Eben S Schwartz Kaycee M Sink Jeff D Williamson Pradeep Garg Franklin Watkins Brian R Ott Henry Querfurth Geoffrey Tremont Stephen Salloway Paul Malloy Stephen Correia Howard J Rosen Bruce L Miller Jacobo Mintzer Crystal Flynn Longmire Kenneth Spicer Elizabether Finger Irina Rachinsky Dick Drost Terry Jernigan Connor McCabe Ellen Grant Thomas Ernst Josh Kuperman Yoon Chung Sarah Murray Cinnamon Bloss Burcu Darst Lexi Pritchett Ashley Saito David Amaral Mishaela DiNino Bella Eyngorina Elizabeth Sowell Suzanne Houston Lindsay Soderberg Walter Kaufmann Peter van Zijl Hilda Rizzo-Busack Mohsin Javid Natasha Mehta Erika Ruberry Alisa Powers Bruce Rosen Nitzah Gebhard Holly Manigan Jean Frazier David Kennedy Lauren Yakutis Michael Hill Jeffrey Gruen Joan Bosson-Heenan Heatherly Carlson

Proc Natl Acad Sci U S A 2012 Mar 16;109(10):3985-90. Epub 2012 Feb 16.

Medical Scientist Training Program, University of California at San Diego, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1073/pnas.1105829109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3309762PMC
March 2012

Symptomatic and nonamyloid/tau based pharmacologic treatment for Alzheimer disease.

Cold Spring Harb Perspect Med 2012 Mar;2(3):a006395

University of California, San Diego, California 92093, USA.

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http://dx.doi.org/10.1101/cshperspect.a006395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282492PMC
March 2012

Discontinuing donepezil or starting memantine for Alzheimer's disease.

Authors:
Lon S Schneider

N Engl J Med 2012 Mar;366(10):957-9

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http://dx.doi.org/10.1056/NEJMe1200429DOI Listing
March 2012

Could cholinesterase inhibitors be harmful over the long term?

Authors:
Lon S Schneider

Int Psychogeriatr 2012 Feb;24(2):171-4

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http://dx.doi.org/10.1017/S1041610211002389DOI Listing
February 2012

Effect of second-generation antipsychotics on caregiver burden in Alzheimer's disease.

J Clin Psychiatry 2012 Jan 6;73(1):121-8. Epub 2011 Sep 6.

Veterans Affairs New England Mental Illness Research, Education and Clinical Center, West Haven, CT, USA.

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http://dx.doi.org/10.4088/JCP.10m06574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4040971PMC
January 2012

Risk of mortality among individual antipsychotics in patients with dementia.

Am J Psychiatry 2012 Jan 31;169(1):71-9. Epub 2011 Oct 31.

Ann Arbor VA Center for Clinical Management Research, Serious Mental Illness Treatment, Resource, and Evaluation Center, Ann Arbor, Mich., USA.

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http://dx.doi.org/10.1176/appi.ajp.2011.11030347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269551PMC
January 2012

Estrogen receptor β-selective phytoestrogenic formulation prevents physical and neurological changes in a preclinical model of human menopause.

Menopause 2011 Oct;18(10):1131-42

Department of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1097/gme.0b013e3182175b66DOI Listing
October 2011

Lack of evidence for the efficacy of memantine in mild Alzheimer disease.

Arch Neurol 2011 Aug 11;68(8):991-8. Epub 2011 Apr 11.

University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1001/archneurol.2011.69DOI Listing
August 2011

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.

Authors:
Adam C Naj Gyungah Jun Gary W Beecham Li-San Wang Badri Narayan Vardarajan Jacqueline Buros Paul J Gallins Joseph D Buxbaum Gail P Jarvik Paul K Crane Eric B Larson Thomas D Bird Bradley F Boeve Neill R Graff-Radford Philip L De Jager Denis Evans Julie A Schneider Minerva M Carrasquillo Nilufer Ertekin-Taner Steven G Younkin Carlos Cruchaga John S K Kauwe Petra Nowotny Patricia Kramer John Hardy Matthew J Huentelman Amanda J Myers Michael M Barmada F Yesim Demirci Clinton T Baldwin Robert C Green Ekaterina Rogaeva Peter St George-Hyslop Steven E Arnold Robert Barber Thomas Beach Eileen H Bigio James D Bowen Adam Boxer James R Burke Nigel J Cairns Chris S Carlson Regina M Carney Steven L Carroll Helena C Chui David G Clark Jason Corneveaux Carl W Cotman Jeffrey L Cummings Charles DeCarli Steven T DeKosky Ramon Diaz-Arrastia Malcolm Dick Dennis W Dickson William G Ellis Kelley M Faber Kenneth B Fallon Martin R Farlow Steven Ferris Matthew P Frosch Douglas R Galasko Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Sid Gilman Bruno Giordani Jonathan D Glass John H Growdon Ronald L Hamilton Lindy E Harrell Elizabeth Head Lawrence S Honig Christine M Hulette Bradley T Hyman Gregory A Jicha Lee-Way Jin Nancy Johnson Jason Karlawish Anna Karydas Jeffrey A Kaye Ronald Kim Edward H Koo Neil W Kowall James J Lah Allan I Levey Andrew P Lieberman Oscar L Lopez Wendy J Mack Daniel C Marson Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Joseph E Parisi Daniel P Perl Elaine Peskind Ronald C Petersen Wayne W Poon Joseph F Quinn Ruchita A Rajbhandary Murray Raskind Barry Reisberg John M Ringman Erik D Roberson Roger N Rosenberg Mary Sano Lon S Schneider William Seeley Michael L Shelanski Michael A Slifer Charles D Smith Joshua A Sonnen Salvatore Spina Robert A Stern Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Randall L Woltjer Laura B Cantwell Beth A Dombroski Duane Beekly Kathryn L Lunetta Eden R Martin M Ilyas Kamboh Andrew J Saykin Eric M Reiman David A Bennett John C Morris Thomas J Montine Alison M Goate Deborah Blacker Debby W Tsuang Hakon Hakonarson Walter A Kukull Tatiana M Foroud Jonathan L Haines Richard Mayeux Margaret A Pericak-Vance Lindsay A Farrer Gerard D Schellenberg

Nat Genet 2011 May 3;43(5):436-41. Epub 2011 Apr 3.

The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA.

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http://dx.doi.org/10.1038/ng.801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090745PMC
May 2011

Trends in antipsychotic use in dementia 1999-2007.

Arch Gen Psychiatry 2011 Feb;68(2):190-7

Veterans Affairs Health Services Researchand Development Center for Clinical Management Research, Serious Mental Illness Treatment, Resource, and Evaluation Center, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1001/archgenpsychiatry.2010.200DOI Listing
February 2011

Treatment with cholinesterase inhibitors and memantine of patients in the Alzheimer's Disease Neuroimaging Initiative.

Arch Neurol 2011 Jan;68(1):58-66

Department of Psychiatry and the Behavioral Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1001/archneurol.2010.343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259850PMC
January 2011

Anti-aβ therapeutics in Alzheimer's disease: the need for a paradigm shift.

Neuron 2011 Jan;69(2):203-13

Center for Translational Research in Neurodegenerative Disease and Department of Neuroscience, College of Medicine, University of Florida, 1275 Center Drive BMS J-483, P.O. Box 100159, Gainesville, FL 32610-0244, USA.

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http://dx.doi.org/10.1016/j.neuron.2011.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3058906PMC
January 2011

Fixing Alzheimer disease trials by improving process and methods.

Authors:
Lon S Schneider

Curr Alzheimer Res 2010 Nov;7(7):564-5

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November 2010